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David R. Hinton, MD FRCPC Pathol - Publications

Affiliations: 
Pathology, Neurosurgery, Ophthamology  University of Southern California, Los Angeles, CA, United States 
Area:
Aging, Gene Therapy, Vision Research, Cellular Neurobiology
Website:
http://www.usc.edu/programs/pibbs/site/faculty/hinton_d.htm

184 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Sreekumar PG, Hinton DR, Kannan R. The Emerging Role of Senescence in Ocular Disease. Oxidative Medicine and Cellular Longevity. 2020: 2583601. PMID 32215170 DOI: 10.1155/2020/2583601  0.312
2020 Shi H, Koronyo Y, Rentsendorj A, Regis GC, Sheyn J, Fuchs DT, Kramerov AA, Ljubimov AV, Dumitrascu OM, Rodriguez AR, Barron E, Hinton DR, Black KL, Miller CA, Mirzaei N, et al. Identification of early pericyte loss and vascular amyloidosis in Alzheimer's disease retina. Acta Neuropathologica. PMID 32043162 DOI: 10.1007/S00401-020-02134-W  0.308
2019 Kashani AH, Uang J, Mert M, Rahhal F, Chan C, Avery RL, Dugel P, Chen S, Lebkowski J, Clegg DO, Hinton DR, Humayun MS. Surgical Method for Implantation of a Biosynthetic Retinal Pigment Epithelium Monolayer for Geographic Atrophy: Experience from a Phase 1/2a Study. Ophthalmology. Retina. PMID 31786135 DOI: 10.1016/J.Oret.2019.09.017  0.302
2019 Li Z, Sreekumar PG, Peddi S, Hinton DR, Kannan R, MacKay JA. The humanin peptide mediates ELP nanoassembly and protects human retinal pigment epithelial cells from oxidative stress. Nanomedicine : Nanotechnology, Biology, and Medicine. 102111. PMID 31655204 DOI: 10.1016/J.Nano.2019.102111  0.608
2019 Su F, Spee C, Araujo E, Barron E, Wang M, Ghione C, Hinton DR, Nusinowitz S, Kannan R, Reddy ST, Farias-Eisner R. A Novel HDL-Mimetic Peptide HM-10/10 Protects RPE and Photoreceptors in Murine Models of Retinal Degeneration. International Journal of Molecular Sciences. 20. PMID 31569695 DOI: 10.3390/Ijms20194807  0.358
2019 Wang M, Lau LI, Sreekumar PG, Spee C, Hinton DR, Sadda SR, Kannan R. Characterization and Regulation of Carrier Proteins of Mitochondrial Glutathione Uptake in Human Retinal Pigment Epithelium Cells. Investigative Ophthalmology & Visual Science. 60: 500-516. PMID 30707752 DOI: 10.1167/Iovs.18-25686  0.319
2018 Sreekumar PG, Li Z, Wang W, Spee C, Hinton DR, Kannan R, Andrew MacKay J. Intra-vitreal αB crystallin fused to elastin-like polypeptide provides neuroprotection in a mouse model of age-related macular degeneration. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 29778783 DOI: 10.1016/J.Jconrel.2018.05.014  0.357
2018 Kashani AH, Lebkowski JS, Rahhal FM, Avery RL, Salehi-Had H, Dang W, Lin CM, Mitra D, Zhu D, Thomas BB, Hikita ST, Pennington BO, Johnson LV, Clegg DO, Hinton DR, et al. A bioengineered retinal pigment epithelial monolayer for advanced, dry age-related macular degeneration. Science Translational Medicine. 10. PMID 29618560 DOI: 10.1126/Scitranslmed.Aao4097  0.308
2017 Jiao C, Eliott D, Spee C, He S, Wang K, Mullins RF, Hinton DR, Sohn EH. APOPTOSIS AND ANGIOFIBROSIS IN DIABETIC TRACTIONAL MEMBRANES AFTER VASCULAR ENDOTHELIAL GROWTH FACTOR INHIBITION: Results of a Prospective Trial. Report No. 2. Retina (Philadelphia, Pa.). PMID 29190236 DOI: 10.1097/Iae.0000000000001952  0.312
2017 Kerur N, Fukuda S, Banerjee D, Kim Y, Fu D, Apicella I, Varshney A, Yasuma R, Fowler BJ, Baghdasaryan E, Marion KM, Huang X, Yasuma T, Hirano Y, Serbulea V, ... ... Hinton DR, et al. cGAS drives noncanonical-inflammasome activation in age-related macular degeneration. Nature Medicine. PMID 29176737 DOI: 10.1038/Nm.4450  0.341
2017 Lin TC, Seiler MJ, Zhu D, Falabella P, Hinton DR, Clegg DO, Humayun MS, Thomas BB. Assessment of Safety and Functional Efficacy of Stem Cell-Based Therapeutic Approaches Using Retinal Degenerative Animal Models. Stem Cells International. 2017: 9428176. PMID 28928775 DOI: 10.1155/2017/9428176  0.322
2017 Minasyan L, Sreekumar PG, Hinton DR, Kannan R. Protective Mechanisms of the Mitochondrial-Derived Peptide Humanin in Oxidative and Endoplasmic Reticulum Stress in RPE Cells. Oxidative Medicine and Cellular Longevity. 2017: 1675230. PMID 28814984 DOI: 10.1155/2017/1675230  0.326
2017 Sreekumar PG, Hinton DR, Kannan R. Endoplasmic reticulum-mitochondrial crosstalk: a novel role for the mitochondrial peptide humanin. Neural Regeneration Research. 12: 35-38. PMID 28250736 DOI: 10.4103/1673-5374.198970  0.308
2016 Matsunaga D, Sreekumar PG, Ishikawa K, Terasaki H, Barron E, Cohen P, Kannan R, Hinton DR. Humanin Protects RPE Cells from Endoplasmic Reticulum Stress-Induced Apoptosis by Upregulation of Mitochondrial Glutathione. Plos One. 11: e0165150. PMID 27783653 DOI: 10.1371/Journal.Pone.0165150  0.327
2016 Savarin C, Bergmann CC, Hinton DR, Stohlman SA. Differential Regulation of Self-reactive CD4(+) T Cells in Cervical Lymph Nodes and Central Nervous System during Viral Encephalomyelitis. Frontiers in Immunology. 7: 370. PMID 27708643 DOI: 10.3389/Fimmu.2016.00370  0.329
2016 Koss MJ, Falabella P, Stefanini FR, Pfister M, Thomas BB, Kashani AH, Brant R, Zhu D, Clegg DO, Hinton DR, Humayun MS. Subretinal implantation of a monolayer of human embryonic stem cell-derived retinal pigment epithelium: a feasibility and safety study in Yucatán minipigs. Graefe's Archive For Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. PMID 27335025 DOI: 10.1007/S00417-016-3386-Y  0.318
2016 Brant Fernandes RA, Koss MJ, Falabella P, Stefanini FR, Maia M, Diniz B, Ribeiro R, Hu Y, Hinton D, Clegg DO, Chader G, Humayun MS. An Innovative Surgical Technique for Subretinal Transplantation of Human Embryonic Stem Cell-Derived Retinal Pigmented Epithelium in Yucatan Mini Pigs: Preliminary Results. Ophthalmic Surgery, Lasers & Imaging Retina. 47: 342-351. PMID 27065374 DOI: 10.3928/23258160-20160324-07  0.324
2016 Sreekumar PG, Ishikawa K, Spee C, Mehta HH, Wan J, Yen K, Cohen P, Kannan R, Hinton DR. The Mitochondrial-Derived Peptide Humanin Protects RPE Cells From Oxidative Stress, Senescence, and Mitochondrial Dysfunction. Investigative Ophthalmology & Visual Science. 57: 1238-1253. PMID 26990160 DOI: 10.1167/Iovs.15-17053  0.328
2016 Ishikawa K, Sreekumar PG, Spee C, Nazari H, Zhu D, Kannan R, Hinton DR. αB-Crystallin Regulates Subretinal Fibrosis by Modulation of Epithelial-Mesenchymal Transition. The American Journal of Pathology. PMID 26878210 DOI: 10.1016/J.Ajpath.2015.11.014  0.387
