| Year |
Citation |
Score |
| 2020 |
Nejman D, Livyatan I, Fuks G, Gavert N, Zwang Y, Geller LT, Rotter-Maskowitz A, Weiser R, Mallel G, Gigi E, Meltser A, Douglas GM, Kamer I, Gopalakrishnan V, Dadosh T, ... ... Segal E, et al. The human tumor microbiome is composed of tumor type-specific intracellular bacteria. Science (New York, N.Y.). 368: 973-980. PMID 32467386 DOI: 10.1126/science.aay9189 |
0.44 |
|
| 2019 |
Slutskin IV, Weinberger A, Segal E. Sequence determinants of polyadenylation-mediated regulation. Genome Research. PMID 31530582 DOI: 10.1101/gr.247312.118 |
0.44 |
|
| 2019 |
Zeevi D, Korem T, Godneva A, Bar N, Kurilshikov A, Lotan-Pompan M, Weinberger A, Fu J, Wijmenga C, Zhernakova A, Segal E. Structural variation in the gut microbiome associates with host health. Nature. PMID 30918406 DOI: 10.1038/s41586-019-1065-y |
0.44 |
|
| 2019 |
Weingarten-Gabbay S, Nir R, Lubliner S, Sharon E, Kalma Y, Weinberger A, Segal E. Systematic interrogation of human promoters. Genome Research. PMID 30622120 DOI: 10.1101/gr.236075.118 |
0.44 |
|
| 2018 |
Rothschild D, Weissbrod O, Barkan E, Kurilshikov A, Korem T, Zeevi D, Costea PI, Godneva A, Kalka IN, Bar N, Shilo S, Lador D, Vila AV, Zmora N, Pevsner-Fischer M, ... ... Segal E, et al. Environment dominates over host genetics in shaping human gut microbiota. Nature. PMID 29489753 DOI: 10.1038/nature25973 |
0.44 |
|
| 2018 |
Vainberg Slutskin I, Weingarten-Gabbay S, Nir R, Weinberger A, Segal E. Unraveling the determinants of microRNA mediated regulation using a massively parallel reporter assay. Nature Communications. 9: 529. PMID 29410437 DOI: 10.1038/s41467-018-02980-z |
0.44 |
|
| 2017 |
Korem T, Zeevi D, Zmora N, Weissbrod O, Bar N, Lotan-Pompan M, Avnit-Sagi T, Kosower N, Malka G, Rein M, Suez J, Goldberg BZ, Weinberger A, Levy AA, Elinav E, ... Segal E, et al. Bread Affects Clinical Parameters and Induces Gut Microbiome-Associated Personal Glycemic Responses. Cell Metabolism. 25: 1243-1253.e5. PMID 28591632 DOI: 10.1016/j.cmet.2017.05.002 |
0.44 |
|
| 2017 |
Rowan S, Jiang S, Korem T, Szymanski J, Chang ML, Szelog J, Cassalman C, Dasuri K, McGuire C, Nagai R, Du XL, Brownlee M, Rabbani N, Thornalley PJ, Baleja JD, ... ... Segal E, et al. Involvement of a gut-retina axis in protection against dietary glycemia-induced age-related macular degeneration. Proceedings of the National Academy of Sciences of the United States of America. PMID 28507131 DOI: 10.1073/pnas.1702302114 |
0.44 |
|
| 2017 |
van Dijk D, Sharon E, Lotan-Pompan M, Weinberger A, Segal E, Carey LB. Corrigendum: Large-scale mapping of gene regulatory logic reveals context-dependent repression by transcriptional activators. Genome Research. 27: 500. PMID 28250019 DOI: 10.1101/gr.220574.117 |
0.44 |
|
| 2017 |
Levo M, Avnit-Sagi T, Lotan-Pompan M, Kalma Y, Weinberger A, Yakhini Z, Segal E. Systematic Investigation of Transcription Factor Activity in the Context of Chromatin Using Massively Parallel Binding and Expression Assays. Molecular Cell. 65: 604-617.e6. PMID 28212748 DOI: 10.1016/j.molcel.2017.01.007 |
1 |
|
| 2016 |
van Dijk D, Sharon E, Lotan-Pompan M, Weinberger A, Segal E, Carey L. Large scale mapping of gene regulatory logic reveals context dependent repression by transcriptional activators. Genome Research. PMID 27965290 DOI: 10.1101/gr.212316.116 |
0.44 |
|
| 2016 |
Keren L, Hausser J, Lotan-Pompan M, Vainberg Slutskin I, Alisar H, Kaminski S, Weinberger A, Alon U, Milo R, Segal E. Massively Parallel Interrogation of the Effects of Gene Expression Levels on Fitness. Cell. PMID 27545349 DOI: 10.1016/j.cell.2016.07.024 |
1 |
|
| 2016 |
Barenholz U, Keren L, Segal E, Milo R. A Minimalistic Resource Allocation Model to Explain Ubiquitous Increase in Protein Expression with Growth Rate. Plos One. 11: e0153344. PMID 27073913 DOI: 10.1371/journal.pone.0153344 |
1 |
|
| 2016 |
Zeevi D, Korem T, Segal E. Talking about cross-talk: the immune system and the microbiome. Genome Biology. 17: 50. PMID 26987366 DOI: 10.1186/s13059-016-0921-4 |
