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Norbert Perrimon - Publications

Affiliations: 
1986- Genetics Harvard University, Cambridge, MA, United States 
Website:
https://perrimon.med.harvard.edu/
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446 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Song S, Cho B, Weiner AT, Nissen SB, Ojeda Naharros I, Sanchez Bosch P, Suyama K, Hu Y, He L, Svinkina T, Udeshi ND, Carr SA, Perrimon N, Axelrod JD. Protein phosphatase 1 regulates core PCP signaling. Embo Reports. e56997. PMID 37975164 DOI: 10.15252/embr.202356997  0.649
2023 Song S, Cho B, Weiner AT, Nissen SB, Naharros IO, Bosch PS, Suyama K, Hu Y, He L, Svinkina T, Udeshi ND, Carr SA, Perrimon N, Axelrod JD. Protein phosphatase 1 regulates core PCP signaling. Biorxiv : the Preprint Server For Biology. PMID 37745534 DOI: 10.1101/2023.09.12.556998  0.647
2023 Petsakou A, Liu Y, Liu Y, Comjean A, Hu Y, Perrimon N. Cholinergic neurons trigger epithelial Ca currents to heal the gut. Nature. PMID 37722602 DOI: 10.1038/s41586-023-06627-y  0.778
2023 Petsakou A, Liu Y, Liu Y, Comjean A, Hu Y, Perrimon N. Epithelial Ca waves triggered by enteric neurons heal the gut. Biorxiv : the Preprint Server For Biology. PMID 37645990 DOI: 10.1101/2023.08.14.553227  0.773
2023 Zirin J, Jusiak B, Lopes R, Ewen-Campen B, Bosch J, Villalta C, Forman C, Hu Y, Mohr S, Perrimon N. Expanding the Drosophila toolkit for dual control of gene expression. Biorxiv : the Preprint Server For Biology. PMID 37645802 DOI: 10.1101/2023.08.15.553399  0.8
2023 Ewen-Campen B, Luan H, Xu J, Singh R, Joshi N, Thakkar T, Berger B, White BH, Perrimon N. split-intein Gal4 provides intersectional genetic labeling that is repressible by Gal80. Proceedings of the National Academy of Sciences of the United States of America. 120: e2304730120. PMID 37276389 DOI: 10.1073/pnas.2304730120  0.742
2023 Xia B, Viswanatha R, Hu Y, Mohr SE, Perrimon N. Pooled genome-wide CRISPR activation screening for rapamycin resistance genes in cells. Elife. 12. PMID 37078570 DOI: 10.7554/eLife.85542  0.759
2023 Ewen-Campen B, Luan H, Xu J, Singh R, Joshi N, Thakkar T, Berger B, White BH, Perrimon N. split-intein Gal4 provides intersectional genetic labeling that is fully repressible by Gal80. Biorxiv : the Preprint Server For Biology. PMID 36993523 DOI: 10.1101/2023.03.24.534001  0.742
2023 He L, Perrimon N. Synthetic Notch receptors and their applications to study cell-cell contacts in vivo. Developmental Cell. 58: 171-173. PMID 36750017 DOI: 10.1016/j.devcel.2023.01.001  0.376
2022 Kim AR, Xu J, Cheloha R, Mohr SE, Zirin J, Ploegh HL, Perrimon N. NanoTag Nanobody Tools for Drosophila In Vitro and In Vivo Studies. Current Protocols. 2: e628. PMID 36571722 DOI: 10.1002/cpz1.628  0.722
2022 Hu Y, Ewen-Campen B, Comjean A, Rodiger J, Mohr SE, Perrimon N. Paralog Explorer: A resource for mining information about paralogs in common research organisms. Computational and Structural Biotechnology Journal. 20: 6570-6577. PMID 36467589 DOI: 10.1016/j.csbj.2022.11.041  0.726
2022 Petsakou A, Perrimon N. Bioelectric regulation of intestinal stem cells. Trends in Cell Biology. PMID 36396487 DOI: 10.1016/j.tcb.2022.10.003  0.789
2022 Bosch JA, Ugur B, Pichardo-Casas I, Rabasco J, Escobedo F, Zuo Z, Brown B, Celniker S, Sinclair DA, Bellen HJ, Perrimon N. Two neuronal peptides encoded from a single transcript regulate mitochondrial complex III in . Elife. 11. PMID 36346220 DOI: 10.7554/eLife.82709  0.435
2022 Petsakou A, Perrimon N. No sugar, just protein please - says the fly. Nature Metabolism. PMID 36344763 DOI: 10.1038/s42255-022-00665-y  0.765
2022 Xu Y, Viswanatha R, Sitsel O, Roderer D, Zhao H, Ashwood C, Voelcker C, Tian S, Raunser S, Perrimon N, Dong M. CRISPR screens in Drosophila cells identify Vsg as a Tc toxin receptor. Nature. PMID 36171290 DOI: 10.1038/s41586-022-05250-7  0.736
2022 Dalton HM, Viswanatha R, Brathwaite R, Zuno JS, Berman AR, Rushforth R, Mohr SE, Perrimon N, Chow CY. A genome-wide CRISPR screen identifies DPM1 as a modifier of DPAGT1 deficiency and ER stress. Plos Genetics. 18: e1010430. PMID 36166480 DOI: 10.1371/journal.pgen.1010430  0.741
2022 Han S, Dias GB, Basting PJ, Viswanatha R, Perrimon N, Bergman CM. Local assembly of long reads enables phylogenomics of transposable elements in a polyploid cell line. Nucleic Acids Research. PMID 36156149 DOI: 10.1093/nar/gkac794  0.736
2022 Ghosh AC, Hu Y, Tattikota SG, Liu Y, Comjean A, Perrimon N. Modeling exercise using optogenetically contractible Drosophila larvae. Bmc Genomics. 23: 623. PMID 36042416 DOI: 10.1186/s12864-022-08845-6  0.767
2022 Yang R, Meyer AS, Droujinine IA, Udeshi ND, Hu Y, Guo J, McMahon JA, Carey DK, Xu C, Fang Q, Sha J, Qin S, Rocco D, Wohlschlegel J, Ting AY, ... ... Perrimon N, et al. A genetic model for proximity labelling of the mammalian secretome. Open Biology. 12: 220149. PMID 35946312 DOI: 10.1098/rsob.220149  0.782
2022 Fell CW, Hagelkruys A, Cicvaric A, Horrer M, Liu L, Li JSS, Stadlmann J, Polyansky AA, Mereiter S, Tejada MA, Kokotović T, Achuta VS, Scaramuzza A, Twyman KA, Morrow MM, ... ... Perrimon N, et al. FIBCD1 is an endocytic GAG receptor associated with a novel neurodevelopmental disorder. Embo Molecular Medicine. e15829. PMID 35916241 DOI: 10.15252/emmm.202215829  0.574
2022 Kanca O, Zirin J, Hu Y, Tepe B, Dutta D, Lin WW, Ma L, Ge M, Zuo Z, Liu LP, Levis RW, Perrimon N, Bellen HJ. An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR mediated homologous recombination. Elife. 11. PMID 35723254 DOI: 10.7554/eLife.76077  0.752
2022 Xu J, Liu Y, Li H, Tarashansky AJ, Kalicki CH, Hung RJ, Hu Y, Comjean A, Kolluru SS, Wang B, Quake SR, Luo L, McMahon AP, Dow JAT, Perrimon N. Transcriptional and functional motifs defining renal function revealed by single-nucleus RNA sequencing. Proceedings of the National Academy of Sciences of the United States of America. 119: e2203179119. PMID 35696569 DOI: 10.1073/pnas.2203179119  0.366
2022 Viswanatha R, Mameli E, Rodiger J, Merckaert P, Feitosa-Suntheimer F, Colpitts TM, Mohr SE, Hu Y, Perrimon N. Author Correction: Bioinformatic and cell-based tools for pooled CRISPR knockout screening in mosquitos. Nature Communications. 13: 1813. PMID 35354810 DOI: 10.1038/s41467-022-29489-w  0.724
2022 Li H, Janssens J, De Waegeneer M, Kolluru SS, Davie K, Gardeux V, Saelens W, David FPA, Brbić M, Spanier K, Leskovec J, McLaughlin CN, Xie Q, Jones RC, Brueckner K, ... ... Perrimon N, et al. Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly. Science (New York, N.Y.). 375: eabk2432. PMID 35239393 DOI: 10.1126/science.abk2432  0.797
2022 Xu J, Kim AR, Cheloha RW, Fischer FA, Li JSS, Feng Y, Stoneburner E, Binari R, Mohr SE, Zirin J, Ploegh HL, Perrimon N. Protein visualization and manipulation in through the use of epitope tags recognized by nanobodies. Elife. 11. PMID 35076390 DOI: 10.7554/eLife.74326  0.708
2021 Zirin J, Bosch J, Viswanatha R, Mohr SE, Perrimon N. State-of-the-art CRISPR for in vivo and cell-based studies in Drosophila. Trends in Genetics : Tig. PMID 34933779 DOI: 10.1016/j.tig.2021.11.006  0.8
2021 Viswanatha R, Mameli E, Rodiger J, Merckaert P, Feitosa-Suntheimer F, Colpitts TM, Mohr SE, Hu Y, Perrimon N. Bioinformatic and cell-based tools for pooled CRISPR knockout screening in mosquitos. Nature Communications. 12: 6825. PMID 34819517 DOI: 10.1038/s41467-021-27129-3  0.751
2021 Tattikota SG, Perrimon N. Preparation of Larval Blood Cells for Single-cell RNA Sequencing. Bio-Protocol. 11: e4127. PMID 34541045 DOI: 10.21769/BioProtoc.4127  0.762
2021 Chatterjee N, Perrimon N. What fuels the fly: Energy metabolism in and its application to the study of obesity and diabetes. Science Advances. 7. PMID 34108216 DOI: 10.1126/sciadv.abg4336  0.737
2021 Hu Y, Tattikota SG, Liu Y, Comjean A, Gao Y, Forman C, Kim G, Rodiger J, Papatheodorou I, Dos Santos G, Mohr SE, Perrimon N. DRscDB: A single-cell RNA-seq resource for data mining and data comparison across species. Computational and Structural Biotechnology Journal. 19: 2018-2026. PMID 33995899 DOI: 10.1016/j.csbj.2021.04.021  0.764
2021 Droujinine IA, Meyer AS, Wang D, Udeshi ND, Hu Y, Rocco D, McMahon JA, Yang R, Guo J, Mu L, Carey DK, Svinkina T, Zeng R, Branon T, Tabatabai A, ... ... Perrimon N, et al. Proteomics of protein trafficking by in vivo tissue-specific labeling. Nature Communications. 12: 2382. PMID 33888706 DOI: 10.1038/s41467-021-22599-x  0.782
2021 Mohr SE, Tattikota SG, Xu J, Zirin J, Hu Y, Perrimon N. Methods and tools for spatial mapping of single-cell RNAseq clusters in Drosophila. Genetics. PMID 33713129 DOI: 10.1093/genetics/iyab019  0.789
2021 Tang HW, Weng JH, Lee WX, Hu Y, Gu L, Cho S, Lee G, Binari R, Li C, Cheng ME, Kim AR, Xu J, Shen Z, Xu C, Asara JM, ... ... Perrimon N, et al. mTORC1-chaperonin CCT signaling regulates mA RNA methylation to suppress autophagy. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33649236 DOI: 10.1073/pnas.2021945118  0.324
2021 Ghosh AC, Tattikota SG, Liu Y, Comjean A, Hu Y, Barrera V, Ho Sui SJ, Perrimon N. Correction: PDGF/VEGF signaling from muscles to hepatocyte-like cells protects against obesity. Elife. 10. PMID 33475495 DOI: 10.7554/eLife.66685  0.775
2020 Ghosh AC, Tattikota SG, Liu Y, Comjean A, Hu Y, Barrera V, Ho Sui SJ, Perrimon N. PDGF/VEGF signaling from muscles to hepatocyte-like cells protects against obesity. Elife. 9. PMID 33107824 DOI: 10.7554/eLife.56969  0.797
2020 Hu Y, Comjean A, Rodiger J, Liu Y, Gao Y, Chung V, Zirin J, Perrimon N, Mohr SE. FlyRNAi.org-the database of the Drosophila RNAi screening center and transgenic RNAi project: 2021 update. Nucleic Acids Research. PMID 33104800 DOI: 10.1093/nar/gkaa936  0.705
2020 Xia B, Amador G, Viswanatha R, Zirin J, Mohr SE, Perrimon N. CRISPR-based engineering of gene knockout cells by homology-directed insertion in polyploid Drosophila S2R+ cells. Nature Protocols. 15: 3478-3498. PMID 32958931 DOI: 10.1038/S41596-020-0383-8  0.807
2020 Bosch JA, Chen CL, Perrimon N. Proximity-dependent labeling methods for proteomic profiling in living cells: An update. Wiley Interdisciplinary Reviews. Developmental Biology. e392. PMID 32909689 DOI: 10.1002/wdev.392  0.316
2020 Ewen-Campen B, Comyn T, Vogt E, Perrimon N. No Evidence that Wnt Ligands Are Required for Planar Cell Polarity in Drosophila. Cell Reports. 32: 108121. PMID 32905771 DOI: 10.1016/J.Celrep.2020.108121  0.762
2020 Cho B, Yoon SH, Lee D, Koranteng F, Tattikota SG, Cha N, Shin M, Do H, Hu Y, Oh SY, Lee D, Vipin Menon A, Moon SJ, Perrimon N, Nam JW, et al. Single-cell transcriptome maps of myeloid blood cell lineages in Drosophila. Nature Communications. 11: 4483. PMID 32900993 DOI: 10.1038/S41467-020-18135-Y  0.781
2020 Ewen-Campen B, Perrimon N. Expanding the horizons of genome editing in the fruit fly with Cas12a. Proceedings of the National Academy of Sciences of the United States of America. PMID 32883881 DOI: 10.1073/Pnas.2016446117  0.74
2020 Tattikota SG, Cho B, Liu Y, Hu Y, Barrera V, Steinbaugh MJ, Yoon SH, Comjean A, Li F, Dervis F, Hung RJ, Nam JW, Ho Sui S, Shim J, Perrimon N. A single-cell survey of blood. Elife. 9. PMID 32396065 DOI: 10.7554/Elife.54818  0.795
2020 Kim K, Lane EA, Saftien A, Wang H, Xu Y, Wirtz-Peitz F, Perrimon N. as a model for studying cystic fibrosis pathophysiology of the gastrointestinal system. Proceedings of the National Academy of Sciences of the United States of America. PMID 32345720 DOI: 10.1073/Pnas.1913127117  0.76
2020 Zirin J, Hu Y, Liu L, Yang-Zhou D, Colbeth R, Yan D, Ewen-Campen B, Tao R, Vogt E, VanNest S, Cavers C, Villalta C, Comjean A, Sun J, Wang X, ... ... Perrimon N, et al. Large-Scale Transgenic Resource Collections for Loss- and Gain-of-Function Studies. Genetics. PMID 32071193 DOI: 10.1534/Genetics.119.302964  0.802
2020 Hung RJ, Hu Y, Kirchner R, Liu Y, Xu C, Comjean A, Tattikota SG, Li F, Song W, Ho Sui S, Perrimon N. A cell atlas of the adult midgut. Proceedings of the National Academy of Sciences of the United States of America. PMID 31915294 DOI: 10.1073/pnas.1916820117  0.792
2020 Bosch JA, Knight S, Kanca O, Zirin J, Yang-Zhou D, Hu Y, Rodiger J, Amador G, Bellen HJ, Perrimon N, Mohr SE. Use of the CRISPR-Cas9 System in Drosophila Cultured Cells to Introduce Fluorescent Tags into Endogenous Genes. Current Protocols in Molecular Biology. 130: e112. PMID 31869524 DOI: 10.1002/cpmb.112  0.754
2019 Xu C, Franklin B, Tang HW, Regimbald-Dumas Y, Hu Y, Ramos J, Bosch JA, Villalta C, He X, Perrimon N. An in vivo RNAi screen uncovers the role of AdoR signaling and adenosine deaminase in controlling intestinal stem cell activity. Proceedings of the National Academy of Sciences of the United States of America. PMID 31852821 DOI: 10.1073/pnas.1900103117  0.41
2019 Kwon YV, Zhao B, Xu C, Lee J, Chen CL, Vinayagam A, Edgar BA, Perrimon N. The role of translationally controlled tumor protein in proliferation of intestinal stem cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 31843907 DOI: 10.1073/pnas.1910850116  0.499
2019 Chen CL, Rodiger J, Chung V, Viswanatha R, Mohr SE, Hu Y, Perrimon N. SNP-CRISPR: A Web Tool for SNP-Specific Genome Editing. G3 (Bethesda, Md.). PMID 31822517 DOI: 10.1534/G3.119.400904  0.729
