| Year |
Citation |
Score |
| 2019 |
Errington WJ, Bruncsics B, Sarkar CA. Mechanisms of noncanonical binding dynamics in multivalent protein-protein interactions. Proceedings of the National Academy of Sciences of the United States of America. PMID 31776263 DOI: 10.1073/Pnas.1902909116 |
0.343 |
|
| 2019 |
Shah NA, Sarkar CA. Variable cellular decision-making behavior in a constant synthetic network topology. Bmc Bioinformatics. 20: 237. PMID 31088350 DOI: 10.1186/S12859-019-2866-6 |
0.533 |
|
| 2018 |
Ye Z, Sarkar CA. Towards a Quantitative Understanding of Cell Identity. Trends in Cell Biology. PMID 30309735 DOI: 10.1016/J.Tcb.2018.09.002 |
0.322 |
|
| 2017 |
Sadler FW, Dodevski I, Sarkar CA. RNA Thermometers for the PURExpress System. Acs Synthetic Biology. PMID 29271642 DOI: 10.1021/Acssynbio.7B00294 |
0.39 |
|
| 2015 |
Shah NA, Levesque MJ, Raj A, Sarkar CA. Robust hematopoietic progenitor cell commitment in the presence of a conflicting cue. Journal of Cell Science. 128: 4024. PMID 26527202 DOI: 10.1242/Jcs.180653 |
0.471 |
|
| 2015 |
Shah NA, Levesque MJ, Raj A, Sarkar CA. Robust hematopoietic progenitor cell commitment in a noisy environment via suppression of a conflicting signal. Journal of Cell Science. PMID 26159733 DOI: 10.1242/Jcs.158436 |
0.547 |
|
| 2015 |
Dodevski I, Markou GC, Sarkar CA. Conceptual and methodological advances in cell-free directed evolution. Current Opinion in Structural Biology. 33: 1-7. PMID 26093059 DOI: 10.1016/J.Sbi.2015.04.008 |
0.349 |
|
| 2015 |
Shah NA, Sarkar CA. Computationally guided design of robust gene circuits. Methods in Molecular Biology (Clifton, N.J.). 1244: 167-78. PMID 25487097 DOI: 10.1007/978-1-4939-1878-2_8 |
0.517 |
|
| 2014 |
Ng DT, Sarkar CA. NP-Sticky: a web server for optimizing DNA ligation with non-palindromic sticky ends. Journal of Molecular Biology. 426: 1861-9. PMID 24518657 DOI: 10.1016/J.Jmb.2014.02.003 |
0.707 |
|
| 2014 |
Mehta HM, Futami M, Glaubach T, Lee DW, Andolina JR, Yang Q, Whichard Z, Quinn M, Lu HF, Kao WM, Przychodzen B, Sarkar CA, Minella A, Maciejewski JP, Corey SJ. Alternatively spliced, truncated GCSF receptor promotes leukemogenic properties and sensitivity to JAK inhibition. Leukemia. 28: 1041-51. PMID 24170028 DOI: 10.1038/Leu.2013.321 |
0.322 |
|
| 2013 |
Sarkar CA. Cell signaling. Concentrating (on) native proteins to control cell fate. Science (New York, N.Y.). 341: 1349-51. PMID 24052296 DOI: 10.1126/Science.1243994 |
0.373 |
|
| 2013 |
Barendt PA, Shah NA, Barendt GA, Kothari PA, Sarkar CA. Evidence for context-dependent complementarity of non-Shine-Dalgarno ribosome binding sites to Escherichia coli rRNA. Acs Chemical Biology. 8: 958-66. PMID 23427812 DOI: 10.1021/Cb3005726 |
0.722 |
|
| 2013 |
Barendt PA, Ng DT, McQuade CN, Sarkar CA. Streamlined protocol for mRNA display. Acs Combinatorial Science. 15: 77-81. PMID 23305392 DOI: 10.1021/Co300135R |
0.689 |
|
| 2013 |
Ng DT, Sarkar CA. Engineering signal peptides for enhanced protein secretion from Lactococcus lactis. Applied and Environmental Microbiology. 79: 347-56. PMID 23124224 DOI: 10.1128/Aem.02667-12 |
0.739 |
|
| 2013 |
Jung ST, Kelton W, Kang TH, Ng DT, Andersen JT, Sandlie I, Sarkar CA, Georgiou G. Effective phagocytosis of low Her2 tumor cell lines with engineered, aglycosylated IgG displaying high FcγRIIa affinity and selectivity. Acs Chemical Biology. 8: 368-75. PMID 23030766 DOI: 10.1021/Cb300455F |
0.714 |
|
| 2012 |
Palani S, Sarkar CA. Transient noise amplification and gene expression synchronization in a bistable mammalian cell-fate switch. Cell Reports. 1: 215-24. PMID 22832195 DOI: 10.1016/J.Celrep.2012.01.007 |
0.598 |
|
| 2012 |
Ng DT, Sarkar CA. Model-guided ligation strategy for optimal assembly of DNA libraries. Protein Engineering, Design & Selection : Peds. 25: 669-78. PMID 22543356 DOI: 10.1093/Protein/Gzs019 |
0.718 |
|
| 2012 |
Barendt PA, Shah NA, Barendt GA, Sarkar CA. Broad-specificity mRNA-rRNA complementarity in efficient protein translation. Plos Genetics. 8: e1002598. PMID 22457640 DOI: 10.1371/Journal.Pgen.1002598 |
