Nicolas Le Novère - Publications

1992-1999 Institut Pasteur, Paris, Paris, France 
 1999-2001 University of Cambridge, Cambridge, England, United Kingdom 
 2001-2003 Institut Pasteur, Paris, Paris, France 
 2003-2012 EMBL-European Bioinformatics Institute 
 2012- Babraham Institute, Babraham, England, United Kingdom 

128 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Pir P, Le Novère N. Mathematical models of pluripotent stem cells: At the dawn of predictive regenerative medicine Methods in Molecular Biology. 1386: 331-350. DOI: 10.1007/978-1-4939-3283-2_15  1
2015 Stanford NJ, Wolstencroft K, Golebiewski M, Kania R, Juty N, Tomlinson C, Owen S, Butcher S, Hermjakob H, Le Novère N, Mueller W, Snoep J, Goble C. The evolution of standards and data management practices in systems biology. Molecular Systems Biology. 11: 851. PMID 26700851 DOI: 10.15252/Msb.20156053  1
2015 Seeliger C, Le Novère N. Enabling surface dependent diffusion in spatial simulations using Smoldyn. Bmc Research Notes. 8: 752. PMID 26647064 DOI: 10.1186/S13104-015-1723-6  1
2015 Quinn JY, Cox RS, Adler A, Beal J, Bhatia S, Cai Y, Chen J, Clancy K, Galdzicki M, Hillson NJ, Le Novère N, Maheshwari AJ, McLaughlin JA, Myers CJ, P U, et al. SBOL Visual: A Graphical Language for Genetic Designs. Plos Biology. 13: e1002310. PMID 26633141 DOI: 10.1371/Journal.Pbio.1002310  1
2015 Hucka M, Bergmann FT, Dräger A, Hoops S, Keating SM, Le Novère N, Myers CJ, Olivier BG, Sahle S, Schaff JC, Smith LP, Waltemath D, Wilkinson DJ. Systems Biology Markup Language (SBML) Level 2 Version 5: Structures and Facilities for Model Definitions. Journal of Integrative Bioinformatics. 12: 271. PMID 26528569 DOI: 10.2390/Biecoll-Jib-2015-271  0.64
2015 Bergmann FT, Cooper J, Le Novère N, Nickerson D, Waltemath D. Simulation Experiment Description Markup Language (SED-ML) Level 1 Version 2. Journal of Integrative Bioinformatics. 12: 262. PMID 26528560 DOI: 10.2390/biecoll-jib-2015-262  1
2015 Bergmann FT, Rodriguez N, Le Novère N. COMBINE Archive Specification Version 1. Journal of Integrative Bioinformatics. 12: 261. PMID 26528559 DOI: 10.2390/biecoll-jib-2015-261  1
2015 Schreiber F, Bader GD, Golebiewski M, Hucka M, Kormeier B, Le Novère N, Myers C, Nickerson D, Sommer B, Waltemath D, Weise S. Specifications of Standards in Systems and Synthetic Biology. Journal of Integrative Bioinformatics. 12: 258. PMID 26528556 DOI: 10.2390/Biecoll-Jib-2015-258  1
2015 Ebrahim A, Almaas E, Bauer E, Bordbar A, Burgard AP, Chang RL, Dräger A, Famili I, Feist AM, Fleming RM, Fong SS, Hatzimanikatis V, Herrgård MJ, Holder A, Hucka M, et al. Do genome-scale models need exact solvers or clearer standards? Molecular Systems Biology. 11: 831. PMID 26467284 DOI: 10.15252/Msb.20156157  0.64
2015 Swat MJ, Moodie S, Wimalaratne SM, Kristensen NR, Lavielle M, Mari A, Magni P, Smith MK, Bizzotto R, Pasotti L, Mezzalana E, Comets E, Sarr C, Terranova N, Blaudez E, et al. Pharmacometrics Markup Language (PharmML): Opening New Perspectives for Model Exchange in Drug Development. Cpt: Pharmacometrics & Systems Pharmacology. 4: 316-9. PMID 26225259 DOI: 10.1002/psp4.57  1
2015 Juty N, Ali R, Glont M, Keating S, Rodriguez N, Swat MJ, Wimalaratne SM, Hermjakob H, Le Novère N, Laibe C, Chelliah V. BioModels: Content, Features, Functionality, and Use. Cpt: Pharmacometrics & Systems Pharmacology. 4: e3. PMID 26225232 DOI: 10.1002/psp4.3  1
2015 Rodriguez N, Thomas A, Watanabe L, Vazirabad IY, Kofia V, Gómez HF, Mittag F, Matthes J, Rudolph J, Wrzodek F, Netz E, Diamantikos A, Eichner J, Keller R, Wrzodek C, et al. JSBML 1.0: providing a smorgasbord of options to encode systems biology models. Bioinformatics (Oxford, England). PMID 26079347 DOI: 10.1093/Bioinformatics/Btv341  1
2015 Hucka M, Nickerson DP, Bader GD, Bergmann FT, Cooper J, Demir E, Garny A, Golebiewski M, Myers CJ, Schreiber F, Waltemath D, Le Novère N. Promoting Coordinated Development of Community-Based Information Standards for Modeling in Biology: The COMBINE Initiative. Frontiers in Bioengineering and Biotechnology. 3: 19. PMID 25759811 DOI: 10.3389/Fbioe.2015.00019  0.8
