| Year |
Citation |
Score |
| 2021 |
Pagnon de la Vega M, Giedraitis V, Michno W, Kilander L, Güner G, Zielinski M, Löwenmark M, Brundin R, Danfors T, Söderberg L, Alafuzoff I, Nilsson LNG, Erlandsson A, Willbold D, Müller SA, et al. The deletion causes early onset autosomal dominant Alzheimer's disease by altering APP processing and increasing amyloid β fibril formation. Science Translational Medicine. 13. PMID 34380771 DOI: 10.1126/scitranslmed.abc6184 |
0.308 |
|
| 2021 |
Libard S, Walter J, Alafuzoff I. In vivo Characterization of Biochemical Variants of Amyloid-β in Subjects with Idiopathic Normal Pressure Hydrocephalus and Alzheimer's Disease Neuropathological Change. Journal of Alzheimer's Disease : Jad. 80: 1003-1012. PMID 33612546 DOI: 10.3233/JAD-201469 |
0.305 |
|
| 2019 |
Agnarsdóttir M, Popova S, Alafuzoff I. Expression of CMV protein pp65 in cutaneous malignant melanoma. Plos One. 14. PMID 31603931 DOI: 10.1371/Journal.Pone.0223854 |
0.301 |
|
| 2019 |
Luikku AJ, Hall A, Nerg O, Koivisto AM, Hiltunen M, Helisalmi S, Herukka SK, Junkkari A, Sutela A, Kojoukhova M, Korhonen V, Mattila J, Lötjönen J, Rummukainen J, Alafuzoff I, et al. Predicting Development of Alzheimer's Disease in Patients with Shunted Idiopathic Normal Pressure Hydrocephalus. Journal of Alzheimer's Disease : Jad. PMID 31498122 DOI: 10.3233/Jad-190334 |
0.418 |
|
| 2019 |
Nelson PT, Dickson DW, Trojanowski JQ, Jack CR, Boyle PA, Arfanakis K, Rademakers R, Alafuzoff I, Attems J, Brayne C, Coyle-Gilchrist ITS, Chui HC, Fardo DW, Flanagan ME, Halliday G, et al. Erratum: Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report. (Brain (2019) 142, (1503–1527) DOI: 10.1093/brain/awz099) Brain. 142. PMID 31147685 DOI: 10.1093/Brain/Awz163 |
0.307 |
|
| 2019 |
Libard S, Alafuzoff I. Alzheimer's disease neuropathological change and loss of matrix/neuropil in patients with idiopathic Normal Pressure Hydrocephalus, a model of Alzheimer's disease. Acta Neuropathologica Communications. 7: 98. PMID 31142354 DOI: 10.1186/S40478-019-0748-9 |
0.43 |
|
| 2019 |
Nelson PT, Dickson DW, Trojanowski JQ, Jack CR, Boyle PA, Arfanakis K, Rademakers R, Alafuzoff I, Attems J, Brayne C, Coyle-Gilchrist ITS, Chui HC, Fardo DW, Flanagan ME, Halliday G, et al. Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report. Brain : a Journal of Neurology. PMID 31039256 DOI: 10.1093/Brain/Awz099 |
0.425 |
|
| 2019 |
Rinne JO, Suotunen T, Rummukainen J, Herukka SK, Nerg O, Koivisto AM, Rauramaa T, Någren K, Hiltunen M, Alafuzoff I, Rinne J, Jääskeläinen JE, Soininen H, Leinonen V. [11C]PIB PET Is Associated with the Brain Biopsy Amyloid-β Load in Subjects Examined for Normal Pressure Hydrocephalus. Journal of Alzheimer's Disease. 67: 1343-1351. PMID 30689567 DOI: 10.3233/Jad-180645 |
0.404 |
|
| 2018 |
Rauramaa T, Saxlin A, Lohvansuu K, Alafuzoff I, Pitkänen A, Soininen H. Epilepsy in neuropathologically verified Alzheimer's disease. Seizure-European Journal of Epilepsy. 58: 9-12. PMID 29602145 DOI: 10.1016/J.Seizure.2018.03.014 |
0.376 |
|
| 2018 |
Alafuzoff I. Minimal neuropathologic diagnosis for brain banking in the normal middle-aged and aged brain and in neurodegenerative disorders Handbook of Clinical Neurology. 150: 131-141. PMID 29496136 DOI: 10.1016/B978-0-444-63639-3.00010-4 |
0.419 |
|
| 2018 |
Libard S, Laurell K, Cesarini KG, Alafuzoff I. Progression of Alzheimer's Disease-Related Pathology and Cell Counts in a Patient with Idiopathic Normal Pressure Hydrocephalus. Journal of Alzheimer's Disease. 61: 1451-1462. PMID 29376849 DOI: 10.3233/Jad-170446 |
0.455 |
|
| 2018 |
Pyykkö OT, Nerg O, Niskasaari H, Niskasaari T, Koivisto AM, Hiltunen M, Pihlajamäki J, Rauramaa T, Kojoukhova M, Alafuzoff I, Soininen H, Jääskeläinen JE, Leinonen V. Incidence, Comorbidities, and Mortality in Idiopathic Normal Pressure Hydrocephalus. World Neurosurgery. 112. PMID 29374607 DOI: 10.1016/J.Wneu.2018.01.107 |
0.327 |
|
| 2018 |
Ygland E, van Westen D, Englund E, Rademakers R, Wszolek ZK, Nilsson K, Nilsson C, Landqvist Waldö M, Alafuzoff I, Hansson O, Gustafson L, Puschmann A. Slowly progressive dementia caused by MAPT R406W mutations: longitudinal report on a new kindred and systematic review. Alzheimer's Research & Therapy. 10: 2. PMID 29370822 DOI: 10.1186/S13195-017-0330-2 |
0.343 |
|
| 2018 |
Abu Hamdeh S, Virhammar J, Sehlin D, Alafuzoff I, Cesarini KG, Marklund N. Brain tissue Aβ42 levels are linked to shunt response in idiopathic normal pressure hydrocephalus. Journal of Neurosurgery. 1-9. PMID 29350601 DOI: 10.3171/2017.7.Jns171005 |
0.399 |
|
| 2017 |
Alafuzoff I. Techniques in neuropathology. Handbook of Clinical Neurology. 145: 3-7. PMID 28987177 DOI: 10.1016/B978-0-12-802395-2.00001-8 |
0.34 |
|
| 2017 |
Velickaite V, Giedraitis V, Ström K, Alafuzoff I, Zetterberg H, Lannfelt L, Kilander L, Larsson E, Ingelsson M. Cognitive function in very old men does not correlate to biomarkers of Alzheimer’s disease Bmc Geriatrics. 17: 208-208. PMID 28886705 DOI: 10.1186/S12877-017-0601-6 |
0.414 |
|
| 2017 |
Roy A, Libard S, Weishaupt H, Gustavsson I, Uhrbom L, Hesselager G, Swartling FJ, Pontén F, Alafuzoff I, Tchougounova E. Mast Cell Infiltration in Human Brain Metastases Modulates the Microenvironment and Contributes to the Metastatic Potential. Frontiers in Oncology. 7: 115. PMID 28626727 DOI: 10.3389/Fonc.2017.00115 |
0.311 |
|
| 2017 |
Kovacs GG, Xie SX, Lee EB, Robinson JL, Caswell C, Irwin DJ, Toledo JB, Johnson VE, Smith DH, Alafuzoff I, Attems J, Bencze J, Bieniek KF, Bigio EH, Bodi I, et al. Multisite Assessment of Aging-Related Tau Astrogliopathy (ARTAG). Journal of Neuropathology and Experimental Neurology. PMID 28591867 DOI: 10.1093/Jnen/Nlx041 |
0.304 |
|
| 2017 |
Leino M, Popova SN, Alafuzoff I. Transactive DNA Binding Protein 43 Rather Than Other Misfolded Proteins in the Brain is Associated with Islet Amyloid Polypeptide in Pancreas in Aged Subjects with Diabetes Mellitus Journal of Alzheimer's Disease. 59: 43-56. PMID 28582864 DOI: 10.3233/Jad-170192 |
0.362 |
|
| 2017 |
Abu Hamdeh S, Waara ER, Möller C, Söderberg L, Basun H, Alafuzoff I, Hillered L, Lannfelt L, Ingelsson M, Marklund N. Rapid amyloid-β oligomer and protofibril accumulation in traumatic brain injury. Brain Pathology (Zurich, Switzerland). PMID 28557010 DOI: 10.1111/Bpa.12532 |
0.388 |
|
| 2017 |
Rauramaa T, Solomon A, Pikkarainen M, Kälviäinen R, Alafuzoff I. Hippocampal Sclerosis and Epilepsy in Elderly Population Journal of Alzheimers Disease & Parkinsonism. 7: 1-4. DOI: 10.4172/2161-0460.1000384 |
0.353 |
|
| 2016 |
Laiterä T, Paananen J, Helisalmi S, Sarajärvi T, Huovinen J, Laitinen M, Rauramaa T, Alafuzoff I, Remes AM, Soininen H, Haapasalo A, Jääskeläinen JE, Leinonen V, Hiltunen M. Effects of Alzheimer's Disease-Associated Risk Loci on Amyloid-β Accumulation in the Brain of Idiopathic Normal Pressure Hydrocephalus Patients Journal of Alzheimer's Disease. 55: 995-1003. PMID 27802227 DOI: 10.3233/Jad-160554 |
