☰

Wooseok Han, Ph.D. - Publications

Affiliations: 
2003 University of Toronto, Toronto, ON, Canada 
Area:
Organic Synthesis
Tree Info Similar researchers PubMed Report error

14 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Han W, Ding Y, Chen Z, Langowski JL, Bellamacina C, Rico A, Nishiguchi GA, Lan J, Atallah G, Lindvall M, Lin S, Zang R, Feucht P, Zavorotinskaya T, Dai Y, et al. Synthesis and Structure-Activity Relationship of Tetra-Substituted Cyclohexyl Diol Inhibitors of Proviral Insertion of Moloney Virus (PIM) Kinases. Journal of Medicinal Chemistry. PMID 33258605 DOI: 10.1021/acs.jmedchem.0c01279  0.347
2020 Han W, Ma X, Balibar CJ, Baxter Rath CM, Benton B, Bermingham A, Casey F, Chie-Leon B, Cho MK, Frank AO, Frommlet A, Ho CM, Lee PS, Li M, Lingel A, et al. Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis. Journal of the American Chemical Society. PMID 32064871 DOI: 10.1021/Jacs.9B13530  0.341
2016 Han W, Ding Y, Xu Y, Pfister K, Zhu S, Warne R, Doyle M, Aikawa M, Amiri P, Appleton B, Darrin SD, Fanidi A, Shafer CM. Discovery of a Selective and Potent Inhibitor of Mitogen-Activated Protein Kinase-Interacting Kinases 1 and 2 (MNK1/2) Utilizing Structure-Based Drug Design. Journal of Medicinal Chemistry. PMID 27002243 DOI: 10.1021/Acs.Jmedchem.5B01657  0.379
2016 Nishiguchi GA, Burger MT, Han W, Lan J, Atallah G, Tamez V, Lindvall M, Bellamacina C, Garcia P, Feucht P, Zavorotinskaya T, Dai Y, Wong K. Design, synthesis and structure activity relationship of potent pan-PIM kinase inhibitors derived from the pyridyl carboxamide scaffold. Bioorganic & Medicinal Chemistry Letters. PMID 26995528 DOI: 10.1016/J.Bmcl.2016.03.037  0.396
2016 Han W, Menezes DL, Xu Y, Knapp MS, Elling R, Burger MT, Ni ZJ, Smith A, Lan J, Williams TE, Verhagen J, Huh K, Merritt H, Chan J, Kaufman S, et al. Discovery of imidazo[1,2-a]-pyridine inhibitors of pan-PI3 kinases that are efficacious in a mouse xenograft model. Bioorganic & Medicinal Chemistry Letters. PMID 26774655 DOI: 10.1016/J.Bmcl.2016.01.003  0.398
2015 Burger MT, Nishiguchi G, Han W, Lan J, Simmons R, Atallah G, Ding Y, Tamez V, Zhang Y, Mathur M, Muller K, Bellamacina C, Lindvall MK, Zang R, Huh K, et al. Identification of N-(4-((1R,3S,5S)-3-Amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide (PIM447), a Potent and Selective Proviral Insertion Site of Moloney Murine Leukemia (PIM) 1, 2, and 3 Kinase Inhibitor in Clinical Trials for Hematological Malignancies. Journal of Medicinal Chemistry. PMID 26505898 DOI: 10.1021/Acs.Jmedchem.5B01275  0.4
2015 Bagdanoff JT, Jain R, Han W, Zhu S, Madiera AM, Lee PS, Ma X, Poon D. Tetrahydropyrrolo-diazepenones as inhibitors of ERK2 kinase. Bioorganic & Medicinal Chemistry Letters. 25: 3788-92. PMID 26259804 DOI: 10.1016/J.Bmcl.2015.07.091  0.365
2015 Bagdanoff JT, Jain R, Han W, Poon D, Lee PS, Bellamacina C, Lindvall M. Ligand efficient tetrahydro-pyrazolopyridines as inhibitors of ERK2 kinase. Bioorganic & Medicinal Chemistry Letters. PMID 26144345 DOI: 10.1016/J.Bmcl.2015.06.063  0.35
2013 Burger MT, Han W, Lan J, Nishiguchi G, Bellamacina C, Lindval M, Atallah G, Ding Y, Mathur M, McBride C, Beans EL, Muller K, Tamez V, Zhang Y, Huh K, et al. Structure Guided Optimization, in Vitro Activity, and in Vivo Activity of Pan-PIM Kinase Inhibitors. Acs Medicinal Chemistry Letters. 4: 1193-7. PMID 24900629 DOI: 10.1021/Ml400307J  0.379
2013 Pecchi S, Ni ZJ, Han W, Smith A, Lan J, Burger M, Merritt H, Wiesmann M, Chan J, Kaufman S, Knapp MS, Janssen J, Huh K, Voliva CF. Structure guided optimization of a fragment hit to imidazopyridine inhibitors of PI3K. Bioorganic & Medicinal Chemistry Letters. 23: 4652-6. PMID 23820386 DOI: 10.1016/J.Bmcl.2013.06.010  0.375
2011 Nishiguchi GA, Atallah G, Bellamacina C, Burger MT, Ding Y, Feucht PH, Garcia PD, Han W, Klivansky L, Lindvall M. Discovery of novel 3,5-disubstituted indole derivatives as potent inhibitors of Pim-1, Pim-2, and Pim-3 protein kinases. Bioorganic & Medicinal Chemistry Letters. 21: 6366-9. PMID 21945284 DOI: 10.1016/J.Bmcl.2011.08.105  0.397
2004 Scott ME, Han W, Lautens M. A highly diastereoselective MgI2-mediated ring expansion of methylenecyclopropanes. Organic Letters. 6: 3309-12. PMID 15355039 DOI: 10.1021/Ol048769U  0.411
2003 Lautens M, Han W, Liu JH. MgI(2)-mediated ring expansions of secondary methylenecyclopropyl amides. Journal of the American Chemical Society. 125: 4028-9. PMID 12670206 DOI: 10.1021/Ja028967L  0.403
2002 Lautens M, Han W. Divergent selectivity in MgI(2)-mediated ring expansions of methylenecyclopropyl amides and imides. Journal of the American Chemical Society. 124: 6312-6. PMID 12033859 DOI: 10.1021/Ja011110O  0.418
Show low-probability matches.