Eran Segal, Ph.D. - Publications

Affiliations: 
2004 Stanford University, Palo Alto, CA 

119 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Suez J, Zmora N, Zilberman-Schapira G, Mor U, Dori-Bachash M, Bashiardes S, Zur M, Regev-Lehavi D, Ben-Zeev Brik R, Federici S, Horn M, Cohen Y, Moor AE, Zeevi D, Korem T, ... ... Segal E, et al. Post-Antibiotic Gut Mucosal Microbiome Reconstitution Is Impaired by Probiotics and Improved by Autologous FMT. Cell. 174: 1406-1423.e16. PMID 30193113 DOI: 10.1016/j.cell.2018.08.047  0.36
2018 Kotler E, Shani O, Goldfeld G, Lotan-Pompan M, Tarcic O, Gershoni A, Hopf TA, Marks DS, Oren M, Segal E. A Systematic p53 Mutation Library Links Differential Functional Impact to Cancer Mutation Pattern and Evolutionary Conservation. Molecular Cell. 71: 873. PMID 30193102 DOI: 10.1016/j.molcel.2018.08.013  0.36
2018 Kotler E, Shani O, Goldfeld G, Lotan-Pompan M, Tarcic O, Gershoni A, Hopf TA, Marks DS, Oren M, Segal E. A Systematic p53 Mutation Library Links Differential Functional Impact to Cancer Mutation Pattern and Evolutionary Conservation. Molecular Cell. 71: 178-190.e8. PMID 29979965 DOI: 10.1016/j.molcel.2018.06.012  0.36
2018 Rothschild D, Weissbrod O, Barkan E, Kurilshikov A, Korem T, Zeevi D, Costea PI, Godneva A, Kalka IN, Bar N, Shilo S, Lador D, Vila AV, Zmora N, Pevsner-Fischer M, ... ... Segal E, et al. Environment dominates over host genetics in shaping human gut microbiota. Nature. PMID 29489753 DOI: 10.1038/nature25973  0.48
2018 Vainberg Slutskin I, Weingarten-Gabbay S, Nir R, Weinberger A, Segal E. Unraveling the determinants of microRNA mediated regulation using a massively parallel reporter assay. Nature Communications. 9: 529. PMID 29410437 DOI: 10.1038/s41467-018-02980-z  0.48
2017 Korem T, Zeevi D, Zmora N, Weissbrod O, Bar N, Lotan-Pompan M, Avnit-Sagi T, Kosower N, Malka G, Rein M, Suez J, Goldberg BZ, Weinberger A, Levy AA, Elinav E, ... Segal E, et al. Bread Affects Clinical Parameters and Induces Gut Microbiome-Associated Personal Glycemic Responses. Cell Metabolism. 25: 1243-1253.e5. PMID 28591632 DOI: 10.1016/j.cmet.2017.05.002  0.48
2017 Rowan S, Jiang S, Korem T, Szymanski J, Chang ML, Szelog J, Cassalman C, Dasuri K, McGuire C, Nagai R, Du XL, Brownlee M, Rabbani N, Thornalley PJ, Baleja JD, ... ... Segal E, et al. Involvement of a gut-retina axis in protection against dietary glycemia-induced age-related macular degeneration. Proceedings of the National Academy of Sciences of the United States of America. PMID 28507131 DOI: 10.1073/pnas.1702302114  0.48
2017 van Dijk D, Sharon E, Lotan-Pompan M, Weinberger A, Segal E, Carey LB. Corrigendum: Large-scale mapping of gene regulatory logic reveals context-dependent repression by transcriptional activators. Genome Research. 27: 500. PMID 28250019 DOI: 10.1101/gr.220574.117  0.48
2017 Levo M, Avnit-Sagi T, Lotan-Pompan M, Kalma Y, Weinberger A, Yakhini Z, Segal E. Systematic Investigation of Transcription Factor Activity in the Context of Chromatin Using Massively Parallel Binding and Expression Assays. Molecular Cell. 65: 604-617.e6. PMID 28212748 DOI: 10.1016/j.molcel.2017.01.007  1
2016 van Dijk D, Sharon E, Lotan-Pompan M, Weinberger A, Segal E, Carey L. Large scale mapping of gene regulatory logic reveals context dependent repression by transcriptional activators. Genome Research. PMID 27965290 DOI: 10.1101/gr.212316.116  0.48
2016 Thaiss CA, Levy M, Korem T, Dohnalová L, Shapiro H, Jaitin DA, David E, Winter DR, Gury-BenAri M, Tatirovsky E, Tuganbaev T, Federici S, Zmora N, Zeevi D, Dori-Bachash M, ... ... Segal E, et al. Microbiota Diurnal Rhythmicity Programs Host Transcriptome Oscillations. Cell. 167: 1495-1510.e12. PMID 27912059 DOI: 10.1016/j.cell.2016.11.003  0.36
