Ulla Margrete Hansen - Publications

Affiliations: 
1983-1997 Microbiology and Molecular Genetics Harvard Medical School, Boston, MA, United States 
 1998- Biology Boston University, Boston, MA, United States 
Area:
Mammalian gene regulation, Transcription, Cell cycle, Cancer
Website:
https://www.bu.edu/biology/people/profiles/ulla-hansen/

66 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Willoughby JLS, George K, Roberto MP, Chin HG, Stoiber P, Shin H, Pedamallu CS, Schaus SE, Fitzgerald K, Shah J, Hansen U. Targeting the oncogene LSF with either the small molecule inhibitor FQI1 or siRNA causes mitotic delays with unaligned chromosomes, resulting in cell death or senescence. Bmc Cancer. 20: 552. PMID 32539694 DOI: 10.1186/S12885-020-07039-1  0.31
2020 Chin HG, Esteve PO, Ruse C, Lee J, Schaus SE, Pradhan S, Hansen U. The microtubule-associated histone methyltransferase SET8, facilitated by transcription factor LSF, methylates α-tubulin. The Journal of Biological Chemistry. PMID 32111740 DOI: 10.1074/Jbc.Ra119.010951  0.333
2020 Pokharel N, Kavouris J, Biagi J, Hansen U, Schaus SE. Abstract 4021: Assessing the sensitivity of LSF inhibitors against liver cancer Cancer Research. 80: 4021-4021. DOI: 10.1158/1538-7445.Am2020-4021  0.343
2016 Acevedo-Luna N, Mariño-Ramírez L, Halbert A, Hansen U, Landsman D, Spouge JL. Most of the tight positional conservation of transcription factor binding sites near the transcription start site reflects their co-localization within regulatory modules. Bmc Bioinformatics. 17: 479. PMID 27871221 DOI: 10.1186/S12859-016-1354-5  0.375
2016 Chin HG, Ponnaluri VK, Zhang G, Estève PO, Schaus SE, Hansen U, Pradhan S. Transcription factor LSF-DNMT1 complex dissociation by FQI1 leads to aberrant DNA methylation and gene expression. Oncotarget. PMID 27845898 DOI: 10.18632/Oncotarget.13271  0.449
2015 Rajasekaran D, Siddiq A, Willoughby JL, Biagi JM, Christadore LM, Yunes SA, Gredler R, Jariwala N, Robertson CL, Akiel MA, Shen XN, Subler MA, Windle JJ, Schaus SE, Fisher PB, ... Hansen U, et al. Small molecule inhibitors of Late SV40 Factor (LSF) abrogate hepatocellular carcinoma (HCC): Evaluation using an endogenous HCC model. Oncotarget. PMID 26313006 DOI: 10.18632/Oncotarget.4656  0.352
2012 Bernelot Moens SJ, Schnitzler GR, Nickerson M, Guo H, Ueda K, Lu Q, Aronovitz MJ, Nickerson H, Baur WE, Hansen U, Iyer LK, Karas RH. Rapid estrogen receptor signaling is essential for the protective effects of estrogen against vascular injury. Circulation. 126: 1993-2004. PMID 22997253 DOI: 10.1161/Circulationaha.112.124529  0.302
2012 Santhekadur PK, Rajasekaran D, Siddiq A, Gredler R, Chen D, Schaus SE, Hansen U, Fisher PB, Sarkar D. The transcription factor LSF: a novel oncogene for hepatocellular carcinoma. American Journal of Cancer Research. 2: 269-85. PMID 22679558  0.307
2012 Grant TJ, Bishop JA, Christadore LM, Barot G, Chin HG, Woodson S, Kavouris J, Siddiq A, Gredler R, Shen XN, Sherman J, Meehan T, Fitzgerald K, Pradhan S, Briggs LA, ... ... Hansen U, et al. Antiproliferative small-molecule inhibitors of transcription factor LSF reveal oncogene addiction to LSF in hepatocellular carcinoma. Proceedings of the National Academy of Sciences of the United States of America. 109: 4503-8. PMID 22396589 DOI: 10.1073/Pnas.1121601109  0.405
2012 Schneider S, Smith T, Hansen U. SCOREM: statistical consolidation of redundant expression measures. Nucleic Acids Research. 40: e46. PMID 22210887 DOI: 10.1093/Nar/Gkr1270  0.303
