Aaron R. Thorner, Ph.D. - Publications

Affiliations: 
2010 Genetics & Molecular Biology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Bioinformatics, Genetics, Oncology

73 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Bekele RT, Samant AS, Nassar AH, So J, Garcia EP, Curran CR, Hwang JH, Mayhew DL, Nag A, Thorner AR, Börcsök J, Sztupinszki Z, Pan CX, Bellmunt J, Kwiatkowski DJ, et al. RAF1 amplification drives a subset of bladder tumors and confers sensitivity to MAPK-directed therapeutics. The Journal of Clinical Investigation. PMID 34554931 DOI: 10.1172/JCI147849  0.327
2021 Chung TKH, Doran G, Cheung TH, Yim SF, Yu MY, Worley MJ, Elias KM, Thorner AR, Pedamallu CS, Ojesina AI, Lau KM, Ducar MD, Wong RRY, Wang VW, Nag A, et al. Dissection of Aberration for Cervical Adenocarcinoma Outcomes. Cancers. 13. PMID 34203201 DOI: 10.3390/cancers13133218  0.323
2020 Enache OM, Rendo V, Abdusamad M, Lam D, Davison D, Pal S, Currimjee N, Hess J, Pantel S, Nag A, Thorner AR, Doench JG, Vazquez F, Beroukhim R, Golub TR, et al. Cas9 activates the p53 pathway and selects for p53-inactivating mutations. Nature Genetics. PMID 32424350 DOI: 10.1038/S41588-020-0623-4  0.377
2020 Ge JY, Shu S, Kwon M, Jovanović B, Murphy K, Gulvady A, Fassl A, Trinh A, Kuang Y, Heavey GA, Luoma A, Paweletz C, Thorner AR, Wucherpfennig KW, Qi J, et al. Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer. Nature Communications. 11: 2350. PMID 32393766 DOI: 10.1038/S41467-020-16170-3  0.34
2020 Lasseter K, Nassar AH, Hamieh L, Berchuck JE, Nuzzo PV, Korthauer K, Shinagare AB, Ogorek B, McKay R, Thorner AR, Lee GM, Braun DA, Bhatt RS, Freedman M, Choueiri TK, et al. Plasma cell-free DNA variant analysis compared with methylated DNA analysis in renal cell carcinoma. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 32341571 DOI: 10.1038/S41436-020-0801-X  0.334
2020 Starrett GJ, Thakuria M, Chen T, Marcelus C, Cheng J, Nomburg J, Thorner AR, Slevin MK, Powers W, Burns RT, Perry C, Piris A, Kuo FC, Rabinowits G, Giobbie-Hurder A, et al. Clinical and molecular characterization of virus-positive and virus-negative Merkel cell carcinoma. Genome Medicine. 12: 30. PMID 32188490 DOI: 10.1186/S13073-020-00727-4  0.337
2020 Slevin MK, Wollison BM, Powers W, Burns RT, Patel N, Ducar MD, Starrett GJ, Garcia EP, Manning DK, Cheng J, Hanna GJ, Kaye KM, Van Hummelen P, Nag A, Thorner AR, et al. ViroPanel: Hybrid capture and massively parallel sequencing for simultaneous detection and profiling of oncogenic virus infection and tumor genome. The Journal of Molecular Diagnostics : Jmd. PMID 32068070 DOI: 10.1016/J.Jmoldx.2019.12.010  0.377
2019 Wienand K, Chapuy B, Stewart C, Dunford AJ, Wu D, Kim J, Kamburov A, Wood TR, Cader FZ, Ducar MD, Thorner AR, Nag A, Heubeck AT, Buonopane MJ, Redd RA, et al. Genomic analyses of flow-sorted Hodgkin Reed-Sternberg cells reveal complementary mechanisms of immune evasion. Blood Advances. 3: 4065-4080. PMID 31816062 DOI: 10.1182/Bloodadvances.2019001012  0.432
2019 Chapuy B, Stewart C, Dunford AJ, Kim J, Wienand K, Kamburov A, Griffin GK, Chen PH, Lako A, Redd R, Cote CM, Ducar MD, Thorner AR, Rodig SJ, Getz G, et al. Genomic Analyses of PMBL Reveal New Drivers and Mechanisms of Sensitivity to PD-1 Blockade. Blood. PMID 31697821 DOI: 10.1182/Blood.2019002067  0.39
