Wendell A. Lim - Related publications

1996- Cellular and Molecular Pharmacology University of California, San Francisco, San Francisco, CA 
Cellular Signaling Systems
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Lee CJ, Lee GE, An HJ, Cho ES, Chen W, Lee JY, Kang HC, Lee HS, Cho YY. F-box Protein βTrCP1 Is a Substrate of Extracellular Signal-regulated Kinase 2. Journal of Cancer Prevention. 26: 174-182. PMID 34703820 DOI: 10.15430/JCP.2021.26.3.174   
2021 Mathien S, Tesnière C, Meloche S. Regulation of Mitogen-Activated Protein Kinase Signaling Pathways by the Ubiquitin-Proteasome System and Its Pharmacological Potential. Pharmacological Reviews. 73: 263-296. PMID 34732541 DOI: 10.1124/pharmrev.120.000170   
2021 Hepworth EMW, Hinton SD. Pseudophosphatases as Regulators of MAPK Signaling. International Journal of Molecular Sciences. 22. PMID 34830476 DOI: 10.3390/ijms222212595   
2021 Mysore VP, Zhou ZW, Ambrogio C, Li L, Kapp JN, Lu C, Wang Q, Tucker MR, Okoro JJ, Nagy-Davidescu G, Bai X, Plückthun A, Jänne PA, Westover KD, Shan Y, et al. A structural model of a Ras-Raf signalosome. Nature Structural & Molecular Biology. 28: 847-857. PMID 34625747 DOI: 10.1038/s41594-021-00667-6   
2021 Sun J, Wu Z, Wu W, Leng J, Lv X, Zhang T, Wang L, Song L. PDGFRβ Recognizes and Binds Bacteria to Activate Src/Stat Pathway in Oysters. Journal of Immunology (Baltimore, Md. : 1950). PMID 34799429 DOI: 10.4049/jimmunol.2100486   
2021 Chen PH, Hu Z, An E, Okeke I, Zheng S, Luo X, Gong A, Jaime-Figueroa S, Crews CM. Modulation of Phosphoprotein Activity by Phosphorylation Targeting Chimeras (PhosTACs). Acs Chemical Biology. PMID 34780684 DOI: 10.1021/acschembio.1c00693   
2021 Yang Y. Functional Selectivity of Dopamine D Receptor Signaling: Retrospect and Prospect. International Journal of Molecular Sciences. 22. PMID 34769344 DOI: 10.3390/ijms222111914   
2021 Padros J, Chatel G, Caron M. Time-resolved Förster Resonance Energy Transfer Assays for Measurement of Endogenous Phosphorylated STAT Proteins in Human Cells. Journal of Visualized Experiments : Jove. PMID 34570089 DOI: 10.3791/62915   
2021 Bumpus TW, Huang S, Tei R, Baskin JM. Click chemistry-enabled CRISPR screening reveals GSK3 as a regulator of PLD signaling. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34810254 DOI: 10.1073/pnas.2025265118   
2021 Reusch B, Bartram MP, Dafinger C, Palacio-Escat N, Wenzel A, Fenton RA, Saez-Rodriguez J, Schermer B, Benzing T, Altmüller J, Beck BB, Rinschen MM. MAGED2 controls vasopressin-induced aquaporin-2 expression in collecting duct cells. Journal of Proteomics. 104424. PMID 34775100 DOI: 10.1016/j.jprot.2021.104424   
2021 Smith TG, Uzozie AC, Chen S, Lange PF. Robust unsupervised deconvolution of linear motifs characterizes 68 protein modifications at proteome scale. Scientific Reports. 11: 22490. PMID 34795380 DOI: 10.1038/s41598-021-01971-3   
2021 Martin CE, Murray AS, Sala-Hamrick KE, Mackinder JR, Harrison EC, Lundgren JG, Varela FA, List K. Posttranslational modifications of serine protease TMPRSS13 regulate zymogen activation, proteolytic activity, and cell surface localization. The Journal of Biological Chemistry. 297: 101227. PMID 34562451 DOI: 10.1016/j.jbc.2021.101227   
