Carlo C. Maley - Publications

Affiliations: 
Genomics and Computational Biology University of Pennsylvania, Philadelphia, PA, United States 
Area:
Genetics, Medicine and Surgery, Cell Biology

125 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Lakatos E, Gunasri V, Zapata L, Househam J, Heide T, Trahearn N, Swinyard O, Cisneros L, Lynn C, Mossner M, Kimberley C, Spiteri I, Cresswell GD, Llibre-Palomar G, Mitchison M, ... Maley CC, et al. Epigenome and early selection determine the tumour-immune evolutionary trajectory of colorectal cancer. Biorxiv : the Preprint Server For Biology. PMID 38405882 DOI: 10.1101/2024.02.12.579956  0.308
2023 Compton ZT, Mallo D, Maley CC. Stronger Together: Cancer Clones Cooperate to Alleviate Growth Barriers in Critical Cancer Progression Transitions. Cancer Research. 83: 4013-4014. PMID 37870405 DOI: 10.1158/0008-5472.CAN-23-3255  0.412
2023 Kapsetaki SE, Cisneros LH, Maley CC. Cell-in-cell phenomena across the tree of life. Research Square. PMID 37841858 DOI: 10.21203/rs.3.rs-3376588/v1  0.779
2023 Kapsetaki SE, Basile AJ, Compton ZT, Rupp SM, Duke EG, Boddy AM, Harrison TM, Sweazea KL, Maley CC. The relationship between diet, plasma glucose, and cancer prevalence across vertebrates. Biorxiv : the Preprint Server For Biology. PMID 37577544 DOI: 10.1101/2023.07.31.551378  0.799
2023 Compton Z, Harris V, Mellon W, Rupp S, Mallo D, Kapsetaki S, Wilmot M, Kennington R, Noble K, Baciu C, Ramirez L, Peraza A, Martins B, Sudhakar S, Aksoy S, ... ... Maley C, et al. Cancer Prevalence Across Vertebrates. Research Square. PMID 37461608 DOI: 10.21203/rs.3.rs-3117313/v1  0.817
2023 Kapsetaki SE, Fortunato A, Compton Z, Rupp SM, Nour Z, Riggs-Davis S, Stephenson D, Duke EG, Boddy AM, Harrison TM, Maley CC, Aktipis A. Is chimerism associated with cancer across the tree of life? Plos One. 18: e0287901. PMID 37384647 DOI: 10.1371/journal.pone.0287901  0.827
2023 Pradeu T, Daignan-Fornier B, Ewald A, Germain PL, Okasha S, Plutynski A, Benzekry S, Bertolaso M, Bissell M, Brown JS, Chin-Yee B, Chin-Yee I, Clevers H, Cognet L, Darrason M, ... ... Maley C, et al. Reuniting philosophy and science to advance cancer research. Biological Reviews of the Cambridge Philosophical Society. PMID 37157910 DOI: 10.1111/brv.12971  0.418
2023 AbdulJabbar K, Castillo SP, Hughes K, Davidson H, Boddy AM, Abegglen LM, Minoli L, Iussich S, Murchison EP, Graham TA, Spiro S, Maley CC, Aresu L, Palmieri C, Yuan Y. Bridging clinic and wildlife care with AI-powered pan-species computational pathology. Nature Communications. 14: 2408. PMID 37100774 DOI: 10.1038/s41467-023-37879-x  0.331
2023 Luebeck J, Ng AWT, Galipeau PC, Li X, Sanchez CA, Katz-Summercorn AC, Kim H, Jammula S, He Y, Lippman SM, Verhaak RGW, Maley CC, Alexandrov LB, Reid BJ, Fitzgerald RC, et al. Extrachromosomal DNA in the cancerous transformation of Barrett's oesophagus. Nature. PMID 37046089 DOI: 10.1038/s41586-023-05937-5  0.4
2023 Compton Z, Harris V, Mellon W, Rupp S, Mallo D, Kapsetaki SE, Wilmot M, Kennington R, Noble K, Baciu C, Ramirez L, Peraza A, Martins B, Sudhakar S, Aksoy S, ... ... Maley CC, et al. Cancer Prevalence Across Vertebrates. Biorxiv : the Preprint Server For Biology. PMID 36824942 DOI: 10.1101/2023.02.15.527881  0.814
2023 Kapsetaki SE, Compton Z, Dolan J, Harris VK, Rupp SM, Duke EG, Harrison TM, Aksoy S, Giraudeau M, Vincze O, McGraw KJ, Aktipis A, Tollis M, Boddy AM, Maley CC. Life history and cancer in birds: clutch size predicts cancer. Biorxiv : the Preprint Server For Biology. PMID 36824773 DOI: 10.1101/2023.02.11.528100  0.805
2022 Kapsetaki SE, Marquez Alcaraz G, Maley CC, Whisner CM, Aktipis A. Diet, Microbes, and Cancer Across the Tree of Life: a Systematic Review. Current Nutrition Reports. PMID 35704266 DOI: 10.1007/s13668-022-00420-5  0.816
2022 Paulson TG, Galipeau PC, Oman KM, Sanchez CA, Kuhner MK, Smith LP, Hadi K, Shah M, Arora K, Shelton J, Johnson M, Corvelo A, Maley CC, Yao X, Sanghvi R, et al. Somatic whole genome dynamics of precancer in Barrett's esophagus reveals features associated with disease progression. Nature Communications. 13: 2300. PMID 35484108 DOI: 10.1038/s41467-022-29767-7  0.368
