Chris P. Ponting - Publications

Affiliations: 
MRC Functional Genomics Unit University of Oxford, Oxford, United Kingdom 
Website:
http://www.mrcfgu.ox.ac.uk/research/chris-p-ponting

216 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Sirey TM, Ponting CP. Insights into the post-transcriptional regulation of the mitochondrial electron transport chain. Biochemical Society Transactions. 44: 1491-1498. PMID 27911731 DOI: 10.1042/BST20160100  0.32
2016 Chan MC, Ilott NE, Schödel J, Sims D, Tumber A, Lippl K, Mole DR, Pugh CW, Ratcliffe PJ, Ponting CP, Schofield CJ. Tuning the transcriptional response to hypoxia by inhibiting HIF prolyl- and asparaginyl-hydroxylases. The Journal of Biological Chemistry. PMID 27502280 DOI: 10.1074/jbc.M116.749291  0.92
2016 Fenwick AL, Kliszczak M, Cooper F, Murray J, Sanchez-Pulido L, Twigg SR, Goriely A, McGowan SJ, Miller KA, Taylor IB, Logan C, Bozdogan S, Danda S, Dixon J, ... ... Ponting CP, et al. Mutations in CDC45, Encoding an Essential Component of the Pre-initiation Complex, Cause Meier-Gorlin Syndrome and Craniosynostosis. American Journal of Human Genetics. PMID 27374770 DOI: 10.1016/j.ajhg.2016.05.019  0.92
2016 Angermueller C, Clark SJ, Lee HJ, Macaulay IC, Teng MJ, Hu TX, Krueger F, Smallwood SA, Ponting CP, Voet T, Kelsey G, Stegle O, Reik W. Parallel single-cell sequencing links transcriptional and epigenetic heterogeneity. Nature Methods. PMID 26752769 DOI: 10.1038/nmeth.3728  0.92
2015 Pembroke WG, Babbs A, Davies K, Ponting CP, Oliver PL. Temporal transcriptomics suggest that twin-peaking genes reset the clock. Elife. 4. PMID 26523393 DOI: 10.7554/eLife.10518  0.92
2015 Chung G, Rose AM, Petalcorin MI, Martin JS, Kessler Z, Sanchez-Pulido L, Ponting CP, Yanowitz JL, Boulton SJ. REC-1 and HIM-5 distribute meiotic crossovers and function redundantly in meiotic double-strand break formation in Caenorhabditis elegans. Genes & Development. 29: 1969-79. PMID 26385965 DOI: 10.1101/gad.266056.115  0.92
2015 Tan JY, Sirey T, Honti F, Graham B, Piovesan A, Merkenschlager M, Webber C, Ponting CP, Marques AC. Corrigendum: Extensive microRNA-mediated crosstalk between lncRNAs and mRNAs in mouse embryonic stem cells. Genome Research. 25: 1410.1. PMID 26330573 DOI: 25/9/1410.1  0.32
2015 Wilson NK, Kent DG, Buettner F, Shehata M, Macaulay IC, Calero-Nieto FJ, Sánchez Castillo M, Oedekoven CA, Diamanti E, Schulte R, Ponting CP, Voet T, Caldas C, Stingl J, Green AR, et al. Combined Single-Cell Functional and Gene Expression Analysis Resolves Heterogeneity within Stem Cell Populations. Cell Stem Cell. 16: 712-24. PMID 26004780 DOI: 10.1016/j.stem.2015.04.004  0.92
2015 Wehrspaun CC, Haerty W, Ponting CP. Microglia recapitulate a hematopoietic master regulator network in the aging human frontal cortex. Neurobiology of Aging. 36: 2443.e9-2443.e20. PMID 26002684 DOI: 10.1016/j.neurobiolaging.2015.04.008  0.92
2015 Sims D, Ponting CP, Heger A. CGAT: a model for immersive personalized training in computational genomics. Briefings in Functional Genomics. PMID 25981124 DOI: 10.1093/bfgp/elv021  0.92
2015 Macaulay IC, Haerty W, Kumar P, Li YI, Hu TX, Teng MJ, Goolam M, Saurat N, Coupland P, Shirley LM, Smith M, Van der Aa N, Banerjee R, Ellis PD, Quail MA, ... ... Ponting CP, et al. G&T-seq: parallel sequencing of single-cell genomes and transcriptomes. Nature Methods. 12: 519-22. PMID 25915121 DOI: 10.1038/nmeth.3370  0.92
2015 Tan JY, Sirey T, Honti F, Graham B, Piovesan A, Merkenschlager M, Webber C, Ponting CP, Marques AC. Extensive microRNA-mediated crosstalk between lncRNAs and mRNAs in mouse embryonic stem cells. Genome Research. 25: 655-66. PMID 25792609 DOI: 10.1101/gr.181974.114  0.92
2015 Wassif CA, Cross JL, Iben J, Sanchez-Pulido L, Cougnoux A, Platt FM, Ory DS, Ponting CP, Bailey-Wilson JE, Biesecker LG, Porter FD. High incidence of unrecognized visceral/neurological late-onset Niemann-Pick disease, type C1, predicted by analysis of massively parallel sequencing data sets. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 25764212 DOI: 10.1038/gim.2015.25  0.92
2015 Tan JY, Vance KW, Varela MA, Sirey T, Watson LM, Curtis HJ, Marinello M, Alves S, Steinkraus BR, Cooper S, Nesterova T, Brockdorff N, Fulga TA, Brice A, Sittler A, ... ... Ponting CP, et al. Corrigendum: Cross-talking noncoding RNAs contribute to cell-specific neurodegeneration in SCA7. Nature Structural & Molecular Biology. 22: 272. PMID 25736092 DOI: 10.1038/nsmb0315-272b  0.32
2015 Haerty W, Ponting CP. Unexpected selection to retain high GC content and splicing enhancers within exons of multiexonic lncRNA loci. Rna (New York, N.Y.). 21: 333-46. PMID 25589248 DOI: 10.1261/rna.047324.114  0.92
2015 Li YI, Sanchez-Pulido L, Haerty W, Ponting CP. RBFOX and PTBP1 proteins regulate the alternative splicing of micro-exons in human brain transcripts. Genome Research. 25: 1-13. PMID 25524026 DOI: 10.1101/gr.181990.114  0.92
2015 Parkinson NJ, Roddis M, Ferneyhough B, Zhang G, Marsden AJ, Maslau S, Sanchez-Pearson Y, Barthlott T, Humphreys IR, Ladell K, Price DA, Ponting CP, Hollander G, Fischer MD. Violation of the 12/23 rule of genomic V(D)J recombination is common in lymphocytes. Genome Research. 25: 226-34. PMID 25367293 DOI: 10.1101/gr.179770.114  0.92
2014 Li C, Zhang Y, Li J, Kong L, Hu H, Pan H, Xu L, Deng Y, Li Q, Jin L, Yu H, Chen Y, Liu B, Yang L, Liu S, ... ... Ponting CP, et al. Two Antarctic penguin genomes reveal insights into their evolutionary history and molecular changes related to the Antarctic environment. Gigascience. 3: 27. PMID 25671092 DOI: 10.1186/2047-217X-3-27  0.92
2014 Sanchez-Pulido L, Ponting CP. TM6SF2 and MAC30, new enzyme homologs in sterol metabolism and common metabolic disease. Frontiers in Genetics. 5: 439. PMID 25566323 DOI: 10.3389/fgene.2014.00439  0.92
2014 Rajan P, Stockley J, Sudbery IM, Fleming JT, Hedley A, Kalna G, Sims D, Ponting CP, Heger A, Robson CN, McMenemin RM, Pedley ID, Leung HY. Identification of a candidate prognostic gene signature by transcriptome analysis of matched pre- and post-treatment prostatic biopsies from patients with advanced prostate cancer. Bmc Cancer. 14: 977. PMID 25519703 DOI: 10.1186/1471-2407-14-977  0.92
2014 Mannion NM, Greenwood SM, Young R, Cox S, Brindle J, Read D, Nellåker C, Vesely C, Ponting CP, McLaughlin PJ, Jantsch MF, Dorin J, Adams IR, Scadden AD, Ohman M, et al. The RNA-editing enzyme ADAR1 controls innate immune responses to RNA. Cell Reports. 9: 1482-94. PMID 25456137 DOI: 10.1016/j.celrep.2014.10.041  0.92
2014 Chalei V, Sansom SN, Kong L, Lee S, Montiel JF, Vance KW, Ponting CP. The long non-coding RNA Dali is an epigenetic regulator of neural differentiation. Elife. 3: e04530. PMID 25415054 DOI: 10.7554/eLife.04530  0.92