2021 Zang Y, Kahsai AW, Pakharukova N, Huang LY, Lefkowitz RJ. The GPCR-β-arrestin complex allosterically activates C-Raf by binding its amino-terminus. The Journal of Biological Chemistry. 101369. PMID 34757127 DOI: 10.1016/j.jbc.2021.101369   
2021 Wang W, Dai Z, Li J, Ouyang J, Li T, Zeng B, Kang L, Jia K, Xi Z, Jia W. A Method for Assaying of Protein Kinase Activity In Vivo and Its Use in Studies of Signal Transduction in Strawberry Fruit Ripening. International Journal of Molecular Sciences. 22. PMID 34638834 DOI: 10.3390/ijms221910495   
2021 Farooq M, Khan AW, Kim MS, Choi S. The Role of Fibroblast Growth Factor (FGF) Signaling in Tissue Repair and Regeneration. Cells. 10. PMID 34831463 DOI: 10.3390/cells10113242   
2021 Enrico TP, Stallaert W, Wick ET, Ngoi P, Wang X, Rubin SM, Brown NG, Purvis J, Emanuele MJ. Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2. Elife. 10. PMID 34851822 DOI: 10.7554/eLife.70691   
2021 Elias RD, Ramaraju B, Deshmukh L. Mechanistic roles of tyrosine phosphorylation in reversible amyloids, autoinhibition, and endosomal membrane association of ALIX. The Journal of Biological Chemistry. 297: 101328. PMID 34688656 DOI: 10.1016/j.jbc.2021.101328   
2021 Agnihotri SK, Kar P, Singh M, Pant G, Mitra K, Bhatt MLB, Sachdev M. Modulation of protein phosphatase 1 gamma 2 during cell division of cervical cancer HeLa cells. Contemporary Oncology (Poznan, Poland). 25: 125-132. PMID 34667439 DOI: 10.5114/wo.2021.107745   
2021 Yan J, Xu W, Lenahan C, Huang L, Wen J, Li G, Hu X, Zheng W, Zhang JH, Tang J. CCR5 Activation Promotes NLRP1-Dependent Neuronal Pyroptosis via CCR5/PKA/CREB Pathway After Intracerebral Hemorrhage. Stroke. STROKEAHA120033285. PMID 34719258 DOI: 10.1161/STROKEAHA.120.033285   
2021 Zhao M, Finlay D, Kwong E, Liddington R, Viollet B, Sasaoka N, Vuori K. Cell adhesion suppresses autophagy via Src/FAK-mediated phosphorylation and inhibition of AMPK. Cellular Signalling. 89: 110170. PMID 34673141 DOI: 10.1016/j.cellsig.2021.110170   
2021 Waschbüsch D, Berndsen K, Lis P, Knebel A, Lam YP, Alessi DR, Khan AR. Structural basis for the specificity of PPM1H phosphatase for Rab GTPases. Embo Reports. e52675. PMID 34580980 DOI: 10.15252/embr.202152675   
2021 Zhang S, Lin X, Hou Q, Hu Z, Wang Y, Wang Z. Regulation of mTORC1 by amino acids in mammalian cells: A general picture of recent advances. Animal Nutrition (Zhongguo Xu Mu Shou Yi Xue Hui). 7: 1009-1023. PMID 34738031 DOI: 10.1016/j.aninu.2021.05.003   
2021 Zhang Z, Ran Y, Xu L, Pan Z, Xie Y. High-dose dexamethasone injection disordered metabolism and multiple protein kinases expression in the mouse kidney. Bioscience Reports. PMID 34735568 DOI: 10.1042/BSR20211847   
2021 Mathis CL, Barrios AM. Histidine phosphorylation in metalloprotein binding sites. Journal of Inorganic Biochemistry. 225: 111606. PMID 34555600 DOI: 10.1016/j.jinorgbio.2021.111606   
2021 Lin ZY, Yun QZ, Wu L, Zhang TW, Yao TZ. Pharmacological basis and new insights of deguelin concerning its anticancer effects. Pharmacological Research. 105935. PMID 34644595 DOI: 10.1016/j.phrs.2021.105935   
