Year |
Citation |
Score |
2016 |
Cao L, McDonnell A, Nitzsche A, Alexandrou A, Saintot PP, Loucif AJ, Brown AR, Young G, Mis M, Randall A, Waxman SG, Stanley P, Kirby S, Tarabar S, Gutteridge A, et al. Pharmacological reversal of a pain phenotype in iPSC-derived sensory neurons and patients with inherited erythromelalgia. Science Translational Medicine. 8: 335ra56. PMID 27099175 DOI: 10.1126/scitranslmed.aad7653 |
1 |
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2016 |
Alexandrou AJ, Brown AR, Chapman ML, Estacion M, Turner J, Mis MA, Wilbrey A, Payne EC, Gutteridge A, Cox PJ, Doyle R, Printzenhoff D, Lin Z, Marron BE, West C, et al. Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release. Plos One. 11: e0152405. PMID 27050761 DOI: 10.1371/journal.pone.0152405 |
1 |
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2015 |
Tassoni A, Gutteridge A, Barber AC, Osborne A, Martin KR. Molecular Mechanisms Mediating Retinal Reactive Gliosis Following Bone Marrow Mesenchymal Stem Cell Transplantation. Stem Cells (Dayton, Ohio). 33: 3006-16. PMID 26175331 DOI: 10.1002/stem.2095 |
1 |
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2015 |
Choudhary P, Dodsworth BT, Sidders B, Gutteridge A, Michaelides C, Duckworth JK, Whiting PJ, Benn CL. A FOXM1 Dependent Mesenchymal-Epithelial Transition in Retinal Pigment Epithelium Cells. Plos One. 10: e0130379. PMID 26121260 DOI: 10.1371/journal.pone.0130379 |
1 |
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2015 |
Berger ML, Lipset C, Gutteridge A, Axelsen K, Subedi P, Madigan D. Optimizing the leveraging of real-world data to improve the development and use of medicines. Value in Health : the Journal of the International Society For Pharmacoeconomics and Outcomes Research. 18: 127-30. PMID 25595243 DOI: 10.1016/j.jval.2014.10.009 |
1 |
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2014 |
Young GT, Gutteridge A, Fox HD, Wilbrey AL, Cao L, Cho LT, Brown AR, Benn CL, Kammonen LR, Friedman JH, Bictash M, Whiting P, Bilsland JG, Stevens EB. Characterizing human stem cell-derived sensory neurons at the single-cell level reveals their ion channel expression and utility in pain research. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1530-43. PMID 24832007 DOI: 10.1038/mt.2014.86 |
1 |
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2014 |
Sidders B, Brockel C, Gutteridge A, Harland L, Jansen PG, McEwen R, Michalovich D, Seidel H, Weiss B, Williams-Jones B, Woodwark M. Precompetitive activity to address the biological data needs of drug discovery. Nature Reviews. Drug Discovery. 13: 83-4. PMID 24481293 DOI: 10.1038/nrd4230 |
1 |
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2013 |
Zarringhalam K, Enayetallah A, Gutteridge A, Sidders B, Ziemek D. Molecular causes of transcriptional response: a Bayesian prior knowledge approach. Bioinformatics (Oxford, England). 29: 3167-73. PMID 24078682 DOI: 10.1093/bioinformatics/btt557 |
1 |
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2013 |
Gutteridge A, Rukstalis JM, Ziemek D, Tié M, Ji L, Ramos-Zayas R, Nardone NA, Norquay LD, Brenner MB, Tang K, McNeish JD, Rowntree RK. Novel pancreatic endocrine maturation pathways identified by genomic profiling and causal reasoning. Plos One. 8: e56024. PMID 23418498 DOI: 10.1371/journal.pone.0056024 |
1 |
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2012 |
Surmacz B, Fox H, Gutteridge A, Fish P, Lubitz S, Whiting P. Directing differentiation of human embryonic stem cells toward anterior neural ectoderm using small molecules. Stem Cells (Dayton, Ohio). 30: 1875-84. PMID 22761025 DOI: 10.1002/stem.1166 |