2014 Tan JY, Vance KW, Varela MA, Sirey T, Watson LM, Curtis HJ, Marinello M, Alves S, Steinkraus BR, Cooper S, Nesterova T, Brockdorff N, Fulga TA, Brice A, Sittler A, ... ... Ponting CP, et al. Cross-talking noncoding RNAs contribute to cell-specific neurodegeneration in SCA7. Nature Structural & Molecular Biology. 21: 955-61. PMID 25306109 DOI: 10.1038/nsmb.2902  0.92
2014 Sansom SN, Shikama-Dorn N, Zhanybekova S, Nusspaumer G, Macaulay IC, Deadman ME, Heger A, Ponting CP, Holländer GA. Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia. Genome Research. 24: 1918-31. PMID 25224068 DOI: 10.1101/gr.171645.113  0.92
2014 Oliver PL, Chodroff RA, Gosal A, Edwards B, Cheung AF, Gomez-Rodriguez J, Elliot G, Garrett LJ, Lickiss T, Szele F, Green ED, Molnár Z, Ponting CP. Disruption of Visc-2, a Brain-Expressed Conserved Long Noncoding RNA, Does Not Elicit an Overt Anatomical or Behavioral Phenotype. Cerebral Cortex (New York, N.Y. : 1991). PMID 25209608 DOI: 10.1093/cercor/bhu196  0.92
2014 Brawand D, Wagner CE, Li YI, Malinsky M, Keller I, Fan S, Simakov O, Ng AY, Lim ZW, Bezault E, Turner-Maier J, Johnson J, Alcazar R, Noh HJ, Russell P, ... ... Ponting CP, et al. The genomic substrate for adaptive radiation in African cichlid fish. Nature. 513: 375-81. PMID 25186727 DOI: 10.1038/nature13726  0.92
2014 Bassett AR, Azzam G, Wheatley L, Tibbit C, Rajakumar T, McGowan S, Stanger N, Ewels PA, Taylor S, Ponting CP, Liu JL, Sauka-Spengler T, Fulga TA. Understanding functional miRNA-target interactions in vivo by site-specific genome engineering. Nature Communications. 5: 4640. PMID 25135198 DOI: 10.1038/ncomms5640  0.92
2014 Bassett AR, Akhtar A, Barlow DP, Bird AP, Brockdorff N, Duboule D, Ephrussi A, Ferguson-Smith AC, Gingeras TR, Haerty W, Higgs DR, Miska EA, Ponting CP. Considerations when investigating lncRNA function in vivo. Elife. 3: e03058. PMID 25124674 DOI: 10.7554/eLife.03058  0.92
2014 White SA, Buscaino A, Sanchez-Pulido L, Ponting CP, Nowicki MW, Allshire RC. The RFTS domain of Raf2 is required for Cul4 interaction and heterochromatin integrity in fission yeast. Plos One. 9: e104161. PMID 25090107 DOI: 10.1371/journal.pone.0104161  0.92
2014 Rands CM, Meader S, Ponting CP, Lunter G. 8.2% of the Human genome is constrained: variation in rates of turnover across functional element classes in the human lineage. Plos Genetics. 10: e1004525. PMID 25057982 DOI: 10.1371/journal.pgen.1004525  0.92
2014 Vance KW, Ponting CP. Transcriptional regulatory functions of nuclear long noncoding RNAs. Trends in Genetics : Tig. 30: 348-55. PMID 24974018 DOI: 10.1016/j.tig.2014.06.001  0.92
2014 Ferry Q, Steinberg J, Webber C, FitzPatrick DR, Ponting CP, Zisserman A, Nellåker C. Diagnostically relevant facial gestalt information from ordinary photos. Elife. 3: e02020. PMID 24963138 DOI: 10.7554/eLife.02020.001  0.92
2014 Rainger J, Pehlivan D, Johansson S, Bengani H, Sanchez-Pulido L, Williamson KA, Ture M, Barker H, Rosendahl K, Spranger J, Horn D, Meynert A, Floyd JA, Prescott T, Anderson CA, ... ... Ponting CP, et al. Monoallelic and biallelic mutations in MAB21L2 cause a spectrum of major eye malformations. American Journal of Human Genetics. 94: 915-23. PMID 24906020 DOI: 10.1016/j.ajhg.2014.05.005  0.92
2014 Booth DG, Takagi M, Sanchez-Pulido L, Petfalski E, Vargiu G, Samejima K, Imamoto N, Ponting CP, Tollervey D, Earnshaw WC, Vagnarelli P. Ki-67 is a PP1-interacting protein that organises the mitotic chromosome periphery. Elife. 3: e01641. PMID 24867636 DOI: 10.7554/eLife.01641.001  0.92
2014 Lu M, Zak J, Chen S, Sanchez-Pulido L, Severson DT, Endicott J, Ponting CP, Schofield CJ, Lu X. A code for RanGDP binding in ankyrin repeats defines a nuclear import pathway. Cell. 157: 1130-45. PMID 24855949 DOI: 10.1016/j.cell.2014.05.006  0.92
2014 Marques AC, Ponting CP. Intergenic lncRNAs and the evolution of gene expression. Current Opinion in Genetics & Development. 27: 48-53. PMID 24852186 DOI: 10.1016/j.gde.2014.03.009  0.92
2014 Haerty W, Ponting CP. No gene in the genome makes sense except in the light of evolution. Annual Review of Genomics and Human Genetics. 15: 71-92. PMID 24773316 DOI: 10.1146/annurev-genom-090413-025621  0.92
2014 Wehrspaun CC, Ponting CP, Marques AC. Brain-expressed 3'UTR extensions strengthen miRNA cross-talk between ion channel/transporter encoding mRNAs. Frontiers in Genetics. 5: 41. PMID 24616735 DOI: 10.3389/fgene.2014.00041  0.92
2014 Vance KW, Sansom SN, Lee S, Chalei V, Kong L, Cooper SE, Oliver PL, Ponting CP. The long non-coding RNA Paupar regulates the expression of both local and distal genes. The Embo Journal. 33: 296-311. PMID 24488179 DOI: 10.1002/embj.201386225  0.92
2014 Sims D, Sudbery I, Ilott NE, Heger A, Ponting CP. Sequencing depth and coverage: key considerations in genomic analyses. Nature Reviews. Genetics. 15: 121-32. PMID 24434847 DOI: 10.1038/nrg3642  0.92
2014 Sims D, Ilott NE, Sansom SN, Sudbery IM, Johnson JS, Fawcett KA, Berlanga-Taylor AJ, Luna-Valero S, Ponting CP, Heger A. CGAT: computational genomics analysis toolkit. Bioinformatics (Oxford, England). 30: 1290-1. PMID 24395753 DOI: 10.1093/bioinformatics/btt756  0.92
2014 Rajan P, Sudbery IM, Villasevil ME, Mui E, Fleming J, Davis M, Ahmad I, Edwards J, Sansom OJ, Sims D, Ponting CP, Heger A, McMenemin RM, Pedley ID, Leung HY. Next-generation sequencing of advanced prostate cancer treated with androgen-deprivation therapy. European Urology. 66: 32-9. PMID 24054872 DOI: 10.1016/j.eururo.2013.08.011  0.92
2014 Davies G, Harris SE, Reynolds CA, Payton A, Knight HM, Liewald DC, Lopez LM, Luciano M, Gow AJ, Corley J, Henderson R, Murray C, Pattie A, Fox HC, Redmond P, ... ... Ponting CP, et al. A genome-wide association study implicates the APOE locus in nonpathological cognitive ageing. Molecular Psychiatry. 19: 76-87. PMID 23207651 DOI: 10.1038/mp.2012.159  0.92
2013 Marques AC, Hughes J, Graham B, Kowalczyk MS, Higgs DR, Ponting CP. Chromatin signatures at transcriptional start sites separate two equally populated yet distinct classes of intergenic long noncoding RNAs. Genome Biology. 14: R131. PMID 24289259 DOI: 10.1186/gb-2013-14-11-r131  0.92
2013 Belgard TG, Montiel JF, Wang WZ, García-Moreno F, Margulies EH, Ponting CP, Molnár Z. Adult pallium transcriptomes surprise in not reflecting predicted homologies across diverse chicken and mouse pallial sectors. Proceedings of the National Academy of Sciences of the United States of America. 110: 13150-5. PMID 23878249 DOI: 10.1073/pnas.1307444110  0.92
2013 Sanchez-Pulido L, Ponting CP. Tiki, at the head of a new superfamily of enzymes. Bioinformatics (Oxford, England). 29: 2371-4. PMID 23868957 DOI: 10.1093/bioinformatics/btt412  0.92
2013 Young RS, Ponting CP. Identification and function of long non-coding RNAs. Essays in Biochemistry. 54: 113-26. PMID 23829531 DOI: 10.1042/bse0540113  0.92
2013 Bassett AR, Tibbit C, Ponting CP, Liu JL. Highly efficient targeted mutagenesis of Drosophila with the CRISPR/Cas9 system. Cell Reports. 4: 220-8. PMID 23827738 DOI: 10.1016/j.celrep.2013.06.020  0.92
