Patrick Y. Jay - Publications

Biology & Biomedical Sciences (Computational Biology) Washington University, Saint Louis, St. Louis, MO 
Bioinformatics, Molecular Biology

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Panzer AA, Regmi SD, Cormier D, Danzo MT, Chen ID, Winston JB, Hutchinson AK, Salm D, Schulkey CE, Cochran RS, Wilson DB, Jay PY. Nkx2-5 and Sarcospan genetically interact in the development of the muscular ventricular septum of the heart. Scientific Reports. 7: 46438. PMID 28406175 DOI: 10.1038/srep46438  0.64
2016 Jay PY, Akhirome E, Magnan RA, Zhang MR, Kang L, Qin Y, Ugwu N, Regmi SD, Nogee JM, Cheverud JM. Transgenerational cardiology: One way to a baby's heart is through the mother. Molecular and Cellular Endocrinology. PMID 27555292 DOI: 10.1016/j.mce.2016.08.029  0.64
2015 Liu Z, Brunskill E, Varnum-Finney B, Zhang C, Zhang A, Jay PY, Bernstein I, Morimoto M, Kopan R. The intracellular domains of Notch1 and Notch2 are functionally equivalent during development and carcinogenesis. Development (Cambridge, England). 142: 2452-63. PMID 26062937 DOI: 10.1242/dev.125492  0.64
2015 Meyers JD, Jay PY, Rentschler S. Reprogramming the conduction system: Onward toward a biological pacemaker. Trends in Cardiovascular Medicine. PMID 25937044 DOI: 10.1016/j.tcm.2015.03.015  0.64
2015 Akhirome E, Jay PY. Rhythm genes sing more than one tune: noncanonical functions of cardiac ion channels. Circulation. Arrhythmia and Electrophysiology. 8: 261-2. PMID 25900989 DOI: 10.1161/CIRCEP.115.002834  0.64
2015 Schulkey CE, Regmi SD, Magnan RA, Danzo MT, Luther H, Hutchinson AK, Panzer AA, Grady MM, Wilson DB, Jay PY. The maternal-age-associated risk of congenital heart disease is modifiable. Nature. 520: 230-3. PMID 25830876 DOI: 10.1038/nature14361  0.64
2015 Schillebeeckx M, Pihlajoki M, Gretzinger E, Yang W, Thol F, Hiller T, Löbs AK, Röhrig T, Schrade A, Cochran R, Jay PY, Heikinheimo M, Mitra RD, Wilson DB. Novel markers of gonadectomy-induced adrenocortical neoplasia in the mouse and ferret. Molecular and Cellular Endocrinology. 399: 122-30. PMID 25289806 DOI: 10.1016/j.mce.2014.09.029  0.64
2014 Prendiville T, Jay PY, Pu WT. Insights into the genetic structure of congenital heart disease from human and murine studies on monogenic disorders. Cold Spring Harbor Perspectives in Medicine. 4. PMID 25274754 DOI: 10.1101/cshperspect.a013946  0.64
2014 Nguyen HH, Jay PY. A single misstep in cardiac development explains the co-occurrence of tetralogy of fallot and complete atrioventricular septal defect in Down syndrome. The Journal of Pediatrics. 165: 194-6. PMID 24721467 DOI: 10.1016/j.jpeds.2014.02.065  0.64
2014 Sanchez Mejia AA, Simpson KE, Hildebolt CF, Pahl E, Matthews KL, Rainey CA, Canter CE, Jay PY, Johnson MC. Tissue Doppler septal Tei index indicates severity of illness in pediatric patients with congestive heart failure. Pediatric Cardiology. 35: 411-8. PMID 24061276 DOI: 10.1007/s00246-013-0794-1  0.64
2014 Udager AM, Prakash A, Saenz DA, Schinke M, Moriguchi T, Jay PY, Lim KC, Engel JD, Gumucio DL. Proper development of the outer longitudinal smooth muscle of the mouse pylorus requires Nkx2-5 and Gata3 Gastroenterology. 146: 157-165.e10. DOI: 10.1053/j.gastro.2013.10.008  0.64