2019 Amamoto R, Garcia MD, West ER, Choi J, Lapan SW, Lane EA, Perrimon N, Cepko CL. Probe-Seq enables transcriptional profiling of specific cell types from heterogeneous tissue by RNA-based isolation. Elife. 8. PMID 31815670 DOI: 10.7554/eLife.51452  0.342
2019 Bult CJ, Blake JA, Calvi BR, Cherry JM, DiFrancesco V, Fullem R, Howe KL, Kaufman T, Mungall C, Perrimon N, Shimoyama M, Sternberg PW, Thomas P, Westerfield M. The Alliance of Genome Resources: Building a Modern Data Ecosystem for Model Organism Databases. Genetics. 213: 1189. PMID 31796553 DOI: 10.1534/Genetics.119.302523  0.307
2019 Viswanatha R, Brathwaite R, Hu Y, Li Z, Rodiger J, Merckaert P, Chung V, Mohr SE, Perrimon N. Pooled CRISPR Screens in Drosophila Cells. Current Protocols in Molecular Biology. 129: e111. PMID 31763777 DOI: 10.1002/cpmb.111  0.743
2019 Bosch JA, Colbeth R, Zirin J, Perrimon N. Gene Knock-Ins in Using Homology-Independent Insertion of Universal Donor Plasmids. Genetics. PMID 31685521 DOI: 10.1534/Genetics.119.302819  0.747
2019 Kanca O, Zirin J, Garcia-Marques J, Knight SM, Yang-Zhou D, Amador G, Chung H, Zuo Z, Ma L, He Y, Lin WW, Fang Y, Ge M, Yamamoto S, Schulze KL, ... ... Perrimon N, et al. An efficient CRISPR-based strategy to insert small and large fragments of DNA using short homology arms. Elife. 8. PMID 31674908 DOI: 10.7554/Elife.51539  0.782
2019 Mohr SE, Perrimon N. : a simple system for understanding complexity. Disease Models & Mechanisms. 12. PMID 31562251 DOI: 10.1242/dmm.041871  0.323
2019 Parkhitko AA, Jouandin P, Mohr SE, Perrimon N. Methionine metabolism and methyltransferases in the regulation of aging and lifespan extension across species. Aging Cell. e13034. PMID 31460700 DOI: 10.1111/acel.13034  0.307
2019 Droujinine IA, Perrimon N. The Multidimensional Organization of Interorgan Communication Networks. Developmental Cell. 50: 395-396. PMID 31430450 DOI: 10.1016/j.devcel.2019.07.029  0.78
2019 Silver JT, Wirtz-Peitz F, Simões S, Pellikka M, Yan D, Binari R, Nishimura T, Li Y, Harris TJC, Perrimon N, Tepass U. Apical polarity proteins recruit the RhoGEF Cysts to promote junctional myosin assembly. The Journal of Cell Biology. PMID 31409654 DOI: 10.1083/Jcb.201807106  0.789
2019 Ahmad M, He L, Perrimon N. Regulation of insulin and adipokinetic hormone/glucagon production in flies. Wiley Interdisciplinary Reviews. Developmental Biology. e360. PMID 31379062 DOI: 10.1002/wdev.360  0.546
2019 Zirin J, Ni X, Sack LM, Yang-Zhou D, Hu Y, Brathwaite R, Bulyk ML, Elledge SJ, Perrimon N. Interspecies analysis of MYC targets identifies tRNA synthetases as mediators of growth and survival in MYC-overexpressing cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 31262815 DOI: 10.1073/Pnas.1821863116  0.739
2019 He L, Binari R, Huang J, Falo-Sanjuan J, Perrimon N. study of gene expression with an enhanced dual-color fluorescent transcriptional timer. Elife. 8. PMID 31140975 DOI: 10.7554/eLife.46181  0.447
2019 Dumesic PA, Egan DF, Gut P, Tran MT, Parisi A, Chatterjee N, Jedrychowski M, Paschini M, Kazak L, Wilensky SE, Dou F, Bogoslavski D, Cartier JA, Perrimon N, Kajimura S, et al. An Evolutionarily Conserved uORF Regulates PGC1α and Oxidative Metabolism in Mice, Flies, and Bluefin Tuna. Cell Metabolism. PMID 31105043 DOI: 10.1016/J.Cmet.2019.04.013  0.747
2019 Hunter GL, He L, Perrimon N, Charras G, Giniger E, Baum B. A role for actomyosin contractility in Notch signaling. Bmc Biology. 17: 12. PMID 30744634 DOI: 10.1186/S12915-019-0625-9  0.472
2019 Xu C, Tang HW, Hung RJ, Hu Y, Ni X, Housden BE, Perrimon N. The Septate Junction Protein Tsp2A Restricts Intestinal Stem Cell Activity via Endocytic Regulation of aPKC and Hippo Signaling. Cell Reports. 26: 670-688.e6. PMID 30650359 DOI: 10.1016/j.celrep.2018.12.079  0.394
2019 Kanca O, Zirin J, Garcia-Marques J, Knight SM, Yang-Zhou D, Amador G, Chung H, Zuo Z, Ma L, He Y, Lin W, Fang Y, Ge M, Yamamoto S, Schulze KL, ... ... Perrimon N, et al. Author response: An efficient CRISPR-based strategy to insert small and large fragments of DNA using short homology arms Elife. DOI: 10.7554/Elife.51539.024  0.73
2019 Nicholson H, Housden B, Perrimon N, Kaelin WG. Abstract C124: HIF-independent synthetic lethality between CDK4/6 inhibition and VHL loss across species Molecular Cancer Therapeutics. 18. DOI: 10.1158/1535-7163.Targ-19-C124  0.366
2018 Xu C, Ericsson M, Perrimon N. Understanding cellular signaling and systems biology with precision: A perspective from ultrastructure and organelle studies in the midgut. Current Opinion in Systems Biology. 11: 24-31. PMID 31595264 DOI: 10.1016/j.coisb.2018.07.003  0.382
2018 He L, Ahmad M, Perrimon N. Mechanosensitive channels and their functions in stem cell differentiation. Experimental Cell Research. PMID 30500393 DOI: 10.1016/j.yexcr.2018.11.016  0.576
2018 Parasram K, Bernardon N, Hammoud M, Chang H, He L, Perrimon N, Karpowicz P. Intestinal Stem Cells Exhibit Conditional Circadian Clock Function. Stem Cell Reports. 11: 1287-1301. PMID 30428387 DOI: 10.1016/J.Stemcr.2018.10.010  0.792
2018 Doupé DP, Marshall OJ, Dayton H, Brand AH, Perrimon N. intestinal stem and progenitor cells are major sources and regulators of homeostatic niche signals. Proceedings of the National Academy of Sciences of the United States of America. PMID 30404917 DOI: 10.1073/Pnas.1719169115  0.585
2018 Hu Y, Sopko R, Chung V, Foos M, Studer RA, Landry SD, Liu D, Rabinow L, Gnad F, Beltrao P, Perrimon N. iProteinDB: An Integrative Database of Post-translational Modifications. G3 (Bethesda, Md.). PMID 30397019 DOI: 10.1534/G3.118.200637  0.331
2018 Okamoto N, Viswanatha R, Bittar R, Li Z, Haga-Yamanaka S, Perrimon N, Yamanaka N. A Membrane Transporter Is Required for Steroid Hormone Uptake in Drosophila. Developmental Cell. PMID 30293839 DOI: 10.1016/J.Devcel.2018.09.012  0.76
2018 Song W, Ghosh AC, Cheng D, Perrimon N. Endocrine Regulation of Energy Balance by Drosophila TGF-β/Activins. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. PMID 30264417 DOI: 10.1002/Bies.201800044  0.566
2018 Branon TC, Bosch JA, Sanchez AD, Udeshi ND, Svinkina T, Carr SA, Feldman JL, Perrimon N, Ting AY. Efficient proximity labeling in living cells and organisms with TurboID. Nature Biotechnology. PMID 30125270 DOI: 10.1038/Nbt.4201  0.358
2018 Viswanatha R, Li Z, Hu Y, Perrimon N. Pooled genome-wide CRISPR screening for basal and context-specific fitness gene essentiality in cells. Elife. 7. PMID 30051818 DOI: 10.7554/Elife.36333  0.771
2018 Ewen-Campen B, Perrimon N. Co-selection: A Method for Enriching CRISPR/Cas9-Edited Alleles in . G3 (Bethesda, Md.). PMID 29934375 DOI: 10.1534/G3.118.200498  0.724
2018 Jia Y, Xu RG, Ren X, Ewen-Campen B, Rajakumar R, Zirin J, Yang-Zhou D, Zhu R, Wang F, Mao D, Peng P, Qiao HH, Wang X, Liu LP, Xu B, ... ... Perrimon N, et al. Next-generation CRISPR/Cas9 transcriptional activation in using flySAM. Proceedings of the National Academy of Sciences of the United States of America. PMID 29666231 DOI: 10.1073/Pnas.1800677115  0.79
2018 Tang HW, Hu Y, Chen CL, Xia B, Zirin J, Yuan M, Asara JM, Rabinow L, Perrimon N. The TORC1-Regulated CPA Complex Rewires an RNA Processing Network to Drive Autophagy and Metabolic Reprogramming. Cell Metabolism. PMID 29606597 DOI: 10.1016/J.Cmet.2018.02.023  0.715
2018 Zhang T, Song W, Li Z, Qian W, Wei L, Yang Y, Wang W, Zhou X, Meng M, Peng J, Xia Q, Perrimon N, Cheng D. Krüppel homolog 1 represses insect ecdysone biosynthesis by directly inhibiting the transcription of steroidogenic enzymes. Proceedings of the National Academy of Sciences of the United States of America. PMID 29567866 DOI: 10.1073/pnas.1800435115  0.318
2018 Lee PT, Zirin J, Kanca O, Lin WW, Schulze KL, Li-Kroeger D, Tao R, Devereaux C, Hu Y, Chung V, Fang Y, He Y, Pan H, Ge M, Zuo Z, ... ... Perrimon N, et al. A gene-specificlibrary for. Elife. 7. PMID 29565247 DOI: 10.7554/Elife.35574  0.807
2018 Guo J, Tang HW, Li J, Perrimon N, Yan D. Xio is a component of thesex determination pathway and RNA-methyladenosine methyltransferase complex. Proceedings of the National Academy of Sciences of the United States of America. PMID 29555755 DOI: 10.1073/Pnas.1720945115  0.602
2018 He L, Si G, Huang J, Samuel ADT, Perrimon N. Mechanical regulation of stem-cell differentiation by the stretch-activated Piezo channel. Nature. PMID 29414942 DOI: 10.1038/Nature25744  0.477
2018 Viswanatha R, Li Z, Hu Y, Perrimon N. Author response: Pooled genome-wide CRISPR screening for basal and context-specific fitness gene essentiality in Drosophila cells Elife. DOI: 10.7554/Elife.36333.036  0.764
2018 Lee P, Zirin J, Kanca O, Lin W, Schulze KL, Li-Kroeger D, Tao R, Devereaux C, Hu Y, Chung V, Fang Y, He Y, Pan H, Ge M, Zuo Z, ... ... Perrimon N, et al. Author response: A gene-specific T2A-GAL4 library for Drosophila Elife. DOI: 10.7554/Elife.35574.023  0.757
2017 Mohr SE, Rudd K, Hu Y, Song WR, Gilly Q, Buckner M, Housden BE, Kelley C, Zirin J, Tao R, Amador G, Sierzputowska K, Comjean A, Perrimon N. Zinc Detoxification: A Functional Genomics and Transcriptomics Analysis in Drosophila melanogaster Cultured Cells. G3 (Bethesda, Md.). PMID 29223976 DOI: 10.1534/G3.117.300447  0.731
2017 Housden BE, Li Z, Kelley C, Wang Y, Hu Y, Valvezan AJ, Manning BD, Perrimon N. Improved detection of synthetic lethal interactions in Drosophila cells using variable dose analysis (VDA). Proceedings of the National Academy of Sciences of the United States of America. 114: E10755-E10762. PMID 29183982 DOI: 10.1073/Pnas.1713362114  0.306
2017 Hu Y, Vinayagam A, Nand A, Comjean A, Chung V, Hao T, Mohr SE, Perrimon N. Molecular Interaction Search Tool (MIST): an integrated resource for mining gene and protein interaction data. Nucleic Acids Research. PMID 29155944 DOI: 10.1093/nar/gkx1116  0.304
2017 Valvezan AJ, Turner M, Belaid A, Lam HC, Miller SK, McNamara MC, Baglini C, Housden BE, Perrimon N, Kwiatkowski DJ, Asara JM, Henske EP, Manning BD. mTORC1 Couples Nucleotide Synthesis to Nucleotide Demand Resulting in a Targetable Metabolic Vulnerability. Cancer Cell. PMID 29056426 DOI: 10.1016/J.Ccell.2017.09.013  0.301
2017 Rajan A, Housden BE, Wirtz-Peitz F, Holderbaum L, Perrimon N. A Mechanism Coupling Systemic Energy Sensing to Adipokine Secretion. Developmental Cell. 43: 83-98.e6. PMID 29017032 DOI: 10.1016/J.Devcel.2017.09.007  0.782
2017 Ewen-Campen B, Mohr SE, Hu Y, Perrimon N. Accessing the Phenotype Gap: Enabling Systematic Investigation of Paralog Functional Complexity with CRISPR. Developmental Cell. 43: 6-9. PMID 29017030 DOI: 10.1016/J.Devcel.2017.09.020  0.733
2017 Ewen-Campen B, Yang-Zhou D, Fernandes VR, González DP, Liu LP, Tao R, Ren X, Sun J, Hu Y, Zirin J, Mohr SE, Ni JQ, Perrimon N. Optimized strategy for in vivo Cas9-activation in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. PMID 28808002 DOI: 10.1073/Pnas.1707635114  0.807
2017 Song W, Owusu-Ansah E, Hu Y, Cheng D, Ni X, Zirin J, Perrimon N. Activin signaling mediates muscle-to-adipose communication in a mitochondria dysfunction-associated obesity model. Proceedings of the National Academy of Sciences of the United States of America. PMID 28739899 DOI: 10.1073/Pnas.1708037114  0.775
2017 Lee HJ, Jedrychowski MP, Vinayagam A, Wu N, Shyh-Chang N, Hu Y, Min-Wen C, Moore JK, Asara JM, Lyssiotis CA, Perrimon N, Gygi SP, Cantley LC, Kirschner MW. Proteomic and Metabolomic Characterization of a Mammalian Cellular Transition from Quiescence to Proliferation. Cell Reports. 20: 721-736. PMID 28723573 DOI: 10.1016/J.Celrep.2017.06.074  0.314
2017 Hu Y, Comjean A, Mohr SE, FlyBase Consortium T, Perrimon N. Gene2Function: An Integrated Online Resource for Gene Function Discovery. G3 (Bethesda, Md.). PMID 28663344 DOI: 10.1534/g3.117.043885  0.303
2017 Teleman AA, Perrimon N. Open questions: completing the parts list and finding the integrating signals. Bmc Biology. 15: 47. PMID 28595578 DOI: 10.1186/s12915-017-0388-0  0.34
2017 Xu C, Luo J, He L, Montell C, Perrimon N. Oxidative stress induces stem cell proliferation via TRPA1/RyR-mediated Ca(2+) signaling in the Drosophila midgut. Elife. 6. PMID 28561738 DOI: 10.7554/Elife.22441  0.626
2017 Wang J, Al-Ouran R, Hu Y, Kim SY, Wan YW, Wangler MF, Yamamoto S, Chao HT, Comjean A, Mohr SE, Perrimon N, Liu Z, Bellen HJ. MARRVEL: Integration of Human and Model Organism Genetic Resources to Facilitate Functional Annotation of the Human Genome. American Journal of Human Genetics. PMID 28502612 DOI: 10.1016/J.Ajhg.2017.04.010  0.526
2017 He L, Huang J, Perrimon N. Development of an optimized synthetic Notch receptor as an in vivo cell-cell contact sensor. Proceedings of the National Academy of Sciences of the United States of America. PMID 28490499 DOI: 10.1073/pnas.1703205114  0.48
2017 Chatterjee N, Perrimon N. Thermogenesis by THADA. Developmental Cell. 41: 1-2. PMID 28399393 DOI: 10.1016/J.Devcel.2017.03.021  0.746
2017 Chen CL, Perrimon N. Proximity-dependent labeling methods for proteomic profiling in living cells. Wiley Interdisciplinary Reviews. Developmental Biology. PMID 28387482 DOI: 10.1002/wdev.272  0.319
2017 Hu Y, Comjean A, Perrimon N, Mohr SE. The Drosophila Gene Expression Tool (DGET) for expression analyses. Bmc Bioinformatics. 18: 98. PMID 28187709 DOI: 10.1186/s12859-017-1509-z  0.346
