Chris P. Ponting - Publications

MRC Functional Genomics Unit University of Oxford, Oxford, United Kingdom 

167 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Bretherick AD, Canela-Xandri O, Joshi PK, Clark DW, Rawlik K, Boutin TS, Zeng Y, Amador C, Navarro P, Rudan I, Wright AF, Campbell H, Vitart V, Hayward C, Wilson JF, ... ... Ponting CP, et al. Linking protein to phenotype with Mendelian Randomization detects 38 proteins with causal roles in human diseases and traits. Plos Genetics. 16: e1008785. PMID 32628676 DOI: 10.1371/Journal.Pgen.1008785  0.314
2020 Batiuk MY, Martirosyan A, Wahis J, de Vin F, Marneffe C, Kusserow C, Koeppen J, Viana JF, Oliveira JF, Voet T, Ponting CP, Belgard TG, Holt MG. Identification of region-specific astrocyte subtypes at single cell resolution. Nature Communications. 11: 1220. PMID 32139688 DOI: 10.1038/S41467-019-14198-8  0.763
2019 Sirey TM, Roberts K, Haerty W, Bedoya-Reina O, Rogatti-Granados S, Tan JY, Li N, Heather LC, Carter RN, Cooper S, Finch AJ, Wills J, Morton NM, Marques AC, Ponting CP. The long non-coding RNA is a post transcriptional regulator of mitochondrial complex I catalytic activity. Elife. 8. PMID 31045494 DOI: 10.7554/Elife.45051  0.31
2019 Akay A, Jordan D, Navarro IC, Wrzesinski T, Ponting CP, Miska EA, Haerty W. Identification of functional long non-coding RNAs in C. elegans. Bmc Biology. 17: 14. PMID 30777050 DOI: 10.1186/S12915-019-0635-7  0.327
2019 Clifford H, Dulneva A, Ponting CP, Haerty W, Becker EBE. A gene expression signature in developing Purkinje cells predicts autism and intellectual disability co-morbidity status. Scientific Reports. 9: 485. PMID 30679692 DOI: 10.1038/S41598-018-37284-1  0.325
2018 Pavlaki I, Alammari F, Sun B, Clark N, Sirey T, Lee S, Woodcock DJ, Ponting CP, Szele FG, Vance KW. The long non-coding RNA promotes KAP1-dependent chromatin changes and regulates olfactory bulb neurogenesis. The Embo Journal. PMID 29661885 DOI: 10.15252/Embj.201798219  0.385
2017 Gallone G, Haerty W, Disanto G, Ramagopalan SV, Ponting CP, Berlanga-Taylor AJ. Identification of genetic variants affecting vitamin D receptor binding and associations with autoimmune disease. Human Molecular Genetics. PMID 28335003 DOI: 10.1093/Hmg/Ddx092  0.315
2017 Haerty W, Ponting C. Identification of functional non-coding transcribed sequences in Eukaryotes species Neuropeptides. 65: 141. DOI: 10.1016/J.Npep.2017.02.043  0.328
2016 Macaulay IC, Teng MJ, Haerty W, Kumar P, Ponting CP, Voet T. Separation and parallel sequencing of the genomes and transcriptomes of single cells using G&T-seq. Nature Protocols. 11: 2081-2103. PMID 27685099 DOI: 10.1038/Nprot.2016.138  0.368
2016 Chan MC, Ilott NE, Schödel J, Sims D, Tumber A, Lippl K, Mole DR, Pugh CW, Ratcliffe PJ, Ponting CP, Schofield CJ. Tuning the transcriptional response to hypoxia by inhibiting HIF prolyl- and asparaginyl-hydroxylases. The Journal of Biological Chemistry. PMID 27502280 DOI: 10.1074/Jbc.M116.749291  0.306
2016 Brazão TF, Johnson JS, Müller J, Heger A, Ponting CP, Tybulewicz VL. Long non-coding RNAs in B cell development and activation. Blood. PMID 27381906 DOI: 10.1182/Blood-2015-11-680843  0.309
2016 Fenwick AL, Kliszczak M, Cooper F, Murray J, Sanchez-Pulido L, Twigg SR, Goriely A, McGowan SJ, Miller KA, Taylor IB, Logan C, Bozdogan S, Danda S, Dixon J, ... ... Ponting CP, et al. Mutations in CDC45, Encoding an Essential Component of the Pre-initiation Complex, Cause Meier-Gorlin Syndrome and Craniosynostosis. American Journal of Human Genetics. PMID 27374770 DOI: 10.1016/J.Ajhg.2016.05.019  0.312
2016 Angermueller C, Clark SJ, Lee HJ, Macaulay IC, Teng MJ, Hu TX, Krueger F, Smallwood SA, Ponting CP, Voet T, Kelsey G, Stegle O, Reik W. Parallel single-cell sequencing links transcriptional and epigenetic heterogeneity. Nature Methods. PMID 26752769 DOI: 10.1038/Nmeth.3728  0.366
2015 Pembroke WG, Babbs A, Davies K, Ponting CP, Oliver PL. Temporal transcriptomics suggest that twin-peaking genes reset the clock. Elife. 4. PMID 26523393 DOI: 10.7554/Elife.10518  0.346
2015 Chung G, Rose AM, Petalcorin MI, Martin JS, Kessler Z, Sanchez-Pulido L, Ponting CP, Yanowitz JL, Boulton SJ. REC-1 and HIM-5 distribute meiotic crossovers and function redundantly in meiotic double-strand break formation in Caenorhabditis elegans. Genes & Development. 29: 1969-79. PMID 26385965 DOI: 10.1101/Gad.266056.115  0.349
2015 Wilson NK, Kent DG, Buettner F, Shehata M, Macaulay IC, Calero-Nieto FJ, Sánchez Castillo M, Oedekoven CA, Diamanti E, Schulte R, Ponting CP, Voet T, Caldas C, Stingl J, Green AR, et al. Combined Single-Cell Functional and Gene Expression Analysis Resolves Heterogeneity within Stem Cell Populations. Cell Stem Cell. 16: 712-24. PMID 26004780 DOI: 10.1016/J.Stem.2015.04.004  0.308
2015 Wehrspaun CC, Haerty W, Ponting CP. Microglia recapitulate a hematopoietic master regulator network in the aging human frontal cortex. Neurobiology of Aging. 36: 2443.e9-2443.e20. PMID 26002684 DOI: 10.1016/J.Neurobiolaging.2015.04.008  0.326
2015 Sims D, Ponting CP, Heger A. CGAT: a model for immersive personalized training in computational genomics. Briefings in Functional Genomics. PMID 25981124 DOI: 10.1093/Bfgp/Elv021  0.316
2015 Macaulay IC, Haerty W, Kumar P, Li YI, Hu TX, Teng MJ, Goolam M, Saurat N, Coupland P, Shirley LM, Smith M, Van der Aa N, Banerjee R, Ellis PD, Quail MA, ... ... Ponting CP, et al. G&T-seq: parallel sequencing of single-cell genomes and transcriptomes. Nature Methods. 12: 519-22. PMID 25915121 DOI: 10.1038/Nmeth.3370  0.377
2015 Haerty W, Ponting CP. Unexpected selection to retain high GC content and splicing enhancers within exons of multiexonic lncRNA loci. Rna (New York, N.Y.). 21: 333-46. PMID 25589248 DOI: 10.1261/Rna.047324.114  0.37
