David A. Orlando, Ph.D. - Publications

Affiliations: 
2009 Computational Biology and Bioinformatics Duke University, Durham, NC 
Area:
Bioinformatics, Genetics

22 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Orlando DA, Chen MW, Brown VE, Solanki S, Choi YJ, Olson ER, Fritz CC, Bradner JE, Guenther MG. Quantitative ChIP-Seq normalization reveals global modulation of the epigenome Cell Reports. 9: 1163-1170. DOI: 10.1016/j.celrep.2014.10.018  1
2013 Dowen JM, Bilodeau S, Orlando DA, Hübner MR, Abraham BJ, Spector DL, Young RA. Multiple structural maintenance of chromosome complexes at transcriptional regulatory elements. Stem Cell Reports. 1: 371-8. PMID 24286025 DOI: 10.1016/j.stemcr.2013.09.002  1
2013 Li Y, Wang H, Muffat J, Cheng AW, Orlando DA, Lovén J, Kwok SM, Feldman DA, Bateup HS, Gao Q, Hockemeyer D, Mitalipova M, Lewis CA, Vander Heiden MG, Sur M, et al. Global transcriptional and translational repression in human-embryonic-stem-cell-derived Rett syndrome neurons. Cell Stem Cell. 13: 446-58. PMID 24094325 DOI: 10.1016/j.stem.2013.09.001  1
2013 Lovén J, Hoke HA, Lin CY, Lau A, Orlando DA, Vakoc CR, Bradner JE, Lee TI, Young RA. Selective inhibition of tumor oncogenes by disruption of super-enhancers. Cell. 153: 320-34. PMID 23582323 DOI: 10.1016/j.cell.2013.03.036  1
2013 Whyte WA, Orlando DA, Hnisz D, Abraham BJ, Lin CY, Kagey MH, Rahl PB, Lee TI, Young RA. Master transcription factors and mediator establish super-enhancers at key cell identity genes. Cell. 153: 307-19. PMID 23582322 DOI: 10.1016/j.cell.2013.03.035  1
2013 Guo X, Bernard A, Orlando DA, Haase SB, Hartemink AJ. Branching process deconvolution algorithm reveals a detailed cell-cycle transcription program. Proceedings of the National Academy of Sciences of the United States of America. 110: E968-77. PMID 23388635 DOI: 10.1073/pnas.1120991110  1
2013 Sigova AA, Mullen AC, Molinie B, Gupta S, Orlando DA, Guenther MG, Almada AE, Lin C, Sharp PA, Giallourakis CC, Young RA. Divergent transcription of long noncoding RNA/mRNA gene pairs in embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 2876-81. PMID 23382218 DOI: 10.1073/pnas.1221904110  1
2013 Simmons Kovacs LA, Mayhew MB, Orlando DA, Jin Y, Li Q, Huang C, Reed SI, Mukherjee S, Haase SB. Errata to Cyclin-dependent kinases are regulators and effectors of oscillations driven by a transcription factor network [Molecular Cell, 45 (2012) 669-679] Molecular Cell. 49: 1177-1179. DOI: 10.1016/j.molcel.2013.03.007  1
2012 Lovén J, Orlando DA, Sigova AA, Lin CY, Rahl PB, Burge CB, Levens DL, Lee TI, Young RA. Revisiting global gene expression analysis. Cell. 151: 476-82. PMID 23101621 DOI: 10.1016/j.cell.2012.10.012  1
2012 Orlando DA, Guenther MG, Frampton GM, Young RA. CpG island structure and trithorax/polycomb chromatin domains in human cells. Genomics. 100: 320-6. PMID 22819920 DOI: 10.1016/j.ygeno.2012.07.006  1