0.421 |
|
| 2016 |
Luikku AJ, Hall A, Nerg O, Koivisto AM, Hiltunen M, Helisalmi S, Herukka SK, Sutela A, Kojoukhova M, Mattila J, Lötjönen J, Rummukainen J, Alafuzoff I, Jääskeläinen JE, Remes AM, et al. Multimodal analysis to predict shunt surgery outcome of 284 patients with suspected idiopathic normal pressure hydrocephalus. Acta Neurochirurgica. PMID 27743250 DOI: 10.1007/S00701-016-2980-4 |
0.339 |
|
| 2016 |
Muñoz-Ruiz MÁ, Hall A, Mattila J, Koikkalainen J, Herukka SK, Husso M, Hänninen T, Vanninen R, Liu Y, Hallikainen M, Lötjönen J, Remes AM, Alafuzoff I, Soininen H, Hartikainen P. Using the Disease State Fingerprint Tool for Differential Diagnosis of Frontotemporal Dementia and Alzheimer's Disease. Dementia and Geriatric Cognitive Disorders Extra. 6: 313-329. PMID 27703465 DOI: 10.1159/000447122 |
0.34 |
|
| 2016 |
McAleese KE, Alafuzoff I, Charidimou A, De Reuck J, Grinberg LT, Hainsworth AH, Hortobagyi T, Ince P, Jellinger K, Gao J, Kalaria RN, Kovacs GG, Kövari E, Love S, Popovic M, et al. Post-mortem assessment in vascular dementia: advances and aspirations. Bmc Medicine. 14: 129. PMID 27600683 DOI: 10.1186/S12916-016-0676-5 |
0.352 |
|
| 2016 |
Sutovsky S, Smolek T, Alafuzoff I, Blaho A, Parrak V, Turcani P, Palkovic M, Petrovic R, Novak M, Zilka N. Atypical Huntington's disease with the clinical presentation of behavioural variant of frontotemporal dementia. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 27287334 DOI: 10.1007/S00702-016-1579-5 |
0.426 |
|
| 2016 |
Kok EH, Karppinen TT, Luoto T, Alafuzoff I, Karhunen PJ. Beer Drinking Associates with Lower Burden of Amyloid Beta Aggregation in the Brain: Helsinki Sudden Death Series. Alcoholism, Clinical and Experimental Research. PMID 27218874 DOI: 10.1111/Acer.13102 |
0.368 |
|
| 2016 |
Flygt J, Gumucio A, Ingelsson M, Skoglund K, Holm J, Alafuzoff I, Marklund N. Human Traumatic Brain Injury Results in Oligodendrocyte Death and Increases the Number of Oligodendrocyte Progenitor Cells. Journal of Neuropathology and Experimental Neurology. PMID 27105664 DOI: 10.1093/Jnen/Nlw025 |
0.317 |
|
| 2016 |
Koivisto AM, Kurki MI, Alafuzoff I, Sutela A, Rummukainen J, Savolainen S, Vanninen R, Jääskeläinen JE, Soininen H, Leinonen V. High Risk of Dementia in Ventricular Enlargement with Normal Pressure Hydrocephalus Related Symptoms1. Journal of Alzheimer's Disease. 52: 497-507. PMID 27031474 DOI: 10.3233/Jad-150909 |
0.351 |
|
| 2016 |
Elobeid A, Libard S, Leino M, Popova SN, Alafuzoff I. Altered Proteins in the Aging Brain. Journal of Neuropathology and Experimental Neurology. 75: 316-325. PMID 26979082 DOI: 10.1093/Jnen/Nlw002 |
0.373 |
|
| 2016 |
Alafuzoff I, Popova SN, Wanders A, Veress B. Neuronal Protein Alteration in Enteric Dysmotility Syndrome Journal of Alzheimer’S Disease & Parkinsonism. 6: 1-4. DOI: 10.4172/2161-0460.1000212 |
0.308 |
|
| 2015 |
Kovacs GG, Ferrer I, Grinberg LT, Alafuzoff I, Attems J, Budka H, Cairns NJ, Crary JF, Duyckaerts C, Ghetti B, Halliday GM, Ironside JW, Love S, Mackenzie IR, Munoz DG, et al. Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy. Acta Neuropathologica. PMID 26659578 DOI: 10.1007/S00401-015-1509-X |
0.393 |
|
| 2015 |
Popova SN, Pesälä S, Alafuzoff I. To Stage Alzheimer’s Disease Related Neurodegeneration Using one Section of Hippocampus Journal of Alzheimer's Disease. 48: 597-601. PMID 26402117 DOI: 10.3233/Jad-150494 |
0.385 |
|
| 2015 |
Elobeid A, Laurell K, Cesarini KG, Alafuzoff I. Correlations between mini-mental state examination score, cerebrospinal fluid biomarkers, and pathology observed in brain biopsies of patients with normal-pressure hydrocephalus. Journal of Neuropathology and Experimental Neurology. 74: 470-9. PMID 25868149 DOI: 10.1097/Nen.0000000000000191 |
0.428 |
|
| 2015 |
Jellinger KA, Alafuzoff I, Attems J, Beach TG, Cairns NJ, Crary JF, Dickson DW, Hof PR, Hyman BT, Jack CR, Jicha GA, Knopman DS, Kovacs GG, Mackenzie IR, Masliah E, et al. PART, a distinct tauopathy, different from classical sporadic Alzheimer disease. Acta Neuropathologica. 129: 757-62. PMID 25778618 DOI: 10.1007/S00401-015-1407-2 |
0.431 |
|
| 2015 |
Herukka SK, Rummukainen J, Ihalainen J, von Und Zu Fraunberg M, Koivisto AM, Nerg O, Puli LK, Seppälä TT, Zetterberg H, Pyykkö OT, Helisalmi S, Tanila H, Alafuzoff I, Hiltunen M, Rinne J, et al. Amyloid-β and Tau Dynamics in Human Brain Interstitial Fluid in Patients with Suspected Normal Pressure Hydrocephalus. Journal of Alzheimer's Disease : Jad. PMID 25720406 DOI: 10.3233/Jad-142862 |
0.423 |
|
| 2015 |
Alafuzoff I, Pikkarainen M, Neumann M, Arzberger T, Al-Sarraj S, Bodi I, Bogdanovic N, Bugiani O, Ferrer I, Gelpi E, Gentleman S, Giaccone G, Graeber MB, Hortobagyi T, Ince PG, et al. Erratum to: Neuropathological assessments of the pathology in frontotemporal lobar degeneration with TDP43-positive inclusions: an inter-laboratory study by the BrainNet Europe consortium. Journal of Neural Transmission (Vienna, Austria : 1996). 122: 973-4. PMID 25418279 DOI: 10.1007/S00702-014-1337-5 |
0.322 |
|
| 2015 |
Martiskainen H, Viswanathan J, Nykänen NP, Kurki M, Helisalmi S, Natunen T, Sarajärvi T, Kurkinen KM, Pursiheimo JP, Rauramaa T, Alafuzoff I, Jääskeläinen JE, Leinonen V, Soininen H, Haapasalo A, et al. Transcriptomics and mechanistic elucidation of Alzheimer's disease risk genes in the brain and in vitro models. Neurobiology of Aging. 36: 1221.e15-28. PMID 25281018 DOI: 10.1016/J.Neurobiolaging.2014.09.003 |
0.425 |
|
| 2015 |
Laiterä T, Kurki MI, Pursiheimo JP, Zetterberg H, Helisalmi S, Rauramaa T, Alafuzoff I, Remes AM, Soininen H, Haapasalo A, Jääskeläinen JE, Hiltunen M, Leinonen V. The expression of transthyretin and amyloid-β protein precursor is altered in the brain of idiopathic normal pressure hydrocephalus patients Journal of Alzheimer's Disease. 48: 959-968. DOI: 10.3233/Jad-150268 |
0.34 |
|
| 2014 |
Crary JF, Trojanowski JQ, Schneider JA, Abisambra JF, Abner EL, Alafuzoff I, Arnold SE, Attems J, Beach TG, Bigio EH, Cairns NJ, Dickson DW, Gearing M, Grinberg LT, Hof PR, et al. Primary age-related tauopathy (PART): a common pathology associated with human aging. Acta Neuropathologica. 128: 755-66. PMID 25348064 DOI: 10.1007/S00401-014-1349-0 |
0.451 |
|
| 2014 |
Libard S, Popova SN, Amini RM, Kärjä V, Pietiläinen T, Hämäläinen KM, Sundström C, Hesselager G, Bergqvist M, Ekman S, Zetterling M, Smits A, Nilsson P, Pfeifer S, de Ståhl TD, ... ... Alafuzoff I, et al. Human cytomegalovirus tegument protein pp65 is detected in all intra- and extra-axial brain tumours independent of the tumour type or grade. Plos One. 9: e108861. PMID 25268364 DOI: 10.1371/Journal.Pone.0108861 |