2016 Keren L, Hausser J, Lotan-Pompan M, Vainberg Slutskin I, Alisar H, Kaminski S, Weinberger A, Alon U, Milo R, Segal E. Massively Parallel Interrogation of the Effects of Gene Expression Levels on Fitness. Cell. PMID 27545349 DOI: 10.1016/j.cell.2016.07.024  1
2016 Barenholz U, Keren L, Segal E, Milo R. A Minimalistic Resource Allocation Model to Explain Ubiquitous Increase in Protein Expression with Growth Rate. Plos One. 11: e0153344. PMID 27073913 DOI: 10.1371/journal.pone.0153344  1
2016 Zeevi D, Korem T, Segal E. Talking about cross-talk: the immune system and the microbiome. Genome Biology. 17: 50. PMID 26987366 DOI: 10.1186/s13059-016-0921-4  1
2016 Weingarten-Gabbay S, Elias-Kirma S, Nir R, Gritsenko AA, Stern-Ginossar N, Yakhini Z, Weinberger A, Segal E. Comparative genetics. Systematic discovery of cap-independent translation sequences in human and viral genomes. Science (New York, N.Y.). 351. PMID 26816383 DOI: 10.1126/science.aad4939  1
2016 Qu K, Garamszegi S, Wu F, Thorvaldsdottir H, Liefeld T, Ocana M, Borges-Rivera D, Pochet N, Robinson JT, Demchak B, Hull T, Ben-Artzi G, Blankenberg D, Barber GP, Lee BT, ... ... Segal E, et al. Integrative genomic analysis by interoperation of bioinformatics tools in GenomeSpace. Nature Methods. PMID 26780094 DOI: 10.1038/nmeth.3732  0.48
2016 Zmora N, Zeevi D, Korem T, Segal E, Elinav E. Taking it Personally: Personalized Utilization of the Human Microbiome in Health and Disease. Cell Host & Microbe. 19: 12-20. PMID 26764593 DOI: 10.1016/j.chom.2015.12.016  1
2015 Levy M, Thaiss CA, Zeevi D, Dohnalová L, Zilberman-Schapira G, Mahdi JA, David E, Savidor A, Korem T, Herzig Y, Pevsner-Fischer M, Shapiro H, Christ A, Harmelin A, Halpern Z, ... ... Segal E, et al. Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling. Cell. 163: 1428-43. PMID 26638072 DOI: 10.1016/j.cell.2015.10.048  1
2015 Zeevi D, Korem T, Zmora N, Israeli D, Rothschild D, Weinberger A, Ben-Yacov O, Lador D, Avnit-Sagi T, Lotan-Pompan M, Suez J, Mahdi JA, Matot E, Malka G, Kosower N, ... ... Segal E, et al. Personalized Nutrition by Prediction of Glycemic Responses. Cell. 163: 1079-94. PMID 26590418 DOI: 10.1016/j.cell.2015.11.001  1
2015 Keren L, van Dijk D, Weingarten-Gabbay S, Davidi D, Jona G, Weinberger A, Milo R, Segal E. Noise in gene expression is coupled to growth rate. Genome Research. 25: 1893-902. PMID 26355006 DOI: 10.1101/gr.191635.115  1
2015 Levo M, Zalckvar E, Sharon E, Dantas Machado AC, Kalma Y, Lotan-Pompan M, Weinberger A, Yakhini Z, Rohs R, Segal E. Corrigendum: Unraveling determinants of transcription factor binding outside the core binding site. Genome Research. 25: 1410.2. PMID 26330574 DOI: 25/9/1410.2  1
2015 Korem T, Zeevi D, Suez J, Weinberger A, Avnit-Sagi T, Pompan-Lotan M, Matot E, Jona G, Harmelin A, Cohen N, Sirota-Madi A, Thaiss CA, Pevsner-Fischer M, Sorek R, Xavier R, ... ... Segal E, et al. Growth dynamics of gut microbiota in health and disease inferred from single metagenomic samples. Science (New York, N.Y.). PMID 26229116 DOI: 10.1126/science.aac4812  1
2015 Panning B, Segal E. Editorial overview: Genome architecture and expression. Current Opinion in Genetics & Development. 31: v-vi. PMID 26051228 DOI: 10.1016/j.gde.2015.05.003  1
2015 Lubliner S, Regev I, Lotan-Pompan M, Edelheit S, Weinberger A, Segal E. Core promoter sequence in yeast is a major determinant of expression level. Genome Research. 25: 1008-17. PMID 25969468 DOI: 10.1101/gr.188193.114  1