1 |
|
| 2016 |
Weingarten-Gabbay S, Elias-Kirma S, Nir R, Gritsenko AA, Stern-Ginossar N, Yakhini Z, Weinberger A, Segal E. Comparative genetics. Systematic discovery of cap-independent translation sequences in human and viral genomes. Science (New York, N.Y.). 351. PMID 26816383 DOI: 10.1126/science.aad4939 |
1 |
|
| 2016 |
Qu K, Garamszegi S, Wu F, Thorvaldsdottir H, Liefeld T, Ocana M, Borges-Rivera D, Pochet N, Robinson JT, Demchak B, Hull T, Ben-Artzi G, Blankenberg D, Barber GP, Lee BT, ... ... Segal E, et al. Integrative genomic analysis by interoperation of bioinformatics tools in GenomeSpace. Nature Methods. PMID 26780094 DOI: 10.1038/nmeth.3732 |
0.44 |
|
| 2016 |
Zmora N, Zeevi D, Korem T, Segal E, Elinav E. Taking it Personally: Personalized Utilization of the Human Microbiome in Health and Disease. Cell Host & Microbe. 19: 12-20. PMID 26764593 DOI: 10.1016/j.chom.2015.12.016 |
1 |
|
| 2015 |
Levy M, Thaiss CA, Zeevi D, Dohnalová L, Zilberman-Schapira G, Mahdi JA, David E, Savidor A, Korem T, Herzig Y, Pevsner-Fischer M, Shapiro H, Christ A, Harmelin A, Halpern Z, ... ... Segal E, et al. Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling. Cell. 163: 1428-43. PMID 26638072 DOI: 10.1016/j.cell.2015.10.048 |
1 |
|
| 2015 |
Zeevi D, Korem T, Zmora N, Israeli D, Rothschild D, Weinberger A, Ben-Yacov O, Lador D, Avnit-Sagi T, Lotan-Pompan M, Suez J, Mahdi JA, Matot E, Malka G, Kosower N, ... ... Segal E, et al. Personalized Nutrition by Prediction of Glycemic Responses. Cell. 163: 1079-94. PMID 26590418 DOI: 10.1016/j.cell.2015.11.001 |
1 |
|
| 2015 |
Keren L, van Dijk D, Weingarten-Gabbay S, Davidi D, Jona G, Weinberger A, Milo R, Segal E. Noise in gene expression is coupled to growth rate. Genome Research. 25: 1893-902. PMID 26355006 DOI: 10.1101/gr.191635.115 |
1 |
|
| 2015 |
Levo M, Zalckvar E, Sharon E, Dantas Machado AC, Kalma Y, Lotan-Pompan M, Weinberger A, Yakhini Z, Rohs R, Segal E. Corrigendum: Unraveling determinants of transcription factor binding outside the core binding site. Genome Research. 25: 1410.2. PMID 26330574 DOI: 25/9/1410.2 |
1 |
|
| 2015 |
Korem T, Zeevi D, Suez J, Weinberger A, Avnit-Sagi T, Pompan-Lotan M, Matot E, Jona G, Harmelin A, Cohen N, Sirota-Madi A, Thaiss CA, Pevsner-Fischer M, Sorek R, Xavier R, ... ... Segal E, et al. Growth dynamics of gut microbiota in health and disease inferred from single metagenomic samples. Science (New York, N.Y.). PMID 26229116 DOI: 10.1126/science.aac4812 |
1 |
|
| 2015 |
Panning B, Segal E. Editorial overview: Genome architecture and expression. Current Opinion in Genetics & Development. 31: v-vi. PMID 26051228 DOI: 10.1016/j.gde.2015.05.003 |
1 |
|
| 2015 |
Lubliner S, Regev I, Lotan-Pompan M, Edelheit S, Weinberger A, Segal E. Core promoter sequence in yeast is a major determinant of expression level. Genome Research. 25: 1008-17. PMID 25969468 DOI: 10.1101/gr.188193.114 |
1 |
|
| 2015 |
Shalem O, Sharon E, Lubliner S, Regev I, Lotan-Pompan M, Yakhini Z, Segal E. Systematic dissection of the sequence determinants of gene 3' end mediated expression control. Plos Genetics. 11: e1005147. PMID 25875337 DOI: 10.1371/journal.pgen.1005147 |
1 |
|
| 2015 |
Suez J, Korem T, Zilberman-Schapira G, Segal E, Elinav E. Non-caloric artificial sweeteners and the microbiome: findings and challenges. Gut Microbes. 6: 149-55. PMID 25831243 DOI: 10.1080/19490976.2015.1017700 |
1 |
|
| 2015 |
Levo M, Zalckvar E, Sharon E, Dantas Machado AC, Kalma Y, Lotam-Pompan M, Weinberger A, Yakhini Z, Rohs R, Segal E. Unraveling determinants of transcription factor binding outside the core binding site. Genome Research. PMID 25762553 DOI: 10.1101/gr.185033.114 |
1 |
|
| 2015 |
Manor O, Segal E. GenoExp: a web tool for predicting gene expression levels from single nucleotide polymorphisms. Bioinformatics (Oxford, England). 31: 1848-50. PMID 25637557 DOI: 10.1093/bioinformatics/btv050 |
1 |
|
| 2014 |