2019 Nassar AH, Hamieh L, Gray KP, Thorner AR, Fay AP, Lasseter KD, Abou Alaiwi S, Nuzzo PV, Flippot R, Krajewski KM, Signoretti S, Choueiri TK, Kwiatkowski DJ. Mutations and Response to Rapalogs in Patients with Metastatic Renal Cell Carcinoma. Molecular Cancer Therapeutics. PMID 31653662 DOI: 10.1158/1535-7163.Mct-19-0642  0.411
2019 Corso S, Isella C, Bellomo SE, Apicella M, Durando S, Migliore C, Ughetto S, D'Errico L, Menegon S, Moya-Rull D, Cargnelutti M, Capeloa T, Conticelli D, Giordano J, Venesio T, ... ... Thorner AR, et al. A comprehensive PDX gastric cancer collection captures cancer cell intrinsic transcriptional MSI traits. Cancer Research. PMID 31585941 DOI: 10.1158/0008-5472.Can-19-1166  0.399
2019 Jan M, Leventhal MJ, Morgan EA, Wengrod JC, Nag A, Drinan SD, Wollison BM, Ducar MD, Thorner AR, Leppanen S, Baronas J, Stevens J, Lane WJ, Kekre N, Ho VT, et al. Recurrent genetic HLA loss in AML relapsed after matched unrelated allogeneic hematopoietic cell transplantation. Blood Advances. 3: 2199-2204. PMID 31324640 DOI: 10.1182/Bloodadvances.2019000445  0.328
2019 Hamieh L, Nassar A, Lasseter K, Ogorek B, McKay RR, Thorner A, Nag A, Lee GM, Bhatt RS, Pomerantz M, Freedman ML, Kwiatkowski DJ, Choueiri TK. Cell-free DNA analysis in renal cell carcinoma: Comparison with tumor sequencing and correlation with response to therapy. Journal of Clinical Oncology. 37: 655-655. DOI: 10.1200/Jco.2019.37.7_Suppl.655  0.435
2019 Wienand K, Chapuy B, Stewart C, Dunford A, Wu D, Kim J, Kamburov A, Wood T, Cader FZ, Ducar MD, Thorner AR, Nag A, Griffin GK, Chen P, Heubeck AT, et al. Comparative Genomic Analyses Defines Shared and Unique Features of cHL and PMBL and New Mechanisms of Sensitivity to PD-1 Blockade Blood. 134: 1493-1493. DOI: 10.1182/Blood-2019-131904  0.402
2019 Knudsen TA, Skov V, Werner L, Duke W, Gibson CJ, Nag A, Thorner AR, Wollison B, Hansen DL, Larsen TS, Ellervik C, El Fassi D, Stricker Kd, Ocias LF, Brabrand M, et al. Genomic Profiling of a Phase III Clinical Trial of Interferon Versus Hydroxyurea in MPN Patients Reveals Mutation-Specific and Treatment-Specific Patterns of Response Blood. 134: 4202-4202. DOI: 10.1182/Blood-2019-126164  0.385
2018 da Silva A, Bowden M, Zhang S, Masugi Y, Thorner AR, Herbert ZT, Zhou CW, Brais L, Chan JA, Hodi FS, Rodig S, Ogino S, Kulke MH. Characterization of the Neuroendocrine Tumor Immune Microenvironment. Pancreas. PMID 30153220 DOI: 10.1097/Mpa.0000000000001150  0.323
2018 Ben-David U, Siranosian B, Ha G, Tang H, Oren Y, Hinohara K, Strathdee CA, Dempster J, Lyons NJ, Burns R, Nag A, Kugener G, Cimini B, Tsvetkov P, Maruvka YE, ... ... Thorner AR, et al. Genetic and transcriptional evolution alters cancer cell line drug response. Nature. PMID 30089904 DOI: 10.1038/S41586-018-0409-3  0.353
2018 Yurgelun MB, Chittenden AB, Morales-Oyarvide V, Rubinson DA, Dunne RF, Kozak MM, Qian ZR, Welch MW, Brais LK, Da Silva A, Bui JL, Yuan C, Li T, Li W, Masuda A, ... ... Thorner AR, et al. Germline cancer susceptibility gene variants, somatic second hits, and survival outcomes in patients with resected pancreatic cancer. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 29961768 DOI: 10.1038/S41436-018-0009-5  0.362
