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Scott A. Lujan, Ph.D. - Publications

Affiliations: 
2008 Biochemistry and Biophysics University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Structural Studies of Dynamic Cellular Processes
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38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Wu S, Longley MJ, Lujan SA, Kunkel TA, Copeland WC. Mitochondrial DNA Enrichment for Sensitive Next-Generation Sequencing. Methods in Molecular Biology (Clifton, N.J.). 2615: 427-441. PMID 36807807 DOI: 10.1007/978-1-0716-2922-2_28  0.392
2023 Zhou ZX, Follonier C, Lujan SA, Burkholder AB, Zakian VA, Kunkel TA. Pif1 family helicases promote mutation avoidance during DNA replication. Nucleic Acids Research. 50: 12844-12855. PMID 36533450 DOI: 10.1093/nar/gkac1127  0.462
2021 Zhou ZX, Lujan SA, Burkholder AB, St Charles J, Dahl J, Farrell CE, Williams JS, Kunkel TA. How asymmetric DNA replication achieves symmetrical fidelity. Nature Structural & Molecular Biology. 28: 1020-1028. PMID 34887558 DOI: 10.1038/s41594-021-00691-6  0.533
2021 Lujan SA, Kunkel TA. Stability across the Whole Nuclear Genome in the Presence and Absence of DNA Mismatch Repair. Cells. 10. PMID 34067668 DOI: 10.3390/cells10051224  0.337
2021 Kiktev DA, Dominska M, Zhang T, Dahl J, Stepchenkova EI, Mieczkowski P, Burgers PM, Lujan S, Burkholder A, Kunkel TA, Petes TD. The fidelity of DNA replication, particularly on GC-rich templates, is reduced by defects of the Fe-S cluster in DNA polymerase δ. Nucleic Acids Research. PMID 34019669 DOI: 10.1093/nar/gkab371  0.38
2021 Zhou ZX, Williams JS, Lujan SA, Kunkel TA. Ribonucleotide incorporation into DNA during DNA replication and its consequences. Critical Reviews in Biochemistry and Molecular Biology. 1-31. PMID 33461360 DOI: 10.1080/10409238.2020.1869175  0.44
2019 Donnianni RA, Zhou ZX, Lujan SA, Al-Zain A, Garcia V, Glancy E, Burkholder AB, Kunkel TA, Symington LS. DNA Polymerase Delta Synthesizes Both Strands during Break-Induced Replication. Molecular Cell. PMID 31495565 DOI: 10.1016/J.Molcel.2019.07.033  0.588
2019 Garbacz MA, Lujan SA, Kunkel TA. Opportunities for new studies of nuclear DNA replication enzymology in budding yeast. Current Genetics. PMID 31493018 DOI: 10.1007/S00294-019-01023-4  0.55
2019 Zhou ZX, Lujan SA, Burkholder AB, Garbacz MA, Kunkel TA. Roles for DNA polymerase δ in initiating and terminating leading strand DNA replication. Nature Communications. 10: 3992. PMID 31488849 DOI: 10.1038/S41467-019-11995-Z  0.571
2019 Williams JS, Lujan SA, Zhou ZX, Burkholder AB, Clark AB, Fargo DC, Kunkel TA. Genome-wide mutagenesis resulting from topoisomerase 1-processing of unrepaired ribonucleotides in DNA. Dna Repair. 102641. PMID 31311768 DOI: 10.1016/J.Dnarep.2019.102641  0.513
2019 Garbacz MA, Cox PB, Sharma S, Lujan SA, Chabes A, Kunkel TA. The absence of the catalytic domains of Saccharomyces cerevisiae DNA polymerase ϵ strongly reduces DNA replication fidelity. Nucleic Acids Research. PMID 30698744 DOI: 10.1093/Nar/Gkz048  0.554
2018 Burkholder AB, Lujan SA, Lavender CA, Grimm SA, Kunkel TA, Fargo DC. Muver, a computational framework for accurately calling accumulated mutations. Bmc Genomics. 19: 345. PMID 29743009 DOI: 10.1186/S12864-018-4753-3  0.362
