Alex Gutteridge - Publications

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22 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Cao L, McDonnell A, Nitzsche A, Alexandrou A, Saintot PP, Loucif AJ, Brown AR, Young G, Mis M, Randall A, Waxman SG, Stanley P, Kirby S, Tarabar S, Gutteridge A, et al. Pharmacological reversal of a pain phenotype in iPSC-derived sensory neurons and patients with inherited erythromelalgia. Science Translational Medicine. 8: 335ra56. PMID 27099175 DOI: 10.1126/scitranslmed.aad7653  1
2016 Alexandrou AJ, Brown AR, Chapman ML, Estacion M, Turner J, Mis MA, Wilbrey A, Payne EC, Gutteridge A, Cox PJ, Doyle R, Printzenhoff D, Lin Z, Marron BE, West C, et al. Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release. Plos One. 11: e0152405. PMID 27050761 DOI: 10.1371/journal.pone.0152405  1
2015 Tassoni A, Gutteridge A, Barber AC, Osborne A, Martin KR. Molecular Mechanisms Mediating Retinal Reactive Gliosis Following Bone Marrow Mesenchymal Stem Cell Transplantation. Stem Cells (Dayton, Ohio). 33: 3006-16. PMID 26175331 DOI: 10.1002/stem.2095  1
2015 Choudhary P, Dodsworth BT, Sidders B, Gutteridge A, Michaelides C, Duckworth JK, Whiting PJ, Benn CL. A FOXM1 Dependent Mesenchymal-Epithelial Transition in Retinal Pigment Epithelium Cells. Plos One. 10: e0130379. PMID 26121260 DOI: 10.1371/journal.pone.0130379  1
2015 Berger ML, Lipset C, Gutteridge A, Axelsen K, Subedi P, Madigan D. Optimizing the leveraging of real-world data to improve the development and use of medicines. Value in Health : the Journal of the International Society For Pharmacoeconomics and Outcomes Research. 18: 127-30. PMID 25595243 DOI: 10.1016/j.jval.2014.10.009  1
2014 Young GT, Gutteridge A, Fox HD, Wilbrey AL, Cao L, Cho LT, Brown AR, Benn CL, Kammonen LR, Friedman JH, Bictash M, Whiting P, Bilsland JG, Stevens EB. Characterizing human stem cell-derived sensory neurons at the single-cell level reveals their ion channel expression and utility in pain research. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1530-43. PMID 24832007 DOI: 10.1038/mt.2014.86  1
2014 Sidders B, Brockel C, Gutteridge A, Harland L, Jansen PG, McEwen R, Michalovich D, Seidel H, Weiss B, Williams-Jones B, Woodwark M. Precompetitive activity to address the biological data needs of drug discovery. Nature Reviews. Drug Discovery. 13: 83-4. PMID 24481293 DOI: 10.1038/nrd4230  1
2013 Zarringhalam K, Enayetallah A, Gutteridge A, Sidders B, Ziemek D. Molecular causes of transcriptional response: a Bayesian prior knowledge approach. Bioinformatics (Oxford, England). 29: 3167-73. PMID 24078682 DOI: 10.1093/bioinformatics/btt557  1
2013 Gutteridge A, Rukstalis JM, Ziemek D, Tié M, Ji L, Ramos-Zayas R, Nardone NA, Norquay LD, Brenner MB, Tang K, McNeish JD, Rowntree RK. Novel pancreatic endocrine maturation pathways identified by genomic profiling and causal reasoning. Plos One. 8: e56024. PMID 23418498 DOI: 10.1371/journal.pone.0056024  1
2012 Surmacz B, Fox H, Gutteridge A, Fish P, Lubitz S, Whiting P. Directing differentiation of human embryonic stem cells toward anterior neural ectoderm using small molecules. Stem Cells (Dayton, Ohio). 30: 1875-84. PMID 22761025 DOI: 10.1002/stem.1166  1
2012 Pir P, Gutteridge A, Wu J, Rash B, Kell DB, Zhang N, Oliver SG. The genetic control of growth rate: a systems biology study in yeast. Bmc Systems Biology. 6: 4. PMID 22244311 DOI: 10.1186/1752-0509-6-4  1
2011 Bilsland E, Pir P, Gutteridge A, Johns A, King RD, Oliver SG. Functional expression of parasite drug targets and their human orthologs in yeast. Plos Neglected Tropical Diseases. 5: e1320. PMID 21991399 DOI: 10.1371/journal.pntd.0001320  1
2010 Katayama T, Arakawa K, Nakao M, Ono K, Aoki-Kinoshita KF, Yamamoto Y, Yamaguchi A, Kawashima S, Chun HW, Aerts J, Aranda B, Barboza LH, Bonnal RJ, Bruskiewich R, Bryne JC, ... ... Gutteridge A, et al. The DBCLS BioHackathon: standardization and interoperability for bioinformatics web services and workflows. The DBCLS BioHackathon Consortium*. Journal of Biomedical Semantics. 1: 8. PMID 20727200 DOI: 10.1186/2041-1480-1-8  1
2010 Gutteridge A, Pir P, Castrillo JI, Charles PD, Lilley KS, Oliver SG. Nutrient control of eukaryote cell growth: a systems biology study in yeast. Bmc Biology. 8: 68. PMID 20497545 DOI: 10.1186/1741-7007-8-68  1
2008 Yamanishi Y, Araki M, Gutteridge A, Honda W, Kanehisa M. Prediction of drug-target interaction networks from the integration of chemical and genomic spaces. Bioinformatics (Oxford, England). 24: i232-40. PMID 18586719 DOI: 10.1093/bioinformatics/btn162  1
2007 Gutteridge A, Kanehisa M, Goto S. Regulation of metabolic networks by small molecule metabolites. Bmc Bioinformatics. 8: 88. PMID 17352833 DOI: 10.1186/1471-2105-8-88  1
2006 Huang J, Gutteridge A, Honda W, Kanehisa M. MIMOX: a web tool for phage display based epitope mapping. Bmc Bioinformatics. 7: 451. PMID 17038191 DOI: 10.1186/1471-2105-7-451  1
2005 Gutteridge A, Thornton JM. Understanding nature's catalytic toolkit. Trends in Biochemical Sciences. 30: 622-9. PMID 16214343 DOI: 10.1016/j.tibs.2005.09.006  1
2005 George RA, Spriggs RV, Bartlett GJ, Gutteridge A, MacArthur MW, Porter CT, Al-Lazikani B, Thornton JM, Swindells MB. Effective function annotation through catalytic residue conservation. Proceedings of the National Academy of Sciences of the United States of America. 102: 12299-304. PMID 16037208 DOI: 10.1073/pnas.0504833102  1
2005 Gutteridge A, Thornton J. Conformational changes observed in enzyme crystal structures upon substrate binding. Journal of Molecular Biology. 346: 21-8. PMID 15663924 DOI: 10.1016/j.jmb.2004.11.013  1
2004 Gutteridge A, Thornton J. Conformational change in substrate binding, catalysis and product release: an open and shut case? Febs Letters. 567: 67-73. PMID 15165895 DOI: 10.1016/j.febslet.2004.03.067  1
2003 Gutteridge A, Bartlett GJ, Thornton JM. Using a neural network and spatial clustering to predict the location of active sites in enzymes. Journal of Molecular Biology. 330: 719-34. PMID 12850142  1
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