2016 Lopez P, Aguilar T, Wu R, Krishnan A, Kong D, Patel J, Javier H, Dang W, Wong D, Zhu D, Dodd J, Shad Y, Humayun M, Hinton D, Clegg D, et al. 445. cGMP Compliant Production for Human Embryonic Stem Cell Derived Retinal Pigment Epithelial Cells on a Synthetic Substrate for the Treatment of Non-Neovascular Age-Related Macular Degeneration for Phase I Clinical Study Molecular Therapy. 24: S176. DOI: 10.1016/S1525-0016(16)33254-3  0.338
2015 Ishikawa K, He S, Terasaki H, Nazari H, Zhang H, Spee C, Kannan R, Hinton DR. Resveratrol inhibits epithelial-mesenchymal transition of retinal pigment epithelium and development of proliferative vitreoretinopathy. Scientific Reports. 5: 16386. PMID 26552368 DOI: 10.1038/Srep16386  0.386
2015 Zhang H, He S, Spee C, Ishikawa K, Hinton DR. SIRT1 mediated inhibition of VEGF/VEGFR2 signaling by Resveratrol and its relevance to choroidal neovascularization. Cytokine. 76: 549-52. PMID 26174951 DOI: 10.1016/J.Cyto.2015.06.019  0.352
2015 Butchi N, Kapil P, Puntambekar S, Stohlman SA, Hinton DR, Bergmann CC. Myd88 Initiates Early Innate Immune Responses and Promotes CD4 T Cells during Coronavirus Encephalomyelitis. Journal of Virology. 89: 9299-312. PMID 26136579 DOI: 10.1128/Jvi.01199-15  0.323
2015 Nazari H, Zhang L, Zhu D, Chader GJ, Falabella P, Stefanini F, Rawland T, Clegg DO, Kashani AH, Hinton DR, Humayun MS. Stem cell based therapies for age-related macular degeneration: the promises and the challenges. Progress in Retinal and Eye Research. PMID 26113213 DOI: 10.1016/J.Preteyeres.2015.06.004  0.351
2015 Kannan R, Sreekumar PG, Hinton DR. Alpha crystallins in the retinal pigment epithelium and implications for the pathogenesis and treatment of age-related macular degeneration. Biochimica Et Biophysica Acta. PMID 26026469 DOI: 10.1016/J.Bbagen.2015.05.016  0.316
2015 Chan N, He S, Spee CK, Ishikawa K, Hinton DR. Attenuation of choroidal neovascularization by histone deacetylase inhibitor. Plos One. 10: e0120587. PMID 25807249 DOI: 10.1371/Journal.Pone.0120587  0.38
2015 Ishikawa K, Kannan R, Hinton DR. Molecular mechanisms of subretinal fibrosis in age-related macular degeneration. Experimental Eye Research. PMID 25773985 DOI: 10.1016/J.Exer.2015.03.009  0.326
2015 Hsiung J, Zhu D, Hinton DR. Polarized human embryonic stem cell-derived retinal pigment epithelial cell monolayers have higher resistance to oxidative stress-induced cell death than nonpolarized cultures. Stem Cells Translational Medicine. 4: 10-20. PMID 25411476 DOI: 10.5966/Sctm.2014-0205  0.371
2014 Kannan R, Hinton DR. Sodium iodate induced retinal degeneration: new insights from an old model. Neural Regeneration Research. 9: 2044-5. PMID 25657718 DOI: 10.4103/1673-5374.147927  0.313
2014 Hirano Y, Yasuma T, Mizutani T, Fowler BJ, Tarallo V, Yasuma R, Kim Y, Bastos-Carvalho A, Kerur N, Gelfand BD, Bogdanovich S, He S, Zhang X, Nozaki M, Ijima R, ... ... Hinton DR, et al. IL-18 is not therapeutic for neovascular age-related macular degeneration. Nature Medicine. 20: 1372-5. PMID 25473914 DOI: 10.1038/Nm.3671  0.319
2014 Fowler BJ, Gelfand BD, Kim Y, Kerur N, Tarallo V, Hirano Y, Amarnath S, Fowler DH, Radwan M, Young MT, Pittman K, Kubes P, Agarwal HK, Parang K, Hinton DR, et al. Nucleoside reverse transcriptase inhibitors possess intrinsic anti-inflammatory activity. Science (New York, N.Y.). 346: 1000-3. PMID 25414314 DOI: 10.1126/Science.1261754  0.316
2014 Sur A, Kesaraju S, Prentice H, Ayyanathan K, Baronas-Lowell D, Zhu D, Hinton DR, Blanks J, Weissbach H. Pharmacological protection of retinal pigmented epithelial cells by sulindac involves PPAR-α. Proceedings of the National Academy of Sciences of the United States of America. 111: 16754-9. PMID 25385631 DOI: 10.1073/Pnas.1419576111  0.379
2014 Kim Y, Tarallo V, Kerur N, Yasuma T, Gelfand BD, Bastos-Carvalho A, Hirano Y, Yasuma R, Mizutani T, Fowler BJ, Li S, Kaneko H, Bogdanovich S, Ambati BK, Hinton DR, et al. DICER1/Alu RNA dysmetabolism induces Caspase-8-mediated cell death in age-related macular degeneration. Proceedings of the National Academy of Sciences of the United States of America. 111: 16082-7. PMID 25349431 DOI: 10.1073/Pnas.1403814111  0.343
2014 Zhou P, Kannan R, Spee C, Sreekumar PG, Dou G, Hinton DR. Protection of retina by αB crystallin in sodium iodate induced retinal degeneration. Plos One. 9: e98275. PMID 24874187 DOI: 10.1371/Journal.Pone.0098275  0.389
2014 Wang W, Sreekumar PG, Valluripalli V, Shi P, Wang J, Lin YA, Cui H, Kannan R, Hinton DR, MacKay JA. Protein polymer nanoparticles engineered as chaperones protect against apoptosis in human retinal pigment epithelial cells. Journal of Controlled Release : Official Journal of the Controlled Release Society. 191: 4-14. PMID 24780268 DOI: 10.1016/J.Jconrel.2014.04.028  0.599
2014 Sonoda S, Nagineni CN, Kitamura M, Spee C, Kannan R, Hinton DR. Ceramide inhibits connective tissue growth factor expression by human retinal pigment epithelial cells. Cytokine. 68: 137-40. PMID 24758915 DOI: 10.1016/J.Cyto.2014.03.011  0.396
2014 Kapil P, Stohlman SA, Hinton DR, Bergmann CC. PKR mediated regulation of inflammation and IL-10 during viral encephalomyelitis. Journal of Neuroimmunology. 270: 1-12. PMID 24642385 DOI: 10.1016/J.Jneuroim.2014.02.012  0.319
2014 Butchi NB, Hinton DR, Stohlman SA, Kapil P, Fensterl V, Sen GC, Bergmann CC. Ifit2 deficiency results in uncontrolled neurotropic coronavirus replication and enhanced encephalitis via impaired alpha/beta interferon induction in macrophages. Journal of Virology. 88: 1051-64. PMID 24198415 DOI: 10.1128/Jvi.02272-13  0.308
2013 Savarin C, Bergmann CC, Hinton DR, Stohlman SA. MMP-independent role of TIMP-1 at the blood brain barrier during viral encephalomyelitis. Asn Neuro. 5: e00127. PMID 24156369 DOI: 10.1042/An20130033  0.34
2013 Ribeiro RM, Oregon A, Diniz B, Fernandes RB, Koss MJ, Charafeddin W, Hu Y, Thomas P, Thomas BB, Maia M, Chader GJ, Hinton DR, Humayun MS. In vivo detection of hESC-RPE cells via confocal near-infrared fundus reflectance. Ophthalmic Surgery, Lasers & Imaging Retina. 44: 380-4. PMID 23883533 DOI: 10.3928/23258160-20130715-09  0.322
2013 Diniz B, Thomas P, Thomas B, Ribeiro R, Hu Y, Brant R, Ahuja A, Zhu D, Liu L, Koss M, Maia M, Chader G, Hinton DR, Humayun MS. Subretinal implantation of retinal pigment epithelial cells derived from human embryonic stem cells: improved survival when implanted as a monolayer. Investigative Ophthalmology & Visual Science. 54: 5087-96. PMID 23833067 DOI: 10.1167/Iovs.12-11239  0.321
