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Bin Z He, Ph.D. - Publications

Affiliations: 
2006-2012 Ecology and Evolution University of Chicago, Chicago, IL 
 2012-2017 FAS Center for Systems Biology Harvard University, Cambridge, MA, United States 
 2018- Biology University of Iowa, Iowa City, IA 
Area:
Gene regulatory evolution, stress response, pathogenic fungi
Website:
binhe-lab.org
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41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Liu X, Matrenec R, Gack MU, He B. Disassembly of the TRIM23-TBK1 Complex by the Us11 Protein of Herpes Simplex Virus 1 Impairs Autophagy. Journal of Virology. PMID 31189704 DOI: 10.1128/Jvi.00497-19  0.364
2018 Liu X, He B. Selective Editing of HSV-1 Enables IFN Induction and Viral Replication That Destruct Malignant Cells. Journal of Virology. PMID 30404809 DOI: 10.1128/Jvi.01761-18  0.357
2018 Pan S, Liu X, Ma Y, Cao Y, He B. The Herpes Simplex Virus 1 γ34.5 Protein Inhibits STING Activation That Restricts Viral Replication. Journal of Virology. PMID 30045990 DOI: 10.1128/Jvi.01015-18  0.379
2018 Liu X, Main D, Ma Y, He B. Herpes Simplex Virus 1 Inhibits TANK-Binding Kinase 1 through Formation of the Us11-Hsp90 Complex. Journal of Virology. PMID 29743370 DOI: 10.1128/Jvi.00402-18  0.367
2017 Xiao X, Lei X, Zhang Z, Ma Y, Qi J, Wu C, Xiao Y, Li L, He B, Wang J. Enterovirus 3A facilitates viral replication by promoting PI4KB-ACBD3 interaction. Journal of Virology. PMID 28701404 DOI: 10.1128/Jvi.00791-17  0.325
2017 Lei X, Zhang Z, Xiao X, Qi J, He B, Wang J. Enterovirus 71 inhibits pyroptosis through cleavage of GSDMD. Journal of Virology. PMID 28679757 DOI: 10.1128/Jvi.01069-17  0.338
2015 Wang H, Lei X, Xiao X, Yang C, Lu W, Huang Z, Leng Q, Jin Q, He B, Meng G, Wang J. Reciprocal Regulation between Enterovirus 71 and the NLRP3 Inflammasome. Cell Reports. PMID 26119741 DOI: 10.1016/J.Celrep.2015.05.047  0.301
2015 Yang Y, Wu S, Wang Y, Pan S, Lan B, Liu Y, Zhang L, Leng Q, Chen D, Zhang C, He B, Cao Y. The Us3 Protein of Herpes Simplex Virus 1 Inhibits T Cell Signaling by Confining Linker for Activation of T Cells (LAT) Activation via TRAF6 Protein. The Journal of Biological Chemistry. 290: 15670-8. PMID 25907557 DOI: 10.1074/Jbc.M115.646422  0.335
2014 Wang Y, Yang Y, Wu S, Pan S, Zhou C, Ma Y, Ru Y, Dong S, He B, Zhang C, Cao Y. p32 is a novel target for viral protein ICP34.5 of herpes simplex virus type 1 and facilitates viral nuclear egress. The Journal of Biological Chemistry. 289: 35795-805. PMID 25355318 DOI: 10.1074/Jbc.M114.603845  0.327
2014 Lei X, Han N, Xiao X, Jin Q, He B, Wang J. Enterovirus 71 3C inhibits cytokine expression through cleavage of the TAK1/TAB1/TAB2/TAB3 complex. Journal of Virology. 88: 9830-41. PMID 24942571 DOI: 10.1128/Jvi.01425-14  0.314
2014 Xiang Z, Li L, Lei X, Zhou H, Zhou Z, He B, Wang J. Enterovirus 68 3C protease cleaves TRIF to attenuate antiviral responses mediated by Toll-like receptor 3. Journal of Virology. 88: 6650-9. PMID 24672048 DOI: 10.1128/Jvi.03138-13  0.325
2014 Zhou Z, Jia X, Xue Q, Dou Z, Ma Y, Zhao Z, Jiang Z, He B, Jin Q, Wang J. TRIM14 is a mitochondrial adaptor that facilitates retinoic acid-inducible gene-I-like receptor-mediated innate immune response. Proceedings of the National Academy of Sciences of the United States of America. 111: E245-54. PMID 24379373 DOI: 10.1073/Pnas.1316941111  0.327
2014 He BZ, Ludwig MZ, Dickerson DA, Barse L, Arun B, Vilhjálmsson BJ, Jiang P, Park SY, Tamarina NA, Selleck SB, Wittkopp PJ, Bell GI, Kreitman M. Effect of genetic variation in a Drosophila model of diabetes-associated misfolded human proinsulin. Genetics. 196: 557-67. PMID 24281155 DOI: 10.1534/Genetics.113.157800  0.555
