Year |
Citation |
Score |
2023 |
Sugawara S, Hueber B, Woolley G, Terry K, Kroll K, Manickam C, Ram DR, Ndhlovu LC, Goepfert P, Jost S, Reeves RK. Multiplex interrogation of the NK cell signalome reveals global downregulation of CD16 signaling during lentivirus infection through an IL-18/ADAM17-dependent mechanism. Plos Pathogens. 19: e1011629. PMID 37669308 DOI: 10.1371/journal.ppat.1011629 |
0.393 |
|
2023 |
Rascle P, Woolley G, Jost S, Manickam C, Reeves RK. NK cell education: Physiological and pathological influences. Frontiers in Immunology. 14: 1087155. PMID 36742337 DOI: 10.3389/fimmu.2023.1087155 |
0.313 |
|
2022 |
Woolley G, Mosher M, Kroll K, Jones R, Hueber B, Sugawara S, Manickam C, Terry K, Varner V, Lifton M, Ram D, Fennessey CM, Keele BF, Reeves RK. Natural Killer Cells Regulate Acute SIV Replication, Dissemination, and Inflammation, but Do Not Impact Independent Transmission Events. Journal of Virology. e0151922. PMID 36511699 DOI: 10.1128/jvi.01519-22 |
0.456 |
|
2022 |
Cooper A, Sidaway A, Chandrashekar A, Latta E, Chakraborty K, Yu J, McMahan K, Giffin V, Manickam C, Kroll K, Mosher M, Reeves RK, Gam R, Arthofer E, Choudhry M, et al. A genetically engineered, stem-cell-derived cellular vaccine. Cell Reports. Medicine. 100843. PMID 36480934 DOI: 10.1016/j.xcrm.2022.100843 |
0.424 |
|
2021 |
Jones R, Kroll K, Broedlow C, Schifanella L, Smith S, Hueber B, Shah SV, Ram DR, Manickam C, Varner V, Klatt NR, Reeves RK. Probiotic supplementation reduces inflammatory profiles but does not prevent oral immune perturbations during SIV infection. Scientific Reports. 11: 14507. PMID 34267278 DOI: 10.1038/s41598-021-93918-x |
0.371 |
|
2020 |
Sugawara S, Manickam C, Reeves RK. TRIGGERED: could refocused cell signaling be key to NK cell-based HIV immunotherapeutics? Aids (London, England). PMID 33116071 DOI: 10.1097/QAD.0000000000002743 |
0.427 |
|
2020 |
Ram DR, Arias CF, Kroll K, Hueber B, Manickam C, Jones RA, Smith ST, Shah SV, Varner VH, Reeves RK. Characterization of Rhesus Macaque Liver-Resident CD49a NK Cells During Retrovirus Infections. Frontiers in Immunology. 11: 1676. PMID 32849583 DOI: 10.3389/Fimmu.2020.01676 |
0.505 |
|
2020 |
Manickam C, Sugawara S, Reeves RK. Friends or foes? The knowns and unknowns of natural killer cell biology in COVID-19 and other coronaviruses in July 2020. Plos Pathogens. 16: e1008820. PMID 32845937 DOI: 10.1371/Journal.Ppat.1008820 |
0.531 |
|
2019 |
Manickam C, Shah SV, Nohara J, Ferrari G, Reeves RK. Monkeying Around: Using Non-human Primate Models to Study NK Cell Biology in HIV Infections. Frontiers in Immunology. 10: 1124. PMID 31191520 DOI: 10.3389/Fimmu.2019.01124 |
0.526 |
|
2019 |
Ram DR, Manickam C, Lucar O, Shah SV, Reeves RK. Adaptive NK cell responses in HIV/SIV infections: A roadmap to cell-based therapeutics? Journal of Leukocyte Biology. PMID 30730588 DOI: 10.1002/Jlb.Mr0718-303R |
0.546 |
|
2018 |
Manickam C, Shah SV, Lucar O, Ram DR, Reeves RK. Cytokine-Mediated Tissue Injury in Non-human Primate Models of Viral Infections. Frontiers in Immunology. 9: 2862. PMID 30568659 DOI: 10.3389/Fimmu.2018.02862 |
0.512 |
|
2018 |
Shah SV, Manickam C, Ram DR, Kroll K, Itell H, Permar SR, Barouch DH, Klatt NR, Reeves RK. CMV Primes Functional Alternative Signaling in Adaptive Δg NK Cells but Is Subverted by Lentivirus Infection in Rhesus Macaques. Cell Reports. 25: 2766-2774.e3. PMID 30517864 DOI: 10.1016/J.Celrep.2018.11.020 |
0.486 |
|
2018 |
Manickam C, Li H, Shah SV, Kroll K, Reeves RK. Non-linear multidimensional flow cytometry analyses delineate NK cell phenotypes in normal and HIV-infected chimpanzees. International Immunology. PMID 30418531 DOI: 10.1093/Intimm/Dxy076 |
0.512 |
|
2018 |
Ram DR, Manickam C, Hueber B, Itell HL, Permar SR, Varner V, Reeves RK. Tracking KLRC2 (NKG2C)+ memory-like NK cells in SIV+ and rhCMV+ rhesus macaques. Plos Pathogens. 14: e1007104. PMID 29851983 DOI: 10.1371/Journal.Ppat.1007104 |
