Markus Affolter - Publications

Affiliations: 
Biozentrum, University of Basel, Basel, Basel-Stadt, Switzerland 

155 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Born G, Bieli D, Metzler M, Gohl DM, Affolter M, Müller M. No apparent role for the Wari insulator in transcriptional regulation of the endogenous gene of . Micropublication Biology. 2023. PMID 37090157 DOI: 10.17912/micropub.biology.000702  0.517
2022 Lepeta K, Roubinet C, Bauer M, Vigano MA, Aguilar G, Kanca O, Ochoa-Espinosa A, Bieli D, Cabernard C, Caussinus E, Affolter M. Engineered kinases as a tool for phosphorylation of selected targets in vivo. The Journal of Cell Biology. 221. PMID 36102907 DOI: 10.1083/jcb.202106179  0.741
2020 Galeone A, Adams JM, Matsuda S, Presa MF, Pandey A, Han SY, Tachida Y, Hirayama H, Vaccari T, Suzuki T, Lutz CM, Affolter M, Zuberi A, Jafar-Nejad H. Regulation of BMP4/Dpp retrotranslocation and signaling by deglycosylation. Elife. 9. PMID 32720893 DOI: 10.7554/Elife.55596  0.342
2019 Aguilar G, Matsuda S, Vigano MA, Affolter M. Using Nanobodies to Study Protein Function in Developing Organisms. Antibodies (Basel, Switzerland). 8. PMID 31544822 DOI: 10.3390/antib8010016  0.329
2019 Aguilar G, Vigano MA, Affolter M, Matsuda S. Reflections on the use of protein binders to study protein function in developmental biology. Wiley Interdisciplinary Reviews. Developmental Biology. e356. PMID 31265212 DOI: 10.1002/wdev.356  0.348
2019 Affolter M. Drosophila research: From the genome to the proteome Comptes Rendus Biologies. 342: 248-249. DOI: 10.1016/j.crvi.2019.09.003  0.379
2018 Postika N, Metzler M, Affolter M, Müller M, Schedl P, Georgiev P, Kyrchanova O. Boundaries mediate long-distance interactions between enhancers and promoters in the Drosophila Bithorax complex. Plos Genetics. 14: e1007702. PMID 30540750 DOI: 10.1371/Journal.Pgen.1007702  0.664
2018 Hübner K, Cabochette P, Diéguez-Hurtado R, Wiesner C, Wakayama Y, Grassme KS, Hubert M, Guenther S, Belting HG, Affolter M, Adams RH, Vanhollebeke B, Herzog W. Wnt/β-catenin signaling regulates VE-cadherin-mediated anastomosis of brain capillaries by counteracting S1pr1 signaling. Nature Communications. 9: 4860. PMID 30451830 DOI: 10.1038/s41467-018-07302-x  0.319
2018 Angulo-Urarte A, Casado P, Castillo SD, Kobialka P, Kotini MP, Figueiredo AM, Castel P, Rajeeve V, Milà-Guasch M, Millan J, Wiesner C, Serra H, Muixi L, Casanovas O, Viñals F, ... Affolter M, et al. Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility. Nature Communications. 9: 4826. PMID 30446640 DOI: 10.1038/s41467-018-07172-3  0.373
2018 Kotini MP, Mäe MA, Belting HG, Betsholtz C, Affolter M. Sprouting and anastomosis in the Drosophila trachea and the vertebrate vasculature: Similarities and differences in cell behaviour. Vascular Pharmacology. PMID 30423447 DOI: 10.1016/j.vph.2018.11.002  0.364
2018 Vigano MA, Bieli D, Schaefer JV, Jakob RP, Matsuda S, Maier T, Plückthun A, Affolter M. DARPins recognizing mTFP1 as novel reagents for and protein manipulations. Biology Open. PMID 30237292 DOI: 10.1242/Bio.036749  0.36
2018 Paatero I, Sauteur L, Lee M, Lagendijk AK, Heutschi D, Wiesner C, Guzmán C, Bieli D, Hogan BM, Affolter M, Belting HG. Junction-based lamellipodia drive endothelial cell rearrangements in vivo via a VE-cadherin-F-actin based oscillatory cell-cell interaction. Nature Communications. 9: 3545. PMID 30171187 DOI: 10.1038/s41467-018-05851-9  0.342
2018 Harmansa S, Affolter M. Protein binders and their applications in developmental biology. Development (Cambridge, England). 145. PMID 29374062 DOI: 10.1242/dev.148874  0.337
2017 Roubinet C, Tsankova A, Pham TT, Monnard A, Caussinus E, Affolter M, Cabernard C. Spatio-temporally separated cortical flows and spindle geometry establish physical asymmetry in fly neural stem cells. Nature Communications. 8: 1383. PMID 29123099 DOI: 10.1038/S41467-017-01391-W  0.714
2017 Lagendijk AK, Gomez GA, Baek S, Hesselson D, Hughes WE, Paterson S, Conway DE, Belting HG, Affolter M, Smith KA, Schwartz MA, Yap AS, Hogan BM. Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish. Nature Communications. 8: 1402. PMID 29123087 DOI: 10.1038/S41467-017-01325-6  0.353
2017 Ochoa-Espinosa A, Harmansa S, Caussinus E, Affolter M. Myosin II is not required for Drosophila tracheal branch elongation and cell intercalation. Development (Cambridge, England). 144: 2961-2968. PMID 28811312 DOI: 10.1242/Jcs.209569  0.788
2017 Matsuda S, Affolter M. Dpp from the anterior stripe of cells is crucial for the growth of the Drosophila wing disc. Elife. 6. PMID 28675373 DOI: 10.7554/eLife.22319  0.315
2017 Harmansa S, Alborelli I, Bieli D, Caussinus E, Affolter M. A nanobody-based toolset to investigate the role of protein localization and dispersal in Drosophila. Elife. 6. PMID 28395731 DOI: 10.7554/eLife.22549  0.363