2013 Phares TW, Stohlman SA, Hinton DR, Bergmann CC. Astrocyte-derived CXCL10 drives accumulation of antibody-secreting cells in the central nervous system during viral encephalomyelitis. Journal of Virology. 87: 3382-92. PMID 23302888 DOI: 10.1128/Jvi.03307-12  0.354
2012 Sohn EH, He S, Kim LA, Salehi-Had H, Javaheri M, Spee C, Dustin L, Hinton DR, Eliott D. Angiofibrotic response to vascular endothelial growth factor inhibition in diabetic retinal detachment: report no. 1. Archives of Ophthalmology (Chicago, Ill. : 1960). 130: 1127-34. PMID 22965588 DOI: 10.1001/Archophthalmol.2012.1611  0.326
2012 Gundimeda U, McNeill TH, Elhiani AA, Schiffman JE, Hinton DR, Gopalakrishna R. Green tea polyphenols precondition against cell death induced by oxygen-glucose deprivation via stimulation of laminin receptor, generation of reactive oxygen species, and activation of protein kinase Cε. The Journal of Biological Chemistry. 287: 34694-708. PMID 22879598 DOI: 10.1074/Jbc.M112.356899  0.336
2012 Dridi S, Hirano Y, Tarallo V, Kim Y, Fowler BJ, Ambati BK, Bogdanovich S, Chiodo VA, Hauswirth WW, Kugel JF, Goodrich JA, Ponicsan SL, Hinton DR, Kleinman ME, Baffi JZ, et al. ERK1/2 activation is a therapeutic target in age-related macular degeneration. Proceedings of the National Academy of Sciences of the United States of America. 109: 13781-6. PMID 22869729 DOI: 10.1073/Pnas.1206494109  0.324
2012 Hu Y, Liu L, Lu B, Zhu D, Ribeiro R, Diniz B, Thomas PB, Ahuja AK, Hinton DR, Tai YC, Hikita ST, Johnson LV, Clegg DO, Thomas BB, Humayun MS. A novel approach for subretinal implantation of ultrathin substrates containing stem cell-derived retinal pigment epithelium monolayer. Ophthalmic Research. 48: 186-91. PMID 22868580 DOI: 10.1159/000338749  0.301
2012 Dou G, Sreekumar PG, Spee C, He S, Ryan SJ, Kannan R, Hinton DR. Deficiency of αB crystallin augments ER stress-induced apoptosis by enhancing mitochondrial dysfunction. Free Radical Biology & Medicine. 53: 1111-22. PMID 22781655 DOI: 10.1016/J.Freeradbiomed.2012.06.042  0.315
2012 Kannan R, Sreekumar PG, Hinton DR. Novel roles for α-crystallins in retinal function and disease. Progress in Retinal and Eye Research. 31: 576-604. PMID 22721717 DOI: 10.1016/J.Preteyeres.2012.06.001  0.369
2012 Sreekumar PG, Spee C, Ryan SJ, Cole SP, Kannan R, Hinton DR. Mechanism of RPE cell death in α-crystallin deficient mice: a novel and critical role for MRP1-mediated GSH efflux. Plos One. 7: e33420. PMID 22442691 DOI: 10.1371/Journal.Pone.0033420  0.377
2012 Xu J, Zhu D, Sonoda S, He S, Spee C, Ryan SJ, Hinton DR. Over-expression of BMP4 inhibits experimental choroidal neovascularization by modulating VEGF and MMP-9. Angiogenesis. 15: 213-27. PMID 22392094 DOI: 10.1007/S10456-012-9254-4  0.446
2012 Lu B, Zhu D, Hinton D, Humayun MS, Tai YC. Mesh-supported submicron parylene-C membranes for culturing retinal pigment epithelial cells. Biomedical Microdevices. 14: 659-67. PMID 22391881 DOI: 10.1007/S10544-012-9645-8  0.312
2011 Amin EM, Oltean S, Hua J, Gammons MV, Hamdollah-Zadeh M, Welsh GI, Cheung MK, Ni L, Kase S, Rennel ES, Symonds KE, Nowak DG, Royer-Pokora B, Saleem MA, Hagiwara M, ... ... Hinton DR, et al. WT1 mutants reveal SRPK1 to be a downstream angiogenesis target by altering VEGF splicing. Cancer Cell. 20: 768-80. PMID 22172722 DOI: 10.1016/J.Ccr.2011.10.016  0.313
2011 Kannan R, Sreekumar PG, Hinton DR. VEGF and PEDF secretion in ARPE-19 and fhRPE cells. Investigative Ophthalmology & Visual Science. 52: 9047. PMID 22104197 DOI: 10.1167/Iovs.11-8737  0.348
2011 Sreekumar PG, Hinton DR, Kannan R. Methionine sulfoxide reductase A: Structure, function and role in ocular pathology. World Journal of Biological Chemistry. 2: 184-92. PMID 21909460 DOI: 10.4331/Wjbc.V2.I8.184  0.385
2011 Khankan R, Oliver N, He S, Ryan SJ, Hinton DR. Regulation of fibronectin-EDA through CTGF domain-specific interactions with TGFβ2 and its receptor TGFβRII. Investigative Ophthalmology & Visual Science. 52: 5068-78. PMID 21571675 DOI: 10.1167/Iovs.11-7191  0.777
2011 Marques CP, Kapil P, Hinton DR, Hindinger C, Nutt SL, Ransohoff RM, Phares TW, Stohlman SA, Bergmann CC. CXCR3-dependent plasma blast migration to the central nervous system during viral encephalomyelitis. Journal of Virology. 85: 6136-47. PMID 21507985 DOI: 10.1128/Jvi.00202-11  0.342
2011 Xu J, Zhu D, He S, Spee C, Ryan SJ, Hinton DR. Transcriptional regulation of bone morphogenetic protein 4 by tumor necrosis factor and its relationship with age-related macular degeneration. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2221-33. PMID 21411747 DOI: 10.1096/Fj.10-178350  0.458
2011 Sadler TR, Nguyen PT, Yang J, Givrad TK, Mayer EA, Maarek JM, Hinton DR, Holschneider DP. Antenatal maternal stress alters functional brain responses in adult offspring during conditioned fear. Brain Research. 1385: 163-74. PMID 21300034 DOI: 10.1016/J.Brainres.2011.01.104  0.671
2011 Chothe PP, Gnana-Prakasam JP, Ananth S, Martin PM, Kannan R, Hinton DR, Smith SB, Ganapathy V. Transport of hepcidin, an iron-regulatory peptide hormone, into retinal pigment epithelial cells via oligopeptide transporters and its relevance to iron homeostasis. Biochemical and Biophysical Research Communications. 405: 244-9. PMID 21219868 DOI: 10.1016/J.Bbrc.2011.01.018  0.311
2011 Phares TW, Marques CP, Stohlman SA, Hinton DR, Bergmann CC. Factors supporting intrathecal humoral responses following viral encephalomyelitis. Journal of Virology. 85: 2589-98. PMID 21191015 DOI: 10.1128/Jvi.02260-10  0.364
2011 Zhu D, Deng X, Spee C, Sonoda S, Hsieh CL, Barron E, Pera M, Hinton DR. Polarized secretion of PEDF from human embryonic stem cell-derived RPE promotes retinal progenitor cell survival. Investigative Ophthalmology & Visual Science. 52: 1573-85. PMID 21087957 DOI: 10.1167/Iovs.10-6413  0.322
2010 Sreekumar PG, Kannan R, Kitamura M, Spee C, Barron E, Ryan SJ, Hinton DR. αB crystallin is apically secreted within exosomes by polarized human retinal pigment epithelium and provides neuroprotection to adjacent cells. Plos One. 5: e12578. PMID 20949024 DOI: 10.1371/Journal.Pone.0012578  0.395
2010 Gundimeda U, McNeill TH, Schiffman JE, Hinton DR, Gopalakrishna R. Green tea polyphenols potentiate the action of nerve growth factor to induce neuritogenesis: possible role of reactive oxygen species. Journal of Neuroscience Research. 88: 3644-55. PMID 20936703 DOI: 10.1002/Jnr.22519  0.326
2010 Phares TW, Stohlman SA, Hinton DR, Atkinson R, Bergmann CC. Enhanced antiviral T cell function in the absence of B7-H1 is insufficient to prevent persistence but exacerbates axonal bystander damage during viral encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 185: 5607-18. PMID 20876353 DOI: 10.4049/Jimmunol.1001984  0.328
