Year |
Citation |
Score |
2020 |
Gao X, Li R, Cahan P, Zhao Y, Yourick JJ, Sprando RL. Hepatocyte-like cells derived from human induced pluripotent stem cells using small molecules: implications of a transcriptomic study. Stem Cell Research & Therapy. 11: 393. PMID 32917265 DOI: 10.1186/S13287-020-01914-1 |
0.405 |
|
2020 |
Bian Q, Cheng YH, Wilson JP, Su EY, Kim DW, Wang H, Yoo S, Blackshaw S, Cahan P. A single cell transcriptional atlas of early synovial joint development. Development (Cambridge, England). PMID 32580935 DOI: 10.1242/Dev.185777 |
0.352 |
|
2020 |
Nagpal N, Wang J, Zeng J, Lo E, Moon DH, Luk K, Braun RO, Burroughs LM, Keel SB, Reilly C, Lindsley RC, Wolfe SA, Tai AK, Cahan P, Bauer DE, et al. Small-Molecule PAPD5 Inhibitors Restore Telomerase Activity in Patient Stem Cells. Cell Stem Cell. PMID 32320679 DOI: 10.1016/J.Stem.2020.03.016 |
0.395 |
|
2020 |
Chen MJ, Lummertz da Rocha E, Cahan P, Kubaczka C, Hunter P, Sousa P, Mullin NK, Fujiwara Y, Nguyen M, Tan Y, Landry S, Han A, Yang S, Lu YF, Jha DK, et al. Transcriptome Dynamics of Hematopoietic Stem Cell Formation Revealed Using a Combinatorial Runx1 and Ly6a Reporter System. Stem Cell Reports. PMID 32302558 DOI: 10.1016/J.Stemcr.2020.03.020 |
0.444 |
|
2019 |
Sommerfeld SD, Cherry C, Schwab RM, Chung L, Maestas DR, Laffont P, Stein JE, Tam A, Ganguly S, Housseau F, Taube JM, Pardoll DM, Cahan P, Elisseeff JH. Interleukin-36γ-producing macrophages drive IL-17-mediated fibrosis. Science Immunology. 4. PMID 31604843 DOI: 10.1126/Sciimmunol.Aax4783 |
0.321 |
|
2019 |
Tan Y, Cahan P. SingleCellNet: A Computational Tool to Classify Single Cell RNA-Seq Data Across Platforms and Across Species. Cell Systems. PMID 31377170 DOI: 10.1016/J.Cels.2019.06.004 |
0.381 |
|
2019 |
Kinney MA, Vo LT, Frame JM, Barragan J, Conway AJ, Li S, Wong KK, Collins JJ, Cahan P, North TE, Lauffenburger DA, Daley GQ. A systems biology pipeline identifies regulatory networks for stem cell engineering. Nature Biotechnology. 37: 810-818. PMID 31267104 DOI: 10.1038/S41587-019-0159-2 |
0.424 |
|
2019 |
Ahmed R, Omidian Z, Giwa A, Cornwell B, Majety N, Bell DR, Lee S, Zhang H, Michels A, Desiderio S, Sadegh-Nasseri S, Rabb H, Gritsch S, Suva ML, Cahan P, et al. A Public BCR Present in a Unique Dual-Receptor-Expressing Lymphocyte from Type 1 Diabetes Patients Encodes a Potent T Cell Autoantigen. Cell. 177: 1583-1599.e16. PMID 31150624 DOI: 10.1016/J.Cell.2019.05.007 |
0.381 |
|
2019 |
Lo EKW, Cahan P. Cell Fate Engineering Tools for iPSC Disease Modeling. Methods in Molecular Biology (Clifton, N.J.). 1975: 427-454. PMID 31062321 DOI: 10.1007/978-1-4939-9224-9_19 |
0.393 |
|
2018 |
Spangler A, Su EY, Craft AM, Cahan P. A single cell transcriptional portrait of embryoid body differentiation and comparison to progenitors of the developing embryo. Stem Cell Research. 31: 201-215. PMID 30118958 DOI: 10.1016/J.Scr.2018.07.022 |
0.387 |