2015 Li YI, Sanchez-Pulido L, Haerty W, Ponting CP. RBFOX and PTBP1 proteins regulate the alternative splicing of micro-exons in human brain transcripts. Genome Research. 25: 1-13. PMID 25524026 DOI: 10.1101/Gr.181990.114  0.4
2015 Parkinson NJ, Roddis M, Ferneyhough B, Zhang G, Marsden AJ, Maslau S, Sanchez-Pearson Y, Barthlott T, Humphreys IR, Ladell K, Price DA, Ponting CP, Hollander G, Fischer MD. Violation of the 12/23 rule of genomic V(D)J recombination is common in lymphocytes. Genome Research. 25: 226-34. PMID 25367293 DOI: 10.1101/Gr.179770.114  0.392
2014 Li C, Zhang Y, Li J, Kong L, Hu H, Pan H, Xu L, Deng Y, Li Q, Jin L, Yu H, Chen Y, Liu B, Yang L, Liu S, ... ... Ponting CP, et al. Two Antarctic penguin genomes reveal insights into their evolutionary history and molecular changes related to the Antarctic environment. Gigascience. 3: 27. PMID 25671092 DOI: 10.1186/2047-217X-3-27  0.669
2014 Rajan P, Stockley J, Sudbery IM, Fleming JT, Hedley A, Kalna G, Sims D, Ponting CP, Heger A, Robson CN, McMenemin RM, Pedley ID, Leung HY. Identification of a candidate prognostic gene signature by transcriptome analysis of matched pre- and post-treatment prostatic biopsies from patients with advanced prostate cancer. Bmc Cancer. 14: 977. PMID 25519703 DOI: 10.1186/1471-2407-14-977  0.316
2014 Tan JY, Vance KW, Varela MA, Sirey T, Watson LM, Curtis HJ, Marinello M, Alves S, Steinkraus BR, Cooper S, Nesterova T, Brockdorff N, Fulga TA, Brice A, Sittler A, ... ... Ponting CP, et al. Cross-talking noncoding RNAs contribute to cell-specific neurodegeneration in SCA7. Nature Structural & Molecular Biology. 21: 955-61. PMID 25306109 DOI: 10.1038/Nsmb.2902  0.33
2014 Oliver PL, Chodroff RA, Gosal A, Edwards B, Cheung AF, Gomez-Rodriguez J, Elliot G, Garrett LJ, Lickiss T, Szele F, Green ED, Molnár Z, Ponting CP. Disruption of Visc-2, a Brain-Expressed Conserved Long Noncoding RNA, Does Not Elicit an Overt Anatomical or Behavioral Phenotype. Cerebral Cortex (New York, N.Y. : 1991). PMID 25209608 DOI: 10.1093/Cercor/Bhu196  0.369
2014 Brawand D, Wagner CE, Li YI, Malinsky M, Keller I, Fan S, Simakov O, Ng AY, Lim ZW, Bezault E, Turner-Maier J, Johnson J, Alcazar R, Noh HJ, Russell P, ... ... Ponting CP, et al. The genomic substrate for adaptive radiation in African cichlid fish. Nature. 513: 375-81. PMID 25186727 DOI: 10.1038/Nature13726  0.382
2014 White SA, Buscaino A, Sanchez-Pulido L, Ponting CP, Nowicki MW, Allshire RC. The RFTS domain of Raf2 is required for Cul4 interaction and heterochromatin integrity in fission yeast. Plos One. 9: e104161. PMID 25090107 DOI: 10.1371/Journal.Pone.0104161  0.33
2014 Rainger J, Pehlivan D, Johansson S, Bengani H, Sanchez-Pulido L, Williamson KA, Ture M, Barker H, Rosendahl K, Spranger J, Horn D, Meynert A, Floyd JA, Prescott T, Anderson CA, ... ... Ponting CP, et al. Monoallelic and biallelic mutations in MAB21L2 cause a spectrum of major eye malformations. American Journal of Human Genetics. 94: 915-23. PMID 24906020 DOI: 10.1016/J.Ajhg.2014.05.005  0.31
2014 Booth DG, Takagi M, Sanchez-Pulido L, Petfalski E, Vargiu G, Samejima K, Imamoto N, Ponting CP, Tollervey D, Earnshaw WC, Vagnarelli P. Ki-67 is a PP1-interacting protein that organises the mitotic chromosome periphery. Elife. 3: e01641. PMID 24867636 DOI: 10.7554/Elife.01641  0.302
2014 Lu M, Zak J, Chen S, Sanchez-Pulido L, Severson DT, Endicott J, Ponting CP, Schofield CJ, Lu X. A code for RanGDP binding in ankyrin repeats defines a nuclear import pathway. Cell. 157: 1130-45. PMID 24855949 DOI: 10.1016/J.Cell.2014.05.006  0.328
2014 Marques AC, Ponting CP. Intergenic lncRNAs and the evolution of gene expression. Current Opinion in Genetics & Development. 27: 48-53. PMID 24852186 DOI: 10.1016/J.Gde.2014.03.009  0.426
2014 Haerty W, Ponting CP. No gene in the genome makes sense except in the light of evolution. Annual Review of Genomics and Human Genetics. 15: 71-92. PMID 24773316 DOI: 10.1146/Annurev-Genom-090413-025621  0.415
2014 Wehrspaun CC, Ponting CP, Marques AC. Brain-expressed 3'UTR extensions strengthen miRNA cross-talk between ion channel/transporter encoding mRNAs. Frontiers in Genetics. 5: 41. PMID 24616735 DOI: 10.3389/Fgene.2014.00041  0.304
2014 Vance KW, Sansom SN, Lee S, Chalei V, Kong L, Cooper SE, Oliver PL, Ponting CP. The long non-coding RNA Paupar regulates the expression of both local and distal genes. The Embo Journal. 33: 296-311. PMID 24488179 DOI: 10.1002/Embj.201386225  0.375
2014 Sims D, Ilott NE, Sansom SN, Sudbery IM, Johnson JS, Fawcett KA, Berlanga-Taylor AJ, Luna-Valero S, Ponting CP, Heger A. CGAT: computational genomics analysis toolkit. Bioinformatics (Oxford, England). 30: 1290-1. PMID 24395753 DOI: 10.1093/Bioinformatics/Btt756  0.381
2014 Bassett AR, Tibbit C, Ponting CP, Liu JL. Mutagenesis and homologous recombination in Drosophila cell lines using CRISPR/Cas9. Biology Open. 3: 42-9. PMID 24326186 DOI: 10.1242/Bio.20137120  0.343
2014 Rajan P, Sudbery IM, Villasevil ME, Mui E, Fleming J, Davis M, Ahmad I, Edwards J, Sansom OJ, Sims D, Ponting CP, Heger A, McMenemin RM, Pedley ID, Leung HY. Next-generation sequencing of advanced prostate cancer treated with androgen-deprivation therapy. European Urology. 66: 32-9. PMID 24054872 DOI: 10.1016/J.Eururo.2013.08.011  0.304
2013 Marques AC, Hughes J, Graham B, Kowalczyk MS, Higgs DR, Ponting CP. Chromatin signatures at transcriptional start sites separate two equally populated yet distinct classes of intergenic long noncoding RNAs. Genome Biology. 14: R131. PMID 24289259 DOI: 10.1186/Gb-2013-14-11-R131  0.353