2015 Thaiss CA, Zeevi D, Levy M, Segal E, Elinav E. A day in the life of the meta-organism: diurnal rhythms of the intestinal microbiome and its host. Gut Microbes. 6: 137-42. PMID 25901892 DOI: 10.1080/19490976.2015.1016690  0.36
2015 Shalem O, Sharon E, Lubliner S, Regev I, Lotan-Pompan M, Yakhini Z, Segal E. Systematic dissection of the sequence determinants of gene 3' end mediated expression control. Plos Genetics. 11: e1005147. PMID 25875337 DOI: 10.1371/journal.pgen.1005147  1
2015 Suez J, Korem T, Zilberman-Schapira G, Segal E, Elinav E. Non-caloric artificial sweeteners and the microbiome: findings and challenges. Gut Microbes. 6: 149-55. PMID 25831243 DOI: 10.1080/19490976.2015.1017700  1
2015 Levo M, Zalckvar E, Sharon E, Dantas Machado AC, Kalma Y, Lotam-Pompan M, Weinberger A, Yakhini Z, Rohs R, Segal E. Unraveling determinants of transcription factor binding outside the core binding site. Genome Research. PMID 25762553 DOI: 10.1101/gr.185033.114  1
2015 Manor O, Segal E. GenoExp: a web tool for predicting gene expression levels from single nucleotide polymorphisms. Bioinformatics (Oxford, England). 31: 1848-50. PMID 25637557 DOI: 10.1093/bioinformatics/btv050  1
2014 Weingarten-Gabbay S, Segal E. A shared architecture for promoters and enhancers. Nature Genetics. 46: 1253-4. PMID 25418744 DOI: 10.1038/ng.3152  1
2014 Thaiss CA, Zeevi D, Levy M, Zilberman-Schapira G, Suez J, Tengeler AC, Abramson L, Katz MN, Korem T, Zmora N, Kuperman Y, Biton I, Gilad S, Harmelin A, Shapiro H, ... ... Segal E, et al. Transkingdom control of microbiota diurnal oscillations promotes metabolic homeostasis. Cell. 159: 514-29. PMID 25417104 DOI: 10.1016/j.cell.2014.09.048  0.36
2014 Pilosof S, Fortuna MA, Cosson JF, Galan M, Kittipong C, Ribas A, Segal E, Krasnov BR, Morand S, Bascompte J. Host-parasite network structure is associated with community-level immunogenetic diversity. Nature Communications. 5: 5172. PMID 25312328 DOI: 10.1038/ncomms6172  1
2014 Zeevi D, Lubliner S, Lotan-Pompan M, Hodis E, Vesterman R, Weinberger A, Segal E. Molecular dissection of the genetic mechanisms that underlie expression conservation in orthologous yeast ribosomal promoters. Genome Research. 24: 1991-9. PMID 25294245 DOI: 10.1101/gr.179259.114  1
2014 Suez J, Korem T, Zeevi D, Zilberman-Schapira G, Thaiss CA, Maza O, Israeli D, Zmora N, Gilad S, Weinberger A, Kuperman Y, Harmelin A, Kolodkin-Gal I, Shapiro H, Halpern Z, ... Segal E, et al. Artificial sweeteners induce glucose intolerance by altering the gut microbiota. Nature. 514: 181-6. PMID 25231862 DOI: 10.1038/nature13793  0.48
2014 Sharon E, van Dijk D, Kalma Y, Keren L, Manor O, Yakhini Z, Segal E. Probing the effect of promoters on noise in gene expression using thousands of designed sequences. Genome Research. 24: 1698-706. PMID 25030889 DOI: 10.1101/gr.168773.113  1
2014 Levo M, Segal E. In pursuit of design principles of regulatory sequences. Nature Reviews. Genetics. 15: 453-68. PMID 24913666 DOI: 10.1038/nrg3684  1
2014 Wan Y, Qu K, Zhang QC, Flynn RA, Manor O, Ouyang Z, Zhang J, Spitale RC, Snyder MP, Segal E, Chang HY. Landscape and variation of RNA secondary structure across the human transcriptome. Nature. 505: 706-9. PMID 24476892 DOI: 10.1038/nature12946  1
2014 Weingarten-Gabbay S, Segal E. The grammar of transcriptional regulation. Human Genetics. 133: 701-11. PMID 24390306 DOI: 10.1007/s00439-013-1413-1  1
2013 Keren L, Segal E. Fixated on fixation: using ChIP to interrogate the dynamics of chromatin interactions. Genome Biology. 14: 138. PMID 24257511 DOI: 10.1186/gb4139  1
2013 Keren L, Zackay O, Lotan-Pompan M, Barenholz U, Dekel E, Sasson V, Aidelberg G, Bren A, Zeevi D, Weinberger A, Alon U, Milo R, Segal E. Promoters maintain their relative activity levels under different growth conditions. Molecular Systems Biology. 9: 701. PMID 24169404 DOI: 10.1038/msb.2013.59  1