2010 Saxena UH, Owens L, Graham JR, Cooper GM, Hansen U. Prolyl isomerase Pin1 regulates transcription factor LSF (TFCP2) by facilitating dephosphorylation at two serine-proline motifs. The Journal of Biological Chemistry. 285: 31139-47. PMID 20682773 DOI: 10.1074/Jbc.M109.078808  0.797
2010 Yoo BK, Emdad L, Gredler R, Fuller C, Dumur CI, Jones KH, Jackson-Cook C, Su ZZ, Chen D, Saxena UH, Hansen U, Fisher PB, Sarkar D. Transcription factor Late SV40 Factor (LSF) functions as an oncogene in hepatocellular carcinoma. Proceedings of the National Academy of Sciences of the United States of America. 107: 8357-62. PMID 20404171 DOI: 10.1073/Pnas.1000374107  0.763
2010 Traylor-Knowles N, Hansen U, Dubuc TQ, Martindale MQ, Kaufman L, Finnerty JR. The evolutionary diversification of LSF and Grainyhead transcription factors preceded the radiation of basal animal lineages. Bmc Evolutionary Biology. 10: 101. PMID 20398424 DOI: 10.1186/1471-2148-10-101  0.388
2010 Zhu N, Hansen U. Transcriptional regulation by HMGN proteins. Biochimica Et Biophysica Acta. 1799: 74-9. PMID 20123070 DOI: 10.1016/J.Bbagrm.2009.11.006  0.6
2009 Yoo BK, Gredler R, Vozhilla N, Su ZZ, Chen D, Forcier T, Shah K, Saxena U, Hansen U, Fisher PB, Sarkar D. Identification of genes conferring resistance to 5-fluorouracil. Proceedings of the National Academy of Sciences of the United States of America. 106: 12938-43. PMID 19622726 DOI: 10.1073/Pnas.0901451106  0.759
2009 Hansen U, Owens L, Saxena UH. Transcription factors LSF and E2Fs: tandem cyclists driving G0 to S? Cell Cycle (Georgetown, Tex.). 8: 2146-51. PMID 19556876 DOI: 10.4161/Cc.8.14.9089  0.794
2009 Repetny KJ, Zhong X, Holodick NE, Rothstein TL, Hansen U. Binding of LBP-1a to specific immunoglobulin switch regions in vivo correlates with specific repression of class switch recombination. European Journal of Immunology. 39: 1387-94. PMID 19384868 DOI: 10.1002/Eji.200838226  0.707
2009 Saxena UH, Powell CM, Fecko JK, Cacioppo R, Chou HS, Cooper GM, Hansen U. Phosphorylation by cyclin C/cyclin-dependent kinase 2 following mitogenic stimulation of murine fibroblasts inhibits transcriptional activity of LSF during G1 progression. Molecular and Cellular Biology. 29: 2335-45. PMID 19237534 DOI: 10.1128/Mcb.00687-08  0.636
2008 Schnoes KK, Jaffe IZ, Iyer L, Dabreo A, Aronovitz M, Newfell B, Hansen U, Rosano G, Mendelsohn ME. Rapid recruitment of temporally distinct vascular gene sets by estrogen. Molecular Endocrinology (Baltimore, Md.). 22: 2544-56. PMID 18787042 DOI: 10.1210/Me.2008-0044  0.385
2007 Zhu N, Hansen U. HMGN1 modulates estrogen-mediated transcriptional activation through interactions with specific DNA-binding transcription factors. Molecular and Cellular Biology. 27: 8859-73. PMID 17938209 DOI: 10.1128/Mcb.01724-07  0.577
2007 O'Lone R, Knorr K, Jaffe IZ, Schaffer ME, Martini PG, Karas RH, Bienkowska J, Mendelsohn ME, Hansen U. Estrogen receptors alpha and beta mediate distinct pathways of vascular gene expression, including genes involved in mitochondrial electron transport and generation of reactive oxygen species. Molecular Endocrinology (Baltimore, Md.). 21: 1281-96. PMID 17374850 DOI: 10.1210/Me.2006-0497  0.738
2005 Ylisastigui L, Kaur R, Johnson H, Volker J, He G, Hansen U, Margolis D. Mitogen-activated protein kinases regulate LSF occupancy at the human immunodeficiency virus type 1 promoter. Journal of Virology. 79: 5952-62. PMID 15857981 DOI: 10.1128/Jvi.79.10.5952-5962.2005  0.367
2005 Haverty PM, Weng Z, Hansen U. Transcriptional Regulatory Networks Activated by PI3K and ERK Transduced Growth Signals in Human Glioblastoma Cells Journal of Computer Science and Technology. 20: 439-445. DOI: 10.1007/S11390-005-0439-9  0.409