|
2018 |
Cesana M, Guo MH, Cacchiarelli D, Wahlster L, Barragan J, Doulatov S, Vo LT, Salvatori B, Trapnell C, Clement K, Cahan P, Tsanov KM, Sousa PM, Tazon-Vega B, Bolondi A, et al. A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development. Cell Stem Cell. 22: 575-588.e7. PMID 29625070 DOI: 10.1016/J.Stem.2018.03.012 |
0.371 |
|
2018 |
Nagpal N, Wang J, Lo E, Tai A, Cahan P, Fong Y, Agarwal S. Therapeutic Targeting of Telomere Diseases Via Novel Small Molecule Modulators of Non-Coding RNA Biogenesis Blood. 132: 647-647. DOI: 10.1182/Blood-2018-99-118800 |
0.38 |
|
2017 |
Velazquez JJ, Su E, Cahan P, Ebrahimkhani MR. Programming Morphogenesis through Systems and Synthetic Biology. Trends in Biotechnology. PMID 29229492 DOI: 10.1016/J.Tibtech.2017.11.003 |
0.414 |
|
2017 |
Radley AH, Schwab RM, Tan Y, Kim J, Lo EKW, Cahan P. Assessment of engineered cells using CellNet and RNA-seq. Nature Protocols. 12: 1089-1102. PMID 28448485 DOI: 10.1038/Nprot.2017.022 |
0.439 |
|
2017 |
Kumar P, Tan Y, Cahan P. Understanding development and stem cells using single cell-based analyses of gene expression. Development (Cambridge, England). 144: 17-32. PMID 28049689 DOI: 10.1242/Dev.133058 |
0.482 |
|
2016 |
Lu YF, Cahan P, Ross S, Sahalie J, Sousa PM, Hadland BK, Cai W, Serrao E, Engelman AN, Bernstein ID, Daley GQ. Engineered Murine HSCs Reconstitute Multi-lineage Hematopoiesis and Adaptive Immunity. Cell Reports. 17: 3178-3192. PMID 28009288 DOI: 10.1016/J.Celrep.2016.11.077 |
0.407 |
|
2016 |
Boyraz B, Moon DH, Segal M, Muosieyiri MZ, Aykanat A, Tai AK, Cahan P, Agarwal S. Posttranscriptional manipulation of TERC reverses molecular hallmarks of telomere disease. The Journal of Clinical Investigation. PMID 27482890 DOI: 10.1172/Jci87547 |
0.339 |
|
2016 |
Powers JT, Tsanov KM, Pearson DS, Roels F, Spina CS, Ebright R, Seligson M, de Soysa Y, Cahan P, Theißen J, Tu HC, Han A, Kurek KC, LaPier GS, Osborne JK, et al. Multiple mechanisms disrupt the let-7 microRNA family in neuroblastoma. Nature. PMID 27383785 DOI: 10.1038/Nature18632 |
0.341 |
|
2016 |
Zhang J, Ratanasirintrawoot S, Chandrasekaran S, Wu Z, Ficarro SB, Yu C, Ross CA, Cacchiarelli D, Xia Q, Seligson M, Shinoda G, Xie W, Cahan P, Wang L, Ng SC, et al. LIN28 Regulates Stem Cell Metabolism and Conversion to Primed Pluripotency. Cell Stem Cell. PMID 27320042 DOI: 10.1016/J.Stem.2016.05.009 |
0.364 |
|
2016 |
Bian Q, Cahan P. Computational Tools for Stem Cell Biology. Trends in Biotechnology. PMID 27318512 DOI: 10.1016/J.Tibtech.2016.05.010 |
0.379 |
|
2016 |
Cahan P. Enabling direct fate conversion with network biology. Nature Genetics. 48: 226-7. PMID 26906680 DOI: 10.1038/Ng.3516 |
0.337 |
|
2016 |
Powers JT, Tsanov K, Roels F, Spina C, Ebright R, Seligson M, Soysa Yd, Cahan P, Pearson D, Theißen J, Tu H, LaPier G, Osborne J, Ross S, Collins J, et al. Abstract LB-165: Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-165 |