0.468 |
|
2018 |
Chettimada S, Lorenz DR, Misra V, Dillon ST, Reeves RK, Manickam C, Morgello S, Kirk GD, Mehta SH, Gabuzda D. Exosome markers associated with immune activation and oxidative stress in HIV patients on antiretroviral therapy. Scientific Reports. 8: 7227. PMID 29740045 DOI: 10.1038/S41598-018-25515-4 |
0.341 |
|
2018 |
Manickam C, Nwanze C, Ram DR, Shah SV, Smith S, Jones R, Hueber B, Kroll K, Varner V, Goepfert P, Jost S, Reeves RK. Progressive lentivirus infection induces natural killer cell receptor-expressing B cells in the gastrointestinal tract. Aids (London, England). PMID 29734222 DOI: 10.1097/Qad.0000000000001855 |
0.496 |
|
2017 |
Shah SV, Manickam C, Ram DR, Reeves RK. Innate Lymphoid Cells in HIV/SIV Infections. Frontiers in Immunology. 8: 1818. PMID 29326704 DOI: 10.3389/Fimmu.2017.01818 |
0.496 |
|
2017 |
Manickam C, Martinot AJ, Jones RA, Varner V, Reeves RK. Hepatic immunopathology during occult hepacivirus re-infection. Virology. 512: 48-55. PMID 28915405 DOI: 10.1016/J.Virol.2017.08.037 |
0.483 |
|
2017 |
Manickam C, Wachtman L, Martinot AJ, Giavedoni LD, Reeves RK. Metabolic Dysregulation in Hepacivirus Infection of Common Marmosets (Callithrix jacchus). Plos One. 12: e0170240. PMID 28085952 DOI: 10.1371/Journal.Pone.0170240 |
0.386 |
|
2016 |
Manickam C, Rajakumar P, Wachtman L, Kramer JA, Martinot AJ, Varner V, Giavedoni LD, Reeves RK. Acute liver damage associated with innate immune activation in a small nonhuman primate model of Hepacivirus infection. Journal of Virology. PMID 27489267 DOI: 10.1128/Jvi.01051-16 |
0.492 |
|
2016 |
Dwivedi V, Manickam C, Dhakal S, Binjawadagi B, Ouyang K, Hiremath J, Khatri M, Hague JG, Lee CW, Renukaradhya GJ. Adjuvant effects of invariant NKT cell ligand potentiates the innate and adaptive immunity to an inactivated H1N1 swine influenza virus vaccine in pigs. Veterinary Microbiology. 186: 157-163. PMID 27016770 DOI: 10.1016/J.Vetmic.2016.02.028 |
0.523 |
|
2016 |
Dwivedi V, Manickam C, Dhakal S, Binjawadagi B, Ouyang K, Hiremath J, Khatri M, Hague JG, Lee CW, Renukaradhya GJ. Adjuvant effects of invariant NKT cell ligand potentiates the innate and adaptive immunity to an inactivated H1N1 swine influenza virus vaccine in pigs Veterinary Microbiology. 186: 157-163. DOI: 10.1016/j.vetmic.2016.02.028 |
0.385 |
|
2015 |
Reeves RK, Li H, Jost S, Blass E, Li H, Schafer JL, Varner V, Manickam C, Eslamizar L, Altfeld M, von Andrian UH, Barouch DH. Antigen-specific NK cell memory in rhesus macaques. Nature Immunology. PMID 26193080 DOI: 10.1038/Ni.3227 |
0.541 |
|
2014 |
Manickam C, Reeves RK. Modeling HCV disease in animals: virology, immunology and pathogenesis of HCV and GBV-B infections. Frontiers in Microbiology. 5: 690. PMID 25538700 DOI: 10.3389/Fmicb.2014.00690 |
0.438 |
|
2014 |
Binjawadagi B, Dwivedi V, Manickam C, Ouyang K, Torrelles JB, Renukaradhya GJ. An innovative approach to induce cross-protective immunity against porcine reproductive and respiratory syndrome virus in the lungs of pigs through adjuvanted nanotechnology-based vaccination. International Journal of Nanomedicine. 9: 1519-35. PMID 24711701 DOI: 10.2147/Ijn.S59924 |
0.485 |
|
2014 |
Ouyang K, Woodiga SA, Dwivedi V, Buckwalter CM, Singh AK, Binjawadagi B, Hiremath J, Manickam C, Schleappi R, Khatri M, Wu J, King SJ, Renukaradhya GJ. Pretreatment of epithelial cells with live Streptococcus pneumoniae has no detectable effect on influenza A virus replication in vitro. Plos One. 9: e90066. PMID 24594847 DOI: 10.1371/Journal.Pone.0090066 |
0.474 |
|
2014 |
