| Year |
Citation |
Score |
| 2011 |
Kennedy PC, Zhu R, Huang T, Tomsig JL, Mathews TP, David M, Peyruchaud O, Macdonald TL, Lynch KR. Characterization of a sphingosine 1-phosphate receptor antagonist prodrug. The Journal of Pharmacology and Experimental Therapeutics. 338: 879-89. PMID 21632869 DOI: 10.1124/Jpet.111.181552 |
0.647 |
|
| 2008 |
Sun Q, Zhu R, Foss FW, Macdonald TL. In vitro metabolism of a model cyclopropylamine to reactive intermediate: Insights into trovafloxacin-induced hepatotoxicity Chemical Research in Toxicology. 21: 711-719. PMID 18298092 DOI: 10.1021/Tx7003085 |
0.658 |
|
| 2007 |
Zhu R, Snyder AH, Kharel Y, Schaffter L, Sun Q, Kennedy PC, Lynch KR, Macdonald TL. Asymmetric synthesis of conformationally constrained fingolimod analogues--discovery of an orally active sphingosine 1-phosphate receptor type-1 agonist and receptor type-3 antagonist. Journal of Medicinal Chemistry. 50: 6428-35. PMID 17994678 DOI: 10.1021/Jm7010172 |
0.624 |
|
| 2007 |
Sun Q, Zhu R, Foss FW, Macdonald TL. Mechanisms of trovafloxacin hepatotoxicity: Studies of a model cyclopropylamine-containing system Bioorganic and Medicinal Chemistry Letters. 17: 6682-6686. PMID 17976985 DOI: 10.1016/J.Bmcl.2007.10.070 |
0.652 |
|
| 2006 |
Zhu R, Frazier CR, Linden J, Macdonald TL. N6-ethyl-2-alkynyl NECAs, selective human A3 adenosine receptor agonists. Bioorganic & Medicinal Chemistry Letters. 16: 2416-8. PMID 16487705 DOI: 10.1016/J.Bmcl.2006.01.110 |
0.516 |
|
| 2005 |
Kharel Y, Lee S, Snyder AH, Sheasley-O'neill SL, Morris MA, Setiady Y, Zhu R, Zigler MA, Burcin TL, Ley K, Tung KS, Engelhard VH, Macdonald TL, Pearson-White S, Lynch KR. Sphingosine kinase 2 is required for modulation of lymphocyte traffic by FTY720. The Journal of Biological Chemistry. 280: 36865-72. PMID 16093248 DOI: 10.1074/Jbc.M506293200 |
0.533 |
|
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