2010 Zhou J, He S, Zhang N, Spee C, Zhou P, Ryan SJ, Kannan R, Hinton DR. Neutrophils compromise retinal pigment epithelial barrier integrity. Journal of Biomedicine & Biotechnology. 2010: 289360. PMID 20204129 DOI: 10.1155/2010/289360  0.707
2010 Kase S, He S, Sonoda S, Kitamura M, Spee C, Wawrousek E, Ryan SJ, Kannan R, Hinton DR. alphaB-crystallin regulation of angiogenesis by modulation of VEGF. Blood. 115: 3398-406. PMID 20023214 DOI: 10.1182/Blood-2009-01-197095  0.376
2010 Wang M, Ye R, Barron E, Baumeister P, Mao C, Luo S, Fu Y, Luo B, Dubeau L, Hinton DR, Lee AS. Essential role of the unfolded protein response regulator GRP78/BiP in protection from neuronal apoptosis. Cell Death and Differentiation. 17: 488-98. PMID 19816510 DOI: 10.1038/Cdd.2009.144  0.317
2010 Zhu D, Sreekumar PG, Hinton DR, Kannan R. Expression and regulation of enzymes in the ceramide metabolic pathway in human retinal pigment epithelial cells and their relevance to retinal degeneration. Vision Research. 50: 643-51. PMID 19765607 DOI: 10.1016/J.Visres.2009.09.002  0.402
2010 He S, Kumar SR, Zhou P, Krasnoperov V, Ryan SJ, Gill PS, Hinton DR. Soluble EphB4 inhibition of PDGF-induced RPE migration in vitro. Investigative Ophthalmology & Visual Science. 51: 543-52. PMID 19696168 DOI: 10.1167/Iovs.09-3475  0.374
2009 Zhu D, Deng X, Xu J, Hinton DR. What determines the switch between atrophic and neovascular forms of age related macular degeneration? - the role of BMP4 induced senescence. Aging. 1: 740-5. PMID 20157553  0.358
2009 Ireland DD, Stohlman SA, Hinton DR, Kapil P, Silverman RH, Atkinson RA, Bergmann CC. RNase L mediated protection from virus induced demyelination. Plos Pathogens. 5: e1000602. PMID 19798426 DOI: 10.1371/Journal.Ppat.1000602  0.318
2009 Sadler TR, Khodavirdi AC, Hinton DR, Holschneider DP. Snap-frozen brain tissue sections stored with desiccant at ambient laboratory conditions without chemical fixation are resistant to degradation for a minimum of 6 months. Applied Immunohistochemistry & Molecular Morphology : Aimm / Official Publication of the Society For Applied Immunohistochemistry. 17: 165-71. PMID 19521279 DOI: 10.1097/Pai.0B013E3181853001  0.675
2009 Sonoda S, Spee C, Barron E, Ryan SJ, Kannan R, Hinton DR. A protocol for the culture and differentiation of highly polarized human retinal pigment epithelial cells. Nature Protocols. 4: 662-73. PMID 19373231 DOI: 10.1038/Nprot.2009.33  0.327
2009 Kim YH, He S, Kase S, Kitamura M, Ryan SJ, Hinton DR. Regulated secretion of complement factor H by RPE and its role in RPE migration. Graefe's Archive For Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fã¼R Klinische Und Experimentelle Ophthalmologie. 247: 651-9. PMID 19214553 DOI: 10.1007/S00417-009-1049-Y  0.343
2009 Zhu D, Wu J, Spee C, Ryan SJ, Hinton DR. BMP4 mediates oxidative stress-induced retinal pigment epithelial cell senescence and is overexpressed in age-related macular degeneration. The Journal of Biological Chemistry. 284: 9529-39. PMID 19158083 DOI: 10.1074/Jbc.M809393200  0.432
2009 Sreekumar PG, Ding Y, Ryan SJ, Kannan R, Hinton DR. Regulation of thioredoxin by ceramide in retinal pigment epithelial cells. Experimental Eye Research. 88: 410-7. PMID 18996115 DOI: 10.1016/J.Exer.2008.10.009  0.419
2008 Yang Z, Stratton C, Francis PJ, Kleinman ME, Tan PL, Gibbs D, Tong Z, Chen H, Constantine R, Yang X, Chen Y, Zeng J, Davey L, Ma X, Hau VS, ... ... Hinton DR, et al. Toll-like receptor 3 and geographic atrophy in age-related macular degeneration. The New England Journal of Medicine. 359: 1456-63. PMID 18753640 DOI: 10.1056/Nejmoa0802437  0.342
2008 Li J, Ni M, Lee B, Barron E, Hinton DR, Lee AS. The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells. Cell Death and Differentiation. 15: 1460-71. PMID 18551133 DOI: 10.1038/Cdd.2008.81  0.328
2008 He S, Chen Y, Khankan R, Barron E, Burton R, Zhu D, Ryan SJ, Oliver N, Hinton DR. Connective tissue growth factor as a mediator of intraocular fibrosis. Investigative Ophthalmology & Visual Science. 49: 4078-88. PMID 18450591 DOI: 10.1167/Iovs.07-1302  0.795
2008 Sreekumar PG, Zhou J, Sohn J, Spee C, Ryan SJ, Maurer BJ, Kannan R, Hinton DR. N-(4-hydroxyphenyl) retinamide augments laser-induced choroidal neovascularization in mice. Investigative Ophthalmology & Visual Science. 49: 1210-20. PMID 18326751 DOI: 10.1167/Iovs.07-0667  0.716
2008 He S, Yaung J, Kim YH, Barron E, Ryan SJ, Hinton DR. Endoplasmic reticulum stress induced by oxidative stress in retinal pigment epithelial cells. Graefe's Archive For Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fã¼R Klinische Und Experimentelle Ophthalmologie. 246: 677-83. PMID 18278507 DOI: 10.1007/S00417-008-0770-2  0.74
2008 Yaung J, Kannan R, Wawrousek EF, Spee C, Sreekumar PG, Hinton DR. Exacerbation of retinal degeneration in the absence of alpha crystallins in an in vivo model of chemically induced hypoxia. Experimental Eye Research. 86: 355-65. PMID 18191123 DOI: 10.1016/J.Exer.2007.11.007  0.731
2008 Ireland DD, Stohlman SA, Hinton DR, Atkinson R, Bergmann CC. Type I interferons are essential in controlling neurotropic coronavirus infection irrespective of functional CD8 T cells. Journal of Virology. 82: 300-10. PMID 17928334 DOI: 10.1128/Jvi.01794-07  0.332
2007 Yaung J, Jin M, Barron E, Spee C, Wawrousek EF, Kannan R, Hinton DR. alpha-Crystallin distribution in retinal pigment epithelium and effect of gene knockouts on sensitivity to oxidative stress. Molecular Vision. 13: 566-77. PMID 17438522  0.737
2007 Agrawal RN, He S, Spee C, Cui JZ, Ryan SJ, Hinton DR. In vivo models of proliferative vitreoretinopathy. Nature Protocols. 2: 67-77. PMID 17401340 DOI: 10.1038/Nprot.2007.4  0.34
2006 He S, Incardona F, Jin M, Ryan SJ, Hinton DR. Thrombospondin-1 expression in RPE and choroidal neovascular membranes. Yan Ke Xue Bao = Eye Science / "Yan Ke Xue Bao" Bian Ji Bu. 22: 265-74. PMID 17378161  0.482
2006 Hindinger C, Hinton DR, Kirwin SJ, Atkinson RD, Burnett ME, Bergmann CC, Stohlman SA. Liver X receptor activation decreases the severity of experimental autoimmune encephalomyelitis. Journal of Neuroscience Research. 84: 1225-34. PMID 16955483 DOI: 10.1002/Jnr.21038  0.328
2006 Kirwin SJ, Dowdell KC, Hindinger C, Feng N, Bergmann CC, Hinton DR, Stohlman SA. Altered neuroantigen-specific cytokine secretion in a Th2 environment reduces experimental autoimmune encephalomyelitis. Journal of Neuroimmunology. 178: 30-9. PMID 16814872 DOI: 10.1016/J.Jneuroim.2006.05.015  0.318