2015 Wimalaratne SM, Bolleman J, Juty N, Katayama T, Dumontier M, Redaschi N, Le Novère N, Hermjakob H, Laibe C. SPARQL-enabled identifier conversion with Bioinformatics (Oxford, England). 31: 1875-7. PMID 25638809 DOI: 10.1093/Bioinformatics/Btv064  0.44
2015 Dutta-Roy R, Rosenmund C, Edelstein SJ, Le Novère N. Ligand-dependent opening of the multiple AMPA receptor conductance states: a concerted model. Plos One. 10: e0116616. PMID 25629405 DOI: 10.1371/Journal.Pone.0116616  1
2015 Naldi A, Monteiro PT, Müssel C, Kestler HA, Thieffry D, Xenarios I, Saez-Rodriguez J, Helikar T, Chaouiya C. Cooperative development of logical modelling standards and tools with CoLoMoTo. Bioinformatics (Oxford, England). 31: 1154-9. PMID 25619997 DOI: 10.1093/Bioinformatics/Btv013  1
2015 Lai M, Brun D, Edelstein SJ, Le Novère N. Modulation of calmodulin lobes by different targets: an allosteric model with hemiconcerted conformational transitions. Plos Computational Biology. 11: e1004063. PMID 25611683 DOI: 10.1371/Journal.Pcbi.1004063  1
2015 Deans AR, Lewis SE, Huala E, Anzaldo SS, Ashburner M, Balhoff JP, Blackburn DC, Blake JA, Burleigh JG, Chanet B, Cooper LD, Courtot M, Csösz S, Cui H, Dahdul W, et al. Finding our way through phenotypes. Plos Biology. 13: e1002033. PMID 25562316 DOI: 10.1371/Journal.Pbio.1002033  1
2015 Chelliah V, Juty N, Ajmera I, Ali R, Dumousseau M, Glont M, Hucka M, Jalowicki G, Keating S, Knight-Schrijver V, Lloret-Villas A, Natarajan KN, Pettit JB, Rodriguez N, Schubert M, et al. BioModels: ten-year anniversary. Nucleic Acids Research. 43: D542-8. PMID 25414348 DOI: 10.1093/Nar/Gku1181  1
2014 Bergmann FT, Adams R, Moodie S, Cooper J, Glont M, Golebiewski M, Hucka M, Laibe C, Miller AK, Nickerson DP, Olivier BG, Rodriguez N, Sauro HM, Scharm M, Soiland-Reyes S, et al. COMBINE archive and OMEX format: one file to share all information to reproduce a modeling project. Bmc Bioinformatics. 15: 369. PMID 25494900 DOI: 10.1186/S12859-014-0369-Z  1
2014 Wimalaratne SM, Grenon P, Hermjakob H, Le Novère N, Laibe C. BioModels linked dataset. Bmc Systems Biology. 8: 91. PMID 25182954 DOI: 10.1186/S12918-014-0091-5  1
2014 Jupp S, Malone J, Bolleman J, Brandizi M, Davies M, Garcia L, Gaulton A, Gehant S, Laibe C, Redaschi N, Wimalaratne SM, Martin M, Le Novère N, Parkinson H, Birney E, et al. The EBI RDF platform: linked open data for the life sciences. Bioinformatics (Oxford, England). 30: 1338-9. PMID 24413672 DOI: 10.1093/Bioinformatics/Btt765  1
2013 Chaouiya C, Bérenguier D, Keating SM, Naldi A, van Iersel MP, Rodriguez N, Dräger A, Büchel F, Cokelaer T, Kowal B, Wicks B, Gonçalves E, Dorier J, Page M, Monteiro PT, et al. SBML qualitative models: a model representation format and infrastructure to foster interactions between qualitative modelling formalisms and tools. Bmc Systems Biology. 7: 135. PMID 24321545 DOI: 10.1186/1752-0509-7-135  1
2013 Büchel F, Rodriguez N, Swainston N, Wrzodek C, Czauderna T, Keller R, Mittag F, Schubert M, Glont M, Golebiewski M, van Iersel M, Keating S, Rall M, Wybrow M, Hermjakob H, et al. Path2Models: large-scale generation of computational models from biochemical pathway maps. Bmc Systems Biology. 7: 116. PMID 24180668 DOI: 10.1186/1752-0509-7-116  1
2013 Mattioni M, Le Novère N. Integration of biochemical and electrical signaling-multiscale model of the medium spiny neuron of the striatum. Plos One. 8: e66811. PMID 23843966 DOI: 10.1371/Journal.Pone.0066811  1
2013 Stefan MI, Le Novère N. Cooperative binding. Plos Computational Biology. 9: e1003106. PMID 23843752 DOI: 10.1371/journal.pcbi.1003106  1
2013 Ajmera I, Swat M, Laibe C, Le Novère N, Chelliah V. The impact of mathematical modeling on the understanding of diabetes and related complications. Cpt: Pharmacometrics & Systems Pharmacology. 2: e54. PMID 23842097 DOI: 10.1038/psp.2013.30  0.36
2013 Keller R, Dörr A, Tabira A, Funahashi A, Ziller MJ, Adams R, Rodriguez N, Le Novère N, Hiroi N, Planatscher H, Zell A, Dräger A. The systems biology simulation core algorithm. Bmc Systems Biology. 7: 55. PMID 23826941 DOI: 10.1186/1752-0509-7-55  0.4
