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Robert F. Siliciano - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Immunology, Microbiology Biology
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358 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Lim SY, Lee J, Osuna CE, Vikhe P, Schalk DR, Chen E, Fray E, Kumar M, Schultz-Darken N, Rakasz E, Capuano S, Ladd RA, Gil HM, Evans DT, Jeng EK, ... ... Siliciano R, et al. Induction of durable remission by dual immunotherapy in SHIV-infected ART-suppressed macaques. Science (New York, N.Y.). eadf7966. PMID 38422185 DOI: 10.1126/science.adf7966  0.479
2024 Reeves DB, Rigau DN, Romero A, Zhang H, Simonetti FR, Varriale J, Hoh R, Zhang L, Smith KN, Montaner LJ, Rubin LH, Gange SJ, Roan NR, Tien PC, Margolick JB, ... ... Siliciano RF, et al. Mild HIV-specific selective forces overlaying natural CD4+ T cell dynamics explain the clonality and decay dynamics of HIV reservoir cells. Medrxiv : the Preprint Server For Health Sciences. PMID 38405967 DOI: 10.1101/2024.02.13.24302704  0.592
2024 Siliciano JD, Siliciano RF. HIV cure: The daunting scale of the problem. Science (New York, N.Y.). 383: 703-705. PMID 38359111 DOI: 10.1126/science.adk1831  0.403
2024 Board NL, Yuan Z, Wu F, Moskovljevic M, Ravi M, Sengupta S, Mun SS, Simonetti FR, Lai J, Tebas P, Lynn K, Hoh R, Deeks SG, Siliciano JD, Montaner LJ, ... Siliciano RF, et al. Bispecific antibodies promote natural killer cell-mediated elimination of HIV-1 reservoir cells. Nature Immunology. PMID 38278966 DOI: 10.1038/s41590-023-01741-5  0.614
2024 Kufera JT, Armstrong C, Wu F, Singhal A, Zhang H, Lai J, Wilkins HN, Simonetti FR, Siliciano JD, Siliciano RF. CD4+ T cells with latent HIV-1 have reduced proliferative responses to T cell receptor stimulation. The Journal of Experimental Medicine. 221. PMID 38270554 DOI: 10.1084/jem.20231511  0.47
2023 Sambaturu N, Fray EJ, Wu F, Zitzmann C, Simonetti FR, Barouch DH, Siliciano JD, Siliciano RF, Ribeiro RM, Perelson AS, Molina-París C, Leitner T. Last in first out: SIV proviruses seeded later in infection are harbored in short-lived CD4 T cells. Biorxiv : the Preprint Server For Biology. PMID 37961482 DOI: 10.1101/2023.11.03.565539  0.567
2023 Kumar MR, Fray EJ, Bender AM, Zitzmann C, Ribeiro RM, Perelson AS, Barouch DH, Siliciano JD, Siliciano RF. Biphasic decay of intact SHIV genomes following initiation of antiretroviral therapy complicates analysis of interventions targeting the reservoir. Proceedings of the National Academy of Sciences of the United States of America. 120: e2313209120. PMID 37844236 DOI: 10.1073/pnas.2313209120  0.487
2023 Mainou E, Berendam SJ, Obregon-Perko V, Uffman EA, Phan CT, Shaw GM, Bar KJ, Kumar MR, Fray EJ, Siliciano JM, Siliciano RF, Silvestri G, Permar SR, Fouda GG, McCarthy J, et al. Assessing the effect of antibody responses on viral rebound dynamics in postnatally SHIV-infected infant Rhesus macaques. Biorxiv : the Preprint Server For Biology. PMID 37502921 DOI: 10.1101/2023.07.22.550159  0.413
2023 McMyn NF, Varriale J, Fray EJ, Zitzmann C, MacLeod HJ, Lai J, Singhal A, Moskovljevic M, Garcia MA, Lopez BM, Hariharan V, Rhodehouse K, Lynn K, Tebas P, Mounzer K, ... ... Siliciano R, et al. The latent reservoir of inducible, infectious HIV-1 does not decrease despite decades of antiretroviral therapy. The Journal of Clinical Investigation. PMID 37463049 DOI: 10.1172/JCI171554  0.453
2023 Benner SE, Zhu X, Hussain S, Florman S, Eby Y, Fernandez RE, Ostrander D, Rana M, Ottmann S, Hand J, Price JC, Pereira MR, Wojciechowski D, Simkins J, Stosor V, ... ... Siliciano R, et al. HIV-positive liver transplant does not alter the latent viral reservoir in recipients with ART-suppressed HIV. The Journal of Infectious Diseases. PMID 37379584 DOI: 10.1093/infdis/jiad241  0.423
2023 Wu HL, Busman-Sahay K, Weber WC, Waytashek CM, Boyle CD, Bateman KB, Reed JS, Hwang JM, Shriver-Munsch C, Swanson T, Northrup M, Armantrout K, Price H, Robertson-LeVay M, Uttke S, ... ... Siliciano RF, et al. Allogeneic immunity clears latent virus following allogeneic stem cell transplantation in SIV-infected ART-suppressed macaques. Immunity. PMID 37236188 DOI: 10.1016/j.immuni.2023.04.019  0.453
2023 Sanders-Beer BE, Archin NM, Brumme ZL, Busch M, Deleage C, O'Doherty U, Hughes SH, Jerome K, Jones RB, Karn J, Kearney MF, Keele B, Kulpa D, Laird G, Li JZ, ... ... Siliciano RF, et al. Current HIV/SIV Reservoir Assays for Preclinical and Clinical Applications: Recommendations from the Experts 2022 NIAID Workshop Summary. Aids Research and Human Retroviruses. PMID 37126090 DOI: 10.1089/AID.2022.0188  0.491
2023 Sengupta S, Zhang J, Reed MC, Yu J, Kim A, Boronina TN, Board NL, Wrabl JO, Shenderov K, Welsh RA, Yang W, Timmons AE, Hoh R, Cole RN, Deeks SG, ... ... Siliciano RF, et al. A cell-free antigen processing system informs HIV-1 epitope selection and vaccine design. The Journal of Experimental Medicine. 220. PMID 37058141 DOI: 10.1084/jem.20221654  0.779
2023 Fray EJ, Wu F, Simonetti FR, Zitzmann C, Sambaturu N, Molina-Paris C, Bender AM, Liu PT, Ventura JD, Wiseman RW, O'Connor DH, Geleziunas R, Leitner T, Ribeiro RM, Perelson AS, ... ... Siliciano RF, et al. Antiretroviral therapy reveals triphasic decay of intact SIV genomes and persistence of ancestral variants. Cell Host & Microbe. PMID 36809762 DOI: 10.1016/j.chom.2023.01.016  0.484
2023 Lopez B, Siliciano RF. Analyzing the unperturbed HIV-1 T cell reservoir. Trends in Immunology. 44: 147-149. PMID 36739207 DOI: 10.1016/j.it.2023.01.007  0.492
2023 White JA, Wu F, Yasin S, Moskovljevic M, Varriale J, Dragoni F, Camilo Contreras A, Duan J, Zheng MY, Tadzong NF, Patel HB, Quiambao JMC, Rhodehouse K, Zhang H, Lai J, ... ... Siliciano RF, et al. Clonally expanded HIV-1 proviruses with 5'-Leader defects can give rise to nonsuppressible residual viremia. The Journal of Clinical Investigation. PMID 36602866 DOI: 10.1172/JCI165245  0.567
2022 Benner SE, Eby Y, Zhu X, Fernandez RE, Patel EU, Ruff JE, Habtehyimer F, Schmidt HA, Kirby CS, Hussain S, Ostrander D, Desai NM, Florman S, Rana MM, Friedman-Moraco R, ... ... Siliciano RF, et al. The effect of induction immunosuppression for kidney transplant on the latent HIV reservoir. Jci Insight. 7. PMID 36345940 DOI: 10.1172/jci.insight.162968  0.556
2022 Dai W, Wu F, McMyn N, Song B, Walker-Sperling VE, Varriale J, Zhang H, Barouch DH, Siliciano JD, Li W, Siliciano RF. Genome-wide CRISPR screens identify combinations of candidate latency reversing agents for targeting the latent HIV-1 reservoir. Science Translational Medicine. 14: eabh3351. PMID 36260688 DOI: 10.1126/scitranslmed.abh3351  0.532
2022 White JA, Kufera JT, Bachmann N, Dai W, Simonetti FR, Armstrong C, Lai J, Beg S, Siliciano JD, Siliciano RF. Measuring the latent reservoir for HIV-1: Quantification bias in near full-length genome sequencing methods. Plos Pathogens. 18: e1010845. PMID 36074794 DOI: 10.1371/journal.ppat.1010845  0.393
2022 Walker-Sperling VEK, Mercado NB, Chandrashekar A, Borducchi EN, Liu J, Nkolola JP, Lewis M, Murry JP, Yang Y, Geleziunas R, Robb ML, Michael NL, Pau MG, Wegmann F, Schuitemaker H, ... ... Siliciano RF, et al. Therapeutic efficacy of combined active and passive immunization in ART-suppressed, SHIV-infected rhesus macaques. Nature Communications. 13: 3463. PMID 35710819 DOI: 10.1038/s41467-022-31196-5  0.421
2022 Sengupta S, Board NL, Wu F, Moskovljevic M, Douglass J, Zhang J, Reinhold BR, Duke-Cohan J, Yu J, Reed MC, Tabdili Y, Azurmendi A, Fray EJ, Zhang H, Hsiue EH, ... ... Siliciano RF, et al. TCR-mimic bispecific antibodies to target the HIV-1 reservoir. Proceedings of the National Academy of Sciences of the United States of America. 119: e2123406119. PMID 35394875 DOI: 10.1073/pnas.2123406119  0.799
2022 White JA, Simonetti FR, Beg S, McMyn NF, Dai W, Bachmann N, Lai J, Ford WC, Bunch C, Jones JL, Ribeiro RM, Perelson AS, Siliciano JD, Siliciano RF. Complex decay dynamics of HIV virions, intact and defective proviruses, and 2LTR circles following initiation of antiretroviral therapy. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 35110411 DOI: 10.1073/pnas.2120326119  0.474
2021 Board NL, Moskovljevic M, Wu F, Siliciano RF, Siliciano JD. Engaging innate immunity in HIV-1 cure strategies. Nature Reviews. Immunology. PMID 34824401 DOI: 10.1038/s41577-021-00649-1  0.591
2021 Turk G, Seiger K, Lian X, Sun W, Parsons EM, Gao C, Rassadkina Y, Polo ML, Czernikier A, Ghiglione Y, Vellicce A, Varriale J, Lai J, Yuki Y, Martin M, ... ... Siliciano R, et al. A Possible Sterilizing Cure of HIV-1 Infection Without Stem Cell Transplantation. Annals of Internal Medicine. PMID 34781719 DOI: 10.7326/L21-0297  0.466
2021 Siliciano JD, Siliciano RF. In Vivo Dynamics of the Latent Reservoir for HIV-1: New Insights and Implications for Cure. Annual Review of Pathology. 17: 271-294. PMID 34736342 DOI: 10.1146/annurev-pathol-050520-112001  0.56
2021 Rasmussen TA, Rajdev L, Rhodes A, Dantanarayana A, Tennakoon S, Chea S, Spelman T, Lensing S, Rutishauser R, Bakkour S, Busch M, Siliciano JD, Siliciano RF, Einstein MH, Dittmer DP, et al. Impact of anti-PD-1 and anti-CTLA-4 on the HIV reservoir in people living with HIV with cancer on antiretroviral therapy: The AIDS Malignancy Consortium-095 study. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 33677480 DOI: 10.1093/cid/ciaa1530  0.474
2021 Cadena AM, Ventura JD, Abbink P, Borducchi EN, Tuyishime H, Mercado NB, Walker-Sperling V, Siamatu M, Liu PT, Chandrashekar A, Nkolola JP, McMahan K, Kordana N, Hamza V, Bondzie EA, ... ... Siliciano RF, et al. Persistence of viral RNA in lymph nodes in ART-suppressed SIV/SHIV-infected Rhesus Macaques. Nature Communications. 12: 1474. PMID 33674572 DOI: 10.1038/s41467-021-21724-0  0.416
2021 Siliciano JD, Siliciano RF. Low Inducibility of Latent Human Immunodeficiency Virus Type 1 Proviruses as a Major Barrier to Cure. The Journal of Infectious Diseases. 223: 13-21. PMID 33586775 DOI: 10.1093/infdis/jiaa649  0.556
2021 Gondim MVP, Sherrill-Mix S, Bibollet-Ruche F, Russell RM, Trimboli S, Smith AG, Li Y, Liu W, Avitto AN, DeVoto JC, Connell J, Fenton-May AE, Pellegrino P, Williams I, Papasavvas E, ... ... Siliciano RF, et al. Heightened resistance to host type 1 interferons characterizes HIV-1 at transmission and after antiretroviral therapy interruption. Science Translational Medicine. 13. PMID 33441429 DOI: 10.1126/scitranslmed.abd8179  0.626
2020 Gaebler C, Falcinelli SD, Stoffel E, Read J, Murtagh R, Oliveira TY, Ramos V, Lorenzi JCC, Kirchherr J, James KS, Allard B, Baker C, Kuruc JD, Caskey M, Archin NM, ... Siliciano RF, et al. Sequence evaluation and comparative analysis of novel assays for intact proviral HIV-1 DNA. Journal of Virology. PMID 33361426 DOI: 10.1128/JVI.01986-20  0.472
2020 Simonetti FR, Zhang H, Soroosh GP, Duan J, Rhodehouse K, Hill AL, Beg SA, McCormick K, Raymond HE, Nobles CL, Everett JK, Kwon KJ, White JA, Lai J, Margolick JB, ... ... Siliciano RF, et al. Antigen-driven clonal selection shapes the persistence of HIV-1 infected CD4+ T cells in vivo. The Journal of Clinical Investigation. PMID 33301425 DOI: 10.1172/JCI145254  0.581
2020 Martin AR, Bender AM, Hackman J, Kwon KJ, Lynch BA, Bruno D, Martens C, Beg S, Florman SS, Desai N, Segev D, Laird GM, Siliciano JD, Quinn TC, Tobian AAR, ... ... Siliciano RF, et al. Similar frequency and inducibility of intact HIV-1 proviruses in blood and lymph nodes. The Journal of Infectious Diseases. PMID 33269401 DOI: 10.1093/infdis/jiaa736  0.443
2020 Bertagnolli LN, Varriale J, Sweet S, Brockhurst J, Simonetti FR, White J, Beg S, Lynn K, Mounzer K, Frank I, Tebas P, Bar KJ, Montaner LJ, Siliciano RF, Siliciano JD. Autologous IgG antibodies block outgrowth of a substantial but variable fraction of viruses in the latent reservoir for HIV-1. Proceedings of the National Academy of Sciences of the United States of America. PMID 33239444 DOI: 10.1073/pnas.2020617117  0.535
2020 Yukl SA, Khan S, Chen TH, Trapecar M, Wu F, Xie G, Telwatte S, Fulop D, Pico AR, Laird GM, Ritter KD, Jones NG, Lu CM, Siliciano RF, Roan NR, et al. Shared Mechanisms Govern HIV Transcriptional Suppression in Circulating CD103+ and Gut CD4+ T Cells. Journal of Virology. PMID 33115867 DOI: 10.1128/JVI.01331-20  0.59
2020 Obregon-Perko V, Bricker K, Mensah G, Uddin F, Kumar M, Fray E, Siliciano RF, Schoof N, Horner A, Mavigner M, Liang S, Vanderford T, Sass J, Chan C, Berendam SJ, et al. SHIV.C.CH505 Persistence in ART-Suppressed Infant Macaques is Characterized by Elevated SHIV RNA in the Gut and High Abundance of Intact SHIV DNA in Naïve CD4+ T cells. Journal of Virology. PMID 33087463 DOI: 10.1128/JVI.01669-20  0.583