2017 Nakajima H, Yamamoto K, Agarwala S, Terai K, Fukui H, Fukuhara S, Ando K, Miyazaki T, Yokota Y, Schmelzer E, Belting HG, Affolter M, Lecaudey V, Mochizuki N. Flow-Dependent Endothelial YAP Regulation Contributes to Vessel Maintenance. Developmental Cell. 40: 523-536.e6. PMID 28350986 DOI: 10.1016/j.devcel.2017.02.019  0.326
2017 Sauteur L, Affolter M, Belting HG. Distinct and redundant functions of Esam and VE-cadherin during vascular morphogenesis. Development (Cambridge, England). PMID 28264837 DOI: 10.1242/dev.140038  0.372
2017 Matsuda S, Affolter M. Author response: Dpp from the anterior stripe of cells is crucial for the growth of the Drosophila wing disc Elife. DOI: 10.7554/Elife.22319.013  0.317
2016 Caussinus E, Affolter M. deGradFP: A System to Knockdown GFP-Tagged Proteins. Methods in Molecular Biology (Clifton, N.J.). 1478: 177-187. PMID 27730581 DOI: 10.1007/978-1-4939-6371-3_9  0.354
2016 Betz C, Lenard A, Belting HG, Affolter M. Cell behaviors and dynamics during angiogenesis. Development (Cambridge, England). 143: 2249-60. PMID 27381223 DOI: 10.1242/dev.135616  0.31
2016 Aydogan V, Belting HG, Affolter M. Mapping the molecular steps of secretory-lysosome-driven tracheal tube fusion. Nature Cell Biology. 18: 720-2. PMID 27350443 DOI: 10.1038/ncb3383  0.32
2016 Affolter M. Seeing is Believing, or How GFP Changed My Approach to Science. Current Topics in Developmental Biology. 116: 1-16. PMID 26970610 DOI: 10.1016/bs.ctdb.2015.12.001  0.34
2016 Bieli D, Alborelli I, Harmansa S, Matsuda S, Caussinus E, Affolter M. Development and Application of Functionalized Protein Binders in Multicellular Organisms International Review of Cell and Molecular Biology. 325: 181-213. DOI: 10.1016/bs.ircmb.2016.02.006  0.36
2015 Matsuda S, Harmansa S, Affolter M. BMP morphogen gradients in flies. Cytokine & Growth Factor Reviews. PMID 26684043 DOI: 10.1016/j.cytogfr.2015.11.003  0.343
2015 Ittig SJ, Schmutz C, Kasper CA, Amstutz M, Schmidt A, Sauteur L, Vigano MA, Low SH, Affolter M, Cornelis GR, Nigg EA, Arrieumerlou C. A bacterial type III secretion-based protein delivery tool for broad applications in cell biology. The Journal of Cell Biology. 211: 913-31. PMID 26598622 DOI: 10.1083/Jcb.201502074  0.342
2015 Harmansa S, Hamaratoglu F, Affolter M, Caussinus E. Dpp spreading is required for medial but not for lateral wing disc growth. Nature. PMID 26550827 DOI: 10.1038/Nature15712  0.761
2015 Bieli D, Kanca O, Requena D, Hamaratoglu F, Gohl D, Schedl P, Affolter M, Slattery M, Müller M, Estella C. Establishment of a Developmental Compartment Requires Interactions between Three Synergistic Cis-regulatory Modules. Plos Genetics. 11: e1005376. PMID 26468882 DOI: 10.1371/Journal.Pgen.1005376  0.788
2015 Bürglin TR, Affolter M. Homeodomain proteins: an update. Chromosoma. PMID 26464018 DOI: 10.1007/s00412-015-0543-8  0.371
2015 Aydogan V, Lenard A, Denes AS, Sauteur L, Belting HG, Affolter M. Endothelial cell division in angiogenic sprouts of differing cellular architecture. Biology Open. 4: 1259-69. PMID 26369932 DOI: 10.1242/bio.012740  0.377
2015 Denes AS, Kanca O, Affolter M. A cellular process that includes asymmetric cytokinesis remodels the dorsal tracheal branches in Drosophila larvae. Development (Cambridge, England). 142: 1794-805. PMID 25968315 DOI: 10.1242/Dev.118372  0.732
2015 Lenard A, Daetwyler S, Betz C, Ellertsdottir E, Belting HG, Huisken J, Affolter M. Endothelial cell self-fusion during vascular pruning. Plos Biology. 13: e1002126. PMID 25884426 DOI: 10.1371/journal.pbio.1002126  0.361
2015 Bieli D, Kanca O, Gohl D, Denes A, Schedl P, Affolter M, Müller M. The Drosophila melanogaster Mutants apblot and apXasta Affect an Essential apterous Wing Enhancer. G3 (Bethesda, Md.). 5: 1129-43. PMID 25840432 DOI: 10.1534/G3.115.017707  0.789
2015 Phng LK, Gebala V, Bentley K, Philippides A, Wacker A, Mathivet T, Sauteur L, Stanchi F, Belting HG, Affolter M, Gerhardt H. Formin-mediated actin polymerization at endothelial junctions is required for vessel lumen formation and stabilization. Developmental Cell. 32: 123-32. PMID 25584798 DOI: 10.1016/J.Devcel.2014.11.017  0.309
2014 Brauchle M, Hansen S, Caussinus E, Lenard A, Ochoa-Espinosa A, Scholz O, Sprecher SG, Plückthun A, Affolter M. Protein interference applications in cellular and developmental biology using DARPins that recognize GFP and mCherry. Biology Open. 3: 1252-61. PMID 25416061 DOI: 10.1242/Bio.201410041  0.787
2014 Sauteur L, Krudewig A, Herwig L, Ehrenfeuchter N, Lenard A, Affolter M, Belting HG. Cdh5/VE-cadherin promotes endothelial cell interface elongation via cortical actin polymerization during angiogenic sprouting. Cell Reports. 9: 504-13. PMID 25373898 DOI: 10.1016/j.celrep.2014.09.024  0.381
