Year |
Citation |
Score |
2019 |
Flynn J, Cox K, Touch S, Ou Y, Weber T, Citron M, Bahl K, Ciaramella G, Espeseth A, Zhang L. 2729. mRNA Vaccines Encoding Conserved Influenza Antigens Induce Robust and Durable Immunity in Rhesus Macaques Open Forum Infectious Diseases. 6. DOI: 10.1093/Ofid/Ofz360.2407 |
0.311 |
|
2018 |
Najar TA, Kar U, Flynn JA, Varadarajan R. Isolation of an in vitro affinity-matured, thermostable "Headless" HA stem fragment that binds broadly neutralizing antibodies with high affinity. Biochemistry. PMID 29863853 DOI: 10.1021/Acs.Biochem.8B00267 |
0.32 |
|
2016 |
Kesavardhana S, Das R, Citron M, Datta R, Ecto L, Srilatha NS, DiStefano D, Swoyer R, Joyce JG, Dutta S, LaBranche CC, Montefiori DC, Flynn JA, Varadarajan R. Structure based design of cyclically permuted HIV-1 gp120 trimers that elicit neutralizing antibodies. The Journal of Biological Chemistry. PMID 27879316 DOI: 10.1074/Jbc.M116.725614 |
0.337 |
|
2016 |
Flynn JA, Durr E, Swoyer R, Cejas PJ, Horton MS, Galli JD, Cosmi SA, Espeseth AS, Bett AJ, Zhang L. Stability Characterization of a Vaccine Antigen Based on the Respiratory Syncytial Virus Fusion Glycoprotein. Plos One. 11: e0164789. PMID 27764150 DOI: 10.1371/Journal.Pone.0164789 |
0.324 |
|
2015 |
Mallajosyula VV, Citron M, Ferrara F, Temperton NJ, Liang X, Flynn JA, Varadarajan R. Hemagglutinin Sequence Conservation Guided Stem Immunogen Design from Influenza A H3 Subtype. Frontiers in Immunology. 6: 329. PMID 26167164 DOI: 10.3389/Fimmu.2015.00329 |
0.343 |
|
2014 |
Mallajosyula VV, Citron M, Ferrara F, Lu X, Callahan C, Heidecker GJ, Sarma SP, Flynn JA, Temperton NJ, Liang X, Varadarajan R. Influenza hemagglutinin stem-fragment immunogen elicits broadly neutralizing antibodies and confers heterologous protection. Proceedings of the National Academy of Sciences of the United States of America. 111: E2514-23. PMID 24927560 DOI: 10.1073/Pnas.1402766111 |
0.332 |
|
2014 |
Awasthi S, Balliet JW, Flynn JA, Lubinski JM, Shaw CE, DiStefano DJ, Cai M, Brown M, Smith JF, Kowalski R, Swoyer R, Galli J, Copeland V, Rios S, Davidson RC, et al. Protection provided by a herpes simplex virus 2 (HSV-2) glycoprotein C and D subunit antigen vaccine against genital HSV-2 infection in HSV-1-seropositive guinea pigs. Journal of Virology. 88: 2000-10. PMID 24284325 DOI: 10.1128/Jvi.03163-13 |
0.327 |
|
2012 |
Awasthi S, Zumbrun EE, Si H, Wang F, Shaw CE, Cai M, Lubinski JM, Barrett SM, Balliet JW, Flynn JA, Casimiro DR, Bryan JT, Friedman HM. Live attenuated herpes simplex virus 2 glycoprotein E deletion mutant as a vaccine candidate defective in neuronal spread. Journal of Virology. 86: 4586-98. PMID 22318147 DOI: 10.1128/Jvi.07203-11 |
0.349 |
|
2011 |
Gomez R, Jolly SJ, Williams T, Vacca JP, Torrent M, McGaughey G, Lai MT, Felock P, Munshi V, Distefano D, Flynn J, Miller M, Yan Y, Reid J, Sanchez R, et al. Design and synthesis of conformationally constrained inhibitors of non-nucleoside reverse transcriptase. Journal of Medicinal Chemistry. 54: 7920-33. PMID 21985673 DOI: 10.1021/Jm2010173 |