2017 Song W, Cheng D, Hong S, Sappe B, Hu Y, Wei N, Zhu C, O'Connor MB, Pissios P, Perrimon N. Midgut-Derived Activin Regulates Glucagon-like Action in the Fat Body and Glycemic Control. Cell Metabolism. 25: 386-399. PMID 28178568 DOI: 10.1016/j.cmet.2017.01.002  0.41
2017 Xu C, Luo J, He L, Montell C, Perrimon N. Author response: Oxidative stress induces stem cell proliferation via TRPA1/RyR-mediated Ca2+ signaling in the Drosophila midgut Elife. DOI: 10.7554/Elife.22441.040  0.554
2017 Perrimon N. Abstract IA11: Combinatorial screens in Drosophila cells Molecular Cancer Therapeutics. 16. DOI: 10.1158/1538-8514.Synthleth-Ia11  0.341
2016 Hu Y, Comjean A, Roesel C, Vinayagam A, Flockhart I, Zirin J, Perkins L, Perrimon N, Mohr SE. FlyRNAi.org-the database of the Drosophila RNAi screening center and transgenic RNAi project: 2017 update. Nucleic Acids Research. PMID 27924039 DOI: 10.1093/Nar/Gkw977  0.721
2016 Housden BE, Muhar M, Gemberling M, Gersbach CA, Stainier DY, Seydoux G, Mohr SE, Zuber J, Perrimon N. Loss-of-function genetic tools for animal models: cross-species and cross-platform differences. Nature Reviews. Genetics. PMID 27795562 DOI: 10.1038/Nrg.2016.118  0.343
2016 Droujinine IA, Perrimon N. Interorgan Communication Pathways in Physiology: Focus on Drosophila. Annual Review of Genetics. PMID 27732790 DOI: 10.1146/annurev-genet-121415-122024  0.775
2016 Vinayagam A, Kulkarni MM, Sopko R, Sun X, Hu Y, Nand A, Villalta C, Moghimi A, Yang X, Mohr SE, Hong P, Asara JM, Perrimon N. An Integrative Analysis of the InR/PI3K/Akt Network Identifies the Dynamic Response to Insulin Signaling. Cell Reports. 16: 3062-3074. PMID 27626673 DOI: 10.1016/J.Celrep.2016.08.029  0.311
2016 Housden BE, Perrimon N. Cas9-Mediated Genome Engineering in Drosophila melanogaster. Cold Spring Harbor Protocols. 2016: pdb.top086843. PMID 27587786 DOI: 10.1101/pdb.top086843  0.316
2016 Housden BE, Hu Y, Perrimon N. Design and Generation of Drosophila Single Guide RNA Expression Constructs. Cold Spring Harbor Protocols. 2016: pdb.prot090779. PMID 27587779 DOI: 10.1101/pdb.prot090779  0.341
2016 Ammeux N, Housden BE, Georgiadis A, Hu Y, Perrimon N. Mapping signaling pathway cross-talk in Drosophila cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 27528688 DOI: 10.1073/pnas.1610432113  0.39
2016 Petsakou A, Perrimon N. "ISN't Thirst Sweet?" Says the Fly. Cell. 166: 796-7. PMID 27518557 DOI: 10.1016/j.cell.2016.07.038  0.773
2016 Fagegaltier D, Falciatori I, Czech B, Castel S, Perrimon N, Simcox A, Hannon GJ. Oncogenic transformation of Drosophila somatic cells induces a functional piRNA pathway. Genes & Development. 30: 1623-35. PMID 27474441 DOI: 10.1101/Gad.284927.116  0.393
2016 Mohr SE, Hu Y, Ewen-Campen B, Housden BE, Viswanatha R, Perrimon N. CRISPR guide RNA design for research applications. The Febs Journal. PMID 27276584 DOI: 10.1111/Febs.13777  0.772
2016 Hunter GL, Hadjivasiliou Z, Bonin H, He L, Perrimon N, Charras G, Baum B. Coordinated control of Notch-Delta signalling and cell cycle progression drives lateral inhibition mediated tissue patterning. Development (Cambridge, England). PMID 27226324 DOI: 10.1242/Dev.134213  0.492
2016 Harris KP, Zhang YV, Piccioli ZD, Perrimon N, Littleton JT. The postsynaptic t-SNARE Syntaxin 4 controls traffic of Neuroligin 1 and Synaptotagmin 4 to regulate retrograde signaling. Elife. 5. PMID 27223326 DOI: 10.7554/eLife.13881  0.321
2016 Chavez A, Tuttle M, Pruitt BW, Ewen-Campen B, Chari R, Ter-Ovanesyan D, Haque SJ, Cecchi RJ, Kowal EJ, Buchthal J, Housden BE, Perrimon N, Collins JJ, Church G. Comparison of Cas9 activators in multiple species. Nature Methods. PMID 27214048 DOI: 10.1038/Nmeth.3871  0.746
2016 Vinayagam A, Gibson TE, Lee HJ, Yilmazel B, Roesel C, Hu Y, Kwon Y, Sharma A, Liu YY, Perrimon N, Barabási AL. Controllability analysis of the directed human protein interaction network identifies disease genes and drug targets. Proceedings of the National Academy of Sciences of the United States of America. PMID 27091990 DOI: 10.1073/Pnas.1603992113  0.447
2016 Doupé DP, Perrimon N. Toward a Systems Understanding of Signaling Pathway Function. Current Topics in Developmental Biology. 117: 221-36. PMID 26969980 DOI: 10.1016/bs.ctdb.2015.11.005  0.37
2016 Perrimon N, Bonini NM, Dhillon P. Fruit flies on the front line: the translational impact of Drosophila. Disease Models & Mechanisms. 9: 229-31. PMID 26935101 DOI: 10.1242/dmm.024810  0.34
2016 Ma M, Zhao H, Zhao H, Binari R, Perrimon N, Li Z. Wildtype adult stem cells, unlike tumor cells, are resistant to cellular damages in Drosophila. Developmental Biology. PMID 26845534 DOI: 10.1016/j.ydbio.2016.01.040  0.321
2016 Breitkopf SB, Yang X, Begley MJ, Kulkarni M, Chiu YH, Turke AB, Lauriol J, Yuan M, Qi J, Engelman JA, Hong P, Kontaridis MI, Cantley LC, Perrimon N, Asara JM. A Cross-Species Study of PI3K Protein-Protein Interactions Reveals the Direct Interaction of P85 and SHP2. Scientific Reports. 6: 20471. PMID 26839216 DOI: 10.1038/Srep20471  0.321
2015 Dequéant ML, Fagegaltier D, Hu Y, Spirohn K, Simcox A, Hannon GJ, Perrimon N. Discovery of progenitor cell signatures by time-series synexpression analysis during Drosophila embryonic cell immortalization. Proceedings of the National Academy of Sciences of the United States of America. PMID 26438832 DOI: 10.1073/Pnas.1517729112  0.396
2015 Kuhn H, Sopko R, Coughlin M, Perrimon N, Mitchison T. The Atg1-Tor pathway regulates yolk catabolism in Drosophila embryos. Development (Cambridge, England). PMID 26395483 DOI: 10.1242/Jcs.183491  0.348
2015 Owusu-Ansah E, Perrimon N. Stress Signaling Between Organs in Metazoa. Annual Review of Cell and Developmental Biology. PMID 26393775 DOI: 10.1146/Annurev-Cellbio-100814-125523  0.711
2015 Chen CL, Hu Y, Udeshi ND, Lau TY, Wirtz-Peitz F, He L, Ting AY, Carr SA, Perrimon N. Proteomic mapping in live Drosophila tissues using an engineered ascorbate peroxidase. Proceedings of the National Academy of Sciences of the United States of America. PMID 26362788 DOI: 10.1073/Pnas.1515623112  0.78
2015 Housden BE, Valvezan AJ, Kelley C, Sopko R, Hu Y, Roesel C, Lin S, Buckner M, Tao R, Yilmazel B, Mohr SE, Manning BD, Perrimon N. Identification of potential drug targets for tuberous sclerosis complex by synthetic screens combining CRISPR-based knockouts with RNAi. Science Signaling. 8: rs9. PMID 26350902 DOI: 10.1126/Scisignal.Aab3729  0.385
2015 Yan D, Perrimon N. spenito is required for sex determination in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. 112: 11606-11. PMID 26324914 DOI: 10.1073/Pnas.1515891112  0.609
2015 Perkins LA, Holderbaum L, Tao R, Hu Y, Sopko R, McCall K, Yang-Zhou D, Flockhart I, Binari R, Shim HS, Miller A, Housden A, Foos M, Randkelv S, Kelley C, ... ... Perrimon N, et al. The Transgenic RNAi Project at Harvard Medical School: Resources and Validation. Genetics. PMID 26320097 DOI: 10.1534/Genetics.115.180208  0.595
2015 Lin S, Ewen-Campen B, Ni X, Housden BE, Perrimon N. In Vivo Transcriptional Activation Using CRISPR-Cas9 in Drosophila. Genetics. PMID 26245833 DOI: 10.1534/Genetics.115.181065  0.754
2015 Akbari OS, Bellen HJ, Bier E, Bullock SL, Burt A, Church GM, Cook KR, Duchek P, Edwards OR, Esvelt KM, Gantz VM, Golic KG, Gratz SJ, Harrison MM, Hayes KR, ... ... Perrimon N, et al. BIOSAFETY. Safeguarding gene drive experiments in the laboratory. Science (New York, N.Y.). 349: 927-9. PMID 26229113 DOI: 10.1126/Science.Aac7932  0.491
2015 Mohr SE, Hu Y, Rudd K, Buckner M, Gilly Q, Foster B, Sierzputowska K, Comjean A, Ye B, Perrimon N. Reagent and Data Resources for Investigation of RNA Binding Protein Functions in Drosophila melanogaster Cultured Cells. G3 (Bethesda, Md.). PMID 26199285 DOI: 10.1534/g3.115.019364  0.352
2015 Gordon WR, Zimmerman B, He L, Miles LJ, Huang J, Tiyanont K, McArthur DG, Aster JC, Perrimon N, Loparo JJ, Blacklow SC. Mechanical Allostery: Evidence for a Force Requirement in the Proteolytic Activation of Notch. Developmental Cell. 33: 729-36. PMID 26051539 DOI: 10.1016/J.Devcel.2015.05.004  0.417
2015 Kwon Y, Song W, Droujinine IA, Hu Y, Asara JM, Perrimon N. Systemic organ wasting induced by localized expression of the secreted insulin/IGF antagonist ImpL2. Developmental Cell. 33: 36-46. PMID 25850671 DOI: 10.1016/J.Devcel.2015.02.012  0.791
2015 Sopko R, Lin YB, Makhijani K, Alexander B, Perrimon N, Brückner K. A systems-level interrogation identifies regulators of Drosophila blood cell number and survival. Plos Genetics. 11: e1005056. PMID 25749252 DOI: 10.1371/journal.pgen.1005056  0.694
2015 Chavez A, Scheiman J, Vora S, Pruitt BW, Tuttle M, P R Iyer E, Lin S, Kiani S, Guzman CD, Wiegand DJ, Ter-Ovanesyan D, Braff JL, Davidsohn N, Housden BE, Perrimon N, et al. Highly efficient Cas9-mediated transcriptional programming. Nature Methods. 12: 326-8. PMID 25730490 DOI: 10.1038/Nmeth.3312  0.347
2015 Zirin J, Nieuwenhuis J, Samsonova A, Tao R, Perrimon N. Regulators of autophagosome formation in Drosophila muscles. Plos Genetics. 11: e1005006. PMID 25692684 DOI: 10.1371/Journal.Pgen.1005006  0.733
2015 Leshchiner ES, Parkhitko A, Bird GH, Luccarelli J, Bellairs JA, Escudero S, Opoku-Nsiah K, Godes M, Perrimon N, Walensky LD. Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices. Proceedings of the National Academy of Sciences of the United States of America. 112: 1761-6. PMID 25624485 DOI: 10.1073/Pnas.1413185112  0.319
2014 Housden BE, Lin S, Perrimon N. Cas9-based genome editing in Drosophila. Methods in Enzymology. 546: 415-39. PMID 25398351 DOI: 10.1016/B978-0-12-801185-0.00019-2  0.314
2014 Sopko R, Foos M, Vinayagam A, Zhai B, Binari R, Hu Y, Randklev S, Perkins LA, Gygi SP, Perrimon N. Combining genetic perturbations and proteomics to examine kinase-phosphatase networks in Drosophila embryos. Developmental Cell. 31: 114-27. PMID 25284370 DOI: 10.1016/J.Devcel.2014.07.027  0.308
2014 Droujinine IA, Yan D, Perrimon N. A sharp end to sugary Wingless travels. The Journal of Cell Biology. 206: 819-21. PMID 25267292 DOI: 10.1083/Jcb.201408115  0.783
2014 Amcheslavsky A, Song W, Li Q, Nie Y, Bragatto I, Ferrandon D, Perrimon N, Ip YT. Enteroendocrine cells support intestinal stem-cell-mediated homeostasis in Drosophila. Cell Reports. 9: 32-9. PMID 25263551 DOI: 10.1016/j.celrep.2014.08.052  0.359
2014 Gerstein MB, Rozowsky J, Yan KK, Wang D, Cheng C, Brown JB, Davis CA, Hillier L, Sisu C, Li JJ, Pei B, Harmanci AO, Duff MO, Djebali S, Alexander RP, ... ... Perrimon N, et al. Comparative analysis of the transcriptome across distant species. Nature. 512: 445-8. PMID 25164755 DOI: 10.1038/Nature13424  0.517
2014 Housden BE, Perrimon N. Spatial and temporal organization of signaling pathways. Trends in Biochemical Sciences. 39: 457-64. PMID 25155749 DOI: 10.1016/j.tibs.2014.07.008  0.347
2014 Mohr SE, Smith JA, Shamu CE, Neumüller RA, Perrimon N. RNAi screening comes of age: improved techniques and complementary approaches. Nature Reviews. Molecular Cell Biology. 15: 591-600. PMID 25145850 DOI: 10.1038/nrm3860  0.362
2014 Yilmazel B, Hu Y, Sigoillot F, Smith JA, Shamu CE, Perrimon N, Mohr SE. Online GESS: prediction of miRNA-like off-target effects in large-scale RNAi screen data by seed region analysis. Bmc Bioinformatics. 15: 192. PMID 24934636 DOI: 10.1186/1471-2105-15-192  0.347
2014 Zhou R, Mohr S, Hannon GJ, Perrimon N. Inducing RNAi in Drosophila cells by soaking with dsRNA. Cold Spring Harbor Protocols. 2014. PMID 24786505 DOI: 10.1101/Pdb.Prot080747  0.335
2014 Doupé DP, Perrimon N. Visualizing and manipulating temporal signaling dynamics with fluorescence-based tools. Science Signaling. 7: re1. PMID 24692594 DOI: 10.1126/scisignal.2005077  0.36
2014 Brown JB, Boley N, Eisman R, May GE, Stoiber MH, Duff MO, Booth BW, Wen J, Park S, Suzuki AM, Wan KH, Yu C, Zhang D, Carlson JW, Cherbas L, ... ... Perrimon N, et al. Diversity and dynamics of the Drosophila transcriptome. Nature. 512: 393-9. PMID 24670639 DOI: 10.1038/Nature12962  0.53
2014 Mohr SE, Hu Y, Kim K, Housden BE, Perrimon N. Resources for functional genomics studies in Drosophila melanogaster. Genetics. 197: 1-18. PMID 24653003 DOI: 10.1534/genetics.113.154344  0.317
2014 Griffin R, Binari R, Perrimon N. Genetic odyssey to generate marked clones in Drosophila mosaics. Proceedings of the National Academy of Sciences of the United States of America. 111: 4756-63. PMID 24623854 DOI: 10.1073/pnas.1403218111  0.335
2014 Markstein M, Dettorre S, Cho J, Neumüller RA, Craig-Müller S, Perrimon N. Systematic screen of chemotherapeutics in Drosophila stem cell tumors. Proceedings of the National Academy of Sciences of the United States of America. 111: 4530-5. PMID 24616500 DOI: 10.1073/pnas.1401160111  0.78
2014 Owusu-Ansah E, Perrimon N. Modeling metabolic homeostasis and nutrient sensing in Drosophila: implications for aging and metabolic diseases. Disease Models & Mechanisms. 7: 343-50. PMID 24609035 DOI: 10.1242/Dmm.012989  0.699
2014 Yan D, Neumüller RA, Buckner M, Ayers K, Li H, Hu Y, Yang-Zhou D, Pan L, Wang X, Kelley C, Vinayagam A, Binari R, Randklev S, Perkins LA, Xie T, ... ... Perrimon N, et al. A regulatory network of Drosophila germline stem cell self-renewal. Developmental Cell. 28: 459-73. PMID 24576427 DOI: 10.1016/J.Devcel.2014.01.020  0.62
