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Andy Hudmon - Publications

Affiliations: 
Neuroscience Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Neuroscience Biology, Genetics, General Biology
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54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Zybura AS, Sahoo FK, Hudmon A, Cummins TR. CaMKII Inhibition Attenuates Distinct Gain-of-Function Effects Produced by Mutant Nav1.6 Channels and Reduces Neuronal Excitability. Cells. 11. PMID 35805192 DOI: 10.3390/cells11132108  0.347
2021 Zybura A, Hudmon A, Cummins TR. Distinctive Properties and Powerful Neuromodulation of Na1.6 Sodium Channels Regulates Neuronal Excitability. Cells. 10. PMID 34202119 DOI: 10.3390/cells10071595  0.303
2020 Zybura AS, Baucum AJ, Rush AM, Cummins TR, Hudmon A. CaMKII enhances voltage-gated sodium channel Nav1.6 activity and neuronal excitability. The Journal of Biological Chemistry. PMID 32611770 DOI: 10.1074/Jbc.Ra120.014062  0.403
2018 Shugg T, Johnson DE, Shao M, Lai X, Witzmann F, Cummins TR, Rubart-Von-der Lohe M, Hudmon A, Overholser BR. Calcium/Calmodulin-Dependent Protein Kinase II Regulation of IKs during Sustained Beta-Adrenergic Receptor Stimulation. Heart Rhythm. PMID 29410121 DOI: 10.1016/J.Hrthm.2018.01.024  0.399
2018 Lee WH, Li LL, Chawla A, Hudmon A, Lai YY, Courtney MJ, Hohmann AG. Disruption of nNOS-NOS1AP protein-protein interactions suppresses neuropathic pain in mice. Pain. PMID 29319606 DOI: 10.1097/J.Pain.0000000000001152  0.406
2017 Johnson DE, Hudmon A. Activation State-Dependent Substrate Gating in Ca2+/Calmodulin-Dependent Protein Kinase II. Neural Plasticity. 2017: 9601046. PMID 29391954 DOI: 10.1155/2017/9601046  0.459
2017 Zhou D, Springer MZ, Xu D, Liu D, Hudmon A, Macleod KF, Meroueh SO. Small molecules inhibit STAT3 activation, autophagy, and cancer cell anchorage-independent growth. Bioorganic & Medicinal Chemistry. PMID 28438385 DOI: 10.1016/J.Bmc.2017.03.048  0.333
2017 Xu D, Li L, Zhou D, Liu D, Hudmon A, Meroueh S. Structure-Based Target-Specific Screening Leads to Small-Molecule CaMKIIInhibitors. Chemmedchem. PMID 28371191 DOI: 10.1002/Cmdc.201600636  0.375
2017 Johnson DE, Ramaswamy SS, Hudmon A. Dynamic Substrate Gating in CaMKII by Autophosphorylation Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.2167  0.383
2016 Chawla AR, Johnson DE, Zybura AS, Leeds BP, Nelson RM, Hudmon A. Constitutive Regulation of the Glutamate/Aspartate Transporter EAAT1 by Calcium/Calmodulin-Dependent Protein Kinase II. Journal of Neurochemistry. PMID 27889915 DOI: 10.1111/Jnc.13913  0.417
2016 Malty RH, Hudmon A, Fehrenbacher JC, Vasko MR. Long-term exposure to PGE2 causes homologous desensitization of receptor-mediated activation of protein kinase A. Journal of Neuroinflammation. 13: 181. PMID 27400965 DOI: 10.1186/S12974-016-0645-0  0.403
2016 Pei Z, Xiao Y, Meng J, Hudmon A, Cummins TR. Cardiac sodium channel palmitoylation regulates channel availability and myocyte excitability with implications for arrhythmia generation. Nature Communications. 7: 12035. PMID 27337590 DOI: 10.1038/Ncomms12035  0.335
2016 Zhou C, Ramaswamy SS, Johnson DE, Vitturi DA, Schopfer FJ, Freeman BA, Hudmon A, Levitan ES. Novel Roles for Peroxynitrite in Angiotensin II and CaMKII Signaling. Scientific Reports. 6: 23416. PMID 27079272 DOI: 10.1038/Srep23416  0.353
2015 Gaji RY, Johnson DE, Treeck M, Wang M, Hudmon A, Arrizabalaga G. Phosphorylation of a Myosin Motor by TgCDPK3 Facilitates Rapid Initiation of Motility during Toxoplasma gondii egress. Plos Pathogens. 11: e1005268. PMID 26544049 DOI: 10.1371/Journal.Ppat.1005268  0.397