2014 Santos ME, Braasch I, Boileau N, Meyer BS, Sauteur L, Böhne A, Belting HG, Affolter M, Salzburger W. The evolution of cichlid fish egg-spots is linked with a cis-regulatory change. Nature Communications. 5: 5149. PMID 25296686 DOI: 10.1038/Ncomms6149  0.324
2014 De Smet F, Tembuyser B, Lenard A, Claes F, Zhang J, Michielsen C, Van Schepdael A, Herbert JM, Bono F, Affolter M, Dewerchin M, Carmeliet P. Fibroblast growth factor signaling affects vascular outgrowth and is required for the maintenance of blood vessel integrity. Chemistry & Biology. 21: 1310-7. PMID 25200605 DOI: 10.1016/j.chembiol.2014.07.018  0.331
2014 Hamaratoglu F, Affolter M, Pyrowolakis G. Dpp/BMP signaling in flies: from molecules to biology. Seminars in Cell & Developmental Biology. 32: 128-36. PMID 24813173 DOI: 10.1016/J.Semcdb.2014.04.036  0.774
2014 Hultin S, Zheng Y, Mojallal M, Vertuani S, Gentili C, Balland M, Milloud R, Belting HG, Affolter M, Helker CS, Adams RH, Herzog W, Uhlen P, Majumdar A, Holmgren L. AmotL2 links VE-cadherin to contractile actin fibres necessary for aortic lumen expansion. Nature Communications. 5: 3743. PMID 24806444 DOI: 10.1038/Ncomms4743  0.37
2014 Kanca O, Ochoa-Espinosa A, Affolter M. IV. Tools and methods for studying cell migration and cell rearrangement in tissue and organ development. Methods (San Diego, Calif.). 68: 228-32. PMID 24631575 DOI: 10.1016/J.Ymeth.2014.03.004  0.786
2014 Kanca O, Caussinus E, Denes AS, Percival-Smith A, Affolter M. Raeppli: a whole-tissue labeling tool for live imaging of Drosophila development. Development (Cambridge, England). 141: 472-80. PMID 24335257 DOI: 10.1242/Dev.102913  0.692
2013 Caussinus E, Kanca O, Affolter M. Protein knockouts in living eukaryotes using deGradFP and green fluorescent protein fusion targets. Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.]. 73: Unit 30.2. PMID 24510595 DOI: 10.1002/0471140864.Ps3002S73  0.688
2013 Lenard A, Affolter M. Tugging organs into place. Developmental Cell. 27: 243-4. PMID 24229640 DOI: 10.1016/j.devcel.2013.10.021  0.334
2013 Lenard A, Ellertsdottir E, Herwig L, Krudewig A, Sauteur L, Belting HG, Affolter M. In vivo analysis reveals a highly stereotypic morphogenetic pathway of vascular anastomosis. Developmental Cell. 25: 492-506. PMID 23763948 DOI: 10.1016/j.devcel.2013.05.010  0.371
2013 Helker CS, Schuermann A, Karpanen T, Zeuschner D, Belting HG, Affolter M, Schulte-Merker S, Herzog W. The zebrafish common cardinal veins develop by a novel mechanism: lumen ensheathment. Development (Cambridge, England). 140: 2776-86. PMID 23698350 DOI: 10.1242/dev.091876  0.325
2013 Siekmann AF, Affolter M, Belting HG. The tip cell concept 10 years after: new players tune in for a common theme. Experimental Cell Research. 319: 1255-63. PMID 23419245 DOI: 10.1016/j.yexcr.2013.01.019  0.341
2012 Baer MM, Palm W, Eaton S, Leptin M, Affolter M. Microsomal triacylglycerol transfer protein (MTP) is required to expand tracheal lumen in Drosophila in a cell-autonomous manner. Journal of Cell Science. 125: 6038-48. PMID 23132924 DOI: 10.1242/Dev.096248  0.355
2012 Ellertsdottir E, Berthold PR, Bouzaffour M, Dufourcq P, Trayer V, Gauron C, Vriz S, Affolter M, Rampon C. Developmental role of zebrafish protease-activated receptor 1 (PAR1) in the cardio-vascular system. Plos One. 7: e42131. PMID 22860064 DOI: 10.1371/journal.pone.0042131  0.374
2012 Ochoa-Espinosa A, Affolter M. Branching morphogenesis: from cells to organs and back. Cold Spring Harbor Perspectives in Biology. 4. PMID 22798543 DOI: 10.1101/Cshperspect.A008243  0.774
2012 Ochoa-Espinosa A, Baer MM, Affolter M. Tubulogenesis: Src42A goes to great lengths in tube elongation. Current Biology : Cb. 22: R446-9. PMID 22677286 DOI: 10.1016/J.Cub.2012.04.033  0.772
2012 Wang S, Meyer H, Ochoa-Espinosa A, Buchwald U, Onel S, Altenhein B, Heinisch JJ, Affolter M, Paululat A. GBF1 (Gartenzwerg)-dependent secretion is required for Drosophila tubulogenesis. Journal of Cell Science. 125: 461-72. PMID 22302994 DOI: 10.1242/Jcs.092551  0.788
2012 Caussinus E, Kanca O, Affolter M. Fluorescent fusion protein knockout mediated by anti-GFP nanobody. Nature Structural & Molecular Biology. 19: 117-21. PMID 22157958 DOI: 10.1038/Nsmb.2180  0.692
2011 Herwig L, Blum Y, Krudewig A, Ellertsdottir E, Lenard A, Belting HG, Affolter M. Distinct cellular mechanisms of blood vessel fusion in the zebrafish embryo. Current Biology : Cb. 21: 1942-8. PMID 22079115 DOI: 10.1016/j.cub.2011.10.016  0.353
2011 Hamaratoglu F, de Lachapelle AM, Pyrowolakis G, Bergmann S, Affolter M. Dpp signaling activity requires Pentagone to scale with tissue size in the growing Drosophila wing imaginal disc. Plos Biology. 9: e1001182. PMID 22039350 DOI: 10.1371/Journal.Pbio.1001182  0.76