2013 Manor O, Segal E. Predicting disease risk using bootstrap ranking and classification algorithms. Plos Computational Biology. 9: e1003200. PMID 23990773 DOI: 10.1371/journal.pcbi.1003200  1
2013 Meyer P, Siwo G, Zeevi D, Sharon E, Norel R, Segal E, Stolovitzky G. Inferring gene expression from ribosomal promoter sequences, a crowdsourcing approach. Genome Research. 23: 1928-37. PMID 23950146 DOI: 10.1101/gr.157420.113  1
2013 Zalckvar E, Paulus C, Tillo D, Asbach-Nitzsche A, Lubling Y, Winterling C, Strieder N, Mücke K, Goodrum F, Segal E, Nevels M. Nucleosome maps of the human cytomegalovirus genome reveal a temporal switch in chromatin organization linked to a major IE protein. Proceedings of the National Academy of Sciences of the United States of America. 110: 13126-31. PMID 23878222 DOI: 10.1073/pnas.1305548110  1
2013 Dvir S, Velten L, Sharon E, Zeevi D, Carey LB, Weinberger A, Segal E. Deciphering the rules by which 5'-UTR sequences affect protein expression in yeast. Proceedings of the National Academy of Sciences of the United States of America. 110: E2792-801. PMID 23832786 DOI: 10.1073/pnas.1222534110  1
2013 Lubliner S, Keren L, Segal E. Sequence features of yeast and human core promoters that are predictive of maximal promoter activity. Nucleic Acids Research. 41: 5569-81. PMID 23599004 DOI: 10.1093/nar/gkt256  1
2013 Carey LB, van Dijk D, Sloot PM, Kaandorp JA, Segal E. Promoter sequence determines the relationship between expression level and noise. Plos Biology. 11: e1001528. PMID 23565060 DOI: 10.1371/journal.pbio.1001528  1
2013 Manor O, Segal E. Robust prediction of expression differences among human individuals using only genotype information. Plos Genetics. 9: e1003396. PMID 23555302 DOI: 10.1371/journal.pgen.1003396  1
2013 Shalem O, Carey L, Zeevi D, Sharon E, Keren L, Weinberger A, Dahan O, Pilpel Y, Segal E. Measurements of the impact of 3' end sequences on gene expression reveal wide range and sequence dependent effects. Plos Computational Biology. 9: e1002934. PMID 23505350 DOI: 10.1371/journal.pcbi.1002934  1
2013 Struhl K, Segal E. Determinants of nucleosome positioning. Nature Structural & Molecular Biology. 20: 267-73. PMID 23463311 DOI: 10.1038/nsmb.2506  1
2013 Dadiani M, van Dijk D, Segal B, Field Y, Ben-Artzi G, Raveh-Sadka T, Levo M, Kaplow I, Weinberger A, Segal E. Two DNA-encoded strategies for increasing expression with opposing effects on promoter dynamics and transcriptional noise. Genome Research. 23: 966-76. PMID 23403035 DOI: 10.1101/gr.149096.112  1
2012 Wan Y, Qu K, Ouyang Z, Kertesz M, Li J, Tibshirani R, Makino DL, Nutter RC, Segal E, Chang HY. Genome-wide measurement of RNA folding energies. Molecular Cell. 48: 169-81. PMID 22981864 DOI: 10.1016/j.molcel.2012.08.008  1
2012 Ecker JR, Bickmore WA, Barroso I, Pritchard JK, Gilad Y, Segal E. Genomics: ENCODE explained. Nature. 489: 52-5. PMID 22955614 DOI: 10.1038/489052a  1
2012 Raveh-Sadka T, Levo M, Shabi U, Shany B, Keren L, Lotan-Pompan M, Zeevi D, Sharon E, Weinberger A, Segal E. Manipulating nucleosome disfavoring sequences allows fine-tune regulation of gene expression in yeast. Nature Genetics. 44: 743-50. PMID 22634752 DOI: 10.1038/ng.2305  1
2012 Sharon E, Kalma Y, Sharp A, Raveh-Sadka T, Levo M, Zeevi D, Keren L, Yakhini Z, Weinberger A, Segal E. Inferring gene regulatory logic from high-throughput measurements of thousands of systematically designed promoters. Nature Biotechnology. 30: 521-30. PMID 22609971 DOI: 10.1038/nbt.2205  1