2020 Kirk GD, Astemborski J, Mehta SH, Ritter KD, Laird GM, Bordi R, Sekaly R, Siliciano JD, Siliciano RF. Non-structured treatment interruptions are associated with higher HIV reservoir size measured by intact proviral DNA assay in people who inject drugs. The Journal of Infectious Diseases. PMID 33037877 DOI: 10.1093/infdis/jiaa634  0.54
2020 Siliciano JD, Siliciano RF. Nonsuppressible HIV-1 viremia: a reflection of how the reservoir persists. The Journal of Clinical Investigation. PMID 33016925 DOI: 10.1172/JCI141497  0.647
2020 Song N, Sengupta S, Khoruzhenko S, Welsh RA, Kim A, Kumar MR, Sønder SU, Sidhom JW, Zhang H, Jie C, Siliciano RF, Sadegh-Nasseri S. Multiple genetic programs contribute to CD4 T cell memory differentiation and longevity by maintaining T cell quiescence. Cellular Immunology. 357: 104210. PMID 32987276 DOI: 10.1016/J.Cellimm.2020.104210  0.696
2020 Abdel-Mohsen M, Richman D, Siliciano RF, Nussenzweig MC, Howell BJ, Martinez-Picado J, Chomont N, Bar KJ, Yu XG, Lichterfeld M, Alcami J, Hazuda D, Bushman F, Siliciano JD, Betts MR, et al. Recommendations for measuring HIV reservoir size in cure-directed clinical trials. Nature Medicine. PMID 32895573 DOI: 10.1038/S41591-020-1022-1  0.611
2020 Jiang C, Lian X, Gao C, Sun X, Einkauf KB, Chevalier JM, Chen SMY, Hua S, Rhee B, Chang K, Blackmer JE, Osborn M, Peluso MJ, Hoh R, Somsouk M, ... ... Siliciano RF, et al. Distinct viral reservoirs in individuals with spontaneous control of HIV-1. Nature. PMID 32848246 DOI: 10.1038/S41586-020-2651-8  0.582
2020 Simonetti FR, White JA, Tumiotto C, Ritter KD, Cai M, Gandhi RT, Deeks SG, Howell BJ, Montaner LJ, Blankson JN, Martin A, Laird GM, Siliciano RF, Mellors JW, Siliciano JD. Intact proviral DNA assay analysis of large cohorts of people with HIV provides a benchmark for the frequency and composition of persistent proviral DNA. Proceedings of the National Academy of Sciences of the United States of America. PMID 32690683 DOI: 10.1073/Pnas.2006816117  0.642
2020 Durand CM, Capoferri AA, Redd AD, Zahurak M, Rosenbloom DIS, Cash A, Avery RK, Bolaños-Meade J, Bollard CM, Bullen CK, Flexner C, Fuchs EJ, Gallant J, Gladstone DE, Gocke CD, ... ... Siliciano RF, et al. Allogeneic bone marrow transplantation with post-transplant cyclophosphamide for patients with HIV and haematological malignancies: a feasibility study. The Lancet. Hiv. PMID 32649866 DOI: 10.1016/S2352-3018(20)30073-4  0.474
2020 Timmons A, Fray E, Kumar M, Wu F, Dai W, Bullen CK, Kim P, Hetzel C, Yang C, Beg S, Lai J, Pomerantz JL, Yukl SA, Siliciano JD, Siliciano RF. HSF1 inhibition attenuates HIV-1 latency reversal mediated by several candidate LRAs In Vitro and Ex Vivo. Proceedings of the National Academy of Sciences of the United States of America. PMID 32571938 DOI: 10.1073/Pnas.1916290117  0.649
2020 Antar AAR, Jenike KM, Jang S, Rigau DN, Reeves DB, Hoh R, Krone MR, Keruly JC, Moore RD, Schiffer JT, Nonyane BA, Hecht FM, Deeks SG, Siliciano JD, Ho YC, ... Siliciano RF, et al. Longitudinal study reveals HIV-1-infected CD4+ T cell dynamics during long-term antiretroviral therapy. The Journal of Clinical Investigation. PMID 32191639 DOI: 10.1172/Jci135953  0.683
2020 Peluso MJ, Bacchetti P, Ritter KD, Beg SA, Lai J, Martin JN, Hunt PW, Henrich TJ, Siliciano JD, Siliciano RF, Laird GM, Deeks SG. Differential decay of intact and defective proviral DNA in HIV-1-infected individuals on suppressive antiretroviral therapy. Jci Insight. PMID 32045386 DOI: 10.1016/S2055-6640(20)30130-8  0.572
2020 Kwon KJ, Timmons AE, Sengupta S, Simonetti FR, Zhang H, Hoh R, Deeks SG, Siliciano JD, Siliciano RF. Different human resting memory CD4 T cell subsets show similar low inducibility of latent HIV-1 proviruses. Science Translational Medicine. 12. PMID 31996465 DOI: 10.1126/Scitranslmed.Aax6795  0.605
2019 Silverman K, Holtyn AF, Rodewald AM, Siliciano RF, Jarvis BP, Subramaniam S, Leoutsakos JM, Getty CA, Ruhs S, Marzinke MA, Fingerhood M. Incentives for Viral Suppression in People Living with HIV: A Randomized Clinical Trial. Aids and Behavior. PMID 31297681 DOI: 10.1007/S10461-019-02592-8  0.548
2019 Bender AM, Simonetti FR, Kumar MR, Fray EJ, Bruner KM, Timmons AE, Tai KY, Jenike KM, Antar AAR, Liu PT, Ho YC, Raugi DN, Seydi M, Gottlieb GS, Okoye AA, ... ... Siliciano RF, et al. The Landscape of Persistent Viral Genomes in ART-Treated SIV, SHIV, and HIV-2 Infections. Cell Host & Microbe. 26: 73-85.e4. PMID 31295427 DOI: 10.1016/J.Chom.2019.06.005  0.614
2019 Bruner KM, Wang Z, Simonetti FR, Bender AM, Kwon KJ, Sengupta S, Fray EJ, Beg SA, Antar AAR, Jenike KM, Bertagnolli LN, Capoferri AA, Kufera JT, Timmons A, Nobles C, ... ... Siliciano RF, et al. A quantitative approach for measuring the reservoir of latent HIV-1 proviruses. Nature. PMID 30700913 DOI: 10.1038/S41586-019-0898-8  0.639
2019 Siliciano RF. Reservoirs for HIV-1. Current Infectious Disease Reports. 1: 298-304. PMID 11095802 DOI: 10.1007/S11908-999-0033-3  0.702
2019 Cyktor J, Gandhi R, Bosch R, Mar H, Laird G, Macatangay B, Eron J, Siliciano R, Mcmahon D, Mellors J. Intact proviral DNA levels decline in people with HIV on antiretroviral therapy Journal of Virus Eradication. 5: 38. DOI: 10.1016/S2055-6640(20)30174-6  0.524
2019 Simonetti F, Zhang H, Soroosh G, Beg S, Raymond H, Mccormick K, Deeks S, Bushman F, Siliciano J, Siliciano R. Contribution of antigenic exposure to the persistence of HIV-infected CD4 T cells in vivo Journal of Virus Eradication. 5: 23-24. DOI: 10.1016/S2055-6640(20)30132-1  0.63
2018 Bertagnolli LN, White JA, Simonetti FR, Beg SA, Lai J, Tomescu C, Murray AJ, Antar AAR, Zhang H, Margolick JB, Hoh R, Deeks SG, Tebas P, Montaner LJ, Siliciano RF, et al. The role of CD32 during HIV-1 infection. Nature. 561: E17-E19. PMID 30232425 DOI: 10.1038/S41586-018-0494-3  0.629
2018 Hill AL, Rosenbloom DIS, Nowak MA, Siliciano RF. Insight into treatment of HIV infection from viral dynamics models. Immunological Reviews. 285: 9-25. PMID 30129208 DOI: 10.1111/Imr.12698  0.587
2018 El-Diwany R, Soliman M, Sugawara S, Breitwieser F, Skaist A, Coggiano C, Sangal N, Chattergoon M, Bailey JR, Siliciano RF, Blankson JN, Ray SC, Wheelan SJ, Thomas DL, Balagopal A. CMPK2 and BCL-G are associated with type 1 interferon-induced HIV restriction in humans. Science Advances. 4: eaat0843. PMID 30083606 DOI: 10.1126/Sciadv.Aat0843  0.765
2018 Salantes DB, Zheng Y, Mampe F, Srivastava T, Beg S, Lai J, Li JZ, Tressler RL, Koup RA, Hoxie J, Abdel-Mohsen M, Sherrill-Mix S, McCormick K, Overton ET, Bushman FD, ... ... Siliciano RF, et al. HIV-1 latent reservoir size and diversity are stable following brief treatment interruption. The Journal of Clinical Investigation. PMID 29911997 DOI: 10.1172/Jci120194  0.588
2018 Sengupta S, Siliciano RF. Targeting the Latent Reservoir for HIV-1. Immunity. 48: 872-895. PMID 29768175 DOI: 10.1016/J.Immuni.2018.04.030  0.673
2018 Wang Z, Gurule EE, Brennan TP, Gerold JM, Kwon KJ, Hosmane NN, Kumar MR, Beg SA, Capoferri AA, Ray SC, Ho YC, Hill AL, Siliciano JD, Siliciano RF. Expanded cellular clones carrying replication-competent HIV-1 persist, wax, and wane. Proceedings of the National Academy of Sciences of the United States of America. PMID 29483265 DOI: 10.1073/Pnas.1720665115  0.631
2018 Pohlmeyer CW, Laskey SB, Beck SE, Xu DC, Capoferri AA, Garliss CC, May ME, Livingston A, Lichmira W, Moore RD, Leffell MS, Butler NJ, Thorne JE, Flynn JA, Siliciano RF, et al. Cross-reactive microbial peptides can modulate HIV-specific CD8+ T cell responses. Plos One. 13: e0192098. PMID 29466365 DOI: 10.1371/Journal.Pone.0192098  0.633
2018 Wang Z, Simonetti FR, Siliciano RF, Laird GM. Measuring replication competent HIV-1: advances and challenges in defining the latent reservoir. Retrovirology. 15: 21. PMID 29433524 DOI: 10.1186/S12977-018-0404-7  0.642
2018 Huang SH, Ren Y, Thomas AS, Chan D, Mueller S, Ward AR, Patel S, Bollard CM, Cruz CR, Karandish S, Truong R, Macedo AB, Bosque A, Kovacs C, Benko E, ... ... Siliciano RF, et al. Latent HIV reservoirs exhibit inherent resistance to elimination by CD8+ T cells. The Journal of Clinical Investigation. PMID 29355843 DOI: 10.1172/Jci97555  0.611
2017 Rosenbloom DIS, Hill AL, Laskey SB, Siliciano RF. Re-evaluating evolution in the HIV reservoir. Nature. 551: E6-E9. PMID 29168805 DOI: 10.1038/Nature24634  0.562
2017 Henrich TJ, Hatano H, Bacon O, Hogan LE, Rutishauser R, Hill A, Kearney MF, Anderson EM, Buchbinder SP, Cohen SE, Abdel-Mohsen M, Pohlmeyer CW, Fromentin R, Hoh R, Liu AY, ... ... Siliciano RF, et al. HIV-1 persistence following extremely early initiation of antiretroviral therapy (ART) during acute HIV-1 infection: An observational study. Plos Medicine. 14: e1002417. PMID 29112956 DOI: 10.1371/Journal.Pmed.1002417  0.585
2017 Siliciano JD, Siliciano RF. Assays to Measure Latency, Reservoirs, and Reactivation. Current Topics in Microbiology and Immunology. PMID 29071475 DOI: 10.1007/82_2017_75  0.639
2017 Shan L, Deng K, Gao H, Xing S, Capoferri AA, Durand CM, Rabi SA, Laird GM, Kim M, Hosmane NN, Yang HC, Zhang H, Margolick JB, Li L, Cai W, ... ... Siliciano RF, et al. Transcriptional Reprogramming during Effector-to-Memory Transition Renders CD4(+) T Cells Permissive for Latent HIV-1 Infection. Immunity. 47: 766-775.e3. PMID 29045905 DOI: 10.1016/J.Immuni.2017.09.014  0.859
2017 Hill AL, Rosenbloom DIS, Goldstein E, Hanhauser E, Kuritzkes DR, Siliciano RF, Henrich TJ. Correction: Real-Time Predictions of Reservoir Size and Rebound Time during Antiretroviral Therapy Interruption Trials for HIV. Plos Pathogens. 13: e1006488. PMID 28683094 DOI: 10.1371/journal.ppat.1006488  0.338
2017 Kwon KJ, Siliciano RF. HIV persistence: clonal expansion of cells in the latent reservoir. The Journal of Clinical Investigation. PMID 28628041 DOI: 10.1172/Jci95329  0.685
2017 Prodger JL, Lai J, Reynolds SJ, Keruly JC, Moore RD, Kasule J, Kityamuweesi T, Buule P, Serwadda D, Nason M, Capoferri AA, Porcella SF, Siliciano RF, Redd AD, Siliciano JD, et al. Reduced Frequency of Cells Latently Infected with Replication-Competent HIV-1 in Virally Suppressed Individuals Living in Rakai, Uganda. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 28535179 DOI: 10.1093/Cid/Cix478  0.666
2017 Pollack RA, Jones RB, Pertea M, Bruner KM, Martin AR, Thomas AS, Capoferri AA, Beg SA, Huang SH, Karandish S, Hao H, Halper-Stromberg E, Yong PC, Kovacs C, Benko E, ... Siliciano RF, et al. Defective HIV-1 Proviruses Are Expressed and Can Be Recognized by Cytotoxic T Lymphocytes, which Shape the Proviral Landscape. Cell Host & Microbe. 21: 494-506.e4. PMID 28407485 DOI: 10.1016/J.Chom.2017.03.008  0.649
2017 Hosmane NN, Kwon KJ, Bruner KM, Capoferri AA, Beg S, Rosenbloom DI, Keele BF, Ho YC, Siliciano JD, Siliciano RF. Proliferation of latently infected CD4(+) T cells carrying replication-competent HIV-1: Potential role in latent reservoir dynamics. The Journal of Experimental Medicine. PMID 28341641 DOI: 10.1084/Jem.20170193  0.602
2017 Lusic M, Siliciano RF. Corrigendum: Nuclear landscape of HIV-1 infection and integration. Nature Reviews. Microbiology. PMID 28239151 DOI: 10.1038/Nrmicro.2017.22  0.482
2017 Martin AR, Pollack RA, Capoferri A, Ambinder RF, Durand CM, Siliciano RF. Rapamycin-mediated mTOR inhibition uncouples HIV-1 latency reversal from cytokine-associated toxicity. The Journal of Clinical Investigation. PMID 28094770 DOI: 10.1172/Jci89552  0.669
2017 Gama L, Abreu CM, Shirk EN, Price SL, Li M, Laird GM, Pate KA, Wietgrefe SW, O'Connor SL, Pianowski L, Haase AT, Van Lint C, Siliciano RF, Clements JE. Reactivation of simian immunodeficiency virus reservoirs in the brain of virally suppressed macaques. Aids (London, England). 31: 5-14. PMID 27898590 DOI: 10.1097/Qad.0000000000001267  0.65
2017 Siliciano R. A-101 Defective proviruses rapidly accumulate during acute HIV-1 infection Jaids Journal of Acquired Immune Deficiency Syndromes. 74: 34. DOI: 10.1097/01.Qai.0000513811.12229.3E  0.584
2017 Capoferri A, Ramos JC, Xu D, Rosenbloom DIS, Siliciano JD, Siliciano RF, Noy A, Moore P, Ambinder RF, Durand CM. OA1-1 Impact of vorinostat treatment of non-Hodgkin‘s lymphoma on HIV-1 latent reservoir Journal of Virus Eradication. 3: 1. DOI: 10.1016/S2055-6640(20)30833-5  0.54
2017 Durand CM, Capoferri A, Redd AD, Rosenbloom DS, Gallant JE, Cash AE, Xu D, Ramirez R, Siliciano RF, Ambinder RF. 28 Optimised ART and alloBMT to reduce HIV reservoirs Journal of Virus Eradication. 3: 16-17. DOI: 10.1016/S2055-6640(20)30733-0  0.585
2017 Martin A, Durand C, Quinn T, Siliciano R, Redd A. Measurement and characterization of the latent reservoir for HIV-1 in patients receiving solid organ transplant Journal of Virus Eradication. 3: 22-23. DOI: 10.1016/S2055-6640(20)30606-3  0.474