2014 Vinayagam A, Zirin J, Roesel C, Hu Y, Yilmazel B, Samsonova AA, Neumüller RA, Mohr SE, Perrimon N. Integrating protein-protein interaction networks with phenotypes reveals signs of interactions. Nature Methods. 11: 94-9. PMID 24240319 DOI: 10.1038/Nmeth.2733  0.721
2014 Shulman JM, Imboywa S, Giagtzoglou N, Powers MP, Hu Y, Devenport D, Chipendo P, Chibnik LB, Diamond A, Perrimon N, Brown NH, De Jager PL, Feany MB. Functional screening in Drosophila identifies Alzheimer's disease susceptibility genes and implicates Tau-mediated mechanisms. Human Molecular Genetics. 23: 870-7. PMID 24067533 DOI: 10.1093/Hmg/Ddt478  0.331
2014 Tipping M, Perrimon N. Drosophila as a model for context-dependent tumorigenesis. Journal of Cellular Physiology. 229: 27-33. PMID 23836429 DOI: 10.1002/jcp.24427  0.763
2014 Perrimon N. Signaling in time and space Bmc Genomics. 15. DOI: 10.1186/1471-2164-15-S2-O18  0.387
2013 Sun X, Hong P, Kulkarni M, Kwon Y, Perrimon N. PPIRank - an advanced method for ranking protein-protein interations in TAP/MS data. Proteome Science. 11: S16. PMID 24565074 DOI: 10.1186/1477-5956-11-S1-S16  0.377
2013 Droujinine IA, Perrimon N. Defining the interorgan communication network: systemic coordination of organismal cellular processes under homeostasis and localized stress. Frontiers in Cellular and Infection Microbiology. 3: 82. PMID 24312902 DOI: 10.3389/fcimb.2013.00082  0.792
2013 Zirin J, Nieuwenhuis J, Perrimon N. Role of autophagy in glycogen breakdown and its relevance to chloroquine myopathy. Plos Biology. 11: e1001708. PMID 24265594 DOI: 10.1371/Journal.Pbio.1001708  0.712
2013 Owusu-Ansah E, Song W, Perrimon N. Muscle mitohormesis promotes longevity via systemic repression of insulin signaling. Cell. 155: 699-712. PMID 24243023 DOI: 10.1016/J.Cell.2013.09.021  0.693
2013 Ren X, Sun J, Housden BE, Hu Y, Roesel C, Lin S, Liu LP, Yang Z, Mao D, Sun L, Wu Q, Ji JY, Xi J, Mohr SE, Xu J, ... Perrimon N, et al. Optimized gene editing technology for Drosophila melanogaster using germ line-specific Cas9. Proceedings of the National Academy of Sciences of the United States of America. 110: 19012-7. PMID 24191015 DOI: 10.1073/Pnas.1318481110  0.321
2013 Kwon Y, Vinayagam A, Sun X, Dephoure N, Gygi SP, Hong P, Perrimon N. The Hippo signaling pathway interactome. Science (New York, N.Y.). 342: 737-40. PMID 24114784 DOI: 10.1126/Science.1243971  0.484
2013 Xiong XP, Kurthkoti K, Chang KY, Lichinchi G, De N, Schneemann A, MacRae IJ, Rana TM, Perrimon N, Zhou R. Core small nuclear ribonucleoprotein particle splicing factor SmD1 modulates RNA interference in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 110: 16520-5. PMID 24067655 DOI: 10.1073/Pnas.1315803110  0.353
2013 Zirin J, Cheng D, Dhanyasi N, Cho J, Dura JM, Vijayraghavan K, Perrimon N. Ecdysone signaling at metamorphosis triggers apoptosis of Drosophila abdominal muscles. Developmental Biology. 383: 275-84. PMID 24051228 DOI: 10.1016/J.Ydbio.2013.08.029  0.712
2013 Neumüller RA, Gross T, Samsonova AA, Vinayagam A, Buckner M, Founk K, Hu Y, Sharifpoor S, Rosebrock AP, Andrews B, Winston F, Perrimon N. Conserved regulators of nucleolar size revealed by global phenotypic analyses. Science Signaling. 6: ra70. PMID 23962978 DOI: 10.1126/Scisignal.2004145  0.368
2013 Hu Y, Sopko R, Foos M, Kelley C, Flockhart I, Ammeux N, Wang X, Perkins L, Perrimon N, Mohr SE. FlyPrimerBank: an online database for Drosophila melanogaster gene expression analysis and knockdown evaluation of RNAi reagents. G3 (Bethesda, Md.). 3: 1607-16. PMID 23893746 DOI: 10.1534/G3.113.007021  0.347
2013 Hu Y, Roesel C, Flockhart I, Perkins L, Perrimon N, Mohr SE. UP-TORR: online tool for accurate and Up-to-Date annotation of RNAi Reagents. Genetics. 195: 37-45. PMID 23792952 DOI: 10.1534/Genetics.113.151340  0.362
2013 Yin Z, Sadok A, Sailem H, McCarthy A, Xia X, Li F, Garcia MA, Evans L, Barr AR, Perrimon N, Marshall CJ, Wong ST, Bakal C. A screen for morphological complexity identifies regulators of switch-like transitions between discrete cell shapes. Nature Cell Biology. 15: 860-71. PMID 23748611 DOI: 10.1038/Ncb2764  0.687
2013 Silva-Ayala D, López T, Gutiérrez M, Perrimon N, López S, Arias CF. Genome-wide RNAi screen reveals a role for the ESCRT complex in rotavirus cell entry. Proceedings of the National Academy of Sciences of the United States of America. 110: 10270-5. PMID 23733942 DOI: 10.1073/pnas.1304932110  0.385
2013 Zhou R, Mohr S, Hannon GJ, Perrimon N. Inducing RNAi in Drosophila cells by transfection with dsRNA. Cold Spring Harbor Protocols. 2013: 461-3. PMID 23637371 DOI: 10.1101/Pdb.Prot074351  0.369
2013 Rajan A, Perrimon N. Of flies and men: insights on organismal metabolism from fruit flies. Bmc Biology. 11: 38. PMID 23587196 DOI: 10.1186/1741-7007-11-38  0.56
2013 Karpowicz P, Zhang Y, Hogenesch JB, Emery P, Perrimon N. The circadian clock gates the intestinal stem cell regenerative state. Cell Reports. 3: 996-1004. PMID 23583176 DOI: 10.1016/J.Celrep.2013.03.016  0.715
2013 Bergwitz C, Wee MJ, Sinha S, Huang J, DeRobertis C, Mensah LB, Cohen J, Friedman A, Kulkarni M, Hu Y, Vinayagam A, Schnall-Levin M, Berger B, Perkins LA, Mohr SE, ... Perrimon N, et al. Genetic determinants of phosphate response in Drosophila. Plos One. 8: e56753. PMID 23520455 DOI: 10.1371/Journal.Pone.0056753  0.588
2013 Vinayagam A, Hu Y, Kulkarni M, Roesel C, Sopko R, Mohr SE, Perrimon N. Protein complex-based analysis framework for high-throughput data sets. Science Signaling. 6: rs5. PMID 23443684 DOI: 10.1126/Scisignal.2003629  0.339
2013 Roti G, Carlton A, Ross KN, Markstein M, Pajcini K, Su AH, Perrimon N, Pear WS, Kung AL, Blacklow SC, Aster JC, Stegmaier K. Complementary genomic screens identify SERCA as a therapeutic target in NOTCH1 mutated cancer. Cancer Cell. 23: 390-405. PMID 23434461 DOI: 10.1016/J.Ccr.2013.01.015  0.784
2013 Pitsouli C, Perrimon N. The homeobox transcription factor cut coordinates patterning and growth during Drosophila airway remodeling. Science Signaling. 6: ra12. PMID 23423438 DOI: 10.1126/scisignal.2003424  0.801
2013 Yeh JT, Binari R, Gocha T, Dasgupta R, Perrimon N. PAPTi: a peptide aptamer interference toolkit for perturbation of protein-protein interaction networks. Scientific Reports. 3: 1156. PMID 23362456 DOI: 10.1038/Srep01156  0.332
2013 Staller MV, Yan D, Randklev S, Bragdon MD, Wunderlich ZB, Tao R, Perkins LA, Depace AH, Perrimon N. Depleting gene activities in early Drosophila embryos with the "maternal-Gal4-shRNA" system. Genetics. 193: 51-61. PMID 23105012 DOI: 10.1534/Genetics.112.144915  0.61
2013 Perrimon N. Abstract IA4: Synthetic lethal screens in Drosophila Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Pms-Ia4  0.397
2012 Rajan A, Perrimon N. Drosophila cytokine unpaired 2 regulates physiological homeostasis by remotely controlling insulin secretion. Cell. 151: 123-37. PMID 23021220 DOI: 10.1016/J.Cell.2012.08.019  0.558
2012 Stender JD, Pascual G, Liu W, Kaikkonen MU, Do K, Spann NJ, Boutros M, Perrimon N, Rosenfeld MG, Glass CK. Control of proinflammatory gene programs by regulated trimethylation and demethylation of histone H4K20. Molecular Cell. 48: 28-38. PMID 22921934 DOI: 10.1016/J.Molcel.2012.07.020  0.33
2012 Perrimon N, Pitsouli C, Shilo BZ. Signaling mechanisms controlling cell fate and embryonic patterning. Cold Spring Harbor Perspectives in Biology. 4: a005975. PMID 22855721 DOI: 10.1101/Cshperspect.A005975  0.804
2012 Kusche-Gullberg M, Nybakken K, Perrimon N, Lindahl U. Drosophila heparan sulfate, a novel design. The Journal of Biological Chemistry. 287: 21950-6. PMID 22556423 DOI: 10.1074/jbc.M112.350389  0.317
2012 Bergwitz C, Rasmussen MD, DeRobertis C, Wee MJ, Sinha S, Chen HH, Huang J, Perrimon N. Roles of major facilitator superfamily transporters in phosphate response in Drosophila. Plos One. 7: e31730. PMID 22359624 DOI: 10.1371/journal.pone.0031730  0.333
2012 Neumüller RA, Wirtz-Peitz F, Lee S, Kwon Y, Buckner M, Hoskins RA, Venken KJ, Bellen HJ, Mohr SE, Perrimon N. Stringent analysis of gene function and protein-protein interactions using fluorescently tagged genes. Genetics. 190: 931-40. PMID 22174071 DOI: 10.1534/Genetics.111.136465  0.795
2012 Mohr SE, Perrimon N. RNAi screening: new approaches, understandings, and organisms. Wiley Interdisciplinary Reviews. Rna. 3: 145-58. PMID 21953743 DOI: 10.1002/wrna.110  0.345
2011 Friedman AA, Tucker G, Singh R, Yan D, Vinayagam A, Hu Y, Binari R, Hong P, Sun X, Porto M, Pacifico S, Murali T, Finley RL, Asara JM, Berger B, ... Perrimon N, et al. Proteomic and functional genomic landscape of receptor tyrosine kinase and ras to extracellular signal-regulated kinase signaling. Science Signaling. 4: rs10. PMID 22028469 DOI: 10.1126/Scisignal.2002029  0.736
2011 Rohn JL, Sims D, Liu T, Fedorova M, Schöck F, Dopie J, Vartiainen MK, Kiger AA, Perrimon N, Baum B. Comparative RNAi screening identifies a conserved core metazoan actinome by phenotype. The Journal of Cell Biology. 194: 789-805. PMID 21893601 DOI: 10.1083/jcb.201103168  0.673
2011 Hu Y, Flockhart I, Vinayagam A, Bergwitz C, Berger B, Perrimon N, Mohr SE. An integrative approach to ortholog prediction for disease-focused and other functional studies. Bmc Bioinformatics. 12: 357. PMID 21880147 DOI: 10.1186/1471-2105-12-357  0.343
2011 Rajan A, Perrimon N. Drosophila as a model for interorgan communication: lessons from studies on energy homeostasis. Developmental Cell. 21: 29-31. PMID 21763605 DOI: 10.1016/J.Devcel.2011.06.034  0.556
2011 Ni JQ, Zhou R, Czech B, Liu LP, Holderbaum L, Yang-Zhou D, Shim HS, Tao R, Handler D, Karpowicz P, Binari R, Booker M, Brennecke J, Perkins LA, Hannon GJ, ... Perrimon N, et al. A genome-scale shRNA resource for transgenic RNAi in Drosophila. Nature Methods. 8: 405-7. PMID 21460824 DOI: 10.1038/Nmeth.1592  0.714
2011 Perrimon N, Zirin J, Bai J. Primary cell cultures from Drosophila gastrula embryos. Journal of Visualized Experiments : Jove. PMID 21403631 DOI: 10.3791/2215  0.731
2011 Chan WM, Tsoi H, Wu CC, Wong CH, Cheng TC, Li HY, Lau KF, Shaw PC, Perrimon N, Chan HY. Expanded polyglutamine domain possesses nuclear export activity which modulates subcellular localization and toxicity of polyQ disease protein via exportin-1. Human Molecular Genetics. 20: 1738-50. PMID 21300695 DOI: 10.1093/Hmg/Ddr049  0.321
2011 Gibson WT, Veldhuis JH, Rubinstein B, Cartwright HN, Perrimon N, Brodland GW, Nagpal R, Gibson MC. Control of the mitotic cleavage plane by local epithelial topology. Cell. 144: 427-38. PMID 21295702 DOI: 10.1016/J.Cell.2010.12.035  0.683
2011 Booker M, Samsonova AA, Kwon Y, Flockhart I, Mohr SE, Perrimon N. False negative rates in Drosophila cell-based RNAi screens: a case study. Bmc Genomics. 12: 50. PMID 21251254 DOI: 10.1186/1471-2164-12-50  0.459
2011 Kondo S, Perrimon N. A genome-wide RNAi screen identifies core components of the Gâ‚‚-M DNA damage checkpoint. Science Signaling. 4: rs1. PMID 21205937 DOI: 10.1126/scisignal.2001350  0.31
2011 Neumüller RA, Perrimon N. Where gene discovery turns into systems biology: genome-scale RNAi screens in Drosophila. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 3: 471-8. PMID 21197652 DOI: 10.1002/wsbm.127  0.365
2011 Graveley BR, Brooks AN, Carlson JW, Duff MO, Landolin JM, Yang L, Artieri CG, van Baren MJ, Boley N, Booth BW, Brown JB, Cherbas L, Davis CA, Dobin A, Li R, ... ... Perrimon N, et al. The developmental transcriptome of Drosophila melanogaster. Nature. 471: 473-9. PMID 21179090 DOI: 10.1038/Nature09715  0.518
2011 Cherbas L, Willingham A, Zhang D, Yang L, Zou Y, Eads BD, Carlson JW, Landolin JM, Kapranov P, Dumais J, Samsonova A, Choi JH, Roberts J, Davis CA, Tang H, ... ... Perrimon N, et al. The transcriptional diversity of 25 Drosophila cell lines. Genome Research. 21: 301-14. PMID 21177962 DOI: 10.1101/Gr.112961.110  0.368
2011 Micchelli CA, Sudmeier L, Perrimon N, Tang S, Beehler-Evans R. Identification of adult midgut precursors in Drosophila. Gene Expression Patterns : Gep. 11: 12-21. PMID 20804858 DOI: 10.1016/J.Gep.2010.08.005  0.587
2011 Roti G, Carlton A, Ross KN, Markstein M, Pajcini K, Perrimon N, Kung AL, Pear WS, Blacklow SC, Aster JC, Stegmaier K. Intersecting High-Throughput Screens Identifies SERCA As a Target for Modulating NOTCH1 In Hematopoietic Malignancies Blood. 118: 555-555. DOI: 10.1182/Blood.V118.21.555.555  0.402
2011 Yang X, Locasale J, Rahal R, Breitkopf S, VanderHeiden M, Spentzos D, Wu C, Perrimon N, Cantley L, Wong E, Asara J. Abstract LB-255: A mass spectrometry platform to quantitatively profile cancer cell metabolism from cells, tumors, and fixed tissue Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-255  0.322
2011 Friedman AA, Perrimon N, VanHook AM. Science Signaling Podcast: 25 October 2011 Science Signaling. 4: pc22-pc22. DOI: 10.1126/Scisignal.2002560  0.58
2011 Perrimon N. Deciphering Gene Expression Patterns Developmental Cell. 21: e1. DOI: 10.1016/j.devcel.2011.10.002  0.34
2010 Roy S, Ernst J, Kharchenko PV, Kheradpour P, Negre N, Eaton ML, Landolin JM, Bristow CA, Ma L, Lin MF, Washietl S, Arshinoff BI, Ay F, Meyer PE, ... ... Perrimon N, et al. Identification of functional elements and regulatory circuits by Drosophila modENCODE. Science (New York, N.Y.). 330: 1787-97. PMID 21177974 DOI: 10.1126/Science.1198374  0.681