2018 Ng SY, Yoshida N, Christie AL, Ghandi M, Dharia NV, Dempster J, Murakami M, Shigemori K, Morrow SN, Van Scoyk A, Cordero NA, Stevenson KE, Puligandla M, Haas B, Lo C, ... ... Thorner AR, et al. Targetable vulnerabilities in T- and NK-cell lymphomas identified through preclinical models. Nature Communications. 9: 2024. PMID 29789628 DOI: 10.1038/S41467-018-04356-9  0.323
2018 Chapuy B, Stewart C, Dunford AJ, Kim J, Kamburov A, Redd RA, Lawrence MS, Roemer MGM, Li AJ, Ziepert M, Staiger AM, Wala JA, Ducar MD, Leshchiner I, Rheinbay E, ... ... Thorner AR, et al. Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes. Nature Medicine. PMID 29713087 DOI: 10.1038/S41591-018-0016-8  0.381
2018 Burns MA, Liao ZW, Yamagata N, Pouliot GP, Stevenson KE, Neuberg DS, Thorner AR, Ducar M, Silverman EA, Hunger SP, Loh ML, Winter SS, Dunsmore KP, Wood B, Devidas M, et al. Hedgehog pathway mutations drive oncogenic transformation in high-risk T-cell acute lymphoblastic leukemia. Leukemia. PMID 29654263 DOI: 10.1038/S41375-018-0097-X  0.359
2018 Bockorny B, Rusan M, Chen W, Liao RG, Li Y, Piccioni F, Wang J, Tan L, Thorner AR, Li T, Zhang Y, Miao CH, Ovesen T, Shapiro GI, Kwiatkowski DJ, et al. RAS-MAPK reactivation facilitates acquired resistance in FGFR1-amplified lung cancer and underlies a rationale for upfront FGFR-MEK blockade. Molecular Cancer Therapeutics. PMID 29654068 DOI: 10.1158/1535-7163.Mct-17-0464  0.315
2018 Stachler MD, Camarda ND, Deitrick C, Kim A, Agoston AT, Odze RD, Hornick JL, Nag A, Thorner AR, Ducar M, Noffsinger A, Lash RH, Redston M, Carter SL, Davison JM, et al. Detection of Mutations in Barrett's Esophagus Before Progression to High-grade Dysplasia or Adenocarcinoma. Gastroenterology. PMID 29608884 DOI: 10.1053/J.Gastro.2018.03.047  0.359
2018 Melchardt T, Magnes T, Hufnagl C, Thorner AR, Ducar M, Neureiter D, Tränkenschuh W, Klieser E, Gaggl A, Rösch S, Rasp G, Hartmann TN, Pleyer L, Rinnerthaler G, Weiss L, et al. Clonal evolution and heterogeneity in metastatic head and neck cancer-An analysis of the Austrian Study Group of Medical Tumour Therapy study group. European Journal of Cancer (Oxford, England : 1990). 93: 69-78. PMID 29477794 DOI: 10.1016/J.Ejca.2018.01.064  0.322
2018 Teot LA, Schneider M, Thorner AR, Tian J, Chi YY, Ducar M, Lin L, Wlodarski M, Grier HE, Fletcher CDM, van Hummelen P, Skapek SX, Hawkins DS, Wagers AJ, Rodriguez-Galindo C, et al. Clinical and mutational spectrum of highly differentiated, paired box 3:forkhead box protein o1 fusion-negative rhabdomyosarcoma: A report from the Children's Oncology Group. Cancer. PMID 29461635 DOI: 10.1002/Cncr.31286  0.302
2018 MacConaill LE, Burns RT, Nag A, Coleman HA, Slevin MK, Giorda K, Light M, Lai K, Jarosz M, McNeill MS, Ducar MD, Meyerson M, Thorner AR. Unique, dual-indexed sequencing adapters with UMIs effectively eliminate index cross-talk and significantly improve sensitivity of massively parallel sequencing. Bmc Genomics. 19: 30. PMID 29310587 DOI: 10.1186/S12864-017-4428-5  0.319