2021 Iannetta AA, Minton NE, Uitenbroek AA, Little JL, Stanton CR, Kristich CJ, Hicks LM. IreK-Mediated, Cell Wall-Protective Phosphorylation in . Journal of Proteome Research. 20: 5131-5144. PMID 34672600 DOI: 10.1021/acs.jproteome.1c00635   
2021 Lisa MN, Sogues A, Barilone N, Baumgart M, Gil M, Graña M, Durán R, Biondi RM, Bellinzoni M, Bott M, Alzari PM. A Tetratricopeptide Repeat Scaffold Couples Signal Detection to OdhI Phosphorylation in Metabolic Control by the Protein Kinase PknG. Mbio. e0171721. PMID 34607462 DOI: 10.1128/mBio.01717-21   
2021 Wang W, Mevellec L, Liu A, Struble G, Miller R, Allen SJ, Federowicz K, Wroblowski B, Vialard J, Ahn K, Krosky D. Discovery of an Allosteric, Inactive Conformation-Selective Inhibitor of Full-Length HPK1 Utilizing a Kinase Cascade Assay. Biochemistry. PMID 34608799 DOI: 10.1021/acs.biochem.1c00486   
2021 Brown SL, Ren Y, Suter DM, Mattoo S. A Co-purification Method for Efficient Production and Src Kinase-mediated Phosphorylation of Cortactin. Bio-Protocol. 11: e4158. PMID 34692908 DOI: 10.21769/BioProtoc.4158   
2021 Yang S, Cai W, Shen L, Cao J, Liu C, Hu J, Guan D, He S. A CaCDPK29-CaWRKY27b module promotes CaWRKY40-mediated thermotolerance and immunity to Ralstonia solanacearum in pepper. The New Phytologist. PMID 34854082 DOI: 10.1111/nph.17891   
2021 Li Y, Liu Y, Huang X, Ren J. Analysis of protein phosphorylation combining capillary electrophoresis with ATP analogue labelling technique. Electrophoresis. PMID 34783369 DOI: 10.1002/elps.202100251   
2021 Chellaiah MA. L-Plastin Phosphorylation: Possible Regulation by a TNFR1 Signaling Cascade in Osteoclasts. Cells. 10. PMID 34572081 DOI: 10.3390/cells10092432   
2021 Zhu DW, Yu Q, Sun JJ, Shen YH. Evaluating the Therapeutic Mechanisms of Selected Active Compounds in Thunb. in Pulmonary Fibrosis Network Pharmacology Analysis. Frontiers in Pharmacology. 12: 733618. PMID 34658873 DOI: 10.3389/fphar.2021.733618   
2021 Roffey SE, Litchfield DW. CK2 Regulation: Perspectives in 2021. Biomedicines. 9. PMID 34680478 DOI: 10.3390/biomedicines9101361   
2021 Zhao YT, Fallas JA, Saini S, Ueda G, Somasundaram L, Zhou Z, Xavier Raj I, Xu C, Carter L, Wrenn S, Mathieu J, Sellers DL, Baker D, Ruohola-Baker H. F-domain valency determines outcome of signaling through the angiopoietin pathway. Embo Reports. e53471. PMID 34698433 DOI: 10.15252/embr.202153471   
2021 Carroll DJ, Cao Y, Bochner BS, O'Sullivan JA. Siglec-8 Signals Through a Non-Canonical Pathway to Cause Human Eosinophil Death . Frontiers in Immunology. 12: 737988. PMID 34721399 DOI: 10.3389/fimmu.2021.737988   
2021 Pei H, Wu S, Zheng L, Wang H, Zhang X. Identification of the active compounds and their mechanisms of medicinal and edible Shanzha based on network pharmacology and molecular docking. Journal of Food Biochemistry. e14020. PMID 34825377 DOI: 10.1111/jfbc.14020   