2021 Vincze O, Colchero F, Lemaître JF, Conde DA, Pavard S, Bieuville M, Urrutia AO, Ujvari B, Boddy AM, Maley CC, Thomas F, Giraudeau M. Cancer risk across mammals. Nature. PMID 34937938 DOI: 10.1038/s41586-021-04224-5  0.436
2021 Fortunato A, Fleming A, Aktipis A, Maley CC. Upregulation of DNA repair genes and cell extrusion underpin the remarkable radiation resistance of Trichoplax adhaerens. Plos Biology. 19: e3001471. PMID 34788294 DOI: 10.1371/journal.pbio.3001471  0.664
2021 Winfrey P, Robertson C, Maley C, Aktipis A. ENDLESS FORMS MOST BEAUTIFUL: A GARDEN SHOWS THAT CANCER IS A PART OF LIFE. Leonardo (Oxford, England). 54: 398-401. PMID 34565895 DOI: 10.1162/leon_a_01915  0.739
2021 Tollis M, Ferris E, Campbell MS, Harris VK, Rupp SM, Harrison TM, Kiso WK, Schmitt DL, Garner MM, Athena Aktipis C, Maley CC, Boddy AM, Yandell M, Gregg C, Schiffman JD, et al. Elephant Genomes Reveal Accelerated Evolution in Mechanisms Underlying Disease Defenses. Molecular Biology and Evolution. PMID 33944920 DOI: 10.1093/molbev/msab127  0.724
2021 Dujon AM, Aktipis A, Alix-Panabières C, Amend SR, Boddy AM, Brown JS, Capp JP, DeGregori J, Ewald P, Gatenby R, Gerlinger M, Giraudeau M, Hamede RK, Hansen E, Kareva I, ... Maley CC, et al. Identifying key questions in the ecology and evolution of cancer. Evolutionary Applications. 14: 877-892. PMID 33897809 DOI: 10.1111/eva.13190  0.721
2020 Boddy AM, Abegglen LM, Aktipis A, Schiffman JD, Maley CC, Witte C. Does placental invasiveness lead to higher rates of malignant transformation in mammals?: Response to: 'Available data suggests positive relationship between placental invasion an malignancy'. Evolution, Medicine, and Public Health. 2020: 215-216. PMID 33214902 DOI: 10.1093/emph/eoaa025  0.606
2020 Boddy AM, Abegglen LM, Pessier AP, Aktipis A, Schiffman JD, Maley CC, Witte C. Lifetime cancer prevalence and life history traits in mammals. Evolution, Medicine, and Public Health. 2020: 187-195. PMID 33209304 DOI: 10.1093/Emph/Eoaa015  0.762
2020 Merlo LMF, Sprouffske K, Howard TC, Gardiner KL, Caulin AF, Blum SM, Evans P, Bedalov A, Sniegowski PD, Maley CC. Application of simultaneous selective pressures slows adaptation. Evolutionary Applications. 13: 1615-1625. PMID 32952608 DOI: 10.1111/Eva.13062  0.718
2020 Birtwell D, Luebeck G, Maley CC. The evolution of metapopulation dynamics and the number of stem cells in intestinal crypts and other tissue structures in multicellular bodies. Evolutionary Applications. 13: 1771-1783. PMID 32821281 DOI: 10.1111/Eva.13069  0.357
2020 Tollis M, Schneider-Utaka AK, Maley CC. The Evolution of Human Cancer Gene Duplications across Mammals. Molecular Biology and Evolution. PMID 32421773 DOI: 10.1093/Molbev/Msaa125  0.787
2020 Acar A, Nichol D, Fernandez-Mateos J, Cresswell GD, Barozzi I, Hong SP, Trahearn N, Spiteri I, Stubbs M, Burke R, Stewart A, Caravagna G, Werner B, Vlachogiannis G, Maley CC, et al. Exploiting evolutionary steering to induce collateral drug sensitivity in cancer. Nature Communications. 11: 1923. PMID 32317663 DOI: 10.1038/S41467-020-15596-Z  0.45
2020 Cresswell GD, Nichol D, Spiteri I, Tari H, Zapata L, Heide T, Maley CC, Magnani L, Schiavon G, Ashworth A, Barry P, Sottoriva A. Mapping the breast cancer metastatic cascade onto ctDNA using genetic and epigenetic clonal tracking. Nature Communications. 11: 1446. PMID 32221288 DOI: 10.1038/S41467-020-15047-9  0.487
2020 Chandrashekar P, Ahmadinejad N, Wang J, Sekulic A, Egan JB, Asmann YW, Kumar S, Maley C, Liu L. Somatic selection distinguishes oncogenes and tumor suppressor genes. Bioinformatics (Oxford, England). 36: 1712-1717. PMID 32176769 DOI: 10.1093/Bioinformatics/Btz851  0.413
2020 Ryser MD, Mallo D, Hall A, Hardman T, King LM, Tatishchev S, Sorribes IC, Maley CC, Marks JR, Hwang ES, Shibata D. Minimal barriers to invasion during human colorectal tumor growth. Nature Communications. 11: 1280. PMID 32152322 DOI: 10.1038/S41467-020-14908-7  0.361
2020 Phan T, Crook SM, Bryce AH, Maley CC, Kostelich EJ, Kuang Y. Review: Mathematical Modeling of Prostate Cancer and Clinical Application Applied Sciences. 10: 2721. DOI: 10.3390/App10082721  0.408