2018 Hemming ML, Klega KS, Acker KE, Nag A, Thorner A, Nathenson M, Raut CP, Crompton BD, George S. Identification of leiomyosarcoma circulating tumor DNA through ultra-low passage whole genome sequencing and correlation with tumor burden: A pilot experience. Journal of Clinical Oncology. 36: 11565-11565. DOI: 10.1200/Jco.2018.36.15_Suppl.11565  0.409
2018 Wienand K, Chapuy B, Stewart C, Dunford A, Wu D, Kim J, Kamburov A, Cader FZ, Ducar MD, Thorner AR, Heubeck AT, Buonopane MJ, Armand P, Rodig SJ, Fromm JR, et al. Comprehensive Genomic Analysis of Flow-Sorted Hodgkin Reed Sternberg Cells Reveals Additional Genetic Bases of Immune Evasion Blood. 132: 1559-1559. DOI: 10.1182/Blood-2018-99-118453  0.414
2018 Chapuy B, Stewart C, Dunford A, Kim J, Wienand K, Kamburov A, Griffin GK, Cote CM, Ducar MD, Thorner AR, Rodig SJ, Getz G, Shipp MA. Comprehensive Genomic Analysis of Primary Mediastinal B-Cell Lymphoma Blood. 132: 1564-1564. DOI: 10.1182/Blood-2018-99-118135  0.433
2018 Ben-David U, Siranosian B, Ha G, Tang H, Lyons NJ, Burns R, Nag A, Cimini B, Tsvetkov P, Tubelli AA, Wong B, Thorner AR, Bittker J, Meyerson M, Beroukhim R, et al. Abstract 214: Genetic and transcriptional instability alters cell line drug response Cancer Research. 78: 214-214. DOI: 10.1158/1538-7445.Am2018-214  0.371
2017 Wollison BM, Thai E, Mckinney A, Ward A, Clapp A, Clinton C, Nag A, Thorner AR, Gastier-Foster JM, Crompton BD. Blood collection in cell-stabilizing tubes does not impact germline DNA quality for pediatric patients. Plos One. 12: e0188835. PMID 29206863 DOI: 10.1371/Journal.Pone.0188835  0.335
2017 Pectasides E, Stachler MD, Derks S, Liu Y, Maron S, Islam M, Alpert L, Kwak H, Kindler H, Polite B, Sharma MR, Allen K, O'Day E, Lomnicki S, Maranto M, ... ... Thorner AR, et al. Genomic Heterogeneity as a Barrier to Precision Medicine in Gastroesophageal Adenocarcinoma. Cancer Discovery. PMID 28978556 DOI: 10.1158/2159-8290.Cd-17-0395  0.39
2017 Bi WL, Greenwald NF, Abedalthagafi M, Wala J, Gibson WJ, Agarwalla PK, Horowitz P, Schumacher SE, Esaulova E, Mei Y, Chevalier A, Ducar M, Thorner AR, van Hummelen P, Stemmer-Rachamimov A, et al. Genomic landscape of high-grade meningiomas. Npj Genomic Medicine. 2. PMID 28713588 DOI: 10.1038/S41525-017-0014-7  0.415
2017 Thorner AR, Slevin MK, Clapp A, Coleman HA, McShane SR, Drinan SD, Thai E, Wollison BM, Burns RT, Frieden A, Ducar MD, Nag A, MacConaill LE, Meyerson ML. Abstract 5695: Increased sensitivity for detection of oncogenic mutations present in circulating cell-free tumor DNA Cancer Research. 77: 5695-5695. DOI: 10.1158/1538-7445.Am2017-5695  0.4
2017 Burns RT, Hunter SS, Ducar MD, Thorner AR, Decaprio JA, Hummelen PV, Frieden A, Nag A, Coleman HA, Slevin MK, Clapp A, Drinan SD, McShane SR, Thai E, Shivdasani P, et al. Abstract 562: Oncovirus detection and integration analysis from human tumor samples using targeted massively parallel sequencing Cancer Research. 77: 562-562. DOI: 10.1158/1538-7445.Am2017-562  0.338
2016 Shankar GM, Abedalthagafi M, Vaubel RA, Merrill PH, Nayyar N, Gill CM, Brewster R, Bi WL, Agarwalla PK, Thorner AR, Reardon DA, Al-Mefty O, Wen PY, Alexander BM, van Hummelen P, et al. Germline and somatic BAP1 mutations in high-grade rhabdoid meningiomas. Neuro-Oncology. PMID 28170043 DOI: 10.1093/Neuonc/Now235  0.443