2011 Totong R, Schell T, Lescroart F, Ryckebüsch L, Lin YF, Zygmunt T, Herwig L, Krudewig A, Gershoony D, Belting HG, Affolter M, Torres-Vázquez J, Yelon D. The novel transmembrane protein Tmem2 is essential for coordination of myocardial and endocardial morphogenesis. Development (Cambridge, England). 138: 4199-205. PMID 21896630 DOI: 10.1242/Dev.064261  0.361
2011 Schulz JG, Ceulemans H, Caussinus E, Baietti MF, Affolter M, Hassan BA, David G. Drosophila syndecan regulates tracheal cell migration by stabilizing Robo levels. Embo Reports. 12: 1039-46. PMID 21836636 DOI: 10.1038/embor.2011.153  0.433
2011 Schwank G, Dalessi S, Yang SF, Yagi R, de Lachapelle AM, Affolter M, Bergmann S, Basler K. Formation of the long range Dpp morphogen gradient. Plos Biology. 9: e1001111. PMID 21814489 DOI: 10.1371/journal.pbio.1001111  0.316
2011 Affolter M, Basler K. Cell biology. Cytonemes show their colors. Science (New York, N.Y.). 332: 312-3. PMID 21493848 DOI: 10.1126/science.1205971  0.389
2011 Vuilleumier R, Affolter M, Pyrowolakis G. Pentagone: patrolling BMP morphogen signaling. Fly. 5: 210-4. PMID 21406970 DOI: 10.4161/Fly.5.3.15311  0.386
2011 Oggier DM, Lenard A, Küry M, Hoeger B, Affolter M, Fent K. Effects of the protein kinase inhibitor PKC412 on gene expression and link to physiological effects in zebrafish Danio rerio eleuthero-embryos. Toxicological Sciences : An Official Journal of the Society of Toxicology. 119: 104-15. PMID 20980353 DOI: 10.1093/toxsci/kfq330  0.34
2011 Zygmunt T, Gay CM, Blondelle J, Flaherty KM, Means PC, Herwig L, Krudewig A, Belting H, Affolter M, Torres-Vazquez J. Beyond guidance: A novel role for Sema–PlxnD1 signaling in vascular development Developmental Biology. 356: 102. DOI: 10.1016/J.Ydbio.2011.05.009  0.303
2010 Vuilleumier R, Springhorn A, Patterson L, Koidl S, Hammerschmidt M, Affolter M, Pyrowolakis G. Control of Dpp morphogen signalling by a secreted feedback regulator. Nature Cell Biology. 12: 611-7. PMID 20453847 DOI: 10.1038/Ncb2064  0.422
2010 Chanut-Delalande H, Jung AC, Baer MM, Lin L, Payre F, Affolter M. The Hrs/Stam complex acts as a positive and negative regulator of RTK signaling during Drosophila development. Plos One. 5: e10245. PMID 20422006 DOI: 10.1371/journal.pone.0010245  0.396
2010 Ninov N, Menezes-Cabral S, Prat-Rojo C, Manjón C, Weiss A, Pyrowolakis G, Affolter M, Martín-Blanco E. Dpp signaling directs cell motility and invasiveness during epithelial morphogenesis. Current Biology : Cb. 20: 513-20. PMID 20226662 DOI: 10.1016/j.cub.2010.01.063  0.407
2010 Fernandes I, Chanut-Delalande H, Ferrer P, Latapie Y, Waltzer L, Affolter M, Payre F, Plaza S. Zona pellucida domain proteins remodel the apical compartment for localized cell shape changes. Developmental Cell. 18: 64-76. PMID 20152178 DOI: 10.1016/j.devcel.2009.11.009  0.404
2010 Weiss A, Charbonnier E, Ellertsdóttir E, Tsirigos A, Wolf C, Schuh R, Pyrowolakis G, Affolter M. A conserved activation element in BMP signaling during Drosophila development. Nature Structural & Molecular Biology. 17: 69-76. PMID 20010841 DOI: 10.1038/Nsmb.1715  0.377
2010 Baer MM, Bilstein A, Caussinus E, Csiszar A, Affolter M, Leptin M. The role of apoptosis in shaping the tracheal system in the Drosophila embryo. Mechanisms of Development. 127: 28-35. PMID 19995601 DOI: 10.1016/j.mod.2009.11.003  0.374
2010 Ellertsdóttir E, Lenard A, Blum Y, Krudewig A, Herwig L, Affolter M, Belting HG. Vascular morphogenesis in the zebrafish embryo. Developmental Biology. 341: 56-65. PMID 19895803 DOI: 10.1016/j.ydbio.2009.10.035  0.366
2010 Li K, Blum Y, Verma A, Liu Z, Pramanik K, Leigh NR, Chun CZ, Samant GV, Zhao B, Garnaas MK, Horswill MA, Stanhope SA, North PE, Miao RQ, Wilkinson GA, ... Affolter M, et al. A noncoding antisense RNA in tie-1 locus regulates tie-1 function in vivo. Blood. 115: 133-9. PMID 19880500 DOI: 10.1182/Blood-2009-09-242180  0.315
2009 Affolter M, Zeller R, Caussinus E. Tissue remodelling through branching morphogenesis. Nature Reviews. Molecular Cell Biology. 10: 831-42. PMID 19888266 DOI: 10.1038/Nrm2797  0.379
2009 Hamaratoglu F, Basler K, Affolter M. Confronting morphogen gradients: how important are they for growth? Science Signaling. 2: pe67. PMID 19861687 DOI: 10.1126/Scisignal.294Pe67  0.74
2009 Baer MM, Chanut-Delalande H, Affolter M. Cellular and molecular mechanisms underlying the formation of biological tubes. Current Topics in Developmental Biology. 89: 137-62. PMID 19737645 DOI: 10.1016/S0070-2153(09)89006-6  0.323
2009 Grieder NC, Morata G, Affolter M, Gehring WJ. Spalt major controls the development of the notum and of wing hinge primordia of the Drosophila melanogaster wing imaginal disc. Developmental Biology. 329: 315-26. PMID 19298807 DOI: 10.1016/j.ydbio.2009.03.006  0.575