2013 Belgard TG, Montiel JF, Wang WZ, García-Moreno F, Margulies EH, Ponting CP, Molnár Z. Adult pallium transcriptomes surprise in not reflecting predicted homologies across diverse chicken and mouse pallial sectors. Proceedings of the National Academy of Sciences of the United States of America. 110: 13150-5. PMID 23878249 DOI: 10.1073/Pnas.1307444110  0.77
2013 Young RS, Ponting CP. Identification and function of long non-coding RNAs. Essays in Biochemistry. 54: 113-26. PMID 23829531 DOI: 10.1042/Bse0540113  0.368
2013 Bassett AR, Tibbit C, Ponting CP, Liu JL. Highly efficient targeted mutagenesis of Drosophila with the CRISPR/Cas9 system. Cell Reports. 4: 220-8. PMID 23827738 DOI: 10.1016/J.Celrep.2013.06.020  0.311
2013 Heger A, Webber C, Goodson M, Ponting CP, Lunter G. GAT: a simulation framework for testing the association of genomic intervals. Bioinformatics (Oxford, England). 29: 2046-8. PMID 23782611 DOI: 10.1093/Bioinformatics/Btt343  0.365
2013 Noh HJ, Ponting CP, Boulding HC, Meader S, Betancur C, Buxbaum JD, Pinto D, Marshall CR, Lionel AC, Scherer SW, Webber C. Network topologies and convergent aetiologies arising from deletions and duplications observed in individuals with autism. Plos Genetics. 9: e1003523. PMID 23754953 DOI: 10.1371/Journal.Pgen.1003523  0.32
2013 Babbs C, Roberts NA, Sanchez-Pulido L, McGowan SJ, Ahmed MR, Brown JM, Sabry MA, Bentley DR, McVean GA, Donnelly P, Gileadi O, Ponting CP, Higgs DR, Buckle VJ. Homozygous mutations in a predicted endonuclease are a novel cause of congenital dyserythropoietic anemia type I. Haematologica. 98: 1383-7. PMID 23716552 DOI: 10.3324/Haematol.2013.089490  0.329
2013 Haerty W, Ponting CP. Mutations within lncRNAs are effectively selected against in fruitfly but not in human. Genome Biology. 14: R49. PMID 23710818 DOI: 10.1186/Gb-2013-14-5-R49  0.378
2013 Doolittle WF, Fraser P, Gerstein MB, Graveley BR, Henikoff S, Huttenhower C, Oshlack A, Ponting CP, Rinn JL, Schatz MC, Ule J, Weigel D, Weinstock GM. Sixty years of genome biology. Genome Biology. 14: 113. PMID 23651518 DOI: 10.1186/Gb-2013-14-4-113  0.341
2013 Amemiya CT, Alföldi J, Lee AP, Fan S, Philippe H, Maccallum I, Braasch I, Manousaki T, Schneider I, Rohner N, Organ C, Chalopin D, Smith JJ, Robinson M, Dorrington RA, ... ... Ponting CP, et al. The African coelacanth genome provides insights into tetrapod evolution. Nature. 496: 311-6. PMID 23598338 DOI: 10.1038/Nature12027  0.425
2013 Li YI, Kong L, Ponting CP, Haerty W. Rapid evolution of Beta-keratin genes contribute to phenotypic differences that distinguish turtles and birds from other reptiles. Genome Biology and Evolution. 5: 923-33. PMID 23576313 DOI: 10.1093/Gbe/Evt060  0.353
2013 Shaffer HB, Minx P, Warren DE, Shedlock AM, Thomson RC, Valenzuela N, Abramyan J, Amemiya CT, Badenhorst D, Biggar KK, Borchert GM, Botka CW, Bowden RM, Braun EL, Bronikowski AM, ... ... Ponting CP, et al. The western painted turtle genome, a model for the evolution of extreme physiological adaptations in a slowly evolving lineage. Genome Biology. 14: R28. PMID 23537068 DOI: 10.1186/Gb-2013-14-3-R28  0.745
2013 Long HK, Sims D, Heger A, Blackledge NP, Kutter C, Wright ML, Grützner F, Odom DT, Patient R, Ponting CP, Klose RJ. Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates. Elife. 2: e00348. PMID 23467541 DOI: 10.7554/Elife.00348  0.303
2013 Rands CM, Darling A, Fujita M, Kong L, Webster MT, Clabaut C, Emes RD, Heger A, Meader S, Hawkins MB, Eisen MB, Teiling C, Affourtit J, Boese B, Grant PR, ... ... Ponting CP, et al. Insights into the evolution of Darwin's finches from comparative analysis of the Geospiza magnirostris genome sequence. Bmc Genomics. 14: 95. PMID 23402223 DOI: 10.1186/1471-2164-14-95  0.703
2012 Farcas AM, Blackledge NP, Sudbery I, Long HK, McGouran JF, Rose NR, Lee S, Sims D, Cerase A, Sheahan TW, Koseki H, Brockdorff N, Ponting CP, Kessler BM, Klose RJ. KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands. Elife. 1: e00205. PMID 23256043 DOI: 10.7554/Elife.00205  0.356
2012 Marques AC, Tan J, Lee S, Kong L, Heger A, Ponting CP. Evidence for conserved post-transcriptional roles of unitary pseudogenes and for frequent bifunctionality of mRNAs. Genome Biology. 13: R102. PMID 23153069 DOI: 10.1186/Gb-2012-13-11-R102  0.362
2012 Goodson M, Rust MB, Witke W, Bannerman D, Mott R, Ponting CP, Flint J. Cofilin-1: a modulator of anxiety in mice. Plos Genetics. 8: e1002970. PMID 23055942 DOI: 10.1371/Journal.Pgen.1002970  0.325
2012 Ponting CP, Oliver PL. Brain, know thy transcriptome, know thyself. Neuron. 75: 543-5. PMID 22920245 DOI: 10.1016/J.Neuron.2012.08.005  0.304
2012 Kutter C, Watt S, Stefflova K, Wilson MD, Goncalves A, Ponting CP, Odom DT, Marques AC. Rapid turnover of long noncoding RNAs and the evolution of gene expression. Plos Genetics. 8: e1002841. PMID 22844254 DOI: 10.1371/Journal.Pgen.1002841  0.414
2012 Prüfer K, Munch K, Hellmann I, Akagi K, Miller JR, Walenz B, Koren S, Sutton G, Kodira C, Winer R, Knight JR, Mullikin JC, Meader SJ, Ponting CP, Lunter G, et al. The bonobo genome compared with the chimpanzee and human genomes. Nature. 486: 527-31. PMID 22722832 DOI: 10.1038/Nature11128  0.382
2012 Nellåker C, Keane TM, Yalcin B, Wong K, Agam A, Belgard TG, Flint J, Adams DJ, Frankel WN, Ponting CP. The genomic landscape shaped by selection on transposable elements across 18 mouse strains. Genome Biology. 13: R45. PMID 22703977 DOI: 10.1186/Gb-2012-13-6-R45  0.795
2012 Kowalczyk MS, Hughes JR, Babbs C, Sanchez-Pulido L, Szumska D, Sharpe JA, Sloane-Stanley JA, Morriss-Kay GM, Smoot LB, Roberts AE, Watkins H, Bhattacharya S, Gibbons RJ, Ponting CP, Wood WG, et al. Nprl3 is required for normal development of the cardiovascular system. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 23: 404-15. PMID 22538705 DOI: 10.1007/S00335-012-9398-Y  0.376