2016 Sholl LM, Do K, Shivdasani P, Cerami E, Dubuc AM, Kuo FC, Garcia EP, Jia Y, Davineni P, Abo RP, Pugh TJ, van Hummelen P, Thorner AR, Ducar M, Berger AH, et al. Institutional implementation of clinical tumor profiling on an unselected cancer population. Jci Insight. 1: e87062. PMID 27882345 DOI: 10.1172/Jci.Insight.87062  0.409
2016 Kwiatkowski DJ, Choueiri TK, Fay AP, Rini BI, Thorner AR, De Velasco G, Tyburczy M, Hamieh L, Albiges L, Agarwal N, Ho TH, Song J, Pignon JC, Barrios PM, Michaelson MD, et al. Mutations in TSC1, TSC2, and MTOR are associated with response to rapalogs in patients with metastatic Renal Cell Carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26831717 DOI: 10.1158/1078-0432.Ccr-15-2631  0.328
2016 Abedalthagafi M, Bi WL, Aizer AA, Merrill PH, Brewster R, Agarwalla PK, Listewnik ML, Dias-Santagata D, Thorner AR, Van Hummelen P, Brastianos PK, Reardon DA, Wen PY, Al-Mefty O, Ramkissoon SH, et al. Oncogenic PI3K mutations are as common as AKT1 and SMO mutations in meningioma. Neuro-Oncology. PMID 26826201 DOI: 10.1093/Neuonc/Nov316  0.387
2016 Chapuy B, Cheng H, Watahiki A, Ducar MD, Tan Y, Chen L, Roemer MG, Ouyang J, Christie AL, Zhang L, Gusenleitner D, Abo RP, Farinha P, von Bonin F, Thorner AR, et al. Diffuse large B-cell lymphoma patient-derived xenograft models capture the molecular and biologic heterogeneity of the disease. Blood. PMID 26773040 DOI: 10.1182/Blood-2015-09-672352  0.422
2016 Huynh MA, Maire CL, Abazeed M, Lam FC, Adams D, Pelton K, Pinnell N, Knoff DC, Korideck H, Hummelen PV, Thorner A, Wen PY, Ligon A, Floyd SR, Schreiber SL, et al. Functional profiling of a glioblastoma (GBM) patient-derived cell line (PDCL) panel to identify cell-intrinsic differential radiation response. Journal of Clinical Oncology. 34: 2069-2069. DOI: 10.1200/Jco.2016.34.15_Suppl.2069  0.345
2016 Thorner AR, Ziaugra L, Ducar MD, Lin L, Laing A, Coleman HA, McShane SR, Clapp A, Paquette RR, Wollison BM, Hoeftberger J, Patel NA, Hunter SS, Manam MD, MacConaill LE, et al. Abstract 3644: Optimization of library construction for massively parallel sequencing using low-input, FFPE-derived DNA without additional PCR amplification Cancer Research. 76: 3644-3644. DOI: 10.1158/1538-7445.Am2016-3644  0.343
2015 Chapuy B, Roemer MG, Stewart C, Tan Y, Abo RP, Zhang L, Dunford AJ, Meredith DM, Thorner AR, Jordanova ES, Liu G, Feuerhake F, Ducar MD, Illerhaus G, Gusenleitner D, et al. Targetable genetic features of primary testicular and primary central nervous system lymphomas. Blood. PMID 26702065 DOI: 10.1182/Blood-2015-10-673236  0.397
2015 Tyburczy ME, Dies KA, Glass J, Camposano S, Chekaluk Y, Thorner AR, Lin L, Krueger D, Franz DN, Thiele EA, Sahin M, Kwiatkowski DJ. Mosaic and Intronic Mutations in TSC1/TSC2 Explain the Majority of TSC Patients with No Mutation Identified by Conventional Testing. Plos Genetics. 11: e1005637. PMID 26540169 DOI: 10.1371/Journal.Pgen.1005637  0.402
2015 Shankar GM, Lelic N, Gill CM, Thorner AR, Van Hummelen P, Wisoff JH, Loeffler JS, Brastianos PK, Shin JH, Borges LF, Butler WE, Zagzag D, Brody RI, Duhaime AC, Taylor MD, et al. BRAF alteration status and the histone H3F3A gene K27M mutation segregate spinal cord astrocytoma histology. Acta Neuropathologica. PMID 26487540 DOI: 10.1007/S00401-015-1492-2  0.369