0.334 |
|
| 2014 |
Sutinen EM, Korolainen MA, Häyrinen J, Alafuzoff I, Petratos S, Salminen A, Soininen H, Pirttilä T, Ojala JO. Interleukin-18 alters protein expressions of neurodegenerative diseases-linked proteins in human SH-SY5Y neuron-like cells. Frontiers in Cellular Neuroscience. 8: 214. PMID 25147500 DOI: 10.3389/Fncel.2014.00214 |
0.361 |
|
| 2014 |
Elobeid A, Rantakömi S, Soininen H, Alafuzoff I. Alzheimer's disease-related plaques in nondemented subjects. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 522-9. PMID 24742915 DOI: 10.1016/J.Jalz.2012.12.009 |
0.36 |
|
| 2014 |
Laiterä T, Sarajärvi T, Haapasalo A, Puli L, Kauppinen T, Mäkinen P, Rauramaa T, Tanila H, Jääskeläinen JE, Alafuzoff I, Soininen H, Leinonen V, Hiltunen M. Increased γ-secretase activity in idiopathic normal pressure hydrocephalus patients with β-amyloid pathology. Plos One. 9: e93717. PMID 24699723 DOI: 10.1371/Journal.Pone.0093717 |
0.421 |
|
| 2014 |
Pyykkö OT, Lumela M, Rummukainen J, Nerg O, Seppälä TT, Herukka SK, Koivisto AM, Alafuzoff I, Puli L, Savolainen S, Soininen H, Jääskeläinen JE, Hiltunen M, Zetterberg H, Leinonen V. Cerebrospinal fluid biomarker and brain biopsy findings in idiopathic normal pressure hydrocephalus. Plos One. 9: e91974. PMID 24638077 DOI: 10.1371/Journal.Pone.0091974 |
0.44 |
|
| 2014 |
Gallagher MD, Suh E, Grossman M, Elman L, McCluskey L, Van Swieten JC, Al-Sarraj S, Neumann M, Gelpi E, Ghetti B, Rohrer JD, Halliday G, Van Broeckhoven C, Seilhean D, Shaw PJ, ... ... Alafuzoff I, et al. TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions. Acta Neuropathologica. 127: 407-18. PMID 24442578 DOI: 10.1007/S00401-013-1239-X |
0.309 |
|
| 2014 |
Alafuzoff I, Parkkinen L. Staged pathology in Parkinson's disease. Parkinsonism & Related Disorders. 20: S57-61. PMID 24262190 DOI: 10.1016/S1353-8020(13)70016-6 |
0.335 |
|
| 2014 |
Laiterä T, Sarajärvi T, Haapasalo A, Puli LK, Kauppinen T, Mäkinen P, Rauramaa T, Tanila H, Jääskeläinen JE, Alafuzoff I, Soininen H, Leinonen V, Hiltunen M. Increased Gamma-Secretase Activity In Idiopathic Normal Pressure Hydrocephalus Patients With B-Amyloid Pathology Alzheimers & Dementia. 10. DOI: 10.1016/J.Jalz.2014.05.318 |
0.309 |
|
| 2013 |
Natunen T, Martiskainen H, Sarajärvi T, Helisalmi S, Pursiheimo JP, Viswanathan J, Laitinen M, Mäkinen P, Kauppinen T, Rauramaa T, Leinonen V, Alafuzoff I, Haapasalo A, Soininen H, Hiltunen M. Effects of NR1H3 genetic variation on the expression of liver X receptor α and the progression of Alzheimer's disease. Plos One. 8: e80700. PMID 24278306 DOI: 10.1371/Journal.Pone.0080700 |
0.385 |
|
| 2013 |
Natunen T, Parrado AR, Helisalmi S, Pursiheimo JP, Sarajärvi T, Mäkinen P, Kurkinen KM, Mullin K, Alafuzoff I, Haapasalo A, Bertram L, Soininen H, Tanzi RE, Hiltunen M. Elucidation of the BACE1 regulating factor GGA3 in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 37: 217-32. PMID 23970038 DOI: 10.3233/Jad-130104 |
0.421 |
|
| 2013 |
Popova SN, Alafuzoff I. Distribution of SLC10A4, a synaptic vesicle protein in the human brain, and the association of this protein with Alzheimer's disease-related neuronal degeneration. Journal of Alzheimer's Disease : Jad. 37: 603-10. PMID 23948907 DOI: 10.3233/Jad-130548 |
0.392 |
|
| 2013 |
Rauramaa T, Pikkarainen M, Englund E, Ince PG, Jellinger K, Paetau A, Alafuzoff I. Consensus recommendations on pathologic changes in the hippocampus: a postmortem multicenter inter-rater study. Journal of Neuropathology and Experimental Neurology. 72: 452-61. PMID 23656988 DOI: 10.1097/Nen.0B013E318292492A |
0.334 |
|
| 2013 |
Kämäläinen A, Viswanathan J, Natunen T, Helisalmi S, Kauppinen T, Pikkarainen M, Pursiheimo JP, Alafuzoff I, Kivipelto M, Haapasalo A, Soininen H, Herukka SK, Hiltunen M. GRN variant rs5848 reduces plasma and brain levels of granulin in Alzheimer's disease patients. Journal of Alzheimer's Disease : Jad. 33: 23-7. PMID 22890097 DOI: 10.3233/Jad-2012-120946 |
0.363 |
|
| 2013 |
Alafuzoff I. Alzheimer's disease-related lesions. Journal of Alzheimer's Disease : Jad. 33: S173-9. PMID 22695621 DOI: 10.3233/Jad-2012-129024 |
0.366 |
|
| 2013 |
Kovacs GG, Rozemuller AJ, van Swieten JC, Gelpi E, Majtenyi K, Al-Sarraj S, Troakes C, Bódi I, King A, Hortobágyi T, Esiri MM, Ansorge O, Giaccone G, Ferrer I, Arzberger T, ... ... Alafuzoff I, et al. Neuropathology of the hippocampus in FTLD-Tau with Pick bodies: a study of the BrainNet Europe Consortium. Neuropathology and Applied Neurobiology. 39: 166-78. PMID 22471883 DOI: 10.1111/J.1365-2990.2012.01272.X |
0.397 |
|
| 2013 |
Leinonen V, Alafuzoff I, Savolainen S, Sutela A, Rummukainen J, Kurki M, Soininen H, Rinne J, Jääskeläinen JE, Koivisto A. Significant risk of dementia in shunt-responsive idiopathic normal pressure hydrocephalus Alzheimers & Dementia. 9: 748. DOI: 10.1016/J.Jalz.2013.05.1511 |
0.317 |
|
| 2012 |
Pyykkö OT, Helisalmi S, Koivisto AM, Mölsä JA, Rummukainen J, Nerg O, Alafuzoff I, Savolainen S, Soininen H, Jääskeläinen JE, Rinne J, Leinonen V, Hiltunen M. APOE4 predicts amyloid-β in cortical brain biopsy but not idiopathic normal pressure hydrocephalus. Journal of Neurology, Neurosurgery, and Psychiatry. 83: 1119-24. PMID 22955176 DOI: 10.1136/Jnnp-2011-303849 |
0.421 |
|
| 2012 |
Alafuzoff I, Gelpi E, Al-Sarraj S, Arzberger T, Attems J, Bodi I, Bogdanovic N, Budka H, Bugiani O, Englund E, Ferrer I, Gentleman S, Giaccone G, Graeber MB, Hortobagyi T, et al. The need to unify neuropathological assessments of vascular alterations in the ageing brain: multicentre survey by the BrainNet Europe consortium. Experimental Gerontology. 47: 825-33. PMID 22705312 DOI: 10.1016/J.Exger.2012.06.001 |
0.349 |
|
| 2012 |
Seppälä TT, Nerg O, Koivisto AM, Rummukainen J, Puli L, Zetterberg H, Pyykkö OT, Helisalmi S, Alafuzoff I, Hiltunen M, Jääskeläinen JE, Rinne J, Soininen H, Leinonen V, Herukka SK. CSF biomarkers for Alzheimer disease correlate with cortical brain biopsy findings. Neurology. 78: 1568-75. PMID 22517093 DOI: 10.1212/Wnl.0B013E3182563Bd0 |
0.439 |
|
| 2012 |
Nelson PT, Alafuzoff I, Bigio EH, Bouras C, Braak H, Cairns NJ, Castellani RJ, Crain BJ, Davies P, Del Tredici K, Duyckaerts C, Frosch MP, Haroutunian V, Hof PR, Hulette CM, et al. Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature. Journal of Neuropathology and Experimental Neurology. 71: 362-81. PMID 22487856 DOI: 10.1097/Nen.0B013E31825018F7 |
0.408 |
|
| 2012 |
Kovacs GG, Wagner U, Dumont B, Pikkarainen M, Osman AA, Streichenberger N, Leisser I, Verchère J, Baron T, Alafuzoff I, Budka H, Perret-Liaudet A, Lachmann I. An antibody with high reactivity for disease-associated α-synuclein reveals extensive brain pathology. Acta Neuropathologica. 124: 37-50. PMID 22370907 DOI: 10.1007/S00401-012-0964-X |