2013 Heger A, Webber C, Goodson M, Ponting CP, Lunter G. GAT: a simulation framework for testing the association of genomic intervals. Bioinformatics (Oxford, England). 29: 2046-8. PMID 23782611 DOI: 10.1093/bioinformatics/btt343  0.92
2013 Noh HJ, Ponting CP, Boulding HC, Meader S, Betancur C, Buxbaum JD, Pinto D, Marshall CR, Lionel AC, Scherer SW, Webber C. Network topologies and convergent aetiologies arising from deletions and duplications observed in individuals with autism. Plos Genetics. 9: e1003523. PMID 23754953 DOI: 10.1371/journal.pgen.1003523  0.92
2013 Babbs C, Roberts NA, Sanchez-Pulido L, McGowan SJ, Ahmed MR, Brown JM, Sabry MA, Bentley DR, McVean GA, Donnelly P, Gileadi O, Ponting CP, Higgs DR, Buckle VJ. Homozygous mutations in a predicted endonuclease are a novel cause of congenital dyserythropoietic anemia type I. Haematologica. 98: 1383-7. PMID 23716552 DOI: 10.3324/haematol.2013.089490  0.92
2013 Haerty W, Ponting CP. Mutations within lncRNAs are effectively selected against in fruitfly but not in human. Genome Biology. 14: R49. PMID 23710818 DOI: 10.1186/gb-2013-14-5-r49  0.92
2013 Doolittle WF, Fraser P, Gerstein MB, Graveley BR, Henikoff S, Huttenhower C, Oshlack A, Ponting CP, Rinn JL, Schatz MC, Ule J, Weigel D, Weinstock GM. Sixty years of genome biology. Genome Biology. 14: 113. PMID 23651518 DOI: 10.1186/gb-2013-14-4-113  0.92
2013 Amemiya CT, Alföldi J, Lee AP, Fan S, Philippe H, Maccallum I, Braasch I, Manousaki T, Schneider I, Rohner N, Organ C, Chalopin D, Smith JJ, Robinson M, Dorrington RA, ... ... Ponting CP, et al. The African coelacanth genome provides insights into tetrapod evolution. Nature. 496: 311-6. PMID 23598338 DOI: 10.1038/nature12027  0.92
2013 Li YI, Kong L, Ponting CP, Haerty W. Rapid evolution of Beta-keratin genes contribute to phenotypic differences that distinguish turtles and birds from other reptiles. Genome Biology and Evolution. 5: 923-33. PMID 23576313 DOI: 10.1093/gbe/evt060  0.92
2013 Ilott NE, Ponting CP. Predicting long non-coding RNAs using RNA sequencing. Methods (San Diego, Calif.). 63: 50-9. PMID 23541739 DOI: 10.1016/j.ymeth.2013.03.019  0.92
2013 Shaffer HB, Minx P, Warren DE, Shedlock AM, Thomson RC, Valenzuela N, Abramyan J, Amemiya CT, Badenhorst D, Biggar KK, Borchert GM, Botka CW, Bowden RM, Braun EL, Bronikowski AM, ... ... Ponting CP, et al. The western painted turtle genome, a model for the evolution of extreme physiological adaptations in a slowly evolving lineage. Genome Biology. 14: R28. PMID 23537068 DOI: 10.1186/gb-2013-14-3-r28  0.92
2013 Zhu M, Settele F, Kotak S, Sanchez-Pulido L, Ehret L, Ponting CP, Gönczy P, Hoffmann I. MISP is a novel Plk1 substrate required for proper spindle orientation and mitotic progression. The Journal of Cell Biology. 200: 773-87. PMID 23509069 DOI: 10.1083/jcb.201207050  0.92
2013 Long HK, Sims D, Heger A, Blackledge NP, Kutter C, Wright ML, Grützner F, Odom DT, Patient R, Ponting CP, Klose RJ. Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates. Elife. 2: e00348. PMID 23467541 DOI: 10.7554/eLife.00348  0.92
2013 Rands CM, Darling A, Fujita M, Kong L, Webster MT, Clabaut C, Emes RD, Heger A, Meader S, Hawkins MB, Eisen MB, Teiling C, Affourtit J, Boese B, Grant PR, ... ... Ponting CP, et al. Insights into the evolution of Darwin's finches from comparative analysis of the Geospiza magnirostris genome sequence. Bmc Genomics. 14: 95. PMID 23402223 DOI: 10.1186/1471-2164-14-95  0.92
2013 Rodgers W, Ancliff P, Ponting CP, Sanchez-Pulido L, Burns S, Hayman M, Kimonis V, Sebire N, Bulstrode N, Harper JI. Squamous cell carcinoma in a child with Clericuzio-type poikiloderma with neutropenia. The British Journal of Dermatology. 168: 665-7. PMID 22924337 DOI: 10.1111/bjd.12016  0.92
2012 Ponting CP. Loaded dice for human genome mutation. Cell. 151: 1399-400. PMID 23260131 DOI: 10.1016/j.cell.2012.12.002  0.92
2012 Farcas AM, Blackledge NP, Sudbery I, Long HK, McGouran JF, Rose NR, Lee S, Sims D, Cerase A, Sheahan TW, Koseki H, Brockdorff N, Ponting CP, Kessler BM, Klose RJ. KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands. Elife. 1: e00205. PMID 23256043 DOI: 10.7554/eLife.00205  0.92
2012 Marques AC, Tan J, Lee S, Kong L, Heger A, Ponting CP. Evidence for conserved post-transcriptional roles of unitary pseudogenes and for frequent bifunctionality of mRNAs. Genome Biology. 13: R102. PMID 23153069 DOI: 10.1186/gb-2012-13-11-r102  0.92
2012 Goodson M, Rust MB, Witke W, Bannerman D, Mott R, Ponting CP, Flint J. Cofilin-1: a modulator of anxiety in mice. Plos Genetics. 8: e1002970. PMID 23055942 DOI: 10.1371/journal.pgen.1002970  0.92
2012 Ponting CP, Oliver PL. Brain, know thy transcriptome, know thyself. Neuron. 75: 543-5. PMID 22920245 DOI: 10.1016/j.neuron.2012.08.005  0.92
2012 Muñoz IM, MacArtney T, Sanchez-Pulido L, Ponting CP, Rocha S, Rouse J. Family with sequence similarity 60A (FAM60A) protein is a cell cycle-fluctuating regulator of the SIN3-HDAC1 histone deacetylase complex. The Journal of Biological Chemistry. 287: 32346-53. PMID 22865885 DOI: 10.1074/jbc.M112.382499  0.92
2012 Kutter C, Watt S, Stefflova K, Wilson MD, Goncalves A, Ponting CP, Odom DT, Marques AC. Rapid turnover of long noncoding RNAs and the evolution of gene expression. Plos Genetics. 8: e1002841. PMID 22844254 DOI: 10.1371/journal.pgen.1002841  0.92
2012 Prüfer K, Munch K, Hellmann I, Akagi K, Miller JR, Walenz B, Koren S, Sutton G, Kodira C, Winer R, Knight JR, Mullikin JC, Meader SJ, Ponting CP, Lunter G, et al. The bonobo genome compared with the chimpanzee and human genomes. Nature. 486: 527-31. PMID 22722832 DOI: 10.1038/nature11128  0.92
2012 Nellåker C, Keane TM, Yalcin B, Wong K, Agam A, Belgard TG, Flint J, Adams DJ, Frankel WN, Ponting CP. The genomic landscape shaped by selection on transposable elements across 18 mouse strains. Genome Biology. 13: R45. PMID 22703977 DOI: 10.1186/gb-2012-13-6-r45  0.92
2012 Sanchez-Pulido L, Kong L, Ponting CP. A common ancestry for BAP1 and Uch37 regulators. Bioinformatics (Oxford, England). 28: 1953-6. PMID 22645167 DOI: 10.1093/bioinformatics/bts319  0.92
2012 Kowalczyk MS, Hughes JR, Babbs C, Sanchez-Pulido L, Szumska D, Sharpe JA, Sloane-Stanley JA, Morriss-Kay GM, Smoot LB, Roberts AE, Watkins H, Bhattacharya S, Gibbons RJ, Ponting CP, Wood WG, et al. Nprl3 is required for normal development of the cardiovascular system. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 23: 404-15. PMID 22538705 DOI: 10.1007/s00335-012-9398-y  0.92
2012 Danecek P, Nellåker C, McIntyre RE, Buendia-Buendia JE, Bumpstead S, Ponting CP, Flint J, Durbin R, Keane TM, Adams DJ. High levels of RNA-editing site conservation amongst 15 laboratory mouse strains. Genome Biology. 13: 26. PMID 22524474 DOI: 10.1186/gb-2012-13-4-r26  0.92