Binjawadagi B, Dwivedi V, Manickam C, Ouyang K, Wu Y, Lee LJ, Torrelles JB, Renukaradhya GJ. Adjuvanted poly(lactic-co-glycolic) acid nanoparticle-entrapped inactivated porcine reproductive and respiratory syndrome virus vaccine elicits cross-protective immune response in pigs. International Journal of Nanomedicine. 9: 679-94. PMID 24493925 DOI: 10.2147/IJN.S56127 |
0.415 |
|
2013 |
Dwivedi V, Manickam C, Binjawadagi B, Renukaradhya GJ. PLGA nanoparticle entrapped killed porcine reproductive and respiratory syndrome virus vaccine helps in viral clearance in pigs. Veterinary Microbiology. 166: 47-58. PMID 23764272 DOI: 10.1016/J.Vetmic.2013.04.029 |
0.49 |
|
2013 |
Manickam C, Dwivedi V, Miller J, Papenfuss T, Renukaradhya GJ. Mycobacterium tuberculosis whole cell lysate enhances proliferation of CD8 positive lymphocytes and nitric oxide secretion in the lungs of live porcine respiratory and reproductive syndrome virus vaccinated pigs. Viral Immunology. 26: 102-8. PMID 23308386 DOI: 10.1089/Vim.2012.0065 |
0.468 |
|
2013 |
Manickam C, Dwivedi V, Patterson R, Papenfuss T, Renukaradhya GJ. Porcine reproductive and respiratory syndrome virus induces pronounced immune modulatory responses at mucosal tissues in the parental vaccine strain VR2332 infected pigs. Veterinary Microbiology. 162: 68-77. PMID 22995873 DOI: 10.1016/J.Vetmic.2012.08.021 |
0.555 |
|
2012 |
Dwivedi V, Manickam C, Binjawadagi B, Joyappa D, Renukaradhya GJ. Biodegradable nanoparticle-entrapped vaccine induces cross-protective immune response against a virulent heterologous respiratory viral infection in pigs. Plos One. 7: e51794. PMID 23240064 DOI: 10.1371/Journal.Pone.0051794 |
0.492 |
|
2012 |
Renukaradhya GJ, Dwivedi V, Manickam C, Binjawadagi B, Benfield D. Mucosal vaccines to prevent porcine reproductive and respiratory syndrome: a new perspective. Animal Health Research Reviews / Conference of Research Workers in Animal Diseases. 13: 21-37. PMID 22717576 DOI: 10.1017/S1466252312000023 |
0.484 |
|
2012 |
Dwivedi V, Manickam C, Binjawadagi B, Linhares D, Murtaugh MP, Renukaradhya GJ. Evaluation of immune responses to porcine reproductive and respiratory syndrome virus in pigs during early stage of infection under farm conditions. Virology Journal. 9: 45. PMID 22340040 DOI: 10.1186/1743-422X-9-45 |
0.575 |
|
2011 |
Binjawadagi B, Dwivedi V, Manickam C, Torrelles JB, Renukaradhya GJ. Intranasal delivery of an adjuvanted modified live porcine reproductive and respiratory syndrome virus vaccine reduces ROS production. Viral Immunology. 24: 475-82. PMID 22111597 DOI: 10.1089/Vim.2011.0040 |
0.525 |
|
2011 |
Dwivedi V, Manickam C, Patterson R, Dodson K, Weeman M, Renukaradhya GJ. Intranasal delivery of whole cell lysate of Mycobacterium tuberculosis induces protective immune responses to a modified live porcine reproductive and respiratory syndrome virus vaccine in pigs. Vaccine. 29: 4067-76. PMID 21419164 DOI: 10.1016/J.Vaccine.2011.03.005 |
0.541 |
|
2011 |
Dwivedi V, Manickam C, Patterson R, Dodson K, Murtaugh M, Torrelles JB, Schlesinger LS, Renukaradhya GJ. Cross-protective immunity to porcine reproductive and respiratory syndrome virus by intranasal delivery of a live virus vaccine with a potent adjuvant. Vaccine. 29: 4058-66. PMID 21419162 DOI: 10.1016/J.Vaccine.2011.03.006 |
0.541 |
|
2011 |
Renukaradhya GJ, Manickam C, Khatri M, Rauf A, Li X, Tsuji M, Rajashekara G, Dwivedi V. Functional invariant NKT cells in pig lungs regulate the airway hyperreactivity: a potential animal model. Journal of Clinical Immunology. 31: 228-39. PMID 21042929 DOI: 10.1007/S10875-010-9476-4 |
0.421 |
|
2010 |
Khatri M, Dwivedi V, Krakowka S, Manickam C, Ali A, Wang L, Qin Z, Renukaradhya GJ, Lee CW. Swine influenza H1N1 virus induces acute inflammatory immune responses in pig lungs: a potential animal model for human H1N1 influenza virus. Journal of Virology. 84: 11210-8. PMID 20719941 DOI: 10.1128/Jvi.01211-10 |
0.462 |
|
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