Kevin R. Thornton - Publications

Affiliations: 
University of California, Irvine, Irvine, CA 
Area:
population genetics
Website:
http://www.faculty.uci.edu/profile.cfm?faculty_id=5379

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Ralph P, Thornton K, Kelleher J. Efficiently Summarizing Relationships in Large Samples: A General Duality Between Statistics of Genealogies and Genomes. Genetics. PMID 32357960 DOI: 10.1534/Genetics.120.303253  0.45
2019 Thornton KR. Polygenic Adaptation to an Environmental Shift: Temporal Dynamics of Variation Under Gaussian Stabilizing Selection and Additive Effects on a Single Trait. Genetics. PMID 31653678 DOI: 10.1534/genetics.119.302662  0.349
2018 Stetter MG, Thornton K, Ross-Ibarra J. Genetic architecture and selective sweeps after polygenic adaptation to distant trait optima. Plos Genetics. 14: e1007794. PMID 30452452 DOI: 10.1371/Journal.Pgen.1007794  0.438
2018 Kelleher J, Thornton KR, Ashander J, Ralph PL. Efficient pedigree recording for fast population genetics simulation. Plos Computational Biology. 14: e1006581. PMID 30383757 DOI: 10.1371/journal.pcbi.1006581  0.37
2017 Sanjak JS, Sidorenko J, Robinson MR, Thornton KR, Visscher PM. Evidence of directional and stabilizing selection in contemporary humans. Proceedings of the National Academy of Sciences of the United States of America. PMID 29255044 DOI: 10.1073/pnas.1707227114  0.378
2017 Rogers RL, Shao L, Thornton KR. Tandem duplications lead to novel expression patterns through exon shuffling in Drosophila yakuba. Plos Genetics. 13: e1006795. PMID 28531189 DOI: 10.1371/Journal.Pgen.1006795  0.513
2017 Sanjak JS, Long AD, Thornton KR. A Model of Compound Heterozygous, Loss-of-Function Alleles Is Broadly Consistent with Observations from Complex-Disease GWAS Datasets. Plos Genetics. 13: e1006573. PMID 28103232 DOI: 10.1371/journal.pgen.1006573  0.453
2016 Sanjak JS, Long AD, Thornton KR. Efficient Software for Multi-marker, Region-Based Analysis of GWAS Data. G3 (Bethesda, Md.). PMID 26865700 DOI: 10.1534/g3.115.026013  0.414
2015 Rogers RL, Cridland JM, Shao L, Hu TT, Andolfatto P, Thornton KR. Tandem Duplications and the Limits of Natural Selection in Drosophila yakuba and Drosophila simulans. Plos One. 10: e0132184. PMID 26176952 DOI: 10.1371/Journal.Pone.0132184  0.793
2015 Cridland JM, Thornton KR, Long AD. Gene expression variation in Drosophila melanogaster due to rare transposable element insertion alleles of large effect. Genetics. 199: 85-93. PMID 25335504 DOI: 10.1534/Genetics.114.170837  0.744
2014 Rogers RL, Shao L, Sanjak JS, Andolfatto P, Thornton KR. Revised annotations, sex-biased expression, and lineage-specific genes in the Drosophila melanogaster group. G3 (Bethesda, Md.). 4: 2345-51. PMID 25273863 DOI: 10.1534/G3.114.013532  0.489
2014 Rogers RL, Cridland JM, Shao L, Hu TT, Andolfatto P, Thornton KR. Landscape of standing variation for tandem duplications in Drosophila yakuba and Drosophila simulans. Molecular Biology and Evolution. 31: 1750-66. PMID 24710518 DOI: 10.1093/Molbev/Msu124  0.779
2014 Baldwin-Brown JG, Long AD, Thornton KR. The power to detect quantitative trait loci using resequenced, experimentally evolved populations of diploid, sexual organisms. Molecular Biology and Evolution. 31: 1040-55. PMID 24441104 DOI: 10.1093/molbev/msu048  0.403
2013 Cridland JM, Macdonald SJ, Long AD, Thornton KR. Abundance and distribution of transposable elements in two Drosophila QTL mapping resources. Molecular Biology and Evolution. 30: 2311-27. PMID 23883524 DOI: 10.1093/Molbev/Mst129  0.781