2017 Murray AJ, Bruner KM, Kumar MR, Timmons AE, Liu P-, Clements JE, Barouch DH, Siliciano JD, Siliciano RF. SIV proviral landscape differs from that of HIV-1 and shows gross hypermutation Journal of Virus Eradication. 3: 13. DOI: 10.1016/S2055-6640(20)30586-0  0.6
2017 Bar KJ, Salantes B, Zheng Y, Mampe F, Beg S, Lai J, Tressler R, Koup R, Hoxie J, Mohsen MA, Siliciano R, Siliciano JM, Overton ET, Tebas P. Brief ATI does not alter the size or composition of the latent HIV-1 reservoir Journal of Virus Eradication. 3: 40-41. DOI: 10.1016/S2055-6640(20)30554-9  0.541
2017 Bertagnolli LN, White JA, Beg SA, Simonetti FR, Lai J, Tomescu C, Murray AJ, Antar AAR, Zhang Hao, Margolick JB, Montaner LJ, Siliciano RF, Laird GM, Siliciano JD. Majority of the latent reservoir resides in CD32a negative CD4+ T cells Journal of Virus Eradication. 3: 8. DOI: 10.1016/S2055-6640(20)30527-6  0.423
2017 Varabyou A, Talbot C, Zhang H, Beg S, Pollack R, Hao H, Margolick J, Siliciano RF, Pertea M, Ho Y-. HIV-1 proviruses which are integrated into cancer-related genes are inducible Journal of Virus Eradication. 3: 1. DOI: 10.1016/S2055-6640(20)30520-3  0.489
2016 Besnard E, Hakre S, Kampmann M, Lim HW, Hosmane NN, Martin A, Bassik MC, Verschueren E, Battivelli E, Chan J, Svensson JP, Gramatica A, Conrad RJ, Ott M, Greene WC, ... ... Siliciano RF, et al. The mTOR Complex Controls HIV Latency. Cell Host & Microbe. 20: 785-797. PMID 27978436 DOI: 10.1016/J.Chom.2016.11.001  0.637
2016 Lusic M, Siliciano RF. Nuclear landscape of HIV-1 infection and integration. Nature Reviews. Microbiology. PMID 27941817 DOI: 10.1038/Nrmicro.2016.162  0.61
2016 Laskey SB, Siliciano RF. Quantitative evaluation of the antiretroviral efficacy of dolutegravir. Jci Insight. 1: e90033. PMID 27882352 DOI: 10.1172/Jci.Insight.90033  0.59
2016 Gama L, Abreu CM, Shirk EN, Price SL, Li M, Laird GM, Pate KA, Wietgrefe SW, O'connor SL, Pianowski L, Haase AT, Van Lint C, Siliciano RF, Clements JE, Authors D, et al. Reactivation of SIV reservoirs in the brain of virally suppressed macaques. Aids (London, England). PMID 27662554 DOI: 10.1097/QAD.0000000000001267  0.564
2016 Hansen EC, Ransom M, Hesselberth JR, Hosmane NN, Capoferri AA, Bruner KM, Pollack RA, Zhang H, Drummond MB, Siliciano JM, Siliciano R, Stivers JT. Diverse fates of uracilated HIV-1 DNA during infection of myeloid lineage cells. Elife. 5. PMID 27644592 DOI: 10.7554/Elife.18447  0.595
2016 Hill AL, Rosenbloom DI, Siliciano JD, Siliciano RF. Insufficient Evidence for Rare Activation of Latent HIV in the Absence of Reservoir-Reducing Interventions. Plos Pathogens. 12: e1005679. PMID 27560936 DOI: 10.1371/Journal.Ppat.1005679  0.527
2016 Bruner KM, Murray AJ, Pollack RA, Soliman MG, Laskey SB, Capoferri AA, Lai J, Strain MC, Lada SM, Hoh R, Ho YC, Richman DD, Deeks SG, Siliciano JD, Siliciano RF. Defective proviruses rapidly accumulate during acute HIV-1 infection. Nature Medicine. PMID 27500724 DOI: 10.1038/Nm.4156  0.646
2016 Laskey SB, Pohlmeyer CW, Bruner KM, Siliciano RF. Evaluating Clonal Expansion of HIV-Infected Cells: Optimization of PCR Strategies to Predict Clonality. Plos Pathogens. 12: e1005689. PMID 27494508 DOI: 10.1371/Journal.Ppat.1005689  0.612
2016 Murray AJ, Kwon KJ, Farber DL, Siliciano RF. The Latent Reservoir for HIV-1: How Immunologic Memory and Clonal Expansion Contribute to HIV-1 Persistence. Journal of Immunology (Baltimore, Md. : 1950). 197: 407-17. PMID 27382129 DOI: 10.4049/Jimmunol.1600343  0.663
2016 Hill AL, Rosenbloom DI, Goldstein E, Hanhauser E, Kuritzkes DR, Siliciano RF, Henrich TJ. Real-Time Predictions of Reservoir Size and Rebound Time during Antiretroviral Therapy Interruption Trials for HIV. Plos Pathogens. 12: e1005535. PMID 27119536 DOI: 10.1016/S2055-6640(20)31327-3  0.542
2016 Kim M, Siliciano RF. Genome editing for clinical HIV isolates. Nature Biotechnology. 34: 388-389. PMID 27054991 DOI: 10.1038/Nbt.3531  0.594
2016 Sunshine S, Kirchner R, Amr SS, Mansur L, Shakhbatyan R, Kim M, Bosque A, Siliciano RF, Planelles V, Hofmann O, Ho Sui S, Li JZ. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. Journal of Virology. PMID 26912621 DOI: 10.1128/Jvi.01617-15  0.593
2016 Kim M, Siliciano RF. Reservoir expansion by T-cell proliferation may be another barrier to curing HIV infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 26862166 DOI: 10.1073/Pnas.1600097113  0.674
2016 Siliciano JD, Siliciano RF. Recent developments in the effort to cure HIV infection: going beyond N = 1. The Journal of Clinical Investigation. 126: 409-14. PMID 26829622 DOI: 10.1172/Jci86047  0.687
2016 Laird GM, Rosenbloom DI, Lai J, Siliciano RF, Siliciano JD. Measuring the Frequency of Latent HIV-1 in Resting CD4(+) T Cells Using a Limiting Dilution Coculture Assay. Methods in Molecular Biology (Clifton, N.J.). 1354: 239-53. PMID 26714716 DOI: 10.1007/978-1-4939-3046-3_16  0.716
2016 Hansen EC, Ransom M, Hesselberth JR, Hosmane NN, Capoferri AA, Bruner KM, Pollack RA, Zhang H, Drummond MB, Siliciano JM, Siliciano R, Stivers JT. Author response: Diverse fates of uracilated HIV-1 DNA during infection of myeloid lineage cells Elife. DOI: 10.7554/Elife.18447.030  0.575
2016 Siliciano R. B-101 Unique features of effector to memory transition render CD4+ T cells permissive for latent HIV infection Jaids Journal of Acquired Immune Deficiency Syndromes. 71: 40. DOI: 10.1097/01.Qai.0000479586.53001.6E  0.581
2016 Prodger JL, Siliciano JD, Lai J, Reynolds SJ, Kasule J, Kityamuweesi T, Serwadda D, Redd AD, Siliciano RF, Moore RD, Quinn TC. 19 Quantification and correlates of the replication competent HIV-1 latent viral reservoir in a virally suppressed Ugandan population Journal of Virus Eradication. 2: 15. DOI: 10.1016/S2055-6640(20)30964-X  0.588
2015 Churchill MJ, Deeks SG, Margolis DM, Siliciano RF, Swanstrom R. HIV reservoirs: what, where and how to target them. Nature Reviews. Microbiology. PMID 26616417 DOI: 10.1038/Nrmicro.2015.5  0.585
2015 Martin AR, Siliciano RF. Progress Toward HIV Eradication: Case Reports, Current Efforts, and the Challenges Associated with Cure. Annual Review of Medicine. PMID 26526767 DOI: 10.1146/Annurev-Med-011514-023043  0.574
2015 Gray WT, Frey KM, Laskey SB, Mislak AC, Spasov KA, Lee WG, Bollini M, Siliciano RF, Jorgensen WL, Anderson KS. Potent Inhibitors Active against HIV Reverse Transcriptase with K101P, a Mutation Conferring Rilpivirine Resistance. Acs Medicinal Chemistry Letters. 6: 1075-9. PMID 26487915 DOI: 10.1021/Acsmedchemlett.5B00254  0.488
2015 Rosenbloom DI, Elliott O, Hill AL, Henrich TJ, Siliciano JM, Siliciano RF. Designing and Interpreting Limiting Dilution Assays: General Principles and Applications to the Latent Reservoir for Human Immunodeficiency Virus-1. Open Forum Infectious Diseases. 2: ofv123. PMID 26478893 DOI: 10.1093/Ofid/Ofv123  0.516
2015 Sampah ME, Laird GM, Blankson JN, Siliciano RF, Coleman JS. Medroxyprogesterone acetate increases HIV-1 infection of unstimulated peripheral blood mononuclear cells in vitro. Aids (London, England). 29: 1137-46. PMID 26035316 DOI: 10.1097/Qad.0000000000000681  0.858
2015 Siliciano JM, Siliciano RF. The Remarkable Stability of the Latent Reservoir for HIV-1 in Resting Memory CD4+ T Cells. The Journal of Infectious Diseases. 212: 1345-7. PMID 25877551 DOI: 10.1093/Infdis/Jiv219  0.578
2015 Laird GM, Bullen CK, Rosenbloom DI, Martin AR, Hill AL, Durand CM, Siliciano JD, Siliciano RF. Ex vivo analysis identifies effective HIV-1 latency-reversing drug combinations. The Journal of Clinical Investigation. 125: 1901-12. PMID 25822022 DOI: 10.1172/Jci80142  0.646
2015 Bruner KM, Hosmane NN, Siliciano RF. Towards an HIV-1 cure: measuring the latent reservoir. Trends in Microbiology. 23: 192-203. PMID 25747663 DOI: 10.1016/J.Tim.2015.01.013  0.613
2015 Cohn LB, Silva IT, Oliveira TY, Rosales RA, Parrish EH, Learn GH, Hahn BH, Czartoski JL, McElrath MJ, Lehmann C, Klein F, Caskey M, Walker BD, Siliciano JD, Siliciano RF, et al. HIV-1 integration landscape during latent and active infection. Cell. 160: 420-32. PMID 25635456 DOI: 10.1016/J.Cell.2015.01.020  0.645
2015 Deng K, Pertea M, Rongvaux A, Wang L, Durand CM, Ghiaur G, Lai J, McHugh HL, Hao H, Zhang H, Margolick JB, Gurer C, Murphy AJ, Valenzuela DM, Yancopoulos GD, ... ... Siliciano RF, et al. Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations. Nature. 517: 381-5. PMID 25561180 DOI: 10.1038/Nature14053  0.82
2015 Cash A, Capoferri A, Xu D, Mchugh H, Laeyendecker O, Sakoian S, Tony L, Bullen C, Pohlmeyer C, Pham P, Lai J, Gallant J, Siliciano R, Flexner C, Pratz K, et al. Safety of Optimized Antiretroviral Therapy During Allogeneic Matched and Haploidentical Bone Marrow Transplant in HIV+ Individuals Open Forum Infectious Diseases. 2. DOI: 10.1093/Ofid/Ofv131.83  0.428
2014 Deeks SG, Siliciano R. HIV Prevention and Treatment Fields Join Forces. Ebiomedicine. 1: 4-5. PMID 26137503 DOI: 10.1016/J.Ebiom.2014.10.009  0.635
2014 Zarr M, Siliciano R. Stoichiometric parameters of HIV-1 entry. Virology. 474: 1-9. PMID 25463598 DOI: 10.1016/J.Virol.2014.10.007  0.655
2014 Kim M, Hosmane NN, Bullen CK, Capoferri A, Yang HC, Siliciano JD, Siliciano RF. A primary CD4(+) T cell model of HIV-1 latency established after activation through the T cell receptor and subsequent return to quiescence. Nature Protocols. 9: 2755-70. PMID 25375990 DOI: 10.1038/Nprot.2014.188  0.77
2014 Cockerham LR, Siliciano JD, Sinclair E, O'Doherty U, Palmer S, Yukl SA, Strain MC, Chomont N, Hecht FM, Siliciano RF, Richman DD, Deeks SG. CD4+ and CD8+ T cell activation are associated with HIV DNA in resting CD4+ T cells. Plos One. 9: e110731. PMID 25340755 DOI: 10.1371/Journal.Pone.0110731  0.652
2014 Blankson JN, Siliciano JD, Siliciano RF. Finding a cure for human immunodeficiency virus-1 infection. Infectious Disease Clinics of North America. 28: 633-50. PMID 25277513 DOI: 10.1016/J.Idc.2014.08.007  0.626
2014 Laskey SB, Siliciano RF. A mechanistic theory to explain the efficacy of antiretroviral therapy. Nature Reviews. Microbiology. 12: 772-80. PMID 25263222 DOI: 10.1038/Nrmicro3351  0.548
2014 Siliciano JD, Siliciano RF. AIDS/HIV. Rekindled HIV infection. Science (New York, N.Y.). 345: 1005-6. PMID 25170139 DOI: 10.1126/Science.1259452  0.622
2014 Siliciano JD, Siliciano RF. Recent developments in the search for a cure for HIV-1 infection: targeting the latent reservoir for HIV-1. The Journal of Allergy and Clinical Immunology. 134: 12-9. PMID 25117799 DOI: 10.1016/J.Jaci.2014.05.026  0.664
2014 Hill AL, Rosenbloom DI, Fu F, Nowak MA, Siliciano RF. Predicting the outcomes of treatment to eradicate the latent reservoir for HIV-1. Proceedings of the National Academy of Sciences of the United States of America. 111: 13475-80. PMID 25097264 DOI: 10.1073/Pnas.1406663111  0.545
2014 Deng K, Siliciano RF. HIV: Early treatment may not be early enough. Nature. 512: 35-6. PMID 25043038 DOI: 10.1038/Nature13647  0.566
2014 Dar RD, Hosmane NN, Arkin MR, Siliciano RF, Weinberger LS. Screening for noise in gene expression identifies drug synergies. Science (New York, N.Y.). 344: 1392-6. PMID 24903562 DOI: 10.1126/Science.1250220  0.393
2014 Shan L, Siliciano RF. Unraveling the relationship between microbial translocation and systemic immune activation in HIV infection. The Journal of Clinical Investigation. 124: 2368-71. PMID 24837427 DOI: 10.1172/Jci75799  0.709
2014 Siliciano RF. Opening Fronts in HIV Vaccine Development: Targeting reservoirs to clear and cure. Nature Medicine. 20: 480-1. PMID 24804757 DOI: 10.1038/Nm.3550  0.467
2014 Ho YC, Laird GM, Siliciano RF. Measuring reversal of HIV-1 latency ex vivo using cells from infected individuals. Proceedings of the National Academy of Sciences of the United States of America. 111: 6860-1. PMID 24799684 DOI: 10.1073/Pnas.1405194111  0.671
2014 Bullen CK, Laird GM, Durand CM, Siliciano JD, Siliciano RF. New ex vivo approaches distinguish effective and ineffective single agents for reversing HIV-1 latency in vivo. Nature Medicine. 20: 425-9. PMID 24658076 DOI: 10.1038/Nm.3489  0.666
2014 Cox AL, Siliciano RF. HIV: Not-so-innocent bystanders. Nature. 505: 492-3. PMID 24451540 DOI: 10.1038/505492A  0.666
2014 Salgado M, Swanson MD, Pohlmeyer CW, Buckheit RW, Wu J, Archin NM, Williams TM, Margolis DM, Siliciano RF, Garcia JV, Blankson JN. HLA-B*57 elite suppressor and chronic progressor HIV-1 isolates replicate vigorously and cause CD4+ T cell depletion in humanized BLT mice. Journal of Virology. 88: 3340-52. PMID 24390323 DOI: 10.1128/Jvi.03380-13  0.611
2014 Durand CM, Siliciano RF. Dual zinc-finger nucleases block HIV infection. Blood. 123: 2-3. PMID 24385492 DOI: 10.1182/Blood-2013-11-535542  0.586