2012 Young RS, Marques AC, Tibbit C, Haerty W, Bassett AR, Liu JL, Ponting CP. Identification and properties of 1,119 candidate lincRNA loci in the Drosophila melanogaster genome. Genome Biology and Evolution. 4: 427-42. PMID 22403033 DOI: 10.1093/gbe/evs020  0.92
2012 Scally A, Dutheil JY, Hillier LW, Jordan GE, Goodhead I, Herrero J, Hobolth A, Lappalainen T, Mailund T, Marques-Bonet T, McCarthy S, Montgomery SH, Schwalie PC, Tang YA, Ward MC, ... ... Ponting CP, et al. Insights into hominid evolution from the gorilla genome sequence. Nature. 483: 169-75. PMID 22398555 DOI: 10.1038/nature10842  0.92
2012 Parkinson NJ, Maslau S, Ferneyhough B, Zhang G, Gregory L, Buck D, Ragoussis J, Ponting CP, Fischer MD. Preparation of high-quality next-generation sequencing libraries from picogram quantities of target DNA. Genome Research. 22: 125-33. PMID 22090378 DOI: 10.1101/gr.124016.111  0.92
2012 Axelsson E, Webster MT, Ratnakumar A, Ponting CP, Lindblad-Toh K. Death of PRDM9 coincides with stabilization of the recombination landscape in the dog genome. Genome Research. 22: 51-63. PMID 22006216 DOI: 10.1101/gr.124123.111  0.92
2012 Axelsson E, Webster MT, Ratnakumar A, Ponting CP, Lindblad-Toh K. Death of PRDM9 coincides with stabilization of the recombination landscape in the dog genome (Genome Research (2012) 22, (51-63)) Genome Research. 22: 810.  0.92
2011 Marques AC, Tan J, Ponting CP. Wrangling for microRNAs provokes much crosstalk. Genome Biology. 12: 132. PMID 22104690 DOI: 10.1186/gb-2011-12-11-132  0.92
2011 Keane TM, Goodstadt L, Danecek P, White MA, Wong K, Yalcin B, Heger A, Agam A, Slater G, Goodson M, Furlotte NA, Eskin E, NellÃ¥ker C, Whitley H, Cleak J, ... ... Ponting CP, et al. Mouse genomic variation and its effect on phenotypes and gene regulation. Nature. 477: 289-94. PMID 21921910 DOI: 10.1038/nature10413  0.92
2011 Alföldi J, Di Palma F, Grabherr M, Williams C, Kong L, Mauceli E, Russell P, Lowe CB, Glor RE, Jaffe JD, Ray DA, Boissinot S, Shedlock AM, Botka C, Castoe TA, ... ... Ponting CP, et al. The genome of the green anole lizard and a comparative analysis with birds and mammals. Nature. 477: 587-91. PMID 21881562 DOI: 10.1038/nature10390  0.92
2011 Ponting CP, Hardison RC. What fraction of the human genome is functional? Genome Research. 21: 1769-76. PMID 21875934 DOI: 10.1101/gr.116814.110  0.92
2011 Belgard TG, Marques AC, Oliver PL, Abaan HO, Sirey TM, Hoerder-Suabedissen A, García-Moreno F, Molnár Z, Margulies EH, Ponting CP. A transcriptomic atlas of mouse neocortical layers. Neuron. 71: 605-16. PMID 21867878 DOI: 10.1016/j.neuron.2011.06.039  0.92
2011 Wong ES, Papenfuss AT, Heger A, Hsu AL, Ponting CP, Miller RD, Fenelon JC, Renfree MB, Gibbs RA, Belov K. Transcriptomic analysis supports similar functional roles for the two thymuses of the tammar wallaby. Bmc Genomics. 12: 420. PMID 21854594 DOI: 10.1186/1471-2164-12-420  0.92
2011 Sanchez-Pulido L, Ponting CP. Structure and evolutionary history of DISC1. Human Molecular Genetics. 20: R175-81. PMID 21852244 DOI: 10.1093/hmg/ddr374  0.92
2011 Vagnarelli P, Ribeiro S, Sennels L, Sanchez-Pulido L, de Lima Alves F, Verheyen T, Kelly DA, Ponting CP, Rappsilber J, Earnshaw WC. Repo-Man coordinates chromosomal reorganization with nuclear envelope reassembly during mitotic exit. Developmental Cell. 21: 328-42. PMID 21820363 DOI: 10.1016/j.devcel.2011.06.020  0.92
2011 Fujita MK, Edwards SV, Ponting CP. The Anolis lizard genome: an amniote genome without isochores. Genome Biology and Evolution. 3: 974-84. PMID 21795750 DOI: 10.1093/gbe/evr072  0.92
2011 Clark MB, Amaral PP, Schlesinger FJ, Dinger ME, Taft RJ, Rinn JL, Ponting CP, Stadler PF, Morris KV, Morillon A, Rozowsky JS, Gerstein MB, Wahlestedt C, Hayashizaki Y, Carninci P, et al. The reality of pervasive transcription. Plos Biology. 9: e1000625; discussion. PMID 21765801 DOI: 10.1371/journal.pbio.1000625  0.92
2011 Ponting CP, Nellåker C, Meader S. Rapid turnover of functional sequence in human and other genomes. Annual Review of Genomics and Human Genetics. 12: 275-99. PMID 21721940 DOI: 10.1146/annurev-genom-090810-183115  0.92
2011 Boos D, Sanchez-Pulido L, Rappas M, Pearl LH, Oliver AW, Ponting CP, Diffley JF. Regulation of DNA replication through Sld3-Dpb11 interaction is conserved from yeast to humans. Current Biology : Cb. 21: 1152-7. PMID 21700459 DOI: 10.1016/j.cub.2011.05.057  0.92
2011 Sanchez-Pulido L, Ponting CP. Cdc45: the missing RecJ ortholog in eukaryotes? Bioinformatics (Oxford, England). 27: 1885-8. PMID 21653514 DOI: 10.1093/bioinformatics/btr332  0.92
2011 Mills RE, Pittard WS, Mullaney JM, Farooq U, Creasy TH, Mahurkar AA, Kemeza DM, Strassler DS, Ponting CP, Webber C, Devine SE. Natural genetic variation caused by small insertions and deletions in the human genome. Genome Research. 21: 830-9. PMID 21460062 DOI: 10.1101/gr.115907.110  0.92
2011 Ponting CP. What are the genomic drivers of the rapid evolution of PRDM9? Trends in Genetics : Tig. 27: 165-71. PMID 21388701 DOI: 10.1016/j.tig.2011.02.001  0.92
2011 Blair HJ, Tompson S, Liu YN, Campbell J, MacArthur K, Ponting CP, Ruiz-Perez VL, Goodship JA. Evc2 is a positive modulator of Hedgehog signalling that interacts with Evc at the cilia membrane and is also found in the nucleus. Bmc Biology. 9: 14. PMID 21356043 DOI: 10.1186/1741-7007-9-14  0.92
2011 Locke DP, Hillier LW, Warren WC, Worley KC, Nazareth LV, Muzny DM, Yang SP, Wang Z, Chinwalla AT, Minx P, Mitreva M, Cook L, Delehaunty KD, Fronick C, Schmidt H, ... ... Ponting CP, et al. Comparative and demographic analysis of orang-utan genomes. Nature. 469: 529-33. PMID 21270892 DOI: 10.1038/nature09687  0.92
2011 Coward K, Ponting CP, Zhang N, Young C, Huang CJ, Chou CM, Kashir J, Fissore RA, Parrington J. Identification and functional analysis of an ovarian form of the egg activation factor phospholipase C zeta (PLCζ) in pufferfish. Molecular Reproduction and Development. 78: 48-56. PMID 21268182 DOI: 10.1002/mrd.21262  0.92
2011 Shaikh TH, Haldeman-Englert C, Geiger EA, Ponting CP, Webber C. Genes and biological processes commonly disrupted in rare and heterogeneous developmental delay syndromes. Human Molecular Genetics. 20: 880-93. PMID 21147756 DOI: 10.1093/hmg/ddq527  0.92
2011 Goodstadt L, Ponting CP. Is the control of recombination conserved among diverse eukaryotes? Heredity. 106: 710-1. PMID 20606688 DOI: 10.1038/hdy.2010.88  0.92
2010 Duro E, Lundin C, Ask K, Sanchez-Pulido L, MacArtney TJ, Toth R, Ponting CP, Groth A, Helleday T, Rouse J. Identification of the MMS22L-TONSL complex that promotes homologous recombination. Molecular Cell. 40: 632-44. PMID 21055984 DOI: 10.1016/j.molcel.2010.10.023  0.92
2010 Ohta S, Bukowski-Wills JC, Sanchez-Pulido L, Alves Fde L, Wood L, Chen ZA, Platani M, Fischer L, Hudson DF, Ponting CP, Fukagawa T, Earnshaw WC, Rappsilber J. The protein composition of mitotic chromosomes determined using multiclassifier combinatorial proteomics. Cell. 142: 810-21. PMID 20813266 DOI: 10.1016/j.cell.2010.07.047  0.92