2020 Winfrey P, Robertson C, Maley C, Aktipis A. Endless Forms Most Beautiful: A Garden Shows That Cancer Is a Part of Life Leonardo. 1-8. DOI: 10.1162/Leon_A_01915  0.73
2020 Ryser MD, Sorribes IC, Greenwald M, Hall A, Mallo D, King LM, Hardman T, Simpson L, Maley CC, Marks JR, Shibata D, Hwang ES. Abstract 2683: Ductal carcinoma in situ is a multiclonal disease Cancer Research. 80: 2683-2683. DOI: 10.1158/1538-7445.Am2020-2683  0.398
2020 Fortunato A, Mallo D, King L, Hardman T, Hall A, Marks JR, Hwang SS, Maley CC. Abstract 2502: Genetic and functional heterogeneity of DCIS as predictors of invasive cancer Cancer Research. 80: 2502-2502. DOI: 10.1158/1538-7445.Am2020-2502  0.465
2019 Nawaz S, Trahearn NA, Heindl A, Banerjee S, Maley CC, Sottoriva A, Yuan Y. Analysis of tumour ecological balance reveals resource-dependent adaptive strategies of ovarian cancer. Ebiomedicine. PMID 31648981 DOI: 10.1016/J.Ebiom.2019.10.001  0.44
2019 May A, Narayanan S, Alcock J, Varsani A, Maley C, Aktipis A. Kombucha: a novel model system for cooperation and conflict in a complex multi-species microbial ecosystem. Peerj. 7: e7565. PMID 31534844 DOI: 10.7717/Peerj.7565  0.632
2019 Hou R, Mazurowski MA, Grimm LJ, Marks JR, King LM, Maley CC, Hwang ES, Lo JY. Prediction of Upstaged Ductal Carcinoma in situ Using Forced Labeling and Domain Adaptation. Ieee Transactions On Bio-Medical Engineering. PMID 31502960 DOI: 10.1109/Tbme.2019.2940195  0.31
2019 Maley CC, Shibata D. Cancer cell evolution through the ages. Science (New York, N.Y.). 365: 440-441. PMID 31371596 DOI: 10.1126/Science.Aay2859  0.47
2019 Tollis M, Robbins J, Webb AE, Kuderna LFK, Caulin AF, Garcia JD, Bèrubè M, Pourmand N, Marques-Bonet T, O'Connell MJ, Palsbøll PJ, Maley CC. Return to the sea, get huge, beat cancer: an analysis of cetacean genomes including an assembly for the humpback whale (Megaptera novaeangliae). Molecular Biology and Evolution. PMID 31070747 DOI: 10.1093/Molbev/Msz099  0.776
2019 Fortunato A, Mallo D, King L, Hardman T, Hall A, Marks J, Hwang S, Maley C. Abstract P3-06-12: Genetic heterogeneity of DCIS is a predictor of invasive cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-P3-06-12  0.466
2019 Hoefnagel SJM, Westra WM, Timmer MR, Martinez P, Klaver E, Lau CT, Calpe S, Sancho-Serra MdC, Straub D, Baker AM, Rygiel AM, Rosmolen WD, Meijer SL, ten Kate FJW, Dijkgraaf MGW, ... ... Maley CC, et al. O108 GENOMIC BIOMARKERS FOR CANCER RISK IN BARRETT’S ESOPHAGUS: AN UPDATE ON THE LONGITUDINAL DUTCH BARRETT’S ESOPHAGUS COHORT Diseases of the Esophagus. 32. DOI: 10.1093/Dote/Doz092.108  0.396
2019 Hoefnagel S, Westra WH, Timmer MR, Martinez P, Klaver E, Calpe S, del Carmen Sancho-Serra M, Straub D, Baker A, Rosmolen W, Meijer SL, Kate FT, Dijkgraaf M, Mallant-Hent R, Naber AH, ... ... Maley C, et al. Sa1135 – Genomic Biomarkers for Cancer Risk in Barrett's Esophagus: An Update on the Longitudinal Dutch Barrett's Esophagus Cohort Gastroenterology. 156: S-279-S-280. DOI: 10.1016/S0016-5085(19)37517-1  0.413
2018 Leong SP, Aktipis A, Maley C. Cancer initiation and progression within the cancer microenvironment. Clinical & Experimental Metastasis. PMID 29992410 DOI: 10.1007/S10585-018-9921-Y  0.765
2018 Barry P, Vatsiou A, Spiteri I, Nichol D, Cresswell GD, Acar A, Trahearn NA, Hrebien S, Garcia-Murillas I, Chkhaidze K, Ermini L, Said Huntingford I, Cottom H, Zabaglo L, Koelble K, ... ... Maley CC, et al. The spatio-temporal evolution of lymph node spread in early breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29891724 DOI: 10.1158/1078-0432.Ccr-17-3374  0.357
2018 Martinez P, Mallo D, Paulson TG, Li X, Sanchez CA, Reid BJ, Graham TA, Kuhner MK, Maley CC. Evolution of Barrett's esophagus through space and time at single-crypt and whole-biopsy levels. Nature Communications. 9: 794. PMID 29476056 DOI: 10.1038/S41467-017-02621-X  0.347
2018 Abegglen LM, Toruno C, Donovan LN, Robinson R, Goldfeder M, Couldwell G, Kiso WK, Schmitt DL, Caulin AF, Maley CC, Schroeder A, Schiffman JD. Abstract A25: Elephant p53 (EP53) enhances and restores p53-mediated apoptosis in human and canine osteosarcoma Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Sarcomas17-A25  0.327