2012 Danecek P, Nellåker C, McIntyre RE, Buendia-Buendia JE, Bumpstead S, Ponting CP, Flint J, Durbin R, Keane TM, Adams DJ. High levels of RNA-editing site conservation amongst 15 laboratory mouse strains. Genome Biology. 13: 26. PMID 22524474 DOI: 10.1186/Gb-2012-13-4-R26  0.382
2012 Young RS, Marques AC, Tibbit C, Haerty W, Bassett AR, Liu JL, Ponting CP. Identification and properties of 1,119 candidate lincRNA loci in the Drosophila melanogaster genome. Genome Biology and Evolution. 4: 427-42. PMID 22403033 DOI: 10.1093/Gbe/Evs020  0.435
2012 Scally A, Dutheil JY, Hillier LW, Jordan GE, Goodhead I, Herrero J, Hobolth A, Lappalainen T, Mailund T, Marques-Bonet T, McCarthy S, Montgomery SH, Schwalie PC, Tang YA, Ward MC, ... ... Ponting CP, et al. Insights into hominid evolution from the gorilla genome sequence. Nature. 483: 169-75. PMID 22398555 DOI: 10.1038/Nature10842  0.428
2012 Parkinson NJ, Maslau S, Ferneyhough B, Zhang G, Gregory L, Buck D, Ragoussis J, Ponting CP, Fischer MD. Preparation of high-quality next-generation sequencing libraries from picogram quantities of target DNA. Genome Research. 22: 125-33. PMID 22090378 DOI: 10.1101/Gr.124016.111  0.371
2012 Axelsson E, Webster MT, Ratnakumar A, Ponting CP, Lindblad-Toh K. Death of PRDM9 coincides with stabilization of the recombination landscape in the dog genome. Genome Research. 22: 51-63. PMID 22006216 DOI: 10.1101/Gr.124123.111  0.411
2011 Keane TM, Goodstadt L, Danecek P, White MA, Wong K, Yalcin B, Heger A, Agam A, Slater G, Goodson M, Furlotte NA, Eskin E, NellÃ¥ker C, Whitley H, Cleak J, ... ... Ponting CP, et al. Mouse genomic variation and its effect on phenotypes and gene regulation. Nature. 477: 289-94. PMID 21921910 DOI: 10.1038/Nature10413  0.799
2011 Alföldi J, Di Palma F, Grabherr M, Williams C, Kong L, Mauceli E, Russell P, Lowe CB, Glor RE, Jaffe JD, Ray DA, Boissinot S, Shedlock AM, Botka C, Castoe TA, ... ... Ponting CP, et al. The genome of the green anole lizard and a comparative analysis with birds and mammals. Nature. 477: 587-91. PMID 21881562 DOI: 10.1038/Nature10390  0.739
2011 Ponting CP, Hardison RC. What fraction of the human genome is functional? Genome Research. 21: 1769-76. PMID 21875934 DOI: 10.1101/Gr.116814.110  0.39
2011 Belgard TG, Marques AC, Oliver PL, Abaan HO, Sirey TM, Hoerder-Suabedissen A, García-Moreno F, Molnár Z, Margulies EH, Ponting CP. A transcriptomic atlas of mouse neocortical layers. Neuron. 71: 605-16. PMID 21867878 DOI: 10.1016/J.Neuron.2011.06.039  0.763
2011 Wong ES, Papenfuss AT, Heger A, Hsu AL, Ponting CP, Miller RD, Fenelon JC, Renfree MB, Gibbs RA, Belov K. Transcriptomic analysis supports similar functional roles for the two thymuses of the tammar wallaby. Bmc Genomics. 12: 420. PMID 21854594 DOI: 10.1186/1471-2164-12-420  0.34
2011 Fujita MK, Edwards SV, Ponting CP. The Anolis lizard genome: an amniote genome without isochores. Genome Biology and Evolution. 3: 974-84. PMID 21795750 DOI: 10.1093/Gbe/Evr072  0.741
2011 Clark MB, Amaral PP, Schlesinger FJ, Dinger ME, Taft RJ, Rinn JL, Ponting CP, Stadler PF, Morris KV, Morillon A, Rozowsky JS, Gerstein MB, Wahlestedt C, Hayashizaki Y, Carninci P, et al. The reality of pervasive transcription. Plos Biology. 9: e1000625; discussion. PMID 21765801 DOI: 10.1371/Journal.Pbio.1000625  0.356
2011 Mills RE, Pittard WS, Mullaney JM, Farooq U, Creasy TH, Mahurkar AA, Kemeza DM, Strassler DS, Ponting CP, Webber C, Devine SE. Natural genetic variation caused by small insertions and deletions in the human genome. Genome Research. 21: 830-9. PMID 21460062 DOI: 10.1101/Gr.115907.110  0.364
2011 Blair HJ, Tompson S, Liu YN, Campbell J, MacArthur K, Ponting CP, Ruiz-Perez VL, Goodship JA. Evc2 is a positive modulator of Hedgehog signalling that interacts with Evc at the cilia membrane and is also found in the nucleus. Bmc Biology. 9: 14. PMID 21356043 DOI: 10.1186/1741-7007-9-14  0.312
2011 Locke DP, Hillier LW, Warren WC, Worley KC, Nazareth LV, Muzny DM, Yang SP, Wang Z, Chinwalla AT, Minx P, Mitreva M, Cook L, Delehaunty KD, Fronick C, Schmidt H, ... ... Ponting CP, et al. Comparative and demographic analysis of orang-utan genomes. Nature. 469: 529-33. PMID 21270892 DOI: 10.1038/Nature09687  0.395
2011 Shaikh TH, Haldeman-Englert C, Geiger EA, Ponting CP, Webber C. Genes and biological processes commonly disrupted in rare and heterogeneous developmental delay syndromes. Human Molecular Genetics. 20: 880-93. PMID 21147756 DOI: 10.1093/Hmg/Ddq527  0.354
2010 Ponting CP, Belgard TG. Transcribed dark matter: meaning or myth? Human Molecular Genetics. 19: R162-8. PMID 20798109 DOI: 10.1093/Hmg/Ddq362  0.792
2010 Ramagopalan SV, Heger A, Berlanga AJ, Maugeri NJ, Lincoln MR, Burrell A, Handunnetthi L, Handel AE, Disanto G, Orton SM, Watson CT, Morahan JM, Giovannoni G, Ponting CP, Ebers GC, et al. A ChIP-seq defined genome-wide map of vitamin D receptor binding: associations with disease and evolution. Genome Research. 20: 1352-60. PMID 20736230 DOI: 10.1101/Gr.107920.110  0.336
2010 Chodroff RA, Goodstadt L, Sirey TM, Oliver PL, Davies KE, Green ED, Molnár Z, Ponting CP. Long noncoding RNA genes: conservation of sequence and brain expression among diverse amniotes. Genome Biology. 11: R72. PMID 20624288 DOI: 10.1186/Gb-2010-11-7-R72  0.42
2010 Sanchez-Pulido L, Diffley JF, Ponting CP. Homology explains the functional similarities of Treslin/Ticrr and Sld3. Current Biology : Cb. 20: R509-10. PMID 20620901 DOI: 10.1016/J.Cub.2010.05.021  0.308