2006 Sreekumar PG, Kannan R, de Silva AT, Burton R, Ryan SJ, Hinton DR. Thiol regulation of vascular endothelial growth factor-A and its receptors in human retinal pigment epithelial cells. Biochemical and Biophysical Research Communications. 346: 1200-6. PMID 16793007 DOI: 10.1016/J.Bbrc.2006.06.021  0.39
2006 Lutty GA, Chan-Ling T, Phelps DL, Adamis AP, Berns KI, Chan CK, Cole CH, D'Amore PA, Das A, Deng WT, Dobson V, Flynn JT, Friedlander M, Fulton A, Good WV, ... ... Hinton DR, et al. Proceedings of the Third International Symposium on Retinopathy of Prematurity: an update on ROP from the lab to the nursery (November 2003, Anaheim, California). Molecular Vision. 12: 532-80. PMID 16735995  0.52
2006 Kramerov AA, Saghizadeh M, Pan H, Kabosova A, Montenarh M, Ahmed K, Penn JS, Chan CK, Hinton DR, Grant MB, Ljubimov AV. Expression of protein kinase CK2 in astroglial cells of normal and neovascularized retina. The American Journal of Pathology. 168: 1722-36. PMID 16651637 DOI: 10.2353/Ajpath.2006.050533  0.616
2006 Hoffmann S, He S, Ehren M, Ryan SJ, Wiedemann P, Hinton DR. MMP-2 and MMP-9 secretion by rpe is stimulated by angiogenic molecules found in choroidal neovascular membranes. Retina (Philadelphia, Pa.). 26: 454-61. PMID 16603966 DOI: 10.1097/01.Iae.0000238549.74626.33  0.316
2006 Gamulescu MA, Chen Y, He S, Spee C, Jin M, Ryan SJ, Hinton DR. Transforming growth factor beta2-induced myofibroblastic differentiation of human retinal pigment epithelial cells: regulation by extracellular matrix proteins and hepatocyte growth factor. Experimental Eye Research. 83: 212-22. PMID 16563380 DOI: 10.1016/J.Exer.2005.12.007  0.55
2006 Zuo J, Stohlman SA, Hoskin JB, Hinton DR, Atkinson R, Bergmann CC. Mouse hepatitis virus pathogenesis in the central nervous system is independent of IL-15 and natural killer cells. Virology. 350: 206-15. PMID 16510164 DOI: 10.1016/J.Virol.2006.01.027  0.33
2006 González JM, Bergmann CC, Ramakrishna C, Hinton DR, Atkinson R, Hoskin J, Macklin WB, Stohlman SA. Inhibition of interferon-gamma signaling in oligodendroglia delays coronavirus clearance without altering demyelination. The American Journal of Pathology. 168: 796-804. PMID 16507895 DOI: 10.2353/Ajpath.2006.050496  0.319
2006 Hangai M, He S, Hoffmann S, Lim JI, Ryan SJ, Hinton DR. Sequential induction of angiogenic growth factors by TNF-alpha in choroidal endothelial cells. Journal of Neuroimmunology. 171: 45-56. PMID 16288810 DOI: 10.1016/J.Jneuroim.2005.09.018  0.346
2005 Lim JI, Spee C, Hangai M, Rocha J, Ying HS, Ryan SJ, Hinton DR. Neuropilin-1 expression by endothelial cells and retinal pigment epithelial cells in choroidal neovascular membranes. American Journal of Ophthalmology. 140: 1044-1050. PMID 16376649 DOI: 10.1016/J.Ajo.2005.07.021  0.362
2005 He S, Ding Y, Zhou J, Krasnoperov V, Zozulya S, Kumar SR, Ryan SJ, Gill PS, Hinton DR. Soluble EphB4 regulates choroidal endothelial cell function and inhibits laser-induced choroidal neovascularization. Investigative Ophthalmology & Visual Science. 46: 4772-9. PMID 16303978 DOI: 10.1167/Iovs.05-0502  0.703
2005 Jin M, Yaung J, Kannan R, He S, Ryan SJ, Hinton DR. Hepatocyte growth factor protects RPE cells from apoptosis induced by glutathione depletion. Investigative Ophthalmology & Visual Science. 46: 4311-9. PMID 16249513 DOI: 10.1167/Iovs.05-0353  0.763
2005 Pan J, Al-Dubaib M, Liao CP, Fujino Y, Hinton DR, Hayes KA, Mathes LE, Roy-Burman P. In vivo expression of GFP transgene delivered via a replicating feline leukemia virus. Veterinary Microbiology. 110: 181-95. PMID 16143471 DOI: 10.1016/J.Vetmic.2005.07.015  0.343
2005 Hindinger C, Gonzalez JM, Bergmann CC, Fuss B, Hinton DR, Atkinson RD, Macklin WB, Stohlman SA. Astrocyte expression of a dominant-negative interferon-gamma receptor. Journal of Neuroscience Research. 82: 20-31. PMID 16118798 DOI: 10.1002/Jnr.20616  0.301
2005 Sreekumar PG, Kannan R, Yaung J, Spee CK, Ryan SJ, Hinton DR. Protection from oxidative stress by methionine sulfoxide reductases in RPE cells. Biochemical and Biophysical Research Communications. 334: 245-53. PMID 15993845 DOI: 10.1016/J.Bbrc.2005.06.081  0.726
2005 Zhou J, Pham L, Zhang N, He S, Gamulescu MA, Spee C, Ryan SJ, Hinton DR. Neutrophils promote experimental choroidal neovascularization. Molecular Vision. 11: 414-24. PMID 15988410  0.675
2005 Hoffmann S, He S, Jin M, Ehren M, Wiedemann P, Ryan SJ, Hinton DR. A selective cyclic integrin antagonist blocks the integrin receptors alphavbeta3 and alphavbeta5 and inhibits retinal pigment epithelium cell attachment, migration and invasion. Bmc Ophthalmology. 5: 16. PMID 15987521 DOI: 10.1186/1471-2415-5-16  0.543
2005 Chan CK, Pham LN, Zhou J, Spee C, Ryan SJ, Hinton DR. Differential expression of pro- and antiangiogenic factors in mouse strain-dependent hypoxia-induced retinal neovascularization. Laboratory Investigation; a Journal of Technical Methods and Pathology. 85: 721-33. PMID 15856049 DOI: 10.1038/Labinvest.3700277  0.748
2005 Zhou J, Hinton DR, Stohlman SA, Liu CP, Zhong L, Marten NW. Maintenance of CD8+ T cells during acute viral infection of the central nervous system requires CD4+ T cells but not interleukin-2. Viral Immunology. 18: 162-9. PMID 15802960 DOI: 10.1089/Vim.2005.18.162  0.67
2005 Zhou J, Marten NW, Bergmann CC, Macklin WB, Hinton DR, Stohlman SA. Expression of matrix metalloproteinases and their tissue inhibitor during viral encephalitis. Journal of Virology. 79: 4764-73. PMID 15795262 DOI: 10.1128/Jvi.79.8.4764-4773.2005  0.696
2005 González JM, Bergmann CC, Fuss B, Hinton DR, Kangas C, Macklin WB, Stohlman SA. Expression of a dominant negative IFN-gammareceptor on mouse oligodendrocytes. Glia. 51: 22-34. PMID 15779088 DOI: 10.1002/Glia.20182  0.304
2005 Sreekumar PG, Kannan R, Yaung J, Spee CK, Ryan SJ, Hinton DR. Erratum to “Protection from oxidative stress by methionine sulfoxide reductases in RPE cells” [Biochem. Biophys. Res. Commun. 334 (2005) 245–253] Biochemical and Biophysical Research Communications. 337: 1353. DOI: 10.1016/J.Bbrc.2005.09.153  0.675
2004 Kannan R, Jin M, Gamulescu MA, Hinton DR. Ceramide-induced apoptosis: role of catalase and hepatocyte growth factor. Free Radical Biology & Medicine. 37: 166-75. PMID 15203188 DOI: 10.1016/J.Freeradbiomed.2004.04.011  0.531
2004 Weiner LP, Louie KA, Atalla LR, Kochounian HH, Du J, Wei W, Hinton DR, Gordon EM, Anderson WF, McMillan M. Gene therapy in a murine model for clinical application to multiple sclerosis. Annals of Neurology. 55: 390-9. PMID 14991817 DOI: 10.1002/Ana.10858  0.307