2013 Chen IB, Rathi VK, DeAndrade DS, Jay PY. Association of genes with physiological functions by comparative analysis of pooled expression microarray data. Physiological Genomics. 45: 69-78. PMID 23170034 DOI: 10.1152/physiolgenomics.00116.2012  0.64
2012 Winston JB, Schulkey CE, Chen IB, Regmi SD, Efimova M, Erlich JM, Green CA, Aluko A, Jay PY. Complex trait analysis of ventricular septal defects caused by Nkx2-5 mutation. Circulation. Cardiovascular Genetics. 5: 293-300. PMID 22534315 DOI: 10.1161/CIRCGENETICS.111.961136  0.64
2012 Krachulec J, Vetter M, Schrade A, Löbs AK, Bielinska M, Cochran R, Kyrönlahti A, Pihlajoki M, Parviainen H, Jay PY, Heikinheimo M, Wilson DB. GATA4 is a critical regulator of gonadectomy-induced adrenocortical tumorigenesis in mice. Endocrinology. 153: 2599-611. PMID 22461617 DOI: 10.1210/en.2011-2135  0.64
2012 Kaur K, Parra S, Chen R, Charbeneau RA, Wade SM, Jay PY, Neubig RR. Gαi2 signaling: friend or foe in cardiac injury and heart failure? Naunyn-Schmiedeberg's Archives of Pharmacology. 385: 443-53. PMID 22411356 DOI: 10.1007/s00210-011-0705-z  0.64
2012 Yang KC, Jay PY, McMullen JR, Nerbonne JM. Enhanced cardiac PI3Kα signalling mitigates arrhythmogenic electrical remodelling in pathological hypertrophy and heart failure. Cardiovascular Research. 93: 252-62. PMID 22038742 DOI: 10.1093/cvr/cvr283  0.64
2011 Mitra MS, Schilling JD, Wang X, Jay PY, Huss JM, Su X, Finck BN. Cardiac lipin 1 expression is regulated by the peroxisome proliferator activated receptor γ coactivator 1α/estrogen related receptor axis. Journal of Molecular and Cellular Cardiology. 51: 120-8. PMID 21549711 DOI: 10.1016/j.yjmcc.2011.04.009  0.64
2011 Vyas AK, Yang KC, Woo D, Tzekov A, Kovacs A, Jay PY, Hruz PW. Exenatide improves glucose homeostasis and prolongs survival in a murine model of dilated cardiomyopathy. Plos One. 6: e17178. PMID 21359201 DOI: 10.1371/journal.pone.0017178  0.64
2011 Kyrönlahti A, Vetter M, Euler R, Bielinska M, Jay PY, Anttonen M, Heikinheimo M, Wilson DB. GATA4 deficiency impairs ovarian function in adult mice. Biology of Reproduction. 84: 1033-44. PMID 21248289 DOI: 10.1095/biolreprod.110.086850  0.64
2010 Yang KC, Foeger NC, Marionneau C, Jay PY, McMullen JR, Nerbonne JM. Homeostatic regulation of electrical excitability in physiological cardiac hypertrophy. The Journal of Physiology. 588: 5015-32. PMID 20974681 DOI: 10.1113/jphysiol.2010.197418  0.64
2010 Winston JB, Erlich JM, Green CA, Aluko A, Kaiser KA, Takematsu M, Barlow RS, Sureka AO, LaPage MJ, Janss LL, Jay PY. Heterogeneity of genetic modifiers ensures normal cardiac development. Circulation. 121: 1313-21. PMID 20212279 DOI: 10.1161/CIRCULATIONAHA.109.887687  0.64
2009 Ng A, Wong M, Viviano B, Erlich JM, Alba G, Pflederer C, Jay PY, Saunders S. Loss of glypican-3 function causes growth factor-dependent defects in cardiac and coronary vascular development. Developmental Biology. 335: 208-15. PMID 19733558 DOI: 10.1016/j.ydbio.2009.08.029  0.64