Weingarten-Gabbay S, Segal E. A shared architecture for promoters and enhancers. Nature Genetics. 46: 1253-4. PMID 25418744 DOI: 10.1038/ng.3152 |
1 |
|
| 2014 |
Pilosof S, Fortuna MA, Cosson JF, Galan M, Kittipong C, Ribas A, Segal E, Krasnov BR, Morand S, Bascompte J. Host-parasite network structure is associated with community-level immunogenetic diversity. Nature Communications. 5: 5172. PMID 25312328 DOI: 10.1038/ncomms6172 |
1 |
|
| 2014 |
Zeevi D, Lubliner S, Lotan-Pompan M, Hodis E, Vesterman R, Weinberger A, Segal E. Molecular dissection of the genetic mechanisms that underlie expression conservation in orthologous yeast ribosomal promoters. Genome Research. 24: 1991-9. PMID 25294245 DOI: 10.1101/gr.179259.114 |
1 |
|
| 2014 |
Suez J, Korem T, Zeevi D, Zilberman-Schapira G, Thaiss CA, Maza O, Israeli D, Zmora N, Gilad S, Weinberger A, Kuperman Y, Harmelin A, Kolodkin-Gal I, Shapiro H, Halpern Z, ... Segal E, et al. Artificial sweeteners induce glucose intolerance by altering the gut microbiota. Nature. 514: 181-6. PMID 25231862 DOI: 10.1038/nature13793 |
0.44 |
|
| 2014 |
Sharon E, van Dijk D, Kalma Y, Keren L, Manor O, Yakhini Z, Segal E. Probing the effect of promoters on noise in gene expression using thousands of designed sequences. Genome Research. 24: 1698-706. PMID 25030889 DOI: 10.1101/gr.168773.113 |
1 |
|
| 2014 |
Levo M, Segal E. In pursuit of design principles of regulatory sequences. Nature Reviews. Genetics. 15: 453-68. PMID 24913666 DOI: 10.1038/nrg3684 |
1 |
|
| 2014 |
Wan Y, Qu K, Zhang QC, Flynn RA, Manor O, Ouyang Z, Zhang J, Spitale RC, Snyder MP, Segal E, Chang HY. Landscape and variation of RNA secondary structure across the human transcriptome. Nature. 505: 706-9. PMID 24476892 DOI: 10.1038/nature12946 |
1 |
|
| 2014 |
Weingarten-Gabbay S, Segal E. The grammar of transcriptional regulation. Human Genetics. 133: 701-11. PMID 24390306 DOI: 10.1007/s00439-013-1413-1 |
1 |
|
| 2013 |
Keren L, Segal E. Fixated on fixation: using ChIP to interrogate the dynamics of chromatin interactions. Genome Biology. 14: 138. PMID 24257511 DOI: 10.1186/gb4139 |
1 |
|
| 2013 |
Keren L, Zackay O, Lotan-Pompan M, Barenholz U, Dekel E, Sasson V, Aidelberg G, Bren A, Zeevi D, Weinberger A, Alon U, Milo R, Segal E. Promoters maintain their relative activity levels under different growth conditions. Molecular Systems Biology. 9: 701. PMID 24169404 DOI: 10.1038/msb.2013.59 |
1 |
|
| 2013 |
Manor O, Segal E. Predicting disease risk using bootstrap ranking and classification algorithms. Plos Computational Biology. 9: e1003200. PMID 23990773 DOI: 10.1371/journal.pcbi.1003200 |
1 |
|
| 2013 |
Meyer P, Siwo G, Zeevi D, Sharon E, Norel R, Segal E, Stolovitzky G. Inferring gene expression from ribosomal promoter sequences, a crowdsourcing approach. Genome Research. 23: 1928-37. PMID 23950146 DOI: 10.1101/gr.157420.113 |
1 |
|
| 2013 |
Zalckvar E, Paulus C, Tillo D, Asbach-Nitzsche A, Lubling Y, Winterling C, Strieder N, Mücke K, Goodrum F, Segal E, Nevels M. Nucleosome maps of the human cytomegalovirus genome reveal a temporal switch in chromatin organization linked to a major IE protein. Proceedings of the National Academy of Sciences of the United States of America. 110: 13126-31. PMID 23878222 DOI: 10.1073/pnas.1305548110 |
1 |
|
| 2013 |
Dvir S, Velten L, Sharon E, Zeevi D, Carey LB, Weinberger A, Segal E. Deciphering the rules by which 5'-UTR sequences affect protein expression in yeast. Proceedings of the National Academy of Sciences of the United States of America. 110: E2792-801. PMID 23832786 DOI: 10.1073/pnas.1222534110 |
1 |
|
| 2013 |
Lubliner S, Keren L, Segal E. Sequence features of yeast and human core promoters that are predictive of maximal promoter activity. Nucleic Acids Research. 41: 5569-81. PMID 23599004 DOI: 10.1093/nar/gkt256 |
1 |
|
| 2013 |
Carey LB, van Dijk D, Sloot PM, Kaandorp JA, Segal E. Promoter sequence determines the relationship between expression level and noise. Plos Biology. 11: e1001528. PMID 23565060 DOI: 10.1371/journal.pbio.1001528 |