2009 Kleaveland B, Zheng X, Liu JJ, Blum Y, Tung JJ, Zou Z, Sweeney SM, Chen M, Guo L, Lu MM, Zhou D, Kitajewski J, Affolter M, Ginsberg MH, Kahn ML. Regulation of cardiovascular development and integrity by the heart of glass-cerebral cavernous malformation protein pathway. Nature Medicine. 15: 169-76. PMID 19151727 DOI: 10.1038/Nm.1918  0.354
2009 Ninov N, Manjon C, Cabral S, Weiss A, Pyrowolakis G, Affolter M, Martin-Blanco E, Prat CR. 20-P031 Dpp signalling directs cell motility and invasiveness during epithelial morphogenesis Mechanisms of Development. 126: S313. DOI: 10.1016/j.mod.2009.06.864  0.322
2009 Charbonnier E, Weiss A, Affolter M, Pyrowolakis G. 13-P123 Regulation of BMP signaling pathway in Drosophila melanogaster Mechanisms of Development. 126: S232. DOI: 10.1016/j.mod.2009.06.596  0.319
2008 Caussinus E, Colombelli J, Affolter M. Tip-cell migration controls stalk-cell intercalation during Drosophila tracheal tube elongation. Current Biology : Cb. 18: 1727-34. PMID 19026547 DOI: 10.1016/j.cub.2008.10.062  0.39
2008 Grieder NC, Caussinus E, Parker DS, Cadigan K, Affolter M, Luschnig S. gammaCOP is required for apical protein secretion and epithelial morphogenesis in Drosophila melanogaster. Plos One. 3: e3241. PMID 18802472 DOI: 10.1371/Journal.Pone.0003241  0.706
2008 Affolter M, Pyrowolakis G, Weiss A, Basler K. Signal-induced repression: the exception or the rule in developmental signaling? Developmental Cell. 15: 11-22. PMID 18606137 DOI: 10.1016/j.devcel.2008.06.006  0.38
2008 Affolter M, Caussinus E. Tracheal branching morphogenesis in Drosophila: new insights into cell behaviour and organ architecture. Development (Cambridge, England). 135: 2055-64. PMID 18480161 DOI: 10.1242/dev.014498  0.399
2008 Blum Y, Belting HG, Ellertsdottir E, Herwig L, Lüders F, Affolter M. Complex cell rearrangements during intersegmental vessel sprouting and vessel fusion in the zebrafish embryo. Developmental Biology. 316: 312-22. PMID 18342303 DOI: 10.1016/j.ydbio.2008.01.038  0.372
2008 Gohl D, Müller M, Pirrotta V, Affolter M, Schedl P. Enhancer blocking and transvection at the Drosophila apterous locus. Genetics. 178: 127-43. PMID 18202363 DOI: 10.1534/Genetics.107.077768  0.682
2007 Merabet S, Saadaoui M, Sambrani N, Hudry B, Pradel J, Affolter M, Graba Y. A unique Extradenticle recruitment mode in the Drosophila Hox protein Ultrabithorax. Proceedings of the National Academy of Sciences of the United States of America. 104: 16946-51. PMID 17942685 DOI: 10.1073/pnas.0705832104  0.362
2007 Affolter M, Basler K. The Decapentaplegic morphogen gradient: from pattern formation to growth regulation. Nature Reviews. Genetics. 8: 663-74. PMID 17703237 DOI: 10.1038/nrg2166  0.345
2007 Chanut-Delalande H, Jung AC, Lin L, Baer MM, Bilstein A, Cabernard C, Leptin M, Affolter M. A genetic mosaic analysis with a repressible cell marker screen to identify genes involved in tracheal cell migration during Drosophila air sac morphogenesis. Genetics. 176: 2177-87. PMID 17603108 DOI: 10.1534/Genetics.107.073890  0.743
2006 Affolter M, Pyrowolakis G. eIF4A goes beyond translation. Nature Cell Biology. 8: 1319-21. PMID 17139280 DOI: 10.1038/ncb1206-1319  0.308
2006 Cordier F, Hartmann B, Rogowski M, Affolter M, Grzesiek S. DNA recognition by the brinker repressor--an extreme case of coupling between binding and folding. Journal of Molecular Biology. 361: 659-72. PMID 16876822 DOI: 10.1016/j.jmb.2006.06.045  0.301
2006 Affolter M, Mann R. Hyped-up for Hox in Hyderabad. Workshop on upstream and downstream of Hox genes. Embo Reports. 7: 674-8. PMID 16799462 DOI: 10.1038/sj.embor.7400734  0.336
2006 Jung AC, Ribeiro C, Michaut L, Certa U, Affolter M. Polychaetoid/ZO-1 is required for cell specification and rearrangement during Drosophila tracheal morphogenesis. Current Biology : Cb. 16: 1224-31. PMID 16782014 DOI: 10.1016/j.cub.2006.04.048  0.608
2006 Neumann M, Affolter M. Remodelling epithelial tubes through cell rearrangements: from cells to molecules. Embo Reports. 7: 36-40. PMID 16391535 DOI: 10.1038/sj.embor.7400597  0.372
2005 Cabernard C, Affolter M. Distinct roles for two receptor tyrosine kinases in epithelial branching morphogenesis in Drosophila. Developmental Cell. 9: 831-42. PMID 16326394 DOI: 10.1016/J.Devcel.2005.10.008  0.742
2005 Merabet S, Ebner A, Affolter M. The Drosophila Extradenticle and Homothorax selector proteins control branchless/FGF expression in mesodermal bridge-cells. Embo Reports. 6: 762-8. PMID 16007069 DOI: 10.1038/sj.embor.7400462  0.416
2005 Affolter M, Weijer CJ. Signaling to cytoskeletal dynamics during chemotaxis. Developmental Cell. 9: 19-34. PMID 15992538 DOI: 10.1016/j.devcel.2005.06.003  0.34
2005 Ebner A, Cabernard C, Affolter M, Merabet S. Recognition of distinct target sites by a unique Labial/Extradenticle/Homothorax complex. Development (Cambridge, England). 132: 1591-600. PMID 15753213 DOI: 10.1242/Dev.01721  0.718