2010 Karpowicz P, Perrimon N. All for one, and one for all: the clonality of the intestinal stem cell niche. F1000 Biology Reports. 2: 73. PMID 21173846 DOI: 10.3410/B2-73  0.719
2010 Rui Y, Bai J, Perrimon N. Sarcomere formation occurs by the assembly of multiple latent protein complexes. Plos Genetics. 6: e1001208. PMID 21124995 DOI: 10.1371/journal.pgen.1001208  0.314
2010 Karpowicz P, Perez J, Perrimon N. The Hippo tumor suppressor pathway regulates intestinal stem cell regeneration. Development (Cambridge, England). 137: 4135-45. PMID 21098564 DOI: 10.1242/dev.060483  0.735
2010 Pitsouli C, Perrimon N. Embryonic multipotent progenitors remodel the Drosophila airways during metamorphosis. Development (Cambridge, England). 137: 3615-24. PMID 20940225 DOI: 10.1242/dev.056408  0.794
2010 Zirin J, Perrimon N. Drosophila as a model system to study autophagy. Seminars in Immunopathology. 32: 363-72. PMID 20798940 DOI: 10.1007/S00281-010-0223-Y  0.731
2010 Yan H, Venkatesan K, Beaver JE, Klitgord N, Yildirim MA, Hao T, Hill DE, Cusick ME, Perrimon N, Roth FP, Vidal M. A genome-wide gene function prediction resource for Drosophila melanogaster. Plos One. 5: e12139. PMID 20711346 DOI: 10.1371/Journal.Pone.0012139  0.338
2010 Rajan A, Perrimon N. Steroids make you bigger? Fat chance says Myc. Cell Metabolism. 12: 7-9. PMID 20620990 DOI: 10.1016/J.Cmet.2010.06.003  0.534
2010 Kockel L, Kerr KS, Melnick M, Brückner K, Hebrok M, Perrimon N. Dynamic switch of negative feedback regulation in Drosophila Akt-TOR signaling. Plos Genetics. 6: e1000990. PMID 20585550 DOI: 10.1371/Journal.Pgen.1000990  0.804
2010 Perrimon N, Ni JQ, Perkins L. In vivo RNAi: today and tomorrow. Cold Spring Harbor Perspectives in Biology. 2: a003640. PMID 20534712 DOI: 10.1101/Cshperspect.A003640  0.347
2010 Bakal C, Perrimon N. Realizing the promise of RNAi high throughput screening. Developmental Cell. 18: 506-7. PMID 20412765 DOI: 10.1016/J.Devcel.2010.04.005  0.638
2010 Mohr S, Bakal C, Perrimon N. Genomic screening with RNAi: results and challenges. Annual Review of Biochemistry. 79: 37-64. PMID 20367032 DOI: 10.1146/Annurev-Biochem-060408-092949  0.672
2010 Nir O, Bakal C, Perrimon N, Berger B. Inference of RhoGAP/GTPase regulation using single-cell morphological data from a combinatorial RNAi screen. Genome Research. 20: 372-80. PMID 20144944 DOI: 10.1101/Gr.100248.109  0.674
2010 Zhang S, Binari R, Zhou R, Perrimon N. A genomewide RNA interference screen for modifiers of aggregates formation by mutant Huntingtin in Drosophila. Genetics. 184: 1165-79. PMID 20100940 DOI: 10.1534/Genetics.109.112516  0.366
2009 Yang X, Friedman A, Nagpal S, Perrimon N, Asara JM. Use of a label-free quantitative platform based on MS/MS average TIC to calculate dynamics of protein complexes in insulin signaling. Journal of Biomolecular Techniques : Jbt. 20: 272-7. PMID 19949701  0.444
2009 Apidianakis Y, Pitsouli C, Perrimon N, Rahme L. Synergy between bacterial infection and genetic predisposition in intestinal dysplasia. Proceedings of the National Academy of Sciences of the United States of America. 106: 20883-8. PMID 19934041 DOI: 10.1073/Pnas.0911797106  0.78
2009 Pitsouli C, Apidianakis Y, Perrimon N. Homeostasis in infected epithelia: stem cells take the lead. Cell Host & Microbe. 6: 301-7. PMID 19837370 DOI: 10.1016/J.Chom.2009.10.001  0.786
2009 Bai J, Sepp KJ, Perrimon N. Culture of Drosophila primary cells dissociated from gastrula embryos and their use in RNAi screening. Nature Protocols. 4: 1502-12. PMID 19798083 DOI: 10.1038/nprot.2009.147  0.369
2009 Kondo S, Booker M, Perrimon N. Cross-species RNAi rescue platform in Drosophila melanogaster. Genetics. 183: 1165-73. PMID 19720858 DOI: 10.1534/genetics.109.106567  0.366
2009 Vinegoni C, Razansky D, Pitsouli C, Perrimon N, Ntziachristos V, Weissleder R. Mesoscopic fluorescence tomography for in-vivo imaging of developing Drosophila. Journal of Visualized Experiments : Jove. PMID 19696720 DOI: 10.3791/1510  0.765
2009 Zhou R, Czech B, Brennecke J, Sachidanandam R, Wohlschlegel JA, Perrimon N, Hannon GJ. Processing of Drosophila endo-siRNAs depends on a specific Loquacious isoform. Rna (New York, N.Y.). 15: 1886-95. PMID 19635780 DOI: 10.1261/Rna.1611309  0.306
2009 Griffin R, Sustar A, Bonvin M, Binari R, del Valle Rodriguez A, Hohl AM, Bateman JR, Villalta C, Heffern E, Grunwald D, Bakal C, Desplan C, Schubiger G, Wu CT, Perrimon N. The twin spot generator for differential Drosophila lineage analysis. Nature Methods. 6: 600-2. PMID 19633664 DOI: 10.1038/Nmeth.1349  0.757
2009 Brouzes E, Medkova M, Savenelli N, Marran D, Twardowski M, Hutchison JB, Rothberg JM, Link DR, Perrimon N, Samuels ML. Droplet microfluidic technology for single-cell high-throughput screening. Proceedings of the National Academy of Sciences of the United States of America. 106: 14195-200. PMID 19617544 DOI: 10.1073/pnas.0903542106  0.313
2009 Kaplow IM, Singh R, Friedman A, Bakal C, Perrimon N, Berger B. RNAiCut: automated detection of significant genes from functional genomic screens. Nature Methods. 6: 476-7. PMID 19564846 DOI: 10.1038/Nmeth0709-476  0.722
2009 Ni JQ, Liu LP, Binari R, Hardy R, Shim HS, Cavallaro A, Booker M, Pfeiffer BD, Markstein M, Wang H, Villalta C, Laverty TR, Perkins LA, Perrimon N. A Drosophila resource of transgenic RNAi lines for neurogenetics. Genetics. 182: 1089-100. PMID 19487563 DOI: 10.1534/Genetics.109.103630  0.789
2009 Zhang S, Feany MB, Saraswati S, Littleton JT, Perrimon N. Inactivation of Drosophila Huntingtin affects long-term adult functioning and the pathogenesis of a Huntington's disease model. Disease Models & Mechanisms. 2: 247-66. PMID 19380309 DOI: 10.1242/Dmm.000653  0.306
2009 Demontis F, Perrimon N. Integration of Insulin receptor/Foxo signaling and dMyc activity during muscle growth regulates body size in Drosophila. Development (Cambridge, England). 136: 983-93. PMID 19211682 DOI: 10.1242/dev.027466  0.305
2009 Wang J, Zhou X, Li F, Bradley PL, Chang SF, Perrimon N, Wong ST. An image score inference system for RNAi genome-wide screening based on fuzzy mixture regression modeling. Journal of Biomedical Informatics. 42: 32-40. PMID 18547870 DOI: 10.1016/J.Jbi.2008.04.007  0.315
2008 Zhou R, Hotta I, Denli AM, Hong P, Perrimon N, Hannon GJ. Comparative analysis of argonaute-dependent small RNA pathways in Drosophila. Molecular Cell. 32: 592-9. PMID 19026789 DOI: 10.1016/J.Molcel.2008.10.018  0.322
2008 Bakal C, Linding R, Llense F, Heffern E, Martin-Blanco E, Pawson T, Perrimon N. Phosphorylation networks regulating JNK activity in diverse genetic backgrounds. Science (New York, N.Y.). 322: 453-6. PMID 18927396 DOI: 10.1126/Science.1158739  0.665
2008 Pitsouli C, Perrimon N. Developmental biology: Our fly cousins' gut. Nature. 454: 592-3. PMID 18668098 DOI: 10.1038/454592a  0.775
2008 Vincent S, Perrimon N, Axelrod JD. Hedgehog and Wingless stabilize but do not induce cell fate during Drosophila dorsal embryonic epidermal patterning. Development (Cambridge, England). 135: 2767-75. PMID 18614578 DOI: 10.1242/Dev.017814  0.791
2008 Sepp KJ, Hong P, Lizarraga SB, Liu JS, Mejia LA, Walsh CA, Perrimon N. Identification of neural outgrowth genes using genome-wide RNAi. Plos Genetics. 4: e1000111. PMID 18604272 DOI: 10.1371/Journal.Pgen.1000111  0.398
2008 Yin Z, Zhou X, Bakal C, Li F, Sun Y, Perrimon N, Wong ST. Using iterative cluster merging with improved gap statistics to perform online phenotype discovery in the context of high-throughput RNAi screens. Bmc Bioinformatics. 9: 264. PMID 18534020 DOI: 10.1186/1471-2105-9-264  0.659
2008 Bai J, Binari R, Ni JQ, Vijayakanthan M, Li HS, Perrimon N. RNA interference screening in Drosophila primary cells for genes involved in muscle assembly and maintenance. Development (Cambridge, England). 135: 1439-49. PMID 18359903 DOI: 10.1242/Dev.012849  0.364
2008 Markstein M, Pitsouli C, Villalta C, Celniker SE, Perrimon N. Exploiting position effects and the gypsy retrovirus insulator to engineer precisely expressed transgenes. Nature Genetics. 40: 476-83. PMID 18311141 DOI: 10.1038/ng.101  0.789
2008 Philips JA, Porto MC, Wang H, Rubin EJ, Perrimon N. ESCRT factors restrict mycobacterial growth. Proceedings of the National Academy of Sciences of the United States of America. 105: 3070-5. PMID 18287038 DOI: 10.1073/Pnas.0707206105  0.303
2008 Wang J, Zhou X, Bradley PL, Chang SF, Perrimon N, Wong ST. Cellular phenotype recognition for high-content RNA interference genome-wide screening. Journal of Biomolecular Screening. 13: 29-39. PMID 18227224 DOI: 10.1177/1087057107311223  0.405
2008 Ni JQ, Markstein M, Binari R, Pfeiffer B, Liu LP, Villalta C, Booker M, Perkins L, Perrimon N. Vector and parameters for targeted transgenic RNA interference in Drosophila melanogaster. Nature Methods. 5: 49-51. PMID 18084299 DOI: 10.1038/Nmeth1146  0.774
2008 Vinegoni C, Pitsouli C, Razansky D, Perrimon N, Ntziachristos V. In vivo imaging of Drosophila melanogaster pupae with mesoscopic fluorescence tomography. Nature Methods. 5: 45-7. PMID 18066071 DOI: 10.1038/Nmeth1149  0.763
2008 Baym M, Bakal C, Perrimon N, Berger B. High-resolution modeling of cellular signaling networks Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 4955: 257-271. DOI: 10.1007/978-3-540-78839-3_22  0.587
2007 Perrimon N, Mathey-Prevot B. Matter arising: off-targets and genome-scale RNAi screens in Drosophila. Fly. 1: 1-5. PMID 18705022 DOI: 10.4161/Fly.3601  0.319
2007 Bai J, Hartwig JH, Perrimon N. SALS, a WH2-domain-containing protein, promotes sarcomeric actin filament elongation from pointed ends during Drosophila muscle growth. Developmental Cell. 13: 828-42. PMID 18061565 DOI: 10.1016/j.devcel.2007.10.003  0.312
2007 Leopold P, Perrimon N. Drosophila and the genetics of the internal milieu. Nature. 450: 186-8. PMID 17994083 DOI: 10.1038/nature06286  0.313
2007 DasGupta R, Nybakken K, Booker M, Mathey-Prevot B, Gonsalves F, Changkakoty B, Perrimon N. A case study of the reproducibility of transcriptional reporter cell-based RNAi screens in Drosophila. Genome Biology. 8: R203. PMID 17903264 DOI: 10.1186/Gb-2007-8-9-R203  0.364
2007 Ramadan N, Flockhart I, Booker M, Perrimon N, Mathey-Prevot B. Design and implementation of high-throughput RNAi screens in cultured Drosophila cells. Nature Protocols. 2: 2245-64. PMID 17853882 DOI: 10.1038/nprot.2007.250  0.316
2007 Bakal C, Aach J, Church G, Perrimon N. Quantitative morphological signatures define local signaling networks regulating cell morphology. Science (New York, N.Y.). 316: 1753-6. PMID 17588932 DOI: 10.1126/Science.1140324  0.691
2007 Lu J, Ruhf ML, Perrimon N, Leder P. A genome-wide RNA interference screen identifies putative chromatin regulators essential for E2F repression. Proceedings of the National Academy of Sciences of the United States of America. 104: 9381-6. PMID 17517653 DOI: 10.1073/Pnas.0610279104  0.419
2007 Friedman A, Perrimon N. Genetic screening for signal transduction in the era of network biology. Cell. 128: 225-31. PMID 17254958 DOI: 10.1016/J.Cell.2007.01.007  0.585
2007 Perrimon N, Mathey-Prevot B. Applications of high-throughput RNA interference screens to problems in cell and developmental biology. Genetics. 175: 7-16. PMID 17244760 DOI: 10.1534/genetics.106.069963  0.36
2007 Perrimon N, Friedman A, Mathey-Prevot B, Eggert US. Drug-target identification in Drosophila cells: combining high-throughout RNAi and small-molecule screens. Drug Discovery Today. 12: 28-33. PMID 17198970 DOI: 10.1016/J.Drudis.2006.10.006  0.542
2007 Bach EA, Ekas LA, Ayala-Camargo A, Flaherty MS, Lee H, Perrimon N, Baeg GH. GFP reporters detect the activation of the Drosophila JAK/STAT pathway in vivo. Gene Expression Patterns : Gep. 7: 323-31. PMID 17008134 DOI: 10.1016/j.modgep.2006.08.003  0.609
2007 Yin Z, Zhou X, Bakal C, Li F, Sun Y, Perrimon N, Wong STC. Online phenotype discovery in high-content RNAi screens using gap statistics Aip Conference Proceedings. 952: 86-95. DOI: 10.1063/1.2816647  0.591
2006 Mathey-Prevot B, Perrimon N. Drosophila genome-wide RNAi screens: are they delivering the promise? Cold Spring Harbor Symposia On Quantitative Biology. 71: 141-8. PMID 17381290 DOI: 10.1101/sqb.2006.71.027  0.349
2006 Friedman A, Perrimon N. A functional RNAi screen for regulators of receptor tyrosine kinase and ERK signalling. Nature. 444: 230-4. PMID 17086199 DOI: 10.1038/Nature05280  0.621
2006 Cherry S, Kunte A, Wang H, Coyne C, Rawson RB, Perrimon N. COPI activity coupled with fatty acid biosynthesis is required for viral replication. Plos Pathogens. 2: e102. PMID 17040126 DOI: 10.1371/Journal.Ppat.0020102  0.55
2006 Echeverri CJ, Beachy PA, Baum B, Boutros M, Buchholz F, Chanda SK, Downward J, Ellenberg J, Fraser AG, Hacohen N, Hahn WC, Jackson AL, Kiger A, Linsley PS, Lum L, ... ... Perrimon N, et al. Minimizing the risk of reporting false positives in large-scale RNAi screens. Nature Methods. 3: 777-9. PMID 16990807 DOI: 10.1038/Nmeth1006-777  0.623
2006 Kulkarni MM, Booker M, Silver SJ, Friedman A, Hong P, Perrimon N, Mathey-Prevot B. Evidence of off-target effects associated with long dsRNAs in Drosophila melanogaster cell-based assays. Nature Methods. 3: 833-8. PMID 16964256 DOI: 10.1038/Nmeth935  0.569