2014 Spivak AM, Andrade A, Eisele E, Hoh R, Bacchetti P, Bumpus NN, Emad F, Buckheit R, McCance-Katz EF, Lai J, Kennedy M, Chander G, Siliciano RF, Siliciano JD, Deeks SG. A pilot study assessing the safety and latency-reversing activity of disulfiram in HIV-1-infected adults on antiretroviral therapy. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 58: 883-90. PMID 24336828 DOI: 10.1093/Cid/Cit813  0.686
2014 Laird GM, Eisele EE, Rabi SA, Nikolaeva D, Siliciano RF. A novel cell-based high-throughput screen for inhibitors of HIV-1 gene expression and budding identifies the cardiac glycosides. The Journal of Antimicrobial Chemotherapy. 69: 988-94. PMID 24275119 DOI: 10.1093/Jac/Dkt471  0.517
2014 Shan L, Xing S, Yang HC, Zhang H, Margolick JB, Siliciano RF. Unique characteristics of histone deacetylase inhibitors in reactivation of latent HIV-1 in Bcl-2-transduced primary resting CD4+ T cells. The Journal of Antimicrobial Chemotherapy. 69: 28-33. PMID 23999005 DOI: 10.1093/Jac/Dkt338  0.867
2014 Hill AL, Rosenbloom DIS, Fu F, Nowak MA, Siliciano RF. Corrections: Predicting the outcomes of treatment to eradicate the latent reservoir for HIV-1 (Proc Natl Acad Sci USA (2014) 111, (13475-13480) doi: 10.1073/pnas.1406663111) Proceedings of the National Academy of Sciences of the United States of America. 111: 15598. DOI: 10.1073/Pnas.1418638111  0.489
2013 Spina CA, Anderson J, Archin NM, Bosque A, Chan J, Famiglietti M, Greene WC, Kashuba A, Lewin SR, Margolis DM, Mau M, Ruelas D, Saleh S, Shirakawa K, Siliciano RF, et al. An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patients. Plos Pathogens. 9: e1003834. PMID 24385908 DOI: 10.1371/Journal.Ppat.1003834  0.748
2013 Cox AL, Siliciano RF. Making sense of HIV innate sensing. Immunity. 39: 998-1000. PMID 24332027 DOI: 10.1016/J.Immuni.2013.11.014  0.58
2013 Pohlmeyer CW, Buckheit RW, Siliciano RF, Blankson JN. CD8+ T cells from HLA-B*57 elite suppressors effectively suppress replication of HIV-1 escape mutants. Retrovirology. 10: 152. PMID 24330837 DOI: 10.1186/1742-4690-10-152  0.65
2013 Chen I, Khaki L, Lindsey JC, Fry C, Cousins MM, Siliciano RF, Violari A, Palumbo P, Eshleman SH. Association of pol diversity with antiretroviral treatment outcomes among HIV-infected African children. Plos One. 8: e81213. PMID 24312277 DOI: 10.1371/Journal.Pone.0081213  0.509
2013 Ho YC, Shan L, Hosmane NN, Wang J, Laskey SB, Rosenbloom DI, Lai J, Blankson JN, Siliciano JD, Siliciano RF. Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure. Cell. 155: 540-51. PMID 24243014 DOI: 10.1016/J.Cell.2013.09.020  0.724
2013 Dobrowsky TM, Rabi SA, Nedellec R, Daniels BR, Mullins JI, Mosier DE, Siliciano RF, Wirtz D. Adhesion and fusion efficiencies of human immunodeficiency virus type 1 (HIV-1) surface proteins. Scientific Reports. 3: 3014. PMID 24145278 DOI: 10.1038/Srep03014  0.596
2013 Siliciano JD, Siliciano RF. Recent trends in HIV-1 drug resistance. Current Opinion in Virology. 3: 487-94. PMID 24021560 DOI: 10.1016/J.Coviro.2013.08.007  0.52
2013 Rabi SA, Laird GM, Durand CM, Laskey S, Shan L, Bailey JR, Chioma S, Moore RD, Siliciano RF. Multi-step inhibition explains HIV-1 protease inhibitor pharmacodynamics and resistance. The Journal of Clinical Investigation. 123: 3848-60. PMID 23979165 DOI: 10.1172/Jci67399  0.729
2013 Sherrill-Mix S, Lewinski MK, Famiglietti M, Bosque A, Malani N, Ocwieja KE, Berry CC, Looney D, Shan L, Agosto LM, Pace MJ, Siliciano RF, O'Doherty U, Guatelli J, Planelles V, et al. HIV latency and integration site placement in five cell-based models. Retrovirology. 10: 90. PMID 23953889 DOI: 10.1186/1742-4690-10-90  0.675
2013 Shen A, Baker JJ, Scott GL, Davis YP, Ho YY, Siliciano RF. Endothelial cell stimulation overcomes restriction and promotes productive and latent HIV-1 infection of resting CD4+ T cells. Journal of Virology. 87: 9768-79. PMID 23824795 DOI: 10.1128/Jvi.01478-13  0.753
2013 Buckheit RW, Siliciano RF, Blankson JN. Primary CD8+ T cells from elite suppressors effectively eliminate non-productively HIV-1 infected resting and activated CD4+ T cells. Retrovirology. 10: 68. PMID 23816179 DOI: 10.1186/1742-4690-10-68  0.645
2013 Laird GM, Eisele EE, Rabi SA, Lai J, Chioma S, Blankson JN, Siliciano JD, Siliciano RF. Rapid quantification of the latent reservoir for HIV-1 using a viral outgrowth assay. Plos Pathogens. 9: e1003398. PMID 23737751 DOI: 10.1371/Journal.Ppat.1003398  0.689
2013 Siliciano JD, Siliciano RF. HIV-1 eradication strategies: design and assessment. Current Opinion in Hiv and Aids. 8: 318-25. PMID 23698561 DOI: 10.1097/Coh.0B013E328361Eaca  0.578
2013 Yukl SA, Boritz E, Busch M, Bentsen C, Chun TW, Douek D, Eisele E, Haase A, Ho YC, Hütter G, Justement JS, Keating S, Lee TH, Li P, Murray D, ... ... Siliciano R, et al. Challenges in detecting HIV persistence during potentially curative interventions: a study of the Berlin patient. Plos Pathogens. 9: e1003347. PMID 23671416 DOI: 10.1371/Journal.Ppat.1003347  0.622
2013 Shan L, Siliciano RF. From reactivation of latent HIV-1 to elimination of the latent reservoir: the presence of multiple barriers to viral eradication. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 35: 544-52. PMID 23613347 DOI: 10.1002/Bies.201200170  0.788
2013 Avery LB, Zarr MA, Bakshi RP, Siliciano RF, Hendrix CW. Increasing extracellular protein concentration reduces intracellular antiretroviral drug concentration and antiviral effect. Aids Research and Human Retroviruses. 29: 1434-42. PMID 23601085 DOI: 10.1089/Aid.2013.0031  0.476
2013 Shan L, Rabi SA, Laird GM, Eisele EE, Zhang H, Margolick JB, Siliciano RF. A novel PCR assay for quantification of HIV-1 RNA. Journal of Virology. 87: 6521-5. PMID 23536672 DOI: 10.1128/Jvi.00006-13  0.742
2013 Eriksson S, Graf EH, Dahl V, Strain MC, Yukl SA, Lysenko ES, Bosch RJ, Lai J, Chioma S, Emad F, Abdel-Mohsen M, Hoh R, Hecht F, Hunt P, Somsouk M, ... ... Siliciano RF, et al. Comparative analysis of measures of viral reservoirs in HIV-1 eradication studies. Plos Pathogens. 9: e1003174. PMID 23459007 DOI: 10.1371/Journal.Ppat.1003174  0.676
2013 Gandhi RT, Bosch RJ, Aga E, Bedison MA, Bastow B, Schmitz JL, Siliciano JD, Siliciano RF, Eron JJ, Mellors JW. Residual plasma viraemia and infectious HIV-1 recovery from resting memory CD4 cells in patients on antiretroviral therapy: results from ACTG A5173. Antiviral Therapy. 18: 607-13. PMID 23411421 DOI: 10.3851/Imp2543  0.644
2013 Weil AF, Ghosh D, Zhou Y, Seiple L, McMahon MA, Spivak AM, Siliciano RF, Stivers JT. Uracil DNA glycosylase initiates degradation of HIV-1 cDNA containing misincorporated dUTP and prevents viral integration. Proceedings of the National Academy of Sciences of the United States of America. 110: E448-57. PMID 23341616 DOI: 10.1073/Pnas.1219702110  0.737
2013 Xing S, Siliciano RF. Targeting HIV latency: pharmacologic strategies toward eradication. Drug Discovery Today. 18: 541-51. PMID 23270785 DOI: 10.1016/J.Drudis.2012.12.008  0.728
2013 Boehm D, Calvanese V, Dar RD, Xing S, Schroeder S, Martins L, Aull K, Li PC, Planelles V, Bradner JE, Zhou MM, Siliciano RF, Weinberger L, Verdin E, Ott M. BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism. Cell Cycle (Georgetown, Tex.). 12: 452-62. PMID 23255218 DOI: 10.4161/Cc.23309  0.753
2013 Chen I, Khaki L, Lindsey JC, Fry C, Cousins MM, Siliciano RF, Violari A, Palumbo P, Eshleman SH. Correction: Association of pol Diversity with Antiretroviral Treatment Outcomes among HIV-Infected African Children Plos One. 8. DOI: 10.1371/annotation/dd945f7c-c50b-461d-ab38-15e8b0966458  0.43
2013 Chen I, Khaki L, Lindsey JC, Fry C, Cousins MM, Siliciano RF, Violari A, Palumbo P, Eshleman SH. Correction: Association of pol Diversity with Antiretroviral Atment Outcomes among HIV-Infected African Children Plos One. 8. DOI: 10.1371/annotation/6937ccda-2f54-430d-94d0-b71d1ecc5273  0.439
2012 Zinchenko MK, Siliciano RF. Editorial: JQ1: giving HIV-1 expression a boost by blocking bromodomains? Journal of Leukocyte Biology. 92: 1127-9. PMID 23204259 DOI: 10.1189/Jlb.0712358  0.703
2012 Eisele E, Siliciano RF. Redefining the viral reservoirs that prevent HIV-1 eradication. Immunity. 37: 377-88. PMID 22999944 DOI: 10.1016/J.Immuni.2012.08.010  0.647
2012 Rosenbloom DI, Hill AL, Rabi SA, Siliciano RF, Nowak MA. Antiretroviral dynamics determines HIV evolution and predicts therapy outcome. Nature Medicine. 18: 1378-85. PMID 22941277 DOI: 10.1038/Nm.2892  0.508
2012 Deng K, Zink MC, Clements JE, Siliciano RF. A quantitative measurement of antiviral activity of anti-human immunodeficiency virus type 1 drugs against simian immunodeficiency virus infection: dose-response curve slope strongly influences class-specific inhibitory potential. Journal of Virology. 86: 11368-72. PMID 22875968 DOI: 10.1128/Jvi.01563-12  0.552
2012 Durand CM, Blankson JN, Siliciano RF. Developing strategies for HIV-1 eradication. Trends in Immunology. 33: 554-62. PMID 22867874 DOI: 10.1016/J.It.2012.07.001  0.695
2012 Thayil SM, Ho YC, Bollinger RC, Blankson JN, Siliciano RF, Karakousis PC, Page KR. Mycobacterium tuberculosis complex enhances susceptibility of CD4 T cells to HIV through a TLR2-mediated pathway. Plos One. 7: e41093. PMID 22844428 DOI: 10.1371/Journal.Pone.0041093  0.573
2012 Goldberg DE, Siliciano RF, Jacobs WR. Outwitting evolution: fighting drug-resistant TB, malaria, and HIV. Cell. 148: 1271-83. PMID 22424234 DOI: 10.1016/J.Cell.2012.02.021  0.46
2012 Shan L, Deng K, Shroff NS, Durand CM, Rabi SA, Yang HC, Zhang H, Margolick JB, Blankson JN, Siliciano RF. Stimulation of HIV-1-specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation. Immunity. 36: 491-501. PMID 22406268 DOI: 10.1016/J.Immuni.2012.01.014  0.862
2012 Buckheit RW, Allen TG, Alme A, Salgado M, O'Connell KA, Huculak S, Falade-Nwulia O, Williams TM, Gallant JE, Siliciano RF, Blankson JN. Host factors dictate control of viral replication in two HIV-1 controller/chronic progressor transmission pairs. Nature Communications. 3: 716. PMID 22395607 DOI: 10.1038/Ncomms1697  0.742
2012 Jilek BL, Zarr M, Sampah ME, Rabi SA, Bullen CK, Lai J, Shen L, Siliciano RF. A quantitative basis for antiretroviral therapy for HIV-1 infection. Nature Medicine. 18: 446-51. PMID 22344296 DOI: 10.1038/Nm.2649  0.829
2012 Durand CM, Ghiaur G, Siliciano JD, Rabi SA, Eisele EE, Salgado M, Shan L, Lai JF, Zhang H, Margolick J, Jones RJ, Gallant JE, Ambinder RF, Siliciano RF. HIV-1 DNA is detected in bone marrow populations containing CD4+ T cells but is not found in purified CD34+ hematopoietic progenitor cells in most patients on antiretroviral therapy. The Journal of Infectious Diseases. 205: 1014-8. PMID 22275402 DOI: 10.1093/Infdis/Jir884  0.797
2012 Xing S, Bhat S, Shroff NS, Zhang H, Lopez JA, Margolick JB, Liu JO, Siliciano RF. Novel structurally related compounds reactivate latent HIV-1 in a bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation. The Journal of Antimicrobial Chemotherapy. 67: 398-403. PMID 22160146 DOI: 10.1093/Jac/Dkr496  0.802
2012 Sampah ME, Jilek B, Shen L, Rabi A, Zarr M, Bullen CK, Lai J, Siliciano R. Quantifying combination ARV drug effects in wild type and resistant HIV-1 infection F1000research. 3. DOI: 10.7490/F1000Research.1089961.1  0.852
2011 Siliciano RF, Greene WC. HIV latency. Cold Spring Harbor Perspectives in Medicine. 1: a007096. PMID 22229121 DOI: 10.1101/cshperspect.a007096  0.646
2011 Salgado M, Rabi SA, O'Connell KA, Buckheit RW, Bailey JR, Chaudhry AA, Breaud AR, Marzinke MA, Clarke W, Margolick JB, Siliciano RF, Blankson JN. Prolonged control of replication-competent dual- tropic human immunodeficiency virus-1 following cessation of highly active antiretroviral therapy. Retrovirology. 8: 97. PMID 22141397 DOI: 10.1186/1742-4690-8-97  0.855
2011 Siliciano RF. Measurement of antiviral activity in drugs for HIV-1. The Lancet. Infectious Diseases. 11: 888-9. PMID 21933753 DOI: 10.1016/S1473-3099(11)70250-X  0.565
2011 O'Connell KA, Rabi SA, Siliciano RF, Blankson JN. CD4+ T cells from elite suppressors are more susceptible to HIV-1 but produce fewer virions than cells from chronic progressors. Proceedings of the National Academy of Sciences of the United States of America. 108: E689-98. PMID 21873218 DOI: 10.1073/Pnas.1108866108  0.772
2011 O'Connell KA, Hegarty RW, Siliciano RF, Blankson JN. Viral suppression of multiple escape mutants by de novo CD8(+) T cell responses in a human immunodeficiency virus-1 infected elite suppressor. Retrovirology. 8: 63. PMID 21812985 DOI: 10.1186/1742-4690-8-63  0.735
2011 Shen L, Rabi SA, Sedaghat AR, Shan L, Lai J, Xing S, Siliciano RF. A critical subset model provides a conceptual basis for the high antiviral activity of major HIV drugs. Science Translational Medicine. 3: 91ra63. PMID 21753122 DOI: 10.1126/Scitranslmed.3002304  0.799