2015 Brastianos PK, Carter SL, Santagata S, Cahill DP, Taylor-Weiner A, Jones RT, Van Allen EM, Lawrence MS, Horowitz PM, Cibulskis K, Ligon KL, Tabernero J, Seoane J, Martinez-Saez E, Curry WT, ... ... Thorner AR, et al. Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets. Cancer Discovery. PMID 26410082 DOI: 10.1158/2159-8290.Cd-15-0369  0.329
2015 Chung TK, Van Hummelen P, Chan PK, Cheung TH, Yim SF, Yu MY, Ducar MD, Thorner AR, MacConaill LE, Doran G, Pedamallu CS, Ojesina AI, Wong RR, Wang VW, Freeman SS, et al. Genomic aberrations in cervical adenocarcinomas in Hong Kong Chinese women. International Journal of Cancer. Journal International Du Cancer. 137: 776-83. PMID 25626421 DOI: 10.1002/Ijc.29456  0.303
2015 Abo RP, Ducar M, Garcia EP, Thorner AR, Rojas-Rudilla V, Lin L, Sholl LM, Hahn WC, Meyerson M, Lindeman NI, Van Hummelen P, MacConaill LE. BreaKmer: detection of structural variation in targeted massively parallel sequencing data using kmers. Nucleic Acids Research. 43: e19. PMID 25428359 DOI: 10.1093/Nar/Gku1211  0.395
2015 Bellmunt J, Guo G, Mullane SA, Orsola A, Werner L, Van Hummelen P, Thorner A, Loda M, Choueiri TK, Barletta JA, Kwiatkowski DJ, Meyerson M, Van Allen EM. Genomic landscape of high-grade T1 micropapillary bladder tumors. Journal of Clinical Oncology. 33: 299-299. DOI: 10.1200/Jco.2015.33.7_Suppl.299  0.427
2015 Fay AP, Kwiatkowski DJ, Gray KP, Thorner A, Rini BI, Agarwal N, Ho TH, Song J, Barrios PM, Albiges L, Van Allen EM, Krajewski KM, Porta C, Pal SK, Bellmunt J, et al. Activating genomic mutations in the mTOR pathway to predict responses to everolimus and temsirolimus in patients with metastatic renal cell carcinoma (mRCC): Results from a large multi-institutional cohort. Journal of Clinical Oncology. 33: 4519-4519. DOI: 10.1200/Jco.2015.33.15_Suppl.4519  0.461
2015 Chapuy B, Cheng H, Watahiki A, Ducar MD, Gusenleitner D, Chen L, Roemer MG, Quyang J, Christie AL, Zhang L, Tan Y, Abo RP, Bonin F, Thorner AR, Sun HH, et al. Diffuse Large B-Cell Lymphoma Patient-Derived Xenograft Models Capture Molecular and Biologic Heterogeneity and Inform Therapy Blood. 126: 817-817. DOI: 10.1182/Blood.V126.23.817.817  0.43
2015 Abo RP, Lin L, Hunter SS, Dolcen DN, Paquette RR, Laing A, Waal Ld, Thorner AR, Ducar MD, Ziaugra L, Hahn WC, Meyerson ML, MacConaill LE, Hummelen PV. Abstract 4867: Comparative analysis of RNA sequencing methods for characterization of cancer transcriptomics Cancer Research. 75: 4867-4867. DOI: 10.1158/1538-7445.Am2015-4867  0.339
2015 Brastianos PK, Carter SL, Santagata S, Taylor-Weiner A, Jones RT, Allen EV, Ligon KL, Tabernero J, Seoane J, Martinez-Saez E, Cahill D, Curry WT, Dunn IF, Paek SH, Hummelen PV, ... Thorner AR, et al. Abstract 4727: Genomic characterization of brain metastases reveals divergent evolution and metastasis specific mutations Brain. 75: 4727-4727. DOI: 10.1158/1538-7445.Am2015-4727  0.327
