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Shailja Pathania, Ph.D. - Publications

Affiliations: 
2002 University of Texas at Austin, Austin, Texas, U.S.A. 
Area:
Molecular Biology, Microbiology Biology
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28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Duan H, Pathania S. RPA, RFWD3 and BRCA2 at stalled forks: a balancing act. Molecular & Cellular Oncology. 7: 1801089. PMID 33241105 DOI: 10.1080/23723556.2020.1801089  0.4
2020 Duan H, Mansour S, Reed R, Gillis MK, Parent B, Liu B, Sztupinszki Z, Birkbak N, Szallasi Z, Elia AEH, Garber JE, Pathania S. E3 ligase RFWD3 is a novel modulator of stalled fork stability in BRCA2-deficient cells. The Journal of Cell Biology. 219. PMID 32391871 DOI: 10.1083/Jcb.201908192  0.362
2020 Rivera J, Khalid D, Tran S, Kibaja K, Pathania S. Abstract B36: Tracking the path of breast tumorigenesis in BRCA1 mutant breast cancer Cancer Research. 80. DOI: 10.1158/1538-7445.Camodels2020-B36  0.312
2019 Maertens O, Kuzmickas R, Manchester HE, Emerson CE, Gavin AG, Guild CJ, Wong TC, De Raedt T, Bowman-Colin C, Hatchi E, Garraway LA, Flaherty KT, Pathania S, Elledge SJ, Cichowski K. MAPK pathway suppression unmasks latent DNA repair defects and confers a chemical synthetic vulnerability in BRAF, NRAS, and NF1 mutant melanomas. Cancer Discovery. PMID 30709805 DOI: 10.1158/2159-8290.Cd-18-0879  0.409
2019 Maertens O, Kuzmickas R, Manchester H, Emerson C, Gavin A, Guild C, Wong T, Raedt TD, Bowman-Colin C, Hatchi E, Garraway L, Flaherty K, Pathania S, Elledge S, Cichowski K. Abstract LB-113: MAPK pathway suppression unmasks latent DNA repair defects and confers a chemical synthetic vulnerability inBRAF,NRASandNF1-mutant melanomas Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-Lb-113  0.432
2019 Iyer S, Zhang S, Farkkila A, Smith S, Pepin D, Mohan R, Reinhardt F, Xia T, Chavarria TE, Hoefsmit E, Pathania S, Zhou Y, Elias KM, Neel BG, Weinberg RA. Abstract PR04: The genomic architecture of serous carcinomas shapes the tumor microenvironment and modulates responses to targeted and immunotherapies Molecular Cancer Therapeutics. 18. DOI: 10.1158/1535-7163.Targ-19-Pr04  0.424
2018 Birkbak NJ, Li Y, Pathania S, Greene-Colozzi A, Dreze M, Bowman-Colin C, Sztupinszki Z, Krzystanek M, Diossy M, Tung N, Ryan PD, Garber JE, Silver DP, Iglehart JD, Wang ZC, et al. Overexpression of BLM promotes DNA damage and increased sensitivity to platinum salts in triple negative breast and serous ovarian cancers. Annals of Oncology : Official Journal of the European Society For Medical Oncology. PMID 29452344 DOI: 10.1093/Annonc/Mdy049  0.326
2017 Duan H, Reed R, Garber J, Pathania S. Abstract PR05: Distinct BRCA1- and BRCA2-specific functions at stalled replication forks: Clinical implications for differences between BRCA1 and BRCA2 mutation-driven cancer Molecular Cancer Research. 15. DOI: 10.1158/1557-3125.Dnarepair16-Pr05  0.425
2017 Pathania S, Reed R, Duan H, Culhane A, Garber J. Abstract P5-06-04: Distinct BRCA1 and BRCA2 specific functions at stalled replication forks - Clinical implications for differences between BRCA1 and BRCA2 mutation driven cancer Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P5-06-04  0.341
2016 Wang H, Bierie B, Li AG, Pathania S, Toomire K, Dimitrov SD, Liu B, Gelman R, Giobbie-Hurder A, Feunteun J, Polyak K, Livingston DM. BRCA1/FANCD2/BRG1-Driven DNA Repair Stabilizes the Differentiation State of Human Mammary Epithelial Cells. Molecular Cell. PMID 27373334 DOI: 10.1016/J.Molcel.2016.05.038  0.455
2016 Pathania S, Reed R, Duan H, Culhane A, Garber J. Abstract LB-162: BRCA2, and not BRCA1, dependent crosstalk between replication stress suppression and nucleotide excision repair - Clinical implications Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-162  0.424
2015 Hatchi E, Skourti-Stathaki K, Ventz S, Pinello L, Yen A, Kamieniarz-Gdula K, Dimitrov S, Pathania S, McKinney KM, Eaton ML, Kellis M, Hill SJ, Parmigiani G, Proudfoot NJ, Livingston DM. BRCA1 recruitment to transcriptional pause sites is required for R-loop-driven DNA damage repair. Molecular Cell. 57: 636-47. PMID 25699710 DOI: 10.1016/J.Molcel.2015.01.011  0.476