2013 Thornton KR, Foran AJ, Long AD. Properties and modeling of GWAS when complex disease risk is due to non-complementing, deleterious mutations in genes of large effect. Plos Genetics. 9: e1003258. PMID 23437004 DOI: 10.1371/journal.pgen.1003258  0.451
2013 Hu TT, Eisen MB, Thornton KR, Andolfatto P. A second-generation assembly of the Drosophila simulans genome provides new insights into patterns of lineage-specific divergence. Genome Research. 23: 89-98. PMID 22936249 DOI: 10.1101/Gr.141689.112  0.535
2012 Ramos E, Levinson BT, Chasnoff S, Hughes A, Young AL, Thornton K, Li A, Vallania FL, Province M, Druley TE. Population-based rare variant detection via pooled exome or custom hybridization capture with or without individual indexing. Bmc Genomics. 13: 683. PMID 23216810 DOI: 10.1186/1471-2164-13-683  0.325
2012 Garrigan D, Kingan SB, Geneva AJ, Andolfatto P, Clark AG, Thornton KR, Presgraves DC. Genome sequencing reveals complex speciation in the Drosophila simulans clade. Genome Research. 22: 1499-511. PMID 22534282 DOI: 10.1101/Gr.130922.111  0.587
2012 Mackay TF, Richards S, Stone EA, Barbadilla A, Ayroles JF, Zhu D, Casillas S, Han Y, Magwire MM, Cridland JM, Richardson MF, Anholt RR, Barrón M, Bess C, Blankenburg KP, ... ... Thornton KR, et al. The Drosophila melanogaster Genetic Reference Panel. Nature. 482: 173-8. PMID 22318601 DOI: 10.1038/Nature10811  0.77
2011 Sainudiin R, Thornton K, Harlow J, Booth J, Stillman M, Yoshida R, Griffiths R, McVean G, Donnelly P. Experiments with the site frequency spectrum. Bulletin of Mathematical Biology. 73: 829-72. PMID 21181503 DOI: 10.1007/S11538-010-9605-5  0.316
2010 Burke MK, Dunham JP, Shahrestani P, Thornton KR, Rose MR, Long AD. Genome-wide analysis of a long-term evolution experiment with Drosophila. Nature. 467: 587-90. PMID 20844486 DOI: 10.1038/Nature09352  0.476
2010 Cridland JM, Thornton KR. Validation of rearrangement break points identified by paired-end sequencing in natural populations of Drosophila melanogaster. Genome Biology and Evolution. 2: 83-101. PMID 20333226 DOI: 10.1093/Gbe/Evq001  0.779
2009 Gilad Y, Pritchard JK, Thornton K. Characterizing natural variation using next-generation sequencing technologies. Trends in Genetics : Tig. 25: 463-71. PMID 19801172 DOI: 10.1016/j.tig.2009.09.003  0.47
2008 Jensen JD, Thornton KR, Andolfatto P. An approximate bayesian estimator suggests strong, recurrent selective sweeps in Drosophila. Plos Genetics. 4: e1000198. PMID 18802463 DOI: 10.1371/Journal.Pgen.1000198  0.419
2008 Jensen JD, Thornton KR, Aquadro CF. Inferring selection in partially sequenced regions. Molecular Biology and Evolution. 25: 438-46. PMID 18165259 DOI: 10.1093/Molbev/Msm273  0.41
2007 Thornton KR. The neutral coalescent process for recent gene duplications and copy-number variants. Genetics. 177: 987-1000. PMID 17720930 DOI: 10.1534/genetics.107.074948  0.526
2007 Tang K, Thornton KR, Stoneking M. A new approach for using genome scans to detect recent positive selection in the human genome. Plos Biology. 5: e171. PMID 17579516 DOI: 10.1371/Journal.Pbio.0050171  0.474
2007 Jensen JD, Thornton KR, Bustamante CD, Aquadro CF. On the utility of linkage disequilibrium as a statistic for identifying targets of positive selection in nonequilibrium populations. Genetics. 176: 2371-9. PMID 17565955 DOI: 10.1534/Genetics.106.069450  0.407
2007 Thornton KR, Jensen JD, Becquet C, Andolfatto P. Progress and prospects in mapping recent selection in the genome. Heredity. 98: 340-8. PMID 17473869 DOI: 10.1038/Sj.Hdy.6800967  0.489