0.323 |
|
| 2012 |
Leinonen V, Koivisto AM, Alafuzoff I, Pyykkö OT, Rummukainen J, von Und Zu Fraunberg M, Jääskeläinen JE, Soininen H, Rinne J, Savolainen S. Cortical brain biopsy in long-term prognostication of 468 patients with possible normal pressure hydrocephalus. Neuro-Degenerative Diseases. 10: 166-9. PMID 22343771 DOI: 10.1159/000335155 |
0.43 |
|
| 2012 |
Popova SN, Tarvainen I, Capellari S, Parchi P, Hannikainen P, Pirinen E, Haapasalo H, Alafuzoff I. Divergent clinical and neuropathological phenotype in a Gerstmann-Sträussler-Scheinker P102L family. Acta Neurologica Scandinavica. 126: 315-23. PMID 22211828 DOI: 10.1111/J.1600-0404.2011.01628.X |
0.35 |
|
| 2012 |
Elobeid A, Soininen H, Alafuzoff I. Hyperphosphorylated tau in young and middle-aged subjects. Acta Neuropathologica. 123: 97-104. PMID 22160320 DOI: 10.1007/S00401-011-0906-Z |
0.387 |
|
| 2012 |
Salminen A, Kaarniranta K, Haapasalo A, Hiltunen M, Soininen H, Alafuzoff I. Emerging role of p62/sequestosome-1 in the pathogenesis of Alzheimer's disease. Progress in Neurobiology. 96: 87-95. PMID 22138392 DOI: 10.1016/J.Pneurobio.2011.11.005 |
0.366 |
|
| 2012 |
Leinonen V, Koivisto AM, Savolainen S, Rummukainen J, Sutela A, Vanninen R, Jääskeläinen JE, Soininen H, Alafuzoff I. Post-mortem findings in 10 patients with presumed normal-pressure hydrocephalus and review of the literature. Neuropathology and Applied Neurobiology. 38: 72-86. PMID 21696417 DOI: 10.1111/J.1365-2990.2011.01195.X |
0.391 |
|
| 2012 |
Hartikainen PH, Pikkarainen M, Hänninen T, Soininen H, Alafuzoff I. Unusual clinical presentation and neuropathology in two subjects with fused-in sarcoma (FUS) positive inclusions. Neuropathology : Official Journal of the Japanese Society of Neuropathology. 32: 60-8. PMID 21518013 DOI: 10.1111/J.1440-1789.2011.01218.X |
0.348 |
|
| 2012 |
Seppälä T, Nerg O, Koivisto A, Rummukainen J, Puli L, Zetterberg H, Pyykkö O, Helisalmi S, Alafuzoff I, Hiltunen M, Jääskeläinen J, Rinne J, Soininen H, Leinonen V, Herukka S. Cerebrospinal fluid biomarkers for Alzheimer's disease are associated with neuropathology in cortical brain biopsy Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.202 |
0.403 |
|
| 2011 |
Pikkarainen M, Hartikainen P, Soininen H, Alafuzoff I. Distribution and pattern of pathology in subjects with familial or sporadic late-onset cerebellar ataxia as assessed by p62/sequestosome immunohistochemistry. Cerebellum (London, England). 10: 720-31. PMID 21544590 DOI: 10.1007/S12311-011-0281-2 |
0.35 |
|
| 2011 |
Giaccone G, Arzberger T, Alafuzoff I, Al-Sarraj S, Budka H, Duyckaerts C, Falkai P, Ferrer I, Ironside JW, Kovács GG, Meyronet D, Parchi P, Patsouris E, Revesz T, Riederer P, et al. New lexicon and criteria for the diagnosis of Alzheimer's disease. The Lancet. Neurology. 10: 298-9; author reply . PMID 21435593 DOI: 10.1016/S1474-4422(11)70055-2 |
0.368 |
|
| 2011 |
Rauramaa T, Pikkarainen M, Englund E, Ince PG, Jellinger K, Paetau A, Alafuzoff I. TAR-DNA binding protein-43 and alterations in the hippocampus. Journal of Neural Transmission (Vienna, Austria : 1996). 118: 683-9. PMID 21210283 DOI: 10.1007/S00702-010-0574-5 |
0.389 |
|
| 2011 |
Rauramaa T, Pikkarainen M, Englund E, Ince PG, Jellinger K, Paetau A, Parkkinen L, Alafuzoff I. Cardiovascular diseases and hippocampal infarcts. Hippocampus. 21: 281-7. PMID 20054813 DOI: 10.1002/Hipo.20747 |
0.301 |
|
| 2011 |
Rummukainen J, Koivisto AM, Alafuzoff I, Leinonen V. Amyloid-β and Hyperphosphorylated Tau in the Prediction of Alzheimer’s Disease European Neurological Review. 6: 84. DOI: 10.17925/Enr.2011.06.02.84 |
0.347 |
|
| 2011 |
Leinonen V, Koivisto AM, Savolainen S, Rummukainen J, Sutela A, Vanninen R, Soininen H, Alafuzoff I. Post-mortem beta-amyloid plaques correlate with frontal cortical biopsy findings Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.2036 |
0.307 |
|
| 2010 |
Leinonen V, Koivisto AM, Savolainen S, Rummukainen J, Tamminen JN, Tillgren T, Vainikka S, Pyykkö OT, Mölsä J, Fraunberg M, Pirttilä T, Jääskeläinen JE, Soininen H, Rinne J, Alafuzoff I. Amyloid and tau proteins in cortical brain biopsy and Alzheimer's disease. Annals of Neurology. 68: 446-53. PMID 20976765 DOI: 10.1002/Ana.22100 |
0.397 |
|
| 2010 |
Hanisch K, Soininen H, Alafuzoff I, Hoffmann R. Analysis of human tau in cerebrospinal fluid. Journal of Proteome Research. 9: 1476-82. PMID 20067323 DOI: 10.1021/Pr901002T |
0.415 |
|
| 2010 |
Pikkarainen M, Martikainen P, Alafuzoff I. The effect of prolonged fixation time on immunohistochemical staining of common neurodegenerative disease markers. Journal of Neuropathology and Experimental Neurology. 69: 40-52. PMID 20010304 DOI: 10.1097/Nen.0B013E3181C6C13D |
0.326 |
|
| 2010 |
Mackenzie IR, Neumann M, Bigio EH, Cairns NJ, Alafuzoff I, Kril J, Kovacs GG, Ghetti B, Halliday G, Holm IE, Ince PG, Kamphorst W, Revesz T, Rozemuller AJ, Kumar-Singh S, et al. Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update. Acta Neuropathologica. 119: 1-4. PMID 19924424 DOI: 10.1007/S00401-009-0612-2 |
0.312 |
|
| 2010 |
Martikainen P, Pikkarainen M, Pöntynen K, Hiltunen M, Lehtovirta M, Tuisku S, Soininen H, Alafuzoff I. Brain pathology in three subjects from the same pedigree with presenilin-1 (PSEN1) P264L mutation. Neuropathology and Applied Neurobiology. 36: 41-54. PMID 19849793 DOI: 10.1111/J.1365-2990.2009.01046.X |
0.375 |
|
| 2010 |
Leinonen V, Koivisto AM, Rummukainen J, Tamminen J, Tillgren T, Vainikka S, Savolainen S, Pyykkö O, Fraunberg M, Pirttilä T, Jääskeläinen JE, Soininen H, Rinne J, Alafuzoff I. O2-02-01: Prediction of Alzheimer's disease by beta-amyloid plaques and tau protein in frontal cortical biopsy Alzheimer's & Dementia. 6: S97-S97. DOI: 10.1016/J.Jalz.2010.05.306 |
0.378 |
|
| 2009 |
Singer D, Soininen H, Alafuzoff I, Hoffmann R. Immuno-PCR-based quantification of multiple phosphorylated tau-epitopes linked to Alzheimer's disease. Analytical and Bioanalytical Chemistry. 395: 2263-7. PMID 19821112 DOI: 10.1007/S00216-009-3208-8 |
0.321 |
|
| 2009 |
Grünblatt E, Monoranu CM, Apfelbacher M, Keller D, Michel TM, Alafuzoff I, Ferrer I, Al-Saraj S, Keyvani K, Schmitt A, Falkai P, Schittenhelm J, McLean C, Halliday GM, Harper C, et al. Tryptophan is a marker of human postmortem brain tissue quality. Journal of Neurochemistry. 110: 1400-8. PMID 19545279 DOI: 10.1111/J.1471-4159.2009.06233.X |
0.322 |
|
| 2009 |
Monoranu CM, Apfelbacher M, Grünblatt E, Puppe B, Alafuzoff I, Ferrer I, Al-Saraj S, Keyvani K, Schmitt A, Falkai P, Schittenhelm J, Halliday G, Kril J, Harper C, McLean C, et al. pH measurement as quality control on human post mortem brain tissue: a study of the BrainNet Europe consortium. Neuropathology and Applied Neurobiology. 35: 329-37. PMID 19473297 DOI: 10.1111/J.1365-2990.2008.01003A.X |