2010 Nam K, Mugal C, Nabholz B, Schielzeth H, Wolf JB, Backström N, Künstner A, Balakrishnan CN, Heger A, Ponting CP, Clayton DF, Ellegren H. Molecular evolution of genes in avian genomes. Genome Biology. 11: R68. PMID 20573239 DOI: 10.1186/Gb-2010-11-6-R68  0.449
2010 Pinto D, Pagnamenta AT, Klei L, Anney R, Merico D, Regan R, Conroy J, Magalhaes TR, Correia C, Abrahams BS, Almeida J, Bacchelli E, Bader GD, Bailey AJ, Baird G, ... ... Ponting CP, et al. Functional impact of global rare copy number variation in autism spectrum disorders. Nature. 466: 368-72. PMID 20531469 DOI: 10.1038/Nature09146  0.494
2010 Hehir-Kwa JY, Wieskamp N, Webber C, Pfundt R, Brunner HG, Gilissen C, de Vries BB, Ponting CP, Veltman JA. Accurate distinction of pathogenic from benign CNVs in mental retardation. Plos Computational Biology. 6: e1000752. PMID 20421931 DOI: 10.1371/Journal.Pcbi.1000752  0.373
2010 Warren WC, Clayton DF, Ellegren H, Arnold AP, Hillier LW, Künstner A, Searle S, White S, Vilella AJ, Fairley S, Heger A, Kong L, Ponting CP, Jarvis ED, Mello CV, et al. The genome of a songbird. Nature. 464: 757-62. PMID 20360741 DOI: 10.1038/Nature08819  0.582
2010 Murton BL, Chin WL, Ponting CP, Itzhaki LS. Characterising the binding specificities of the subunits associated with the KMT2/Set1 histone lysine methyltransferase. Journal of Molecular Biology. 398: 481-8. PMID 20347846 DOI: 10.1016/J.Jmb.2010.03.036  0.322
2010 Kong L, Lovell PV, Heger A, Mello CV, Ponting CP. Accelerated evolution of PAK3- and PIM1-like kinase gene families in the zebra finch, Taeniopygia guttata. Molecular Biology and Evolution. 27: 1923-34. PMID 20237222 DOI: 10.1093/Molbev/Msq080  0.431
2010 Bayne EH, White SA, Kagansky A, Bijos DA, Sanchez-Pulido L, Hoe KL, Kim DU, Park HO, Ponting CP, Rappsilber J, Allshire RC. Stc1: a critical link between RNAi and chromatin modification required for heterochromatin integrity. Cell. 140: 666-77. PMID 20211136 DOI: 10.1016/J.Cell.2010.01.038  0.306
2010 Noh HJ, Marshall CR, Pinto D, Scherer SW, Ponting CP, Webber C. Candidate genes and biological processes in de novo CNVs from autistic individuals Genome Biology. 11: O9. DOI: 10.1186/Gb-2010-11-S1-O9  0.331
2009 Oliver PL, Goodstadt L, Bayes JJ, Birtle Z, Roach KC, Phadnis N, Beatson SA, Lunter G, Malik HS, Ponting CP. Accelerated evolution of the Prdm9 speciation gene across diverse metazoan taxa. Plos Genetics. 5: e1000753. PMID 19997497 DOI: 10.1371/Journal.Pgen.1000753  0.383
2009 Marques AC, Ponting CP. Catalogues of mammalian long noncoding RNAs: Modest conservation and incompleteness Genome Biology. 10. PMID 19895688 DOI: 10.1186/Gb-2009-10-11-R124  0.387
2009 Webber C, Hehir-Kwa JY, Nguyen DQ, de Vries BB, Veltman JA, Ponting CP. Forging links between human mental retardation-associated CNVs and mouse gene knockout models. Plos Genetics. 5: e1000531. PMID 19557186 DOI: 10.1371/Journal.Pgen.1000531  0.336
2009 Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X, Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y, Meric P, Maglott D, Birtle Z, ... ... Ponting CP, et al. Lineage-specific biology revealed by a finished genome assembly of the mouse. Plos Biology. 7: e1000112. PMID 19468303 DOI: 10.1371/Journal.Pbio.1000112  0.45
2009 Heger A, Ponting CP, Holmes I. Accurate estimation of gene evolutionary rates using XRATE, with an application to transmembrane proteins. Molecular Biology and Evolution. 26: 1715-21. PMID 19380462 DOI: 10.1093/Molbev/Msp080  0.327
2008 Abd El-Aziz MM, Barragan I, O'Driscoll CA, Goodstadt L, Prigmore E, Borrego S, Mena M, Pieras JI, El-Ashry MF, Safieh LA, Shah A, Cheetham ME, Carter NP, Chakarova C, Ponting CP, et al. EYS, encoding an ortholog of Drosophila spacemaker, is mutated in autosomal recessive retinitis pigmentosa. Nature Genetics. 40: 1285-7. PMID 18836446 DOI: 10.1038/Ng.241  0.327
2008 Warren WC, Hillier LW, Marshall Graves JA, Birney E, Ponting CP, Grützner F, Belov K, Miller W, Clarke L, Chinwalla AT, Yang SP, Heger A, Locke DP, Miethke P, Waters PD, et al. Genome analysis of the platypus reveals unique signatures of evolution. Nature. 453: 175-83. PMID 18464734 DOI: 10.1038/Nature06936  0.436
2008 Whittington CM, Papenfuss AT, Bansal P, Torres AM, Wong ES, Deakin JE, Graves T, Alsop A, Schatzkamer K, Kremitzki C, Ponting CP, Temple-Smith P, Warren WC, Kuchel PW, Belov K. Defensins and the convergent evolution of platypus and reptile venom genes. Genome Research. 18: 986-94. PMID 18463304 DOI: 10.1101/Gr.7149808  0.387
2008 Bakrania P, Efthymiou M, Klein JC, Salt A, Bunyan DJ, Wyatt A, Ponting CP, Martin A, Williams S, Lindley V, Gilmore J, Restori M, Robson AG, Neveu MM, Holder GE, et al. Mutations in BMP4 cause eye, brain, and digit developmental anomalies: overlap between the BMP4 and hedgehog signaling pathways. American Journal of Human Genetics. 82: 304-19. PMID 18252212 DOI: 10.1016/J.Ajhg.2007.09.023  0.33
2008 Heger A, Ponting CP. OPTIC: Orthologous and paralogous transcripts in clades Nucleic Acids Research. 36: D267-D270. PMID 17933761 DOI: 10.1093/Nar/Gkm852  0.392
2007 Heger A, Ponting CP. Variable strength of translational selection among 12 Drosophila species Genetics. 177: 1337-1348. PMID 18039870 DOI: 10.1534/Genetics.107.070466  0.365
2007 Clark AG, Eisen MB, Smith DR, Bergman CM, Oliver B, Markow TA, Kaufman TC, Kellis M, Gelbart W, Iyer VN, Pollard DA, Sackton TB, Larracuente AM, Singh ND, ... ... Ponting CP, et al. Evolution of genes and genomes on the Drosophila phylogeny. Nature. 450: 203-18. PMID 17994087 DOI: 10.1038/Nature06341  0.432
2007 Heger A, Ponting CP. Evolutionary rate analyses of orthologs and paralogs from 12 Drosophila genomes Genome Research. 17: 1837-1849. PMID 17989258 DOI: 10.1101/Gr.6249707  0.416