1 |
|
| 2013 |
Manor O, Segal E. Robust prediction of expression differences among human individuals using only genotype information. Plos Genetics. 9: e1003396. PMID 23555302 DOI: 10.1371/journal.pgen.1003396 |
1 |
|
| 2013 |
Shalem O, Carey L, Zeevi D, Sharon E, Keren L, Weinberger A, Dahan O, Pilpel Y, Segal E. Measurements of the impact of 3' end sequences on gene expression reveal wide range and sequence dependent effects. Plos Computational Biology. 9: e1002934. PMID 23505350 DOI: 10.1371/journal.pcbi.1002934 |
1 |
|
| 2013 |
Struhl K, Segal E. Determinants of nucleosome positioning. Nature Structural & Molecular Biology. 20: 267-73. PMID 23463311 DOI: 10.1038/nsmb.2506 |
1 |
|
| 2013 |
Dadiani M, van Dijk D, Segal B, Field Y, Ben-Artzi G, Raveh-Sadka T, Levo M, Kaplow I, Weinberger A, Segal E. Two DNA-encoded strategies for increasing expression with opposing effects on promoter dynamics and transcriptional noise. Genome Research. 23: 966-76. PMID 23403035 DOI: 10.1101/gr.149096.112 |
1 |
|
| 2012 |
Wan Y, Qu K, Ouyang Z, Kertesz M, Li J, Tibshirani R, Makino DL, Nutter RC, Segal E, Chang HY. Genome-wide measurement of RNA folding energies. Molecular Cell. 48: 169-81. PMID 22981864 DOI: 10.1016/j.molcel.2012.08.008 |
1 |
|
| 2012 |
Ecker JR, Bickmore WA, Barroso I, Pritchard JK, Gilad Y, Segal E. Genomics: ENCODE explained. Nature. 489: 52-5. PMID 22955614 DOI: 10.1038/489052a |
1 |
|
| 2012 |
Raveh-Sadka T, Levo M, Shabi U, Shany B, Keren L, Lotan-Pompan M, Zeevi D, Sharon E, Weinberger A, Segal E. Manipulating nucleosome disfavoring sequences allows fine-tune regulation of gene expression in yeast. Nature Genetics. 44: 743-50. PMID 22634752 DOI: 10.1038/ng.2305 |
1 |
|
| 2012 |
Sharon E, Kalma Y, Sharp A, Raveh-Sadka T, Levo M, Zeevi D, Keren L, Yakhini Z, Weinberger A, Segal E. Inferring gene regulatory logic from high-throughput measurements of thousands of systematically designed promoters. Nature Biotechnology. 30: 521-30. PMID 22609971 DOI: 10.1038/nbt.2205 |
1 |
|
| 2012 |
Reizel Y, Itzkovitz S, Adar R, Elbaz J, Jinich A, Chapal-Ilani N, Maruvka YE, Nevo N, Marx Z, Horovitz I, Wasserstrom A, Mayo A, Shur I, Benayahu D, Skorecki K, ... Segal E, et al. Cell lineage analysis of the mammalian female germline. Plos Genetics. 8: e1002477. PMID 22383887 DOI: 10.1371/journal.pgen.1002477 |
1 |
|
| 2012 |
Cayrou C, Coulombe P, Puy A, Rialle S, Kaplan N, Segal E, Méchali M. New insights into replication origin characteristics in metazoans. Cell Cycle (Georgetown, Tex.). 11: 658-67. PMID 22373526 DOI: 10.4161/cc.11.4.19097 |
1 |
|
| 2011 |
Zeevi D, Sharon E, Lotan-Pompan M, Lubling Y, Shipony Z, Raveh-Sadka T, Keren L, Levo M, Weinberger A, Segal E. Compensation for differences in gene copy number among yeast ribosomal proteins is encoded within their promoters. Genome Research. 21: 2114-28. PMID 22009988 DOI: 10.1101/gr.119669.110 |
1 |
|
| 2011 |
Wan Y, Kertesz M, Spitale RC, Segal E, Chang HY. Understanding the transcriptome through RNA structure. Nature Reviews. Genetics. 12: 641-55. PMID 21850044 DOI: 10.1038/nrg3049 |
1 |
|
| 2011 |
Field Y, Sharon E, Segal E. How transcription factors identify regulatory sites in genomic sequence. Sub-Cellular Biochemistry. 52: 193-204. PMID 21557084 DOI: 10.1007/978-90-481-9069-0_9 |
1 |
|
| 2011 |
Rabani M, Kertesz M, Segal E. Computational prediction of RNA structural motifs involved in post-transcriptional regulatory processes. Methods in Molecular Biology (Clifton, N.J.). 714: 467-79. PMID 21431758 DOI: 10.1007/978-1-61779-005-8_28 |
1 |
|
| 2011 |
Ercan S, Lubling Y, Segal E, Lieb JD. High nucleosome occupancy is encoded at X-linked gene promoters in C. elegans. Genome Research. 21: 237-44. PMID 21177966 DOI: 10.1101/gr.115931.110 |
1 |
|
| 2010 |
Kenigsberg E, Bar A, Segal E, Tanay A. Widespread compensatory evolution conserves DNA-encoded nucleosome organization in yeast. Plos Computational Biology. 6: e1001039. PMID 21203484 DOI: 10.1371/journal.pcbi.1001039 |