2015 Yu H, Pan B, Weyer A, Wu HE, Meng J, Fischer G, Vilceanu D, Light AR, Stucky C, Rice FL, Hudmon A, Hogan Q. CaMKII Controls Whether Touch Is Painful. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 14086-102. PMID 26490852 DOI: 10.1523/Jneurosci.1969-15.2015  0.372
2015 Lee WH, Xu Z, Ashpole NM, Hudmon A, Kulkarni PM, Thakur GA, Lai YY, Hohmann AG. Small molecule inhibitors of PSD95-nNOS protein-protein interactions as novel analgesics. Neuropharmacology. PMID 26071110 DOI: 10.1016/J.Neuropharm.2015.05.038  0.641
2015 Bangaru ML, Meng J, Kaiser DJ, Yu H, Fischer G, Hogan QH, Hudmon A. Differential expression of CaMKII isoforms and overall kinase activity in rat dorsal root ganglia after injury. Neuroscience. 300: 116-27. PMID 25982557 DOI: 10.1016/J.Neuroscience.2015.05.007  0.389
2015 Otmakhov N, Gorbacheva EV, Regmi S, Yasuda R, Hudmon A, Lisman J. Excitotoxic insult results in a long-lasting activation of CaMKIIα and mitochondrial damage in living hippocampal neurons. Plos One. 10: e0120881. PMID 25793533 DOI: 10.1371/Journal.Pone.0120881  0.418
2015 Bouchut A, Chawla AR, Jeffers V, Hudmon A, Sullivan WJ. Proteome-wide lysine acetylation in cortical astrocytes and alterations that occur during infection with brain parasite Toxoplasma gondii. Plos One. 10: e0117966. PMID 25786129 DOI: 10.1371/Journal.Pone.0117966  0.308
2015 Tong CW, Wu X, Liu Y, Rosas PC, Sadayappan S, Hudmon A, Muthuchamy M, Powers PA, Valdivia HH, Moss RL. Phosphoregulation of Cardiac Inotropy via Myosin Binding Protein-C During Increased Pacing Frequency or β1-Adrenergic Stimulation. Circulation. Heart Failure. 8: 595-604. PMID 25740838 DOI: 10.1161/Circheartfailure.114.001585  0.342
2014 Ramalingam L, Lu J, Hudmon A, Thurmond DC. Doc2b serves as a scaffolding platform for concurrent binding of multiple Munc18 isoforms in pancreatic islet β-cells. The Biochemical Journal. 464: 251-8. PMID 25190515 DOI: 10.1042/Bj20140845  0.316
2014 Kostic S, Pan B, Guo Y, Yu H, Sapunar D, Kwok WM, Hudmon A, Wu HE, Hogan QH. Regulation of voltage-gated Ca(2+) currents by Ca(2+)/calmodulin-dependent protein kinase II in resting sensory neurons. Molecular and Cellular Neurosciences. 62: 10-8. PMID 25064143 DOI: 10.1016/J.Mcn.2014.07.004  0.483
2014 Chawla A, Johnson D, Hudmon A. Mechanisms Underlying CaMKII Regulation of Astrocytic Glutamate Transporters Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.646  0.436
2014 Johnson DE, Meng J, Hudmon A. Mechanisms Underlying Cooperativity in CaMKII Autophosphorylation and Substrate Phosphorylation Biophysical Journal. 106: 528a. DOI: 10.1016/J.Bpj.2013.11.2946  0.438
2013 Adler JJ, Johnson DE, Heller BL, Bringman LR, Ranahan WP, Conwell MD, Sun Y, Hudmon A, Wells CD. Serum deprivation inhibits the transcriptional co-activator YAP and cell growth via phosphorylation of the 130-kDa isoform of Angiomotin by the LATS1/2 protein kinases. Proceedings of the National Academy of Sciences of the United States of America. 110: 17368-73. PMID 24101513 DOI: 10.1073/Pnas.1308236110  0.391
2013 Ashpole NM, Chawla AR, Martin MP, Brustovetsky T, Brustovetsky N, Hudmon A. Loss of calcium/calmodulin-dependent protein kinase II activity in cortical astrocytes decreases glutamate uptake and induces neurotoxic release of ATP. The Journal of Biological Chemistry. 288: 14599-611. PMID 23543737 DOI: 10.1074/Jbc.M113.466235  0.7
2013 Johnson DE, Kaiser DJ, McBride NM, Hudmon A. The Multimeric Architecture of CaMKII Alters Substrate Regulation of Diffusion-Restricted Environments Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.584  0.445