2015 Pathania S, Bade S, Guillou ML, Burke K, Su Y, Ting DT, Polyak K, Richardson AL, Feunteun J, Garber JE, Livingston DM. Abstract S5-05: Defective stalled replication fork repair and predisposition to hereditary breast cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-S5-05  0.399
2014 Pathania S, Bade S, Le Guillou M, Burke K, Reed R, Bowman-Colin C, Su Y, Ting DT, Polyak K, Richardson AL, Feunteun J, Garber JE, Livingston DM. BRCA1 haploinsufficiency for replication stress suppression in primary cells. Nature Communications. 5: 5496. PMID 25400221 DOI: 10.1038/Ncomms6496  0.376
2014 Nicolo AD, Giobbie-Hurder A, Pathania S, Parisini E, Gelman RS, Ladias JAA, Joukov V. 492Pdfunctional Analysis Of The Brca1 H1686Q Sequence Variant: From Biology To Clinic Annals of Oncology. 25. DOI: 10.1093/Annonc/Mdu332.2  0.448
2013 Dimitrov SD, Lu D, Naetar N, Hu Y, Pathania S, Kanellopoulou C, Livingston DM. Physiological modulation of endogenous BRCA1 p220 abundance suppresses DNA damage during the cell cycle. Genes & Development. 27: 2274-91. PMID 24142877 DOI: 10.1101/Gad.225045.113  0.383
2012 Nicolo AD, Pathania S, Parisini E, Joukov V. Abstract P4-10-01: Edgetic perturbation of BRCT-mediated interactions caused by the BRCA1 H1686Q sequence variant Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P4-10-01  0.375
2011 Pathania S, Nguyen J, Hill SJ, Scully R, Adelmant GO, Marto JA, Feunteun J, Livingston DM. BRCA1 is required for postreplication repair after UV-induced DNA damage. Molecular Cell. 44: 235-51. PMID 21963239 DOI: 10.1016/J.Molcel.2011.09.002  0.477
2009 Johnson N, Cai D, Kennedy RD, Pathania S, Arora M, Li YC, D'Andrea AD, Parvin JD, Shapiro GI. Cdk1 participates in BRCA1-dependent S phase checkpoint control in response to DNA damage. Molecular Cell. 35: 327-39. PMID 19683496 DOI: 10.1016/J.Molcel.2009.06.036  0.439
2006 Greenberg RA, Sobhian B, Pathania S, Cantor SB, Nakatani Y, Livingston DM. Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes. Genes & Development. 20: 34-46. PMID 16391231 DOI: 10.1101/Gad.1381306  0.47
2005 Yin Z, Jayaram M, Pathania S, Harshey RM. The Mu transposase interwraps distant DNA sites within a functional transpososome in the absence of DNA supercoiling. The Journal of Biological Chemistry. 280: 6149-56. PMID 15563455 DOI: 10.1074/Jbc.M411679200  0.655
2004 Au TK, Pathania S, Harshey RM. True reversal of Mu integration. The Embo Journal. 23: 3408-20. PMID 15282550 DOI: 10.1038/Sj.Emboj.7600344  0.541
2003 Pathania S, Jayaram M, Harshey RM. A unique right end-enhancer complex precedes synapsis of Mu ends: the enhancer is sequestered within the transpososome throughout transposition. The Embo Journal. 22: 3725-36. PMID 12853487 DOI: 10.1093/Emboj/Cdg354  0.637
2002 Grainge I, Pathania S, Vologodskii A, Harshey RM, Jayaram M. Symmetric DNA sites are functionally asymmetric within Flp and Cre site-specific DNA recombination synapses. Journal of Molecular Biology. 320: 515-27. PMID 12096907 DOI: 10.1016/S0022-2836(02)00517-X  0.619
2002 Pathania S, Jayaram M, Harshey RM. Path of DNA within the Mu transpososome. Transposase interactions bridging two Mu ends and the enhancer trap five DNA supercoils. Cell. 109: 425-36. PMID 12086600 DOI: 10.1016/S0092-8674(02)00728-6  0.66
1999 Voziyanov Y, Pathania S, Jayaram M. A general model for site-specific recombination by the integrase family recombinases. Nucleic Acids Research. 27: 930-41. PMID 9927723 DOI: 10.1093/Nar/27.4.930  0.387
1998 Xu CJ, Ahn YT, Pathania S, Jayaram M. Flp ribonuclease activities. Mechanistic similarities and contrasts to site-specific DNA recombination. The Journal of Biological Chemistry. 273: 30591-8. PMID 9804830 DOI: 10.1074/Jbc.273.46.30591  0.35
1998 Lee J, Voziyanov Y, Pathania S, Jayaram M. Structural alterations and conformational dynamics in Holliday junctions induced by binding of a site-specific recombinase. Molecular Cell. 1: 483-93. PMID 9660933 DOI: 10.1016/S1097-2765(00)80049-0  0.343
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