2018 Garbacz MA, Lujan SA, Burkholder AB, Cox PB, Wu Q, Zhou ZX, Haber JE, Kunkel TA. Evidence that DNA polymerase δ contributes to initiating leading strand DNA replication in Saccharomyces cerevisiae. Nature Communications. 9: 858. PMID 29487291 DOI: 10.1038/S41467-018-03270-4  0.595
2018 Orebaugh CD, Lujan SA, Burkholder AB, Clausen AR, Kunkel TA. Mapping Ribonucleotides Incorporated into DNA by Hydrolytic End-Sequencing. Methods in Molecular Biology (Clifton, N.J.). 1672: 329-345. PMID 29043634 DOI: 10.1007/978-1-4939-7306-4_23  0.522
2017 Segovia R, Shen Y, Lujan SA, Jones SJ, Stirling PC. Hypermutation signature reveals a slippage and realignment model of translesion synthesis by Rev3 polymerase in cisplatin-treated yeast. Proceedings of the National Academy of Sciences of the United States of America. PMID 28223526 DOI: 10.1073/Pnas.1618555114  0.473
2016 Lujan SA, Williams JS, Kunkel TA. DNA Polymerases Divide the Labor of Genome Replication. Trends in Cell Biology. PMID 27262731 DOI: 10.1016/J.Tcb.2016.04.012  0.578
2016 Williams JS, Lujan SA, Kunkel TA. Processing ribonucleotides incorporated during eukaryotic DNA replication. Nature Reviews. Molecular Cell Biology. PMID 27093943 DOI: 10.1038/Nrm.2016.37  0.596
2016 Lujan SA, Williams JS, Kunkel TA. Eukaryotic genome instability in light of asymmetric DNA replication. Critical Reviews in Biochemistry and Molecular Biology. 51: 43-52. PMID 26822554 DOI: 10.3109/10409238.2015.1117055  0.577
2015 Watt DL, Buckland RJ, Lujan SA, Kunkel TA, Chabes A. Genome-wide analysis of the specificity and mechanisms of replication infidelity driven by imbalanced dNTP pools. Nucleic Acids Research. PMID 26609135 DOI: 10.1093/Nar/Gkv1298  0.536
2015 Conover HN, Lujan SA, Chapman MJ, Cornelio DA, Sharif R, Williams JS, Clark AB, Camilo F, Kunkel TA, Argueso JL. Stimulation of Chromosomal Rearrangements by Ribonucleotides. Genetics. PMID 26400612 DOI: 10.1534/Genetics.115.181149  0.525
2015 St Charles JA, Liberti SE, Williams JS, Lujan SA, Kunkel TA. Quantifying the contributions of base selectivity, proofreading and mismatch repair to nuclear DNA replication in Saccharomyces cerevisiae. Dna Repair. 31: 41-51. PMID 25996407 DOI: 10.1016/J.Dnarep.2015.04.006  0.557
2015 Lujan SA, Clark AB, Kunkel TA. Differences in genome-wide repeat sequence instability conferred by proofreading and mismatch repair defects. Nucleic Acids Research. 43: 4067-74. PMID 25824945 DOI: 10.1093/Nar/Gkv271  0.482
2015 Williams JS, Clausen AR, Lujan SA, Marjavaara L, Clark AB, Burgers PM, Chabes A, Kunkel TA. Evidence that processing of ribonucleotides in DNA by topoisomerase 1 is leading-strand specific. Nature Structural & Molecular Biology. 22: 291-7. PMID 25751426 DOI: 10.1038/Nsmb.2989  0.557
2015 Clausen AR, Lujan SA, Burkholder AB, Orebaugh CD, Williams JS, Clausen MF, Malc EP, Mieczkowski PA, Fargo DC, Smith DJ, Kunkel TA. Tracking replication enzymology in vivo by genome-wide mapping of ribonucleotide incorporation. Nature Structural & Molecular Biology. 22: 185-91. PMID 25622295 DOI: 10.1038/Nsmb.2957  0.573
2015 Lujan SA, Williams JS, Kunkel TA. Eukaryotic genome instability in light of asymmetric DNA replication Critical Reviews in Biochemistry and Molecular Biology. 1-10. DOI: 10.3109/10409238.2015.1117055  0.422