2005 Jung AC, Denholm B, Skaer H, Affolter M. Renal tubule development in Drosophila: a closer look at the cellular level. Journal of the American Society of Nephrology : Jasn. 16: 322-8. PMID 15647336 DOI: 10.1681/Asn.2004090729  0.39
2004 Ribeiro C, Neumann M, Affolter M. Genetic control of cell intercalation during tracheal morphogenesis in Drosophila. Current Biology : Cb. 14: 2197-207. PMID 15620646 DOI: 10.1016/j.cub.2004.11.056  0.604
2004 Cabernard C, Neumann M, Affolter M. Cellular and molecular mechanisms involved in branching morphogenesis of the Drosophila tracheal system. Journal of Applied Physiology (Bethesda, Md. : 1985). 97: 2347-53. PMID 15531575 DOI: 10.1152/Japplphysiol.00435.2004  0.714
2004 Pyrowolakis G, Hartmann B, Müller B, Basler K, Affolter M. A simple molecular complex mediates widespread BMP-induced repression during Drosophila development. Developmental Cell. 7: 229-40. PMID 15296719 DOI: 10.1016/j.devcel.2004.07.008  0.449
2004 Leptin M, Affolter M. Drosophila gastrulation: identification of a missing link. Current Biology : Cb. 14: R480-2. PMID 15203022 DOI: 10.1016/j.cub.2004.06.016  0.309
2004 Jaźwińska A, Affolter M. A family of genes encoding zona pellucida (ZP) domain proteins is expressed in various epithelial tissues during Drosophila embryogenesis. Gene Expression Patterns : Gep. 4: 413-21. PMID 15183308 DOI: 10.1016/j.modgep.2004.01.003  0.373
2004 Petit V, Nussbaumer U, Dossenbach C, Affolter M. Downstream-of-FGFR is a fibroblast growth factor-specific scaffolding protein and recruits Corkscrew upon receptor activation. Molecular and Cellular Biology. 24: 3769-81. PMID 15082772 DOI: 10.1128/MCB.24.9.3769-3781.2004  0.42
2003 Ja?wi?ska A, Ribeiro C, Affolter M. Epithelial tube morphogenesis during Drosophila tracheal development requires Piopio, a luminal ZP protein. Nature Cell Biology. 5: 895-901. PMID 12973360 DOI: 10.1038/ncb1049  0.586
2003 Groppe J, Greenwald J, Wiater E, Rodriguez-Leon J, Economides AN, Kwiatkowski W, Baban K, Affolter M, Vale WW, Izpisua Belmonte JC, Choe S. Structural basis of BMP signaling inhibition by Noggin, a novel twelve-membered cystine knot protein. The Journal of Bone and Joint Surgery. American Volume. 85: 52-8. PMID 12925610 DOI: 10.2106/00004623-200300003-00010  0.359
2003 Ribeiro C, Petit V, Affolter M. Signaling systems, guided cell migration, and organogenesis: insights from genetic studies in Drosophila. Developmental Biology. 260: 1-8. PMID 12885551 DOI: 10.1016/S0012-1606(03)00211-2  0.589
2003 Müller B, Hartmann B, Pyrowolakis G, Affolter M, Basler K. Conversion of an extracellular Dpp/BMP morphogen gradient into an inverse transcriptional gradient. Cell. 113: 221-33. PMID 12705870 DOI: 10.1016/S0092-8674(03)00241-1  0.431
2003 Affolter M, Bellusci S, Itoh N, Shilo B, Thiery JP, Werb Z. Tube or not tube: remodeling epithelial tissues by branching morphogenesis. Developmental Cell. 4: 11-8. PMID 12530959 DOI: 10.1016/S1534-5807(02)00410-0  0.329
2002 Groppe J, Greenwald J, Wiater E, Rodriguez-Leon J, Economides AN, Kwiatkowski W, Affolter M, Vale WW, Izpisua Belmonte JC, Choe S. Structural basis of BMP signalling inhibition by the cystine knot protein Noggin. Nature. 420: 636-42. PMID 12478285 DOI: 10.1038/Nature01245  0.345
2002 Ribeiro C, Ebner A, Affolter M. In vivo imaging reveals different cellular functions for FGF and Dpp signaling in tracheal branching morphogenesis. Developmental Cell. 2: 677-83. PMID 12015974 DOI: 10.1016/S1534-5807(02)00171-5  0.579
2002 Ebner A, Kiefer FN, Ribeiro C, Petit V, Nussbaumer U, Affolter M. Tracheal development in Drosophila melanogaster as a model system for studying the development of a branched organ. Gene. 287: 55-66. PMID 11992723 DOI: 10.1016/S0378-1119(01)00895-2  0.587
2002 Petit V, Ribeiro C, Ebner A, Affolter M. Regulation of cell migration during tracheal development in Drosophila melanogaster. The International Journal of Developmental Biology. 46: 125-32. PMID 11902673 DOI: 10.1387/Ijdb.11902673  0.583
2002 Streit A, Kohler R, Marty T, Belfiore M, Takacs-Vellai K, Vigano MA, Schnabel R, Affolter M, Müller F. Conserved regulation of the Caenorhabditis elegans labial/Hox1 gene ceh-13. Developmental Biology. 242: 96-108. PMID 11820809 DOI: 10.1006/Dbio.2001.0544  0.746
2001 Marty T, Vigano MA, Ribeiro C, Nussbaumer U, Grieder NC, Affolter M. A HOX complex, a repressor element and a 50 bp sequence confer regional specificity to a DPP-responsive enhancer. Development (Cambridge, England). 128: 2833-45. PMID 11526088  0.758
2001 Affolter M, Marty T, Vigano MA, Ja?wi?ska A. Nuclear interpretation of Dpp signaling in Drosophila. The Embo Journal. 20: 3298-305. PMID 11432817 DOI: 10.1093/Emboj/20.13.3298  0.743