0.324 |
|
| 2009 |
Pikkarainen M, Kauppinen T, Alafuzoff I. Hyperphosphorylated tau in the occipital cortex in aged nondemented subjects. Journal of Neuropathology and Experimental Neurology. 68: 653-60. PMID 19458543 DOI: 10.1097/Nen.0B013E3181A6Ee45 |
0.364 |
|
| 2009 |
Aho L, Karkola K, Juusela J, Alafuzoff I. Heavy alcohol consumption and neuropathological lesions: a post-mortem human study. Journal of Neuroscience Research. 87: 2786-92. PMID 19382227 DOI: 10.1002/Jnr.22091 |
0.349 |
|
| 2009 |
Tapiola T, Alafuzoff I, Herukka SK, Parkkinen L, Hartikainen P, Soininen H, Pirttilä T. Cerebrospinal fluid {beta}-amyloid 42 and tau proteins as biomarkers of Alzheimer-type pathologic changes in the brain. Archives of Neurology. 66: 382-9. PMID 19273758 DOI: 10.1001/Archneurol.2008.596 |
0.433 |
|
| 2009 |
Alafuzoff I, Thal DR, Arzberger T, Bogdanovic N, Al-Sarraj S, Bodi I, Boluda S, Bugiani O, Duyckaerts C, Gelpi E, Gentleman S, Giaccone G, Graeber M, Hortobagyi T, Höftberger R, et al. Assessment of beta-amyloid deposits in human brain: a study of the BrainNet Europe Consortium. Acta Neuropathologica. 117: 309-20. PMID 19184666 DOI: 10.1007/S00401-009-0485-4 |
0.335 |
|
| 2009 |
Mackenzie IR, Neumann M, Bigio EH, Cairns NJ, Alafuzoff I, Kril J, Kovacs GG, Ghetti B, Halliday G, Holm IE, Ince PG, Kamphorst W, Revesz T, Rozemuller AJ, Kumar-Singh S, et al. Nomenclature for neuropathologic subtypes of frontotemporal lobar degeneration: consensus recommendations. Acta Neuropathologica. 117: 15-8. PMID 19015862 DOI: 10.1007/S00401-008-0460-5 |
0.311 |
|
| 2009 |
Seppänen A, Pikkarainen M, Hartikainen P, Hofmann SC, Majamaa K, Alafuzoff I. Expression of collagen XVII and ubiquitin-binding protein p62 in motor neuron disease. Brain Research. 1247: 171-7. PMID 18992722 DOI: 10.1016/J.Brainres.2008.10.020 |
0.323 |
|
| 2009 |
Alafuzoff I, Aho L, Helisalmi S, Mannermaa A, Soininen H. Beta-amyloid deposition in brains of subjects with diabetes. Neuropathology and Applied Neurobiology. 35: 60-8. PMID 18346114 DOI: 10.1111/J.1365-2990.2008.00948.X |
0.36 |
|
| 2009 |
Ojala J, Alafuzoff I, Herukka SK, van Groen T, Tanila H, Pirttilä T. Expression of interleukin-18 is increased in the brains of Alzheimer's disease patients. Neurobiology of Aging. 30: 198-209. PMID 17658666 DOI: 10.1016/J.Neurobiolaging.2007.06.006 |
0.328 |
|
| 2008 |
Kovacs GG, Alafuzoff I, Al-Sarraj S, Arzberger T, Bogdanovic N, Capellari S, Ferrer I, Gelpi E, Kövari V, Kretzschmar H, Nagy Z, Parchi P, Seilhean D, Soininen H, Troakes C, et al. Mixed brain pathologies in dementia: the BrainNet Europe consortium experience. Dementia and Geriatric Cognitive Disorders. 26: 343-50. PMID 18849605 DOI: 10.1159/000161560 |
0.435 |
|
| 2008 |
Hansson Petersen CA, Alikhani N, Behbahani H, Wiehager B, Pavlov PF, Alafuzoff I, Leinonen V, Ito A, Winblad B, Glaser E, Ankarcrona M. The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae. Proceedings of the National Academy of Sciences of the United States of America. 105: 13145-50. PMID 18757748 DOI: 10.1073/Pnas.0806192105 |
0.312 |
|
| 2008 |
Leinonen V, Alafuzoff I, Aalto S, Suotunen T, Savolainen S, Någren K, Tapiola T, Pirttilä T, Rinne J, Jääskeläinen JE, Soininen H, Rinne JO. Assessment of beta-amyloid in a frontal cortical brain biopsy specimen and by positron emission tomography with carbon 11-labeled Pittsburgh Compound B. Archives of Neurology. 65: 1304-9. PMID 18695050 DOI: 10.1001/Archneur.65.10.Noc80013 |
0.366 |
|
| 2008 |
Alafuzoff I. Cerebral amyloid angiopathy, hemorrhages and superficial siderosis. Stroke; a Journal of Cerebral Circulation. 39: 2699-700. PMID 18635839 DOI: 10.1161/Strokeaha.108.516955 |
0.393 |
|
| 2008 |
Aho L, Parkkinen L, Pirttila T, Alafuzoff I. Systematic appraisal using immunohistochemistry of brain pathology in aged and demented subjects. Dementia and Geriatric Cognitive Disorders. 25: 423-32. PMID 18391488 DOI: 10.1159/000122963 |
0.416 |
|
| 2008 |
Pikkarainen M, Hartikainen P, Alafuzoff I. Neuropathologic features of frontotemporal lobar degeneration with ubiquitin-positive inclusions visualized with ubiquitin-binding protein p62 immunohistochemistry. Journal of Neuropathology and Experimental Neurology. 67: 280-98. PMID 18379439 DOI: 10.1097/Nen.0B013E31816A1Da2 |
0.345 |
|
| 2008 |
Alafuzoff I, Arzberger T, Al-Sarraj S, Bodi I, Bogdanovic N, Braak H, Bugiani O, Del-Tredici K, Ferrer I, Gelpi E, Giaccone G, Graeber MB, Ince P, Kamphorst W, King A, et al. Staging of neurofibrillary pathology in Alzheimer's disease: a study of the BrainNet Europe Consortium. Brain Pathology (Zurich, Switzerland). 18: 484-96. PMID 18371174 DOI: 10.1111/J.1750-3639.2008.00147.X |
0.428 |
|
| 2008 |
Bell JE, Alafuzoff I, Al-Sarraj S, Arzberger T, Bogdanovic N, Budka H, Dexter DT, Falkai P, Ferrer I, Gelpi E, Gentleman SM, Giaccone G, Huitinga I, Ironside JW, Klioueva N, et al. Management of a twenty-first century brain bank: experience in the BrainNet Europe consortium. Acta Neuropathologica. 115: 497-507. PMID 18365220 DOI: 10.1007/S00401-008-0360-8 |
0.312 |
|
| 2008 |
Alafuzoff I, Pikkarainen M, Arzberger T, Thal DR, Al-Sarraj S, Bell J, Bodi I, Budka H, Capetillo-Zarate E, Ferrer I, Gelpi E, Gentleman S, Giaccone G, Kavantzas N, King A, et al. Inter-laboratory comparison of neuropathological assessments of beta-amyloid protein: a study of the BrainNet Europe consortium. Acta Neuropathologica. 115: 533-46. PMID 18343933 DOI: 10.1007/S00401-008-0358-2 |
0.326 |
|
| 2008 |
Parkkinen L, Pirttilä T, Alafuzoff I. Applicability of current staging/categorization of alpha-synuclein pathology and their clinical relevance. Acta Neuropathologica. 115: 399-407. PMID 18297293 DOI: 10.1007/S00401-008-0346-6 |
0.347 |
|
| 2008 |
Kuusisto E, Kauppinen T, Alafuzoff I. Use of p62/SQSTM1 antibodies for neuropathological diagnosis. Neuropathology and Applied Neurobiology. 34: 169-80. PMID 17961133 DOI: 10.1111/J.1365-2990.2007.00884.X |
0.361 |
|
| 2008 |
Herukka S, Tapiola T, Hallikainen M, Tervo S, Helisalmi S, Pennanen C, Alafuzoff I, Soininen H, Pirttilä T. P3-073: CSF Aβ42, Tau and phosphorylated Tau are biomarkers for Alzheimer's disease neuropathology and predict development of Alzheimer's disease in patients with mild cognitive impairment Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1637 |
0.415 |
|
| 2007 |
Seppänen A, Suuronen T, Hofmann SC, Majamaa K, Alafuzoff I. Distribution of collagen XVII in the human brain. Brain Research. 1158: 50-6. PMID 17555727 DOI: 10.1016/J.Brainres.2007.04.073 |
0.338 |
|
| 2007 |
Schmitt A, Bauer M, Heinsen H, Feiden W, Falkai P, Alafuzoff I, Arzberger T, Al-Sarraj S, Bell JE, Bogdanovic N, Brück W, Budka H, Ferrer I, Giaccone G, et al. How a neuropsychiatric brain bank should be run: a consensus paper of Brainnet Europe II. Journal of Neural Transmission (Vienna, Austria : 1996). 114: 527-37. PMID 17165101 DOI: 10.1007/S00702-006-0601-8 |