2007 Chakarova CF, Papaioannou MG, Khanna H, Lopez I, Waseem N, Shah A, Theis T, Friedman J, Maubaret C, Bujakowska K, Veraitch B, Abd El-Aziz MM, Prescott de Q, Parapuram SK, Bickmore WA, ... ... Ponting CP, et al. Mutations in TOPORS cause autosomal dominant retinitis pigmentosa with perivascular retinal pigment epithelium atrophy. American Journal of Human Genetics. 81: 1098-103. PMID 17924349 DOI: 10.1086/521953  0.322
2007 Mikkelsen TS, Wakefield MJ, Aken B, Amemiya CT, Chang JL, Duke S, Garber M, Gentles AJ, Goodstadt L, Heger A, Jurka J, Kamal M, Mauceli E, Searle SM, Sharpe T, ... ... Ponting CP, et al. Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences. Nature. 447: 167-77. PMID 17495919 DOI: 10.1038/Nature05805  0.432
2007 Goodstadt L, Heger A, Webber C, Ponting CP. An analysis of the gene complement of a marsupial, Monodelphis domestica: evolution of lineage-specific genes and giant chromosomes. Genome Research. 17: 969-81. PMID 17495010 DOI: 10.1101/Gr.6093907  0.367
2005 Lindblad-Toh K, Wade CM, Mikkelsen TS, Karlsson EK, Jaffe DB, Kamal M, Clamp M, Chang JL, Kulbokas EJ, Zody MC, Mauceli E, Xie X, Breen M, Wayne RK, Ostrander EA, ... Ponting CP, et al. Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature. 438: 803-19. PMID 16341006 DOI: 10.1038/Nature04338  0.409
2005 Coward K, Ponting CP, Chang HY, Hibbitt O, Savolainen P, Jones KT, Parrington J. Phospholipase Czeta, the trigger of egg activation in mammals, is present in a non-mammalian species. Reproduction (Cambridge, England). 130: 157-63. PMID 16049153 DOI: 10.1530/Rep.1.00707  0.322
2005 Laukaitis CM, Dlouhy SR, Emes RD, Ponting CP, Karn RC. Diverse spatial, temporal, and sexual expression of recently duplicated androgen-binding protein genes in Mus musculus. Bmc Evolutionary Biology. 5: 40. PMID 16018816 DOI: 10.1186/1471-2148-5-40  0.342
2005 Ponting C, Jackson AP. Evolution of primary microcephaly genes and the enlargement of primate brains Current Opinion in Genetics and Development. 15: 241-248. PMID 15917198 DOI: 10.1016/J.Gde.2005.04.009  0.33
2005 Mulder NJ, Apweiler R, Attwood TK, Bairoch A, Bateman A, Binns D, Bradley P, Bork P, Bucher P, Cerutti L, Copley R, Courcelle E, Das U, Durbin R, Fleischmann W, ... ... Ponting CP, et al. InterPro, progress and status in 2005. Nucleic Acids Research. 33: D201-5. PMID 15608177 DOI: 10.1093/Nar/Gki106  0.496
2004 Emes RD, Riley MC, Laukaitis CM, Goodstadt L, Karn RC, Ponting CP. Comparative evolutionary genomics of androgen-binding protein genes. Genome Research. 14: 1516-29. PMID 15256509 DOI: 10.1101/Gr.2540304  0.431
2004 Huang H, Winter EE, Wang H, Weinstock KG, Xing H, Goodstadt L, Stenson PD, Cooper DN, Smith D, Albà MM, Ponting CP, Fechtel K. Evolutionary conservation and selection of human disease gene orthologs in the rat and mouse genomes Genome Biology. 5: R47. PMID 15239832 DOI: 10.1186/Gb-2004-5-7-R47  0.346
2004 Taylor MS, Ponting CP, Copley RR. Occurrence and consequences of coding sequence insertions and deletions in Mammalian genomes. Genome Research. 14: 555-66. PMID 15059996 DOI: 10.1101/Gr.1977804  0.399
2004 Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, ... ... Ponting CP, et al. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Nature. 428: 493-521. PMID 15057822 DOI: 10.1038/Nature02426  0.555
2004 Zimdahl H, Nyakatura G, Brandt P, Schulz H, Hummel O, Fartmann B, Brett D, Droege M, Monti J, Lee YA, Sun Y, Zhao S, Winter EE, Ponting CP, Chen Y, et al. A SNP map of the rat genome generated from cDNA sequences. Science (New York, N.Y.). 303: 807. PMID 14764869 DOI: 10.1126/Science.1092427  0.355
2004 Letunic I, Copley RR, Schmidt S, Ciccarelli FD, Doerks T, Schultz J, Ponting CP, Bork P. SMART 4.0: towards genomic data integration. Nucleic Acids Research. 32: D142-4. PMID 14681379 DOI: 10.1093/Nar/Gkh088  0.552
2004 Smith L, Van Hateren N, Willan J, Romero R, Blanco G, Siggers P, Walsh J, Banerjee R, Denny P, Ponting C, Greenfield A. Candidate testis-determining gene, Maestro (Mro), encodes a novel HEAT repeat protein. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 227: 600-7. PMID 12889070 DOI: 10.1002/Dvdy.10342  0.36
2003 Copley RR, Goodstadt L, Ponting C. Eukaryotic domain evolution inferred from genome comparisons. Current Opinion in Genetics & Development. 13: 623-8. PMID 14638325 DOI: 10.1016/J.Gde.2003.10.004  0.394
2003 Allen M, Heinzmann A, Noguchi E, Abecasis G, Broxholme J, Ponting CP, Bhattacharyya S, Tinsley J, Zhang Y, Holt R, Yvonne Jones E, Lench N, Carey A, Jones H, Dickens NJ, et al. Positional cloning of a novel gene influencing asthma from Chromosome 2q14 Nature Genetics. 35: 258-263. PMID 14566338 DOI: 10.1038/Ng1256  0.304
2003 Hartmann-Petersen R, Semple CAM, Ponting CP, Hendil KB, Gordon C. UBA domain containing proteins in fission yeast International Journal of Biochemistry and Cell Biology. 35: 629-636. PMID 12672455 DOI: 10.1016/S1357-2725(02)00393-X  0.343
2003 Maurer-Stroh S, Dickens NJ, Hughes-Davies L, Kouzarides T, Eisenhaber F, Ponting CP. The Tudor domain 'Royal Family': Tudor, plant Agenet, Chromo, PWWP and MBT domains. Trends in Biochemical Sciences. 28: 69-74. PMID 12575993 DOI: 10.1016/S0968-0004(03)00004-5  0.309
2003 Guigo R, Dermitzakis ET, Agarwal P, Ponting CP, Parra G, Reymond A, Abril JF, Keibler E, Lyle R, Ucla C, Antonarakis SE, Brent MR. Comparison of mouse and human genomes followed by experimental verification yields an estimated 1,019 additional genes. Proceedings of the National Academy of Sciences of the United States of America. 100: 1140-5. PMID 12552088 DOI: 10.1073/Pnas.0337561100  0.444