2004 Veljkovic J, Hansen U. Lineage-specific and ubiquitous biological roles of the mammalian transcription factor LSF. Gene. 343: 23-40. PMID 15563829 DOI: 10.1016/J.Gene.2004.08.010  0.76
2004 O'Lone R, Frith MC, Karlsson EK, Hansen U. Genomic targets of nuclear estrogen receptors. Molecular Endocrinology (Baltimore, Md.). 18: 1859-75. PMID 15031323 DOI: 10.1210/Me.2003-0044  0.74
2004 Frith MC, Fu Y, Yu L, Chen JF, Hansen U, Weng Z. Detection of functional DNA motifs via statistical over-representation. Nucleic Acids Research. 32: 1372-81. PMID 14988425 DOI: 10.1093/Nar/Gkh299  0.358
2004 Haverty PM, Hansen U, Weng Z. Computational inference of transcriptional regulatory networks from expression profiling and transcription factor binding site identification. Nucleic Acids Research. 32: 179-88. PMID 14704355 DOI: 10.1093/Nar/Gkh183  0.39
2003 Venkatesan K, McManus HR, Mello CC, Smith TF, Hansen U. Functional conservation between members of an ancient duplicated transcription factor family, LSF/Grainyhead. Nucleic Acids Research. 31: 4304-16. PMID 12888489 DOI: 10.1093/Nar/Gkg644  0.385
2003 Pagon Z, Volker J, Cooper GM, Hansen U. Mammalian transcription factor LSF is a target of ERK signaling. Journal of Cellular Biochemistry. 89: 733-46. PMID 12858339 DOI: 10.1002/Jcb.10549  0.416
2002 Frith MC, Spouge JL, Hansen U, Weng Z. Statistical significance of clusters of motifs represented by position specific scoring matrices in nucleotide sequences. Nucleic Acids Research. 30: 3214-24. PMID 12136103 DOI: 10.1093/Nar/Gkf438  0.316
2002 Bruni P, Minopoli G, Brancaccio T, Napolitano M, Faraonio R, Zambrano N, Hansen U, Russo T. Fe65, a ligand of the Alzheimer's beta-amyloid precursor protein, blocks cell cycle progression by down-regulating thymidylate synthase expression. The Journal of Biological Chemistry. 277: 35481-8. PMID 12089154 DOI: 10.1074/Jbc.M205227200  0.314
2002 Drouin EE, Schrader CE, Stavnezer J, Hansen U. The ubiquitously expressed DNA-binding protein late SV40 factor binds Ig switch regions and represses class switching to IgA. Journal of Immunology (Baltimore, Md. : 1950). 168: 2847-56. PMID 11884454 DOI: 10.4049/Jimmunol.168.6.2847  0.424
2001 Sewack GF, Ellis TW, Hansen U. Binding of TATA binding protein to a naturally positioned nucleosome is facilitated by histone acetylation Molecular and Cellular Biology. 21: 1404-1415. PMID 11158325 DOI: 10.1128/Mcb.21.4.1404-1415.2001  0.396
2000 Powell CM, Rudge TL, Zhu Q, Johnson LF, Hansen U. Inhibition of the mammalian transcription factor LSF induces S-phase-dependent apoptosis by downregulating thymidylate synthase expression. The Embo Journal. 19: 4665-75. PMID 10970859 DOI: 10.1093/Emboj/19.17.4665  0.423
2000 Coull JJ, Romerio F, Sun JM, Volker JL, Galvin KM, Davie JR, Shi Y, Hansen U, Margolis DM. The human factors YY1 and LSF repress the human immunodeficiency virus type 1 long terminal repeat via recruitment of histone deacetylase 1. Journal of Virology. 74: 6790-9. PMID 10888618 DOI: 10.1128/Jvi.74.15.6790-6799.2000  0.355
1999 Hansen U. Transcriptional and structural analyses of isolated SV40 chromatin Methods in Molecular Biology (Clifton, N.J.). 119: 261-290. PMID 10804518 DOI: 10.1385/1-59259-681-9:261  0.313
1998 Shirra MK, Hansen U. LSF and NTF-1 share a conserved DNA recognition motif yet require different oligomerization states to form a stable protein-DNA complex Journal of Biological Chemistry. 273: 19260-19268. PMID 9668115 DOI: 10.1074/Jbc.273.30.19260  0.358