2014 Park SY, Ludwig MZ, Tamarina NA, He BZ, Carl SH, Dickerson DA, Barse L, Arun B, Williams CL, Miles CM, Philipson LH, Steiner DF, Bell GI, Kreitman M. Genetic complexity in a Drosophila model of diabetes-associated misfolded human proinsulin. Genetics. 196: 539-55. PMID 24281154 DOI: 10.1534/Genetics.113.157602  0.596
2014 Ma Y, He B. Recognition of herpes simplex viruses: toll-like receptors and beyond. Journal of Molecular Biology. 426: 1133-47. PMID 24262390 DOI: 10.1016/J.Jmb.2013.11.012  0.313
2013 Lei X, Xiao X, Xue Q, Jin Q, He B, Wang J. Cleavage of interferon regulatory factor 7 by enterovirus 71 3C suppresses cellular responses. Journal of Virology. 87: 1690-8. PMID 23175366 DOI: 10.1128/Jvi.01855-12  0.38
2012 Ma Y, Jin H, Valyi-Nagy T, Cao Y, Yan Z, He B. Inhibition of TANK binding kinase 1 by herpes simplex virus 1 facilitates productive infection. Journal of Virology. 86: 2188-96. PMID 22171259 DOI: 10.1128/Jvi.05376-11  0.362
2011 Lei X, Sun Z, Liu X, Jin Q, He B, Wang J. Cleavage of the Adaptor Protein TRIF by Enterovirus 71 3C Inhibits Antiviral Responses Mediated by Toll-Like Receptor 3 Journal of Virology. 85: 8811-8818. PMID 21697485 DOI: 10.1128/Jvi.00447-11  0.358
2011 He BZ, Holloway AK, Maerkl SJ, Kreitman M. Does positive selection drive transcription factor binding site turnover? A test with Drosophila cis-regulatory modules. Plos Genetics. 7: e1002053. PMID 21572512 DOI: 10.1371/Journal.Pgen.1002053  0.51
2011 Jin H, Yan Z, Ma Y, Cao Y, He B. A herpesvirus virulence factor inhibits dendritic cell maturation through protein phosphatase 1 and Ikappa B kinase. Journal of Virology. 85: 3397-407. PMID 21248029 DOI: 10.1128/Jvi.02373-10  0.346
2010 Lei X, Liu X, Ma Y, Sun Z, Yang Y, Jin Q, He B, Wang J. The 3C protein of enterovirus 71 inhibits retinoid acid-inducible gene I-mediated interferon regulatory factor 3 activation and type I interferon responses. Journal of Virology. 84: 8051-61. PMID 20519382 DOI: 10.1128/Jvi.02491-09  0.389
2010 Jin H, Yan Z, Prabhakar BS, Feng Z, Ma Y, Verpooten D, Ganesh B, He B. The VP35 protein of Ebola virus impairs dendritic cell maturation induced by virus and lipopolysaccharide. The Journal of General Virology. 91: 352-61. PMID 19828757 DOI: 10.1099/Vir.0.017343-0  0.333
2009 Verpooten D, Ma Y, Hou S, Yan Z, He B. Control of TANK-binding kinase 1-mediated signaling by the gamma(1)34.5 protein of herpes simplex virus 1. The Journal of Biological Chemistry. 284: 1097-105. PMID 19010780 DOI: 10.1074/Jbc.M805905200  0.398
2008 Ma Y, Verpooten D, He B. Herpes simplex viruses and induction of interferon responses Virologica Sinica. 23: 416-428. DOI: 10.1007/S12250-008-2999-7  0.315
2007 Feng Z, Cerveny M, Yan Z, He B. The VP35 protein of Ebola virus inhibits the antiviral effect mediated by double-stranded RNA-dependent protein kinase PKR. Journal of Virology. 81: 182-92. PMID 17065211 DOI: 10.1128/Jvi.01006-06  0.366
2005 Jing X, He B. Characterization of the triplet repeats in the central domain of the gamma134.5 protein of herpes simplex virus 1. The Journal of General Virology. 86: 2411-9. PMID 16099898 DOI: 10.1099/Vir.0.81033-0  0.35
2005 Hellums EK, Markert JM, Parker JN, He B, Perbal B, Roizman B, Whitley RJ, Langford CP, Bharara S, Gillespie GY. Increased efficacy of an interleukin-12-secreting herpes simplex virus in a syngeneic intracranial murine glioma model. Neuro-Oncology. 7: 213-24. PMID 16053696 DOI: 10.1215/S1152851705000074  0.349
2005 Cheng G, Feng Z, He B. Herpes simplex virus 1 infection activates the endoplasmic reticulum resident kinase PERK and mediates eIF-2alpha dephosphorylation by the gamma(1)34.5 protein. Journal of Virology. 79: 1379-88. PMID 15650164 DOI: 10.1128/Jvi.79.3.1379-1388.2005  0.352
2004 Jing X, Cerveny M, Yang K, He B. Replication of herpes simplex virus 1 depends on the γ134. 5 functions that facilitate virus response to interferon and egress in the different stages of productive infection Journal of Virology. 78: 7653-7666. PMID 15220440 DOI: 10.1128/Jvi.78.14.7653-7666.2004  0.367