2013 Juty N, Laibe C, Le Novère N. Controlled annotations for systems biology. Methods in Molecular Biology (Clifton, N.J.). 1021: 227-45. PMID 23715988 DOI: 10.1007/978-1-62703-450-0_12  0.36
2013 Keating SM, Le Novère N. Supporting SBML as a model exchange format in software applications. Methods in Molecular Biology (Clifton, N.J.). 1021: 201-25. PMID 23715987 DOI: 10.1007/978-1-62703-450-0_11  1
2013 Chelliah V, Laibe C, Le Novère N. BioModels Database: a repository of mathematical models of biological processes. Methods in Molecular Biology (Clifton, N.J.). 1021: 189-99. PMID 23715986 DOI: 10.1007/978-1-62703-450-0_10  1
2013 Le Novère N, Endler L. Using chemical kinetics to model biochemical pathways. Methods in Molecular Biology (Clifton, N.J.). 1021: 147-67. PMID 23715984 DOI: 10.1007/978-1-62703-450-0_8  1
2013 Juty N, Le Novère N, Hermjakob H, Laibe C. Towards the collaborative curation of the registry underlying Database : the Journal of Biological Databases and Curation. 2013: bat017. PMID 23584831 DOI: 10.1093/Database/Bat017  1
2013 Edelstein SJ, Le Novère N. Cooperativity of allosteric receptors. Journal of Molecular Biology. 425: 1424-32. PMID 23523898 DOI: 10.1016/J.Jmb.2013.03.011  1
2013 Thiele I, Swainston N, Fleming RM, Hoppe A, Sahoo S, Aurich MK, Haraldsdottir H, Mo ML, Rolfsson O, Stobbe MD, Thorleifsson SG, Agren R, Bölling C, Bordel S, Chavali AK, et al. A community-driven global reconstruction of human metabolism. Nature Biotechnology. 31: 419-25. PMID 23455439 DOI: 10.1038/Nbt.2488  1
2013 von Eichborn J, Dunkel M, Gohlke BO, Preissner SC, Hoffmann MF, Bauer JM, Armstrong JD, Schaefer MH, Andrade-Navarro MA, Le Novere N, Croning MD, Grant SG, van Nierop P, Smit AB, Preissner R. SynSysNet: integration of experimental data on synaptic protein-protein interactions with drug-target relations. Nucleic Acids Research. 41: D834-40. PMID 23143269 DOI: 10.1093/nar/gks1040  1
2012 Zhukova A, Adams R, Laibe C, Le Novère N. LibKiSAO: a Java library for Querying KiSAO. Bmc Research Notes. 5: 520. PMID 23006857 DOI: 10.1186/1756-0500-5-520  1
2012 Li L, Stefan MI, Le Novère N. Calcium input frequency, duration and amplitude differentially modulate the relative activation of calcineurin and CaMKII. Plos One. 7: e43810. PMID 22962589 DOI: 10.1371/Journal.Pone.0043810  1
2012 Büchel F, Wrzodek C, Mittag F, Dräger A, Eichner J, Rodriguez N, Le Novère N, Zell A. Qualitative translation of relations from BioPAX to SBML qual. Bioinformatics (Oxford, England). 28: 2648-53. PMID 22923304 DOI: 10.1093/bioinformatics/bts508  1
2012 Adams RR, Tsorman N, Stratford K, Akman OE, Gilmore S, Juty N, Le Novère N, Millar AJ, Millar AJ. The Input Signal Step Function (ISSF), a standard method to encode input signals in SBML models with software support, applied to circadian clock models. Journal of Biological Rhythms. 27: 328-32. PMID 22855577 DOI: 10.1177/0748730412451077  1
2012 Mattioni M, Cohen U, Le Novère N. Neuronvisio: A Graphical User Interface with 3D Capabilities for NEURON. Frontiers in Neuroinformatics. 6: 20. PMID 22685429 DOI: 10.3389/Fninf.2012.00020  1
2012 Dumousseau M, Rodriguez N, Juty N, Le Novère N. MELTING, a flexible platform to predict the melting temperatures of nucleic acids. Bmc Bioinformatics. 13: 101. PMID 22591039 DOI: 10.1186/1471-2105-13-101  0.36
2012 van Iersel MP, Villéger AC, Czauderna T, Boyd SE, Bergmann FT, Luna A, Demir E, Sorokin A, Dogrusoz U, Matsuoka Y, Funahashi A, Aladjem MI, Mi H, Moodie SL, Kitano H, et al. Software support for SBGN maps: SBGN-ML and LibSBGN. Bioinformatics (Oxford, England). 28: 2016-21. PMID 22581176 DOI: 10.1093/Bioinformatics/Bts270  1
2012 Stefan MI, Marshall DP, Le Novère N. Structural analysis and stochastic modelling suggest a mechanism for calmodulin trapping by CaMKII. Plos One. 7: e29406. PMID 22279535 DOI: 10.1371/Journal.Pone.0029406  1