2010 Ponting CP, Belgard TG. Transcribed dark matter: meaning or myth? Human Molecular Genetics. 19: R162-8. PMID 20798109 DOI: 10.1093/hmg/ddq362  0.92
2010 Ramagopalan SV, Heger A, Berlanga AJ, Maugeri NJ, Lincoln MR, Burrell A, Handunnetthi L, Handel AE, Disanto G, Orton SM, Watson CT, Morahan JM, Giovannoni G, Ponting CP, Ebers GC, et al. A ChIP-seq defined genome-wide map of vitamin D receptor binding: associations with disease and evolution. Genome Research. 20: 1352-60. PMID 20736230 DOI: 10.1101/gr.107920.110  0.92
2010 Meader S, Ponting CP, Lunter G. Massive turnover of functional sequence in human and other mammalian genomes. Genome Research. 20: 1335-43. PMID 20693480 DOI: 10.1101/gr.108795.110  0.92
2010 Chodroff RA, Goodstadt L, Sirey TM, Oliver PL, Davies KE, Green ED, Molnár Z, Ponting CP. Long noncoding RNA genes: conservation of sequence and brain expression among diverse amniotes. Genome Biology. 11: R72. PMID 20624288 DOI: 10.1186/gb-2010-11-7-r72  0.92
2010 Sanchez-Pulido L, Diffley JF, Ponting CP. Homology explains the functional similarities of Treslin/Ticrr and Sld3. Current Biology : Cb. 20: R509-10. PMID 20620901 DOI: 10.1016/j.cub.2010.05.021  0.92
2010 Nam K, Mugal C, Nabholz B, Schielzeth H, Wolf JB, Backström N, Künstner A, Balakrishnan CN, Heger A, Ponting CP, Clayton DF, Ellegren H. Molecular evolution of genes in avian genomes. Genome Biology. 11: R68. PMID 20573239 DOI: 10.1186/gb-2010-11-6-r68  0.92
2010 Hehir-Kwa JY, Wieskamp N, Webber C, Pfundt R, Brunner HG, Gilissen C, de Vries BB, Ponting CP, Veltman JA. Accurate distinction of pathogenic from benign CNVs in mental retardation. Plos Computational Biology. 6: e1000752. PMID 20421931 DOI: 10.1371/journal.pcbi.1000752  0.92
2010 Warren WC, Clayton DF, Ellegren H, Arnold AP, Hillier LW, Künstner A, Searle S, White S, Vilella AJ, Fairley S, Heger A, Kong L, Ponting CP, Jarvis ED, Mello CV, et al. The genome of a songbird. Nature. 464: 757-62. PMID 20360741 DOI: 10.1038/nature08819  0.92
2010 Murton BL, Chin WL, Ponting CP, Itzhaki LS. Characterising the binding specificities of the subunits associated with the KMT2/Set1 histone lysine methyltransferase. Journal of Molecular Biology. 398: 481-8. PMID 20347846 DOI: 10.1016/j.jmb.2010.03.036  0.92
2010 Meader S, Hillier LW, Locke D, Ponting CP, Lunter G. Genome assembly quality: assessment and improvement using the neutral indel model. Genome Research. 20: 675-84. PMID 20305016 DOI: 10.1101/gr.096966.109  0.92
2010 Kong L, Lovell PV, Heger A, Mello CV, Ponting CP. Accelerated evolution of PAK3- and PIM1-like kinase gene families in the zebra finch, Taeniopygia guttata. Molecular Biology and Evolution. 27: 1923-34. PMID 20237222 DOI: 10.1093/molbev/msq080  0.92
2010 Bayne EH, White SA, Kagansky A, Bijos DA, Sanchez-Pulido L, Hoe KL, Kim DU, Park HO, Ponting CP, Rappsilber J, Allshire RC. Stc1: a critical link between RNAi and chromatin modification required for heterochromatin integrity. Cell. 140: 666-77. PMID 20211136 DOI: 10.1016/j.cell.2010.01.038  0.92
2010 Ponting CP, Meader SJ, Lunter G. Most of the 6.5% - 10% of human DNA bases that are functional now will soon be turned over Genome Biology. 11. DOI: 10.1186/gb-2010-11-s1-i10  0.92
2009 Oliver PL, Goodstadt L, Bayes JJ, Birtle Z, Roach KC, Phadnis N, Beatson SA, Lunter G, Malik HS, Ponting CP. Accelerated evolution of the Prdm9 speciation gene across diverse metazoan taxa. Plos Genetics. 5: e1000753. PMID 19997497 DOI: 10.1371/journal.pgen.1000753  0.92
2009 Marques AC, Ponting CP. Catalogues of mammalian long noncoding RNAs: Modest conservation and incompleteness Genome Biology. 10. PMID 19895688 DOI: 10.1186/gb-2009-10-11-r124  0.92
2009 Hautbergue GM, Hung ML, Walsh MJ, Snijders AP, Chang CT, Jones R, Ponting CP, Dickman MJ, Wilson SA. UIF, a New mRNA export adaptor that works together with REF/ALY, requires FACT for recruitment to mRNA. Current Biology : Cb. 19: 1918-24. PMID 19836239 DOI: 10.1016/j.cub.2009.09.041  0.92
2009 Ponjavic J, Oliver PL, Lunter G, Ponting CP. Genomic and transcriptional co-localization of protein-coding and long non-coding RNA pairs in the developing brain. Plos Genetics. 5: e1000617. PMID 19696892 DOI: 10.1371/journal.pgen.1000617  0.92
2009 Ponting CP, Goodstadt L. Separating derived from ancestral features of mouse and human genomes Biochemical Society Transactions. 37: 734-739. PMID 19614585 DOI: 10.1042/BST0370734  0.92
2009 Muñoz IM, Hain K, Déclais AC, Gardiner M, Toh GW, Sanchez-Pulido L, Heuckmann JM, Toth R, Macartney T, Eppink B, Kanaar R, Ponting CP, Lilley DM, Rouse J. Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair. Molecular Cell. 35: 116-27. PMID 19595721 DOI: 10.1016/j.molcel.2009.06.020  0.92
2009 Sanchez-Pulido L, Pidoux AL, Ponting CP, Allshire RC. Common ancestry of the CENP-A chaperones Scm3 and HJURP. Cell. 137: 1173-4. PMID 19563746 DOI: 10.1016/j.cell.2009.06.010  0.92
2009 Webber C, Hehir-Kwa JY, Nguyen DQ, de Vries BB, Veltman JA, Ponting CP. Forging links between human mental retardation-associated CNVs and mouse gene knockout models. Plos Genetics. 5: e1000531. PMID 19557186 DOI: 10.1371/journal.pgen.1000531  0.92
2009 Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X, Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y, Meric P, Maglott D, Birtle Z, ... ... Ponting CP, et al. Lineage-specific biology revealed by a finished genome assembly of the mouse. Plos Biology. 7: e1000112. PMID 19468303 DOI: 10.1371/journal.pbio.1000112  0.92
2009 Heger A, Ponting CP, Holmes I. Accurate estimation of gene evolutionary rates using XRATE, with an application to transmembrane proteins. Molecular Biology and Evolution. 26: 1715-21. PMID 19380462 DOI: 10.1093/molbev/msp080  0.92
2009 Ponting CP, Oliver PL, Reik W. Evolution and functions of long noncoding RNAs. Cell. 136: 629-41. PMID 19239885 DOI: 10.1016/j.cell.2009.02.006  0.92
2008 Abd El-Aziz MM, Barragan I, O'Driscoll CA, Goodstadt L, Prigmore E, Borrego S, Mena M, Pieras JI, El-Ashry MF, Safieh LA, Shah A, Cheetham ME, Carter NP, Chakarova C, Ponting CP, et al. EYS, encoding an ortholog of Drosophila spacemaker, is mutated in autosomal recessive retinitis pigmentosa. Nature Genetics. 40: 1285-7. PMID 18836446 DOI: 10.1038/ng.241  0.92
2008 Nguyen DQ, Webber C, Hehir-Kwa J, Pfundt R, Veltman J, Ponting CP. Reduced purifying selection prevails over positive selection in human copy number variant evolution. Genome Research. 18: 1711-23. PMID 18687881 DOI: 10.1101/gr.077289.108  0.92
2008 Ponting CP. The functional repertoires of metazoan genomes Nature Reviews Genetics. 9: 689-698. PMID 18663365 DOI: 10.1038/nrg2413  0.92
2008 Warren WC, Hillier LW, Marshall Graves JA, Birney E, Ponting CP, Grützner F, Belov K, Miller W, Clarke L, Chinwalla AT, Yang SP, Heger A, Locke DP, Miethke P, Waters PD, et al. Genome analysis of the platypus reveals unique signatures of evolution. Nature. 453: 175-83. PMID 18464734 DOI: 10.1038/nature06936  0.92