2012 Tang Q, Bangaru ML, Kostic S, Pan B, Wu HE, Koopmeiners AS, Yu H, Fischer GJ, McCallum JB, Kwok WM, Hudmon A, Hogan QH. Ca²⁺-dependent regulation of Ca²⁺ currents in rat primary afferent neurons: role of CaMKII and the effect of injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 11737-49. PMID 22915116 DOI: 10.1523/Jneurosci.0983-12.2012  0.39
2012 Song W, Xiao Y, Chen H, Ashpole NM, Piekarz AD, Ma P, Hudmon A, Cummins TR, Shou W. The human Nav1.5 F1486 deletion associated with long QT syndrome leads to impaired sodium channel inactivation and reduced lidocaine sensitivity. The Journal of Physiology. 590: 5123-39. PMID 22826127 DOI: 10.1113/Jphysiol.2012.235374  0.63
2012 Ashpole NM, Herren AW, Ginsburg KS, Brogan JD, Johnson DE, Cummins TR, Bers DM, Hudmon A. Ca2+/calmodulin-dependent protein kinase II (CaMKII) regulates cardiac sodium channel NaV1.5 gating by multiple phosphorylation sites. The Journal of Biological Chemistry. 287: 19856-69. PMID 22514276 DOI: 10.1074/Jbc.M111.322537  0.641
2012 Ashpole NM, Song W, Brustovetsky T, Engleman EA, Brustovetsky N, Cummins TR, Hudmon A. Calcium/calmodulin-dependent protein kinase II (CaMKII) inhibition induces neurotoxicity via dysregulation of glutamate/calcium signaling and hyperexcitability. The Journal of Biological Chemistry. 287: 8495-506. PMID 22253441 DOI: 10.1074/Jbc.M111.323915  0.711
2012 Ashpole NM, Song W, Brustovetsky T, Brustovetsky N, Hudmon A. CaMKII Regulation of Calcium Homeostasis and Neuronal Activity Biophysical Journal. 102: 509a. DOI: 10.1016/J.Bpj.2011.11.2789  0.695
2012 Johnson DE, Kaiser DJ, Ashpole NM, Hudmon A. Structural and Catalytic Mechanisms Underlying CaMKII Substrate Selection Biophysical Journal. 102: 271a. DOI: 10.1016/J.Bpj.2011.11.1494  0.67
2011 Brittain JM, Chen L, Wilson SM, Brustovetsky T, Gao X, Ashpole NM, Molosh AI, You H, Hudmon A, Shekhar A, White FA, Zamponi GW, Brustovetsky N, Chen J, Khanna R. Neuroprotection against traumatic brain injury by a peptide derived from the collapsin response mediator protein 2 (CRMP2). The Journal of Biological Chemistry. 286: 37778-92. PMID 21832084 DOI: 10.1074/Jbc.M111.255455  0.679
2011 Coultrap SJ, Vest RS, Ashpole NM, Hudmon A, Bayer KU. CaMKII in cerebral ischemia. Acta Pharmacologica Sinica. 32: 861-72. PMID 21685929 DOI: 10.1038/Aps.2011.68  0.702
2011 Brittain JM, Duarte DB, Wilson SM, Zhu W, Ballard C, Johnson PL, Liu N, Xiong W, Ripsch MS, Wang Y, Fehrenbacher JC, Fitz SD, Khanna M, Park CK, Schmutzler BS, ... ... Hudmon A, et al. Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca²⁺ channel complex. Nature Medicine. 17: 822-9. PMID 21642979 DOI: 10.1038/Nm.2345  0.66
2011 Li L, Khanna M, Jo I, Wang F, Ashpole NM, Hudmon A, Meroueh SO. Target-specific support vector machine scoring in structure-based virtual screening: computational validation, in vitro testing in kinases, and effects on lung cancer cell proliferation. Journal of Chemical Information and Modeling. 51: 755-9. PMID 21438548 DOI: 10.1021/Ci100490W  0.627
2011 Ashpole NM, Hudmon A. Excitotoxic neuroprotection and vulnerability with CaMKII inhibition. Molecular and Cellular Neurosciences. 46: 720-30. PMID 21316454 DOI: 10.1016/J.Mcn.2011.02.003  0.703
2011 Ashpole NM, Johnson DE, Hudmon A. Molecular Mechanism of Alpha-CaMKII Self-Association Biophysical Journal. 100: 85a-86a. DOI: 10.1016/J.Bpj.2010.12.672  0.625
2011 Herren AW, Ashpole NM, Ginsburg KS, Bers DM, Hudmon A. CaMKII Regulates Cardiac Sodium Channel Nav1.5 by Phosphorylation in the Loop Between Domain I and II Biophysical Journal. 100: 421a. DOI: 10.1016/J.Bpj.2010.12.2491  0.677
2008 Hudmon A, Choi JS, Tyrrell L, Black JA, Rush AM, Waxman SG, Dib-Hajj SD. Phosphorylation of sodium channel Na(v)1.8 by p38 mitogen-activated protein kinase increases current density in dorsal root ganglion neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 3190-201. PMID 18354022 DOI: 10.1523/Jneurosci.4403-07.2008  0.432