0.325 |
|
| 2006 |
Aho L, Jolkkonen J, Alafuzoff I. Beta-amyloid aggregation in human brains with cerebrovascular lesions. Stroke; a Journal of Cerebral Circulation. 37: 2940-5. PMID 17095738 DOI: 10.1161/01.Str.0000248777.44128.93 |
0.33 |
|
| 2006 |
Buerger K, Ewers M, Pirttilä T, Zinkowski R, Alafuzoff I, Teipel SJ, DeBernardis J, Kerkman D, McCulloch C, Soininen H, Hampel H. CSF phosphorylated tau protein correlates with neocortical neurofibrillary pathology in Alzheimer's disease. Brain : a Journal of Neurology. 129: 3035-41. PMID 17012293 DOI: 10.1093/Brain/Awl269 |
0.416 |
|
| 2006 |
Braak H, Alafuzoff I, Arzberger T, Kretzschmar H, Del Tredici K. Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry. Acta Neuropathologica. 112: 389-404. PMID 16906426 DOI: 10.1007/S00401-006-0127-Z |
0.396 |
|
| 2006 |
Alafuzoff I, Pikkarainen M, Al-Sarraj S, Arzberger T, Bell J, Bodi I, Bogdanovic N, Budka H, Bugiani O, Ferrer I, Gelpi E, Giaccone G, Graeber MB, Hauw JJ, Kamphorst W, et al. Interlaboratory comparison of assessments of Alzheimer disease-related lesions: a study of the BrainNet Europe Consortium. Journal of Neuropathology and Experimental Neurology. 65: 740-57. PMID 16896308 DOI: 10.1097/01.Jnen.0000229986.17548.27 |
0.394 |
|
| 2006 |
Martikainen P, Louhelainen AM, Kauppinen T, Alafuzoff I. Human brain tissue microarrays as a platform to investigate diseases of the nervous system. Brain Research. 1089: 33-43. PMID 16643868 DOI: 10.1016/J.Brainres.2006.03.044 |
0.451 |
|
| 2006 |
Zhou XW, Li X, Bjorkdahl C, Sjogren MJ, Alafuzoff I, Soininen H, Grundke-Iqbal I, Iqbal K, Winblad B, Pei JJ. Assessments of the accumulation severities of amyloid beta-protein and hyperphosphorylated tau in the medial temporal cortex of control and Alzheimer's brains. Neurobiology of Disease. 22: 657-68. PMID 16513361 DOI: 10.1016/J.Nbd.2006.01.006 |
0.426 |
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| 2006 |
Korolainen MA, Goldsteins G, Nyman TA, Alafuzoff I, Koistinaho J, Pirttilä T. Oxidative modification of proteins in the frontal cortex of Alzheimer's disease brain. Neurobiology of Aging. 27: 42-53. PMID 16298240 DOI: 10.1016/J.Neurobiolaging.2004.11.010 |
0.372 |
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| 2006 |
Vepsäläinen S, Hiltunen M, Helisalmi S, Tanila H, Wang J, Groen Tv, Alafuzoff I, Ojala J, Soininen H. AbstractPoster presentation: Sunday posterP1-300: Age and brain region specific alterations in mRNA levels of Aβ-degrading enzymes; IDE and NEP Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.677 |
0.315 |
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| 2006 |
Liu R, Björkdahl C, Zhou X, Alafuzoff I, Soininen H, Bogdanovic N, Iqbal K, Grundke-Iqbal I, Winblad BW, Wang J, Pei J. P3-300: Increased tyrosine 307 phosphorylation of protein phosphatase-2A correlates with tau associated pathologies in Alzheimer’s disease Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1569 |
0.33 |
|
| 2006 |
Ojala J, Alafuzoff I, Herukka S, Pirttilä T. P3-271: Expression of interleukin 18 is increased in the brain of Alzheimer’s disease patients Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1540 |
0.356 |
|
| 2006 |
Pikkarainen M, Alafuzoff I, Kretzschmar H. P3-186: Inter-laboratory reproducibility of silver and immunohistochemical assessments of Alzheimer's disease related lesions. A study of the BrainNet Europe Consortium Alzheimer's & Dementia. 2: S429-S430. DOI: 10.1016/J.Jalz.2006.05.1454 |
0.366 |
|
| 2005 |
Parkkinen L, Pirttilä T, Tervahauta M, Alafuzoff I. Widespread and abundant alpha-synuclein pathology in a neurologically unimpaired subject. Neuropathology : Official Journal of the Japanese Society of Neuropathology. 25: 304-14. PMID 16382779 DOI: 10.1111/J.1440-1789.2005.00644.X |
0.407 |
|
| 2005 |
Iqbal K, Flory M, Khatoon S, Soininen H, Pirttila T, Lehtovirta M, Alafuzoff I, Blennow K, Andreasen N, Vanmechelen E, Grundke-Iqbal I. Subgroups of Alzheimer's disease based on cerebrospinal fluid molecular markers. Annals of Neurology. 58: 748-57. PMID 16247771 DOI: 10.1002/Ana.20639 |
0.42 |
|
| 2005 |
Li X, Alafuzoff I, Soininen H, Winblad B, Pei JJ. Levels of mTOR and its downstream targets 4E-BP1, eEF2, and eEF2 kinase in relationships with tau in Alzheimer's disease brain. The Febs Journal. 272: 4211-20. PMID 16098202 DOI: 10.1111/J.1742-4658.2005.04833.X |
0.426 |
|
| 2005 |
Korolainen MA, Auriola S, Nyman TA, Alafuzoff I, Pirttilä T. Proteomic analysis of glial fibrillary acidic protein in Alzheimer's disease and aging brain. Neurobiology of Disease. 20: 858-70. PMID 15979880 DOI: 10.1016/J.Nbd.2005.05.021 |
0.434 |
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| 2005 |
Parkkinen L, Kauppinen T, Pirttilä T, Autere JM, Alafuzoff I. Alpha-synuclein pathology does not predict extrapyramidal symptoms or dementia. Annals of Neurology. 57: 82-91. PMID 15562510 DOI: 10.1002/Ana.20321 |
0.331 |
|
| 2004 |
Helisalmi S, Hiltunen M, Vepsäläinen S, Iivonen S, Mannermaa A, Lehtovirta M, Koivisto AM, Alafuzoff I, Soininen H. Polymorphisms in neprilysin gene affect the risk of Alzheimer's disease in Finnish patients. Journal of Neurology, Neurosurgery, and Psychiatry. 75: 1746-8. PMID 15548496 DOI: 10.1136/Jnnp.2004.036574 |
0.35 |
|
| 2004 |
Li X, An WL, Alafuzoff I, Soininen H, Winblad B, Pei JJ. Phosphorylated eukaryotic translation factor 4E is elevated in Alzheimer brain. Neuroreport. 15: 2237-40. PMID 15371741 DOI: 10.1097/00001756-200410050-00019 |
0.391 |
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| 2004 |
Kanninen K, Goldsteins G, Auriola S, Alafuzoff I, Koistinaho J. Glycosylation changes in Alzheimer's disease as revealed by a proteomic approach. Neuroscience Letters. 367: 235-40. PMID 15331161 DOI: 10.1016/J.Neulet.2004.06.013 |
0.384 |
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| 2004 |
Korolainen MA, Auriola S, Nyman T, Alafuzoff I, Pirttilä T. P4-216 Proteomic analysis of glial fibrillary acidic protein in Alzheimer's disease brain Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81774-3 |
0.392 |
|
| 2004 |
An W, Cowburn RF, Bjorkdahl C, Braak H, Alafuzoff I, Iqbal K, Grundke-Iqbal I, Winblad B. P3-246 Association of P70 S6 kinase with neurofibrillary degeneration in Alzheimer's disease Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81396-4 |
0.342 |
|
| 2003 |
Iivonen S, Helisalmi S, Mannermaa A, Alafuzoff I, Lehtovirta M, Soininen H, Hiltunen M. Heparan sulfate proteoglycan 2 polymorphism in Alzheimer's disease and correlation with neuropathology. Neuroscience Letters. 352: 146-50. PMID 14625044 DOI: 10.1016/J.Neulet.2003.08.041 |
0.37 |
|