1 |
|
| 2010 |
Kaplan N, Hughes TR, Lieb JD, Widom J, Segal E. Contribution of histone sequence preferences to nucleosome organization: proposed definitions and methodology. Genome Biology. 11: 140. PMID 21118582 DOI: 10.1186/gb-2010-11-11-140 |
1 |
|
| 2010 |
Itzkovitz S, Hodis E, Segal E. Overlapping codes within protein-coding sequences. Genome Research. 20: 1582-9. PMID 20841429 DOI: 10.1101/gr.105072.110 |
1 |
|
| 2010 |
Kertesz M, Wan Y, Mazor E, Rinn JL, Nutter RC, Chang HY, Segal E. Genome-wide measurement of RNA secondary structure in yeast. Nature. 467: 103-7. PMID 20811459 DOI: 10.1038/nature09322 |
1 |
|
| 2010 |
Lidor Nili E, Field Y, Lubling Y, Widom J, Oren M, Segal E. p53 binds preferentially to genomic regions with high DNA-encoded nucleosome occupancy. Genome Research. 20: 1361-8. PMID 20716666 DOI: 10.1101/gr.103945.109 |
1 |
|
| 2010 |
Kaplan N, Moore I, Fondufe-Mittendorf Y, Gossett AJ, Tillo D, Field Y, Hughes TR, Lieb JD, Widom J, Segal E. Nucleosome sequence preferences influence in vivo nucleosome organization. Nature Structural & Molecular Biology. 17: 918-20; author reply. PMID 20683473 DOI: 10.1038/nsmb0810-918 |
1 |
|
| 2010 |
Tsai MC, Manor O, Wan Y, Mosammaparast N, Wang JK, Lan F, Shi Y, Segal E, Chang HY. Long noncoding RNA as modular scaffold of histone modification complexes. Science (New York, N.Y.). 329: 689-93. PMID 20616235 DOI: 10.1126/science.1192002 |
1 |
|
| 2010 |
Avraham R, Sas-Chen A, Manor O, Steinfeld I, Shalgi R, Tarcic G, Bossel N, Zeisel A, Amit I, Zwang Y, Enerly E, Russnes HG, Biagioni F, Mottolese M, Strano S, ... ... Segal E, et al. EGF decreases the abundance of microRNAs that restrain oncogenic transcription factors. Science Signaling. 3: ra43. PMID 20516477 DOI: 10.1126/scisignal.2000876 |
1 |
|
| 2010 |
Tillo D, Kaplan N, Moore IK, Fondufe-Mittendorf Y, Gossett AJ, Field Y, Lieb JD, Widom J, Segal E, Hughes TR. High nucleosome occupancy is encoded at human regulatory sequences. Plos One. 5: e9129. PMID 20161746 DOI: 10.1371/journal.pone.0009129 |
1 |
|
| 2009 |
Basu A, Rose KL, Zhang J, Beavis RC, Ueberheide B, Garcia BA, Chait B, Zhao Y, Hunt DF, Segal E, Allis CD, Hake SB. Proteome-wide prediction of acetylation substrates. Proceedings of the National Academy of Sciences of the United States of America. 106: 13785-90. PMID 19666589 DOI: 10.1073/pnas.0906801106 |
1 |
|
| 2009 |
Segal E, Widom J. What controls nucleosome positions? Trends in Genetics : Tig. 25: 335-43. PMID 19596482 DOI: 10.1016/j.tig.2009.06.002 |
1 |
|
| 2009 |
Segal E, Widom J. From DNA sequence to transcriptional behaviour: a quantitative approach. Nature Reviews. Genetics. 10: 443-56. PMID 19506578 DOI: 10.1038/nrg2591 |
1 |
|
| 2009 |
Lubliner S, Segal E. Modeling interactions between adjacent nucleosomes improves genome-wide predictions of nucleosome occupancy. Bioinformatics (Oxford, England). 25: i348-55. PMID 19478009 DOI: 10.1093/bioinformatics/btp216 |
1 |
|
| 2009 |
Raveh-Sadka T, Levo M, Segal E. Incorporating nucleosomes into thermodynamic models of transcription regulation. Genome Research. 19: 1480-96. PMID 19451592 DOI: 10.1101/gr.088260.108 |
1 |
|
| 2009 |
Field Y, Fondufe-Mittendorf Y, Moore IK, Mieczkowski P, Kaplan N, Lubling Y, Lieb JD, Widom J, Segal E. Gene expression divergence in yeast is coupled to evolution of DNA-encoded nucleosome organization. Nature Genetics. 41: 438-45. PMID 19252487 DOI: 10.1038/ng.324 |
1 |
|
| 2009 |
Segal E, Widom J. Poly(dA:dT) tracts: major determinants of nucleosome organization. Current Opinion in Structural Biology. 19: 65-71. PMID 19208466 DOI: 10.1016/j.sbi.2009.01.004 |
1 |
|
| 2009 |
Kaplan N, Moore IK, Fondufe-Mittendorf Y, Gossett AJ, Tillo D, Field Y, LeProust EM, Hughes TR, Lieb JD, Widom J, Segal E. The DNA-encoded nucleosome organization of a eukaryotic genome. Nature. 458: 362-6. PMID 19092803 DOI: 10.1038/nature07667 |
1 |
|
| 2008 |
Wong DJ, Segal E, Chang HY. Stemness, cancer and cancer stem cells. Cell Cycle (Georgetown, Tex.). 7: 3622-4. PMID 19029796 |