0.725 |
|
| 2012 |
O'Shaughnessy EC, Sarkar CA. Analyzing and engineering cell signaling modules with synthetic biology. Current Opinion in Biotechnology. 23: 785-90. PMID 22325791 DOI: 10.1016/J.Copbio.2012.01.004 |
0.75 |
|
| 2011 |
Shah NA, Sarkar CA. Robust network topologies for generating switch-like cellular responses. Plos Computational Biology. 7: e1002085. PMID 21731481 DOI: 10.1371/Journal.Pcbi.1002085 |
0.529 |
|
| 2011 |
Palani S, Sarkar CA. Synthetic conversion of a graded receptor signal into a tunable, reversible switch. Molecular Systems Biology. 7: 480. PMID 21451590 DOI: 10.1038/Msb.2011.13 |
0.61 |
|
| 2011 |
Ng DT, Sarkar CA. Nisin-inducible secretion of a biologically active single-chain insulin analog by Lactococcus lactis NZ9000. Biotechnology and Bioengineering. 108: 1987-96. PMID 21391210 DOI: 10.1002/Bit.23130 |
0.708 |
|
| 2011 |
O'Shaughnessy EC, Palani S, Collins JJ, Sarkar CA. Tunable signal processing in synthetic MAP kinase cascades. Cell. 144: 119-31. PMID 21215374 DOI: 10.1016/J.Cell.2010.12.014 |
0.725 |
|
| 2010 |
Zahnd C, Sarkar CA, Plückthun A. Computational analysis of off-rate selection experiments to optimize affinity maturation by directed evolution. Protein Engineering, Design & Selection : Peds. 23: 175-84. PMID 20130104 DOI: 10.1093/Protein/Gzp087 |
0.332 |
|
| 2010 |
Whichard ZL, Sarkar CA, Kimmel M, Corey SJ. Hematopoiesis and its disorders: a systems biology approach. Blood. 115: 2339-47. PMID 20103779 DOI: 10.1182/Blood-2009-08-215798 |
0.311 |
|
| 2009 |
Palani S, Sarkar CA. Integrating extrinsic and intrinsic cues into a minimal model of lineage commitment for hematopoietic progenitors. Plos Computational Biology. 5: e1000518. PMID 19911036 DOI: 10.1371/Journal.Pcbi.1000518 |
0.599 |
|
| 2009 |
Milovnik P, Ferrari D, Sarkar CA, Plückthun A. Selection and characterization of DARPins specific for the neurotensin receptor 1. Protein Engineering, Design & Selection : Peds. 22: 357-66. PMID 19389717 DOI: 10.1093/Protein/Gzp011 |
0.36 |
|
| 2008 |
Sarkar CA, Dodevski I, Kenig M, Dudli S, Mohr A, Hermans E, Plückthun A. Directed evolution of a G protein-coupled receptor for expression, stability, and binding selectivity. Proceedings of the National Academy of Sciences of the United States of America. 105: 14808-13. PMID 18812512 DOI: 10.1073/Pnas.0803103105 |
0.391 |
|
| 2008 |
Palani S, Sarkar CA. Positive receptor feedback during lineage commitment can generate ultrasensitivity to ligand and confer robustness to a bistable switch. Biophysical Journal. 95: 1575-89. PMID 18469073 DOI: 10.1529/Biophysj.107.120600 |
0.613 |
|
| 2005 |
Kubetzko S, Sarkar CA, Plückthun A. Protein PEGylation decreases observed target association rates via a dual blocking mechanism. Molecular Pharmacology. 68: 1439-54. PMID 16099846 DOI: 10.1124/Mol.105.014910 |
0.354 |
|
| 2003 |
Sarkar CA, Lowenhaupt K, Wang PJ, Horan T, Lauffenburger DA. Parsing the effects of binding, signaling, and trafficking on the mitogenic potencies of granulocyte colony-stimulating factor analogues. Biotechnology Progress. 19: 955-64. PMID 12790662 DOI: 10.1021/Bp020017G |
0.539 |
|
| 2003 |
Ricci MS, Sarkar CA, Fallon EM, Lauffenburger DA, Brems DN. pH Dependence of structural stability of interleukin-2 and granulocyte colony-stimulating factor. Protein Science : a Publication of the Protein Society. 12: 1030-8. PMID 12717025 DOI: 10.1110/Ps.0230103 |
0.455 |
|
| 2003 |
Sarkar CA, Lauffenburger DA. Cell-level pharmacokinetic model of granulocyte colony-stimulating factor: implications for ligand lifetime and potency in vivo. Molecular Pharmacology. 63: 147-58. PMID 12488547 DOI: 10.1124/Mol.63.1.147 |
0.491 |
|
| 2002 |
Sarkar CA, Lowenhaupt K, Horan T, Boone TC, Tidor B, Lauffenburger DA. Rational cytokine design for increased lifetime and enhanced potency using pH-activated "histidine switching" Nature Biotechnology. 20: 908-913. PMID 12161759 DOI: 10.1038/Nbt725 |
0.513 |
|
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