2007 Yu X, Sun JP, He Y, Guo X, Liu S, Zhou B, Hudmon A, Zhang ZY. Structure, inhibitor, and regulatory mechanism of Lyp, a lymphoid-specific tyrosine phosphatase implicated in autoimmune diseases. Proceedings of the National Academy of Sciences of the United States of America. 104: 19767-72. PMID 18056643 DOI: 10.1073/Pnas.0706233104  0.401
2007 Merrill MA, Malik Z, Akyol Z, Bartos JA, Leonard AS, Hudmon A, Shea MA, Hell JW. Displacement of alpha-actinin from the NMDA receptor NR1 C0 domain By Ca2+/calmodulin promotes CaMKII binding. Biochemistry. 46: 8485-97. PMID 17602661 DOI: 10.1021/Bi0623025  0.335
2006 Choi JS, Hudmon A, Waxman SG, Dib-Hajj SD. Calmodulin regulates current density and frequency-dependent inhibition of sodium channel Nav1.8 in DRG neurons. Journal of Neurophysiology. 96: 97-108. PMID 16598065 DOI: 10.1152/jn.00854.2005  0.332
2005 Hudmon A, Schulman H, Kim J, Maltez JM, Tsien RW, Pitt GS. CaMKII tethers to L-type Ca2+ channels, establishing a local and dedicated integrator of Ca2+ signals for facilitation. The Journal of Cell Biology. 171: 537-47. PMID 16275756 DOI: 10.1083/Jcb.200505155  0.386
2005 Hudmon A, Lebel E, Roy H, Sik A, Schulman H, Waxham MN, De Koninck P. A mechanism for Ca2+/calmodulin-dependent protein kinase II clustering at synaptic and nonsynaptic sites based on self-association. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6971-83. PMID 16049173 DOI: 10.1523/Jneurosci.4698-04.2005  0.442
2005 Wittmack EK, Rush AM, Hudmon A, Waxman SG, Dib-Hajj SD. Voltage-gated sodium channel Nav1.6 is modulated by p38 mitogen-activated protein kinase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6621-30. PMID 16014723 DOI: 10.1523/Jneurosci.0541-05.2005  0.343
2002 Hudmon A, Schulman H. Neuronal CA2+/calmodulin-dependent protein kinase II: the role of structure and autoregulation in cellular function. Annual Review of Biochemistry. 71: 473-510. PMID 12045104 DOI: 10.1146/Annurev.Biochem.71.110601.135410  0.447
2002 Hudmon A, Schulman H. Structure-function of the multifunctional Ca2+/calmodulin-dependent protein kinase II. The Biochemical Journal. 364: 593-611. PMID 11931644 DOI: 10.1042/Bj20020228  0.397
2002 Bradshaw JM, Hudmon A, Schulman H. Chemical quenched flow kinetic studies indicate an intraholoenzyme autophosphorylation mechanism for Ca2+/calmodulin-dependent protein kinase II. The Journal of Biological Chemistry. 277: 20991-8. PMID 11925447 DOI: 10.1074/Jbc.M202154200  0.41
2001 Pitt GS, Zühlke RD, Hudmon A, Schulman H, Reuter H, Tsien RW. Molecular basis of calmodulin tethering and Ca2+-dependent inactivation of L-type Ca2+ channels. The Journal of Biological Chemistry. 276: 30794-802. PMID 11408490 DOI: 10.1074/Jbc.M104959200  0.335
2001 Singla SI, Hudmon A, Goldberg JM, Smith JL, Schulman H. Molecular characterization of calmodulin trapping by calcium/calmodulin-dependent protein kinase II. The Journal of Biological Chemistry. 276: 29353-60. PMID 11384969 DOI: 10.1074/Jbc.M101744200  0.415
2001 Hudmon A, Kim SA, Kolb SJ, Stoops JK, Waxham MN. Light scattering and transmission electron microscopy studies reveal a mechanism for calcium/calmodulin-dependent protein kinase II self-association. Journal of Neurochemistry. 76: 1364-75. PMID 11238721 DOI: 10.1046/J.1471-4159.2001.00119.X  0.381
1995 Kolb SJ, Hudmon A, Waxham MN. Ca2+/calmodulin kinase II translocates in a hippocampal slice model of ischemia. Journal of Neurochemistry. 64: 2147-56. PMID 7722499 DOI: 10.1046/J.1471-4159.1995.64052147.X  0.3
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