2004 Bergmann CC, Parra B, Hinton DR, Ramakrishna C, Dowdell KC, Stohlman SA. Perforin and gamma interferon-mediated control of coronavirus central nervous system infection by CD8 T cells in the absence of CD4 T cells. Journal of Virology. 78: 1739-50. PMID 14747539 DOI: 10.1128/Jvi.78.4.1739-1750.2004  0.316
2004 Chan CK, Pham LN, Chinn C, Spee C, Ryan SJ, Akhurst RJ, Hinton DR. Mouse strain-dependent heterogeneity of resting limbal vasculature. Investigative Ophthalmology & Visual Science. 45: 441-7. PMID 14744883 DOI: 10.1167/Iovs.03-0869  0.574
2004 Jin M, Chen Y, He S, Ryan SJ, Hinton DR. Hepatocyte growth factor and its role in the pathogenesis of retinal detachment. Investigative Ophthalmology & Visual Science. 45: 323-9. PMID 14691191 DOI: 10.1167/Iovs.03-0355  0.547
2003 Karanjawala ZE, Hinton DR, Oh E, Hsieh CL, Lieber MR. Developmental retinal apoptosis in Ku86-/- mice. Dna Repair. 2: 1429-34. PMID 14642570 DOI: 10.1016/J.Dnarep.2003.08.011  0.346
2003 He S, Jin ML, Worpel V, Hinton DR. A role for connective tissue growth factor in the pathogenesis of choroidal neovascularization. Archives of Ophthalmology (Chicago, Ill. : 1960). 121: 1283-8. PMID 12963611 DOI: 10.1001/Archopht.121.9.1283  0.554
2003 Wu LY, Li M, Hinton DR, Guo L, Jiang S, Wang JT, Zeng A, Xie JB, Snead M, Shuler C, Maxson RE, Liu YH. Microphthalmia resulting from MSX2-induced apoptosis in the optic vesicle. Investigative Ophthalmology & Visual Science. 44: 2404-12. PMID 12766037 DOI: 10.1167/Iovs.02-0317  0.304
2003 Zhou J, Stohlman SA, Hinton DR, Marten NW. Neutrophils promote mononuclear cell infiltration during viral-induced encephalitis. Journal of Immunology (Baltimore, Md. : 1950). 170: 3331-6. PMID 12626593 DOI: 10.4049/Jimmunol.170.6.3331  0.677
2003 Bergmann CC, Parra B, Hinton DR, Chandran R, Morrison M, Stohlman SA. Perforin-mediated effector function within the central nervous system requires IFN-gamma-mediated MHC up-regulation. Journal of Immunology (Baltimore, Md. : 1950). 170: 3204-13. PMID 12626579 DOI: 10.4049/Jimmunol.170.6.3204  0.318
2002 Stohlman SA, Ramakrishna C, Tschen SI, Hinton DR, Bergmann CC. The art of survival during viral persistence. Journal of Neurovirology. 8: 53-8. PMID 12491152 DOI: 10.1080/13550280290167884  0.318
2002 Simard M, Zhang W, Hinton DR, Chen TC, Weiss MH, Su YZ, Gopalakrishna R, Law RE, Couldwell WT. Tamoxifen-induced growth arrest and apoptosis in pituitary tumor cells in vitro via a protein kinase C-independent pathway. Cancer Letters. 185: 131-8. PMID 12169386 DOI: 10.1016/S0304-3835(02)00261-6  0.34
2002 Jin M, Barron E, He S, Ryan SJ, Hinton DR. Regulation of RPE intercellular junction integrity and function by hepatocyte growth factor. Investigative Ophthalmology & Visual Science. 43: 2782-90. PMID 12147616  0.474
2002 Hinton DR, He S, Jin ML, Barron E, Ryan SJ. Novel growth factors involved in the pathogenesis of proliferative vitreoretinopathy. Eye (London, England). 16: 422-8. PMID 12101449 DOI: 10.1038/Sj.Eye.6700190  0.548
2002 Zhou J, Stohlman SA, Atkinson R, Hinton DR, Marten NW. Matrix metalloproteinase expression correlates with virulence following neurotropic mouse hepatitis virus infection. Journal of Virology. 76: 7374-84. PMID 12097550 DOI: 10.1128/Jvi.76.15.7374-7384.2002  0.687
2001 Zhou J, Stohlman SA, Marten NW, Hinton DR. Regulation of matrix metalloproteinase (MMP) and tissue inhibitor of matrix metalloproteinase (TIMP) genes during JHMV infection of the central nervous system. Advances in Experimental Medicine and Biology. 494: 329-34. PMID 11774488 DOI: 10.1007/978-1-4615-1325-4_49  0.68
2001 Masood R, Cai J, Zheng T, Smith DL, Hinton DR, Gill PS. Vascular endothelial growth factor (VEGF) is an autocrine growth factor for VEGF receptor-positive human tumors. Blood. 98: 1904-13. PMID 11535528 DOI: 10.1182/Blood.V98.6.1904  0.317
2001 Hangai M, Moon YS, Kitaya N, Chan CK, Wu DY, Peters KG, Ryan SJ, Hinton DR. Systemically expressed soluble Tie2 inhibits intraocular neovascularization. Human Gene Therapy. 12: 1311-21. PMID 11440624 DOI: 10.1089/104303401750270968  0.619
2001 Murata T, Hata Y, Ishibashi T, Kim S, Hsueh WA, Law RE, Hinton DR. Response of experimental retinal neovascularization to thiazolidinediones. Archives of Ophthalmology (Chicago, Ill. : 1960). 119: 709-17. PMID 11346398 DOI: 10.1001/Archopht.119.5.709  0.307
2001 Stohlman SA, Hinton DR. Viral induced demyelination. Brain Pathology (Zurich, Switzerland). 11: 92-106. PMID 11145206 DOI: 10.1111/J.1750-3639.2001.Tb00384.X  0.311
2000 Cai J, Zheng T, Masood R, Smith DL, Hinton DR, Kim CN, Fang G, Bhalla K, Gill PS. Paclitaxel Induces Apoptosis in AIDS-Related Kaposi's Sarcoma Cells. Sarcoma. 4: 37-45. PMID 18521433 DOI: 10.1155/S1357714X00000074  0.349
2000 Jin M, He S, Wörpel V, Ryan SJ, Hinton DR. Promotion of adhesion and migration of RPE cells to provisional extracellular matrices by TNF-alpha. Investigative Ophthalmology & Visual Science. 41: 4324-32. PMID 11095634  0.439
2000 Marten NW, Stohlman SA, Atkinson RD, Hinton DR, Fleming JO, Bergmann CC. Contributions of CD8+ T cells and viral spread to demyelinating disease. Journal of Immunology (Baltimore, Md. : 1950). 164: 4080-8. PMID 10754301 DOI: 10.4049/Jimmunol.164.8.4080  0.318
1999 Albuquerque FC, Weiss MH, Kovacs K, Horvath E, Sasano H, Hinton DR. A functioning composite 'corticotroph' pituitary adenoma with interspersed adrenocortical cells. Pituitary. 1: 279-84. PMID 11081209 DOI: 10.1023/A:1009962627216  0.303
1999 Zhao MW, Jin ML, He S, Spee C, Ryan SJ, Hinton DR. A distinct integrin-mediated phagocytic pathway for extracellular matrix remodeling by RPE cells. Investigative Ophthalmology & Visual Science. 40: 2713-23. PMID 10509670  0.438
1999 Kundu RK, Sangiorgi F, Wu LY, Pattengale PK, Hinton DR, Gill PS, Maxson R. Expression of the human immunodeficiency virus-Tat gene in lymphoid tissues of transgenic mice is associated with B-cell lymphoma. Blood. 94: 275-82. PMID 10381523 DOI: 10.1182/Blood.V94.1.275.413A30_275_282  0.342
1999 Hofman FM, Chen P, Incardona F, Zidovetzki R, Hinton DR. HIV-1 tat protein induces the production of interleukin-8 by human brain-derived endothelial cells. Journal of Neuroimmunology. 94: 28-39. PMID 10376933 DOI: 10.1016/S0165-5728(98)00198-2  0.31
1999 Casella AM, Taba KE, Kimura H, Spee C, Cardillo JA, Ryan SJ, Hinton DR. Retinal pigment epithelial cells are heterogeneous in their expression of MHC-II after stimulation with interferon-gamma. Experimental Eye Research. 68: 423-30. PMID 10192799 DOI: 10.1006/Exer.1998.0621  0.352