2018 Fortunato A, King L, Mallo D, Hall A, Aktipis A, Marks J, Hwang S, Maley C. Abstract P2-05-05: Not presented Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P2-05-05  0.6
2018 Lo J, Grimm L, Mazurowski M, Baker J, Marks J, King L, Maley C, Hwang E, Shi B. Abstract GS5-04: Prediction of occult invasive disease in ductal carcinoma in situ using deep learning features Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-Gs5-04  0.323
2017 Chowell D, Napier J, Gupta R, Anderson KS, Maley CC, Wilson Sayres MA. Modeling the subclonal evolution of cancer cell populations. Cancer Research. PMID 29187407 DOI: 10.1158/0008-5472.Can-17-1229  0.405
2017 Aktipis A, Maley CC. Cooperation and cheating as innovation: insights from cellular societies. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 372. PMID 29061894 DOI: 10.1098/Rstb.2016.0421  0.667
2017 Maley CC, Aktipis A, Graham TA, Sottoriva A, Boddy AM, Janiszewska M, Silva AS, Gerlinger M, Yuan Y, Pienta KJ, Anderson KS, Gatenby R, Swanton C, Posada D, Wu CI, et al. Classifying the evolutionary and ecological features of neoplasms. Nature Reviews. Cancer. PMID 28912577 DOI: 10.1038/Nrc.2017.69  0.735
2017 Tollis M, Boddy AM, Maley CC. Peto's Paradox: how has evolution solved the problem of cancer prevention? Bmc Biology. 15: 60. PMID 28705195 DOI: 10.1186/S12915-017-0401-7  0.789
2017 Andor N, Maley CC, Ji HP. Genomic Instability in Cancer: Teetering on the Limit of Tolerance. Cancer Research. PMID 28432052 DOI: 10.1158/0008-5472.Can-16-1553  0.437
2017 Lote H, Spiteri I, Ermini L, Vatsiou A, Roy A, McDonald A, Maka N, Balsitis M, Bose N, Simbolo M, Mafficini A, Lampis A, Hahne JC, Trevisani F, Eltahir Z, ... ... Maley C, et al. Carbon dating cancer: defining the chronology of metastatic progression in colorectal cancer. Annals of Oncology : Official Journal of the European Society For Medical Oncology. PMID 28327965 DOI: 10.1093/Annonc/Mdx074  0.747
2017 Fortunato A, Boddy A, Mallo D, Aktipis A, Maley CC, Pepper JW. Natural Selection in Cancer Biology: From Molecular Snowflakes to Trait Hallmarks. Cold Spring Harbor Perspectives in Medicine. 7. PMID 28148564 DOI: 10.1101/Cshperspect.A029652  0.745
2017 Ding Y, Marks J, King L, Hall A, Mardis E, Rodrigo A, Maley C, Hwang E. Abstract P1-06-06: Evidence for tumor heterogeneity and clonal evolution during invasive progression of breast cancer Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P1-06-06  0.455
2017 Fortunato A, King L, Mallo D, Kovacheva V, Yuan Y, Boddy A, Graham T, Aktipis A, Mardis E, Hall A, Marks J, Hwang S, Maley C. Abstract P1-05-30: Genomic and microenvironmental intra-tumor heterogeneity in DCIS Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P1-05-30  0.641
2017 Andor N, Maley CC, Ji HP. Abstract 2921: Integrated exome- and single cell RNA-sequencing reveals a clone's genomic instability and multifaceted fitness Cancer Research. 77: 2921-2921. DOI: 10.1158/1538-7445.Am2017-2921  0.388
2017 Abegglen LM, Donovan LN, Couldwell G, Robinson R, Toruno C, Goldfeder M, Kiso WK, Schmitt DL, Caulin AF, Guillen KP, Welm BE, Maley CC, Schroeder A, Schiffman JD. Abstract 2153: Elephant p53 (EP53) expression induces apoptosis of human cancer cells Cancer Research. 77: 2153-2153. DOI: 10.1158/1538-7445.Am2017-2153  0.454
2017 Shi B, Grimm LJ, Mazurowski MA, Marks JR, King LM, Maley CC, Hwang ES, Lo JY. Can upstaging of ductal carcinoma in situ be predicted at biopsy by histologic and mammographic features Proceedings of Spie. 10134. DOI: 10.1117/12.2255847  0.31
2016 Martinez P, Timmer MR, Lau CT, Calpe S, Sancho-Serra Mdel C, Straub D, Baker AM, Meijer SL, Kate FJ, Mallant-Hent RC, Naber AH, van Oijen AH, Baak LC, Scholten P, Böhmer CJ, ... ... Maley CC, et al. Dynamic clonal equilibrium and predetermined cancer risk in Barrett's oesophagus. Nature Communications. 7: 12158. PMID 27538785 DOI: 10.1038/Ncomms12158  0.353
2016 Schiffman JD, Schmitt DL, Maley CC. TP53 Gene and Cancer Resistance in Elephants--Reply. Jama. 315: 1790-1. PMID 27115386 DOI: 10.1001/Jama.2016.0457  0.418