2008 Whittington CM, Papenfuss AT, Bansal P, Torres AM, Wong ES, Deakin JE, Graves T, Alsop A, Schatzkamer K, Kremitzki C, Ponting CP, Temple-Smith P, Warren WC, Kuchel PW, Belov K. Defensins and the convergent evolution of platypus and reptile venom genes. Genome Research. 18: 986-94. PMID 18463304 DOI: 10.1101/gr.7149808  0.92
2008 Laukaitis CM, Heger A, Blakley TD, Munclinger P, Ponting CP, Karn RC. Rapid bursts of androgen-binding protein (Abp) gene duplication occurred independently in diverse mammals Bmc Evolutionary Biology. 8. PMID 18269759 DOI: 10.1186/1471-2148-8-46  0.92
2008 Bakrania P, Efthymiou M, Klein JC, Salt A, Bunyan DJ, Wyatt A, Ponting CP, Martin A, Williams S, Lindley V, Gilmore J, Restori M, Robson AG, Neveu MM, Holder GE, et al. Mutations in BMP4 cause eye, brain, and digit developmental anomalies: overlap between the BMP4 and hedgehog signaling pathways. American Journal of Human Genetics. 82: 304-19. PMID 18252212 DOI: 10.1016/j.ajhg.2007.09.023  0.92
2008 Ramm SA, Oliver PL, Ponting CP, Stockley P, Emes RD. Sexual selection and the adaptive evolution of mammalian ejaculate proteins. Molecular Biology and Evolution. 25: 207-19. PMID 18032407 DOI: 10.1093/molbev/msm242  0.92
2008 Heger A, Ponting CP. OPTIC: Orthologous and paralogous transcripts in clades Nucleic Acids Research. 36: D267-D270. PMID 17933761 DOI: 10.1093/nar/gkm852  0.92
2008 Warren WC, Hillier LW, Marshall Graves JA, Birney E, Ponting CP, Grützner F, Belov K, Miller W, Clarke L, Chinwalla AT, Yang SP, Heger A, Locke DP, Miethke P, Waters PD, et al. Genome analysis of the platypus reveals unique signatures of evolution (Nature (2008) 453, (175-183)) Nature. 455: 256. DOI: 10.1038/nature07253  0.92
2007 Heger A, Ponting CP. Variable strength of translational selection among 12 Drosophila species Genetics. 177: 1337-1348. PMID 18039870 DOI: 10.1534/genetics.107.070466  0.92
2007 Gerken T, Girard CA, Tung YC, Webby CJ, Saudek V, Hewitson KS, Yeo GS, McDonough MA, Cunliffe S, McNeill LA, Galvanovskis J, Rorsman P, Robins P, Prieur X, Coll AP, ... ... Ponting CP, et al. The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. Science (New York, N.Y.). 318: 1469-72. PMID 17991826 DOI: 10.1126/science.1151710  0.92
2007 Heger A, Ponting CP. Evolutionary rate analyses of orthologs and paralogs from 12 Drosophila genomes Genome Research. 17: 1837-1849. PMID 17989258 DOI: 10.1101/gr.6249707  0.92
2007 Ponjavic J, Ponting CP. The long and the short of RNA maps Bioessays. 29: 1077-1080. PMID 17935150 DOI: 10.1002/bies.20669  0.92
2007 Chakarova CF, Papaioannou MG, Khanna H, Lopez I, Waseem N, Shah A, Theis T, Friedman J, Maubaret C, Bujakowska K, Veraitch B, Abd El-Aziz MM, Prescott de Q, Parapuram SK, Bickmore WA, ... ... Ponting CP, et al. Mutations in TOPORS cause autosomal dominant retinitis pigmentosa with perivascular retinal pigment epithelium atrophy. American Journal of Human Genetics. 81: 1098-103. PMID 17924349 DOI: 10.1086/521953  0.92
2007 Goodstadt L, Heger A, Webber C, Ponting CP. An analysis of the gene complement of a marsupial, Monodelphis domestica: evolution of lineage-specific genes and giant chromosomes. Genome Research. 17: 969-81. PMID 17495010 DOI: 10.1101/gr.6093907  0.92
2007 Ponjavic J, Ponting CP, Lunter G. Functionality or transcriptional noise? Evidence for selection within long noncoding RNAs Genome Research. 17: 556-565. PMID 17387145 DOI: 10.1101/gr.6036807  0.92
2006 Birtle Z, Ponting CP. Meisetz and the birth of the KRAB motif Bioinformatics. 22: 2841-2845. PMID 17032681 DOI: 10.1093/bioinformatics/btl498  0.92
2006 Goodstadt L, Ponting CP. Phylogenetic reconstruction of orthology, paralogy, and conserved synteny for dog and human Plos Computational Biology. 2: 1134-1150. PMID 17009864 DOI: 10.1371/journal.pcbi.0020133  0.92
2006 Ponting CP, Lunter G. Signatures of adaptive evolution within human non-coding sequence Human Molecular Genetics. 15: R170-R175. PMID 16987880 DOI: 10.1093/hmg/ddl182  0.92
2006 Ponting CP, Lunter G. Evolutionary biology: Human brain gene wins genome race Nature. 443: 149-150. PMID 16915234 DOI: 10.1038/nature05154  0.92
2006 Crow YJ, Leitch A, Hayward BE, Garner A, Parmar R, Griffith E, Ali M, Semple C, Aicardi J, Babul-Hirji R, Baumann C, Baxter P, Bertini E, Chandler KE, Chitayat D, ... ... Ponting CP, et al. Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infection Nature Genetics. 38: 910-916. PMID 16845400 DOI: 10.1038/ng1842  0.92
2006 Cordes FS, Kraiczy P, Roversi P, Simon MM, Brade V, Jahraus O, Wallis R, Goodstadt L, Ponting CP, Skerka C, Zipfel PF, Wallich R, Lea SM. Structure-function mapping of BbCRASP-1, the key complement factor H and FHL-1 binding protein of Borrelia burgdorferi International Journal of Medical Microbiology. 296: 177-184. PMID 16530476 DOI: 10.1016/j.ijmm.2006.01.011  0.92
2006 Bunney TD, Harris R, Gandarillas NL, Josephs MB, Roe SM, Sorli SC, Paterson HF, Rodrigues-Lima F, Esposito D, Ponting CP, Gierschik P, Pearl LH, Driscoll PC, Katan M. Structural and mechanistic insights into ras association domains of phospholipase C epsilon. Molecular Cell. 21: 495-507. PMID 16483931 DOI: 10.1016/j.molcel.2006.01.008  0.92
2006 Nguyen DQ, Webber C, Ponting CP. Bias of selection on human copy-number variants. Plos Genetics. 2: e20. PMID 16482228 DOI: 10.1371/journal.pgen.0020020  0.92
2006 Ponting CP. A novel domain suggests a ciliary function for ASPM, a brain size determining gene Bioinformatics. 22: 1031-1035. PMID 16443634 DOI: 10.1093/bioinformatics/btl022  0.92
2006 Lunter G, Ponting CP, Hein J. Genome-wide identification of human functional DNA using a neutral indel model Plos Computational Biology. 2. DOI: 10.1371/journal.pcbi.0020005  0.92
2006 Nguyen DQ, Webber C, Ponting CP. Bias of selection on human copy-number variants Plos Genetics. 2: 198-207. DOI: 10.1016/j.mssp.2006.01.060  0.92
2005 Lindblad-Toh K, Wade CM, Mikkelsen TS, Karlsson EK, Jaffe DB, Kamal M, Clamp M, Chang JL, Kulbokas EJ, Zody MC, Mauceli E, Xie X, Breen M, Wayne RK, Ostrander EA, ... Ponting CP, et al. Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature. 438: 803-19. PMID 16341006 DOI: 10.1038/nature04338  0.92
2005 Webber C, Ponting CP. Hotspots of mutation and breakage in dog and human chromosomes. Genome Research. 15: 1787-97. PMID 16339377 DOI: 10.1101/gr.3896805  0.92
2005 Winter EE, Ponting CP. Mammalian BEX, WEX and GASP genes: Coding and non-coding chimaerism sustained by gene conversion events Bmc Evolutionary Biology. 5. PMID 16221301 DOI: 10.1186/1471-2148-5-54  0.92
2005 Coward K, Ponting CP, Chang HY, Hibbitt O, Savolainen P, Jones KT, Parrington J. Phospholipase Czeta, the trigger of egg activation in mammals, is present in a non-mammalian species. Reproduction (Cambridge, England). 130: 157-63. PMID 16049153 DOI: 10.1530/rep.1.00707  0.92