2011 Sampah ME, Shen L, Jilek BL, Siliciano RF. Dose-response curve slope is a missing dimension in the analysis of HIV-1 drug resistance. Proceedings of the National Academy of Sciences of the United States of America. 108: 7613-8. PMID 21502494 DOI: 10.1073/Pnas.1018360108  0.798
2011 Xing S, Bullen CK, Shroff NS, Shan L, Yang HC, Manucci JL, Bhat S, Zhang H, Margolick JB, Quinn TC, Margolis DM, Siliciano JD, Siliciano RF. Disulfiram reactivates latent HIV-1 in a Bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation. Journal of Virology. 85: 6060-4. PMID 21471244 DOI: 10.1128/Jvi.02033-10  0.876
2011 Shan L, Yang HC, Rabi SA, Bravo HC, Shroff NS, Irizarry RA, Zhang H, Margolick JB, Siliciano JD, Siliciano RF. Influence of host gene transcription level and orientation on HIV-1 latency in a primary-cell model. Journal of Virology. 85: 5384-93. PMID 21430059 DOI: 10.1128/Jvi.02536-10  0.85
2011 McMahon MA, Parsons TL, Shen L, Siliciano JD, Siliciano RF. Consistent inhibition of HIV-1 replication in CD4+ T cells by acyclovir without detection of human herpesviruses. Journal of Virology. 85: 4618-22. PMID 21325417 DOI: 10.1128/Jvi.02423-10  0.83
2011 Spivak AM, Rabi SA, McMahon MA, Shan L, Sedaghat AR, Wilke CO, Siliciano RF. Short communication: dynamic constraints on the second phase compartment of HIV-infected cells. Aids Research and Human Retroviruses. 27: 759-61. PMID 21105850 DOI: 10.1089/Aid.2010.0199  0.84
2011 Rabi SA, O'Connell KA, Nikolaeva D, Bailey JR, Jilek BL, Shen L, Page KR, Siliciano RF, Blankson JN. Unstimulated primary CD4+ T cells from HIV-1-positive elite suppressors are fully susceptible to HIV-1 entry and productive infection. Journal of Virology. 85: 979-86. PMID 21068257 DOI: 10.1128/Jvi.01721-10  0.887
2011 Blankson JN, Siliciano RF. Immunopathogenesis of Human Immunodeficiency Virus Infection Goldman's Cecil Medicine: Twenty Fourth Edition. 2: 2175-2177. DOI: 10.1016/B978-1-4377-1604-7.00393-6  0.451
2010 Bellows ML, Taylor MS, Cole PA, Shen L, Siliciano RF, Fung HK, Floudas CA. Discovery of entry inhibitors for HIV-1 via a new de novo protein design framework. Biophysical Journal. 99: 3445-53. PMID 21081094 DOI: 10.1016/J.Bpj.2010.09.050  0.512
2010 Salgado M, Brennan TP, O'Connell KA, Bailey JR, Ray SC, Siliciano RF, Blankson JN. Evolution of the HIV-1 nef gene in HLA-B*57 positive elite suppressors. Retrovirology. 7: 94. PMID 21059238 DOI: 10.1186/1742-4690-7-94  0.782
2010 Siliciano JD, Siliciano RF. Biomarkers of HIV replication. Current Opinion in Hiv and Aids. 5: 491-7. PMID 20978392 DOI: 10.1097/Coh.0B013E32833F206F  0.565
2010 Kohli RM, Maul RW, Guminski AF, McClure RL, Gajula KS, Saribasak H, McMahon MA, Siliciano RF, Gearhart PJ, Stivers JT. Local sequence targeting in the AID/APOBEC family differentially impacts retroviral restriction and antibody diversification. The Journal of Biological Chemistry. 285: 40956-64. PMID 20929867 DOI: 10.1074/Jbc.M110.177402  0.667
2010 Shen L, Siliciano RF. Achieving a quantitative understanding of antiretroviral drug efficacy. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 51: 1105-6; author reply. PMID 20925507 DOI: 10.1086/656688  0.494
2010 Siliciano RF. What do we need to do to cure HIV infection. Topics in Hiv Medicine : a Publication of the International Aids Society, Usa. 18: 104-8. PMID 20921575  0.573
2010 Dobrowsky TM, Daniels BR, Siliciano RF, Sun SX, Wirtz D. Organization of cellular receptors into a nanoscale junction during HIV-1 adhesion. Plos Computational Biology. 6: e1000855. PMID 20657663 DOI: 10.1371/Journal.Pcbi.1000855  0.517
2010 Kim HN, Wang J, Hughes J, Coombs R, Sanchez J, Reid S, Delany-Moretlwe S, Cowan F, Fuchs J, Eshleman SH, Khaki L, McMahon MA, Siliciano RF, Wald A, Celum C. Effect of acyclovir on HIV-1 set point among herpes simplex virus type 2-seropositive persons during early HIV-1 infection. The Journal of Infectious Diseases. 202: 734-8. PMID 20649426 DOI: 10.1086/655662  0.817
2010 Spivak AM, Siliciano RF. Using highly active antiretroviral therapy to decrease perioperative HIV-1 transmission risk. Aids (London, England). 24: 1603-4; author reply. PMID 20539094 DOI: 10.1097/Qad.0B013E32832F3155  0.6
2010 O'Connell KA, Brennan TP, Bailey JR, Ray SC, Siliciano RF, Blankson JN. Control of HIV-1 in elite suppressors despite ongoing replication and evolution in plasma virus. Journal of Virology. 84: 7018-28. PMID 20444904 DOI: 10.1128/Jvi.00548-10  0.784
2010 Szeto GL, Brice AK, Yang HC, Barber SA, Siliciano RF, Clements JE. Minocycline attenuates HIV infection and reactivation by suppressing cellular activation in human CD4+ T cells. The Journal of Infectious Diseases. 201: 1132-40. PMID 20205570 DOI: 10.1086/651277  0.801
2010 Spivak AM, Brennan TP, O'Connell KA, Sydnor E, Williams TM, Siliciano RF, Gallant JE, Blankson JN. A case of seronegative HIV-1 infection. The Journal of Infectious Diseases. 201: 341-5. PMID 20039801 DOI: 10.1086/649822  0.786
2010 McMahon MA, Siliciano JD, Kohli RM, Siliciano RF. Sensitivity of V75I HIV-1 reverse transcriptase mutant selected in vitro by acyclovir to anti-HIV drugs. Aids (London, England). 24: 319-23. PMID 20009920 DOI: 10.1097/Qad.0B013E32833424E5  0.815
2010 Gandhi RT, Bosch RJ, Aga E, Albrecht M, Demeter LM, Dykes C, Bastow B, Para M, Lai J, Siliciano RF, Siliciano JD, Eron JJ. No evidence for decay of the latent reservoir in HIV-1-infected patients receiving intensive enfuvirtide-containing antiretroviral therapy. The Journal of Infectious Diseases. 201: 293-6. PMID 20001856 DOI: 10.1086/649569  0.595
2009 O'Connell KA, Xu J, Durbin AP, Apuzzo LG, Imteyaz H, Williams TM, Ray SC, Margolick JB, Siliciano RF, Blankson JN. HIV-1 evolution following transmission to an HLA-B*5801-positive patient. The Journal of Infectious Diseases. 200: 1820-4. PMID 19909081 DOI: 10.1086/648377  0.721
2009 McMahon MA, Shen L, Siliciano RF. New approaches for quantitating the inhibition of HIV-1 replication by antiviral drugs in vitro and in vivo. Current Opinion in Infectious Diseases. 22: 574-82. PMID 19841584 DOI: 10.1097/Qco.0B013E328332C54D  0.801
2009 Shen L, Rabi SA, Siliciano RF. A novel method for determining the inhibitory potential of anti-HIV drugs. Trends in Pharmacological Sciences. 30: 610-6. PMID 19837466 DOI: 10.1016/J.Tips.2009.09.003  0.62
2009 Yang HC, Xing S, Shan L, O'Connell K, Dinoso J, Shen A, Zhou Y, Shrum CK, Han Y, Liu JO, Zhang H, Margolick JB, Siliciano RF. Small-molecule screening using a human primary cell model of HIV latency identifies compounds that reverse latency without cellular activation. The Journal of Clinical Investigation. 119: 3473-86. PMID 19805909 DOI: 10.1172/Jci39199  0.886
2009 Dinoso JB, Rabi SA, Blankson JN, Gama L, Mankowski JL, Siliciano RF, Zink MC, Clements JE. A simian immunodeficiency virus-infected macaque model to study viral reservoirs that persist during highly active antiretroviral therapy. Journal of Virology. 83: 9247-57. PMID 19570871 DOI: 10.1128/Jvi.00840-09  0.879
2009 Brennan TP, Woods JO, Sedaghat AR, Siliciano JD, Siliciano RF, Wilke CO. Analysis of human immunodeficiency virus type 1 viremia and provirus in resting CD4+ T cells reveals a novel source of residual viremia in patients on antiretroviral therapy. Journal of Virology. 83: 8470-81. PMID 19535437 DOI: 10.1128/Jvi.02568-08  0.742
2009 Dinoso JB, Kim SY, Wiegand AM, Palmer SE, Gange SJ, Cranmer L, O'Shea A, Callender M, Spivak A, Brennan T, Kearney MF, Proschan MA, Mican JM, Rehm CA, Coffin JM, ... ... Siliciano RF, et al. Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy. Proceedings of the National Academy of Sciences of the United States of America. 106: 9403-8. PMID 19470482 DOI: 10.1073/Pnas.0903107106  0.871
2009 Sedaghat AR, Siliciano RF, Wilke CO. Constraints on the dominant mechanism for HIV viral dynamics in patients on raltegravir. Antiviral Therapy. 14: 263-71. PMID 19430101  0.707
2009 Lassen KG, Lobritz MA, Bailey JR, Johnston S, Nguyen S, Lee B, Chou T, Siliciano RF, Markowitz M, Arts EJ. Elite suppressor-derived HIV-1 envelope glycoproteins exhibit reduced entry efficiency and kinetics. Plos Pathogens. 5: e1000377. PMID 19360131 DOI: 10.1371/Journal.Ppat.1000377  0.861
2009 Wind-Rotolo M, Durand C, Cranmer L, Reid A, Martinson N, Doherty M, Jilek BL, Kagaayi J, Kizza A, Pillay V, Laeyendecker O, Reynolds SJ, Eshleman SH, Lau B, Ray SC, ... ... Siliciano RF, et al. Identification of nevirapine-resistant HIV-1 in the latent reservoir after single-dose nevirapine to prevent mother-to-child transmission of HIV-1. The Journal of Infectious Diseases. 199: 1301-9. PMID 19338474 DOI: 10.1086/597759  0.869
2009 Yang HC, Shen L, Siliciano RF, Pomerantz JL. Isolation of a cellular factor that can reactivate latent HIV-1 without T cell activation. Proceedings of the National Academy of Sciences of the United States of America. 106: 6321-6. PMID 19336585 DOI: 10.1073/Pnas.0809536106  0.799
2009 O'Connell KA, Han Y, Williams TM, Siliciano RF, Blankson JN. Role of natural killer cells in a cohort of elite suppressors: low frequency of the protective KIR3DS1 allele and limited inhibition of human immunodeficiency virus type 1 replication in vitro. Journal of Virology. 83: 5028-34. PMID 19211742 DOI: 10.1128/Jvi.02551-08  0.832
2009 Bailey JR, Brennan TP, O'Connell KA, Siliciano RF, Blankson JN. Evidence of CD8+ T-cell-mediated selective pressure on human immunodeficiency virus type 1 nef in HLA-B*57+ elite suppressors. Journal of Virology. 83: 88-97. PMID 18945771 DOI: 10.1128/Jvi.01958-08  0.811
2008 Blankson JN, Siliciano RF. Elite suppression of HIV-1 replication. Immunity. 29: 845-7. PMID 19100698 DOI: 10.1016/J.Immuni.2008.12.002  0.681
2008 O'Connell K, Siliciano RF. Immune alteration fends off AIDS. Nature Medicine. 14: 1016-8. PMID 18841135 DOI: 10.1038/Nm1008-1016  0.674
2008 McMahon MA, Siliciano JD, Lai J, Liu JO, Stivers JT, Siliciano RF, Kohli RM. The antiherpetic drug acyclovir inhibits HIV replication and selects the V75I reverse transcriptase multidrug resistance mutation. The Journal of Biological Chemistry. 283: 31289-93. PMID 18818198 DOI: 10.1074/Jbc.C800188200  0.82
2008 Han Y, Lin YB, An W, Xu J, Yang HC, O'Connell K, Dordai D, Boeke JD, Siliciano JD, Siliciano RF. Orientation-dependent regulation of integrated HIV-1 expression by host gene transcriptional readthrough. Cell Host & Microbe. 4: 134-46. PMID 18692773 DOI: 10.1016/J.Chom.2008.06.008  0.836
2008 Shen L, Siliciano RF. Viral reservoirs, residual viremia, and the potential of highly active antiretroviral therapy to eradicate HIV infection. The Journal of Allergy and Clinical Immunology. 122: 22-8. PMID 18602567 DOI: 10.1016/J.Jaci.2008.05.033  0.681
2008 Zhou Y, Shen L, Yang HC, Siliciano RF. Preferential cytolysis of peripheral memory CD4+ T cells by in vitro X4-tropic human immunodeficiency virus type 1 infection before the completion of reverse transcription. Journal of Virology. 82: 9154-63. PMID 18596085 DOI: 10.1128/Jvi.00773-08  0.785
2008 Chase AJ, Yang HC, Zhang H, Blankson JN, Siliciano RF. Preservation of FoxP3+ regulatory T cells in the peripheral blood of human immunodeficiency virus type 1-infected elite suppressors correlates with low CD4+ T-cell activation. Journal of Virology. 82: 8307-15. PMID 18579608 DOI: 10.1128/Jvi.00520-08  0.822
2008 Shen L, Peterson S, Sedaghat AR, McMahon MA, Callender M, Zhang H, Zhou Y, Pitt E, Anderson KS, Acosta EP, Siliciano RF. Dose-response curve slope sets class-specific limits on inhibitory potential of anti-HIV drugs. Nature Medicine. 14: 762-6. PMID 18552857 DOI: 10.1038/Nm1777  0.839
2008 Halwani R, Boyer JD, Yassine-Diab B, Haddad EK, Robinson TM, Kumar S, Parkinson R, Wu L, Sidhu MK, Phillipson-Weiner R, Pavlakis GN, Felber BK, Lewis MG, Shen A, Siliciano RF, et al. Therapeutic vaccination with simian immunodeficiency virus (SIV)-DNA + IL-12 or IL-15 induces distinct CD8 memory subsets in SIV-infected macaques. Journal of Immunology (Baltimore, Md. : 1950). 180: 7969-79. PMID 18523260 DOI: 10.4049/Jimmunol.180.12.7969  0.598
2008 Bailey JR, O'Connell K, Yang HC, Han Y, Xu J, Jilek B, Williams TM, Ray SC, Siliciano RF, Blankson JN. Transmission of human immunodeficiency virus type 1 from a patient who developed AIDS to an elite suppressor. Journal of Virology. 82: 7395-410. PMID 18495769 DOI: 10.1128/Jvi.00800-08  0.879
2008 Dinoso JB, Kim SY, Siliciano RF, Blankson JN. A comparison of viral loads between HIV-1-infected elite suppressors and individuals who receive suppressive highly active antiretroviral therapy. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 47: 102-4. PMID 18494606 DOI: 10.1086/588791  0.85
2008 Dobrowsky TM, Zhou Y, Sun SX, Siliciano RF, Wirtz D. Monitoring early fusion dynamics of human immunodeficiency virus type 1 at single-molecule resolution. Journal of Virology. 82: 7022-33. PMID 18480458 DOI: 10.1128/Jvi.00053-08  0.473