0.386 |
|
2015 |
Uosaki H, Cahan P, Lee DI, Wang S, Miyamoto M, Fernandez L, Kass DA, Kwon C. Transcriptional Landscape of Cardiomyocyte Maturation. Cell Reports. PMID 26586429 DOI: 10.1016/J.Celrep.2015.10.032 |
0.361 |
|
2015 |
Moon DH, Segal M, Boyraz B, Guinan E, Hofmann I, Cahan P, Tai AK, Agarwal S. Poly(A)-specific ribonuclease (PARN) mediates 3'-end maturation of the telomerase RNA component. Nature Genetics. PMID 26482878 DOI: 10.1038/Ng.3423 |
0.378 |
|
2015 |
Moon DH, Segal M, Boyraz B, Guinan E, Hofmann I, Cahan P, Tai AK, Agarwal S. Mutations in the Poly(A)-Specific Ribonuclease (PARN) Impair Telomerase RNA 3' End Maturation in Dyskeratosis Congenita Patients Blood. 126: 669-669. DOI: 10.1182/Blood.V126.23.669.669 |
0.373 |
|
2015 |
Powers JT, Tsanov KM, Roles F, Ebright R, Seligson M, Soysa Yd, Cahan P, Theissen J, LaPier GS, Pearson DS, Berthold F, Daley GQ. Abstract LB-290: Multiple distinct mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-290 |
0.388 |
|
2015 |
Kumar RM, Cahan P, Shalek AK, Satija R, DaleyKeyser AJ, Li H, Zhang J, Pardee K, Gennert D, Trombetta JJ, Ferrante TC, Regev A, Daley GQ, Collins JJ. Erratum: Deconstructing transcriptional heterogeneity in pluripotent stem cells Nature. 519: 118-118. DOI: 10.1038/Nature14150 |
0.305 |
|
2014 |
Kumar RM, Cahan P, Shalek AK, Satija R, DaleyKeyser AJ, Li H, Zhang J, Pardee K, Gennert D, Trombetta JJ, Ferrante TC, Regev A, Daley GQ, Collins JJ. Deconstructing transcriptional heterogeneity in pluripotent stem cells. Nature. 516: 56-61. PMID 25471879 DOI: 10.1038/Nature13920 |
0.403 |
|
2014 |
Zhao R, Deibler RW, Lerou PH, Ballabeni A, Heffner GC, Cahan P, Unternaehrer JJ, Kirschner MW, Daley GQ. A nontranscriptional role for Oct4 in the regulation of mitotic entry. Proceedings of the National Academy of Sciences of the United States of America. 111: 15768-73. PMID 25324523 DOI: 10.1073/Pnas.1417518111 |
0.39 |
|
2014 |
Cahan P, Li H, Morris SA, Lummertz da Rocha E, Daley GQ, Collins JJ. CellNet: network biology applied to stem cell engineering. Cell. 158: 903-15. PMID 25126793 DOI: 10.1016/J.Cell.2014.07.020 |
0.41 |
|
2014 |
Morris SA, Cahan P, Li H, Zhao AM, San Roman AK, Shivdasani RA, Collins JJ, Daley GQ. Dissecting engineered cell types and enhancing cell fate conversion via CellNet. Cell. 158: 889-902. PMID 25126792 DOI: 10.1016/J.Cell.2014.07.021 |
0.378 |
|
2014 |
Yimlamai D, Christodoulou C, Galli GG, Yanger K, Pepe-Mooney B, Gurung B, Shrestha K, Cahan P, Stanger BZ, Camargo FD. Hippo pathway activity influences liver cell fate. Cell. 157: 1324-38. PMID 24906150 DOI: 10.1016/J.Cell.2014.03.060 |
0.358 |
|
2013 |
Cahan P, Daley GQ. Origins and implications of pluripotent stem cell variability and heterogeneity. Nature Reviews. Molecular Cell Biology. 14: 357-68. PMID 23673969 DOI: 10.1038/Nrm3584 |
0.419 |
|
2012 |