2007 Thornton KR, Jensen JD. Controlling the false-positive rate in multilocus genome scans for selection. Genetics. 175: 737-50. PMID 17110489 DOI: 10.1534/Genetics.106.064642  0.489
2006 Bachtrog D, Thornton K, Clark A, Andolfatto P. Extensive introgression of mitochondrial DNA relative to nuclear genes in the Drosophila yakuba species group. Evolution; International Journal of Organic Evolution. 60: 292-302. PMID 16610321 DOI: 10.1111/J.0014-3820.2006.Tb01107.X  0.721
2006 Thornton K, Bachtrog D, Andolfatto P. X chromosomes and autosomes evolve at similar rates in Drosophila: no evidence for faster-X protein evolution. Genome Research. 16: 498-504. PMID 16520459 DOI: 10.1101/Gr.4447906  0.713
2006 Wilson GM, Flibotte S, Missirlis PI, Marra MA, Jones S, Thornton K, Clark AG, Holt RA. Identification by full-coverage array CGH of human DNA copy number increases relative to chimpanzee and gorilla. Genome Research. 16: 173-81. PMID 16365383 DOI: 10.1101/Gr.4456006  0.62
2006 Thornton K, Andolfatto P. Approximate Bayesian inference reveals evidence for a recent, severe bottleneck in a Netherlands population of Drosophila melanogaster. Genetics. 172: 1607-19. PMID 16299396 DOI: 10.1534/Genetics.105.048223  0.458
2005 Thornton K. Recombination and the properties of Tajima's D in the context of approximate-likelihood calculation Genetics. 171: 2143-2148. PMID 15998723 DOI: 10.1534/genetics.105.043786  0.347
2005 Haddrill PR, Thornton KR, Charlesworth B, Andolfatto P. Multilocus patterns of nucleotide variability and the demographic and selection history of Drosophila melanogaster populations. Genome Research. 15: 790-9. PMID 15930491 DOI: 10.1101/Gr.3541005  0.437
2005 Richards S, Liu Y, Bettencourt BR, Hradecky P, Letovsky S, Nielsen R, Thornton K, Hubisz MJ, Chen R, Meisel RP, Couronne O, Hua S, Smith MA, Zhang P, Liu J, et al. Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution. Genome Research. 15: 1-18. PMID 15632085 DOI: 10.1101/Gr.3059305  0.764
2005 Thornton K, Long M. Excess of amino acid substitutions relative to polymorphism between X-linked duplications in Drosophila melanogaster. Molecular Biology and Evolution. 22: 273-84. PMID 15483321 DOI: 10.1093/molbev/msi015  0.625
2004 Wang W, Thornton K, Emerson JJ, Long M. Nucleotide variation and recombination along the fourth chromosome in Drosophila simulans. Genetics. 166: 1783-94. PMID 15126398 DOI: 10.1534/Genetics.166.4.1783  0.763
2003 Long M, Betrán E, Thornton K, Wang W. The origin of new genes: glimpses from the young and old. Nature Reviews. Genetics. 4: 865-75. PMID 14634634 DOI: 10.1038/Nrg1204  0.772
2003 Thornton K. libsequence: A C++ class library for evolutionary genetic analysis Bioinformatics. 19: 2325-2327. PMID 14630667 DOI: 10.1093/bioinformatics/btg316  0.339
2002 Betrán E, Thornton K, Long M. Retroposed new genes out of the X in Drosophila. Genome Research. 12: 1854-9. PMID 12466289 DOI: 10.1101/gr.6049  0.78
2002 Thornton K, Long M. Rapid divergence of gene duplicates on the Drosophila melanogaster X chromosome. Molecular Biology and Evolution. 19: 918-25. PMID 12032248 DOI: 10.1093/Oxfordjournals.Molbev.A004149  0.642
2002 Wang W, Thornton K, Berry A, Long M. Nucleotide variation along the Drosophila melanogaster fourth chromosome. Science (New York, N.Y.). 295: 134-7. PMID 11778050 DOI: 10.1126/Science.1064521  0.644
2001 Long M, Thornton K. Gene duplication and evolution. Science (New York, N.Y.). 293: 1551. PMID 11533445 DOI: 10.1126/science.293.5535.1551a  0.675
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