| 2003 |
An WL, Cowburn RF, Li L, Braak H, Alafuzoff I, Iqbal K, Iqbal IG, Winblad B, Pei JJ. Up-regulation of phosphorylated/activated p70 S6 kinase and its relationship to neurofibrillary pathology in Alzheimer's disease. The American Journal of Pathology. 163: 591-607. PMID 12875979 DOI: 10.1016/S0002-9440(10)63687-5 |
0.343 |
|
| 2003 |
Riedel A, Miettinen R, Stieler J, Mikkonen M, Alafuzoff I, Soininen H, Arendt T. Reelin-immunoreactive Cajal-Retzius cells: the entorhinal cortex in normal aging and Alzheimer's disease. Acta Neuropathologica. 106: 291-302. PMID 12811583 DOI: 10.1007/S00401-003-0729-7 |
0.406 |
|
| 2003 |
Parkkinen L, Soininen H, Alafuzoff I. Regional distribution of alpha-synuclein pathology in unimpaired aging and Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 62: 363-7. PMID 12722828 DOI: 10.1093/Jnen/62.4.363 |
0.42 |
|
| 2003 |
Pei JJ, Khatoon S, An WL, Nordlinder M, Tanaka T, Braak H, Tsujio I, Takeda M, Alafuzoff I, Winblad B, Cowburn RF, Grundke-Iqbal I, Iqbal K. Role of protein kinase B in Alzheimer's neurofibrillary pathology. Acta Neuropathologica. 105: 381-92. PMID 12624792 DOI: 10.1007/S00401-002-0657-Y |
0.432 |
|
| 2003 |
Mattila KM, Hiltunen M, Rinne JO, Mannermaa A, Röyttä M, Alafuzoff I, Laippala P, Soininen H, Lehtimäki T. Absence of association between an intercellular adhesion molecule 1 gene E469K polymorphism and Alzheimer's disease in Finnish patients. Neuroscience Letters. 337: 61-3. PMID 12524171 DOI: 10.1016/S0304-3940(02)01296-X |
0.355 |
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| 2002 |
Korolainen MA, Goldsteins G, Alafuzoff I, Koistinaho J, Pirttilä T. Proteomic analysis of protein oxidation in Alzheimer's disease brain. Electrophoresis. 23: 3428-33. PMID 12373773 DOI: 10.1002/1522-2683(200210)23:19<3428::Aid-Elps3428>3.0.Co;2-5 |
0.318 |
|
| 2002 |
Pirskanen M, Hiltunen M, Mannermaa A, Iivonen S, Helisalmi S, Lehtovirta M, Koivisto AM, Laakso M, Soininen H, Alafuzoff I. Interleukin 1 alpha gene polymorphism as a susceptibility factor in Alzheimer's disease and its influence on the extent of histopathological hallmark lesions of Alzheimer's disease. Dementia and Geriatric Cognitive Disorders. 14: 123-7. PMID 12218254 DOI: 10.1159/000063603 |
0.394 |
|
| 2002 |
Iivonen S, Hiltunen M, Alafuzoff I, Mannermaa A, Kerokoski P, Puoliväli J, Salminen A, Helisalmi S, Soininen H. Seladin-1 transcription is linked to neuronal degeneration in Alzheimer's disease. Neuroscience. 113: 301-10. PMID 12127087 DOI: 10.1016/S0306-4522(02)00180-X |
0.399 |
|
| 2002 |
Kuusisto E, Salminen A, Alafuzoff I. Early accumulation of p62 in neurofibrillary tangles in Alzheimer's disease: possible role in tangle formation. Neuropathology and Applied Neurobiology. 28: 228-37. PMID 12060347 DOI: 10.1046/J.1365-2990.2002.00394.X |
0.392 |
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| 2001 |
Mikkonen M, Soininen H, Alafuzoff I, Miettinen R. Hippocampal plasticity in Alzheimer's disease. Reviews in the Neurosciences. 12: 311-326. PMID 11783717 DOI: 10.1515/Revneuro.2001.12.4.311 |
0.44 |
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| 2001 |
Laitinen KS, van Groen T, Tanila H, Venäläinen J, Männistö PT, Alafuzoff I. Brain prolyl oligopeptidase activity is associated with neuronal damage rather than beta-amyloid accumulation. Neuroreport. 12: 3309-12. PMID 11711876 DOI: 10.1097/00001756-200110290-00032 |
0.388 |
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| 2001 |
Parkkinen L, Soininen H, Laakso M, Alafuzoff I. Alpha-synuclein pathology is highly dependent on the case selection. Neuropathology and Applied Neurobiology. 27: 314-25. PMID 11532162 DOI: 10.1046/J.0305-1846.2001.00342.X |
0.339 |
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| 2001 |
Pirskanen M, Alafuzoff I, Hiltunen M, Mannermaa A, Helisalmi S, Lehtovirta M, Koivisto AM, Laakso M, Soininen H. An association between a subset of Finnish late-onset Alzheimer's disease and alpha2-macroglobulin. Neurogenetics. 3: 171-2. PMID 11523569 DOI: 10.1007/S100480100110 |
0.342 |
|
| 2001 |
Kuusisto E, Salminen A, Alafuzoff I. Ubiquitin-binding protein p62 is present in neuronal and glial inclusions in human tauopathies and synucleinopathies. Neuroreport. 12: 2085-90. PMID 11447312 DOI: 10.1097/00001756-200107200-00009 |
0.373 |
|
| 2001 |
Kraszpulski M, Soininen H, Helisalmi S, Alafuzoff I. The load and distribution of beta-amyloid in brain tissue of patients with Alzheimer's disease. Acta Neurologica Scandinavica. 103: 88-92. PMID 11227137 DOI: 10.1034/J.1600-0404.2001.103002088.X |
0.403 |
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| 2001 |
Savolainen S, Karhu J, Pääkkönen A, Paljärvi L, Partanen J, Alafuzoff I, Vapalahti M. Auditory event-related potentials differentiate patients with normal pressure hydrocephalus and patients with concomitant Alzheimer's disease verified by brain biopsy. Neuroreport. 12: 33-7. PMID 11201087 DOI: 10.1097/00001756-200101220-00015 |
0.389 |
|
| 2000 |
Alafuzoff I, Overmyer M, Helisalmi S, Soininen H. Lower Counts of Astroglia and Activated Microglia in Patients with Alzheimer's Disease with Regular Use of Non-Steroidal Anti-Inflammatory Drugs. Journal of Alzheimer's Disease : Jad. 2: 37-46. PMID 12214109 DOI: 10.3233/Jad-2000-2105 |
0.382 |
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| 2000 |
Reynolds WF, Hiltunen M, Pirskanen M, Mannermaa A, Helisalmi S, Lehtovirta M, Alafuzoff I, Soininen H. MPO and APOEepsilon4 polymorphisms interact to increase risk for AD in Finnish males. Neurology. 55: 1284-90. PMID 11087769 DOI: 10.1212/Wnl.55.9.1284 |
0.342 |
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| 2000 |
Overmyer M, Kraszpulski M, Helisalmi S, Soininen H, Alafuzoff I. DNA fragmentation, gliosis and histological hallmarks of Alzheimer's disease. Acta Neuropathologica. 100: 681-7. PMID 11078220 DOI: 10.1007/S004010000228 |
0.425 |
|
| 2000 |
Tapiola T, Pirttilä T, Mehta PD, Alafuzoff I, Lehtovirta M, Soininen H. Relationship between apoE genotype and CSF β-amyloid (1-42) and tau in patients with probable and definite Alzheimer's disease Neurobiology of Aging. 21: 735-740. PMID 11016543 DOI: 10.1016/S0197-4580(00)00164-0 |
0.419 |
|
| 2000 |
Hiltunen M, Helisalmi S, Mannermaa A, Alafuzoff I, Koivisto AM, Lehtovirta M, Pirskanen M, Sulkava R, Verkkoniemi A, Soininen H. Identification of a novel 4.6-kb genomic deletion in presenilin-1 gene which results in exclusion of exon 9 in a Finnish early onset Alzheimer's disease family: an Alu core sequence-stimulated recombination? European Journal of Human Genetics : Ejhg. 8: 259-66. PMID 10854108 DOI: 10.1038/Sj.Ejhg.5200423 |
0.304 |
|
| 2000 |