2006 Gibson MC, Patel AB, Nagpal R, Perrimon N. The emergence of geometric order in proliferating metazoan epithelia. Nature. 442: 1038-41. PMID 16900102 DOI: 10.1038/Nature05014  0.603
2006 Friedman A, Perrimon N. High-throughput approaches to dissecting MAPK signaling pathways. Methods (San Diego, Calif.). 40: 262-71. PMID 16844385 DOI: 10.1016/J.Ymeth.2006.05.002  0.604
2006 Chen LY, Wang JC, Hyvert Y, Lin HP, Perrimon N, Imler JL, Hsu JC. Weckle is a zinc finger adaptor of the toll pathway in dorsoventral patterning of the Drosophila embryo. Current Biology : Cb. 16: 1183-93. PMID 16782008 DOI: 10.1016/j.cub.2006.05.050  0.35
2006 Echeverri CJ, Perrimon N. High-throughput RNAi screening in cultured cells: a user's guide. Nature Reviews. Genetics. 7: 373-84. PMID 16607398 DOI: 10.1038/nrg1836  0.307
2006 Bard F, Casano L, Mallabiabarrena A, Wallace E, Saito K, Kitayama H, Guizzunti G, Hu Y, Wendler F, Dasgupta R, Perrimon N, Malhotra V. Functional genomics reveals genes involved in protein secretion and Golgi organization. Nature. 439: 604-7. PMID 16452979 DOI: 10.1038/Nature04377  0.372
2006 Flockhart I, Booker M, Kiger A, Boutros M, Armknecht S, Ramadan N, Richardson K, Xu A, Perrimon N, Mathey-Prevot B. FlyRNAi: the Drosophila RNAi screening center database. Nucleic Acids Research. 34: D489-94. PMID 16381918 DOI: 10.1093/Nar/Gkj114  0.651
2006 Micchelli CA, Perrimon N. Evidence that stem cells reside in the adult Drosophila midgut epithelium. Nature. 439: 475-9. PMID 16340959 DOI: 10.1038/Nature04371  0.624
2006 Karsten P, Plischke I, Perrimon N, Zeidler MP. Mutational analysis reveals separable DNA binding and trans-activation of Drosophila STAT92E. Cellular Signalling. 18: 819-29. PMID 16129580 DOI: 10.1016/j.cellsig.2005.07.006  0.335
2005 Nybakken K, Vokes SA, Lin TY, McMahon AP, Perrimon N. A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway. Nature Genetics. 37: 1323-32. PMID 16311596 DOI: 10.1038/Ng1682  0.404
2005 Kirilly D, Spana EP, Perrimon N, Padgett RW, Xie T. BMP signaling is required for controlling somatic stem cell self-renewal in the Drosophila ovary. Developmental Cell. 9: 651-62. PMID 16256740 DOI: 10.1016/j.devcel.2005.09.013  0.732
2005 Häcker U, Nybakken K, Perrimon N. Heparan sulphate proteoglycans: the sweet side of development. Nature Reviews. Molecular Cell Biology. 6: 530-41. PMID 16072037 DOI: 10.1038/nrm1681  0.658
2005 Baeg GH, Zhou R, Perrimon N. Genome-wide RNAi analysis of JAK/STAT signaling components in Drosophila. Genes & Development. 19: 1861-70. PMID 16055650 DOI: 10.1101/gad.1320705  0.386
2005 Agaisse H, Burrack LS, Philips JA, Rubin EJ, Perrimon N, Higgins DE. Genome-wide RNAi screen for host factors required for intracellular bacterial infection. Science (New York, N.Y.). 309: 1248-51. PMID 16020693 DOI: 10.1126/Science.1116008  0.306
2005 Schober M, Rebay I, Perrimon N. Function of the ETS transcription factor Yan in border cell migration. Development (Cambridge, England). 132: 3493-504. PMID 16014514 DOI: 10.1242/Dev.01911  0.388
2005 DasGupta R, Boutros M, Perrimon N. Drosophila Wnt/Fz pathways. Science's Stke : Signal Transduction Knowledge Environment. 2005: cm5. PMID 15886387 DOI: 10.1126/Stke.2832005Cm5  0.403
2005 DasGupta R, Kaykas A, Moon RT, Perrimon N. Functional genomic analysis of the Wnt-wingless signaling pathway. Science (New York, N.Y.). 308: 826-33. PMID 15817814 DOI: 10.1126/Science.1109374  0.431
2005 Gibson MC, Perrimon N. Extrusion and death of DPP/BMP-compromised epithelial cells in the developing Drosophila wing. Science (New York, N.Y.). 307: 1785-9. PMID 15774762 DOI: 10.1126/Science.1104751  0.626
2005 Hayward P, Brennan K, Sanders P, Balayo T, DasGupta R, Perrimon N, Martinez Arias A. Notch modulates Wnt signalling by associating with Armadillo/beta-catenin and regulating its transcriptional activity. Development (Cambridge, England). 132: 1819-30. PMID 15772135 DOI: 10.1242/Dev.01724  0.399
2005 Cherry S, Doukas T, Armknecht S, Whelan S, Wang H, Sarnow P, Perrimon N. Genome-wide RNAi screen reveals a specific sensitivity of IRES-containing RNA viruses to host translation inhibition. Genes & Development. 19: 445-52. PMID 15713840 DOI: 10.1101/Gad.1267905  0.541
2005 Armknecht S, Boutros M, Kiger A, Nybakken K, Mathey-Prevot B, Perrimon N. High-throughput RNA interference screens in Drosophila tissue culture cells. Methods in Enzymology. 392: 55-73. PMID 15644175 DOI: 10.1016/S0076-6879(04)92004-6  0.661
2004 Eggert US, Kiger AA, Richter C, Perlman ZE, Perrimon N, Mitchison TJ, Field CM. Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets. Plos Biology. 2: e379. PMID 15547975 DOI: 10.1371/Journal.Pbio.0020379  0.674
2004 Baeg GH, Selva EM, Goodman RM, Dasgupta R, Perrimon N. The Wingless morphogen gradient is established by the cooperative action of Frizzled and Heparan Sulfate Proteoglycan receptors. Developmental Biology. 276: 89-100. PMID 15531366 DOI: 10.1016/J.Ydbio.2004.08.023  0.362
2004 Dasgupta R, Perrimon N. Using RNAi to catch Drosophila genes in a web of interactions: insights into cancer research. Oncogene. 23: 8359-65. PMID 15517017 DOI: 10.1038/Sj.Onc.1208028  0.359
2004 Schlesinger A, Kiger A, Perrimon N, Shilo BZ. Small wing PLCgamma is required for ER retention of cleaved Spitz during eye development in Drosophila. Developmental Cell. 7: 535-45. PMID 15469842 DOI: 10.1016/j.devcel.2004.09.001  0.664
2004 Friedman A, Perrimon N. Genome-wide high-throughput screens in functional genomics. Current Opinion in Genetics & Development. 14: 470-6. PMID 15380236 DOI: 10.1016/J.Gde.2004.07.010  0.585
2004 Sinenko SA, Kim EK, Wynn R, Manfruelli P, Ando I, Wharton KA, Perrimon N, Mathey-Prevot B. Yantar, a conserved arginine-rich protein is involved in Drosophila hemocyte development. Developmental Biology. 273: 48-62. PMID 15302597 DOI: 10.1016/J.Ydbio.2004.05.022  0.384
2004 Brückner K, Kockel L, Duchek P, Luque CM, Rørth P, Perrimon N. The PDGF/VEGF receptor controls blood cell survival in Drosophila. Developmental Cell. 7: 73-84. PMID 15239955 DOI: 10.1016/j.devcel.2004.06.007  0.347
2004 Agaisse H, Perrimon N. The roles of JAK/STAT signaling in Drosophila immune responses. Immunological Reviews. 198: 72-82. PMID 15199955 DOI: 10.1111/J.0105-2896.2004.0133.X  0.324
2004 Zeidler MP, Tan C, Bellaiche Y, Cherry S, Häder S, Gayko U, Perrimon N. Temperature-sensitive control of protein activity by conditionally splicing inteins. Nature Biotechnology. 22: 871-6. PMID 15184905 DOI: 10.1038/Nbt979  0.749
2004 Perrimon N, Häcker U. Wingless, hedgehog and heparan sulfate proteoglycans. Development (Cambridge, England). 131: 2509-11; author repl. PMID 15148297 DOI: 10.1242/dev.01225  0.636
2004 Boutros M, Kiger AA, Armknecht S, Kerr K, Hild M, Koch B, Haas SA, Paro R, Perrimon N. Genome-wide RNAi analysis of growth and viability in Drosophila cells. Science (New York, N.Y.). 303: 832-5. PMID 14764878 DOI: 10.1126/science.1091266  0.696
2004 Cherry S, Perrimon N. Entry is a rate-limiting step for viral infection in a Drosophila melanogaster model of pathogenesis. Nature Immunology. 5: 81-7. PMID 14691479 DOI: 10.1038/Ni1019  0.531
2003 Bach EA, Vincent S, Zeidler MP, Perrimon N. A sensitized genetic screen to identify novel regulators and components of the Drosophila janus kinase/signal transducer and activator of transcription pathway. Genetics. 165: 1149-66. PMID 14668372  0.71
2003 Gibson MC, Perrimon N. Apicobasal polarization: epithelial form and function. Current Opinion in Cell Biology. 15: 747-52. PMID 14644201 DOI: 10.1016/J.Ceb.2003.10.008  0.587
2003 Kiger AA, Baum B, Jones S, Jones MR, Coulson A, Echeverri C, Perrimon N. A functional genomic analysis of cell morphology using RNA interference. Journal of Biology. 2: 27. PMID 14527345 DOI: 10.1186/1475-4924-2-27  0.71
2003 Agaisse H, Petersen UM, Boutros M, Mathey-Prevot B, Perrimon N. Signaling role of hemocytes in Drosophila JAK/STAT-dependent response to septic injury. Developmental Cell. 5: 441-50. PMID 12967563 DOI: 10.1016/S1534-5807(03)00244-2  0.345
2003 Sasamura T, Sasaki N, Miyashita F, Nakao S, Ishikawa HO, Ito M, Kitagawa M, Harigaya K, Spana E, Bilder D, Perrimon N, Matsuno K. neurotic, a novel maternal neurogenic gene, encodes an O-fucosyltransferase that is essential for Notch-Delta interactions. Development (Cambridge, England). 130: 4785-95. PMID 12917292 DOI: 10.1242/Dev.00679  0.808
2003 Ghiglione C, Amundadottir L, Andresdottir M, Bilder D, Diamonti JA, Noselli S, Perrimon N, Carraway III KL. Mechanism of inhibition of the Drosophila and mammalian EGF receptors by the transmembrane protein Kekkon 1. Development (Cambridge, England). 130: 4483-93. PMID 12900463 DOI: 10.1242/Dev.00617  0.625
2003 Lüders F, Segawa H, Stein D, Selva EM, Perrimon N, Turco SJ, Häcker U. Slalom encodes an adenosine 3'-phosphate 5'-phosphosulfate transporter essential for development in Drosophila. The Embo Journal. 22: 3635-44. PMID 12853478 DOI: 10.1093/Emboj/Cdg345  0.645
2003 Bashirullah A, Pasquinelli AE, Kiger AA, Perrimon N, Ruvkun G, Thummel CS. Coordinate regulation of small temporal RNAs at the onset of Drosophila metamorphosis. Developmental Biology. 259: 1-8. PMID 12812783 DOI: 10.1016/S0012-1606(03)00063-0  0.642
2003 Adám G, Perrimon N, Noselli S. The retinoic-like juvenile hormone controls the looping of left-right asymmetric organs in Drosophila. Development (Cambridge, England). 130: 2397-406. PMID 12702654 DOI: 10.1242/Dev.00460  0.315
2003 Schöck F, Perrimon N. Retraction of the Drosophila germ band requires cell-matrix interaction. Genes & Development. 17: 597-602. PMID 12629042 DOI: 10.1101/gad.1068403  0.3
2003 Bilder D, Schober M, Perrimon N. Integrated activity of PDZ protein complexes regulates epithelial polarity. Nature Cell Biology. 5: 53-8. PMID 12510194 DOI: 10.1038/ncb897  0.621
2003 Tan C, Stronach B, Perrimon N. Roles of myosin phosphatase during Drosophila development. Development (Cambridge, England). 130: 671-81. PMID 12505998 DOI: 10.1242/Dev.00298  0.755
2003 Micchelli CA, Esler WP, Kimberly WT, Jack C, Berezovska O, Kornilova A, Hyman BT, Perrimon N, Wolfe MS. Gamma-secretase/presenilin inhibitors for Alzheimer's disease phenocopy Notch mutations in Drosophila. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 79-81. PMID 12424225 DOI: 10.1096/Fj.02-0394Fje  0.574
2003 Stronach BE, Perrimon N. Developmental Signaling: JNK Pathway in Drosophila Morphogenesis Handbook of Cell Signaling. 2: 783-787. DOI: 10.1016/B978-012124546-7/50612-4  0.711
2002 Lin X, Perrimon N. Developmental roles of heparan sulfate proteoglycans in Drosophila. Glycoconjugate Journal. 19: 363-8. PMID 12975617 DOI: 10.1023/A:1025329323438  0.681
2002 Song HJ, Billeter JC, Reynaud E, Carlo T, Spana EP, Perrimon N, Goodwin SF, Baker BS, Taylor BJ. The fruitless gene is required for the proper formation of axonal tracts in the embryonic central nervous system of Drosophila. Genetics. 162: 1703-24. PMID 12524343  0.706
2002 Hou SX, Zheng Z, Chen X, Perrimon N. The Jak/STAT pathway in model organisms: emerging roles in cell movement. Developmental Cell. 3: 765-78. PMID 12479803 DOI: 10.1016/S1534-5807(02)00376-3  0.382
2002 Wills Z, Emerson M, Rusch J, Bikoff J, Baum B, Perrimon N, Van Vactor D. A Drosophila homolog of cyclase-associated proteins collaborates with the Abl tyrosine kinase to control midline axon pathfinding. Neuron. 36: 611-22. PMID 12441051 DOI: 10.1016/S0896-6273(02)01022-X  0.361
2002 Boutros M, Agaisse H, Perrimon N. Sequential activation of signaling pathways during innate immune responses in Drosophila. Developmental Cell. 3: 711-22. PMID 12431377 DOI: 10.1016/S1534-5807(02)00325-8  0.345
2002 Nybakken K, Perrimon N. Heparan sulfate proteoglycan modulation of developmental signaling in Drosophila. Biochimica Et Biophysica Acta. 1573: 280-91. PMID 12417410 DOI: 10.1016/S0304-4165(02)00395-1  0.348
2002 Hrdlicka L, Gibson M, Kiger A, Micchelli C, Schober M, Schöck F, Perrimon N. Analysis of twenty-four Gal4 lines in Drosophila melanogaster. Genesis (New York, N.Y. : 2000). 34: 51-7. PMID 12324947 DOI: 10.1002/Gene.10125  0.786
2002 Schober M, Perrimon N. Unconventional ways to travel. Nature Cell Biology. 4: E211-2. PMID 12205482 DOI: 10.1038/ncb0902-e211  0.346
2002 Nybakken K, Perrimon N. Hedgehog signal transduction: recent findings. Current Opinion in Genetics & Development. 12: 503-11. PMID 12200154 DOI: 10.1016/S0959-437X(02)00333-7  0.36
2002 Li WX, Agaisse H, Mathey-Prevot B, Perrimon N. Differential requirement for STAT by gain-of-function and wild-type receptor tyrosine kinase Torso in Drosophila. Development (Cambridge, England). 129: 4241-8. PMID 12183376  0.658
2002 Schock F, Perrimon N. Molecular mechanisms of epithelial morphogenesis. Annual Review of Cell and Developmental Biology. 18: 463-93. PMID 12142280 DOI: 10.1146/annurev.cellbio.18.022602.131838  0.708
2002 Moon RT, Bowerman B, Boutros M, Perrimon N. The promise and perils of Wnt signaling through beta-catenin. Science (New York, N.Y.). 296: 1644-6. PMID 12040179 DOI: 10.1126/science.1071549  0.346
2002 Mathew D, Gramates LS, Packard M, Thomas U, Bilder D, Perrimon N, Gorczyca M, Budnik V. Recruitment of scribble to the synaptic scaffolding complex requires GUK-holder, a novel DLG binding protein. Current Biology : Cb. 12: 531-9. PMID 11937021 DOI: 10.1016/S0960-9822(02)00758-3  0.596