2012 Juty N, Le Novère N, Laibe C. and MIRIAM Registry: community resources to provide persistent identification. Nucleic Acids Research. 40: D580-6. PMID 22140103 DOI: 10.1093/nar/gkr1097  0.36
2012 Demir E, Cary MP, Paley S, Fukuda K, Lemer C, Vastrik I, Wu G, D'Eustachio P, Schaefer C, Luciano J, Schacherer F, Martinez-Flores I, Hu Z, Jimenez-Jacinto V, Joshi-Tope G, et al. The BioPAX community standard for pathway data sharing (Nature Biotechnology (2010) 28, (935-942)) Nature Biotechnology. 30: 365. DOI: 10.1038/Nbt0412-365C  1
2012 Keating SM, Le Novère N. Encoding neuronal models in SBML Computational Systems Neurobiology. 459-488. DOI: 10.1007/978-94-007-3858-4_15  1
2012 Hastings J, Le Novère N, Ceusters W, Mulligan K, Smith B. Wanting what we don't want to want: Representing addiction in interoperable bio-ontologies Ceur Workshop Proceedings. 897.  1
2012 Juty N, Le Novère N, Hermjakob H, Laibe C. Delivering "Cool URIs" that do not change Ceur Workshop Proceedings. 952.  1
2011 Le Novère N, Hucka M, Anwar N, Bader GD, Demir E, Moodie S, Sorokin A. Meeting report from the first meetings of the Computational Modeling in Biology Network (COMBINE). Standards in Genomic Sciences. 5: 230-42. PMID 22180826 DOI: 10.4056/Sigs.5279417  1
2011 Waltemath D, Adams R, Bergmann FT, Hucka M, Kolpakov F, Miller AK, Moraru II, Nickerson D, Sahle S, Snoep JL, Le Novère N. Reproducible computational biology experiments with SED-ML--the Simulation Experiment Description Markup Language. Bmc Systems Biology. 5: 198. PMID 22172142 DOI: 10.1186/1752-0509-5-198  1
2011 Courtot M, Juty N, Knüpfer C, Waltemath D, Zhukova A, Dräger A, Dumontier M, Finney A, Golebiewski M, Hastings J, Hoops S, Keating S, Kell DB, Kerrien S, Lawson J, et al. Controlled vocabularies and semantics in systems biology. Molecular Systems Biology. 7: 543. PMID 22027554 DOI: 10.1038/Msb.2011.77  1
2011 Schulz M, Krause F, Le Novère N, Klipp E, Liebermeister W. Retrieval, alignment, and clustering of computational models based on semantic annotations. Molecular Systems Biology. 7: 512. PMID 21772260 DOI: 10.1038/msb.2011.41  1
2011 Dräger A, Rodriguez N, Dumousseau M, Dörr A, Wrzodek C, Le Novère N, Zell A, Hucka M. JSBML: a flexible Java library for working with SBML. Bioinformatics (Oxford, England). 27: 2167-8. PMID 21697129 DOI: 10.1093/Bioinformatics/Btr361  1
2011 Waltemath D, Adams R, Beard DA, Bergmann FT, Bhalla US, Britten R, Chelliah V, Cooling MT, Cooper J, Crampin EJ, Garny A, Hoops S, Hucka M, Hunter P, Klipp E, et al. Minimum Information About a Simulation Experiment (MIASE). Plos Computational Biology. 7: e1001122. PMID 21552546 DOI: 10.1371/Journal.Pcbi.1001122  1
2010 Hucka M, Le Novère N. Software that goes with the flow in systems biology. Bmc Biology. 8: 140. PMID 21114874 DOI: 10.1186/1741-7007-8-140  1
2010 Demir E, Cary MP, Paley S, Fukuda K, Lemer C, Vastrik I, Wu G, D'Eustachio P, Schaefer C, Luciano J, Schacherer F, Martinez-Flores I, Hu Z, Jimenez-Jacinto V, Joshi-Tope G, et al. The BioPAX community standard for pathway data sharing. Nature Biotechnology. 28: 935-42. PMID 20829833 DOI: 10.1038/Nbt.1666  0.8
2010 Henkel R, Endler L, Peters A, Le Novère N, Waltemath D. Ranked retrieval of Computational Biology models. Bmc Bioinformatics. 11: 423. PMID 20701772 DOI: 10.1186/1471-2105-11-423  1
2010 Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C. BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. Bmc Systems Biology. 4: 92. PMID 20587024 DOI: 10.1186/1752-0509-4-92  1
2010 Baldi BF, Hoyer C, Le Novère N. Schizophrenic: forever young? Genome Medicine. 2: 32. PMID 20497602 DOI: 10.1186/Gm153  1
2010 Tolle DP, Le Novère N. Brownian diffusion of AMPA receptors is sufficient to explain fast onset of LTP. Bmc Systems Biology. 4: 25. PMID 20233407 DOI: 10.1186/1752-0509-4-25  1
2010 Tolle DP, Le Novère N. Meredys, a multi-compartment reaction-diffusion simulator using multistate realistic molecular complexes. Bmc Systems Biology. 4: 24. PMID 20233406 DOI: 10.1186/1752-0509-4-24  1