Alafuzoff I, Helisalmi S, Mannermaa A, Soininen H. Severity of cardiovascular disease, apolipoprotein E genotype, and brain pathology in aging and dementia. Annals of the New York Academy of Sciences. 903: 244-51. PMID 10818513 DOI: 10.1111/J.1749-6632.2000.Tb06374.X |
0.399 |
|
| 2000 |
Alafuzoff I, Helisalmi S, Heinonen EH, Reinikainen K, Hallikainen M, Soininen H, Koivisto K. Selegiline treatment and the extent of degenerative changes in brain tissue of patients with Alzheimer's disease. European Journal of Clinical Pharmacology. 55: 815-9. PMID 10805059 DOI: 10.1007/S002280050702 |
0.426 |
|
| 2000 |
Tapiola T, Pirttilä T, Mikkonen M, Mehta PD, Alafuzoff I, Koivisto K, Soininen H. Three-year follow-up of cerebrospinal fluid tau, beta-amyloid 42 and 40 concentrations in Alzheimer's disease. Neuroscience Letters. 280: 119-22. PMID 10686392 DOI: 10.1016/S0304-3940(00)00767-9 |
0.428 |
|
| 2000 |
Helisalmi S, Hiltunen M, Mannermaa A, Koivisto AM, Lehtovirta M, Alafuzoff I, Ryynänen M, Soininen H. Is the presenilin-1 E318G missense mutation a risk factor for Alzheimer's disease? Neuroscience Letters. 278: 65-8. PMID 10643802 DOI: 10.1016/S0304-3940(99)00891-5 |
0.338 |
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| 1999 |
Mikkonen M, Alafuzoff I, Tapiola T, Soininen H, Miettinen R. Subfield- and layer-specific changes in parvalbumin, calretinin and calbindin-D28K immunoreactivity in the entorhinal cortex in Alzheimer's disease. Neuroscience. 92: 515-32. PMID 10408601 DOI: 10.1016/S0306-4522(99)00047-0 |
0.385 |
|
| 1999 |
Overmyer M, Helisalmi S, Soininen H, Laakso M, Riekkinen P, Alafuzoff I. Astrogliosis and the ApoE genotype. an immunohistochemical study of postmortem human brain tissue. Dementia and Geriatric Cognitive Disorders. 10: 252-7. PMID 10364641 DOI: 10.1159/000017128 |
0.387 |
|
| 1999 |
Mikkonen M, Soininen H, Tapiola T, Alafuzoff I, Miettinen R. Hippocampal plasticity in Alzheimer's disease: changes in highly polysialylated NCAM immunoreactivity in the hippocampal formation. The European Journal of Neuroscience. 11: 1754-64. PMID 10215928 DOI: 10.1046/J.1460-9568.1999.00593.X |
0.37 |
|
| 1999 |
Overmyer M, Helisalmi S, Soininen H, Laakso M, Riekkinen P, Alafuzoff I. Reactive microglia in aging and dementia: an immunohistochemical study of postmortem human brain tissue. Acta Neuropathologica. 97: 383-92. PMID 10208278 DOI: 10.1007/S004010051002 |
0.373 |
|
| 1998 |
Kraszpulski M, Soininen H, Riekkinen P, Alafuzoff I. Pitfalls in the quantitative estimation of beta-amyloid immunoreactivity in human brain tissue. Histochemistry and Cell Biology. 110: 439-45. PMID 9792423 DOI: 10.1007/S004180050305 |
0.317 |
|
| 1998 |
Tapiola T, Lehtovirta M, Pirttilä T, Alafuzoff I, Riekkinen P, Soininen H. Increased aspartate aminotransferase activity in cerebrospinal fluid and Alzheimer's disease. Lancet. 352: 287. PMID 9690413 DOI: 10.1016/S0140-6736(05)60260-7 |
0.371 |
|
| 1997 |
Tapiola T, Overmyer M, Lehtovirta M, Helisalmi S, Ramberg J, Alafuzoff I, Riekkinen P, Soininen H. The level of cerebrospinal fluid tau correlates with neurofibrillary tangles in Alzheimer's disease. Neuroreport. 8: 3961-3. PMID 9462474 DOI: 10.1097/00001756-199712220-00022 |
0.425 |
|
| 1992 |
Cowburn RF, O'Neill C, Ravid R, Alafuzoff I, Winblad B, Fowler CJ. Adenylyl cyclase activity in postmortem human brain: evidence of altered G protein mediation in Alzheimer's disease. Journal of Neurochemistry. 58: 1409-19. PMID 1548475 DOI: 10.1111/J.1471-4159.1992.Tb11357.X |
0.362 |
|
| 1992 |
Svensson A, Alafuzoff I, Nordberg A. Characterization of muscarinic receptor subtypes in Alzheimer brains Neurobiology of Aging. 13: S132. DOI: 10.1016/0197-4580(92)90649-I |
0.345 |
|
| 1992 |
O'Neill C, Cowburn RF, Fowler CJ, Alafuzoff I, Winblad B. G protein receptor coupling in the Alzheimer's disease brain Neurochemistry International. 21. DOI: 10.1016/0197-0186(92)91958-Y |
0.358 |
|
| 1991 |
O'Neill C, Cowburn RF, Wiehager B, Alafuzoff I, Winblad B, Fowler CJ. Preservation of 5-hydroxytryptamine1A receptor-G protein interactions in the cerebral cortex of patients with Alzheimer's disease. Neuroscience Letters. 133: 15-9. PMID 1838799 DOI: 10.1016/0304-3940(91)90046-V |
0.33 |
|
| 1991 |
Bergström L, Garlind A, Nilsson L, Alafuzoff I, Fowler CJ, Winblad B, Cowburn RF. Regional distribution of somatostatin receptor binding and modulation of adenylyl cyclase activity in Alzheimer's disease brain. Journal of the Neurological Sciences. 105: 225-33. PMID 1684616 DOI: 10.1016/0022-510X(91)90149-2 |
0.373 |
|
| 1991 |
O'Neill C, Fowler CJ, Wiehager B, Cowburn RF, Alafuzoff I, Winblad B. Coupling of human brain cerebral cortical alpha 2-adrenoceptors to GTP-binding proteins in Alzheimer's disease. Brain Research. 563: 39-43. PMID 1664776 DOI: 10.1016/0006-8993(91)91512-Y |
0.331 |
|
| 1991 |
Cowburn RF, Fowler CJ, Garlind A, Alafuzoff I, Nilsson L, Winblad B, Bergström L. Somatostatin receptors and the modulation of adenylyl cyclase activity in Alzheimer's disease. Journal of Neurology, Neurosurgery, and Psychiatry. 54: 748-9. PMID 1658238 DOI: 10.1136/Jnnp.54.8.748 |
0.326 |
|
| 1990 |
Nilsson E, Alafuzoff I, Blennow K, Blomgren K, Hall CM, Janson I, Karlsson I, Wallin A, Gottfries CG, Karlsson JO. Calpain and calpastatin in normal and Alzheimer-degenerated human brain tissue. Neurobiology of Aging. 11: 425-31. PMID 2381502 DOI: 10.1016/0197-4580(90)90009-O |
0.364 |
|
| 1990 |
Allard P, Alafuzoff I, Carlsson A, Eriksson K, Ericson E, Gottfries CG, Marcusson JO. Loss of dopamine uptake sites labeled with [3H]GBR-12935 in Alzheimer's disease. European Neurology. 30: 181-5. PMID 2209670 DOI: 10.1159/000117341 |
0.369 |
|
| 1987 |
Alafuzoff I, Iqbal K, Friden H, Adolfsson R, Winblad B. Histopathological criteria for progressive dementia disorders: clinical-pathological correlation and classification by multivariate data analysis. Acta Neuropathologica. 74: 209-25. PMID 3673513 DOI: 10.1007/Bf00688184 |
0.306 |
|
| 1987 |
Marcusson JO, Alafuzoff I, Bäckström IT, Ericson E, Gottfries CG, Winblad B. 5-Hydroxytryptamine-sensitive [3H]imipramine binding of protein nature in the human brain. II. Effect of normal aging and dementia disorders. Brain Research. 425: 137-45. PMID 3427415 DOI: 10.1016/0006-8993(87)90492-6 |
0.303 |
|
| 1987 |
Alafuzoff I, Adolfsson R, Grundke-Iqbal I, Winblad B. Blood-brain barrier in Alzheimer dementia and in non-demented elderly. An immunocytochemical study. Acta Neuropathologica. 73: 160-6. PMID 3300132 DOI: 10.1007/Bf00693782 |
0.316 |
|
| 1984 |
Perdahl E, Adolfsson R, Alafuzoff I, Albert KA, Nestler EJ, Greengard P, Winblad B. Synapsin I (protein I) in different brain regions in senile dementia of Alzheimer type and in multi-infarct dementia. Journal of Neural Transmission. 60: 133-41. PMID 6436437 DOI: 10.1007/BF01245030 |
0.316 |
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