2015 Campbell J, Lathan C, Sholl L, Ducar M, Vega M, Lin L, Thorner A, Faris N, Hummelen Pv, Osarogiagbon R, Meyerson M, MacConaill L. Abstract 3886: Comparing the mutational landscape of African American and Caucasian lung cancers Cancer Research. 75: 3886-3886. DOI: 10.1158/1538-7445.Am2015-3886  0.322
2015 Lin L, Abo R, Dolcen D, Paquette R, Laing A, Waal Ld, Thorner A, Ducar M, Ziaugra L, Wollison B, Breneiser M, Hahn W, Meyerson M, Hummelen PV, MacConaill L. Abstract 1115: Targeted RNA sequencing improves transcript analysis in cancer samples Cancer Research. 75: 1115-1115. DOI: 10.1158/1538-7445.Am2015-1115  0.334
2015 Huynh M, Maire C, Abazeed M, Adams D, Pelton K, Pinnell N, Ramkissoon S, Korideck H, Van Hummelen P, Thorner A, Wen P, Ligon A, Schreiber S, Meyerson M, Ligon K, et al. Functional Profiling of a Glioblastoma (GBM) Patient-Derived Cell Line (PDCL) Panel Identifies Cell-Intrinsic Differential Radiation Response That Correlates With TP53 Mutations International Journal of Radiation Oncology*Biology*Physics. 93: E91-E92. DOI: 10.1016/J.Ijrobp.2015.07.779  0.351
2014 Calles A, Thorner AR, Sholl LM, Butaney M, Capelletti M, Mentzer SJ, van Hummelen P, Janne PA. 1180PDGENOMIC CHANGES IN LUNG CANCER PATIENTS WITH MULTIPLE LUNG RELAPSES. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 25: iv412. PMID 28172099 DOI: 10.1093/Annonc/Mdu347.8  0.414
2014 Shankar GM, Taylor-Weiner A, Lelic N, Jones RT, Kim JC, Francis JM, Abedalthagafi M, Borges LF, Coumans JV, Curry WT, Nahed BV, Shin JH, Paek SH, Park SH, Stewart C, ... ... Thorner AR, et al. Sporadic hemangioblastomas are characterized by cryptic VHL inactivation. Acta Neuropathologica Communications. 2: 167. PMID 25589003 DOI: 10.1186/S40478-014-0167-X  0.428
2014 Kim J, Fox C, Peng S, Pusung M, Pectasides E, Matthee E, Hong YS, Do IG, Jang J, Thorner AR, Van Hummelen P, Rustgi AK, Wong KK, Zhou Z, Tang P, et al. Preexisting oncogenic events impact trastuzumab sensitivity in ERBB2-amplified gastroesophageal adenocarcinoma. The Journal of Clinical Investigation. 124: 5145-58. PMID 25401468 DOI: 10.1172/Jci75200  0.38
2014 Hong YS, Kim J, Pectasides E, Fox C, Hong SW, Ma Q, Wong GS, Peng S, Stachler MD, Thorner AR, Van Hummelen P, Bass AJ. Src mutation induces acquired lapatinib resistance in ERBB2-amplified human gastroesophageal adenocarcinoma models. Plos One. 9: e109440. PMID 25350844 DOI: 10.1371/Journal.Pone.0109440  0.382
2014 Abedalthagafi MS, Merrill PH, Bi WL, Jones RT, Listewnik ML, Ramkissoon SH, Thorner AR, Dunn IF, Beroukhim R, Alexander BM, Brastianos PK, Francis JM, Folkerth RD, Ligon KL, Van Hummelen P, et al. Angiomatous meningiomas have a distinct genetic profile with multiple chromosomal polysomies including polysomy of chromosome 5. Oncotarget. 5: 10596-606. PMID 25347344 DOI: 10.18632/Oncotarget.2517  0.34
2014 Crompton BD, Stewart C, Taylor-Weiner A, Alexe G, Kurek KC, Calicchio ML, Kiezun A, Carter SL, Shukla SA, Mehta SS, Thorner AR, de Torres C, Lavarino C, Suñol M, McKenna A, et al. The genomic landscape of pediatric Ewing sarcoma. Cancer Discovery. 4: 1326-41. PMID 25186949 DOI: 10.1158/2159-8290.Cd-13-1037  0.439
2014 Brastianos PK, Taylor-Weiner A, Manley PE, Jones RT, Dias-Santagata D, Thorner AR, Lawrence MS, Rodriguez FJ, Bernardo LA, Schubert L, Sunkavalli A, Shillingford N, Calicchio ML, Lidov HG, Taha H, et al. Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas. Nature Genetics. 46: 161-5. PMID 24413733 DOI: 10.1038/Ng.2868  0.432