McKinney-Freeman S, Cahan P, Li H, Lacadie SA, Huang HT, Curran M, Loewer S, Naveiras O, Kathrein KL, Konantz M, Langdon EM, Lengerke C, Zon LI, Collins JJ, Daley GQ. The transcriptional landscape of hematopoietic stem cell ontogeny. Cell Stem Cell. 11: 701-14. PMID 23122293 DOI: 10.1016/J.Stem.2012.07.018 |
0.421 |
|
2012 |
Onder TT, Kara N, Cherry A, Sinha AU, Zhu N, Bernt KM, Cahan P, Marcarci BO, Unternaehrer J, Gupta PB, Lander ES, Armstrong SA, Daley GQ. Chromatin-modifying enzymes as modulators of reprogramming. Nature. 483: 598-602. PMID 22388813 DOI: 10.1038/Nature10953 |
0.363 |
|
2012 |
Kim K, Zhao R, Doi A, Ng K, Unternaehrer J, Cahan P, Hongguang H, Loh YH, Aryee MJ, Lensch MW, Li H, Collins JJ, Feinberg AP, Daley GQ. Erratum: Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells (Nature Biotechnology (2011) 29 (1117-1119)) Nature Biotechnology. 30. DOI: 10.1038/Nbt0112-112B |
0.393 |
|
2011 |
Kim K, Zhao R, Doi A, Ng K, Unternaehrer J, Cahan P, Huo H, Loh YH, Aryee MJ, Lensch MW, Li H, Collins JJ, Feinberg AP, Daley GQ. Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells. Nature Biotechnology. 29: 1117-9. PMID 22119740 DOI: 10.1038/Nbt.2052 |
0.387 |
|
2011 |
Wartman LD, Larson DE, Xiang Z, Ding L, Chen K, Lin L, Cahan P, Klco JM, Welch JS, Li C, Payton JE, Uy GL, Varghese N, Ries RE, Hoock M, et al. Sequencing a mouse acute promyelocytic leukemia genome reveals genetic events relevant for disease progression. The Journal of Clinical Investigation. 121: 1445-55. PMID 21436584 DOI: 10.1172/Jci45284 |
0.665 |
|
2011 |
Zhu H, Lensch MW, Cahan P, Daley GQ. Investigating monogenic and complex diseases with pluripotent stem cells. Nature Reviews. Genetics. 12: 266-75. PMID 21386866 DOI: 10.1038/Nrg2951 |
0.434 |
|
2010 |
Cahan P, Graubert TA. Integrated genomics of susceptibility to alkylator-induced leukemia in mice. Bmc Genomics. 11: 638. PMID 21080971 DOI: 10.1186/1471-2164-11-638 |
0.634 |
|
2010 |
Higuchi DA, Cahan P, Gao J, Ferris ST, Poursine-Laurent J, Graubert TA, Yokoyama WM. Structural variation of the mouse natural killer gene complex. Genes and Immunity. 11: 637-48. PMID 20861859 DOI: 10.1038/Gene.2010.48 |
0.614 |
|
2010 |
Kim K, Doi A, Wen B, Ng K, Zhao R, Cahan P, Kim J, Aryee MJ, Ji H, Ehrlich LI, Yabuuchi A, Takeuchi A, Cunniff KC, Hongguang H, McKinney-Freeman S, et al. Epigenetic memory in induced pluripotent stem cells. Nature. 467: 285-90. PMID 20644535 DOI: 10.1038/Nature09342 |
0.405 |
|
2010 |
Fortier JM, Payton JE, Cahan P, Ley TJ, Walter MJ, Graubert TA. POU4F1 is associated with t(8;21) acute myeloid leukemia and contributes directly to its unique transcriptional signature. Leukemia. 24: 950-7. PMID 20376082 DOI: 10.1038/Leu.2010.61 |
0.698 |
|
2009 |
Cahan P, Li Y, Izumi M, Graubert TA. The impact of copy number variation on local gene expression in mouse hematopoietic stem and progenitor cells. Nature Genetics. 41: 430-7. PMID 19270704 DOI: 10.1038/Ng.350 |