2002 Chen HW, Marinissen MJ, Oh SW, Chen X, Melnick M, Perrimon N, Gutkind JS, Hou SX. CKA, a novel multidomain protein, regulates the JUN N-terminal kinase signal transduction pathway in Drosophila. Molecular and Cellular Biology. 22: 1792-803. PMID 11865058 DOI: 10.1128/MCB.22.6.1792-1803.2002  0.385
2002 Micchelli CA, The I, Selva E, Mogila V, Perrimon N. Rasp, a putative transmembrane acyltransferase, is required for Hedgehog signaling. Development (Cambridge, England). 129: 843-51. PMID 11861468  0.59
2002 Stronach B, Perrimon N. Activation of the JNK pathway during dorsal closure in Drosophila requires the mixed lineage kinase, slipper. Genes & Development. 16: 377-87. PMID 11825878 DOI: 10.1101/Gad.953002  0.744
2002 Ghiglione C, Bach EA, Paraiso Y, Carraway KL, Noselli S, Perrimon N. Mechanism of activation of the Drosophila EGF Receptor by the TGFalpha ligand Gurken during oogenesis. Development (Cambridge, England). 129: 175-86. PMID 11782411  0.525
2001 Hong Y, Stronach B, Perrimon N, Jan LY, Jan YN. Drosophila Stardust interacts with Crumbs to control polarity of epithelia but not neuroblasts. Nature. 414: 634-8. PMID 11740559 DOI: 10.1038/414634A  0.74
2001 Selva EM, Perrimon N. Role of heparan sulfate proteoglycans in cell signaling and cancer. Advances in Cancer Research. 83: 67-80. PMID 11665721 DOI: 10.1016/S0065-230X(01)83003-7  0.375
2001 Baum B, Perrimon N. Spatial control of the actin cytoskeleton in Drosophila epithelial cells. Nature Cell Biology. 3: 883-90. PMID 11584269 DOI: 10.1038/ncb1001-883  0.33
2001 Suzanne M, Perrimon N, Noselli S. The Drosophila JNK pathway controls the morphogenesis of the egg dorsal appendages and micropyle. Developmental Biology. 237: 282-94. PMID 11543614 DOI: 10.1006/dbio.2001.0384  0.39
2001 Selva EM, Hong K, Baeg GH, Beverley SM, Turco SJ, Perrimon N, Häcker U. Dual role of the fringe connection gene in both heparan sulphate and fringe-dependent signalling events. Nature Cell Biology. 3: 809-15. PMID 11533660 DOI: 10.1038/Ncb0901-809  0.659
2001 Stronach BE, Perrimon N. Investigation of leading edge formation at the interface of amnioserosa and dorsal ectoderm in the Drosophila embryo. Development (Cambridge, England). 128: 2905-13. PMID 11532914  0.727
2001 Vincent S, Perkins LA, Perrimon N. Doublesex surprises. Cell. 106: 399-402. PMID 11525726 DOI: 10.1016/S0092-8674(01)00468-8  0.527
2001 Vincent S, Perrimon N. Developmental biology. Fishing for morphogens. Nature. 411: 533, 535-6. PMID 11385549 DOI: 10.1038/35079214  0.627
2001 Baeg GH, Lin X, Khare N, Baumgartner S, Perrimon N. Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless. Development (Cambridge, England). 128: 87-94. PMID 11092814 DOI: 10.1042/Bst029A010C  0.393
2001 Bilder D, Birnbaum D, Borg J, Huibregtse J, Kennedy M, Labouesse M, Mechler B, Perrimon N. Response to “Problems with LAP nomenclature” Nature Cell Biology. 3: E90-E90. DOI: 10.1038/35070149  0.564
2000 Noselli S, Perrimon N. Signal transduction. Are there close encounters between signaling pathways? Science (New York, N.Y.). 290: 68-9. PMID 11183153 DOI: 10.1126/SCIENCE.290.5489.68  0.362
2000 Zeidler MP, Perrimon N, Strutt DI. Multiple roles for four-jointed in planar polarity and limb patterning. Developmental Biology. 228: 181-96. PMID 11112323 DOI: 10.1006/dbio.2000.9940  0.331
2000 Noll E, Medina M, Hartley D, Zhou J, Perrimon N, Kosik KS. Presenilin affects arm/beta-catenin localization and function in Drosophila. Developmental Biology. 227: 450-64. PMID 11071766 DOI: 10.1006/dbio.2000.9925  0.335
2000 Zeidler MP, Perrimon N. Sex determination: co-opted signals determine gender. Current Biology : Cb. 10: R682-4. PMID 10996811 DOI: 10.1016/S0960-9822(00)00686-2  0.32
2000 Baum B, Li W, Perrimon N. A cyclase-associated protein regulates actin and cell polarity during Drosophila oogenesis and in yeast. Current Biology : Cb. 10: 964-73. PMID 10985383 DOI: 10.1016/S0960-9822(00)00640-0  0.686
2000 Baeg GH, Perrimon N. Functional binding of secreted molecules to heparan sulfate proteoglycans in Drosophila. Current Opinion in Cell Biology. 12: 575-80. PMID 10978892 DOI: 10.1016/S0955-0674(00)00134-4  0.351
2000 Lin X, Perrimon N. Role of heparan sulfate proteoglycans in cell-cell signaling in Drosophila. Matrix Biology : Journal of the International Society For Matrix Biology. 19: 303-7. PMID 10963990 DOI: 10.1016/S0945-053X(00)00073-1  0.379
2000 Bilder D, Li M, Perrimon N. Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors. Science (New York, N.Y.). 289: 113-6. PMID 10884224 DOI: 10.1126/science.289.5476.113  0.643
2000 Bilder D, Birnbaum D, Borg JP, Bryant P, Huigbretse J, Jansen E, Kennedy MB, Labouesse M, Legouis R, Mechler B, Perrimon N, Petit M, Sinha P. Collective nomenclature for LAP proteins. Nature Cell Biology. 2: E114. PMID 10878817 DOI: 10.1038/35017119  0.586
2000 Tanaka K, Okabayashi K, Asashima M, Perrimon N, Kadowaki T. The evolutionarily conserved porcupine gene family is involved in the processing of the Wnt family. European Journal of Biochemistry / Febs. 267: 4300-11. PMID 10866835 DOI: 10.1046/J.1432-1033.2000.01478.X  0.365
2000 Zeidler MP, Bach EA, Perrimon N. The roles of the Drosophila JAK/STAT pathway. Oncogene. 19: 2598-606. PMID 10851058 DOI: 10.1038/sj.onc.1203482  0.625
2000 The I, Perrimon N. Morphogen diffusion: the case of the wingless protein. Nature Cell Biology. 2: E79-82. PMID 10806491 DOI: 10.1038/35010511  0.304
2000 Perrimon N, Bernfield M. Specificities of heparan sulphate proteoglycans in developmental processes. Nature. 404: 725-8. PMID 10783877 DOI: 10.1038/35008000  0.352
2000 Bilder D, Perrimon N. Localization of apical epithelial determinants by the basolateral PDZ protein Scribble. Nature. 403: 676-80. PMID 10688207 DOI: 10.1038/35001108  0.634
1999 Zeidler MP, Perrimon N, Strutt DI. The four-jointed gene is required in the Drosophila eye for ommatidial polarity specification. Current Biology : Cb. 9: 1363-72. PMID 10607560 DOI: 10.1016/S0960-9822(00)80081-0  0.346
1999 Stronach BE, Perrimon N. Stress signaling in Drosophila. Oncogene. 18: 6172-82. PMID 10557109 DOI: 10.1038/Sj.Onc.1203125  0.749
1999 The I, Bellaiche Y, Perrimon N. Hedgehog movement is regulated through tout velu-dependent synthesis of a heparan sulfate proteoglycan. Molecular Cell. 4: 633-9. PMID 10549295 DOI: 10.1016/S1097-2765(00)80214-2  0.673
1999 Spana E, Perrimon N. The latest in signal transduction, 1999. Specificity in Signal Transduction, Keystone, Colorado, USA, 9-14 April 1999. Trends in Genetics : Tig. 15: 301-2. PMID 10475855 DOI: 10.1016/S0168-9525(99)01791-6  0.717
1999 Mogila VA, Bellaiche Y, Perrimon N. Expression of I-Sce I in Drosophila to induce DNA double-strand breaks. Methods in Molecular Biology (Clifton, N.J.). 113: 439-45. PMID 10443440 DOI: 10.1385/1-59259-675-4:439  0.596
1999 Lin X, Perrimon N. Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signalling. Nature. 400: 281-4. PMID 10421372 DOI: 10.1038/22343  0.677
1999 Bellaiche Y, Mogila V, Perrimon N. I-SceI endonuclease, a new tool for studying DNA double-strand break repair mechanisms in Drosophila. Genetics. 152: 1037-44. PMID 10388822  0.619
1999 Zeidler MP, Perrimon N, Strutt DI. Polarity determination in the Drosophila eye: a novel role for unpaired and JAK/STAT signaling. Genes & Development. 13: 1342-53. PMID 10346822 DOI: 10.1101/Gad.13.10.1342  0.316
1999 Perrimon N, McMahon AP. Negative feedback mechanisms and their roles during pattern formation. Cell. 97: 13-6. PMID 10199398 DOI: 10.1016/S0092-8674(00)80710-2  0.366
1999 Ghiglione C, Perrimon N, Perkins LA. Quantitative variations in the level of MAPK activity control patterning of the embryonic termini in Drosophila. Developmental Biology. 205: 181-93. PMID 9882506 DOI: 10.1006/Dbio.1998.9102  0.378
1998 Cleghon V, Feldmann P, Ghiglione C, Copeland TD, Perrimon N, Hughes DA, Morrison DK. Opposing actions of CSW and RasGAP modulate the strength of Torso RTK signaling in the Drosophila terminal pathway. Molecular Cell. 2: 719-27. PMID 9885560 DOI: 10.1016/S1097-2765(00)80287-7  0.342
1998 Shulman JM, Perrimon N, Axelrod JD. Frizzled signaling and the developmental control of cell polarity. Trends in Genetics : Tig. 14: 452-8. PMID 9825673 DOI: 10.1016/S0168-9525(98)01584-4  0.708
1998 Perrimon N, Duffy JB. Developmental biology. Sending all the right signals. Nature. 396: 18-9. PMID 9817197 DOI: 10.1038/23815  0.307
1998 Harrison DA, McCoon PE, Binari R, Gilman M, Perrimon N. Drosophila unpaired encodes a secreted protein that activates the JAK signaling pathway. Genes & Development. 12: 3252-63. PMID 9784499 DOI: 10.1101/Gad.12.20.3252  0.614
1998 Axelrod JD, Miller JR, Shulman JM, Moon RT, Perrimon N. Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways. Genes & Development. 12: 2610-22. PMID 9716412 DOI: 10.1101/Gad.12.16.2610  0.699
1998 Perrimon N. New advances in Drosophila provide opportunities to study gene functions. Proceedings of the National Academy of Sciences of the United States of America. 95: 9716-7. PMID 9707540 DOI: 10.1073/Pnas.95.17.9716  0.384
1998 Bellaiche Y, The I, Perrimon N. Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion. Nature. 394: 85-8. PMID 9665133 DOI: 10.1038/27932  0.634
1998 Perrimon N. Creating mosaics in Drosophila. The International Journal of Developmental Biology. 42: 243-7. PMID 9654004 DOI: 10.1387/Ijdb.9654004  0.354
1998 Duffy JB, Harrison DA, Perrimon N. Identifying loci required for follicular patterning using directed mosaics. Development (Cambridge, England). 125: 2263-71. PMID 9584125  0.584
1998 Mathey-Prevot B, Perrimon N. Mammalian and Drosophila blood: JAK of all trades? Cell. 92: 697-700. PMID 9529244 DOI: 10.1016/S0092-8674(00)81396-3  0.321
1998 Häcker U, Perrimon N. DRhoGEF2 encodes a member of the Dbl family of oncogenes and controls cell shape changes during gastrulation in Drosophila. Genes & Development. 12: 274-84. PMID 9436986 DOI: 10.1101/Gad.12.2.274  0.68
1997 Riesgo-Escovar JR, Hafen E, Hou XS, Goldstein ES, Perrimon N, Glise B, Noselli S, Kockel L, Zeitlinger J, Staszewski LM, Mlodzik M, Bohmann D. Connecting up the pathways in Drosophila development. Trends in Cell Biology. 7: 421-2. PMID 17708993 DOI: 10.1016/S0962-8924(97)88135-4  0.632
1997 Goode S, Perrimon N. Brainiac and fringe are similar pioneer proteins that impart specificity to notch signaling during Drosophila development. Cold Spring Harbor Symposia On Quantitative Biology. 62: 177-84. PMID 9598350 DOI: 10.1101/Sqb.1997.062.01.023  0.343
1997 Eberl DF, Duyk GM, Perrimon N. A genetic screen for mutations that disrupt an auditory response in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. 94: 14837-42. PMID 9405700 DOI: 10.1073/pnas.94.26.14837  0.645
1997 Häcker U, Lin X, Perrimon N. The Drosophila sugarless gene modulates Wingless signaling and encodes an enzyme involved in polysaccharide biosynthesis. Development (Cambridge, England). 124: 3565-73. PMID 9342049  0.651
1997 Goode S, Perrimon N. Inhibition of patterned cell shape change and cell invasion by Discs large during Drosophila oogenesis. Genes & Development. 11: 2532-44. PMID 9334318 DOI: 10.1101/Gad.11.19.2532  0.391
1997 Engstrom L, Noll E, Perrimon N. Paradigms to study signal transduction pathways in Drosophila. Current Topics in Developmental Biology. 35: 229-61. PMID 9292272 DOI: 10.1016/S0070-2153(08)60261-6  0.412
1997 Hou XS, Goldstein ES, Perrimon N. Drosophila Jun relays the Jun amino-terminal kinase signal transduction pathway to the Decapentaplegic signal transduction pathway in regulating epithelial cell sheet movement. Genes & Development. 11: 1728-37. PMID 9224721 DOI: 10.1101/Gad.11.13.1728  0.386
1997 Eberl DF, Lorenz LJ, Melnick MB, Sood V, Lasko P, Perrimon N. A new enhancer of position-effect variegation in Drosophila melanogaster encodes a putative RNA helicase that binds chromosomes and is regulated by the cell cycle. Genetics. 146: 951-63. PMID 9215899  0.662
1997 Li W, Perrimon N. Specificity of receptor tyrosine kinase signaling pathways: lessons from Drosophila. Genetic Engineering. 19: 167-82. PMID 9193108 DOI: 10.1007/978-1-4615-5925-2_9  0.696
1997 Perrimon N, Perkins LA. There must be 50 ways to rule the signal: the case of the Drosophila EGF receptor. Cell. 89: 13-6. PMID 9094709 DOI: 10.1016/S0092-8674(00)80177-4  0.345
1997 Yu Y, Li W, Su K, Yussa M, Han W, Perrimon N, Pick L. The nuclear hormone receptor Ftz-F1 is a cofactor for the Drosophila homeodomain protein Ftz. Nature. 385: 552-5. PMID 9020364 DOI: 10.1038/385552A0  0.67
1996 Kadowaki T, Wilder E, Klingensmith J, Zachary K, Perrimon N. The segment polarity gene porcupine encodes a putative multitransmembrane protein involved in Wingless processing. Genes & Development. 10: 3116-28. PMID 8985181 DOI: 10.1101/Gad.10.24.3116  0.701
1996 Perkins LA, Johnson MR, Melnick MB, Perrimon N. The nonreceptor protein tyrosine phosphatase corkscrew functions in multiple receptor tyrosine kinase pathways in Drosophila. Developmental Biology. 180: 63-81. PMID 8948575 DOI: 10.1006/Dbio.1996.0285  0.333
1996 Rulifson EJ, Micchelli CA, Axelrod JD, Perrimon N, Blair SS. wingless refines its own expression domain on the Drosophila wing margin. Nature. 384: 72-4. PMID 8900280 DOI: 10.1038/384072A0  0.767
