Paulien Hogeweg, PhD

1977-2009 Theoretical Biology/Bioinformatics Utrecht University, Utrecht, Netherlands 
"Paulien Hogeweg"

In 1970 Paulien Hogeweg defined bioinformatics as "the study of informatic processes in biotic systems"


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Christiaan Pieter Raven grad student 1976 Utrecht (DevTree)
Frederik van der Blij grad student 1976 Utrecht (MathTree)
 (Topics in biological pattern analysis)


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Otto Cordero grad student (Evolution Tree)
Martijn A. Huynen grad student Utrecht
Erik van Nimwegen grad student 1999 Utrecht (Plant Biology Tree)
Michael F. Seidl grad student 2013 Utrecht
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von der Dunk SHA, Hogeweg P, Snel B. (2024) Intracellular signaling in proto-eukaryotes evolves to alleviate regulatory conflicts of endosymbiosis. Plos Computational Biology. 20: e1011860
von der Dunk SHA, Hogeweg P, Snel B. (2023) Obligate endosymbiosis enables genome expansion during eukaryogenesis. Communications Biology. 6: 777
von der Dunk SHA, Snel B, Hogeweg P. (2022) Evolution of Complex Regulation for Cell-Cycle Control. Genome Biology and Evolution. 14
van Dijk B, Hogeweg P, Doekes HM, et al. (2020) Slightly beneficial genes are retained by bacteria evolving DNA uptake despite selfish elements. Elife. 9
van Dijk B, Meijer J, Cuypers TD, et al. (2019) Trusting the hand that feeds: microbes evolve to anticipate a serial transfer protocol as individuals or collectives. Bmc Evolutionary Biology. 19: 201
Colizzi ES, Hogeweg P. (2019) Transcriptional Mutagenesis Prevents Ribosomal DNA Deterioration: The Role of Duplications and Deletions. Genome Biology and Evolution. 11: 3207-3217
von der Dunk SHA, Colizzi ES, Hogeweg P. (2017) Evolutionary Conflict Leads to Innovation: Symmetry Breaking in a Spatial Model of RNA-Like Replicators. Life (Basel, Switzerland). 7
Takeuchi N, Hogeweg P, Kaneko K. (2017) The origin of a primordial genome through spontaneous symmetry breaking. Nature Communications. 8: 250
Cuypers TD, Rutten JP, Hogeweg P. (2017) Evolution of evolvability and phenotypic plasticity in virtual cells. Bmc Evolutionary Biology. 17: 60
Takeuchi N, Kaneko K, Hogeweg P. (2016) Evolutionarily stable disequilibrium: endless dynamics of evolution in a stationary population. Proceedings. Biological Sciences / the Royal Society. 283
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