1997 Sewack GF, Hansen U. Nucleosome positioning and transcription-associated chromatin alterations on the human estrogen-responsive pS2 promoter Journal of Biological Chemistry. 272: 31118-31129. PMID 9388265 DOI: 10.1074/Jbc.272.49.31118  0.388
1997 Ding HF, Bustin M, Hansen U. Alleviation of histone H1-mediated transcriptional repression and chromatin compaction by the acidic activation region in chromosomal protein HMG-14. Molecular and Cellular Biology. 17: 5843-55. PMID 9315642 DOI: 10.1128/Mcb.17.10.5843  0.375
1997 Hanna-Rose W, Licht JD, Hansen U. Two evolutionarily conserved repression domains in the Drosophila Kruppel protein differ in activator specificity Molecular and Cellular Biology. 17: 4820-4829. PMID 9234738 DOI: 10.1128/Mcb.17.8.4820  0.707
1997 Volker JL, Rameh LE, Zhu Q, DeCaprio J, Hansen U. Mitogenic stimulation of resting T cells causes rapid phosphorylation of the transcription factor LSF and increased DNA-binding activity. Genes & Development. 11: 1435-46. PMID 9192871 DOI: 10.1101/Gad.11.11.1435  0.439
1996 Hanna-Rose W, Hansen U. Active repression mechanisms of eukaryotic transcription repressors Trends in Genetics. 12: 229-234. PMID 8928228 DOI: 10.1016/0168-9525(96)10022-6  0.733
1996 Hansen U. Mechanisms of eukaryotic transcription: Surfaces, complexes, and contexts (Cold Spring Harbor Cancer Cells Meeting, August 30-September 3, 1995) Biochimica Et Biophysica Acta - Reviews On Cancer. 1287: 59-62. PMID 8639706 DOI: 10.1016/0304-419X(96)00004-2  0.404
1995 Casaz P, Rice PW, Cole CN, Hansen U. A TEF-1-independent mechanism for activation of the simian virus 40 (SV40) late promoter by mutant SV40 large T antigens Journal of Virology. 69: 3501-3509. PMID 7745697 DOI: 10.1128/Jvi.69.6.3501-3509.1995  0.369
1994 Licht JD, Hanna-Rose W, Reddy JC, English MA, Ro M, Grossel M, Shaknovich R, Hansen U. Mapping and mutagenesis of the amino-terminal transcriptional repression domain of the Drosophila Krüppel protein Molecular and Cellular Biology. 14: 4057-4066. PMID 8196644 DOI: 10.1128/mcb.14.6.4057-4066.1994  0.683
1994 Ding HF, Rimsky S, Batson SC, Bustin M, Hansen U. Stimulation of RNA polymerase II elongation by chromosomal protein HMG-14. Science (New York, N.Y.). 265: 796-9. PMID 8047885 DOI: 10.1126/Science.8047885  0.368
1994 Shirra MK, Zhu Q, Huang HC, Pallas D, Hansen U. One exon of the human LSF gene includes conserved regions involved in novel DNA-binding and dimerization motifs. Molecular and Cellular Biology. 14: 5076-87. PMID 8035790 DOI: 10.1128/Mcb.14.8.5076  0.403
1993 Batson SC, Rimsky S, Sundseth R, Hansen U. Association of nucleosome-free regions and basal transcription factors with in vivo-assembled chromatin templates active in vitro. Nucleic Acids Research. 21: 3459-68. PMID 8393989 DOI: 10.1093/Nar/21.15.3459  0.409
1993 Defranco C, Ro M, Grossel M, English MA, Hansen UM, Wagner JA, Licht JD. NGFIA (EGR1) Contains Transcription Activating Domains in Both the Amino Terminal and Carboxyl Terminal Regions of the Protein Biochemical and Biophysical Research Communications. 194: 425-431. PMID 8392841 DOI: 10.1006/Bbrc.1993.1837  0.407
1993 Licht JD, Ro M, English MA, Grossel M, Hansen U. Selective repression of transcriptional activators at a distance by the Drosophila Krüppel protein Proceedings of the National Academy of Sciences of the United States of America. 90: 11361-11365. PMID 8248254 DOI: 10.1073/Pnas.90.23.11361  0.45
1992 Sundseth R, Hansen U. Activation of RNA polymerase II transcription by the specific DNA-binding protein LSF: Increased rate of binding of the basal promoter factor TFIIB Journal of Biological Chemistry. 267: 7845-7855. PMID 1313810  0.319