1 |
|
| 2008 |
Field Y, Kaplan N, Fondufe-Mittendorf Y, Moore IK, Sharon E, Lubling Y, Widom J, Segal E. Distinct modes of regulation by chromatin encoded through nucleosome positioning signals. Plos Computational Biology. 4: e1000216. PMID 18989395 DOI: 10.1371/journal.pcbi.1000216 |
1 |
|
| 2008 |
Shalem O, Dahan O, Levo M, Martinez MR, Furman I, Segal E, Pilpel Y. Transient transcriptional responses to stress are generated by opposing effects of mRNA production and degradation. Molecular Systems Biology. 4: 223. PMID 18854817 DOI: 10.1038/msb.2008.59 |
1 |
|
| 2008 |
Rabani M, Kertesz M, Segal E. Computational prediction of RNA structural motifs involved in posttranscriptional regulatory processes. Proceedings of the National Academy of Sciences of the United States of America. 105: 14885-90. PMID 18815376 DOI: 10.1073/pnas.0803169105 |
1 |
|
| 2008 |
Wang JP, Fondufe-Mittendorf Y, Xi L, Tsai GF, Segal E, Widom J. Preferentially quantized linker DNA lengths in Saccharomyces cerevisiae. Plos Computational Biology. 4: e1000175. PMID 18787693 DOI: 10.1371/journal.pcbi.1000175 |
1 |
|
| 2008 |
Sharon E, Lubliner S, Segal E. A feature-based approach to modeling protein-DNA interactions. Plos Computational Biology. 4: e1000154. PMID 18725950 DOI: 10.1371/journal.pcbi.1000154 |
1 |
|
| 2008 |
Baruch L, Itzkovitz S, Golan-Mashiach M, Shapiro E, Segal E. Using expression profiles of Caenorhabditis elegans neurons to identify genes that mediate synaptic connectivity. Plos Computational Biology. 4: e1000120. PMID 18711638 DOI: 10.1371/journal.pcbi.1000120 |
1 |
|
| 2008 |
Itzkovitz S, Baruch L, Shapiro E, Segal E. Geometric constraints on neuronal connectivity facilitate a concise synaptic adhesive code. Proceedings of the National Academy of Sciences of the United States of America. 105: 9278-83. PMID 18583478 DOI: 10.1073/pnas.0712207105 |
1 |
|
| 2008 |
Wasserstrom A, Frumkin D, Adar R, Itzkovitz S, Stern T, Kaplan S, Shefer G, Shur I, Zangi L, Reizel Y, Harmelin A, Dor Y, Dekel N, Reisner Y, Benayahu D, ... ... Segal E, et al. Estimating cell depth from somatic mutations. Plos Computational Biology. 4: e1000058. PMID 18404205 DOI: 10.1371/journal.pcbi.1000058 |
1 |
|
| 2008 |
Wasserstrom A, Adar R, Shefer G, Frumkin D, Itzkovitz S, Stern T, Shur I, Zangi L, Kaplan S, Harmelin A, Reisner Y, Benayahu D, Tzahor E, Segal E, Shapiro E. Reconstruction of cell lineage trees in mice. Plos One. 3: e1939. PMID 18398465 DOI: 10.1371/journal.pone.0001939 |
1 |
|
| 2008 |
Wong DJ, Liu H, Ridky TW, Cassarino D, Segal E, Chang HY. Module map of stem cell genes guides creation of epithelial cancer stem cells. Cell Stem Cell. 2: 333-44. PMID 18397753 DOI: 10.1016/j.stem.2008.02.009 |
1 |
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| 2008 |
Minsky N, Shema E, Field Y, Schuster M, Segal E, Oren M. Monoubiquitinated H2B is associated with the transcribed region of highly expressed genes in human cells. Nature Cell Biology. 10: 483-8. PMID 18344985 DOI: 10.1038/ncb1712 |
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| 2008 |
Adler AS, Kawahara TL, Segal E, Chang HY. Reversal of aging by NFkappaB blockade. Cell Cycle (Georgetown, Tex.). 7: 556-9. PMID 18256548 DOI: 10.4161/cc.7.5.5490 |
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| 2008 |
Sinha S, Adler AS, Field Y, Chang HY, Segal E. Systematic functional characterization of cis-regulatory motifs in human core promoters. Genome Research. 18: 477-88. PMID 18256240 DOI: 10.1101/gr.6828808 |
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| 2008 |
Wong DJ, Nuyten DS, Regev A, Lin M, Adler AS, Segal E, van de Vijver MJ, Chang HY. Revealing targeted therapy for human cancer by gene module maps. Cancer Research. 68: 369-78. PMID 18199530 DOI: 10.1158/0008-5472.CAN-07-0382 |
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| 2008 |