2003 Mulder NJ, Apweiler R, Attwood TK, Bairoch A, Barrell D, Bateman A, Binns D, Biswas M, Bradley P, Bork P, Bucher P, Copley RR, Courcelle E, Das U, Durbin R, ... ... Ponting CP, et al. The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Research. 31: 315-8. PMID 12520011 DOI: 10.1093/Nar/Gkg046  0.484
2002 Waterston RH, Lindblad-Toh K, Birney E, Rogers J, Abril JF, Agarwal P, Agarwala R, Ainscough R, Alexandersson M, An P, Antonarakis SE, Attwood J, Baertsch R, Bailey J, ... ... Ponting CP, et al. Initial sequencing and comparative analysis of the mouse genome. Nature. 420: 520-62. PMID 12466850 DOI: 10.1038/Nature01262  0.561
2002 Copley RR, Ponting CP, Schultz J, Bork P. Sequence analysis of multidomain proteins: past perspectives and future directions. Advances in Protein Chemistry. 61: 75-98. PMID 12461821 DOI: 10.1016/S0065-3233(02)61002-2  0.497
2002 Mulder NJ, Apweiler R, Attwood TK, Bairoch A, Bateman A, Binns D, Biswas M, Bradley P, Bork P, Bucher P, Copley R, Courcelle E, Durbin R, Falquet L, Fleischmann W, ... ... Ponting CP, et al. InterPro: an integrated documentation resource for protein families, domains and functional sites. Briefings in Bioinformatics. 3: 225-35. PMID 12230031 DOI: 10.1093/Bib/3.3.225  0.534
2002 Vargas JD, Culetto E, Ponting CP, Miguel-Aliaga I, Davies KE, Sattelle DB. Cloning and developmental expression analysis of ltd-1, the Caenorhabditis elegans homologue of the mouse kyphoscoliosis (ky) gene. Mechanisms of Development. 117: 289-92. PMID 12204272 DOI: 10.1016/S0925-4773(02)00182-X  0.358
2002 Mott R, Schultz J, Bork P, Ponting CP. Predicting protein cellular localization using a domain projection method. Genome Research. 12: 1168-74. PMID 12176924 DOI: 10.1101/Gr.96802  0.477
2002 Ponting CP, Hutton M, Nyborg A, Baker M, Jansen K, Golde TE. Identification of a novel family of presenilin homologues. Human Molecular Genetics. 11: 1037-44. PMID 11978763 DOI: 10.1093/Hmg/11.9.1037  0.354
2002 Doerks T, Copley RR, Schultz J, Ponting CP, Bork P. Systematic identification of novel protein domain families associated with nuclear functions. Genome Research. 12: 47-56. PMID 11779830 DOI: 10.1101/Gr.203201  0.493
2002 Letunic I, Goodstadt L, Dickens NJ, Doerks T, Schultz J, Mott R, Ciccarelli F, Copley RR, Ponting CP, Bork P. Recent improvements to the SMART domain-based sequence annotation resource. Nucleic Acids Research. 30: 242-4. PMID 11752305 DOI: 10.1093/Nar/30.1.242  0.502
2001 Ponting CP, Mott R, Bork P, Copley RR. Novel protein domains and repeats in Drosophila melanogaster: insights into structure, function, and evolution. Genome Research. 11: 1996-2008. PMID 11731489 DOI: 10.1101/Gr.198701  0.561
2001 Brockington M, Blake DJ, Prandini P, Brown SC, Torelli S, Benson MA, Ponting CP, Estournet B, Romero NB, Mercuri E, Voit T, Sewry CA, Guicheney P, Muntoni F. Mutations in the fukutin-related protein gene (FKRP) cause a form of congenital muscular dystrophy with secondary laminin deficiency and abnormal glycosylation of α-dystroglycan American Journal of Human Genetics. 69: 1198-1209. PMID 11592034 DOI: 10.1086/324412  0.329
2001 Lupas AN, Ponting CP, Russell RB. On the evolution of protein folds: are similar motifs in different protein folds the result of convergence, insertion, or relics of an ancient peptide world? Journal of Structural Biology. 134: 191-203. PMID 11551179 DOI: 10.1006/Jsbi.2001.4393  0.347
2001 Andrade MA, Perez-Iratxeta C, Ponting CP. Protein repeats: structures, functions, and evolution. Journal of Structural Biology. 134: 117-31. PMID 11551174 DOI: 10.1006/Jsbi.2001.4392  0.349
2001 Copley RR, Russell RB, Ponting CP. Sialidase-like Asp-boxes: sequence-similar structures within different protein folds. Protein Science : a Publication of the Protein Society. 10: 285-92. PMID 11266614 DOI: 10.1110/Ps.31901  0.372
2001 Lander ES, Linton LM, Birren B, Nusbaum C, Zody MC, Baldwin J, Devon K, Dewar K, Doyle M, FitzHugh W, Funke R, Gage D, Harris K, Heaford A, Howland J, ... ... Ponting CP, et al. Initial sequencing and analysis of the human genome. Nature. 409: 860-921. PMID 11237011 DOI: 10.1038/35057062  0.527
2001 Lander ES, Linton LM, Birren B, Nusbaum C, Zody MC, Baldwin J, Devon K, Dewar K, Doyle M, Fitzhugh W, Funke R, Gage D, Harris K, Heaford A, Howland J, ... ... Ponting CP, et al. Erratum: Initial sequencing and analysis of the human genome: International Human Genome Sequencing Consortium (Nature (2001) 409 (860-921)) Nature. 412: 565-566. DOI: 10.1038/35087627  0.527
2000 Ponting CP, Russell RB. Identification of distant homologues of fibroblast growth factors suggests a common ancestor for all beta-trefoil proteins. Journal of Molecular Biology. 302: 1041-7. PMID 11183773 DOI: 10.1006/Jmbi.2000.4087  0.32
2000 Newey SE, Benson MA, Ponting CP, Davies KE, Blake DJ. Alternative splicing of dystrobrevin regulates the stoichiometry of syntrophin binding to the dystrophin protein complex. Current Biology : Cb. 10: 1295-8. PMID 11069112 DOI: 10.1016/S0960-9822(00)00760-0  0.31
2000 Schultz J, Doerks T, Ponting CP, Copley RR, Bork P. More than 1,000 putative new human signalling proteins revealed by EST data mining. Nature Genetics. 25: 201-4. PMID 10835637 DOI: 10.1038/76069  0.552
2000 Ponting CP, Schultz J, Copley RR, Andrade MA, Bork P. Evolution of domain families. Advances in Protein Chemistry. 54: 185-244. PMID 10829229 DOI: 10.1016/S0065-3233(00)54007-8  0.448
2000 Andrade MA, Ponting CP, Gibson TJ, Bork P. Homology-based method for identification of protein repeats using statistical significance estimates. Journal of Molecular Biology. 298: 521-37. PMID 10772867 DOI: 10.1006/Jmbi.2000.3684  0.477