2012 Reizel Y, Itzkovitz S, Adar R, Elbaz J, Jinich A, Chapal-Ilani N, Maruvka YE, Nevo N, Marx Z, Horovitz I, Wasserstrom A, Mayo A, Shur I, Benayahu D, Skorecki K, ... Segal E, et al. Cell lineage analysis of the mammalian female germline. Plos Genetics. 8: e1002477. PMID 22383887 DOI: 10.1371/journal.pgen.1002477  1
2012 Cayrou C, Coulombe P, Puy A, Rialle S, Kaplan N, Segal E, Méchali M. New insights into replication origin characteristics in metazoans. Cell Cycle (Georgetown, Tex.). 11: 658-67. PMID 22373526 DOI: 10.4161/cc.11.4.19097  1
2011 Zeevi D, Sharon E, Lotan-Pompan M, Lubling Y, Shipony Z, Raveh-Sadka T, Keren L, Levo M, Weinberger A, Segal E. Compensation for differences in gene copy number among yeast ribosomal proteins is encoded within their promoters. Genome Research. 21: 2114-28. PMID 22009988 DOI: 10.1101/gr.119669.110  1
2011 Wan Y, Kertesz M, Spitale RC, Segal E, Chang HY. Understanding the transcriptome through RNA structure. Nature Reviews. Genetics. 12: 641-55. PMID 21850044 DOI: 10.1038/nrg3049  1
2011 Field Y, Sharon E, Segal E. How transcription factors identify regulatory sites in genomic sequence. Sub-Cellular Biochemistry. 52: 193-204. PMID 21557084 DOI: 10.1007/978-90-481-9069-0_9  1
2011 Rabani M, Kertesz M, Segal E. Computational prediction of RNA structural motifs involved in post-transcriptional regulatory processes. Methods in Molecular Biology (Clifton, N.J.). 714: 467-79. PMID 21431758 DOI: 10.1007/978-1-61779-005-8_28  1
2011 Ercan S, Lubling Y, Segal E, Lieb JD. High nucleosome occupancy is encoded at X-linked gene promoters in C. elegans. Genome Research. 21: 237-44. PMID 21177966 DOI: 10.1101/gr.115931.110  1
2010 Kenigsberg E, Bar A, Segal E, Tanay A. Widespread compensatory evolution conserves DNA-encoded nucleosome organization in yeast. Plos Computational Biology. 6: e1001039. PMID 21203484 DOI: 10.1371/journal.pcbi.1001039  1
2010 Kaplan N, Hughes TR, Lieb JD, Widom J, Segal E. Contribution of histone sequence preferences to nucleosome organization: proposed definitions and methodology. Genome Biology. 11: 140. PMID 21118582 DOI: 10.1186/gb-2010-11-11-140  1
2010 Itzkovitz S, Hodis E, Segal E. Overlapping codes within protein-coding sequences. Genome Research. 20: 1582-9. PMID 20841429 DOI: 10.1101/gr.105072.110  1
2010 Kertesz M, Wan Y, Mazor E, Rinn JL, Nutter RC, Chang HY, Segal E. Genome-wide measurement of RNA secondary structure in yeast. Nature. 467: 103-7. PMID 20811459 DOI: 10.1038/nature09322  1
2010 Lidor Nili E, Field Y, Lubling Y, Widom J, Oren M, Segal E. p53 binds preferentially to genomic regions with high DNA-encoded nucleosome occupancy. Genome Research. 20: 1361-8. PMID 20716666 DOI: 10.1101/gr.103945.109  1
2010 Kaplan N, Moore I, Fondufe-Mittendorf Y, Gossett AJ, Tillo D, Field Y, Hughes TR, Lieb JD, Widom J, Segal E. Nucleosome sequence preferences influence in vivo nucleosome organization. Nature Structural & Molecular Biology. 17: 918-20; author reply. PMID 20683473 DOI: 10.1038/nsmb0810-918  1
2010 Tsai MC, Manor O, Wan Y, Mosammaparast N, Wang JK, Lan F, Shi Y, Segal E, Chang HY. Long noncoding RNA as modular scaffold of histone modification complexes. Science (New York, N.Y.). 329: 689-93. PMID 20616235 DOI: 10.1126/science.1192002  1
2010 Avraham R, Sas-Chen A, Manor O, Steinfeld I, Shalgi R, Tarcic G, Bossel N, Zeisel A, Amit I, Zwang Y, Enerly E, Russnes HG, Biagioni F, Mottolese M, Strano S, ... ... Segal E, et al. EGF decreases the abundance of microRNAs that restrain oncogenic transcription factors. Science Signaling. 3: ra43. PMID 20516477 DOI: 10.1126/scisignal.2000876  1