2016 Kostadinov R, Maley CC, Kuhner MK. Bulk Genotyping of Biopsies Can Create Spurious Evidence for Hetereogeneity in Mutation Content. Plos Computational Biology. 12: e1004413. PMID 27105344 DOI: 10.1371/Journal.Pcbi.1004413  0.712
2016 Chowell D, Boddy AM, Mallo D, Tollis M, Maley CC. When (distant) relatives stay too long: implications for cancer medicine. Genome Biology. 17: 34. PMID 26912072 DOI: 10.1186/S13059-016-0906-3  0.756
2016 King L, Marks J, Hall A, Temko D, Graham T, Mardis E, Maley C, Hwang E. Abstract P6-05-03: Genomic diversity of ductal carcinoma in situ (DCIS) as a driver of invasion and metastasis Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P6-05-03  0.458
2016 Abegglen LM, Robinson R, Donovan L, Caulin AF, Goldfeder M, Schroeder A, Maley CC, Schiffman JD. Abstract 3686: ElephantTP53(ep53) retrogene protein expression enhances cellular apoptosis in response to DNA damage Cancer Research. 76: 3686-3686. DOI: 10.1158/1538-7445.Am2016-3686  0.367
2016 Andor N, Graham TA, Jansen M, Xia LC, Aktipis A, Petritsch C, Ji HP, Maley CC. Abstract 2387: Pan-cancer analysis of clonal evolution reveals the costs and adaptive benefits of genomic instability Cancer Research. 76: 2387-2387. DOI: 10.1158/1538-7445.Am2016-2387  0.733
2016 Timmer MR, Martinez P, Lau L, Meijer SL, Ten Kate F, Mallant-Hent R, Naber AH, van Oijen MG, Baak LC, Scholten P, Böhmer C, Fockens P, Bergman J, Maley C, Graham TA, et al. 139 Longitudinal Single Cell Clonal Analysis Reveals Evolutionary Stasis and Re-Determined Malignant Potential in Non-Dysplastic Barrett's Esophagus Gastroenterology. 150: S34. DOI: 10.1016/S0016-5085(16)30240-2  0.32
2015 Andor N, Graham TA, Jansen M, Xia LC, Aktipis CA, Petritsch C, Ji HP, Maley CC. Pan-cancer analysis of the extent and consequences of intratumor heterogeneity. Nature Medicine. PMID 26618723 DOI: 10.1038/Nm.3984  0.452
2015 Abegglen LM, Caulin AF, Chan A, Lee K, Robinson R, Campbell MS, Kiso WK, Schmitt DL, Waddell PJ, Bhaskara S, Jensen ST, Maley CC, Schiffman JD. Potential Mechanisms for Cancer Resistance in Elephants and Comparative Cellular Response to DNA Damage in Humans. Jama. 1-11. PMID 26447779 DOI: 10.1001/Jama.2015.13134  0.384
2015 Maley CC, Koelble K, Natrajan R, Aktipis A, Yuan Y. An ecological measure of immune-cancer colocalization as a prognostic factor for breast cancer. Breast Cancer Research : Bcr. 17: 131. PMID 26395345 DOI: 10.1186/S13058-015-0638-4  0.727
2015 Li X, Paulson TG, Galipeau PC, Sanchez CA, Liu K, Kuhner MK, Maley CC, Self SG, Vaughan TL, Reid BJ, Blount PL. Assessment of esophageal adenocarcinoma risk using somatic chromosome alterations in longitudinal samples in Barrett's esophagus. Cancer Prevention Research (Philadelphia, Pa.). PMID 26130253 DOI: 10.1158/1940-6207.Capr-15-0130  0.461
2015 Timmer MR, Martinez P, Lau CT, Westra WM, Calpe S, Rygiel AM, Rosmolen WD, Meijer SL, Ten Kate FJ, Dijkgraaf MG, Mallant-Hent RC, Naber AH, van Oijen AH, Baak LC, Scholten P, ... ... Maley CC, et al. Derivation of genetic biomarkers for cancer risk stratification in Barrett's oesophagus: a prospective cohort study. Gut. PMID 26104750 DOI: 10.1136/Gutjnl-2015-309642  0.332
2015 Caulin AF, Graham TA, Wang LS, Maley CC. Solutions to Peto's paradox revealed by mathematical modelling and cross-species cancer gene analysis. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 370. PMID 26056366 DOI: 10.1098/Rstb.2014.0222  0.539
2015 Aktipis CA, Boddy AM, Jansen G, Hibner U, Hochberg ME, Maley CC, Wilkinson GS. Cancer across the tree of life: cooperation and cheating in multicellularity. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 370. PMID 26056363 DOI: 10.1098/Rstb.2014.0219  0.557
2015 Nunney L, Maley CC, Breen M, Hochberg ME, Schiffman JD. Peto's paradox and the promise of comparative oncology. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 370. PMID 26056361 DOI: 10.1098/Rstb.2014.0177  0.549
2015 Paguirigan AL, Smith J, Meshinchi S, Carroll M, Maley C, Radich JP. Single-cell genotyping demonstrates complex clonal diversity in acute myeloid leukemia. Science Translational Medicine. 7: 281re2. PMID 25834112 DOI: 10.1126/Scitranslmed.Aaa0763  0.43