2008 Sasadeusz J, Audsley J, Mijch A, Baden R, Caro J, Hunter H, Matthews G, McMahon MA, Olender SA, Siliciano RF, Lewin SR, Thio CL. The anti-HIV activity of entecavir: a multicentre evaluation of lamivudine-experienced and lamivudine-naive patients. Aids (London, England). 22: 947-55. PMID 18453854 DOI: 10.1097/Qad.0B013E3282Ffde91  0.794
2008 Sedaghat AR, Dinoso JB, Shen L, Wilke CO, Siliciano RF. Decay dynamics of HIV-1 depend on the inhibited stages of the viral life cycle. Proceedings of the National Academy of Sciences of the United States of America. 105: 4832-7. PMID 18362342 DOI: 10.1073/Pnas.0711372105  0.845
2008 Han Y, Lai J, Barditch-Crovo P, Gallant JE, Williams TM, Siliciano RF, Blankson JN. The role of protective HCP5 and HLA-C associated polymorphisms in the control of HIV-1 replication in a subset of elite suppressors. Aids (London, England). 22: 541-4. PMID 18301071 DOI: 10.1097/Qad.0B013E3282F470E4  0.702
2008 Sedaghat AR, Siliciano RF, Wilke CO. Low-level HIV-1 replication and the dynamics of the resting CD4+ T cell reservoir for HIV-1 in the setting of HAART. Bmc Infectious Diseases. 8: 2. PMID 18171475 DOI: 10.1186/1471-2334-8-2  0.793
2008 Sedaghat AR, German J, Teslovich TM, Cofrancesco J, Jie CC, Talbot CC, Siliciano RF. Chronic CD4+ T-cell activation and depletion in human immunodeficiency virus type 1 infection: type I interferon-mediated disruption of T-cell dynamics. Journal of Virology. 82: 1870-83. PMID 18077723 DOI: 10.1128/Jvi.02228-07  0.778
2008 Gandhi SK, Siliciano JD, Bailey JR, Siliciano RF, Blankson JN. Role of APOBEC3G/F-mediated hypermutation in the control of human immunodeficiency virus type 1 in elite suppressors. Journal of Virology. 82: 3125-30. PMID 18077705 DOI: 10.1128/Jvi.01533-07  0.715
2008 Domaoal RA, McMahon M, Thio CL, Bailey CM, Tirado-Rives J, Obikhod A, Detorio M, Rapp KL, Siliciano RF, Schinazi RF, Anderson KS. Pre-steady-state kinetic studies establish entecavir 5'-triphosphate as a substrate for HIV-1 reverse transcriptase. The Journal of Biological Chemistry. 283: 5452-9. PMID 17962184 DOI: 10.1074/Jbc.M707834200  0.809
2007 Han Y, Siliciano RF. Keeping quiet: microRNAs in HIV-1 latency. Nature Medicine. 13: 1138-40. PMID 17917655 DOI: 10.1038/Nm1007-1138  0.763
2007 Chase AJ, Sedaghat AR, German JR, Gama L, Zink MC, Clements JE, Siliciano RF. Severe depletion of CD4+ CD25+ regulatory T cells from the intestinal lamina propria but not peripheral blood or lymph nodes during acute simian immunodeficiency virus infection. Journal of Virology. 81: 12748-57. PMID 17855517 DOI: 10.1128/Jvi.00841-07  0.756
2007 Sedaghat AR, Siliciano JD, Brennan TP, Wilke CO, Siliciano RF. Limits on replenishment of the resting CD4+ T cell reservoir for HIV in patients on HAART. Plos Pathogens. 3: e122. PMID 17784786 DOI: 10.1371/Journal.Ppat.0030122  0.789
2007 Peterson S, Reid AP, Kim S, Siliciano RF. Treatment implications of the latent reservoir for HIV-1. Advances in Pharmacology (San Diego, Calif.). 55: 411-25. PMID 17586322 DOI: 10.1016/S1054-3589(07)55012-X  0.581
2007 McMahon MA, Jilek BL, Brennan TP, Shen L, Zhou Y, Wind-Rotolo M, Xing S, Bhat S, Hale B, Hegarty R, Chong CR, Liu JO, Siliciano RF, Thio CL. The HBV drug entecavir - effects on HIV-1 replication and resistance. The New England Journal of Medicine. 356: 2614-21. PMID 17582071 DOI: 10.1056/Nejmoa067710  0.875
2007 Bailey JR, Zhang H, Wegweiser BW, Yang HC, Herrera L, Ahonkhai A, Williams TM, Siliciano RF, Blankson JN. Evolution of HIV-1 in an HLA-B*57-positive patient during virologic escape. The Journal of Infectious Diseases. 196: 50-5. PMID 17538883 DOI: 10.1086/518515  0.837
2007 Siliciano JD, Lai J, Callender M, Pitt E, Zhang H, Margolick JB, Gallant JE, Cofrancesco J, Moore RD, Gange SJ, Siliciano RF. Stability of the latent reservoir for HIV-1 in patients receiving valproic acid. The Journal of Infectious Diseases. 195: 833-6. PMID 17299713 DOI: 10.1086/511823  0.619
2007 Han Y, Wind-Rotolo M, Yang HC, Siliciano JD, Siliciano RF. Experimental approaches to the study of HIV-1 latency. Nature Reviews. Microbiology. 5: 95-106. PMID 17224919 DOI: 10.1038/Nrmicro1580  0.841
2007 Shen A, Yang HC, Zhou Y, Chase AJ, Boyer JD, Zhang H, Margolick JB, Zink MC, Clements JE, Siliciano RF. Novel pathway for induction of latent virus from resting CD4(+) T cells in the simian immunodeficiency virus/macaque model of human immunodeficiency virus type 1 latency. Journal of Virology. 81: 1660-70. PMID 17151130 DOI: 10.1128/Jvi.01396-06  0.831
2007 Blankson JN, Bailey JR, Thayil S, Yang HC, Lassen K, Lai J, Gandhi SK, Siliciano JD, Williams TM, Siliciano RF. Isolation and characterization of replication-competent human immunodeficiency virus type 1 from a subset of elite suppressors. Journal of Virology. 81: 2508-18. PMID 17151109 DOI: 10.1128/Jvi.02165-06  0.875
2007 Fung HK, Floudas CA, Taylor MS, Siliciano RF. A new de novo approach for optimizing peptides that inhibit HIV-1 entry Computer-Aided Chemical Engineering. 24: 959-964. DOI: 10.1016/S1570-7946(07)80184-2  0.484
2006 Siliciano JD, Siliciano RF. The latent reservoir for HIV-1 in resting CD4+ T cells: a barrier to cure. Current Opinion in Hiv and Aids. 1: 121-8. PMID 19372795 DOI: 10.1097/01.Coh.0000209582.82328.B8  0.681
2006 Haggerty CM, Pitt E, Siliciano RF. The latent reservoir for HIV-1 in resting CD4+ T cells and other viral reservoirs during chronic infection: insights from treatment and treatment-interruption trials. Current Opinion in Hiv and Aids. 1: 62-8. PMID 19372786 DOI: 10.1097/01.Coh.0000191897.78309.70  0.677
2006 Lassen KG, Ramyar KX, Bailey JR, Zhou Y, Siliciano RF. Nuclear retention of multiply spliced HIV-1 RNA in resting CD4+ T cells. Plos Pathogens. 2: e68. PMID 16839202 DOI: 10.1371/Journal.Ppat.0020068  0.865
2006 Bailey JR, Sedaghat AR, Kieffer T, Brennan T, Lee PK, Wind-Rotolo M, Haggerty CM, Kamireddi AR, Liu Y, Lee J, Persaud D, Gallant JE, Cofrancesco J, Quinn TC, Wilke CO, ... ... Siliciano RF, et al. Residual human immunodeficiency virus type 1 viremia in some patients on antiretroviral therapy is dominated by a small number of invariant clones rarely found in circulating CD4+ T cells. Journal of Virology. 80: 6441-57. PMID 16775332 DOI: 10.1128/Jvi.00591-06  0.858
2006 Bailey JR, Williams TM, Siliciano RF, Blankson JN. Maintenance of viral suppression in HIV-1-infected HLA-B*57+ elite suppressors despite CTL escape mutations. The Journal of Experimental Medicine. 203: 1357-69. PMID 16682496 DOI: 10.1084/Jem.20052319  0.664
2006 Bailey JR, Lassen KG, Yang HC, Quinn TC, Ray SC, Blankson JN, Siliciano RF. Neutralizing antibodies do not mediate suppression of human immunodeficiency virus type 1 in elite suppressors or selection of plasma virus variants in patients on highly active antiretroviral therapy. Journal of Virology. 80: 4758-70. PMID 16641269 DOI: 10.1128/Jvi.80.10.4758-4770.2006  0.874
2006 Nettles RE, Kieffer TL, Parsons T, Johnson J, Cofrancesco J, Gallant JE, Carson KA, Siliciano RF, Flexner C. Marked intraindividual variability in antiretroviral concentrations may limit the utility of therapeutic drug monitoring. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 42: 1189-96. PMID 16575741 DOI: 10.1086/501458  0.701
2006 Lee PK, Kieffer TL, Siliciano RF, Nettles RE. HIV-1 viral load blips are of limited clinical significance. The Journal of Antimicrobial Chemotherapy. 57: 803-5. PMID 16533823 DOI: 10.1093/Jac/Dkl092  0.767
2006 Blankson JN, Bailey JR, Siliciano RF. Crosscurrents in HIV-1 evolution. Nature Immunology. 7: 121-2. PMID 16424885 DOI: 10.1038/Ni0206-121  0.721
2006 Chase A, Zhou Y, Siliciano RF. HIV-1-induced depletion of CD4+ T cells in the gut: mechanism and therapeutic implications. Trends in Pharmacological Sciences. 27: 4-7. PMID 16337692 DOI: 10.1016/J.Tips.2005.11.005  0.571
2006 Chase AJ, Sedaghat AR, German JR, Gama L, Zink MC, Clements JE, Siliciano RF. Perturbations in the CD4+CD25+ regulatory T cell population of the GALT during acute SIV infection Retrovirology. 3. DOI: 10.1186/1742-4690-3-S1-S88  0.732
2006 Siliciano RF. HIV replication and evolution in patients on highly active antiretroviral therapy Retrovirology. 3. DOI: 10.1186/1742-4690-3-S1-S11  0.672
2006 Nettles RE, Kieffer TL, Parsons T, Johnson J, Cofrancesco J, Gallant JE, Carson KA, Siliciano RF, Flexner CW. Erratum: Marked intraindividual variability in antiretrovrial concentrations may limit the utility of therapeutic drug monitoring (Clinical Infectious Diseases (April 15, 2006) 42 (1189-1196)) Clinical Infectious Diseases. 43. DOI: 10.1086/507697  0.627
2005 Nettles RE, Keiffer TL, Cofrancesco J, Gallant JE, Quinn T, Jackson B, Flexner C, Carson KA, Wu AW, Siliciano RF. Psychological distress and physical pain appear to have no short-term adverse impact on plasma HIV-1 RNA levels in patients on successful HAART. Hiv Clinical Trials. 6: 262-71. PMID 16425464 DOI: 10.1310/5X2L-Mvy7-Yqtb-Ebaj  0.538
2005 Siliciano JM, Siliciano RF. Targeting HIV reservoirs with valproic acid. The Hopkins Hiv Report : a Bimonthly Newsletter For Healthcare Providers / Johns Hopkins University Aids Service. 17: 8-9. PMID 16419304  0.427
2005 Siliciano RF. Scientific rationale for antiretroviral therapy in 2005: viral reservoirs and resistance evolution. Topics in Hiv Medicine : a Publication of the International Aids Society, Usa. 13: 96-100. PMID 16170226  0.57
2005 Siliciano JD, Siliciano RF. Enhanced culture assay for detection and quantitation of latently infected, resting CD4+ T-cells carrying replication-competent virus in HIV-1-infected individuals. Methods in Molecular Biology (Clifton, N.J.). 304: 3-15. PMID 16061962 DOI: 10.1385/1-59259-907-9:003  0.702
2005 Carruth LM, Zink MC, Tarwater PM, Miller MD, Li M, Queen LA, Mankowski JL, Shen A, Siliciano RF, Clements JE. SIV-specific T lymphocyte responses in PBMC and lymphoid tissues of SIV-infected pigtailed macaques during suppressive combination antiretroviral therapy. Journal of Medical Primatology. 34: 109-21. PMID 15860119 DOI: 10.1111/J.1600-0684.2005.00103.X  0.641
2005 Blankson JN, Siliciano JD, Siliciano RF. The Effect of early treatment on the latent reservoir of HIV-1. The Journal of Infectious Diseases. 191: 1394-6. PMID 15809894 DOI: 10.1086/428783  0.582
2005 Monie D, Simmons RP, Nettles RE, Kieffer TL, Zhou Y, Zhang H, Karmon S, Ingersoll R, Chadwick K, Zhang H, Margolick JB, Quinn TC, Ray SC, Wind-Rotolo M, Miller M, ... ... Siliciano RF, et al. A novel assay allows genotyping of the latent reservoir for human immunodeficiency virus type 1 in the resting CD4+ T cells of viremic patients. Journal of Virology. 79: 5185-202. PMID 15795302 DOI: 10.1128/Jvi.79.8.5185-5202.2005  0.887
2005 Nettles RE, Kieffer TL, Kwon P, Monie D, Han Y, Parsons T, Cofrancesco J, Gallant JE, Quinn TC, Jackson B, Flexner C, Carson K, Ray S, Persaud D, Siliciano RF. Intermittent HIV-1 viremia (Blips) and drug resistance in patients receiving HAART. Jama. 293: 817-29. PMID 15713771 DOI: 10.1001/Jama.293.7.817  0.863
2005 Boyer JD, Robinson TM, Maciag PC, Peng X, Johnson RS, Pavlakis G, Lewis MG, Shen A, Siliciano R, Brown CR, Weiner DB, Paterson Y. DNA prime Listeria boost induces a cellular immune response to SIV antigens in the rhesus macaque model that is capable of limited suppression of SIV239 viral replication. Virology. 333: 88-101. PMID 15708595 DOI: 10.1016/J.Virol.2004.12.026  0.57
2005 Zhou Y, Zhang H, Siliciano JD, Siliciano RF. Kinetics of human immunodeficiency virus type 1 decay following entry into resting CD4+ T cells. Journal of Virology. 79: 2199-210. PMID 15681422 DOI: 10.1128/Jvi.79.4.2199-2210.2005  0.71
2005 Kieffer TL, Kwon P, Nettles RE, Han Y, Ray SC, Siliciano RF. G-->A hypermutation in protease and reverse transcriptase regions of human immunodeficiency virus type 1 residing in resting CD4+ T cells in vivo. Journal of Virology. 79: 1975-80. PMID 15650227 DOI: 10.1128/Jvi.79.3.1975-1980.2005  0.811
2005 Wong SB, Siliciano RF. Contribution of virus-like particles to the immunogenicity of human immunodeficiency virus type 1 Gag-derived vaccines in mice. Journal of Virology. 79: 1701-12. PMID 15650195 DOI: 10.1128/Jvi.79.3.1701-1712.2005  0.829
2005 Lassen KG, Ramyar KX, Bailey JR, Zhou Y, Siliciano RF. Retrovirology. 2: S74. DOI: 10.1186/1742-4690-2-S1-S74  0.865
2004 Lassen K, Han Y, Zhou Y, Siliciano J, Siliciano RF. The multifactorial nature of HIV-1 latency. Trends in Molecular Medicine. 10: 525-31. PMID 15519278 DOI: 10.1016/J.Molmed.2004.09.006  0.869