Segal E, Raveh-Sadka T, Schroeder M, Unnerstall U, Gaul U. Predicting expression patterns from regulatory sequence in Drosophila segmentation. Nature. 451: 535-40. PMID 18172436 DOI: 10.1038/nature06496 |
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| 2007 |
Adler AS, Sinha S, Kawahara TL, Zhang JY, Segal E, Chang HY. Motif module map reveals enforcement of aging by continual NF-kappaB activity. Genes & Development. 21: 3244-57. PMID 18055696 DOI: 10.1101/gad.1588507 |
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| 2007 |
Kertesz M, Iovino N, Unnerstall U, Gaul U, Segal E. The role of site accessibility in microRNA target recognition. Nature Genetics. 39: 1278-84. PMID 17893677 DOI: 10.1038/ng2135 |
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| 2007 |
Wang H, Segal E, Ben-Hur A, Li QR, Vidal M, Koller D. InSite: a computational method for identifying protein-protein interaction binding sites on a proteome-wide scale. Genome Biology. 8: R192. PMID 17868464 DOI: 10.1186/gb-2007-8-9-r192 |
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| 2007 |
Rinn JL, Kertesz M, Wang JK, Squazzo SL, Xu X, Brugmann SA, Goodnough LH, Helms JA, Farnham PJ, Segal E, Chang HY. Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell. 129: 1311-23. PMID 17604720 DOI: 10.1016/j.cell.2007.05.022 |
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| 2007 |
Liu H, Adler AS, Segal E, Chang HY. A transcriptional program mediating entry into cellular quiescence. Plos Genetics. 3: e91. PMID 17559306 DOI: 10.1371/journal.pgen.0030091 |
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| 2007 |
Segal E, Sirlin CB, Ooi C, Adler AS, Gollub J, Chen X, Chan BK, Matcuk GR, Barry CT, Chang HY, Kuo MD. Decoding global gene expression programs in liver cancer by noninvasive imaging. Nature Biotechnology. 25: 675-80. PMID 17515910 DOI: 10.1038/nbt1306 |
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| 2007 |
Achiron A, Gurevich M, Snir Y, Segal E, Mandel M. Zinc-ion binding and cytokine activity regulation pathways predicts outcome in relapsing-remitting multiple sclerosis. Clinical and Experimental Immunology. 149: 235-42. PMID 17488294 DOI: 10.1111/j.1365-2249.2007.03405.x |
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| 2007 |
Amit I, Citri A, Shay T, Lu Y, Katz M, Zhang F, Tarcic G, Siwak D, Lahad J, Jacob-Hirsch J, Amariglio N, Vaisman N, Segal E, Rechavi G, Alon U, et al. A module of negative feedback regulators defines growth factor signaling. Nature Genetics. 39: 503-12. PMID 17322878 DOI: 10.1038/ng1987 |
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| 2006 |
Segal E, Fondufe-Mittendorf Y, Chen L, Thåström A, Field Y, Moore IK, Wang JP, Widom J. A genomic code for nucleosome positioning. Nature. 442: 772-8. PMID 16862119 DOI: 10.1038/nature04979 |
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| 2006 |
Keshet I, Schlesinger Y, Farkash S, Rand E, Hecht M, Segal E, Pikarski E, Young RA, Niveleau A, Cedar H, Simon I. Evidence for an instructive mechanism of de novo methylation in cancer cells. Nature Genetics. 38: 149-53. PMID 16444255 DOI: 10.1038/ng1719 |
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| 2006 |
Matias Y, Segal E, Vitter JS. Efficient bundle sorting Siam Journal On Computing. 36: 394-410. DOI: 10.1137/S0097539704446554 |
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| 2005 |
Battle A, Segal E, Koller D. Probabilistic discovery of overlapping cellular processes and their regulation. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 12: 909-27. PMID 16201912 DOI: 10.1089/cmb.2005.12.909 |
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| 2005 |
Segal E, Sharan R. A discriminative model for identifying spatial cis-regulatory modules Journal of Computational Biology. 12: 822-834. PMID 16108719 DOI: 10.1089/cmb.2005.12.822 |
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| 2005 |
Segal E, Friedman N, Kaminski N, Regev A, Koller D. From signatures to models: understanding cancer using microarrays. Nature Genetics. 37: S38-45. PMID 15920529 DOI: 10.1038/ng1561 |