2012 Simmons Kovacs LA, Mayhew MB, Orlando DA, Jin Y, Li Q, Huang C, Reed SI, Mukherjee S, Haase SB. Cyclin-dependent kinases are regulators and effectors of oscillations driven by a transcription factor network. Molecular Cell. 45: 669-79. PMID 22306294 DOI: 10.1016/j.molcel.2011.12.033  1
2012 Whyte WA, Bilodeau S, Orlando DA, Hoke HA, Frampton GM, Foster CT, Cowley SM, Young RA. Enhancer decommissioning by LSD1 during embryonic stem cell differentiation. Nature. 482: 221-5. PMID 22297846 DOI: 10.1038/nature10805  1
2011 Mullen AC, Orlando DA, Newman JJ, Lovén J, Kumar RM, Bilodeau S, Reddy J, Guenther MG, DeKoter RP, Young RA. Master transcription factors determine cell-type-specific responses to TGF-β signaling. Cell. 147: 565-76. PMID 22036565 DOI: 10.1016/j.cell.2011.08.050  1
2011 Ceol CJ, Houvras Y, Jane-Valbuena J, Bilodeau S, Orlando DA, Battisti V, Fritsch L, Lin WM, Hollmann TJ, Ferré F, Bourque C, Burke CJ, Turner L, Uong A, Johnson LA, et al. The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset. Nature. 471: 513-7. PMID 21430779 DOI: 10.1038/nature09806  1
2011 Kagey MH, Newman JJ, Bilodeau S, Zhan Y, Orlando DA, Van Berkum NL, Ebmeier CC, Goossens J, Rahl PB, Levine SS, Taatjes DJ, Dekker J, Young RA. Mediator and cohesin connect gene expression and chromatin architecture (Nature (2010) 467 (430-435)) Nature. 472: 247. DOI: 10.1038/nature09930  1
2010 Kagey MH, Newman JJ, Bilodeau S, Zhan Y, Orlando DA, van Berkum NL, Ebmeier CC, Goossens J, Rahl PB, Levine SS, Taatjes DJ, Dekker J, Young RA. Mediator and cohesin connect gene expression and chromatin architecture. Nature. 467: 430-5. PMID 20720539 DOI: 10.1038/nature09380  1
2009 Orlando DA, Iversen ES, Hartemink AJ, Haase SB. A branching process model for flow cytometry and budding index measurements in cell synchrony experiments. The Annals of Applied Statistics. 3: 1521-1541. PMID 21853014 DOI: 10.1214/09-AOAS264  1
2009 Crutchley J, King KM, Keaton MA, Szkotnicki L, Orlando DA, Zyla TR, Bardes ES, Lew DJ. Molecular dissection of the checkpoint kinase Hsl1p. Molecular Biology of the Cell. 20: 1926-36. PMID 19211841 DOI: 10.1091/mbc.E08-08-0848  1
2008 Simmons Kovacs LA, Orlando DA, Haase SB. Transcription networks and cyclin/CDKs: the yin and yang of cell cycle oscillators. Cell Cycle (Georgetown, Tex.). 7: 2626-9. PMID 18758238  1
2008 Chaudhuri B, Hörmann F, Lalonde S, Brady SM, Orlando DA, Benfey P, Frommer WB. Protonophore- and pH-insensitive glucose and sucrose accumulation detected by FRET nanosensors in Arabidopsis root tips. The Plant Journal : For Cell and Molecular Biology. 56: 948-62. PMID 18702670 DOI: 10.1111/j.1365-313X.2008.03652.x  1
2008 Orlando DA, Lin CY, Bernard A, Wang JY, Socolar JE, Iversen ES, Hartemink AJ, Haase SB. Global control of cell-cycle transcription by coupled CDK and network oscillators. Nature. 453: 944-7. PMID 18463633 DOI: 10.1038/nature06955  1
2007 Orlando DA, Lin CY, Bernard A, Iversen ES, Hartemink AJ, Haase SB. A probabilistic model for cell cycle distributions in synchrony experiments. Cell Cycle (Georgetown, Tex.). 6: 478-88. PMID 17329975  1
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