2005 Laukaitis CM, Dlouhy SR, Emes RD, Ponting CP, Karn RC. Diverse spatial, temporal, and sexual expression of recently duplicated androgen-binding protein genes in Mus musculus. Bmc Evolutionary Biology. 5: 40. PMID 16018816 DOI: 10.1186/1471-2148-5-40  0.92
2005 Ponting CP, Goodstadt L. Usual suspects in complex disease European Journal of Human Genetics. 13: 269-270. PMID 15657602 DOI: 10.1038/sj.ejhg.5201354  0.92
2005 Mulder NJ, Apweiler R, Attwood TK, Bairoch A, Bateman A, Binns D, Bradley P, Bork P, Bucher P, Cerutti L, Copley R, Courcelle E, Das U, Durbin R, Fleischmann W, ... ... Ponting CP, et al. InterPro, progress and status in 2005. Nucleic Acids Research. 33: D201-5. PMID 15608177 DOI: 10.1093/nar/gki106  0.92
2004 . Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution. Nature. 432: 695-716. PMID 15592404 DOI: 10.1038/nature03154  0.92
2004 Beatson S, Ponting CP. GIFT domains: Linking eukaryotic intraflagellar transport and glycosylation to bacterial gliding Trends in Biochemical Sciences. 29: 396-399. PMID 15288869 DOI: 10.1016/j.tibs.2004.06.002  0.92
2004 Goodstadt L, Ponting CP. Vitamin K epoxide reductase: Homology, active site and catalytic mechanism Trends in Biochemical Sciences. 29: 289-292. PMID 15276181 DOI: 10.1016/j.tibs.2004.04.004  0.92
2004 Emes RD, Riley MC, Laukaitis CM, Goodstadt L, Karn RC, Ponting CP. Comparative evolutionary genomics of androgen-binding protein genes. Genome Research. 14: 1516-29. PMID 15256509 DOI: 10.1101/gr.2540304  0.92
2004 Huang H, Winter EE, Wang H, Weinstock KG, Xing H, Goodstadt L, Stenson PD, Cooper DN, Smith D, Albà MM, Ponting CP, Fechtel K. Evolutionary conservation and selection of human disease gene orthologs in the rat and mouse genomes Genome Biology. 5: R47. PMID 15239832  0.92
2004 Webber C, Ponting CP. Genes and homology. Current Biology : Cb. 14: R332-3. PMID 15120081 DOI: 10.1016/j.cub.2004.04.016  0.92
2004 Emes RD, Beatson SA, Ponting CP, Goodstadt L. Evolution and comparative genomics of odorant- and pheromone-associated genes in rodents. Genome Research. 14: 591-602. PMID 15060000 DOI: 10.1101/gr.1940604  0.92
2004 Taylor MS, Ponting CP, Copley RR. Occurrence and consequences of coding sequence insertions and deletions in Mammalian genomes. Genome Research. 14: 555-66. PMID 15059996 DOI: 10.1101/gr.1977804  0.92
2004 Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, ... ... Ponting CP, et al. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Nature. 428: 493-521. PMID 15057822 DOI: 10.1038/nature02426  1
2004 Zimdahl H, Nyakatura G, Brandt P, Schulz H, Hummel O, Fartmann B, Brett D, Droege M, Monti J, Lee YA, Sun Y, Zhao S, Winter EE, Ponting CP, Chen Y, et al. A SNP map of the rat genome generated from cDNA sequences. Science (New York, N.Y.). 303: 807. PMID 14764869 DOI: 10.1126/science.1092427  0.92
2004 Winter EE, Goodstadt L, Ponting CP. Elevated rates of protein secretion, evolution, and disease among tissue-specific genes Genome Research. 14: 54-61. PMID 14707169 DOI: 10.1101/gr.1924004  0.92
2004 Letunic I, Copley RR, Schmidt S, Ciccarelli FD, Doerks T, Schultz J, Ponting CP, Bork P. SMART 4.0: towards genomic data integration. Nucleic Acids Research. 32: D142-4. PMID 14681379 DOI: 10.1093/nar/gkh088  0.92
2003 Hughes-Davies L, Huntsman D, Ruas M, Fuks F, Bye J, Chin SF, Milner J, Brown LA, Hsu F, Gilks B, Nielsen T, Schulzer M, Chia S, Ragaz J, Cahn A, ... ... Ponting CP, et al. EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer. Cell. 115: 523-35. PMID 14651845 DOI: 10.1016/S0092-8674(03)00930-9  0.92
2003 Allen M, Heinzmann A, Noguchi E, Abecasis G, Broxholme J, Ponting CP, Bhattacharyya S, Tinsley J, Zhang Y, Holt R, Yvonne Jones E, Lench N, Carey A, Jones H, Dickens NJ, et al. Positional cloning of a novel gene influencing asthma from Chromosome 2q14 Nature Genetics. 35: 258-263. PMID 14566338 DOI: 10.1038/ng1256  0.92
2003 Vargas JD, Herpers B, McKie AT, Gledhill S, McDonnell J, van den Heuvel M, Davies KE, Ponting CP. Stromal cell-derived receptor 2 and cytochrome b561 are functional ferric reductases. Biochimica Et Biophysica Acta. 1651: 116-23. PMID 14499595 DOI: 10.1016/S1570-9639(03)00242-5  0.92
2003 Dickens NJ, Ponting CP. THoR: a tool for domain discovery and curation of multiple alignments Genome Biology. 4: R52. PMID 12914660  0.92
2003 Zhang Y, Leaves NI, Anderson GG, Ponting CP, Broxholme J, Holt R, Edser P, Bhattacharyya S, Dunham A, Adcock IM, Pulleyn L, Barnes PJ, Harper JI, Abecasis G, Cardon L, et al. Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma Nature Genetics. 34: 181-186. PMID 12754510 DOI: 10.1038/ng1166  0.92
2003 Hartmann-Petersen R, Semple CAM, Ponting CP, Hendil KB, Gordon C. UBA domain containing proteins in fission yeast International Journal of Biochemistry and Cell Biology. 35: 629-636. PMID 12672455 DOI: 10.1016/S1357-2725(02)00393-X  0.92
2003 Emes RD, Goodstadt L, Winter EE, Ponting CP. Comparison of the genomes of human and mouse lays the foundation of genome zoology. Human Molecular Genetics. 12: 701-9. PMID 12651866 DOI: 10.1093/hmg/ddg078  0.92
2003 Maurer-Stroh S, Dickens NJ, Hughes-Davies L, Kouzarides T, Eisenhaber F, Ponting CP. The Tudor domain 'Royal Family': Tudor, plant Agenet, Chromo, PWWP and MBT domains. Trends in Biochemical Sciences. 28: 69-74. PMID 12575993 DOI: 10.1016/S0968-0004(03)00004-5  0.92
2003 Guigo R, Dermitzakis ET, Agarwal P, Ponting CP, Parra G, Reymond A, Abril JF, Keibler E, Lyle R, Ucla C, Antonarakis SE, Brent MR. Comparison of mouse and human genomes followed by experimental verification yields an estimated 1,019 additional genes. Proceedings of the National Academy of Sciences of the United States of America. 100: 1140-5. PMID 12552088 DOI: 10.1073/pnas.0337561100  0.92
2003 Mulder NJ, Apweiler R, Attwood TK, Bairoch A, Barrell D, Bateman A, Binns D, Biswas M, Bradley P, Bork P, Bucher P, Copley RR, Courcelle E, Das U, Durbin R, ... ... Ponting CP, et al. The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Research. 31: 315-8. PMID 12520011 DOI: 10.1093/nar/gkg046  0.92
2002 Waterston RH, Lindblad-Toh K, Birney E, Rogers J, Abril JF, Agarwal P, Agarwala R, Ainscough R, Alexandersson M, An P, Antonarakis SE, Attwood J, Baertsch R, Bailey J, ... ... Ponting CP, et al. Initial sequencing and comparative analysis of the mouse genome. Nature. 420: 520-62. PMID 12466850 DOI: 10.1038/nature01262  1
2002 Copley RR, Ponting CP, Schultz J, Bork P. Sequence analysis of multidomain proteins: past perspectives and future directions. Advances in Protein Chemistry. 61: 75-98. PMID 12461821 DOI: 10.1016/S0065-3233(02)61002-2  0.92
2002 Mulder NJ, Apweiler R, Attwood TK, Bairoch A, Bateman A, Binns D, Biswas M, Bradley P, Bork P, Bucher P, Copley R, Courcelle E, Durbin R, Falquet L, Fleischmann W, ... ... Ponting CP, et al. InterPro: an integrated documentation resource for protein families, domains and functional sites. Briefings in Bioinformatics. 3: 225-35. PMID 12230031  0.92