1996 Klingensmith J, Yang Y, Axelrod JD, Beier DR, Perrimon N, Sussman DJ. Conservation of dishevelled structure and function between flies and mice: isolation and characterization of Dvl2. Mechanisms of Development. 58: 15-26. PMID 8887313 DOI: 10.1016/S0925-4773(96)00549-7  0.803
1996 Musacchio M, Perrimon N. The Drosophila kekkon genes: novel members of both the leucine-rich repeat and immunoglobulin superfamilies expressed in the CNS. Developmental Biology. 178: 63-76. PMID 8812109 DOI: 10.1006/dbio.1996.0198  0.397
1996 Duffy JB, Perrimon N. Recent advances in understanding signal transduction pathways in worms and flies. Current Opinion in Cell Biology. 8: 231-8. PMID 8791421 DOI: 10.1016/S0955-0674(96)80070-6  0.362
1996 Perrimon N. Serpentine proteins slither into the wingless and hedgehog fields. Cell. 86: 513-6. PMID 8752205 DOI: 10.1016/S0092-8674(00)80124-5  0.322
1996 Hou XS, Melnick MB, Perrimon N. Marelle acts downstream of the Drosophila HOP/JAK kinase and encodes a protein similar to the mammalian STATs. Cell. 84: 411-9. PMID 8608595 DOI: 10.1016/S0092-8674(00)81286-6  0.354
1996 Cleghon V, Gayko U, Copeland TD, Perkins LA, Perrimon N, Morrison DK. Drosophila terminal structure development is regulated by the compensatory activities of positive and negative phosphotyrosine signaling sites on the Torso RTK. Genes & Development. 10: 566-77. PMID 8598287 DOI: 10.1101/Gad.10.5.566  0.341
1996 Axelrod JD, Matsuno K, Artavanis-Tsakonas S, Perrimon N. Interaction between Wingless and Notch signaling pathways mediated by dishevelled. Science (New York, N.Y.). 271: 1826-32. PMID 8596950 DOI: 10.1126/Science.271.5257.1826  0.7
1996 Rulifson EJ, Micchelli CA, Axelrod JD, Perrimon N, Blair SS. Erratum: wingless refines its own expression domain on the Drosophila wing margin Nature. 384: 597-597. DOI: 10.1038/384597a0  0.63
1995 Perrimon N, Lu X, Hou XS, Hsu JC, Melnick MB, Chou TB, Perkins LA. Dissection of the Torso signal transduction pathway in Drosophila. Molecular Reproduction and Development. 42: 515-22. PMID 8607984 DOI: 10.1002/Mrd.1080420421  0.364
1995 Harrison DA, Binari R, Nahreini TS, Gilman M, Perrimon N. Activation of a Drosophila Janus kinase (JAK) causes hematopoietic neoplasia and developmental defects. The Embo Journal. 14: 2857-65. PMID 7796812 DOI: 10.1002/J.1460-2075.1995.Tb07285.X  0.565
1995 Yin JC, Wallach JS, Wilder EL, Klingensmith J, Dang D, Perrimon N, Zhou H, Tully T, Quinn WG. A Drosophila CREB/CREM homolog encodes multiple isoforms, including a cyclic AMP-dependent protein kinase-responsive transcriptional activator and antagonist. Molecular and Cellular Biology. 15: 5123-30. PMID 7651429 DOI: 10.1128/Mcb.15.9.5123  0.685
1995 Yoffe KB, Manoukian AS, Wilder EL, Brand AH, Perrimon N. Evidence for engrailed-independent wingless autoregulation in Drosophila. Developmental Biology. 170: 636-50. PMID 7649390 DOI: 10.1006/Dbio.1995.1243  0.601
1995 Rivera-Pomar R, Lu X, Perrimon N, Taubert H, Jäckle H. Activation of posterior gap gene expression in the Drosophila blastoderm. Nature. 376: 253-6. PMID 7617036 DOI: 10.1038/376253a0  0.326
1994 Binari R, Perrimon N. Stripe-specific regulation of pair-rule genes by hopscotch, a putative Jak family tyrosine kinase in Drosophila. Genes & Development. 8: 300-12. PMID 8314084 DOI: 10.1101/GAD.8.3.300  0.337
1994 Klingensmith J, Nusse R, Perrimon N. The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal Genes and Development. 8: 118-130. PMID 8288125 DOI: 10.1101/Gad.8.1.118  0.725
1994 Siegfried E, Wilder EL, Perrimon N. Components of wingless signalling in Drosophila. Nature. 367: 76-80. PMID 8107779 DOI: 10.1038/367076a0  0.421
1994 Siegfried E, Perrimon N. Drosophila wingless: a paradigm for the function and mechanism of Wnt signaling. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 16: 395-404. PMID 8080429 DOI: 10.1002/bies.950160607  0.423
1994 Perrimon N. Signalling pathways initiated by receptor protein tyrosine kinases in Drosophila. Current Opinion in Cell Biology. 6: 260-6. PMID 8024818 DOI: 10.1016/0955-0674(94)90145-7  0.338
1994 Sussman DJ, Klingensmith J, Salinas P, Adams PS, Nusse R, Perrimon N. Isolation and characterization of a mouse homolog of the Drosophila segment polarity gene dishevelled Developmental Biology. 166: 73-86. PMID 7958461 DOI: 10.1006/Dbio.1994.1297  0.704
1994 Brand AH, Perrimon N. Raf acts downstream of the EGF receptor to determine dorsoventral polarity during Drosophila oogenesis. Genes & Development. 8: 629-39. PMID 7926754 DOI: 10.1101/Gad.8.5.629  0.593
1994 Perrimon N. The genetic basis of patterned baldness in Drosophila. Cell. 76: 781-4. PMID 7907277 DOI: 10.1016/0092-8674(94)90351-4  0.41
1994 Perrimon N, Desplan C. Signal transduction in the early Drosophila embryo: when genetics meets biochemistry. Trends in Biochemical Sciences. 19: 509-13. PMID 7855897 DOI: 10.1016/0968-0004(94)90140-6  0.341
1994 Duffy JB, Perrimon N. The Torso pathway in Drosophila: Lessons on receptor tyrosine kinase signaling and pattern formation Developmental Biology. 166: 380-395. PMID 7813764 DOI: 10.1006/dbio.1994.1324  0.342
1994 Brand AH, Manoukian AS, Perrimon N. Ectopic expression in Drosophila. Methods in Cell Biology. 44: 635-54. PMID 7707973 DOI: 10.1016/S0091-679X(08)60936-X  0.572
1993 Harrison DA, Perrimon N. Simple and efficient generation of marked clones in Drosophila. Current Biology : Cb. 3: 424-33. PMID 15335709 DOI: 10.1016/0960-9822(93)90349-S  0.601
1993 Lu X, Chou TB, Williams NG, Roberts T, Perrimon N. Control of cell fate determination by p21ras/Ras1, an essential component of torso signaling in Drosophila. Genes & Development. 7: 621-32. PMID 8458578 DOI: 10.1101/Gad.7.4.621  0.38
1993 Perrimon N. The torso receptor protein-tyrosine kinase signaling pathway: an endless story. Cell. 74: 219-22. PMID 8343949 DOI: 10.1016/0092-8674(93)90412-J  0.355
1993 Noll E, Perkins LA, Mahowald AP, Perrimon N. Approaches to identify genes involved in Drosophila embryonic CNS development. Journal of Neurobiology. 24: 701-22. PMID 8331336 DOI: 10.1002/Neu.480240603  0.595
1993 Van Heuvel MD, Harryman-Samos C, Klingensmith J, Perrimon N, Nusse R. Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein Embo Journal. 12: 5293-5302. PMID 8262072 DOI: 10.1002/J.1460-2075.1993.Tb06225.X  0.692
1993 Brand AH, Perrimon N. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development (Cambridge, England). 118: 401-15. PMID 8223268  0.595
1993 Dang DT, Perrimon N. Use of a yeast site-specific recombinase to generate embryonic mosaics in Drosophila. Developmental Genetics. 13: 367-75. PMID 1292893 DOI: 10.1002/DVG.1020130507  0.324
1992 Rutledge BJ, Zhang K, Bier E, Jan YN, Perrimon N. The Drosophila spitz gene encodes a putative EGF-like growth factor involved in dorsal-ventral axis formation and neurogenesis. Genes & Development. 6: 1503-17. PMID 1644292 DOI: 10.1101/GAD.6.8.1503  0.375
1992 Perkins LA, Larsen I, Perrimon N. corkscrew encodes a putative protein tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso. Cell. 70: 225-36. PMID 1638629 DOI: 10.1016/0092-8674(92)90098-W  0.369
1992 Eberl DF, Perkins LA, Engelstein M, Hilliker AJ, Perrimon N. Genetic and developmental analysis of polytene section 17 of the X chromosome of Drosophila melanogaster. Genetics. 130: 569-83. PMID 1551578  0.643
1992 Siegfried E, Chou TB, Perrimon N. wingless signaling acts through zeste-white 3, the Drosophila homolog of glycogen synthase kinase-3, to regulate engrailed and establish cell fate. Cell. 71: 1167-79. PMID 1335365 DOI: 10.1016/S0092-8674(05)80065-0  0.411
1991 Zhang K, Smouse D, Perrimon N. The crooked neck gene of Drosophila contains a motif found in a family of yeast cell cycle genes. Genes & Development. 5: 1080-91. PMID 2044955 DOI: 10.1101/GAD.5.6.1080  0.371
1991 Perrimon N, Noll E, McCall K, Brand A. Generating lineage-specific markers to study Drosophila development Developmental Genetics. 12: 238-252. PMID 1651183 DOI: 10.1002/Dvg.1020120309  0.58
1990 Smouse D, Perrimon N. Genetic dissection of a complex neurological mutant, polyhomeotic, in Drosophila. Developmental Biology. 139: 169-85. PMID 2328834 DOI: 10.1016/0012-1606(90)90286-R  0.321
1990 Siegfried E, Ambrosio L, Perrimon N. Serine/threonine protein kinases in Drosophila. Trends in Genetics : Tig. 6: 357-62. PMID 2150900 DOI: 10.1016/0168-9525(90)90277-D  0.3
1990 Siegfried E, Perkins LA, Capaci TM, Perrimon N. Putative protein kinase product of the Drosophila segment-polarity gene zeste-white3. Nature. 345: 825-9. PMID 2113617 DOI: 10.1038/345825A0  0.348
1990 Perkins LA, Doctor JS, Zhang K, Stinson L, Perrimon N, Craig EA. Molecular and developmental characterization of the heat shock cognate 4 gene of Drosophila melanogaster. Molecular and Cellular Biology. 10: 3232-8. PMID 2111451 DOI: 10.1128/Mcb.10.6.3232  0.323
1990 Finkelstein R, Smouse D, Capaci TM, Spradling AC, Perrimon N. The orthodenticle gene encodes a novel homeo domain protein involved in the development of the Drosophila nervous system and ocellar visual structures. Genes & Development. 4: 1516-27. PMID 1979296 DOI: 10.1101/Gad.4.9.1516  0.592
1990 Finkelstein R, Perrimon N. The orthodenticle gene is regulated by bicoid and torso and specifies Drosophila head development. Nature. 346: 485-8. PMID 1974036 DOI: 10.1038/346485A0  0.345
1990 Zhang K, Chaillet JR, Perkins LA, Halazonetis TD, Perrimon N. Drosophila homolog of the mammalian jun oncogene is expressed during embryonic development and activates transcription in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 87: 6281-5. PMID 1696724 DOI: 10.1073/Pnas.87.16.6281  0.395
1989 Klingensmith J, Noll E, Perrimon N. The segment polarity phenotype of Drosophila involves differential tendencies toward transformation and cell death Developmental Biology. 134: 130-145. PMID 2731645 DOI: 10.1016/0012-1606(89)90084-5  0.689
1989 Perrimon N, Smouse D. Multiple functions of a Drosophila homeotic gene, zeste-white 3, during segmentation and neurogenesis. Developmental Biology. 135: 287-305. PMID 2570722 DOI: 10.1016/0012-1606(89)90180-2  0.378
1989 Ambrosio L, Mahowald AP, Perrimon N. Requirement of the Drosophila raf homologue for torso function. Nature. 342: 288-91. PMID 2554148 DOI: 10.1038/342288a0  0.609
1988 Oliver B, Perrimon N, Mahowald AP. Genetic evidence that the sans fille locus is involved in Drosophila sex determination Genetics. 120: 159-171. PMID 3220249  0.619
1988 Smouse D, Goodman C, Mahowald A, Perrimon N. polyhomeotic: a gene required for the embryonic development of axon pathways in the central nervous system of Drosophila. Genes & Development. 2: 830-42. PMID 2905316 DOI: 10.1101/Gad.2.7.830  0.599
1987 Perrimon N, Mahowald AP. Multiple functions of segment polarity genes in Drosophila. Developmental Biology. 119: 587-600. PMID 3803719 DOI: 10.1016/0012-1606(87)90061-3  0.568
1987 Oliver B, Perrimon N, Mahowald AP. The ovo locus is required for sex-specific germ line maintenance in Drosophila Genes & Development. 1: 913-923. PMID 3428601 DOI: 10.1101/Gad.1.9.913  0.671
1987 Petschek JP, Perrimon N, Mahowald AP. Region-specific defects in l(1)giant embryos of Drosophila melanogaster. Developmental Biology. 119: 175-89. PMID 3098602 DOI: 10.1016/0012-1606(87)90219-3  0.565
1986 Degelmann A, Hardy PA, Perrimon N, Mahowald AP. Developmental analysis of the torso-like phenotype in Drosophila produced by a maternal-effect locus. Developmental Biology. 115: 479-89. PMID 3709971 DOI: 10.1016/0012-1606(86)90268-X  0.621
1986 Perrimon N, Mahowald AP. l(1)hopscotch, A larval-pupal zygotic lethal with a specific maternal effect on segmentation in Drosophila. Developmental Biology. 118: 28-41. PMID 3095163 DOI: 10.1016/0012-1606(86)90070-9  0.565
1985 Mortin MA, Perrimon N, Bonner JJ. Clonal analysis of two mutations in the large subunit of RNA polymerase II of Drosophila. Molecular & General Genetics : Mgg. 199: 421-6. PMID 3929014 DOI: 10.1007/BF00330753  0.319
1985 Perrimon N, Engstrom L, Mahowald AP. A pupal lethal mutation with a paternally influenced maternal effect on embryonic development in Drosophila melanogaster. Developmental Biology. 110: 480-91. PMID 3926563 DOI: 10.1016/0012-1606(85)90105-8  0.603
1985 Konrad KD, Engstrom L, Perrimon N, Mahowald AP. Genetic analysis of oogenesis and the role of maternal gene expression in early development. Developmental Biology (New York, N.Y. : 1985). 1: 577-617. PMID 3917206  0.555
1984 Perrimon N, Engstrom L, Mahowald AP. The effects of zygotic lethal mutations on female germ-line functions in Drosophila. Developmental Biology. 105: 404-14. PMID 6479445 DOI: 10.1016/0012-1606(84)90297-5  0.595
1984 Perrimon N, Engstrom L, Mahowald AP. Developmental genetics of the 2E-F region of the Drosophila X chromosome: a region rich in "developmentally important" genes. Genetics. 108: 559-72. PMID 6437900  0.565
1983 Perrimon N, Gans M. Clonal analysis of the tissue specificity of recessive female-sterile mutations of Drosophila melanogaster using a dominant female-sterile mutation Fs(1)K1237. Developmental Biology. 100: 365-73. PMID 6418585 DOI: 10.1016/0012-1606(83)90231-2  0.593
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