2010 Tillo D, Kaplan N, Moore IK, Fondufe-Mittendorf Y, Gossett AJ, Field Y, Lieb JD, Widom J, Segal E, Hughes TR. High nucleosome occupancy is encoded at human regulatory sequences. Plos One. 5: e9129. PMID 20161746 DOI: 10.1371/journal.pone.0009129  1
2009 Basu A, Rose KL, Zhang J, Beavis RC, Ueberheide B, Garcia BA, Chait B, Zhao Y, Hunt DF, Segal E, Allis CD, Hake SB. Proteome-wide prediction of acetylation substrates. Proceedings of the National Academy of Sciences of the United States of America. 106: 13785-90. PMID 19666589 DOI: 10.1073/pnas.0906801106  1
2009 Segal E, Widom J. What controls nucleosome positions? Trends in Genetics : Tig. 25: 335-43. PMID 19596482 DOI: 10.1016/j.tig.2009.06.002  1
2009 Segal E, Widom J. From DNA sequence to transcriptional behaviour: a quantitative approach. Nature Reviews. Genetics. 10: 443-56. PMID 19506578 DOI: 10.1038/nrg2591  1
2009 Lubliner S, Segal E. Modeling interactions between adjacent nucleosomes improves genome-wide predictions of nucleosome occupancy. Bioinformatics (Oxford, England). 25: i348-55. PMID 19478009 DOI: 10.1093/bioinformatics/btp216  1
2009 Raveh-Sadka T, Levo M, Segal E. Incorporating nucleosomes into thermodynamic models of transcription regulation. Genome Research. 19: 1480-96. PMID 19451592 DOI: 10.1101/gr.088260.108  1
2009 Field Y, Fondufe-Mittendorf Y, Moore IK, Mieczkowski P, Kaplan N, Lubling Y, Lieb JD, Widom J, Segal E. Gene expression divergence in yeast is coupled to evolution of DNA-encoded nucleosome organization. Nature Genetics. 41: 438-45. PMID 19252487 DOI: 10.1038/ng.324  1
2009 Segal E, Widom J. Poly(dA:dT) tracts: major determinants of nucleosome organization. Current Opinion in Structural Biology. 19: 65-71. PMID 19208466 DOI: 10.1016/j.sbi.2009.01.004  1
2009 Kaplan N, Moore IK, Fondufe-Mittendorf Y, Gossett AJ, Tillo D, Field Y, LeProust EM, Hughes TR, Lieb JD, Widom J, Segal E. The DNA-encoded nucleosome organization of a eukaryotic genome. Nature. 458: 362-6. PMID 19092803 DOI: 10.1038/nature07667  1
2008 Wong DJ, Segal E, Chang HY. Stemness, cancer and cancer stem cells. Cell Cycle (Georgetown, Tex.). 7: 3622-4. PMID 19029796  1
2008 Field Y, Kaplan N, Fondufe-Mittendorf Y, Moore IK, Sharon E, Lubling Y, Widom J, Segal E. Distinct modes of regulation by chromatin encoded through nucleosome positioning signals. Plos Computational Biology. 4: e1000216. PMID 18989395 DOI: 10.1371/journal.pcbi.1000216  1
2008 Shalem O, Dahan O, Levo M, Martinez MR, Furman I, Segal E, Pilpel Y. Transient transcriptional responses to stress are generated by opposing effects of mRNA production and degradation. Molecular Systems Biology. 4: 223. PMID 18854817 DOI: 10.1038/msb.2008.59  1
2008 Rabani M, Kertesz M, Segal E. Computational prediction of RNA structural motifs involved in posttranscriptional regulatory processes. Proceedings of the National Academy of Sciences of the United States of America. 105: 14885-90. PMID 18815376 DOI: 10.1073/pnas.0803169105  1
2008 Wang JP, Fondufe-Mittendorf Y, Xi L, Tsai GF, Segal E, Widom J. Preferentially quantized linker DNA lengths in Saccharomyces cerevisiae. Plos Computational Biology. 4: e1000175. PMID 18787693 DOI: 10.1371/journal.pcbi.1000175  1
2008 Sharon E, Lubliner S, Segal E. A feature-based approach to modeling protein-DNA interactions. Plos Computational Biology. 4: e1000154. PMID 18725950 DOI: 10.1371/journal.pcbi.1000154  1
2008 Baruch L, Itzkovitz S, Golan-Mashiach M, Shapiro E, Segal E. Using expression profiles of Caenorhabditis elegans neurons to identify genes that mediate synaptic connectivity. Plos Computational Biology. 4: e1000120. PMID 18711638 DOI: 10.1371/journal.pcbi.1000120  1