2000 Schultz J, Copley RR, Doerks T, Ponting CP, Bork P. SMART: a web-based tool for the study of genetically mobile domains. Nucleic Acids Research. 28: 231-4. PMID 10592234 DOI: 10.1093/Nar/28.1.231  0.487
1999 Copley RR, Ponting CP, Bork P. Phospholipases A2 and Wnts are unlikely to share a common ancestor. Current Biology : Cb. 9: R718-9. PMID 10712041 DOI: 10.1016/S0960-9822(99)80466-7  0.4
1999 Barnes MR, Russell RB, Copley RR, Ponting CP, Bork P, Cumberledge S, Reichsman F, Moore HM. A lipid-binding domain in Wnt: a case of mistaken identity? Current Biology : Cb. 9: R717-9. PMID 10531014 DOI: 10.1016/S0960-9822(99)80465-5  0.482
1999 Ponting CP, Hofmann K, Bork P. A latrophilin/CL-1-like GPS domain in polycystin-1. Current Biology : Cb. 9: R585-8. PMID 10469603 DOI: 10.1016/S0960-9822(99)80379-0  0.428
1999 Mohaghegh P, Rodrigues NR, Owen N, Ponting CP, Le TT, Burghes AH, Davies KE. Analysis of mutations in the tudor domain of the survival motor neuron protein SMN. European Journal of Human Genetics : Ejhg. 7: 519-25. PMID 10439956 DOI: 10.1038/Sj.Ejhg.5200346  0.317
1999 Ponting CP, Aravind L, Schultz J, Bork P, Koonin EV. Eukaryotic signalling domain homologues in archaea and bacteria. Ancient ancestry and horizontal gene transfer. Journal of Molecular Biology. 289: 729-45. PMID 10369758 DOI: 10.1006/Jmbi.1999.2827  0.5
1999 Copley RR, Schultz J, Ponting CP, Bork P. Protein families in multicellular organisms. Current Opinion in Structural Biology. 9: 408-15. PMID 10361098 DOI: 10.1016/S0959-440X(99)80055-4  0.544
1999 Ponting CP, Bork P, Schultz J, Aravind L. No Sec7-homology domain in guanine-nucleotide-exchange factors that act on Ras and Rho. Trends in Biochemical Sciences. 24: 177-8. PMID 10322430 DOI: 10.1016/S0968-0004(99)01379-1  0.438
1999 Ponting CP, Schultz J, Milpetz F, Bork P. SMART: identification and annotation of domains from signalling and extracellular protein sequences. Nucleic Acids Research. 27: 229-32. PMID 9847187 DOI: 10.1093/Nar/27.1.229  0.514
1998 Talbot K, Miguel-Aliaga I, Mohaghegh P, Ponting CP, Davies KE. Characterization of a gene encoding survival motor neuron (SMN)-related protein, a constituent of the spliceosome complex. Human Molecular Genetics. 7: 2149-56. PMID 9817934 DOI: 10.1093/Hmg/7.13.2149  0.351
1998 Russell RB, Ponting CP. Protein fold irregularities that hinder sequence analysis. Current Opinion in Structural Biology. 8: 364-71. PMID 9666333 DOI: 10.1016/S0959-440X(98)80071-7  0.326
1998 Kharrat A, Millevoi S, Baraldi E, Ponting CP, Bork P, Pastore A. Conformational stability studies of the pleckstrin DEP domain: definition of the domain boundaries. Biochimica Et Biophysica Acta. 1385: 157-64. PMID 9630596 DOI: 10.1016/S0167-4838(98)00041-7  0.482
1998 Schultz J, Milpetz F, Bork P, Ponting CP. SMART, a simple modular architecture research tool: identification of signaling domains. Proceedings of the National Academy of Sciences of the United States of America. 95: 5857-64. PMID 9600884 DOI: 10.1073/Pnas.95.11.5857  0.506
1997 Bork P, Schultz J, Ponting CP. Cytoplasmic signalling domains: the next generation. Trends in Biochemical Sciences. 22: 296-8. PMID 9270302 DOI: 10.1016/S0968-0004(97)01084-0  0.459
1997 Ponting CP, Cai YD, Bork P. The breast cancer gene product TSG101: a regulator of ubiquitination? Journal of Molecular Medicine (Berlin, Germany). 75: 467-9. PMID 9253709  0.436
1997 Ponting CP, Phillips C, Davies KE, Blake DJ. PDZ domains: targeting signalling molecules to sub-membranous sites. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 19: 469-79. PMID 9204764 DOI: 10.1002/Bies.950190606  0.307
1997 Ponting C, Schultz J, Bork P. SPRY domains in ryanodine receptors (Ca(2+)-release channels). Trends in Biochemical Sciences. 22: 193-4. PMID 9204703 DOI: 10.1016/S0968-0004(97)01049-9  0.409
1997 Talbot K, Ponting CP, Theodosiou AM, Rodrigues NR, Surtees R, Mountford R, Davies KE. Missense mutation clustering in the survival motor neuron gene: a role for a conserved tyrosine and glycine rich region of the protein in RNA metabolism? Human Molecular Genetics. 6: 497-500. PMID 9147655 DOI: 10.1093/Hmg/6.3.497  0.324
1997 Schultz J, Ponting CP, Hofmann K, Bork P. SAM as a protein interaction domain involved in developmental regulation. Protein Science : a Publication of the Protein Society. 6: 249-53. PMID 9007998 DOI: 10.1002/Pro.5560060128  0.5
1996 Haynie DT, Ponting CP. The N-terminal domains of tensin and auxilin are phosphatase homologues Protein Science. 5: 2643-2646. PMID 8976573 DOI: 10.1002/Pro.5560051227  0.333
1996 Ponting CP, Blake DJ, Davies KE, Kendrick-Jones J, Winder SJ. ZZ and TAZ: new putative zinc fingers in dystrophin and other proteins. Trends in Biochemical Sciences. 21: 11-13. PMID 8848831 DOI: 10.1016/S0968-0004(06)80020-4  0.334
1996 Ponting CP, Parker PJ. Extending the C2 domain family: C2s in PKCs δ, ε, η, θ, phospholipases, GAPs, and perforin Protein Science. 5: 162-166. PMID 8771209 DOI: 10.1002/Pro.5560050120  0.3
1996 Ponting CP, Bork P. Pleckstrin's repeat performance: a novel domain in G-protein signaling? Trends in Biochemical Sciences. 21: 245-6. PMID 8755244 DOI: 10.1016/S0968-0004(96)30027-3  0.453
1996 Doherty AJ, Serpell LC, Ponting CP. The helix-hairpin-helix DNA-binding motif: a structural basis for non-sequence-specific recognition of DNA. Nucleic Acids Research. 24: 2488-97. PMID 8692686 DOI: 10.1093/Nar/24.13.2488  0.309
1995 Ponting CP, Russell RB. Swaposins: circular permutations within genes encoding saposin homologues. Trends in Biochemical Sciences. 20: 179-80. PMID 7610480 DOI: 10.1016/S0968-0004(00)89003-9  0.328
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