0.354 |
|
2011 |
Awasthi S, Lubinski JM, Shaw CE, Barrett SM, Cai M, Wang F, Betts M, Kingsley S, Distefano DJ, Balliet JW, Flynn JA, Casimiro DR, Bryan JT, Friedman HM. Immunization with a vaccine combining herpes simplex virus 2 (HSV-2) glycoprotein C (gC) and gD subunits improves the protection of dorsal root ganglia in mice and reduces the frequency of recurrent vaginal shedding of HSV-2 DNA in guinea pigs compared to immunization with gD alone. Journal of Virology. 85: 10472-86. PMID 21813597 DOI: 10.1128/Jvi.00849-11 |
0.311 |
|
2010 |
Su DS, Lim JJ, Tinney E, Tucker TJ, Saggar S, Sisko JT, Wan BL, Young MB, Anderson KD, Rudd D, Munshi V, Bahnck C, Felock PJ, Lu M, Lai MT, ... ... Flynn JA, et al. Biaryl ethers as potent allosteric inhibitors of reverse transcriptase and its key mutant viruses: aryl substituted pyrazole as a surrogate for the pyrazolopyridine motif. Bioorganic & Medicinal Chemistry Letters. 20: 4328-32. PMID 20609585 DOI: 10.1016/J.Bmcl.2010.06.083 |
0.325 |
|
2010 |
Casimiro DR, Cox K, Tang A, Sykes KJ, Feng M, Wang F, Bett A, Schleif WA, Liang X, Flynn J, Tobery TW, Wilson K, Finnefrock A, Huang L, Vitelli S, et al. Efficacy of multivalent adenovirus-based vaccine against simian immunodeficiency virus challenge. Journal of Virology. 84: 2996-3003. PMID 20042509 DOI: 10.1128/Jvi.00969-09 |
0.353 |
|
2009 |
Su DS, Lim JJ, Tinney E, Wan BL, Young MB, Anderson KD, Rudd D, Munshi V, Bahnck C, Felock PJ, Lu M, Lai MT, Touch S, Moyer G, Distefano DJ, ... Flynn JA, et al. Substituted tetrahydroquinolines as potent allosteric inhibitors of reverse transcriptase and its key mutants. Bioorganic & Medicinal Chemistry Letters. 19: 5119-23. PMID 19631528 DOI: 10.1016/J.Bmcl.2009.07.031 |
0.301 |
|
2008 |
Tucker TJ, Sisko JT, Tynebor RM, Williams TM, Felock PJ, Flynn JA, Lai MT, Liang Y, McGaughey G, Liu M, Miller M, Moyer G, Munshi V, Perlow-Poehnelt R, Prasad S, et al. Discovery of 3-{5-[(6-amino-1H-pyrazolo[3,4-b]pyridine-3-yl)methoxy]-2-chlorophenoxy}-5-chlorobenzonitrile (MK-4965): a potent, orally bioavailable HIV-1 non-nucleoside reverse transcriptase inhibitor with improved potency against key mutant viruses. Journal of Medicinal Chemistry. 51: 6503-11. PMID 18826204 DOI: 10.1021/Jm800856C |
0.327 |
|
2006 |
Flynn JA, Telesnitsky A. Two distinct Moloney murine leukemia virus RNAs produced from a single locus dimerize at random. Virology. 344: 391-400. PMID 16216294 DOI: 10.1016/J.Virol.2005.09.002 |
0.602 |
|
2004 |
Flynn JA, An W, King SR, Telesnitsky A. Nonrandom dimerization of murine leukemia virus genomic RNAs. Journal of Virology. 78: 12129-39. PMID 15507599 DOI: 10.1128/Jvi.78.22.12129-12139.2004 |
0.578 |
|
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