2015 Walther V, Hiley CT, Shibata D, Swanton C, Turner PE, Maley CC. Can oncology recapitulate paleontology? Lessons from species extinctions. Nature Reviews. Clinical Oncology. 12: 273-85. PMID 25687908 DOI: 10.1038/Nrclinonc.2015.12  0.483
2015 Andor N, Graham TA, Petritsch C, Ji HP, Maley CC. Abstract A1-54: Pan-cancer analysis of the etiology and consequences of intratumor heterogeneity Cancer Research. 75. DOI: 10.1158/1538-7445.Transcagen-A1-54  0.392
2015 Andor N, Graham TA, Aktipis AC, Petritsch C, Ji HP, Maley CC. Abstract LB-163: Pan-cancer analysis of the causes and consequences of Intra-tumor heterogeneity Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-163  0.73
2014 Li X, Galipeau PC, Paulson TG, Sanchez CA, Arnaudo J, Liu K, Sather CL, Kostadinov RL, Odze RD, Kuhner MK, Maley CC, Self SG, Vaughan TL, Blount PL, Reid BJ. Temporal and spatial evolution of somatic chromosomal alterations: a case-cohort study of Barrett's esophagus. Cancer Prevention Research (Philadelphia, Pa.). 7: 114-27. PMID 24253313 DOI: 10.1158/1940-6207.Capr-13-0289  0.768
2013 Aktipis CA, Boddy AM, Gatenby RA, Brown JS, Maley CC. Life history trade-offs in cancer evolution. Nature Reviews. Cancer. 13: 883-92. PMID 24213474 DOI: 10.1038/Nrc3606  0.422
2013 Kostadinov RL, Kuhner MK, Li X, Sanchez CA, Galipeau PC, Paulson TG, Sather CL, Srivastava A, Odze RD, Blount PL, Vaughan TL, Reid BJ, Maley CC. NSAIDs modulate clonal evolution in Barrett's esophagus. Plos Genetics. 9: e1003553. PMID 23785299 DOI: 10.1371/Journal.Pgen.1003553  0.752
2013 Sprouffske K, Athena Aktipis C, Radich JP, Carroll M, Nedelcu AM, Maley CC. An evolutionary explanation for the presence of cancer nonstem cells in neoplasms. Evolutionary Applications. 6: 92-101. PMID 23397439 DOI: 10.1111/Eva.12030  0.789
2013 S Datta R, Gutteridge A, Swanton C, Maley CC, Graham TA. Modelling the evolution of genetic instability during tumour progression. Evolutionary Applications. 6: 20-33. PMID 23396531 DOI: 10.1111/Eva.12024  0.343
2012 Sprouffske K, Merlo LM, Gerrish PJ, Maley CC, Sniegowski PD. Cancer in light of experimental evolution. Current Biology : Cb. 22: R762-71. PMID 22975007 DOI: 10.1016/J.Cub.2012.06.065  0.8
2012 Roche B, Hochberg ME, Caulin AF, Maley CC, Gatenby RA, Misse D, Thomas F. Natural resistance to cancers: a Darwinian hypothesis to explain Peto's paradox. Bmc Cancer. 12: 387. PMID 22943484 DOI: 10.1186/1471-2407-12-387  0.499
2012 Greaves M, Maley CC. Clonal evolution in cancer. Nature. 481: 306-13. PMID 22258609 DOI: 10.1038/Nature10762  0.503
2012 Aktipis CA, Maley CC, Pepper JW. Dispersal evolution in neoplasms: the role of disregulated metabolism in the evolution of cell motility. Cancer Prevention Research (Philadelphia, Pa.). 5: 266-75. PMID 21930797 DOI: 10.1158/1940-6207.Capr-11-0004  0.403
2012 Lui N, Caulin A, Graham T, Jablons D, Maley C. Within-tumor genetic diversity in lung cancer Journal of the American College of Surgeons. 215: S38. DOI: 10.1016/J.Jamcollsurg.2012.06.116  0.401
2011 Martens EA, Kostadinov R, Maley CC, Hallatschek O. Spatial structure increases the waiting time for cancer. New Journal of Physics. 13. PMID 22707911 DOI: 10.1088/1367-2630/13/11/115014  0.804
2011 Aktipis CA, Kwan VS, Johnson KA, Neuberg SL, Maley CC. Overlooking evolution: a systematic analysis of cancer relapse and therapeutic resistance research. Plos One. 6: e26100. PMID 22125594 DOI: 10.1371/Journal.Pone.0026100  0.411
2011 Merlo LM, Kosoff RE, Gardiner KL, Maley CC. An in vitro co-culture model of esophageal cells identifies ascorbic acid as a modulator of cell competition. Bmc Cancer. 11: 461. PMID 22026449 DOI: 10.1186/1471-2407-11-461  0.359
2011 Chen J, Sprouffske K, Huang Q, Maley CC. Solving the puzzle of metastasis: the evolution of cell migration in neoplasms. Plos One. 6: e17933. PMID 21556134 DOI: 10.1371/Journal.Pone.0017933  0.738
2011 Reid BJ, Kostadinov R, Maley CC. New strategies in Barrett's esophagus: integrating clonal evolutionary theory with clinical management. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 3512-9. PMID 21498395 DOI: 10.1158/1078-0432.Ccr-09-2358  0.739