2004 Nettles RE, Kieffer TL, Simmons RP, Cofrancesco J, Moore RD, Gallant JE, Persaud D, Siliciano RF. Genotypic resistance in HIV-1-infected patients with persistently detectable low-level viremia while receiving highly active antiretroviral therapy. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 39: 1030-7. PMID 15472857 DOI: 10.1086/423388  0.777
2004 Kieffer T, Siliciano R. Averting the evolution of drug resistance. The Hopkins Hiv Report : a Bimonthly Newsletter For Healthcare Providers. 16: 9-10. PMID 15386837  0.6
2004 Simmons R, Siliciano RF. Can antiretroviral therapy ever be stopped? An update. The Aids Reader. 14: 435-8, 441-2. PMID 15338523  0.464
2004 Wong SB, Buck CB, Shen X, Siliciano RF. An evaluation of enforced rapid proteasomal degradation as a means of enhancing vaccine-induced CTL responses. Journal of Immunology (Baltimore, Md. : 1950). 173: 3073-83. PMID 15322167 DOI: 10.4049/Jimmunol.173.5.3073  0.83
2004 Lassen KG, Bailey JR, Siliciano RF. Analysis of human immunodeficiency virus type 1 transcriptional elongation in resting CD4+ T cells in vivo. Journal of Virology. 78: 9105-14. PMID 15308706 DOI: 10.1128/Jvi.78.17.9105-9114.2004  0.871
2004 Bailey J, Blankson JN, Wind-Rotolo M, Siliciano RF. Mechanisms of HIV-1 escape from immune responses and antiretroviral drugs. Current Opinion in Immunology. 16: 470-6. PMID 15245741 DOI: 10.1016/J.Coi.2004.05.005  0.761
2004 Han Y, Lassen K, Monie D, Sedaghat AR, Shimoji S, Liu X, Pierson TC, Margolick JB, Siliciano RF, Siliciano JD. Resting CD4+ T cells from human immunodeficiency virus type 1 (HIV-1)-infected individuals carry integrated HIV-1 genomes within actively transcribed host genes. Journal of Virology. 78: 6122-33. PMID 15163705 DOI: 10.1128/Jvi.78.12.6122-6133.2004  0.884
2004 Siliciano JD, Siliciano RF. A long-term latent reservoir for HIV-1: discovery and clinical implications. The Journal of Antimicrobial Chemotherapy. 54: 6-9. PMID 15163657 DOI: 10.1093/Jac/Dkh292  0.639
2004 Wang Z, La Rosa C, Mekhoubad S, Lacey SF, Villacres MC, Markel S, Longmate J, Ellenhorn JD, Siliciano RF, Buck C, Britt WJ, Diamond DJ. Attenuated poxviruses generate clinically relevant frequencies of CMV-specific T cells. Blood. 104: 847-56. PMID 15090456 DOI: 10.1182/Blood-2003-10-3469  0.369
2004 Kieffer TL, Finucane MM, Nettles RE, Quinn TC, Broman KW, Ray SC, Persaud D, Siliciano RF. Genotypic analysis of HIV-1 drug resistance at the limit of detection: virus production without evolution in treated adults with undetectable HIV loads. The Journal of Infectious Diseases. 189: 1452-65. PMID 15073683 DOI: 10.1086/382488  0.783
2004 Zhang H, Zhou Y, Alcock C, Kiefer T, Monie D, Siliciano J, Li Q, Pham P, Cofrancesco J, Persaud D, Siliciano RF. Novel single-cell-level phenotypic assay for residual drug susceptibility and reduced replication capacity of drug-resistant human immunodeficiency virus type 1. Journal of Virology. 78: 1718-29. PMID 14747537 DOI: 10.1128/Jvi.78.4.1718-1729.2004  0.813
2004 Persaud D, Siberry GK, Ahonkhai A, Kajdas J, Monie D, Hutton N, Watson DC, Quinn TC, Ray SC, Siliciano RF. Continued production of drug-sensitive human immunodeficiency virus type 1 in children on combination antiretroviral therapy who have undetectable viral loads. Journal of Virology. 78: 968-79. PMID 14694128 DOI: 10.1128/Jvi.78.2.968-979.2004  0.84
2004 Sedaghat AR, Siliciano RF. Immunodeficiency in HIV-1 Infection Aids and Other Manifestations of Hiv Infection. 265-283. DOI: 10.1016/B978-012764051-8/50013-5  0.716
2003 Mansharamani M, Graham DR, Monie D, Lee KK, Hildreth JE, Siliciano RF, Wilson KL. Barrier-to-autointegration factor BAF binds p55 Gag and matrix and is a host component of human immunodeficiency virus type 1 virions. Journal of Virology. 77: 13084-92. PMID 14645565 DOI: 10.1128/Jvi.77.24.13084-13092.2003  0.847
2003 Daftarian P, Ali S, Sharan R, Lacey SF, La Rosa C, Longmate J, Buck C, Siliciano RF, Diamond DJ. Immunization with Th-CTL fusion peptide and cytosine-phosphate-guanine DNA in transgenic HLA-A2 mice induces recognition of HIV-infected T cells and clears vaccinia virus challenge. Journal of Immunology (Baltimore, Md. : 1950). 171: 4028-39. PMID 14530323 DOI: 10.4049/Jimmunol.171.8.4028  0.455
2003 Hermankova M, Siliciano JD, Zhou Y, Monie D, Chadwick K, Margolick JB, Quinn TC, Siliciano RF. Analysis of human immunodeficiency virus type 1 gene expression in latently infected resting CD4+ T lymphocytes in vivo. Journal of Virology. 77: 7383-92. PMID 12805437 DOI: 10.1128/Jvi.77.13.7383-7392.2003  0.891
2003 Siliciano JD, Kajdas J, Finzi D, Quinn TC, Chadwick K, Margolick JB, Kovacs C, Gange SJ, Siliciano RF. Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells. Nature Medicine. 9: 727-8. PMID 12754504 DOI: 10.1038/Nm880  0.841
2003 Shen A, Zink MC, Mankowski JL, Chadwick K, Margolick JB, Carruth LM, Li M, Clements JE, Siliciano RF. Resting CD4+ T lymphocytes but not thymocytes provide a latent viral reservoir in a simian immunodeficiency virus-Macaca nemestrina model of human immunodeficiency virus type 1-infected patients on highly active antiretroviral therapy. Journal of Virology. 77: 4938-49. PMID 12663799 DOI: 10.1128/Jvi.77.8.4938-4949.2003  0.716
2003 Persaud D, Zhou Y, Siliciano JM, Siliciano RF. Latency in human immunodeficiency virus type 1 infection: no easy answers. Journal of Virology. 77: 1659-65. PMID 12525599 DOI: 10.1128/Jvi.77.3.1659-1665.2003  0.615
2002 Shen X, Wong SB, Buck CB, Zhang J, Siliciano RF. Direct priming and cross-priming contribute differentially to the induction of CD8+ CTL following exposure to vaccinia virus via different routes. Journal of Immunology (Baltimore, Md. : 1950). 169: 4222-9. PMID 12370352 DOI: 10.4049/Jimmunol.169.8.4222  0.815
2002 Ruff CT, Ray SC, Kwon P, Zinn R, Pendleton A, Hutton N, Ashworth R, Gange S, Quinn TC, Siliciano RF, Persaud D. Persistence of wild-type virus and lack of temporal structure in the latent reservoir for human immunodeficiency virus type 1 in pediatric patients with extensive antiretroviral exposure. Journal of Virology. 76: 9481-92. PMID 12186930 DOI: 10.1128/Jvi.76.18.9481-9492.2002  0.671
2002 Pierson TC, Zhou Y, Kieffer TL, Ruff CT, Buck C, Siliciano RF. Molecular characterization of preintegration latency in human immunodeficiency virus type 1 infection. Journal of Virology. 76: 8518-31. PMID 12163571 DOI: 10.1128/Jvi.76.17.8518-8513.2002  0.867
2002 Blankson JN, Gallant JE, Quinn TC, Bartlett JG, Siliciano RF. Loss of HIV-1-specific immunity during treatment interruption in 2 chronically infected patients. Jama. 288: 162-4. PMID 12095377 DOI: 10.1001/Jama.288.2.162-A  0.542
2002 Pierson TC, Kieffer TL, Ruff CT, Buck C, Gange SJ, Siliciano RF. Intrinsic stability of episomal circles formed during human immunodeficiency virus type 1 replication. Journal of Virology. 76: 4138-44. PMID 11907256 DOI: 10.1128/Jvi.76.8.4138-4144.2002  0.869
2002 Blankson JN, Persaud D, Siliciano RF. The challenge of viral reservoirs in HIV-1 infection. Annual Review of Medicine. 53: 557-93. PMID 11818490 DOI: 10.1146/Annurev.Med.53.082901.104024  0.687
2002 Saavedra-Lozano J, McCoig C, Xu J, Cao Y, Keiser P, Ghetie V, Siliciano RF, Siliciano JD, Picker LJ, Ramilo O, Vitetta ES. An anti-CD45RO immunotoxin kills latently infected human immunodeficiency virus (HIV) CD4 T cells in the blood of HIV-positive persons. The Journal of Infectious Diseases. 185: 306-14. PMID 11807712 DOI: 10.1086/338565  0.698
2001 Hermankova M, Ray SC, Ruff C, Powell-Davis M, Ingersoll R, D'Aquila RT, Quinn TC, Siliciano JD, Siliciano RF, Persaud D. HIV-1 drug resistance profiles in children and adults with viral load of <50 copies/ml receiving combination therapy. Jama. 286: 196-207. PMID 11448283 DOI: 10.1001/Jama.286.2.196  0.873
2001 Blankson JN, Siliciano RF. Mhc class II genotype and the control of viremia in HIV-1-infected individuals on highly active antiretroviral therapy Journal of Clinical Investigation. 107: 549-551. PMID 11238554 DOI: 10.1172/Jci12430  0.667
2001 Blankson JN, Gallant JE, Siliciano RF. Proliferative responses to human immunodeficiency virus type 1 (HIV-1) antigens in HIV-1-infected patients with immune reconstitution Journal of Infectious Diseases. 183: 657-661. PMID 11170994 DOI: 10.1086/318545  0.7
2001 Buck CB, Shen X, Egan MA, Pierson TC, Walker CM, Siliciano RF. The human immunodeficiency virus type 1 gag gene encodes an internal ribosome entry site. Journal of Virology. 75: 181-91. PMID 11119587 DOI: 10.1128/Jvi.75.1.181-191.2001  0.805
2000 Shen X, Siliciano RF. Preventing AIDS but not HIV-1 infection with a DNA vaccine. Science (New York, N.Y.). 290: 463-5. PMID 11183769 DOI: 10.1126/Science.290.5491.463  0.754
2000 Shen A, Siliciano JD, Pierson TC, Buck CB, Siliciano RF. Establishment of latent HIV-1 infection of resting CD4(+) T lymphocytes does not require inactivation of Vpr. Virology. 278: 227-33. PMID 11112497 DOI: 10.1006/Viro.2000.0650  0.858
2000 Gupta K, Ott D, Hope TJ, Siliciano RF, Boeke JD. A human nuclear shuttling protein that interacts with human immunodeficiency virus type 1 matrix is packaged into virions. Journal of Virology. 74: 11811-24. PMID 11090181 DOI: 10.1128/Jvi.74.24.11811-11824.2000  0.569
2000 Blankson JN, Finzi D, Pierson TC, Sabundayo BP, Chadwick K, Margolick JB, Quinn TC, Siliciano RF. Biphasic decay of latently infected CD4+ T cells in acute human immunodeficiency virus type 1 infection. The Journal of Infectious Diseases. 182: 1636-42. PMID 11069234 DOI: 10.1086/317615  0.881
2000 Siliciano JD, Siliciano RF. Latency and viral persistence in HIV-1 infection Journal of Clinical Investigation. 106: 823-825. PMID 11018068 DOI: 10.1172/Jci11246  0.701
2000 Martinez-Picado J, DePasquale MP, Kartsonis N, Hanna GJ, Wong J, Finzi D, Rosenberg E, Gunthard HF, Sutton L, Savara A, Petropoulos CJ, Hellmann N, Walker BD, Richman DD, Siliciano R, et al. Antiretroviral resistance during successful therapy of HIV type 1 infection. Proceedings of the National Academy of Sciences of the United States of America. 97: 10948-53. PMID 11005867 DOI: 10.1073/Pnas.97.20.10948  0.855
2000 Pierson T, Hoffman TL, Blankson J, Finzi D, Chadwick K, Margolick JB, Buck C, Siliciano JD, Doms RW, Siliciano RF. Characterization of chemokine receptor utilization of viruses in the latent reservoir for human immunodeficiency virus type 1. Journal of Virology. 74: 7824-33. PMID 10933689 DOI: 10.1128/Jvi.74.17.7824-7833.2000  0.874
2000 Blackson J, Siliciano RF. Interleukin 2 treatment for HIV infection Journal of the American Medical Association. 284: 236-238. PMID 10889599 DOI: 10.1001/Jama.284.2.236  0.594
2000 Finzi D, Siliciano RF. Taking aim at HIV replication. Nature Medicine. 6: 735-6. PMID 10888911 DOI: 10.1038/77444  0.82
2000 Pierson T, McArthur J, Siliciano RF. Reservoirs for HIV-1: Mechanisms for viral persistence in the presence of antiviral immune responses and antiretroviral therapy Annual Review of Immunology. 18: 665-708. PMID 10837072 DOI: 10.1146/Annurev.Immunol.18.1.665  0.815
2000 Persaud D, Pierson T, Ruff C, Finzi D, Chadwick KR, Margolick JB, Ruff A, Hutton N, Ray S, Siliciano RF. A stable latent reservoir for HIV-1 in resting CD4(+) T lymphocytes in infected children. The Journal of Clinical Investigation. 105: 995-1003. PMID 10749578 DOI: 10.1172/Jci9006  0.868
1999 Siliciano RF. Latency and reservoirs for HIV-1 Aids. 13. PMID 10885762  0.504
1999 Lori F, Jessen H, Lieberman J, Finzi D, Rosenberg E, Tinelli C, Walker B, Siliciano RF, Lisziewicz J. Treatment of human immunodeficiency virus infection with hydroxyurea, didanosine, and a protease inhibitor before seroconversion is associated with normalized immune parameters and limited viral reservoir. The Journal of Infectious Diseases. 180: 1827-32. PMID 10558937 DOI: 10.1086/315113  0.86
1999 Carruth LM, Greten TF, Murray CE, Castro MG, Crone SN, Pavlat W, Schneck JP, Siliciano RF. An algorithm for evaluating human cytotoxic T lymphocyte responses to candidate AIDS vaccines. Aids Research and Human Retroviruses. 15: 1021-34. PMID 10445814 DOI: 10.1089/088922299310539  0.612
1999 Lisziewicz J, Rosenberg E, Lieberman J, Jessen H, Lopalco L, Siliciano R, Walker B, Lori F. Control of HIV despite the discontinuation of antiretroviral therapy. The New England Journal of Medicine. 340: 1683-4. PMID 10348681 DOI: 10.1056/Nejm199905273402114  0.677
1999 Finzi D, Blankson J, Siliciano JD, Margolick JB, Chadwick K, Pierson T, Smith K, Lisziewicz J, Lori F, Flexner C, Quinn TC, Chaisson RE, Rosenberg E, Walker B, Gange S, ... ... Siliciano RF, et al. Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy. Nature Medicine. 5: 512-7. PMID 10229227 DOI: 10.1038/8394  0.873
1999 Blankson J, Persaud D, Siliciano RF. Latent reservoirs for HIV-1 Current Opinion in Infectious Diseases. 12: 5-11. DOI: 10.1097/00001432-199902000-00002  0.637