1992 Batson SC, Sundseth R, Heath CV, Samuels M, Hansen U. In vitro initiation of transcription by RNA polymerase II on in vivo-assembled chromatin templates. Molecular and Cellular Biology. 12: 1639-51. PMID 1312666 DOI: 10.1128/Mcb.12.4.1639  0.407
1991 Casaz P, Sundseth R, Hansen U. trans activation of the simian virus 40 late promoter by large T antigen requires binding sites for the cellular transcription factor TEF-1 Journal of Virology. 65: 6535-6543. PMID 1658359 DOI: 10.1128/Jvi.65.12.6535-6543.1991  0.394
1990 Huang HC, Sundseth R, Hansen U. Transcription factor LSF binds two variant bipartite sites within the SV40 late promoter Genes and Development. 4: 287-298. PMID 2159933 DOI: 10.1101/Gad.4.2.287  0.352
1990 Licht JD, Grossel MJ, Figge J, Hansen UM. Drosophila Krüppel protein is a transcriptional represser Nature. 346: 76-79. PMID 2114551 DOI: 10.1038/346076A0  0.441
1987 Patarca R, Heath C, Goldenberg GJ, Rosen CA, Sodroski JG, Haseltine WA, Hansen UM. Transcription directed by the HIV long terminal repeat in vitro Aids Research and Human Retroviruses. 3: 41-55. PMID 3040054 DOI: 10.1089/Aid.1987.3.41  0.305
1987 Brown M, Figge J, Hansen U, Wright C, Jeang KT, Khoury G, Livingston DM, Roberts TM. lac repressor can regulate expression from a hybrid SV40 early promoter containing a lac operator in animal cells. Cell. 49: 603-12. PMID 3034429 DOI: 10.1016/0092-8674(87)90536-8  0.388
1987 Chalifour LE, Wirak DO, Hansen U, Wassarman PM, DePamphilis ML. cis- and trans-acting sequences required for expression of simian virus 40 genes in mouse oocytes. Genes & Development. 1: 1096-106. PMID 2828165 DOI: 10.1101/Gad.1.10.1096  0.381
1987 Kim CH, Heath C, Bertuch A, Hansen U. Specific stimulation of simian virus 40 late transcription in vitro by a cellular factor binding the simian virus 40 21-base-pair repeat promoter element. Proceedings of the National Academy of Sciences of the United States of America. 84: 6025-9. PMID 2819862 DOI: 10.1073/Pnas.84.17.6025  0.437
1985 Tenen DG, Haines LL, Hansen UM, Martin RG, Livingston DM. Formation of a cruciform structure at the simian virus 40 replication origin abolishes T-antigen binding to the origin in vitro Journal of Virology. 56: 293-297. PMID 2993657 DOI: 10.1128/Jvi.56.1.293-297.1985  0.309
1983 Hansen U, Sharp PA. Sequences controlling in vitro transcription of SV40 promoters Embo Journal. 2: 2293-2303. PMID 6321158 DOI: 10.1002/J.1460-2075.1983.Tb01737.X  0.427
1981 Cepko CL, Hansen U, Handa H, Sharp PA. Sequential transcription-translation of simian virus 40 by using mammalian cell extracts. Molecular and Cellular Biology. 1: 919-31. PMID 6287212 DOI: 10.1128/Mcb.1.10.919  0.352
1981 Hansen U, Tenen DG, Livingston DM, Sharp PA. T antigen repression of SV40 early transcription from two promoters Cell. 27: 603-612. PMID 6101224 DOI: 10.1016/0092-8674(81)90402-5  0.343
1980 Hansen UM, McClure WR. Role of the sigma subunit of Escherichia coli RNA polymerase in initiation. II. Release of sigma from ternary complexes. The Journal of Biological Chemistry. 255: 9564-70. PMID 7000759  0.619
1980 Hansen UM, McClure WR. Role of the sigma subunit of Escherichia coli RNA polymerase in initiation. I. Characterization of core enzyme open complexes. The Journal of Biological Chemistry. 255: 9556-63. PMID 7000758  0.623
1979 Hansen UM, McClure WR. A noncycling activity assay for the omega subunit of Escherichia coli RNA polymerase. The Journal of Biological Chemistry. 254: 5713-7. PMID 376516  0.634
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