2010 Edelstein SJ, Stefan MI, Le Novère N. Ligand depletion in vivo modulates the dynamic range and cooperativity of signal transduction. Plos One. 5: e8449. PMID 20052284 DOI: 10.1371/Journal.Pone.0008449  1
2010 Li C, Courtot M, Le Novère N, Laibe C. Web Services, a free and integrated toolkit for computational modelling software. Briefings in Bioinformatics. 11: 270-7. PMID 19939940 DOI: 10.1093/bib/bbp056  1
2009 Le Novère N, Hucka M, Mi H, Moodie S, Schreiber F, Sorokin A, Demir E, Wegner K, Aladjem MI, Wimalaratne SM, Bergman FT, Gauges R, Ghazal P, Kawaji H, Li L, et al. The Systems Biology Graphical Notation. Nature Biotechnology. 27: 735-41. PMID 19668183 DOI: 10.1038/Nbt.1558  0.8
2009 Stefan MI, Edelstein SJ, Le Novère N. Computing phenomenologic Adair-Klotz constants from microscopic MWC parameters. Bmc Systems Biology. 3: 68. PMID 19602261 DOI: 10.1186/1752-0509-3-68  1
2009 Wolkenhauer O, Fell D, De Meyts P, Blüthgen N, Herzel H, Le Novère N, Höfer T, Schürrle K, van Leeuwen I. SysBioMed report: advancing systems biology for medical applications. Iet Systems Biology. 3: 131-6. PMID 19449974 DOI: 10.1049/Iet-Syb.2009.0005  1
2009 Endler L, Rodriguez N, Juty N, Chelliah V, Laibe C, Li C, Le Novère N. Designing and encoding models for synthetic biology. Journal of the Royal Society, Interface / the Royal Society. 6: S405-17. PMID 19364720 DOI: 10.1098/rsif.2009.0035.focus  1
2009 Chelliah V, Endler L, Juty N, Laibe C, Li C, Rodriguez N, Le Novère N. Data integration and semantic enrichment of systems biology models and simulations Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 5647: 5-15. DOI: 10.1007/978-3-642-02879-3_2  1
2008 HerrgÃ¥rd MJ, Swainston N, Dobson P, Dunn WB, Arga KY, Arvas M, Blüthgen N, Borger S, Costenoble R, Heinemann M, Hucka M, Le Novère N, Li P, Liebermeister W, Mo ML, et al. A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology. Nature Biotechnology. 26: 1155-60. PMID 18846089 DOI: 10.1038/Nbt1492  1
2008 Le Novère N. Neurological disease: are systems approaches the way forward? Pharmacopsychiatry. 41: S28-31. PMID 18756417 DOI: 10.1055/s-2008-1080913  1
2008 Guerlet G, Taly A, Prado de Carvalho L, Martz A, Jiang R, Specht A, Le Novère N, Grutter T. Comparative models of P2X2 receptor support inter-subunit ATP-binding sites. Biochemical and Biophysical Research Communications. 375: 405-9. PMID 18718445 DOI: 10.1016/J.Bbrc.2008.08.030  0.52
2008 Stefan MI, Edelstein SJ, Le Novère N. An allosteric model of calmodulin explains differential activation of PP2B and CaMKII. Proceedings of the National Academy of Sciences of the United States of America. 105: 10768-73. PMID 18669651 DOI: 10.1073/Pnas.0804672105  1
2008 Le Novère N, Li L, Girault JA. DARPP-32: molecular integration of phosphorylation potential. Cellular and Molecular Life Sciences : Cmls. 65: 2125-7. PMID 18488140 DOI: 10.1007/S00018-008-8150-Y  1
2008 Shimizu TS, Le Novère N. Looking inside the box: bacterial transistor arrays. Molecular Microbiology. 69: 5-9. PMID 18484950 DOI: 10.1111/j.1365-2958.2008.06240.x  1
2008 Stefan MI, Edelstein SJ, Le Novère N. An allosteric model of calmodulin explains differential activation of PP2B and CaMKII (Proceedings of the National Academy of Sciences of the United States of America (2008) 105, 31, (10768-10773) DOI: 10.1073/pnas.0804672105) Proceedings of the National Academy of Sciences of the United States of America. 105: 19024. DOI: 10.1073/pnas.0810309105  1
2008 Le Novère N. Multiscale modelling of neuronal signalling Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 5307: 7. DOI: 10.1007/978-3-540-88562-7_4  1
2008 Köhn D, Le Novère N. SED-ML - An XML format for the implementation of the MIASE guidelines Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 5307: 176-190. DOI: 10.1007/978-3-540-88562-7_15  1
2007 Laibe C, Le Novère N. MIRIAM Resources: tools to generate and resolve robust cross-references in Systems Biology. Bmc Systems Biology. 1: 58. PMID 18078503 DOI: 10.1186/1752-0509-1-58  1
2007 Le Novère N. The long journey to a Systems Biology of neuronal function. Bmc Systems Biology. 1: 28. PMID 17567903 DOI: 10.1186/1752-0509-1-28  1