2011 Sprouffske K, Pepper JW, Maley CC. Accurate reconstruction of the temporal order of mutations in neoplastic progression. Cancer Prevention Research (Philadelphia, Pa.). 4: 1135-44. PMID 21490131 DOI: 10.1158/1940-6207.Capr-10-0374  0.761
2011 Caulin AF, Maley CC. Peto's Paradox: evolution's prescription for cancer prevention. Trends in Ecology & Evolution. 26: 175-82. PMID 21296451 DOI: 10.1016/J.Tree.2011.01.002  0.549
2011 Maley CC, Szabo E, Reid BJ. Somatic evolution in neoplastic progression and cancer prevention Pre-Invasive Disease: Pathogenesis and Clinical Management. 111-127. DOI: 10.1007/978-1-4419-6694-0_7  0.37
2010 Merlo LM, Shah NA, Li X, Blount PL, Vaughan TL, Reid BJ, Maley CC. A comprehensive survey of clonal diversity measures in Barrett's esophagus as biomarkers of progression to esophageal adenocarcinoma. Cancer Prevention Research (Philadelphia, Pa.). 3: 1388-97. PMID 20947487 DOI: 10.1158/1940-6207.Capr-10-0108  0.403
2010 Merlo LM, Wang LS, Pepper JW, Rabinovitch PS, Maley CC. Polyploidy, aneuploidy and the evolution of cancer. Advances in Experimental Medicine and Biology. 676: 1-13. PMID 20687466 DOI: 10.1007/978-1-4419-6199-0_1  0.555
2010 Lai LA, Kostadinov R, Barrett MT, Peiffer DA, Pokholok D, Odze R, Sanchez CA, Maley CC, Reid BJ, Gunderson KL, Rabinovitch PS. Deletion at fragile sites is a common and early event in Barrett's esophagus. Molecular Cancer Research : McR. 8: 1084-94. PMID 20647332 DOI: 10.1158/1541-7786.Mcr-09-0529  0.735
2010 Pavlov K, Maley CC. New models of neoplastic progression in Barrett's oesophagus. Biochemical Society Transactions. 38: 331-6. PMID 20298178 DOI: 10.1042/Bst0380331  0.346
2010 Cairo MS, Jordan CT, Maley CC, Chao C, Melnick A, Armstrong SA, Shlomchik W, Molldrem J, Ferrone S, Mackall C, Zitvogel L, Bishop MR, Giralt SA, June CH. NCI first International Workshop on the biology, prevention, and treatment of relapse after allogeneic hematopoietic stem cell transplantation: report from the committee on the biological considerations of hematological relapse following allogeneic stem cell transplantation unrelated to graft-versus-tumor effects: state of the science. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 16: 709-28. PMID 20227509 DOI: 10.1016/J.Bbmt.2010.03.002  0.391
2010 Merlo LM, Maley CC. The role of genetic diversity in cancer. The Journal of Clinical Investigation. 120: 401-3. PMID 20101092 DOI: 10.1172/Jci42088  0.479
2010 Aktipis CA, Johnson K, Dong E, Kwan VSY, Neuberg SL, Maley CC. Abstract B2: Conceptual barriers in cancer prevention research Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-10-B2  0.52
2010 Kostadinov R, Sprouffske K, Merlo L, Kuhner M, Maley C. Abstract 101: The mechanism of clonal expansion determines the tempo and mode of neoplastic progression in Barrett's esophagus Cancer Research. 70: 101-101. DOI: 10.1158/1538-7445.Am10-101  0.786
2009 Pepper JW, Scott Findlay C, Kassen R, Spencer SL, Maley CC. Cancer research meets evolutionary biology. Evolutionary Applications. 2: 62-70. PMID 25567847 DOI: 10.1111/J.1752-4571.2008.00063.X  0.513
2009 Paulson TG, Maley CC, Li X, Li H, Sanchez CA, Chao DL, Odze RD, Vaughan TL, Blount PL, Reid BJ. Chromosomal instability and copy number alterations in Barrett's esophagus and esophageal adenocarcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 3305-14. PMID 19417022 DOI: 10.1158/1078-0432.Ccr-08-2494  0.379
2008 Li X, Galipeau PC, Sanchez CA, Blount PL, Maley CC, Arnaudo J, Peiffer DA, Pokholok D, Gunderson KL, Reid BJ. Single nucleotide polymorphism-based genome-wide chromosome copy change, loss of heterozygosity, and aneuploidy in Barrett's esophagus neoplastic progression. Cancer Prevention Research (Philadelphia, Pa.). 1: 413-23. PMID 19138988 DOI: 10.1158/1940-6207.Capr-08-0121  0.315
2008 Chao DL, Eck JT, Brash DE, Maley CC, Luebeck EG. Preneoplastic lesion growth driven by the death of adjacent normal stem cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 15034-9. PMID 18815380 DOI: 10.1073/Pnas.0802211105  0.327
2008 Maley C. Abstract CN12-01: Clonal evolution over time in Barrett's Esophagus Cancer Prevention Research. 1. DOI: 10.1158/1940-6207.Prev-08-Cn12-01  0.452