2002 Vargas JD, Culetto E, Ponting CP, Miguel-Aliaga I, Davies KE, Sattelle DB. Cloning and developmental expression analysis of ltd-1, the Caenorhabditis elegans homologue of the mouse kyphoscoliosis (ky) gene. Mechanisms of Development. 117: 289-92. PMID 12204272 DOI: 10.1016/S0925-4773(02)00182-X  0.92
2002 Ponting CP. Novel domains and orthologues of eukaryotic transcription elongation factors Nucleic Acids Research. 30: 3643-3652. PMID 12202748  0.92
2002 Mott R, Schultz J, Bork P, Ponting CP. Predicting protein cellular localization using a domain projection method. Genome Research. 12: 1168-74. PMID 12176924 DOI: 10.1101/gr.96802  0.92
2002 Winter E, Ponting CP. TRAM, LAG1 and CLN8: Members of a novel family of lipid-sensing domains? Trends in Biochemical Sciences. 27: 381-383. PMID 12151215 DOI: 10.1016/S0968-0004(02)02154-0  0.92
2002 Ponting CP, Russell RR. The natural history of protein domains Annual Review of Biophysics and Biomolecular Structure. 31: 45-71. PMID 11988462 DOI: 10.1146/annurev.biophys.31.082901.134314  0.92
2002 Ponting CP, Hutton M, Nyborg A, Baker M, Jansen K, Golde TE. Identification of a novel family of presenilin homologues. Human Molecular Genetics. 11: 1037-44. PMID 11978763  0.92
2002 Dickens NJ, Beatson S, Ponting CP. Cadherin-like domains in α-dystroglycan, α/ε-sarcoglycan and yeast and bacterial proteins Current Biology. 12: R197-R199. PMID 11909544 DOI: 10.1016/S0960-9822(02)00748-0  0.92
2002 Ponting CP, Ito T, Moscat J, Diaz-Meco MT, Inagaki F, Sumimoto H. OPR, PC and AID: All in the PB1 family Trends in Biochemical Sciences. 27: 10. PMID 11796218 DOI: 10.1016/S0968-0004(01)02006-0  0.92
2002 Doerks T, Copley RR, Schultz J, Ponting CP, Bork P. Systematic identification of novel protein domain families associated with nuclear functions. Genome Research. 12: 47-56. PMID 11779830 DOI: 10.1101/  0.92
2002 Letunic I, Goodstadt L, Dickens NJ, Doerks T, Schultz J, Mott R, Ciccarelli F, Copley RR, Ponting CP, Bork P. Recent improvements to the SMART domain-based sequence annotation resource. Nucleic Acids Research. 30: 242-4. PMID 11752305  0.92
2001 Emes RD, Ponting CP. A new sequence motif linking lissencephaly, Treacher Collins and oral-facial-digital type 1 syndromes, microtubule dynamics and cell migration. Human Molecular Genetics. 10: 2813-20. PMID 11734546  0.92
2001 Ponting CP, Mott R, Bork P, Copley RR. Novel protein domains and repeats in Drosophila melanogaster: insights into structure, function, and evolution. Genome Research. 11: 1996-2008. PMID 11731489 DOI: 10.1101/gr.198701  0.92
2001 Brockington M, Blake DJ, Prandini P, Brown SC, Torelli S, Benson MA, Ponting CP, Estournet B, Romero NB, Mercuri E, Voit T, Sewry CA, Guicheney P, Muntoni F. Mutations in the fukutin-related protein gene (FKRP) cause a form of congenital muscular dystrophy with secondary laminin deficiency and abnormal glycosylation of α-dystroglycan American Journal of Human Genetics. 69: 1198-1209. PMID 11592034 DOI: 10.1086/324412  0.92
2001 Goodstadt L, Ponting CP. CHROMA: Consensus-based colouring of multiple alignments for publication Bioinformatics. 17: 845-846. PMID 11590103  0.92
2001 Lupas AN, Ponting CP, Russell RB. On the evolution of protein folds: are similar motifs in different protein folds the result of convergence, insertion, or relics of an ancient peptide world? Journal of Structural Biology. 134: 191-203. PMID 11551179 DOI: 10.1006/jsbi.2001.4393  0.92
2001 Andrade MA, Perez-Iratxeta C, Ponting CP. Protein repeats: structures, functions, and evolution. Journal of Structural Biology. 134: 117-31. PMID 11551174 DOI: 10.1006/jsbi.2001.4392  0.92
2000 Schultz J, Doerks T, Ponting CP, Copley RR, Bork P. More than 1,000 putative new human signalling proteins revealed by EST data mining. Nature Genetics. 25: 201-4. PMID 10835637 DOI: 10.1038/76069  0.92
2000 Ponting CP, Schultz J, Copley RR, Andrade MA, Bork P. Evolution of domain families. Advances in Protein Chemistry. 54: 185-244. PMID 10829229  0.92
2000 Andrade MA, Ponting CP, Gibson TJ, Bork P. Homology-based method for identification of protein repeats using statistical significance estimates. Journal of Molecular Biology. 298: 521-37. PMID 10772867 DOI: 10.1006/jmbi.2000.3684  0.92
2000 Schultz J, Copley RR, Doerks T, Ponting CP, Bork P. SMART: a web-based tool for the study of genetically mobile domains. Nucleic Acids Research. 28: 231-4. PMID 10592234  0.92
1999 Copley RR, Ponting CP, Bork P. Phospholipases A2 and Wnts are unlikely to share a common ancestor. Current Biology : Cb. 9: R718-9. PMID 10712041 DOI: 10.1016/S0960-9822(99)80466-7  0.92
1999 Ponting CP, Hofmann K, Bork P. A latrophilin/CL-1-like GPS domain in polycystin-1. Current Biology : Cb. 9: R585-8. PMID 10469603  1
1999 Ponting CP, Aravind L, Schultz J, Bork P, Koonin EV. Eukaryotic signalling domain homologues in archaea and bacteria. Ancient ancestry and horizontal gene transfer. Journal of Molecular Biology. 289: 729-45. PMID 10369758 DOI: 10.1006/jmbi.1999.2827  1
1999 Copley RR, Schultz J, Ponting CP, Bork P. Protein families in multicellular organisms. Current Opinion in Structural Biology. 9: 408-15. PMID 10361098 DOI: 10.1016/S0959-440X(99)80055-4  0.92
1999 Ponting CP, Bork P, Schultz J, Aravind L. No Sec7-homology domain in guanine-nucleotide-exchange factors that act on Ras and Rho. Trends in Biochemical Sciences. 24: 177-8. PMID 10322430  1
1999 Ponting CP, Schultz J, Milpetz F, Bork P. SMART: identification and annotation of domains from signalling and extracellular protein sequences. Nucleic Acids Research. 27: 229-32. PMID 9847187  1
1998 Kharrat A, Millevoi S, Baraldi E, Ponting CP, Bork P, Pastore A. Conformational stability studies of the pleckstrin DEP domain: definition of the domain boundaries. Biochimica Et Biophysica Acta. 1385: 157-64. PMID 9630596  1
1998 Schultz J, Milpetz F, Bork P, Ponting CP. SMART, a simple modular architecture research tool: identification of signaling domains. Proceedings of the National Academy of Sciences of the United States of America. 95: 5857-64. PMID 9600884  1
1997 Bork P, Schultz J, Ponting CP. Cytoplasmic signalling domains: the next generation. Trends in Biochemical Sciences. 22: 296-8. PMID 9270302  1
1997 Ponting CP, Cai YD, Bork P. The breast cancer gene product TSG101: a regulator of ubiquitination? Journal of Molecular Medicine (Berlin, Germany). 75: 467-9. PMID 9253709  1
1997 Schultz J, Ponting CP, Hofmann K, Bork P. SAM as a protein interaction domain involved in developmental regulation. Protein Science : a Publication of the Protein Society. 6: 249-53. PMID 9007998 DOI: 10.1002/pro.5560060128  1
1996 Ponting CP, Bork P. Pleckstrin's repeat performance: a novel domain in G-protein signaling? Trends in Biochemical Sciences. 21: 245-6. PMID 8755244  1
Show low-probability matches.