2007 Rodriguez N, Donizelli M, Le Novère N. SBMLeditor: effective creation of models in the Systems Biology Markup language (SBML). Bmc Bioinformatics. 8: 79. PMID 17341299 DOI: 10.1186/1471-2105-8-79  1
2007 Shapiro BE, Finney A, Hucka M, Bornstein B, Funahashi A, Jouraku A, Keating SM, Le Novère N, Matthews J, Schilstra MJ. SBML models and MathSBML Introduction to Systems Biology. 395-421. DOI: 10.1007/978-1-59745-531-2_20  1
2006 Fernandez E, Schiappa R, Girault JA, Le Novère N. DARPP-32 is a robust integrator of dopamine and glutamate signals. Plos Computational Biology. 2: e176. PMID 17194217 DOI: 10.1371/journal.pcbi.0020176  1
2006 Le Novère N. Model storage, exchange and integration. Bmc Neuroscience. 7: S11. PMID 17118155 DOI: 10.1186/1471-2202-7-S1-S11  1
2006 Schilstra MJ, Li L, Matthews J, Finney A, Hucka M, Le Novère N. CellML2SBML: conversion of CellML into SBML. Bioinformatics (Oxford, England). 22: 1018-20. PMID 16473867 DOI: 10.1093/Bioinformatics/Btl047  1
2006 Le Novère N, Bornstein B, Broicher A, Courtot M, Donizelli M, Dharuri H, Li L, Sauro H, Schilstra M, Shapiro B, Snoep JL, Hucka M. BioModels Database: a free, centralized database of curated, published, quantitative kinetic models of biochemical and cellular systems. Nucleic Acids Research. 34: D689-91. PMID 16381960 DOI: 10.1093/Nar/Gkj092  1
2006 Donizelli M, Djite MA, Le Novère N. LGICdb: a manually curated sequence database after the genomes. Nucleic Acids Research. 34: D267-9. PMID 16381861 DOI: 10.1093/Nar/Gkj104  1
2005 Le Novère N, Finney A, Hucka M, Bhalla US, Campagne F, Collado-Vides J, Crampin EJ, Halstead M, Klipp E, Mendes P, Nielsen P, Sauro H, Shapiro B, Snoep JL, Spence HD, et al. Minimum information requested in the annotation of biochemical models (MIRIAM). Nature Biotechnology. 23: 1509-15. PMID 16333295 DOI: 10.1038/Nbt1156  1
2005 Taly A, Delarue M, Grutter T, Nilges M, Le Novère N, Corringer PJ, Changeux JP. Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism. Biophysical Journal. 88: 3954-65. PMID 15805177 DOI: 10.1529/Biophysj.104.050229  1
2004 Le Novère N, Donizelli M. The Molecular Pages of the mesotelencephalic dopamine consortium (DopaNet). Bmc Bioinformatics. 5: 174. PMID 15518589 DOI: 10.1186/1471-2105-5-174  1
2004 Grutter T, Le Novère N, Changeux JP. Rational understanding of nicotinic receptors drug binding. Current Topics in Medicinal Chemistry. 4: 645-50. PMID 14965300 DOI: 10.2174/1568026043451177  1
2004 Sallette J, Bohler S, Benoit P, Soudant M, Pons S, Le Novère N, Changeux JP, Corringer PJ. An extracellular protein microdomain controls up-regulation of neuronal nicotinic acetylcholine receptors by nicotine. The Journal of Biological Chemistry. 279: 18767-75. PMID 14764595 DOI: 10.1074/jbc.M308260200  1
2003 Champtiaux N, Gotti C, Cordero-Erausquin M, David DJ, Przybylski C, Léna C, Clementi F, Moretti M, Rossi FM, Le Novère N, McIntosh JM, Gardier AM, Changeux JP. Subunit composition of functional nicotinic receptors in dopaminergic neurons investigated with knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7820-9. PMID 12944511 DOI: 10.1523/Jneurosci.23-21-07820.2003  1
2003 Grutter T, Prado de Carvalho L, Le Novère N, Corringer PJ, Edelstein S, Changeux JP. An H-bond between two residues from different loops of the acetylcholine binding site contributes to the activation mechanism of nicotinic receptors. The Embo Journal. 22: 1990-2003. PMID 12727867 DOI: 10.1093/Emboj/Cdg197  1
2003 Han ZY, Zoli M, Cardona A, Bourgeois JP, Changeux JP, Le Novère N. Localization of [3H]nicotine, [3H]cytisine, [3H]epibatidine, and [125I]alpha-bungarotoxin binding sites in the brain of Macaca mulatta. The Journal of Comparative Neurology. 461: 49-60. PMID 12722104 DOI: 10.1002/cne.10659  1
2003 Hucka M, Finney A, Sauro HM, Bolouri H, Doyle JC, Kitano H, Arkin AP, Bornstein BJ, Bray D, Cornish-Bowden A, Cuellar AA, Dronov S, Gilles ED, Ginkel M, Gor V, et al. The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models. Bioinformatics (Oxford, England). 19: 524-31. PMID 12611808 DOI: 10.1093/Bioinformatics/Btg015  1