2008 Itzkovitz S, Baruch L, Shapiro E, Segal E. Geometric constraints on neuronal connectivity facilitate a concise synaptic adhesive code. Proceedings of the National Academy of Sciences of the United States of America. 105: 9278-83. PMID 18583478 DOI: 10.1073/pnas.0712207105  1
2008 Wasserstrom A, Frumkin D, Adar R, Itzkovitz S, Stern T, Kaplan S, Shefer G, Shur I, Zangi L, Reizel Y, Harmelin A, Dor Y, Dekel N, Reisner Y, Benayahu D, ... ... Segal E, et al. Estimating cell depth from somatic mutations. Plos Computational Biology. 4: e1000058. PMID 18404205 DOI: 10.1371/journal.pcbi.1000058  1
2008 Wasserstrom A, Adar R, Shefer G, Frumkin D, Itzkovitz S, Stern T, Shur I, Zangi L, Kaplan S, Harmelin A, Reisner Y, Benayahu D, Tzahor E, Segal E, Shapiro E. Reconstruction of cell lineage trees in mice. Plos One. 3: e1939. PMID 18398465 DOI: 10.1371/journal.pone.0001939  1
2008 Wong DJ, Liu H, Ridky TW, Cassarino D, Segal E, Chang HY. Module map of stem cell genes guides creation of epithelial cancer stem cells. Cell Stem Cell. 2: 333-44. PMID 18397753 DOI: 10.1016/j.stem.2008.02.009  1
2008 Minsky N, Shema E, Field Y, Schuster M, Segal E, Oren M. Monoubiquitinated H2B is associated with the transcribed region of highly expressed genes in human cells. Nature Cell Biology. 10: 483-8. PMID 18344985 DOI: 10.1038/ncb1712  1
2008 Adler AS, Kawahara TL, Segal E, Chang HY. Reversal of aging by NFkappaB blockade. Cell Cycle (Georgetown, Tex.). 7: 556-9. PMID 18256548  1
2008 Sinha S, Adler AS, Field Y, Chang HY, Segal E. Systematic functional characterization of cis-regulatory motifs in human core promoters. Genome Research. 18: 477-88. PMID 18256240 DOI: 10.1101/gr.6828808  1
2008 Wong DJ, Nuyten DS, Regev A, Lin M, Adler AS, Segal E, van de Vijver MJ, Chang HY. Revealing targeted therapy for human cancer by gene module maps. Cancer Research. 68: 369-78. PMID 18199530 DOI: 10.1158/0008-5472.CAN-07-0382  1
2008 Segal E, Raveh-Sadka T, Schroeder M, Unnerstall U, Gaul U. Predicting expression patterns from regulatory sequence in Drosophila segmentation. Nature. 451: 535-40. PMID 18172436 DOI: 10.1038/nature06496  1
2007 Adler AS, Sinha S, Kawahara TL, Zhang JY, Segal E, Chang HY. Motif module map reveals enforcement of aging by continual NF-kappaB activity. Genes & Development. 21: 3244-57. PMID 18055696 DOI: 10.1101/gad.1588507  1
2007 Kertesz M, Iovino N, Unnerstall U, Gaul U, Segal E. The role of site accessibility in microRNA target recognition. Nature Genetics. 39: 1278-84. PMID 17893677 DOI: 10.1038/ng2135  1
2007 Wang H, Segal E, Ben-Hur A, Li QR, Vidal M, Koller D. InSite: a computational method for identifying protein-protein interaction binding sites on a proteome-wide scale. Genome Biology. 8: R192. PMID 17868464 DOI: 10.1186/gb-2007-8-9-r192  1
2007 Rinn JL, Kertesz M, Wang JK, Squazzo SL, Xu X, Brugmann SA, Goodnough LH, Helms JA, Farnham PJ, Segal E, Chang HY. Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell. 129: 1311-23. PMID 17604720 DOI: 10.1016/j.cell.2007.05.022  1
2007 Liu H, Adler AS, Segal E, Chang HY. A transcriptional program mediating entry into cellular quiescence. Plos Genetics. 3: e91. PMID 17559306 DOI: 10.1371/journal.pgen.0030091  1
2007 Segal E, Sirlin CB, Ooi C, Adler AS, Gollub J, Chen X, Chan BK, Matcuk GR, Barry CT, Chang HY, Kuo MD. Decoding global gene expression programs in liver cancer by noninvasive imaging. Nature Biotechnology. 25: 675-80. PMID 17515910 DOI: 10.1038/nbt1306  1
2007 Achiron A, Gurevich M, Snir Y, Segal E, Mandel M. Zinc-ion binding and cytokine activity regulation pathways predicts outcome in relapsing-remitting multiple sclerosis. Clinical and Experimental Immunology. 149: 235-42. PMID 17488294 DOI: 10.1111/j.1365-2249.2007.03405.x  1