1998 Hoffmann S, Spee C, Murata T, Cui JZ, Ryan SJ, Hinton DR. Rapid isolation of choriocapillary endothelial cells by Lycopersicon esculentum-coated Dynabeads. Graefe's Archive For Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fã¼R Klinische Und Experimentelle Ophthalmologie. 236: 779-84. PMID 9801894 DOI: 10.1007/S004170050158  0.333
1998 Lin MT, Hinton DR, Stohlman SA. Mechanisms of viral clearance in perforin-deficient mice. Advances in Experimental Medicine and Biology. 440: 431-6. PMID 9782311 DOI: 10.1007/978-1-4615-5331-1_54  0.309
1998 He PM, He S, Garner JA, Ryan SJ, Hinton DR. Retinal pigment epithelial cells secrete and respond to hepatocyte growth factor. Biochemical and Biophysical Research Communications. 249: 253-7. PMID 9705867 DOI: 10.1006/Bbrc.1998.9087  0.384
1998 Hoffman S, Gopalakrishna R, Gundimeda U, Murata T, Spee C, Ryan SJ, Hinton DR. Verapamil inhibits proliferation, migration and protein kinase C activity in human retinal pigment epithelial cells. Experimental Eye Research. 67: 45-52. PMID 9702177 DOI: 10.1006/Exer.1998.0491  0.366
1998 Murata T, Hoffmann S, Ishibashi T, Spee C, Gordon EM, Anderson WF, Hinton DR, Ryan SJ. Retrovirus-mediated gene transfer targeted to retinal photocoagulation sites. Diabetologia. 41: 500-6. PMID 9628265 DOI: 10.1007/S001250050938  0.337
1998 Sakamoto T, Spee C, Scuric Z, Gordon EM, Hinton DR, Anderson WF, Ryan SJ. Ability of retroviral transduction to modify the angiogenic characteristics of RPE cells. Graefe's Archive For Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fã¼R Klinische Und Experimentelle Ophthalmologie. 236: 220-9. PMID 9541827 DOI: 10.1007/S004170050068  0.377
1998 Hinton DR, He S, Graf K, Yang D, Hsueh WA, Ryan SJ, Law RE. Mitogen-activated protein kinase activation mediates PDGF-directed migration of RPE cells. Experimental Cell Research. 239: 11-5. PMID 9511719 DOI: 10.1006/Excr.1997.3873  0.342
1998 Shimon I, Hinton DR, Weiss MH, Melmed S. Prolactinomas express human heparin-binding secretory transforming gene (hst) protein product: marker of tumour invasiveness. Clinical Endocrinology. 48: 23-9. PMID 9509064 DOI: 10.1046/J.1365-2265.1998.00332.X  0.303
1998 Zhang X, Hinton DR, Park S, Parra B, Liao CL, Lai MM, Stohlman SA. Expression of hemagglutinin/esterase by a mouse hepatitis virus coronavirus defective-interfering RNA alters viral pathogenesis. Virology. 242: 170-83. PMID 9501044 DOI: 10.1006/Viro.1997.8993  0.302
1998 Hinton DR, He S, Lopez PF. Apoptosis in surgically excised choroidal neovascular membranes in age-related macular degeneration. Archives of Ophthalmology (Chicago, Ill. : 1960). 116: 203-9. PMID 9488273 DOI: 10.1001/Archopht.116.2.203  0.312
1997 Zhang W, Law RE, Hinton DR, Couldwell WT. Inhibition of human malignant glioma cell motility and invasion in vitro by hypericin, a potent protein kinase C inhibitor. Cancer Letters. 120: 31-8. PMID 9570383 DOI: 10.1016/S0304-3835(97)00287-5  0.336
1997 Kimura H, Harris MS, Sakamoto T, Gopalakrishna R, Gundimeda U, Cui JZ, Spee C, Hinton DR, Ryan SJ. Hypericin inhibits choroidal endothelial cell proliferation and cord formation in vitro. Current Eye Research. 16: 967-72. PMID 9330847 DOI: 10.1076/Ceyr.16.10.967.9019  0.318
1997 Zhang X, Hinton DR, Cua DJ, Stohlman SA, Lai MM. Expression of interferon-gamma by a coronavirus defective-interfering RNA vector and its effect on viral replication, spread, and pathogenicity. Virology. 233: 327-38. PMID 9217056 DOI: 10.1006/Viro.1997.8598  0.307
1997 Chen TC, Hinton DR, Sippy BD, Hofman FM. Soluble TNF-alpha receptors are constitutively shed and downregulate adhesion molecule expression in malignant gliomas. Journal of Neuropathology and Experimental Neurology. 56: 541-50. PMID 9143267 DOI: 10.1097/00005072-199705000-00010  0.345
1997 Chen TC, Hinton DR, Yong VW, Hofman FM. TGF-B2 and soluble p55 TNFR modulate VCAM-1 expression in glioma cells and brain derived endothelial cells. Journal of Neuroimmunology. 73: 155-61. PMID 9058771 DOI: 10.1016/S0165-5728(96)00190-7  0.367
1997 Lin MT, Stohlman SA, Hinton DR. Mouse hepatitis virus is cleared from the central nervous systems of mice lacking perforin-mediated cytolysis. Journal of Virology. 71: 383-91. PMID 8985361 DOI: 10.1128/Jvi.71.1.383-391.1997  0.308
1996 Sippy BD, Hofman FM, Wright AD, He S, Ryan SJ, Hinton DR. Soluble tumor necrosis factor receptors are present in human vitreous and shed by retinal pigment epithelial cells. Experimental Eye Research. 63: 311-7. PMID 8943704 DOI: 10.1006/Exer.1996.0120  0.328
1996 Kimura H, Sakamoto T, Cardillo JA, Spee C, Hinton DR, Gordon EM, Anderson WF, Ryan SJ. Retrovirus-mediated suicide gene transduction in the vitreous cavity of the eye: feasibility in prevention of proliferative vitreoretinopathy. Human Gene Therapy. 7: 799-808. PMID 8860832 DOI: 10.1089/Hum.1996.7.7-799  0.383
1996 Hamilton HB, Hinton DR, Law RE, Gopalakrishna R, Su YZ, Chen ZH, Weiss MH, Couldwell WT. Inhibition of cellular growth and induction of apoptosis in pituitary adenoma cell lines by the protein kinase C inhibitor hypericin: potential therapeutic application. Journal of Neurosurgery. 85: 329-34. PMID 8755764 DOI: 10.3171/Jns.1996.85.2.0329  0.36
1996 Couldwell WT, Law RE, Hinton DR, Gopalakrishna R, Yong VW, Weiss MH. Protein kinase C and growth regulation of pituitary adenomas. Acta Neurochirurgica. Supplement. 65: 22-6. PMID 8738488 DOI: 10.1007/978-3-7091-9450-8_8  0.313
1996 Sakamoto T, Hinton DR, Kimura H, Spee C, Gopalakrishna R, Ryan SJ. Vitamin E succinate inhibits proliferation and migration of retinal pigment epithelial cells in vitro: therapeutic implication for proliferative vitreoretinopathy. Graefe's Archive For Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fã¼R Klinische Und Experimentelle Ophthalmologie. 234: 186-92. PMID 8720718 DOI: 10.1007/Bf00462031  0.309
1996 Harris MS, Sakamoto T, Kimura H, He S, Spee C, Gopalakrishna R, Gundimeda U, Yoo JS, Hinton DR, Ryan SJ. Hypericin inhibits cell growth and induces apoptosis in retinal pigment epithelial cells: possible involvement of protein kinase C. Current Eye Research. 15: 255-62. PMID 8654105 DOI: 10.3109/02713689609007619  0.374
1996 Lopez PF, Sippy BD, Lambert HM, Thach AB, Hinton DR. Transdifferentiated retinal pigment epithelial cells are immunoreactive for vascular endothelial growth factor in surgically excised age-related macular degeneration-related choroidal neovascular membranes. Investigative Ophthalmology & Visual Science. 37: 855-68. PMID 8603870 DOI: 10.1097/00006982-199805000-00035  0.34