2003 Courtois V, Chatelain G, Han ZY, Le Novère N, Brun G, Lamonerie T. New Otx2 mRNA isoforms expressed in the mouse brain. Journal of Neurochemistry. 84: 840-53. PMID 12562527 DOI: 10.1046/j.1471-4159.2003.01583.x  1
2003 Le Novère N. Neuronal communication in post-genomic era: The DopaNet project | La communication neuronale à l'ère post-génomique: Le projet DopaNet Biofutur. 20-24.  1
2002 Le Novère N, Corringer PJ, Changeux JP. The diversity of subunit composition in nAChRs: evolutionary origins, physiologic and pharmacologic consequences. Journal of Neurobiology. 53: 447-56. PMID 12436412 DOI: 10.1002/neu.10153  1
2002 Ferrari R, Le Novère N, Picciotto MR, Changeux JP, Zoli M. Acute and long-term changes in the mesolimbic dopamine pathway after systemic or local single nicotine injections. The European Journal of Neuroscience. 15: 1810-8. PMID 12081661 DOI: 10.1046/j.1460-9568.2001.02009.x  1
2002 Fruchart-Gaillard C, Gilquin B, Antil-Delbeke S, Le Novère N, Tamiya T, Corringer PJ, Changeux JP, Ménez A, Servent D. Experimentally based model of a complex between a snake toxin and the alpha 7 nicotinic receptor. Proceedings of the National Academy of Sciences of the United States of America. 99: 3216-21. PMID 11867717 DOI: 10.1073/Pnas.042699899  1
2002 Le Novère N, Grutter T, Changeux JP. Models of the extracellular domain of the nicotinic receptors and of agonist- and Ca2+-binding sites. Proceedings of the National Academy of Sciences of the United States of America. 99: 3210-5. PMID 11867716 DOI: 10.1073/Pnas.042699699  1
2001 Le Novère N. MELTING, computing the melting temperature of nucleic acid duplex. Bioinformatics (Oxford, England). 17: 1226-7. PMID 11751232  1
2001 Le Novère N, Changeux JP. The Ligand Gated Ion Channel database: an example of a sequence database in neuroscience. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 356: 1121-30. PMID 11545694 DOI: 10.1098/rstb.2001.0903  1
2001 Le Novère N, Shimizu TS. STOCHSIM: modelling of stochastic biomolecular processes. Bioinformatics (Oxford, England). 17: 575-6. PMID 11395441  1
2001 Lacombe B, Becker D, Hedrich R, DeSalle R, Hollmann M, Kwak JM, Schroeder JI, Le Novère N, Nam HG, Spalding EP, Tester M, Turano FJ, Chiu J, Coruzzi G. The identity of plant glutamate receptors. Science (New York, N.Y.). 292: 1486-7. PMID 11379626 DOI: 10.1126/Science.292.5521.1486B  1
2001 Duke TA, Le Novère N, Bray D. Conformational spread in a ring of proteins: a stochastic approach to allostery. Journal of Molecular Biology. 308: 541-53. PMID 11327786 DOI: 10.1006/Jmbi.2001.4610  1
2001 Le Novère N, Changeux JP. LGICdb: the ligand-gated ion channel database. Nucleic Acids Research. 29: 294-5. PMID 11125117 DOI: 10.1093/Nar/29.1.294  1
2000 Shimizu TS, Le Novère N, Levin MD, Beavil AJ, Sutton BJ, Bray D. Molecular model of a lattice of signalling proteins involved in bacterial chemotaxis. Nature Cell Biology. 2: 792-6. PMID 11056533 DOI: 10.1038/35041030  1
2000 Han ZY, Le Novère N, Zoli M, Hill JA, Champtiaux N, Changeux JP. Localization of nAChR subunit mRNAs in the brain of Macaca mulatta. The European Journal of Neuroscience. 12: 3664-74. PMID 11029636 DOI: 10.1046/j.1460-9568.2000.00262.x  1
2000 Rogner UC, Spyropoulos DD, Le Novère N, Changeux JP, Avner P. Control of neurulation by the nucleosome assembly protein-1-like 2. Nature Genetics. 25: 431-5. PMID 10932189 DOI: 10.1038/78124  1
2000 Corringer PJ, Le Novère N, Changeux JP. Nicotinic receptors at the amino acid level. Annual Review of Pharmacology and Toxicology. 40: 431-58. PMID 10836143 DOI: 10.1146/annurev.pharmtox.40.1.431  0.92
1999 le Novère N, Zoli M, Léna C, Ferrari R, Picciotto MR, Merlo-Pich E, Changeux JP. Involvement of alpha6 nicotinic receptor subunit in nicotine-elicited locomotion, demonstrated by in vivo antisense oligonucleotide infusion. Neuroreport. 10: 2497-501. PMID 10574359  1