0.66 |
|
2009 |
Fortier JM, Payton JE, Cahan P, Ley TJ, Walter MJ, Graubert TA. POU4F1 Is Associated with t(8;21) AML and Contributes Directly to Its Unique Transcriptional Signature. Blood. 114: 2623-2623. DOI: 10.1182/Blood.V114.22.2623.2623 |
0.714 |
|
2009 |
Li Y, Cahan P, Izumi M, Graubert T. Caspase-9: A Candidate Susceptibility Factor for Murine Alkylator-Induced Leukemia. Blood. 114: 1273-1273. DOI: 10.1182/Blood.V114.22.1273.1273 |
0.685 |
|
2008 |
Cahan P, Godfrey LE, Eis PS, Richmond TA, Selzer RR, Brent M, McLeod HL, Ley TJ, Graubert TA. wuHMM: a robust algorithm to detect DNA copy number variation using long oligonucleotide microarray data. Nucleic Acids Research. 36: e41. PMID 18334530 DOI: 10.1093/Nar/Gkn110 |
0.619 |
|
2008 |
Janke MR, Babatunde F, Cahan P, Cheverud JM, Graubert TA. MLF1 Is a Candidate Susceptibility Factor for T-AML That Induces Apoptosis in Normal Hematopoietic Cells Blood. 112: 310-310. DOI: 10.1182/Blood.V112.11.310.310 |
0.713 |
|
2008 |
Funk R, Cahan P, Izumi M, Graubert T. Bcl2, a Candidate Murine Therapy-Related Acute Myeloid Leukemia Susceptibility Factor, Exhibits Strain-Dependent and Alkylator-Responsive Expression. Blood. 112: 1499-1499. DOI: 10.1182/Blood.V112.11.1499.1499 |
0.608 |
|
2007 |
Cahan P, Rovegno F, Mooney D, Newman JC, St Laurent G, McCaffrey TA. Meta-analysis of microarray results: challenges, opportunities, and recommendations for standardization. Gene. 401: 12-8. PMID 17651921 DOI: 10.1016/J.Gene.2007.06.016 |
0.353 |
|
2007 |
Graubert TA, Cahan P, Edwin D, Selzer RR, Richmond TA, Eis PS, Shannon WD, Li X, McLeod HL, Cheverud JM, Ley TJ. A high-resolution map of segmental DNA copy number variation in the mouse genome. Plos Genetics. 3: e3. PMID 17206864 DOI: 10.1371/Journal.Pgen.0030003 |
0.67 |
|
2006 |
de la Fuente C, Gupta MV, Klase Z, Strouss K, Cahan P, McCaffery T, Galante A, Soteropoulos P, Pumfery A, Fujii M, Kashanchi F. Involvement of HTLV-I Tax and CREB in aneuploidy: a bioinformatics approach. Retrovirology. 3: 43. PMID 16822311 DOI: 10.1186/1742-4690-3-43 |
0.397 |
|
2006 |
Cahan P, Marsh S, McLeod HL. Systems pharmacogenomics in yeast. Pharmacogenomics. 7: 255-9. PMID 16515406 DOI: 10.2217/14622416.7.2.255 |
0.301 |
|
2005 |
Cahan P, Ahmad AM, Burke H, Fu S, Lai Y, Florea L, Dharker N, Kobrinski T, Kale P, McCaffrey TA. List of lists-annotated (LOLA): a database for annotation and comparison of published microarray gene lists. Gene. 360: 78-82. PMID 16140476 DOI: 10.1016/J.Gene.2005.07.008 |
0.404 |
|
2005 |
Gagarin D, Yang Z, Butler J, Wimmer M, Du B, Cahan P, McCaffrey TA. Genomic profiling of acquired resistance to apoptosis in cells derived from human atherosclerotic lesions: potential role of STATs, cyclinD1, BAD, and Bcl-XL. Journal of Molecular and Cellular Cardiology. 39: 453-65. PMID 16005468 DOI: 10.1016/J.Yjmcc.2005.01.015 |
0.348 |
|
Show low-probability matches. |