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Anton P. McCaffrey - Publications

Affiliations: 
Molecular & Cell Biology University of Iowa, Iowa City, IA 
Area:
General Biology, Molecular Biology, Cell Biology
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31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Jiang T, Henderson JM, Coote K, Cheng Y, Valley HC, Zhang XO, Wang Q, Rhym LH, Cao Y, Newby GA, Bihler H, Mense M, Weng Z, Anderson DG, McCaffrey AP, et al. Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope. Nature Communications. 11: 1979. PMID 32332735 DOI: 10.1038/S41467-020-15892-8  0.367
2018 Khnouf R, Shore S, Han CM, Henderson JM, Munro SA, McCaffrey AP, Shintaku H, Santiago JG. Efficient Production of On-Target Reads for Small RNA Sequencing of Single Cells Using Modified Adapters. Analytical Chemistry. PMID 30260208 DOI: 10.1021/Acs.Analchem.8B02773  0.38
2018 Vaidyanathan S, Azizian KT, Haque AKMA, Henderson JM, Hendel A, Shore S, Antony JS, Hogrefe RI, Kormann MSD, Porteus MH, McCaffrey AP. Uridine Depletion and Chemical Modification Increase Cas9 mRNA Activity and Reduce Immunogenicity without HPLC Purification. Molecular Therapy. Nucleic Acids. 12: 530-542. PMID 30195789 DOI: 10.1016/J.Omtn.2018.06.010  0.312
2018 Shore S, Henderson JM, McCaffrey AP. CleanTag Adapters Improve Small RNA Next-Generation Sequencing Library Preparation by Reducing Adapter Dimers. Methods in Molecular Biology (Clifton, N.J.). 1712: 145-161. PMID 29224073 DOI: 10.1007/978-1-4939-7514-3_10  0.324
2016 Shore S, Henderson JM, Lebedev A, Salcedo MP, Zon G, McCaffrey AP, Paul N, Hogrefe RI. Small RNA Library Preparation Method for Next-Generation Sequencing Using Chemical Modifications to Prevent Adapter Dimer Formation. Plos One. 11: e0167009. PMID 27875576 DOI: 10.1371/Journal.Pone.0167009  0.304
2016 Urak KT, Shore S, Rockey WM, Chen SJ, McCaffrey AP, Giangrande PH. In vitro RNA SELEX for the generation of chemically-optimized therapeutic RNA drugs. Methods (San Diego, Calif.). PMID 26972786 DOI: 10.1016/J.Ymeth.2016.03.003  0.353
2015 McCaffrey AP, Lebedev A, Shin D, Azizian K, Escamilla-Powers JR, Midthune B, Yokoe H, Jessee J, Hogrefe RI. 651. Making the Optimal Messenger RNA for Gene Therapy Applications: Evaluation of Novel Nucleotide Modifications for Improved Activity Molecular Therapy. 23: S259. DOI: 10.1016/S1525-0016(16)34260-5  0.312
2013 Snead NM, Escamilla-Powers JR, Rossi JJ, McCaffrey AP. 5' Unlocked Nucleic Acid Modification Improves siRNA Targeting. Molecular Therapy. Nucleic Acids. 2: e103. PMID 23820891 DOI: 10.1038/Mtna.2013.36  0.402
2012 Graff JW, Dickson AM, Clay G, McCaffrey AP, Wilson ME. Identifying functional microRNAs in macrophages with polarized phenotypes. The Journal of Biological Chemistry. 287: 21816-25. PMID 22549785 DOI: 10.1074/Jbc.M111.327031  0.439
2012 Wendlandt EB, Graff JW, Gioannini TL, McCaffrey AP, Wilson ME. The role of microRNAs miR-200b and miR-200c in TLR4 signaling and NF-κB activation. Innate Immunity. 18: 846-55. PMID 22522429 DOI: 10.1177/1753425912443903  0.42
2012 Ramirez CL, Certo MT, Mussolino C, Goodwin MJ, Cradick TJ, McCaffrey AP, Cathomen T, Scharenberg AM, Joung JK. Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects. Nucleic Acids Research. 40: 5560-8. PMID 22373919 DOI: 10.1093/Nar/Gks179  0.646
2011 Bandyopadhyay S, Friedman RC, Marquez RT, Keck K, Kong B, Icardi MS, Brown KE, Burge CB, Schmidt WN, Wang Y, McCaffrey AP. Hepatitis C virus infection and hepatic stellate cell activation downregulate miR-29: miR-29 overexpression reduces hepatitis C viral abundance in culture. The Journal of Infectious Diseases. 203: 1753-62. PMID 21606534 DOI: 10.1093/Infdis/Jir186  0.669
2011 Cradick TJ, Ambrosini G, Iseli C, Bucher P, McCaffrey AP. ZFN-site searches genomes for zinc finger nuclease target sites and off-target sites. Bmc Bioinformatics. 12: 152. PMID 21569489 DOI: 10.1186/1471-2105-12-152  0.642
2010 Marquez RT, Bandyopadhyay S, Wendlandt EB, Keck K, Hoffer BA, Icardi MS, Christensen RN, Schmidt WN, McCaffrey AP. Correlation between microRNA expression levels and clinical parameters associated with chronic hepatitis C viral infection in humans. Laboratory Investigation; a Journal of Technical Methods and Pathology. 90: 1727-36. PMID 20625373 DOI: 10.1038/Labinvest.2010.126  0.665