2003 Cheng G, Yang K, He B. Dephosphorylation of eIF-2alpha mediated by the gamma(1)34.5 protein of herpes simplex virus type 1 is required for viral response to interferon but is not sufficient for efficient viral replication. Journal of Virology. 77: 10154-61. PMID 12941928 DOI: 10.1128/Jvi.77.18.10154-10161.2003  0.356
2003 Cerveny M, Hessefort S, Yang K, Cheng G, Gross M, He B. Amino acid substitutions in the effector domain of the γ134.5 protein of herpes simplex virus 1 have differential effects on viral response to interferon-α Virology. 307: 290-300. PMID 12667799 DOI: 10.1016/S0042-6822(02)00075-2  0.349
2002 Cheng G, Brett ME, He B. Signals that dictate nuclear, nucleolar, and cytoplasmic shuttling of the gamma(1)34.5 protein of herpes simplex virus type 1. Journal of Virology. 76: 9434-45. PMID 12186925 DOI: 10.1128/Jvi.76.18.9434-9445.2002  0.352
2001 Cheng G, Brett ME, He B. Val193 and Phe195 of the gamma 1 34.5 protein of herpes simplex virus 1 are required for viral resistance to interferon-alpha/beta. Virology. 290: 115-20. PMID 11882996 DOI: 10.1006/Viro.2001.1148  0.315
2001 Cheng G, Gross M, Brett ME, He B. AlaArg motif in the carboxyl terminus of the gamma(1)34.5 protein of herpes simplex virus type 1 is required for the formation of a high-molecular-weight complex that dephosphorylates eIF-2alpha. Journal of Virology. 75: 3666-74. PMID 11264356 DOI: 10.1128/Jvi.75.8.3666-3674.2001  0.329
1999 Perbal B, Martinerie C, Sainson R, Werner M, He B, Roizman B. The C-terminal domain of the regulatory protein NOVH is sufficient to promote interaction with fibulin 1C: a clue for a role of NOVH in cell-adhesion signaling. Proceedings of the National Academy of Sciences of the United States of America. 96: 869-74. PMID 9927660 DOI: 10.1073/Pnas.96.3.869  0.317
1998 He B, Gross M, Roizman B. The gamma134.5 protein of herpes simplex virus 1 has the structural and functional attributes of a protein phosphatase 1 regulatory subunit and is present in a high molecular weight complex with the enzyme in infected cells. The Journal of Biological Chemistry. 273: 20737-43. PMID 9694816 DOI: 10.1074/Jbc.273.33.20737  0.324
1998 Andreansky S, He B, van Cott J, McGhee J, Markert JM, Gillespie GY, Roizman B, Whitley RJ. Treatment of intracranial gliomas in immunocompetent mice using herpes simplex viruses that express murine interleukins. Gene Therapy. 5: 121-30. PMID 9536273 DOI: 10.1038/Sj.Gt.3300550  0.311
1997 He B, Chou J, Brandimarti R, Mohr I, Gluzman Y, Roizman B. Suppression of the phenotype of gamma(1)34.5- herpes simplex virus 1: failure of activated RNA-dependent protein kinase to shut off protein synthesis is associated with a deletion in the domain of the alpha47 gene. Journal of Virology. 71: 6049-54. PMID 9223497 DOI: 10.1128/Jvi.71.8.6049-6054.1997  0.369
1997 He B, Gross M, Roizman B. The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-activated protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 94: 843-8. PMID 9023344 DOI: 10.1073/Pnas.94.3.843  0.34
1996 Andreansky SS, He B, Gillespie GY, Soroceanu L, Markert J, Chou J, Roizman B, Whitley RJ. The application of genetically engineered herpes simplex viruses to the treatment of experimental brain tumors. Proceedings of the National Academy of Sciences of the United States of America. 93: 11313-8. PMID 8876132 DOI: 10.1073/Pnas.93.21.11313  0.315
1996 He B, Chou J, Liebermann DA, Hoffman B, Roizman B. The carboxyl terminus of the murine MyD116 gene substitutes for the corresponding domain of the gamma(1)34.5 gene of herpes simplex virus to preclude the premature shutoff of total protein synthesis in infected human cells. Journal of Virology. 70: 84-90. PMID 8523596 DOI: 10.1128/Jvi.70.1.84-90.1996  0.379
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