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| 2005 |
Hartemink AJ, Segal E. Joint learning from multiple types of genomic data. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 445-6. PMID 15759649 |
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| 2005 |
Segal E, Pe'er D, Regev A, Koller D, Friedman N. Learning module networks Journal of Machine Learning Research. 6. |
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| 2005 |
Wang H, Segal E, Ben-Hur A, Koller D, Brutlag DL. Identifying protein-protein interaction sites on a genome-wide scale Advances in Neural Information Processing Systems. |
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| 2004 |
Rodwell GE, Sonu R, Zahn JM, Lund J, Wilhelmy J, Wang L, Xiao W, Mindrinos M, Crane E, Segal E, Myers BD, Brooks JD, Davis RW, Higgins J, Owen AB, et al. A transcriptional profile of aging in the human kidney. Plos Biology. 2: e427. PMID 15562319 DOI: 10.1371/journal.pbio.0020427 |
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| 2004 |
Segal E, Friedman N, Koller D, Regev A. A module map showing conditional activity of expression modules in cancer. Nature Genetics. 36: 1090-8. PMID 15448693 DOI: 10.1038/ng1434 |
0.96 |
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| 2004 |
Shapira M, Segal E, Botstein D. Disruption of yeast forkhead-associated cell cycle transcription by oxidative stress. Molecular Biology of the Cell. 15: 5659-69. PMID 15371544 DOI: 10.1091/mbc.E04-04-0340 |
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| 2004 |
Marion RM, Regev A, Segal E, Barash Y, Koller D, Friedman N, O'Shea EK. Sfp1 is a stress- and nutrient-sensitive regulator of ribosomal protein gene expression. Proceedings of the National Academy of Sciences of the United States of America. 101: 14315-22. PMID 15353587 DOI: 10.1073/pnas.0405353101 |
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| 2003 |
Stuart JM, Segal E, Koller D, Kim SK. A gene-coexpression network for global discovery of conserved genetic modules. Science (New York, N.Y.). 302: 249-55. PMID 12934013 DOI: 10.1126/science.1087447 |
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| 2003 |
Segal E, Yelensky R, Koller D. Genome-wide discovery of transcriptional modules from DNA sequence and gene expression. Bioinformatics (Oxford, England). 19: i273-82. PMID 12855470 |
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| 2003 |
Segal E, Wang H, Koller D. Discovering molecular pathways from protein interaction and gene expression data. Bioinformatics (Oxford, England). 19: i264-71. PMID 12855469 DOI: 10.1093/bioinformatics/btg1037 |
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| 2003 |
Segal E, Shapira M, Regev A, Pe'er D, Botstein D, Koller D, Friedman N. Module networks: identifying regulatory modules and their condition-specific regulators from gene expression data. Nature Genetics. 34: 166-76. PMID 12740579 DOI: 10.1038/ng1165 |
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| 2003 |
Segal E, Battle A, Koller D. Decomposing gene expression into cellular processes. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 89-100. PMID 12603020 |
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| 2002 |
Segal E, Barash Y, Simon I, Friedman N, Koller D. From promoter sequence to expression: A probabilistic framework Proceedings of the Annual International Conference On Computational Molecular Biology, Recomb. 263-272. |
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| 2002 |
Segal E, Koller D. Probabilistic hierarchical clustering for biological data Proceedings of the Annual International Conference On Computational Molecular Biology, Recomb. 273-280. |
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| 2001 |
Segal E, Taskar B, Gasch A, Friedman N, Koller D. Rich probabilistic models for gene expression. Bioinformatics (Oxford, England). 17: S243-52. PMID 11473015 |
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