2010 Marquez RT, Wendlandt E, Galle CS, Keck K, McCaffrey AP. MicroRNA-21 is upregulated during the proliferative phase of liver regeneration, targets Pellino-1, and inhibits NF-kappaB signaling. American Journal of Physiology. Gastrointestinal and Liver Physiology. 298: G535-41. PMID 20167875 DOI: 10.1152/Ajpgi.00338.2009  0.66
2010 Cradick TJ, Keck K, Bradshaw S, Jamieson AC, McCaffrey AP. Zinc-finger nucleases as a novel therapeutic strategy for targeting hepatitis B virus DNAs. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 947-54. PMID 20160705 DOI: 10.1038/Mt.2010.20  0.67
2009 McCaffrey AP. RNA interference inhibitors of hepatitis B virus. Annals of the New York Academy of Sciences. 1175: 15-23. PMID 19796073 DOI: 10.1111/J.1749-6632.2009.04974.X  0.447
2009 Dassie JP, Liu XY, Thomas GS, Whitaker RM, Thiel KW, Stockdale KR, Meyerholz DK, McCaffrey AP, McNamara JO, Giangrande PH. Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors. Nature Biotechnology. 27: 839-49. PMID 19701187 DOI: 10.1038/Nbt.1560  0.321
2009 Keck K, Volper EM, Spengler RM, Long DD, Chan CY, Ding Y, McCaffrey AP. Rational design leads to more potent RNA interference against hepatitis B virus: factors effecting silencing efficiency. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 538-47. PMID 19088704 DOI: 10.1038/Mt.2008.273  0.424
2009 Staber JM, Burnight E, Sarvida ME, McCaffrey A, Kaminski J, McCray P. Gene Transfer Targeting Hepatocytes Using the PiggyBac Transposon System: An Approach towards Hemophilia A Correction and Long Term Expression of Factor VIII. Blood. 114: 3575-3575. DOI: 10.1182/Blood.V114.22.3575.3575  0.355
2008 McCaffrey AP, Fawcett P, Nakai H, McCaffrey RL, Ehrhardt A, Pham TT, Pandey K, Xu H, Feuss S, Storm TA, Kay MA. The host response to adenovirus, helper-dependent adenovirus, and adeno-associated virus in mouse liver. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 931-41. PMID 18388926 DOI: 10.1038/Mt.2008.37  0.314
2008 Marquez RT, McCaffrey AP. Advances in microRNAs: implications for gene therapists. Human Gene Therapy. 19: 27-38. PMID 18092919 DOI: 10.1089/Hum.2007.147  0.631
2004 Layzer JM, McCaffrey AP, Tanner AK, Huang Z, Kay MA, Sullenger BA. In vivo activity of nuclease-resistant siRNAs. Rna (New York, N.Y.). 10: 766-71. PMID 15100431 DOI: 10.1261/Rna.5239604  0.343
2004 Grimm D, Streetz KL, Storm TA, Nakai H, McCaffrey AP, Huang Z, Salazar FH, Marion PL, Kay MA. 371. Complete Inhibition of Hepatitis B Virus Gene Expression In Vivo with Short Hairpin RNA Expressed from a Novel Double-Stranded, Bi-Cistronic Adeno-Associated Virus Pseudotype 8 Vector Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.918  0.377
2004 McCaffrey AP, Pandey K, Ehrhardt A, Huang Z, Kay MA. 58. Toward Adenoviral Mediated RNA Interference for the Treatment of Hepatitis B Virus Infection|[ast]| Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.05.039  0.423
2003 McCaffrey AP, Meuse L, Karimi M, Contag CH, Kay MA. A potent and specific morpholino antisense inhibitor of hepatitis C translation in mice. Hepatology (Baltimore, Md.). 38: 503-8. PMID 12883495 DOI: 10.1053/Jhep.2003.50330  0.372
2003 McCaffrey AP, Nakai H, Pandey K, Huang Z, Salazar FH, Xu H, Wieland SF, Marion PL, Kay MA. Inhibition of hepatitis B virus in mice by RNA interference. Nature Biotechnology. 21: 639-44. PMID 12740585 DOI: 10.1038/Nbt824  0.4
2002 McCaffrey AP, Kay MA. A story of mice and men. Gene Therapy. 9: 1563. PMID 12424608 DOI: 10.1038/Sj.Gt.3301890  0.376
2002 McCaffrey AP, Meuse L, Pham TT, Conklin DS, Hannon GJ, Kay MA. RNA interference in adult mice. Nature. 418: 38-9. PMID 12097900 DOI: 10.1038/418038A  0.381
2002 McCaffrey AP, Ohashi K, Meuse L, Shen S, Lancaster AM, Lukavsky PJ, Sarnow P, Kay MA. Determinants of hepatitis C translational initiation in vitro, in cultured cells and mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 5: 676-84. PMID 12027551 DOI: 10.1006/Mthe.2002.0600  0.387
1992 Reynolds MA, Beck TA, Hogrefe RI, McCaffrey A, Arnold LJ, Vaghefi MM. A non-nucleotide-based linking method for the preparation of psoralen-derivatized methylphosphonate oligonucleotides. Bioconjugate Chemistry. 3: 366-74. PMID 1420436 DOI: 10.1021/Bc00017A003  0.374
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