2021 Ortega MA, Fraile-Martínez O, García-Montero C, Ruiz-Grande F, Barrena S, Montoya H, Pekarek L, Zoullas S, Alvarez-Mon MA, Sainz F, Asúnsolo A, Acero J, Álvarez-Mon M, Buján J, García-Honduvilla N, et al. Chronic venous disease patients show increased IRS-4 expression in the great saphenous vein wall. The Journal of International Medical Research. 49: 3000605211041275. PMID 34590920 DOI: 10.1177/03000605211041275   
2021 He L, Jhong JH, Chen Q, Huang KY, Strittmatter K, Kreuzer J, DeRan M, Wu X, Lee TY, Slavov N, Haas W, Marneros AG. Global characterization of macrophage polarization mechanisms and identification of M2-type polarization inhibitors. Cell Reports. 37: 109955. PMID 34731634 DOI: 10.1016/j.celrep.2021.109955   
2021 Zhang G, Shen T, Ren N, Jiang M. Phosphorylation of OsABA2 at Ser197 by OsMPK1 regulates abscisic acid biosynthesis in rice. Biochemical and Biophysical Research Communications. 586: 68-73. PMID 34826703 DOI: 10.1016/j.bbrc.2021.11.067   
2021 Molina E, Hong L, Chefetz I. NUAK Kinases: Brain-Ovary Axis. Cells. 10. PMID 34685740 DOI: 10.3390/cells10102760   
2021 Gao X, Zhang J, Cai G, Du H, Li J, Wang R, Wang Y, Yin J, Zhang W, Zhang H, Huang J. qGL3/OsPPKL1 Induces Phosphorylation of 14-3-3 OsGF14b to Inhibit OsBZR1 Function in Brassinosteroid Signaling. Plant Physiology. PMID 34662408 DOI: 10.1093/plphys/kiab484   
2021 Zhang T, Liu Q, Gao W, Sehgal SA, Wu H. The multifaceted regulation of mitophagy by endogenous metabolites. Autophagy. 1-24. PMID 34583624 DOI: 10.1080/15548627.2021.1975914   
2021 Afinanisa Q, Cho MK, Seong HA. AMPK Localization: A Key to Differential Energy Regulation. International Journal of Molecular Sciences. 22. PMID 34681581 DOI: 10.3390/ijms222010921   
2021 Chen L, Kong X, Fang Y, Paunikar S, Wang X, Brown JAL, Bourke E, Li X, Wang J. Recent Advances in the Role of Discoidin Domain Receptor Tyrosine Kinase 1 and Discoidin Domain Receptor Tyrosine Kinase 2 in Breast and Ovarian Cancer. Frontiers in Cell and Developmental Biology. 9: 747314. PMID 34805157 DOI: 10.3389/fcell.2021.747314   
2021 Wu X, Liu Z, Liao W. The involvement of gaseous signaling molecules in plant MAPK cascades: function and signal transduction. Planta. 254: 127. PMID 34812934 DOI: 10.1007/s00425-021-03792-0   
2021 Blaustein M, Piegari E, Martínez Calejman C, Vila A, Amante A, Manese MV, Zeida A, Abrami L, Veggetti M, Guertin DA, van der Goot FG, Corvi MM, Colman-Lerner A. Akt Is S-Palmitoylated: A New Layer of Regulation for Akt. Frontiers in Cell and Developmental Biology. 9: 626404. PMID 33659252 DOI: 10.3389/fcell.2021.626404   
2021 Li X, Qi Z, Ni D, Lu S, Chen L, Chen X. Markov State Models and Molecular Dynamics Simulations Provide Understanding of the Nucleotide-Dependent Dimerization-Based Activation of LRRK2 ROC Domain. Molecules (Basel, Switzerland). 26. PMID 34577121 DOI: 10.3390/molecules26185647   
2021 Zhang S, Chen H, Li C, Chen B, Gong H, Zhao Y, Qi R. Water-Soluble Tomato Extract Fruitflow Alters the Phosphoproteomic Profile of Collagen-Stimulated Platelets. Frontiers in Pharmacology. 12: 746107. PMID 34646142 DOI: 10.3389/fphar.2021.746107   
2021 Abraham SP, Nita A, Krejci P, Bosakova M. Cilia kinases in skeletal development and homeostasis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. PMID 34582081 DOI: 10.1002/dvdy.426