2008 Kostadinov R, Li X, Paulson T, Galipeau P, Reid B, Maley C. Abstract B48: Cross sectional analysis of copy loss in Barrett’s Esophagus Cancer Prevention Research. 1. DOI: 10.1158/1940-6207.Prev-08-B48  0.307
2007 Pepper JW, Sprouffske K, Maley CC. Animal cell differentiation patterns suppress somatic evolution. Plos Computational Biology. 3: e250. PMID 18085819 DOI: 10.1371/Journal.Pcbi.0030250  0.738
2007 Kelloff GJ, Sullivan DC, Baker H, Clarke LP, Nordstrom R, Tatum JL, Dorfman GS, Jacobs P, Berg CD, Pomper MG, Birrer MJ, Tempero M, Higley HR, Petty BG, Sigman CC, ... Maley C, et al. Workshop on imaging science development for cancer prevention and preemption. Cancer Biomarkers : Section a of Disease Markers. 3: 1-33. PMID 17655039 DOI: 10.3233/Cbm-2007-3101  0.34
2007 Maley CC. Open questions in oesophageal adenocarcinogenesis. Gut. 56: 897-8. PMID 17566022 DOI: 10.1136/Gut.2006.117135  0.359
2007 Lai LA, Paulson TG, Li X, Sanchez CA, Maley C, Odze RD, Reid BJ, Rabinovitch PS. Increasing genomic instability during premalignant neoplastic progression revealed through high resolution array-CGH. Genes, Chromosomes & Cancer. 46: 532-42. PMID 17330261 DOI: 10.1002/Gcc.20435  0.369
2007 Galipeau PC, Li X, Blount PL, Maley CC, Sanchez CA, Odze RD, Ayub K, Rabinovitch PS, Vaughan TL, Reid BJ. NSAIDs modulate CDKN2A, TP53, and DNA content risk for progression to esophageal adenocarcinoma. Plos Medicine. 4: e67. PMID 17326708 DOI: 10.1371/Journal.Pmed.0040067  0.306
2007 Maley CC. Multistage carcinogenesis in Barrett's esophagus. Cancer Letters. 245: 22-32. PMID 16713672 DOI: 10.1016/J.Canlet.2006.03.018  0.398
2006 Merlo LM, Pepper JW, Reid BJ, Maley CC. Cancer as an evolutionary and ecological process. Nature Reviews. Cancer. 6: 924-35. PMID 17109012 DOI: 10.1038/Nrc2013  0.535
2006 Chao DL, Maley CC, Wu X, Farrow DC, Galipeau PC, Sanchez CA, Paulson TG, Rabinovitch PS, Reid BJ, Spitz MR, Vaughan TL. Mutagen sensitivity and neoplastic progression in patients with Barrett's esophagus: a prospective analysis. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 15: 1935-40. PMID 17035402 DOI: 10.1158/1055-9965.Epi-06-0492  0.403
2006 Kelloff GJ, Lippman SM, Dannenberg AJ, Sigman CC, Pearce HL, Reid BJ, Szabo E, Jordan VC, Spitz MR, Mills GB, Papadimitrakopoulou VA, Lotan R, Aggarwal BB, Bresalier RS, Kim J, ... ... Maley CC, et al. Progress in chemoprevention drug development: the promise of molecular biomarkers for prevention of intraepithelial neoplasia and cancer--a plan to move forward. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 3661-97. PMID 16778094 DOI: 10.1158/1078-0432.Ccr-06-1104  0.303
2006 Maley CC, Galipeau PC, Finley JC, Wongsurawat VJ, Li X, Sanchez CA, Paulson TG, Blount PL, Risques RA, Rabinovitch PS, Reid BJ. Genetic clonal diversity predicts progression to esophageal adenocarcinoma. Nature Genetics. 38: 468-73. PMID 16565718 DOI: 10.1038/Ng1768  0.491
2006 Wongsurawat VJ, Finley JC, Galipeau PC, Sanchez CA, Maley CC, Li X, Blount PL, Odze RD, Rabinovitch PS, Reid BJ. Genetic mechanisms of TP53 loss of heterozygosity in Barrett's esophagus: implications for biomarker validation. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 15: 509-16. PMID 16537709 DOI: 10.1158/1055-9965.Epi-05-0246  0.307
2005 Maley CC, Reid BJ. Natural selection in neoplastic progression of Barrett's esophagus. Seminars in Cancer Biology. 15: 474-83. PMID 16043360 DOI: 10.1016/J.Semcancer.2005.06.004  0.443
2004 Maley CC, Galipeau PC, Li X, Sanchez CA, Paulson TG, Blount PL, Reid BJ. The combination of genetic instability and clonal expansion predicts progression to esophageal adenocarcinoma. Cancer Research. 64: 7629-33. PMID 15492292 DOI: 10.1158/0008-5472.Can-04-1738  0.396
2002 Maley CC. Cancer: The Evolutionary Legacy Heredity. 88: 219-219. DOI: 10.1038/Sj.Hdy.6800053  0.528
2000 Maley CC, Forrest S. Exploring the relationship between neutral and selective mutations in cancer Artificial Life. 6: 325-345. PMID 11348585 DOI: 10.1162/106454600300103665  0.459
2000 Robeck HE, Maley CC, Donoghue MJ. Taxonomy and temporal diversity patterns Paleobiology. 26: 171-187. DOI: 10.1666/0094-8373(2000)026<0171:Tatdp>2.0.Co;2  0.504
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