1995 Stohlman SA, Yao Q, Bergmann CC, Tahara SM, Kyuwa S, Hinton DR. Transcription and translation of proinflammatory cytokines following JHMV infection. Advances in Experimental Medicine and Biology. 380: 173-8. PMID 8830475 DOI: 10.1007/978-1-4615-1899-0_28  0.305
1995 Sippy BD, Hofman FM, Wallach D, Hinton DR. Increased expression of tumor necrosis factor-alpha receptors in the brains of patients with AIDS. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association. 10: 511-21. PMID 8548330 DOI: 10.1097/00042560-199510050-00004  0.304
1995 Sakamoto T, Sakamoto H, Hinton DR, Spee C, Ishibashi T, Ryan SJ. In vitro studies of human choroidal endothelial cells. Current Eye Research. 14: 621-7. PMID 8529396 DOI: 10.3109/02713689508998488  0.364
1995 Couldwell WT, Weiss MH, Law RE, Hinton DR. Paradoxical elevation of Ki-67 labeling with protein kinase inhibition in malignant gliomas. Journal of Neurosurgery. 82: 461-8. PMID 7861225 DOI: 10.3171/Jns.1995.82.3.0461  0.329
1995 Sakamoto T, Hinton DR, Sakamoto H, Gopalakrishna R, Ryan SJ, McDonnell PJ. Thrombin induced cytoskeletal change in cultured bovine corneal endothelial cells mediated via protein kinase C pathway. Current Eye Research. 14: 35-45. PMID 7720404 DOI: 10.3109/02713689508999912  0.329
1995 Cua DJ, Hinton DR, Kirkman L, Stohlman SA. Macrophages regulate induction of delayed-type hypersensitivity and experimental allergic encephalomyelitis in SJL mice. European Journal of Immunology. 25: 2318-24. PMID 7664794 DOI: 10.1002/Eji.1830250830  0.304
1995 Murphy TL, Sakamoto T, Hinton DR, Spee C, Gundimeda U, Soriano D, Gopalakrishna R, Ryan SJ. Migration of retinal pigment epithelium cells in vitro is regulated by protein kinase C. Experimental Eye Research. 60: 683-95. PMID 7641851 DOI: 10.1016/S0014-4835(05)80010-7  0.354
1995 Cantin EM, Hinton DR, Chen J, Openshaw H. Gamma interferon expression during acute and latent nervous system infection by herpes simplex virus type 1. Journal of Virology. 69: 4898-905. PMID 7609058 DOI: 10.1128/Jvi.69.8.4898-4905.1995  0.335
1995 Sippy BD, Hofman FM, He S, Osusky R, Sheu SJ, Walker SM, Ryan SJ, Hinton DR. SV40-immortalized and primary cultured human retinal pigment epithelial cells share similar patterns of cytokine-receptor expression and cytokine responsiveness. Current Eye Research. 14: 495-503. PMID 7545567 DOI: 10.3109/02713689509003761  0.345
1995 Sakamoto T, Sakamoto H, Murphy TL, Spee C, Soriano D, Ishibashi T, Hinton DR, Ryan SJ. Vessel formation by choroidal endothelial cells in vitro is modulated by retinal pigment epithelial cells. Archives of Ophthalmology. 113: 512-20. PMID 7536000 DOI: 10.1001/Archopht.1995.01100040134039  0.38
1994 Couldwell WT, Hinton DR, He S, Chen TC, Sebat I, Weiss MH, Law RE. Protein kinase C inhibitors induce apoptosis in human malignant glioma cell lines. Febs Letters. 345: 43-6. PMID 8194597 DOI: 10.1016/0014-5793(94)00415-3  0.311
1994 He S, Wang HM, Ye J, Ogden TE, Ryan SJ, Hinton DR. Dexamethasone induced proliferation of cultured retinal pigment epithelial cells. Current Eye Research. 13: 257-61. PMID 8033587 DOI: 10.3109/02713689408995786  0.381
1994 Sakamoto T, Hinton DR, Sakamoto H, Oganesian A, Kohen L, Gopalakrishna R, Ryan SJ. Collagen gel contraction induced by retinal pigment epithelial cells and choroidal fibroblasts involves the protein kinase C pathway. Current Eye Research. 13: 451-9. PMID 7924409 DOI: 10.3109/02713689408999873  0.342
1994 Kureshi SA, Hofman FM, Schneider JH, Chin LS, Apuzzo ML, Hinton DR. Cytokine expression in radiation-induced delayed cerebral injury. Neurosurgery. 35: 822-9; discussion 82. PMID 7838329 DOI: 10.1227/00006123-199411000-00004  0.326
1994 Jones KD, Couldwell WT, Hinton DR, Su Y, He S, Anker L, Law RE. Lovastatin induces growth inhibition and apoptosis in human malignant glioma cells. Biochemical and Biophysical Research Communications. 205: 1681-7. PMID 7811252 DOI: 10.1006/Bbrc.1994.2861  0.335
1994 Couldwell WT, Gopalakrishna R, Hinton DR, He S, Weiss MH, Law RE, Apuzzo ML, Law RE. Hypericin: a potential antiglioma therapy. Neurosurgery. 35: 705-9; discussion 70. PMID 7808614 DOI: 10.1227/00006123-199410000-00017  0.33
1994 Sheu SJ, Sakamoto T, Osusky R, Wang HM, Ogden TE, Ryan SJ, Hinton DR, Gopalakrishna R. Transforming growth factor-beta regulates human retinal pigment epithelial cell phagocytosis by influencing a protein kinase C-dependent pathway. Graefe's Archive For Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fã¼R Klinische Und Experimentelle Ophthalmologie. 232: 695-701. PMID 7531168 DOI: 10.1007/Bf00171387  0.315
1994 Hofman FM, Dohadwala MM, Wright AD, Hinton DR, Walker SM. Exogenous tat protein activates central nervous system-derived endothelial cells. Journal of Neuroimmunology. 54: 19-28. PMID 7523444 DOI: 10.1016/0165-5728(94)90226-7  0.335
1993 Chen TC, Hinton DR, Apuzzo ML, Hofman FM. Differential effects of tumor necrosis factor-alpha on proliferation, cell surface antigen expression, and cytokine interactions in malignant gliomas. Neurosurgery. 32: 85-94. PMID 8093640 DOI: 10.1227/00006123-199301000-00013  0.325
1992 Schneider J, Hofman FM, Apuzzo ML, Hinton DR. Cytokines and immunoregulatory molecules in malignant glial neoplasms. Journal of Neurosurgery. 77: 265-73. PMID 1625016 DOI: 10.3171/Jns.1992.77.2.0265  0.326
1992 Merrill JE, Kono DH, Clayton J, Ando DG, Hinton DR, Hofman FM. Inflammatory leukocytes and cytokines in the peptide-induced disease of experimental allergic encephalomyelitis in SJL and B10.PL mice. Proceedings of the National Academy of Sciences of the United States of America. 89: 574-8. PMID 1370583 DOI: 10.1073/Pnas.89.2.574  0.337
1991 Hofman FM, Hinton DR, Baemayr J, Weil M, Merrill JE. Lymphokines and immunoregulatory molecules in subacute sclerosing panencephalitis. Clinical Immunology and Immunopathology. 58: 331-42. PMID 1900461 DOI: 10.1016/0090-1229(91)90124-S  0.308
1989 Blanks JC, Hinton DR, Sadun AA, Miller CA. Retinal ganglion cell degeneration in Alzheimer's disease. Brain Research. 501: 364-72. PMID 2819446 DOI: 10.1016/0006-8993(89)90653-7  0.305
1987 Sheridan FP, Miller CA, Blanks JC, Hinton DR. CELL-SUBSET SPECIFIC ANTIGENS IN DEVELOPING MOUSE AND HUMAN RETINA Journal of Neuropathology and Experimental Neurology. 46: 362. DOI: 10.1097/00005072-198705000-00097  0.321
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