1 |
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2012 |
Pir P, Gutteridge A, Wu J, Rash B, Kell DB, Zhang N, Oliver SG. The genetic control of growth rate: a systems biology study in yeast. Bmc Systems Biology. 6: 4. PMID 22244311 DOI: 10.1186/1752-0509-6-4 |
1 |
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2011 |
Bilsland E, Pir P, Gutteridge A, Johns A, King RD, Oliver SG. Functional expression of parasite drug targets and their human orthologs in yeast. Plos Neglected Tropical Diseases. 5: e1320. PMID 21991399 DOI: 10.1371/journal.pntd.0001320 |
1 |
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2010 |
Katayama T, Arakawa K, Nakao M, Ono K, Aoki-Kinoshita KF, Yamamoto Y, Yamaguchi A, Kawashima S, Chun HW, Aerts J, Aranda B, Barboza LH, Bonnal RJ, Bruskiewich R, Bryne JC, ... ... Gutteridge A, et al. The DBCLS BioHackathon: standardization and interoperability for bioinformatics web services and workflows. The DBCLS BioHackathon Consortium*. Journal of Biomedical Semantics. 1: 8. PMID 20727200 DOI: 10.1186/2041-1480-1-8 |
1 |
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2010 |
Gutteridge A, Pir P, Castrillo JI, Charles PD, Lilley KS, Oliver SG. Nutrient control of eukaryote cell growth: a systems biology study in yeast. Bmc Biology. 8: 68. PMID 20497545 DOI: 10.1186/1741-7007-8-68 |
1 |
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2008 |
Yamanishi Y, Araki M, Gutteridge A, Honda W, Kanehisa M. Prediction of drug-target interaction networks from the integration of chemical and genomic spaces. Bioinformatics (Oxford, England). 24: i232-40. PMID 18586719 DOI: 10.1093/bioinformatics/btn162 |
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2007 |
Gutteridge A, Kanehisa M, Goto S. Regulation of metabolic networks by small molecule metabolites. Bmc Bioinformatics. 8: 88. PMID 17352833 DOI: 10.1186/1471-2105-8-88 |
1 |
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2006 |
Huang J, Gutteridge A, Honda W, Kanehisa M. MIMOX: a web tool for phage display based epitope mapping. Bmc Bioinformatics. 7: 451. PMID 17038191 DOI: 10.1186/1471-2105-7-451 |
1 |
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2005 |
Gutteridge A, Thornton JM. Understanding nature's catalytic toolkit. Trends in Biochemical Sciences. 30: 622-9. PMID 16214343 DOI: 10.1016/j.tibs.2005.09.006 |
1 |
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2005 |
George RA, Spriggs RV, Bartlett GJ, Gutteridge A, MacArthur MW, Porter CT, Al-Lazikani B, Thornton JM, Swindells MB. Effective function annotation through catalytic residue conservation. Proceedings of the National Academy of Sciences of the United States of America. 102: 12299-304. PMID 16037208 DOI: 10.1073/pnas.0504833102 |
1 |
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2005 |
Gutteridge A, Thornton J. Conformational changes observed in enzyme crystal structures upon substrate binding. Journal of Molecular Biology. 346: 21-8. PMID 15663924 DOI: 10.1016/j.jmb.2004.11.013 |
1 |
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2004 |
Gutteridge A, Thornton J. Conformational change in substrate binding, catalysis and product release: an open and shut case? Febs Letters. 567: 67-73. PMID 15165895 DOI: 10.1016/j.febslet.2004.03.067 |
1 |
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2003 |
Gutteridge A, Bartlett GJ, Thornton JM. Using a neural network and spatial clustering to predict the location of active sites in enzymes. Journal of Molecular Biology. 330: 719-34. PMID 12850142 |
1 |
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