Shikang Liang

Affiliations: 
University of Cambridge (UK) 
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"Shikang Liang"
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Liang S, Blundell TL. (2023) Human DNA-dependent protein kinase activation mechanism. Nature Structural & Molecular Biology
Liang S, Thomas SE, Chaplin AK, et al. (2022) Structural insights into inhibitor regulation of the DNA repair protein DNA-PKcs. Nature
Chaplin AK, Hardwick SW, Stavridi AK, et al. (2021) Cryo-EM of NHEJ supercomplexes provides insights into DNA repair. Molecular Cell
Thapar R, Wang JL, Hammel M, et al. (2020) Mechanism of efficient double-strand break repair by a long non-coding RNA. Nucleic Acids Research
Liang S, Chaplin AK, Stavridi AK, et al. (2020) Stages, scaffolds and strings in the spatial organisation of non-homologous end joining: Insights from X-ray diffraction and Cryo-EM. Progress in Biophysics and Molecular Biology
Chaplin AK, Hardwick SW, Liang S, et al. (2020) Dimers of DNA-PK create a stage for DNA double-strand break repair. Nature Structural & Molecular Biology
Thapar R, Wang JL, Hammel M, et al. (2020) Mechanism of efficient double-strand break repair by a long non-coding RNA. Nucleic Acids Research
Kefala Stavridi A, Appleby R, Liang S, et al. (2020) Druggable binding sites in the multicomponent assemblies that characterise DNA double-strand-break repair through non-homologous end joining. Essays in Biochemistry
Wu Q, Liang S, Ochi T, et al. (2019) Understanding the structure and role of DNA-PK in NHEJ: How X-ray diffraction and cryo-EM contribute in complementary ways. Progress in Biophysics and Molecular Biology
Wang JL, Duboc C, Wu Q, et al. (2018) Dissection of DNA double-strand-break repair using novel single-molecule forceps. Nature Structural & Molecular Biology
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