2009 Zhang B, Chang J, Fu M, Huang J, Kashyap R, Salavaggione E, Jain S, Kulkarni S, Shashikant K, Deardorff MA, Uzielli ML, Dorsett D, Beebe DC, Jay PY, Heuckeroth RO, et al. Dosage effects of cohesin regulatory factor PDS5 on mammalian development: implications for cohesinopathies. Plos One. 4: e5232. PMID 19412548 DOI: 10.1371/journal.pone.0005232  0.64
2009 Sabirzhanova I, Sabirzhanov B, Bjordahl J, Brandt J, Jay PY, Clark TG. Activation of Tolloid-like 1 gene expression by the cardiac specific homeobox gene Nkx2-5. Development, Growth & Differentiation. 51: 403-10. PMID 19366374 DOI: 10.1111/j.1440-169X.2009.01097.x  0.64
2008 Jay PY. The 16th Asian Pacific Congress of Cardiology (APCC). Idrugs : the Investigational Drugs Journal. 11: 181-3. PMID 18311653  0.64
2008 Hruz PW, Yan Q, Struthers H, Jay PY. HIV protease inhibitors that block GLUT4 precipitate acute, decompensated heart failure in a mouse model of dilated cardiomyopathy. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 2161-7. PMID 18256305 DOI: 10.1096/fj.07-102269  0.64
2007 Jay PY. Genetic wiring diagram of the cardiac conduction system. Circulation. 116: 2520-2. PMID 18040037 DOI: 10.1161/CIRCULATIONAHA.107.737973  0.64
2007 Zhang B, Jain S, Song H, Fu M, Heuckeroth RO, Erlich JM, Jay PY, Milbrandt J. Mice lacking sister chromatid cohesion protein PDS5B exhibit developmental abnormalities reminiscent of Cornelia de Lange syndrome. Development (Cambridge, England). 134: 3191-201. PMID 17652350 DOI: 10.1242/dev.005884  0.64
2007 Bielinska M, Jay PY, Erlich JM, Mannisto S, Urban Z, Heikinheimo M, Wilson DB. Molecular genetics of congenital diaphragmatic defects. Annals of Medicine. 39: 261-74. PMID 17558598 DOI: 10.1080/07853890701326883  0.64
2007 McMullen JR, Jay PY. PI3K(p110alpha) inhibitors as anti-cancer agents: minding the heart. Cell Cycle (Georgetown, Tex.). 6: 910-3. PMID 17404510  0.64
2007 McMullen JR, Amirahmadi F, Woodcock EA, Schinke-Braun M, Bouwman RD, Hewitt KA, Mollica JP, Zhang L, Zhang Y, Shioi T, Buerger A, Izumo S, Jay PY, Jennings GL. Protective effects of exercise and phosphoinositide 3-kinase(p110alpha) signaling in dilated and hypertrophic cardiomyopathy. Proceedings of the National Academy of Sciences of the United States of America. 104: 612-7. PMID 17202264 DOI: 10.1073/pnas.0606663104  0.64
2007 Jay PY, Bielinska M, Erlich JM, Mannisto S, Pu WT, Heikinheimo M, Wilson DB. Impaired mesenchymal cell function in Gata4 mutant mice leads to diaphragmatic hernias and primary lung defects. Developmental Biology. 301: 602-14. PMID 17069789 DOI: 10.1016/j.ydbio.2006.09.050  0.64
2006 Buerger A, Rozhitskaya O, Sherwood MC, Dorfman AL, Bisping E, Abel ED, Pu WT, Izumo S, Jay PY. Dilated cardiomyopathy resulting from high-level myocardial expression of Cre-recombinase. Journal of Cardiac Failure. 12: 392-8. PMID 16762803 DOI: 10.1016/j.cardfail.2006.03.002  0.64
2005 Jay PY, Rozhitskaya O, Tarnavski O, Sherwood MC, Dorfman AL, Lu Y, Ueyama T, Izumo S. Haploinsufficiency of the cardiac transcription factor Nkx2-5 variably affects the expression of putative target genes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1495-7. PMID 15972800 DOI: 10.1096/fj.04-3064fje  0.64
2005 Jay PY, Maguire CT, Wakimoto H, Izumo S, Berul CI. Absence of Msx2 does not affect cardiac conduction or rescue conduction defects associated with Nkx2-5 mutation. Journal of Cardiovascular Electrophysiology. 16: 82-5. PMID 15673394 DOI: 10.1046/j.1540-8167.2005.04365.x  0.64