2015 St Charles JA, Liberti SE, Williams JS, Lujan SA, Kunkel TA. Quantifying the contributions of base selectivity, proofreading and mismatch repair to nuclear DNA replication in Saccharomyces cerevisiae Dna Repair. 31: 41-51. DOI: 10.1016/j.dnarep.2015.04.006  0.462
2014 Lujan SA, Clausen AR, Clark AB, MacAlpine HK, MacAlpine DM, Malc EP, Mieczkowski PA, Burkholder AB, Fargo DC, Gordenin DA, Kunkel TA. Heterogeneous polymerase fidelity and mismatch repair bias genome variation and composition. Genome Research. 24: 1751-64. PMID 25217194 DOI: 10.1101/Gr.178335.114  0.493
2013 Lujan SA, Williams JS, Clausen AR, Clark AB, Kunkel TA. Ribonucleotides are signals for mismatch repair of leading-strand replication errors. Molecular Cell. 50: 437-43. PMID 23603118 DOI: 10.1016/J.Molcel.2013.03.017  0.594
2013 Williams JS, Smith DJ, Marjavaara L, Lujan SA, Chabes A, Kunkel TA. Topoisomerase 1-mediated removal of ribonucleotides from nascent leading-strand DNA. Molecular Cell. 49: 1010-5. PMID 23375499 DOI: 10.1016/J.Molcel.2012.12.021  0.569
2012 Lujan SA, Williams JS, Pursell ZF, Abdulovic-Cui AA, Clark AB, Nick McElhinny SA, Kunkel TA. Mismatch repair balances leading and lagging strand DNA replication fidelity. Plos Genetics. 8: e1003016. PMID 23071460 DOI: 10.1371/Journal.Pgen.1003016  0.58
2012 Stone JE, Lujan SA, Kunkel TA, Kunkel TA. DNA polymerase zeta generates clustered mutations during bypass of endogenous DNA lesions in Saccharomyces cerevisiae. Environmental and Molecular Mutagenesis. 53: 777-86. PMID 22965922 DOI: 10.1002/Em.21728  0.515
2011 Clark AB, Lujan SA, Kissling GE, Kunkel TA. Mismatch repair-independent tandem repeat sequence instability resulting from ribonucleotide incorporation by DNA polymerase ε. Dna Repair. 10: 476-82. PMID 21414850 DOI: 10.1016/J.Dnarep.2011.02.001  0.597
2010 Larrea AA, Lujan SA, Nick McElhinny SA, Mieczkowski PA, Resnick MA, Gordenin DA, Kunkel TA. Genome-wide model for the normal eukaryotic DNA replication fork. Proceedings of the National Academy of Sciences of the United States of America. 107: 17674-9. PMID 20876092 DOI: 10.1073/Pnas.1010178107  0.566
2010 Larrea AA, Lujan SA, Kunkel TA. SnapShot: DNA mismatch repair. Cell. 141: 730.e1. PMID 20478261 DOI: 10.1016/J.Cell.2010.05.002  0.541
2010 Nash RP, Habibi S, Cheng Y, Lujan SA, Redinbo MR. The mechanism and control of DNA transfer by the conjugative relaxase of resistance plasmid pCU1. Nucleic Acids Research. 38: 5929-43. PMID 20448025 DOI: 10.1093/Nar/Gkq303  0.593
2009 Stone JE, Kissling GE, Lujan SA, Rogozin IB, Stith CM, Burgers PM, Kunkel TA. Low-fidelity DNA synthesis by the L979F mutator derivative of Saccharomyces cerevisiae DNA polymerase zeta. Nucleic Acids Research. 37: 3774-87. PMID 19380376 DOI: 10.1093/Nar/Gkp238  0.493
2008 Potts RG, Lujan SA, Redinbo MR. Winning the asymmetric war: new strategies for combating antibacterial resistance. Future Microbiology. 3: 119-23. PMID 18366330 DOI: 10.2217/17460913.3.2.119  0.523
2007 Lujan SA, Guogas LM, Ragonese H, Matson SW, Redinbo MR. Disrupting antibiotic resistance propagation by inhibiting the conjugative DNA relaxase. Proceedings of the National Academy of Sciences of the United States of America. 104: 12282-7. PMID 17630285 DOI: 10.1073/Pnas.0702760104  0.674
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