2000 Sivasankaran R, Vigano MA, Müller B, Affolter M, Basler K. Direct transcriptional control of the Dpp target omb by the DNA binding protein Brinker. The Embo Journal. 19: 6162-72. PMID 11080162 DOI: 10.1093/emboj/19.22.6162  0.371
2000 Affolter M, Shilo BZ. Genetic control of branching morphogenesis during Drosophila tracheal development Current Opinion in Cell Biology. 12: 731-735. PMID 11063940 DOI: 10.1016/S0955-0674(00)00160-5  0.347
2000 Marty T, Müller B, Basler K, Affolter M. Schnurri mediates Dpp-dependent repression of brinker transcription. Nature Cell Biology. 2: 745-9. PMID 11025666 DOI: 10.1038/35036383  0.745
2000 Nussbaumer U, Halder G, Groppe J, Affolter M, Montagne J. Expression of the blistered/DSRF gene is controlled by different morphogens during Drosophila trachea and wing development. Mechanisms of Development. 96: 27-36. PMID 10940622 DOI: 10.1016/S0925-4773(00)00373-7  0.62
2000 Udagawa Y, Hanai JI, Tada KI, Grieder NC, Momoeda M, Taketani Y, Affolter M, Kawabata M, Miyazono K. Schnurri interacts with Mad in a Dpp-dependent manner Genes to Cells. 5: 359-369. PMID 10886364 DOI: 10.1046/j.1365-2443.2000.00328.x  0.405
1999 Ryoo HD, Marty T, Casares F, Affolter M, Mann RS. Regulation of Hox target genes by a DNA bound Homothorax/Hox/Extradenticle complex. Development (Cambridge, England). 126: 5137-48. PMID 10529430  0.714
1999 Affolter M, Marty T, Vigano MA. Balancing import and export in development. Genes & Development. 13: 913-5. PMID 10215619 DOI: 10.1101/Gad.13.8.913  0.697
1998 Chen CK, Kühnlein RP, Eulenberg KG, Vincent S, Affolter M, Schuh R. The transcription factors KNIRPS and KNIRPS RELATED control cell migration and branch morphogenesis during Drosophila tracheal development. Development (Cambridge, England). 125: 4959-68. PMID 9811580  0.559
1998 Vincent S, Wilson R, Coelho C, Affolter M, Leptin M. The Drosophila protein Dof is specifically required for FGF signaling. Molecular Cell. 2: 515-25. PMID 9809073 DOI: 10.1016/S1097-2765(00)80151-3  0.542
1998 Groppe J, Rumpel K, Economides AN, Stahl N, Sebald W, Affolter M. Biochemical and biophysical characterization of refolded Drosophila DPP, a homolog of bone morphogenetic proteins 2 and 4 Journal of Biological Chemistry. 273: 29052-29065. PMID 9786911 DOI: 10.1074/Jbc.273.44.29052  0.333
1998 Mann RS, Affolter M. Hox proteins meet more partners. Current Opinion in Genetics & Development. 8: 423-9. PMID 9729718 DOI: 10.1016/S0959-437X(98)80113-5  0.402
1998 Brodbeck D, Amherd R, Callaerts P, Hintermann E, Meyer UA, Affolter M. Molecular and biochemical characterization of the aaNAT1 (Dat) locus in Drosophila melanogaster: differential expression of two gene products. Dna and Cell Biology. 17: 621-33. PMID 9703021 DOI: 10.1089/Dna.1998.17.621  0.629
1997 Grieder NC, Marty T, Ryoo HD, Mann RS, Affolter M. Synergistic activation of a Drosophila enhancer by HOM/EXD and DPP signaling. The Embo Journal. 16: 7402-10. PMID 9405369 DOI: 10.1093/Emboj/16.24.7402  0.742
1997 Yamamoto Y, Girard F, Bello B, Affolter M, Gehring WJ. The cramped gene of Drosophila is a member of the Polycomb-group, and interacts with mus209, the gene encoding Proliferating Cell Nuclear Antigen. Development (Cambridge, England). 124: 3385-94. PMID 9310333  0.512
1997 Vincent S, Ruberte E, Grieder NC, Chen CK, Haerry T, Schuh R, Affolter M. DPP controls tracheal cell migration along the dorsoventral body axis of the Drosophila embryo. Development (Cambridge, England). 124: 2741-50. PMID 9226445  0.529
1996 Montagne J, Groppe J, Guillemin K, Krasnow MA, Gehring WJ, Affolter M. The Drosophila Serum Response Factor gene is required for the formation of intervein tissue of the wing and is allelic to blistered. Development (Cambridge, England). 122: 2589-97. PMID 8787734  0.533
1996 Guillemin K, Groppe J, Ducker K, Treisman R, Hafen E, Affolter M, Krasnow MA. The pruned gene encodes the Drosophila serum response factor and regulates cytoplasmic outgrowth during terminal branching of the tracheal system. Development (Cambridge, England). 122: 1353-62. PMID 8625824 DOI: 10.5167/Uzh-664  0.624
1995 Grieder NC, Nellen D, Burke R, Basler K, Affolter M. schnurri is required for drosophila Dpp signaling and encodes a zinc finger protein similar to the mammalian transcription factor PRDII-BF1 Cell. 81: 791-800. PMID 7774018 DOI: 10.1016/0092-8674(95)90540-5  0.398
1995 Ruberte E, Marty T, Nellen D, Affolter M, Basler K. An absolute requirement for both the type II and type I receptors, punt and thick veins, for dpp signaling in vivo. Cell. 80: 889-97. PMID 7697719 DOI: 10.1016/0092-8674(95)90292-9  0.703
1994 Nellen D, Affolter M, Basler K. Receptor serine/threonine kinases implicated in the control of Drosophila body pattern by decapentaplegic Cell. 78: 225-237. PMID 8044837 DOI: 10.1016/0092-8674(94)90293-3  0.34