1998 Siliciano RF. A reservoir for HIV in patients on combination antiretroviral therapy The Hopkins Hiv Report : a Bimonthly Newsletter For Healthcare Providers / Johns Hopkins University Aids Service. 10. PMID 11365130  0.617
1998 Lisziewicz J, Jessen H, Finzi D, Siliciano RF, Lori F. HIV-1 suppression by early treatment with hydroxyurea, didanosine, and a protease inhibitor. Lancet (London, England). 352: 199-200. PMID 9683211 DOI: 10.1016/S0140-6736(98)24029-3  0.854
1998 Johnson RP, Siliciano RF, McElrath MJ. Cellular immune responses to HIV-1 Aids (London, England). 12. PMID 9632992  0.435
1998 Finzi D, Siliciano RF. Viral dynamics in HIV-1 infection. Cell. 93: 665-71. PMID 9630210 DOI: 10.1016/S0092-8674(00)81427-0  0.835
1998 Clements-Mann ML, Weinhold K, Matthews TJ, Graham BS, Gorse GJ, Keefer MC, McElrath MJ, Hsieh RH, Mestecky J, Zolla-Pazner S, Mascola J, Schwartz D, Siliciano R, Corey L, Wright PF, et al. Immune responses to human immunodeficiency virus (HIV) type 1 induced by canarypox expressing HIV-1MN gp120, HIV-1SF2 recombinant gp120, or both vaccines in seronegative adults. NIAID AIDS Vaccine Evaluation Group. The Journal of Infectious Diseases. 177: 1230-46. PMID 9593008 DOI: 10.1086/515288  0.59
1998 Ray SC, Lubaki N, Dhruva BR, Siliciano RF, Bollinger RC. Autologous strain-specific cytolytic T lymphocyte responses directed against human immunodeficiency virus type 1 Env Aids Research and Human Retroviruses. 14: 3-13. PMID 9453246 DOI: 10.1089/Aid.1998.14.3  0.645
1998 Persaud D, Finzi D, Chadwick K, Margolick J, Hutton N, Siliciano R. Quantitative Analysis of Latently Infected Resting CD4+ T Lymphocytes in Children with Perinatally Acquired Human Immunodeficiency Virus Type-1 Infection ♦ 888 Pediatric Research. 43: 153-153. DOI: 10.1203/00006450-199804001-00909  0.8
1997 Egan MA, Carruth LM, Rowell JF, Yu X, Siliciano RF. The ins and outs of HIV endocytosis. Trends in Cell Biology. 7: 49. PMID 17708904 DOI: 10.1016/S0962-8924(97)82670-0  0.511
1997 Finzi D, Hermankova M, Pierson T, Carruth LM, Buck C, Chaisson RE, Quinn TC, Chadwick K, Margolick J, Brookmeyer R, Gallant J, Markowitz M, Ho DD, Richman DD, Siliciano RF. Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy. Science (New York, N.Y.). 278: 1295-300. PMID 9360927 DOI: 10.1126/Science.278.5341.1295  0.884
1997 Ehret R, Heinkelein M, Siliciano RF, Jassoy C. Human immunodeficiency virus glycoprotein-specific CD4+ cytotoxic T lymphocytes are involved in two types of cytotoxicity: Antigen-specific and cell-cell fusion-related cell lysis Aids Research and Human Retroviruses. 13: 1017-1021. PMID 9264288 DOI: 10.1089/Aid.1997.13.1017  0.54
1997 Lubaki NM, Ray SC, Dhruva B, Quinn TC, Siliciano RF, Bollinger RC. Characterization of a polyclonal cytolytic T lymphocyte response to human immunodeficiency virus in persons without clinical progression Journal of Infectious Diseases. 175: 1360-1367. PMID 9180175 DOI: 10.1086/516468  0.63
1997 Chun TW, Chadwick K, Margolick J, Siliciano RF. Differential susceptibility of naive and memory CD4+ T cells to the cytopathic effects of infection with human immunodeficiency virus type 1 strain LAI Journal of Virology. 71: 4436-4444. PMID 9151834 DOI: 10.1128/Jvi.71.6.4436-4444.1997  0.583
1997 Chun TW, Carruth L, Finzi D, Shen X, DiGiuseppe JA, Taylor H, Hermankova M, Chadwick K, Margolick J, Quinn TC, Kuo YH, Brookmeyer R, Zeiger MA, Barditch-Crovo P, Siliciano RF. Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection. Nature. 387: 183-8. PMID 9144289 DOI: 10.1038/387183A0  0.884
1997 Tobery TW, Siliciano RF. Targeting of HIV-1 antigens for rapid intracellular degradation enhances cytotoxic T lymphocyte (CTL) recognition and the induction of de novo CTL responses in vivo after immunization Journal of Experimental Medicine. 185: 909-920. PMID 9120397 DOI: 10.1084/Jem.185.5.909  0.515
1997 McElrath MJ, Siliciano RF, Weinhold KJ. HIV type 1 vaccine-induced cytotoxic T cell responses in phase I clinical trials: Detection, characterization, and quantitation Aids Research and Human Retroviruses. 13: 211-216. PMID 9115806  0.382
1997 Ruff AL, Guarnieri FG, Staveley-O'Carroll K, Siliciano RF, August JT. The enhanced immune response to the HIV gp160/LAMP chimeric gene product targeted to the lysosome membrane protein trafficking pathway. The Journal of Biological Chemistry. 272: 8671-8. PMID 9079699 DOI: 10.1074/Jbc.272.13.8671  0.37
1997 Liu AY, Torchia BS, Migeon BR, Siliciano RF. The human NTT gene: Identification of a novel 17-kb noncoding nuclear RNA expressed in activated CD4+ T cells Genomics. 39: 171-184. PMID 9027504 DOI: 10.1006/Geno.1996.4463  0.385
1996 Bollinger RC, Egan MA, Chun TW, Mathieson B, Siliciano RF. Cellular immune responses to HIV-1 in progressive and non-progressive infections. Aids (London, England). 10: S85-96. PMID 8883615 DOI: 10.1097/00002030-199601001-00013  0.557
1996 Egan MA, Carruth LM, Rowell JF, Yu X, Siliciano RF. Human immunodeficiency virus type 1 envelope protein endocytosis mediated by a highly conserved intrinsic internalization signal in the cytoplasmic domain of gp41 is suppressed in the presence of the Pr55gag precursor protein. Journal of Virology. 70: 6547-56. PMID 8794289 DOI: 10.1128/Jvi.70.10.6547-6556.1996  0.484
1996 Siliciano RF. The role of CD4 in HIV envelope-mediated pathogenesis Current Topics in Microbiology and Immunology. 205: 159-179. PMID 8575195 DOI: 10.1007/978-3-642-79798-9_8  0.508
1995 Egan MA, Pavlat WA, Tartaglia J, Paoletti E, Weinhold KJ, Clements ML, Siliciano RF. Induction of human immunodeficiency virus type 1 (hiv-1)-specific cytolytic t lymphocyte responses in seronegative adults by a nonreplicating, host-range-restricted canarypox vector (alvac) carrying the hiv-1mn env gene Journal of Infectious Diseases. 171: 1623-1627. PMID 7769304 DOI: 10.1093/Infdis/171.6.1623  0.656
1995 Rowell JF, Stanhope PE, Siliciano RF. Endocytosis of endogenously synthesized HIV-1 envelope protein: Mechanism and role in processing for association with class II MHC Journal of Immunology. 155: 473-488. PMID 7602119  0.329
1995 Hammond SA, Johnson RP, Kalams SA, Walker BD, Takiguchi M, Safrit JT, Koup RA, Siliciano RF. An epitope-selective, transporter associated with antigen presentation (TAP)-1/2-independent pathway and a more general TAP-1/2-dependent antigen-processing pathway allow recognition of the HIV-1 envelope glycoprotein by CD8+ CTL. Journal of Immunology (Baltimore, Md. : 1950). 154: 6140-56. PMID 7538543  0.305
1995 Chun TW, Finzi D, Margolick J, Chadwick K, Schwartz D, Siliciano RF. In vivo fate of HIV-1-infected T cells: quantitative analysis of the transition to stable latency. Nature Medicine. 1: 1284-90. PMID 7489410 DOI: 10.1038/Nm1295-1284  0.866
1994 Miskovsky EP, Liu AY, Pavlat W, Viveen R, Stanhope PE, Finzi D, Fox WM, Hruban RH, Podack ER, Siliciano RF. Studies of the mechanism of cytolysis by HIV-1-specific CD4+ human CTL clones induced by candidate AIDS vaccines. Journal of Immunology (Baltimore, Md. : 1950). 153: 2787-99. PMID 7915742  0.792
1994 Johnson RP, Hammond SA, Trocha A, Siliciano RF, Walker BD. Induction of a major histocompatibility complex class I-restricted cytotoxic T-lymphocyte response to a highly conserved region of human immunodeficiency virus type 1 (HIV-1) gp120 in seronegative humans immunized with a candidate HIV-1 vaccine. Journal of Virology. 68: 3145-53. PMID 7908700 DOI: 10.1128/Jvi.68.5.3145-3153.1994  0.564
1994 Lubaki MN, Egan MA, Siliciano RF, Weinhold KJ, Bollinger RC. A novel method for detection and ex vivo expansion of HIV type 1-specific cytolytic T lymphocytes Aids Research and Human Retroviruses. 10: 1427-1431. PMID 7888197 DOI: 10.1089/Aid.1994.10.1427  0.667
1994 Johnson RP, Hammond SA, Trocha A, Siliciano RF, Walker BD. Epitope specificity of MHC restricted cytotoxic T lymphocytes induced by candidate HIV-1 vaccine. Aids Research and Human Retroviruses. 10: S73-5. PMID 7532425  0.41
1993 Siliciano RF, Stanhope PE, Clements ML. Human CD4+ Cytolytic T Lymphocyte Responses to a Human Immunodeficiency Virus Type 1 gp160 Subunit Vaccine Journal of Infectious Diseases. 168: 92-100. PMID 8099941 DOI: 10.1093/Infdis/168.1.92  0.604
1993 Stanhope PE, Liu AY, Pavlat W, Pitha PM, Clements ML, Siliciano RF. An HIV-1 envelope protein vaccine elicits a functionally complex human CD4+ T cell response that includes cytolytic T lymphocytes Journal of Immunology. 150: 4672-4686. PMID 8097759  0.395
1993 Bollinger RC, Quinn TC, Liu AY, Stanhope PE, Hammond SA, Viveen R, Clements ML, Siliciano RF. Cytokines from vaccine-induced HIV-1 specific cytotoxic T lymphocytes: effects on viral replication. Aids Research and Human Retroviruses. 9: 1067-77. PMID 7906131 DOI: 10.1089/Aid.1993.9.1067  0.643
1993 Siliciano RF. CD4+ T cell epitopes in HIV-1 proteins Chemical Immunology. 56: 127-149. PMID 7680866 DOI: 10.1159/000319161  0.613
1992 Hammond SA, Bollinger RC, Stanhope PE, Quinn TC, Schwartz D, Clements ML, Siliciano RF. Comparative clonal analysis of human immunodeficiency virus type 1 (HIV-1)-specific CD4+ and CD8+ cytolytic T lymphocytes isolated from seronegative humans immunized with candidate HIV-1 vaccines. The Journal of Experimental Medicine. 176: 1531-42. PMID 1460417 DOI: 10.1084/Jem.176.6.1531  0.62
1992 Siliciano RF, Bollinger RC, Callahan KM, Hammond SA, Liu AY, Miskovsky EP, Rowell JF, Stanhope PE. Clonal analysis of T-cell responses to the HIV-1 envelope proteins in AIDS vaccine recipients. Aids Research and Human Retroviruses. 8: 1349-52. PMID 1361352 DOI: 10.1089/Aid.1992.8.1349  0.551
1992 Liu AY, Miskovsky EP, Stanhope PE, Siliciano RF. Production of transmembrane and secreted forms of tumor necrosis factor (TNF)-α by HIV-1-specific CD4+ cytolytic T lymphocyte clones: Evidence for a TNF-α-independent cytolytic mechanism Journal of Immunology. 148: 3789-3798. PMID 1351088  0.344
1990 Orentas RJ, Hildreth JE, Obah E, Polydefkis M, Smith GE, Clements ML, Siliciano RF. Induction of CD4+ human cytolytic T cells specific for HIV-infected cells by a gp160 subunit vaccine. Science (New York, N.Y.). 248: 1234-7. PMID 2190315 DOI: 10.1126/Science.2190315  0.647
1990 Callahan KM, Fort MM, Obah EA, Reinherz EL, Siliciano RF. Genetic variability in HIV-1 gp120 affects interactions with HLA molecules and T cell receptor. Journal of Immunology (Baltimore, Md. : 1950). 144: 3341-6. PMID 1970352  0.408
1990 Polydefkis M, Koenig S, Flexner C, Obah E, Gebo K, Chakrabarti S, Earl PL, Moss B, Siliciano RF. Anchor sequence-dependent endogenous processing of human immunodeficiency virus 1 envelope glycoprotein gp160 for CD4+ T cell recognition Journal of Experimental Medicine. 171: 875-887. PMID 1968506 DOI: 10.1084/Jem.171.3.875  0.546
1990 Koyasu S, Lawton T, Novick D, Recny MA, Siliciano RF, Wallner BP, Reinherz EL. Role of interaction of CD2 molecules with lymphocyte function-associated antigen 3 in T-cell recognition of nominal antigen Proceedings of the National Academy of Sciences of the United States of America. 87: 2603-2607. PMID 1690889 DOI: 10.1073/Pnas.87.7.2603  0.41
1989 Siliciano RF, Knall C, Lawton T, Berman P, Gregory T, Reinherz EL. Recognition of HIV glycoprotein gp120 by T cells. Role of monocyte CD4 in the presentation of gp120 Journal of Immunology. 142: 1506-1511. PMID 2537355  0.386
1988 Siliciano RF, Lawton T, Knall C, Karr RW, Berman P, Gregory T, Reinherz EL. Analysis of host-virus interactions in AIDS with anti-gp120 T cell clones: Effect of HIV sequence variation and a mechanism for CD4+ cell depletion Cell. 54: 561-575. PMID 2969774 DOI: 10.1016/0092-8674(88)90078-5  0.609
1988 Hussey RE, Richardson NE, Kowalski M, Brown NR, Chang HC, Siliciano RF, Dorfman T, Walker B, Sodroski J, Reinherz EL. A soluble CD4 protein selectively inhibits HIV replication and syncytium formation. Nature. 331: 78-81. PMID 2829023 DOI: 10.1038/331078A0  0.552
1986 Milanese C, Siliciano RF, Schmidt RE, Ritz J, Richardson NE, Reinherz EL. A lymphokine that activates the cytolytic program of both cytotoxic T lymphocyte and natural killer clones Journal of Experimental Medicine. 163: 1583-1588. PMID 3519831 DOI: 10.1084/Jem.165.1.275  0.348
1986 Siliciano RF, Hemesath TJ, Pratt JC, Dintzis RZ, Dintzis HM, Acuto O, Shin HS, Reinherz EL. Direct evidence for the existence of nominal antigen binding sites on T cell surface Ti α-β heterodimers of MHC-restricted T cell clones Cell. 47: 161-171. PMID 2945646 DOI: 10.1016/0092-8674(86)90439-3  0.307
1985 Siliciano RF, Pratt JC, Schmidt RE, Ritz J, Reinherz EL. Activation of cytolytic T lymphocyte and natural killer cell function through the T11 sheep erythrocyte binding protein Nature. 317: 428-430. PMID 2864636 DOI: 10.1038/317428A0  0.356
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