2014 Crompton B, Stewart C, Taylor-Weiner A, Alexa G, Kurek K, Calicchio M, Kiezun A, Carter S, Shukla S, Mehta S, Thorner A, Torres Cd, Lavarino C, Sunol M, McKenna A, et al. Abstract 999: The genomic landscape of pediatric Ewing sarcoma Cancer Research. 74: 999-999. DOI: 10.1158/1538-7445.Am2014-999  0.461
2014 Taylor-Weiner AN, Brastianos PK, Manley PE, Jones RT, Dias-Sangata D, Thorner A, Rodriguez F, Bernardo L, Schubert L, Stewart C, Keiran M, Hahn WC, Resnick A, Louis D, Sangata S, et al. Abstract 935: Exome sequencing reveals BRAF mutations in papillary craniopharyngiomas Cancer Research. 74: 935-935. DOI: 10.1158/1538-7445.Am2014-935  0.439
2014 Thorner AR, Sunkavalli A, Lin L, Jones RT, Schubert L, Ducar MD, Adusumilli R, Dolcen DN, Ziaugra L, Lepine J, MacConaill LE, Hahn WC, Meyerson M, Hummelen PV. Abstract 3583: Reducing GC-bias and improving coverage distribution in Illumina sequencing using the Kapa Biosystems library construction method Cancer Research. 74: 3583-3583. DOI: 10.1158/1538-7445.Am2014-3583  0.341
2014 Brastianos P, Taylor-Weiner A, Manley P, Jones R, Dias-Santagata D, Thorner A, Rodriguez F, Bernardo L, Schubert L, Stewart C, Kieran M, Louis D, Getz G, Santagata S. GE-05 * EXOME SEQUENCING REVEALS BRAF MUTATIONS IN PAPILLARY CRANIOPHARYNGIOMAS Neuro-Oncology. 16: v97-v97. DOI: 10.1093/Neuonc/Nou256.5  0.426
2013 Crompton BD, Carlton AL, Thorner AR, Christie AL, Du J, Calicchio ML, Rivera MN, Fleming MD, Kohl NE, Kung AL, Stegmaier K. High-throughput tyrosine kinase activity profiling identifies FAK as a candidate therapeutic target in Ewing sarcoma. Cancer Research. 73: 2873-83. PMID 23536552 DOI: 10.1158/0008-5472.Can-12-1944  0.349
2010 Thorner AR, Parker JS, Hoadley KA, Perou CM. Potential tumor suppressor role for the c-Myb oncogene in luminal breast cancer. Plos One. 5: e13073. PMID 20949095 DOI: 10.1371/Journal.Pone.0013073  0.669
2010 Deisenroth C, Thorner AR, Enomoto T, Perou CM, Zhang Y. Mitochondrial Hep27 is a c-Myb target gene that inhibits Mdm2 and stabilizes p53. Molecular and Cellular Biology. 30: 3981-93. PMID 20547751 DOI: 10.1128/Mcb.01284-09  0.474
2009 Thorner AR, Hoadley KA, Parker JS, Winkel S, Millikan RC, Perou CM. In vitro and in vivo analysis of B-Myb in basal-like breast cancer. Oncogene. 28: 742-51. PMID 19043454 DOI: 10.1038/Onc.2008.430  0.676
2006 Febbo PG, Thorner A, Rubin MA, Loda M, Kantoff PW, Oh WK, Golub T, George D. Application of oligonucleotide microarrays to assess the biological effects of neoadjuvant imatinib mesylate treatment for localized prostate cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 152-8. PMID 16397037 DOI: 10.1158/1078-0432.Ccr-05-1652  0.31
2005 Wang J, Iwasaki H, Krivtsov A, Febbo PG, Thorner AR, Ernst P, Anastasiadou E, Kutok JL, Kogan SC, Zinkel SS, Fisher JK, Hess JL, Golub TR, Armstrong SA, Akashi K, et al. Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease. The Embo Journal. 24: 368-81. PMID 15635450 DOI: 10.1038/Sj.Emboj.7600521  0.304
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