1994 Gehring WJ, Qian YQ, Billeter M, Furukubo-Tokunaga K, Schier AF, Resendez-Perez D, Affolter M, Otting G, Wüthrich K. Homeodomain-DNA recognition. Cell. 78: 211-23. PMID 8044836 DOI: 10.1016/0092-8674(94)90292-5  0.747
1994 Gehring WJ, Affolter M, Bürglin T. Homeodomain proteins. Annual Review of Biochemistry. 63: 487-526. PMID 7979246 DOI: 10.1146/annurev.bi.63.070194.002415  0.424
1994 Dorn A, Affolter M, Gehring WJ, Leupin W. Homeodomain proteins in development and therapy. Pharmacology & Therapeutics. 61: 155-84. PMID 7938169 DOI: 10.1016/0163-7258(94)90061-2  0.559
1994 Affolter M, Nellen D, Nussbaumer U, Basler K. Multiple requirements for the receptor serine/threonine kinase thick veins reveal novel functions of TGFβ homologs during Drosophila embryogenesis Development. 120: 3105-3117. PMID 7720555 DOI: 10.5167/Uzh-1050  0.4
1994 Affolter M, Montagne J, Walldorf U, Groppe J, Kloter U, LaRosa M, Gehring WJ. The Drosophila SRF homolog is expressed in a subset of tracheal cells and maps within a genomic region required for tracheal development. Development (Cambridge, England). 120: 743-53. PMID 7600954  0.546
1993 Affolter M, Walldorf U, Kloter U, Schier AF, Gehring WJ. Regional repression of a Drosophila POU box gene in the endoderm involves inductive interactions between germ layers. Development (Cambridge, England). 117: 1199-210. PMID 8104774  0.642
1992 Qian YQ, Otting G, Furukubo-Tokunaga K, Affolter M, Gehring WJ, Wüthrich K. NMR structure determination reveals that the homeodomain is connected through a flexible linker to the main body in the Drosophila Antennapedia protein. Proceedings of the National Academy of Sciences of the United States of America. 89: 10738-42. PMID 1359544 DOI: 10.1073/PNAS.89.22.10738  0.739
1992 Furukubo-Tokunaga K, Müller M, Affolter M, Pick L, Kloter U, Gehring WJ. In vivo analysis of the helix-turn-helix motif of the fushi tarazu homeo domain of Drosophila melanogaster. Genes & Development. 6: 1082-96. PMID 1350560 DOI: 10.1101/Gad.6.6.1082  0.75
1992 Dorn A, Affolter M, Müller M, Gehring WJ, Leupin W. Distamycin-induced inhibition of homeodomain-DNA complexes. The Embo Journal. 11: 279-86. PMID 1346762 DOI: 10.1002/J.1460-2075.1992.Tb05050.X  0.482
1991 Affolter M, Percival-Smith A, Müller M, Billeter M, Qian YQ, Otting G, Wüthrich K, Gehring WJ. Similarities between the homeodomain and the Hin recombinase DNA-binding domain. Cell. 64: 879-80. PMID 2001587 DOI: 10.1016/0092-8674(91)90311-L  0.479
1990 Gehring WJ, Müller M, Affolter M, Percival-Smith A, Billeter M, Qian YQ, Otting G, Wüthrich K. The structure of the homeodomain and its functional implications. Trends in Genetics : Tig. 6: 323-9. PMID 1980756 DOI: 10.1016/0168-9525(90)90253-3  0.516
1990 Percival-Smith A, Müller M, Affolter M, Gehring WJ. The interaction with DNA of wild-type and mutant fushi tarazu homeodomains. The Embo Journal. 9: 3967-74. PMID 1979032 DOI: 10.1002/J.1460-2075.1990.Tb07617.X  0.492
1990 Pick L, Schier A, Affolter M, Schmidt-Glenewinkel T, Gehring WJ. Analysis of the ftz upstream element: germ layer-specific enhancers are independently autoregulated. Genes & Development. 4: 1224-39. PMID 1976571 DOI: 10.1101/GAD.4.7.1224  0.658
1990 Otting G, Qian YQ, Billeter M, Müller M, Affolter M, Gehring WJ, Wüthrich K. Protein--DNA contacts in the structure of a homeodomain--DNA complex determined by nuclear magnetic resonance spectroscopy in solution. The Embo Journal. 9: 3085-92. PMID 1976507 DOI: 10.1002/J.1460-2075.1990.Tb07505.X  0.502
1990 Affolter M, Schier A, Gehring WJ. Homeodomain proteins and the regulation of gene expression. Current Opinion in Cell Biology. 2: 485-95. PMID 1974141 DOI: 10.1016/0955-0674(90)90132-X  0.647
1990 Affolter M, Percival-Smith A, Müller M, Leupin W, Gehring WJ. DNA binding properties of the purified Antennapedia homeodomain. Proceedings of the National Academy of Sciences of the United States of America. 87: 4093-7. PMID 1971945 DOI: 10.1073/Pnas.87.11.4093  0.493
1989 Gehring W, Müller M, Affolter M. Structure and function of the homeodomain Cell Differentiation and Development. 27: 166. DOI: 10.1016/0922-3371(89)90512-1  0.509
1988 Otting G, Qian YQ, Müller M, Affolter M, Gehring W, Wüthrich K. Secondary structure determination for the Antennapedia homeodomain by nuclear magnetic resonance and evidence for a helix-turn-helix motif. The Embo Journal. 7: 4305-9. PMID 2907480 DOI: 10.1002/J.1460-2075.1988.Tb03329.X  0.496
1988 Müller M, Affolter M, Leupin W, Otting G, Wüthrich K, Gehring WJ. Isolation and sequence-specific DNA binding of the Antennapedia homeodomain. The Embo Journal. 7: 4299-304. PMID 2907479 DOI: 10.1002/J.1460-2075.1988.Tb03328.X  0.507
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