2007 Amit I, Citri A, Shay T, Lu Y, Katz M, Zhang F, Tarcic G, Siwak D, Lahad J, Jacob-Hirsch J, Amariglio N, Vaisman N, Segal E, Rechavi G, Alon U, et al. A module of negative feedback regulators defines growth factor signaling. Nature Genetics. 39: 503-12. PMID 17322878 DOI: 10.1038/ng1987  1
2006 Segal E, Fondufe-Mittendorf Y, Chen L, Thåström A, Field Y, Moore IK, Wang JP, Widom J. A genomic code for nucleosome positioning. Nature. 442: 772-8. PMID 16862119 DOI: 10.1038/nature04979  1
2006 Keshet I, Schlesinger Y, Farkash S, Rand E, Hecht M, Segal E, Pikarski E, Young RA, Niveleau A, Cedar H, Simon I. Evidence for an instructive mechanism of de novo methylation in cancer cells. Nature Genetics. 38: 149-53. PMID 16444255 DOI: 10.1038/ng1719  1
2006 Matias Y, Segal E, Vitter JS. Efficient bundle sorting Siam Journal On Computing. 36: 394-410. DOI: 10.1137/S0097539704446554  1
2005 Battle A, Segal E, Koller D. Probabilistic discovery of overlapping cellular processes and their regulation. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 12: 909-27. PMID 16201912 DOI: 10.1089/cmb.2005.12.909  1
2005 Segal E, Sharan R. A discriminative model for identifying spatial cis-regulatory modules Journal of Computational Biology. 12: 822-834. PMID 16108719 DOI: 10.1089/cmb.2005.12.822  1
2005 Segal E, Friedman N, Kaminski N, Regev A, Koller D. From signatures to models: understanding cancer using microarrays. Nature Genetics. 37: S38-45. PMID 15920529 DOI: 10.1038/ng1561  1
2005 Hartemink AJ, Segal E. Joint learning from multiple types of genomic data. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 445-6. PMID 15759649  1
2005 Segal E, Pe'er D, Regev A, Koller D, Friedman N. Learning module networks Journal of Machine Learning Research. 6.  1
2005 Wang H, Segal E, Ben-Hur A, Koller D, Brutlag DL. Identifying protein-protein interaction sites on a genome-wide scale Advances in Neural Information Processing Systems 1
2004 Segal E, Friedman N, Koller D, Regev A. A module map showing conditional activity of expression modules in cancer. Nature Genetics. 36: 1090-8. PMID 15448693 DOI: 10.1038/ng1434  0.96
2004 Marion RM, Regev A, Segal E, Barash Y, Koller D, Friedman N, O'Shea EK. Sfp1 is a stress- and nutrient-sensitive regulator of ribosomal protein gene expression. Proceedings of the National Academy of Sciences of the United States of America. 101: 14315-22. PMID 15353587 DOI: 10.1073/pnas.0405353101  1
2003 Stuart JM, Segal E, Koller D, Kim SK. A gene-coexpression network for global discovery of conserved genetic modules. Science (New York, N.Y.). 302: 249-55. PMID 12934013 DOI: 10.1126/science.1087447  1
2003 Segal E, Yelensky R, Koller D. Genome-wide discovery of transcriptional modules from DNA sequence and gene expression. Bioinformatics (Oxford, England). 19: i273-82. PMID 12855470  1
2003 Segal E, Wang H, Koller D. Discovering molecular pathways from protein interaction and gene expression data. Bioinformatics (Oxford, England). 19: i264-71. PMID 12855469 DOI: 10.1093/bioinformatics/btg1037  1
2003 Segal E, Shapira M, Regev A, Pe'er D, Botstein D, Koller D, Friedman N. Module networks: identifying regulatory modules and their condition-specific regulators from gene expression data. Nature Genetics. 34: 166-76. PMID 12740579 DOI: 10.1038/ng1165  1
2003 Segal E, Battle A, Koller D. Decomposing gene expression into cellular processes. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 89-100. PMID 12603020  1
2001 Segal E, Taskar B, Gasch A, Friedman N, Koller D. Rich probabilistic models for gene expression. Bioinformatics (Oxford, England). 17: S243-52. PMID 11473015  1
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