2004 Harris BS, Jay PY, Rackley MS, Izumo S, O'brien TX, Gourdie RG. Transcriptional regulation of cardiac conduction system development: 2004 FASEB cardiac conduction system minimeeting, Washington, DC. The Anatomical Record. Part a, Discoveries in Molecular, Cellular, and Evolutionary Biology. 280: 1036-45. PMID 15368344 DOI: 10.1002/ar.a.20101  0.64
2004 Jay PY, Harris BS, Buerger A, Rozhitskaya O, Maguire CT, Barbosky LA, McCusty E, Berul CI, O'brien TX, Gourdie RG, Izumo S. Function follows form: cardiac conduction system defects in Nkx2-5 mutation. The Anatomical Record. Part a, Discoveries in Molecular, Cellular, and Evolutionary Biology. 280: 966-72. PMID 15368343 DOI: 10.1002/ar.a.20102  0.64
2004 Jay PY, Harris BS, Maguire CT, Buerger A, Wakimoto H, Tanaka M, Kupershmidt S, Roden DM, Schultheiss TM, O'Brien TX, Gourdie RG, Berul CI, Izumo S. Nkx2-5 mutation causes anatomic hypoplasia of the cardiac conduction system. The Journal of Clinical Investigation. 113: 1130-7. PMID 15085192 DOI: 10.1172/JCI19846  0.64
2003 Jay PY, Berul CI, Tanaka M, Ishii M, Kurachi Y, Izumo S. Cardiac conduction and arrhythmia: insights from Nkx2.5 mutations in mouse and humans. Novartis Foundation Symposium. 250: 227-38; discussion 2. PMID 12956333  0.64
2002 Tanaka M, Berul CI, Ishii M, Jay PY, Wakimoto H, Douglas P, Yamasaki N, Kawamoto T, Gehrmann J, Maguire CT, Schinke M, Seidman CE, Seidman JG, Kurachi Y, Izumo S. A mouse model of congenital heart disease: Cardiac arrhythmias and atrial septal defect caused by haploinsufficiency of the cardiac transcription factor Csx/Nkx2.5 Cold Spring Harbor Symposia On Quantitative Biology. 67: 317-325. PMID 12858555  0.64
2002 Jay PY, Izumo S. Elucidating the molecular and genetic interactions responsible for congenital heart disease. Pediatric Research. 51: 127. PMID 11809903 DOI: 10.1203/00006450-200202000-00001  0.64
1999 Elson EL, Felder SF, Jay PY, Kolodney MS, Pasternak C. Forces in cell locomotion. Biochemical Society Symposium. 65: 299-314. PMID 10320946  0.64
1998 Luna EJ, Hitt AL, Shutt D, Wessels D, Soll D, Jay P, Hug C, Elson EL, Vesley A, Downey GP, Wang M, Block SM, Sigurdson W, Sachs F. Role of ponticulin in pseudopod dynamics, cell-cell adhesion, and mechanical stability of an amoeboid membrane skeleton. The Biological Bulletin. 194: 345-6; discussion 34. PMID 11536879  0.64
1995 Hug C, Jay PY, Reddy I, McNally JG, Bridgman PC, Elson EL, Cooper JA. Capping protein levels influence actin assembly and cell motility in dictyostelium. Cell. 81: 591-600. PMID 7758113 DOI: 10.1016/0092-8674(95)90080-2  0.64
1995 Jay PY, Pham PA, Wong SA, Elson EL. A mechanical function of myosin II in cell motility. Journal of Cell Science. 108: 387-93. PMID 7738114  0.64
1993 Jay PY, Pasternak C, Elson EL. Studies of mechanical aspects of amoeboid locomotion Blood Cells. 19: 375-388. PMID 8312570  0.64
1992 Jay PY, Elson EL. Surface particle transport mechanism independent of myosin II in Dictyostelium Nature. 356: 438-440. PMID 1557126  0.64
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