1999 Léna C, de Kerchove D'Exaerde A, Cordero-Erausquin M, Le Novère N, del Mar Arroyo-Jimenez M, Changeux JP. Diversity and distribution of nicotinic acetylcholine receptors in the locus ceruleus neurons. Proceedings of the National Academy of Sciences of the United States of America. 96: 12126-31. PMID 10518587 DOI: 10.1073/Pnas.96.21.12126  1
1999 Lukas RJ, Changeux JP, Le Novère N, Albuquerque EX, Balfour DJ, Berg DK, Bertrand D, Chiappinelli VA, Clarke PB, Collins AC, Dani JA, Grady SR, Kellar KJ, Lindstrom JM, Marks MJ, et al. International Union of Pharmacology. XX. Current status of the nomenclature for nicotinic acetylcholine receptors and their subunits. Pharmacological Reviews. 51: 397-401. PMID 10353988  1
1999 Marubio LM, del Mar Arroyo-Jimenez M, Cordero-Erausquin M, Léna C, Le Novère N, de Kerchove d'Exaerde A, Huchet M, Damaj MI, Changeux JP. Reduced antinociception in mice lacking neuronal nicotinic receptor subunits. Nature. 398: 805-10. PMID 10235262 DOI: 10.1038/19756  1
1999 Le Novère N, Corringer PJ, Changeux JP. Improved secondary structure predictions for a nicotinic receptor subunit: incorporation of solvent accessibility and experimental data into a two-dimensional representation. Biophysical Journal. 76: 2329-45. PMID 10233052 DOI: 10.1016/S0006-3495(99)77390-X  1
1999 Le Novère N, Changeux JP. The Ligand Gated Ion Channel Database. Nucleic Acids Research. 27: 340-2. PMID 9847222 DOI: 10.1093/nar/27.1.340  1
1998 Changeux JP, Bertrand D, Corringer PJ, Dehaene S, Edelstein S, Léna C, Le Novère N, Marubio L, Picciotto M, Zoli M. Brain nicotinic receptors: structure and regulation, role in learning and reinforcement. Brain Research. Brain Research Reviews. 26: 198-216. PMID 9651527 DOI: 10.1016/S0165-0173(97)00040-4  1
1998 Le Novère N. Approches théoriques et pratiques en hybridation in situ et autoradiographie réceptorielle Annales De L'Institut Pasteur/Actualites. 9: 259-270.  1
1997 Beeri R, Le Novère N, Mervis R, Huberman T, Grauer E, Changeux JP, Soreq H. Enhanced hemicholinium binding and attenuated dendrite branching in cognitively impaired acetylcholinesterase-transgenic mice. Journal of Neurochemistry. 69: 2441-51. PMID 9375677 DOI: 10.1046/J.1471-4159.1997.69062441.X  1
1996 Changeux JP, Bessis A, Bourgeois JP, Corringer PJ, Devillers-Thiery A, Eiselé JL, Kerszberg M, Léna C, Le Novère N, Picciotto M, Zoli M. Nicotinic receptors and brain plasticity. Cold Spring Harbor Symposia On Quantitative Biology. 61: 343-62. PMID 9246464  1
1996 Le Novère N, Zoli M, Changeux JP. Neuronal nicotinic receptor alpha 6 subunit mRNA is selectively concentrated in catecholaminergic nuclei of the rat brain. The European Journal of Neuroscience. 8: 2428-39. PMID 8950106  0.64
1995 Bessis A, Salmon AM, Zoli M, Le Novère N, Picciotto M, Changeux JP. Promoter elements conferring neuron-specific expression of the beta 2-subunit of the neuronal nicotinic acetylcholine receptor studied in vitro and in transgenic mice. Neuroscience. 69: 807-19. PMID 8596650 DOI: 10.1016/0306-4522(95)00303-Z  1
1995 Zoli M, Le Novère N, Hill JA, Changeux JP. Developmental regulation of nicotinic ACh receptor subunit mRNAs in the rat central and peripheral nervous systems. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 1912-39. PMID 7891142  0.56
1995 Picciotto MR, Zoli M, Léna C, Bessis A, Lallemand Y, Le Novère N, Vincent P, Pich EM, Brûlet P, Changeux JP. Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain. Nature. 374: 65-7. PMID 7870173 DOI: 10.1038/374065A0  0.6
1995 Le Novère N, Changeux JP. Molecular evolution of the nicotinic acetylcholine receptor: an example of multigene family in excitable cells. Journal of Molecular Evolution. 40: 155-72. PMID 7699721 DOI: 10.1007/Bf00167110  0.96
1995 Li XM, Zoli M, Finnman UB, Le Novère N, Changeux JP, Fuxe K. A single (-)-nicotine injection causes change with a time delay in the affinity of striatal D2 receptors for antagonist, but not for agonist, nor in the D2 receptor mRNA levels in the rat substantia nigra. Brain Research. 679: 157-67. PMID 7648259 DOI: 10.1016/0006-8993(95)00228-I  0.52
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