Kevin Chu, Ph.D. - Publications

Affiliations: 
2013 Pharmaceutical Sciences University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Cancer Nanotechnology

10 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Bowerman CJ, Byrne JD, Chu KS, Schorzman AN, Keeler AW, Sherwood CA, Perry JL, Luft JC, Darr DB, Deal AM, Napier ME, Zamboni WC, Sharpless NE, Perou C, DeSimone JM. Docetaxel-loaded PLGA Nanoparticles Improve Efficacy in Taxane-Resistant Triple-Negative Breast Cancer. Nano Letters. PMID 27966988 DOI: 10.1021/Acs.Nanolett.6B03971  0.511
2016 Sambade M, Deal A, Schorzman A, Luft JC, Bowerman C, Chu K, Karginova O, Swearingen AV, Zamboni W, DeSimone J, Anders CK. Efficacy and pharmacokinetics of a modified acid-labile docetaxel-PRINT(®) nanoparticle formulation against non-small-cell lung cancer brain metastases. Nanomedicine (London, England). PMID 27456556 DOI: 10.2217/Nnm-2016-0147  0.568
2014 Gharpure KM, Chu KS, Bowerman CJ, Miyake T, Pradeep S, Mangala SL, Han HD, Rupaimoole R, Armaiz-Pena GN, Rahhal TB, Wu SY, Luft JC, Napier ME, Lopez-Berestein G, DeSimone JM, et al. Metronomic docetaxel in PRINT nanoparticles and EZH2 silencing have synergistic antitumor effect in ovarian cancer. Molecular Cancer Therapeutics. 13: 1750-7. PMID 24755199 DOI: 10.1158/1535-7163.Mct-13-0930  0.494
2014 Chu KS, Finniss MC, Schorzman AN, Kuijer JL, Luft JC, Bowerman CJ, Napier ME, Haroon ZA, Zamboni WC, DeSimone JM. Particle replication in nonwetting templates nanoparticles with tumor selective alkyl silyl ether docetaxel prodrug reduces toxicity. Nano Letters. 14: 1472-6. PMID 24552251 DOI: 10.1021/Nl4046558  0.549
2014 Finniss MC, Chu KS, Bowerman CJ, Luft JC, Haroon ZA, Desimone JM. A versatile acid-labile linker for antibody-drug conjugates Medchemcomm. 5: 1355-1358. DOI: 10.1039/C4Md00150H  0.366
2013 Chu KS, Schorzman AN, Finniss MC, Bowerman CJ, Peng L, Luft JC, Madden AJ, Wang AZ, Zamboni WC, DeSimone JM. Nanoparticle drug loading as a design parameter to improve docetaxel pharmacokinetics and efficacy. Biomaterials. 34: 8424-9. PMID 23899444 DOI: 10.1016/J.Biomaterials.2013.07.038  0.448
2013 Morton SW, Herlihy KP, Shopsowitz KE, Deng ZJ, Chu KS, Bowerman CJ, Desimone JM, Hammond PT. Scalable manufacture of built-to-order nanomedicine: spray-assisted layer-by-layer functionalization of PRINT nanoparticles. Advanced Materials (Deerfield Beach, Fla.). 25: 4707-13. PMID 23813892 DOI: 10.1002/Adma.201302025  0.701
2013 Chu KS, Hasan W, Rawal S, Walsh MD, Enlow EM, Luft JC, Bridges AS, Kuijer JL, Napier ME, Zamboni WC, DeSimone JM. Plasma, tumor and tissue pharmacokinetics of Docetaxel delivered via nanoparticles of different sizes and shapes in mice bearing SKOV-3 human ovarian carcinoma xenograft. Nanomedicine : Nanotechnology, Biology, and Medicine. 9: 686-93. PMID 23219874 DOI: 10.1016/J.Nano.2012.11.008  0.686
2013 Madden AJ, Rawal S, Chu K, Sandison K, Schell R, Feng L, Ma P, Mumper R, DeSimone J, Zamboni WC. Abstract 3355: Evaluation of the efficiency of tumor and tissue delivery of carrier mediated agents (CMA) and small molecule (SM) agents in mice using a novel pharmacokinetic (PK) metric relative distribution index over time (RDI-OT). Cancer Research. 73: 3355-3355. DOI: 10.1158/1538-7445.Am2013-3355  0.486
2012 Hasan W, Chu K, Gullapalli A, Dunn SS, Enlow EM, Luft JC, Tian S, Napier ME, Pohlhaus PD, Rolland JP, DeSimone JM. Delivery of multiple siRNAs using lipid-coated PLGA nanoparticles for treatment of prostate cancer. Nano Letters. 12: 287-92. PMID 22165988 DOI: 10.1021/Nl2035354  0.524
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