Trevor D. Lawley, Ph.D. - Publications

Affiliations: 
2003 University of Alberta, Edmonton, Alberta, Canada 
Area:
Microbiology Biology

86 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Cuthbertson L, Löber U, Ish-Horowicz JS, McBrien CN, Churchward C, Parker JC, Olanipekun MT, Burke C, McGowan A, Davies GA, Lewis KE, Hopkin JM, Chung KF, O'Carroll O, Faul J, ... ... Lawley TD, et al. Genomic attributes of airway commensal bacteria and mucosa. Communications Biology. 7: 171. PMID 38347162 DOI: 10.1038/s42003-024-05840-3  0.319
2022 Mäklin T, Thorpe HA, Pöntinen AK, Gladstone RA, Shao Y, Pesonen M, McNally A, Johnsen PJ, Samuelsen Ø, Lawley TD, Honkela A, Corander J. Strong pathogen competition in neonatal gut colonisation. Nature Communications. 13: 7417. PMID 36456554 DOI: 10.1038/s41467-022-35178-5  0.33
2022 Cortés A, Martin J, Rosa BA, Stark KA, Clare S, McCarthy C, Harcourt K, Brandt C, Tolley C, Lawley TD, Mitreva M, Berriman M, Rinaldi G, Cantacessi C. The gut microbial metabolic capacity of microbiome-humanized vs. wild type rodents reveals a likely dual role of intestinal bacteria in hepato-intestinal schistosomiasis. Plos Neglected Tropical Diseases. 16: e0010878. PMID 36279280 DOI: 10.1371/journal.pntd.0010878  0.565
2022 Forster SC, Liu J, Kumar N, Gulliver EL, Gould JA, Escobar-Zepeda A, Mkandawire T, Pike LJ, Shao Y, Stares MD, Browne HP, Neville BA, Lawley TD. Strain-level characterization of broad host range mobile genetic elements transferring antibiotic resistance from the human microbiome. Nature Communications. 13: 1445. PMID 35301310 DOI: 10.1038/s41467-022-29096-9  0.744
2021 Beresford-Jones BS, Forster SC, Stares MD, Notley G, Viciani E, Browne HP, Boehmler DJ, Soderholm AT, Kumar N, Vervier K, Cross JR, Almeida A, Lawley TD, Pedicord VA. The Mouse Gastrointestinal Bacteria Catalogue enables translation between the mouse and human gut microbiotas via functional mapping. Cell Host & Microbe. 30: 124-138.e8. PMID 34971560 DOI: 10.1016/j.chom.2021.12.003  0.322
2021 Mullineaux-Sanders C, Carson D, Hopkins EGD, Glegola-Madejska I, Escobar-Zepeda A, Browne HP, Lawley TD, Frankel G. Citrobacter amalonaticus Inhibits the Growth of Citrobacter rodentium in the Gut Lumen. Mbio. e0241021. PMID 34609899 DOI: 10.1128/mBio.02410-21  0.327
2021 Browne HP, Almeida A, Kumar N, Vervier K, Adoum AT, Viciani E, Dawson NJR, Forster SC, Cormie C, Goulding D, Lawley TD. Host adaptation in gut Firmicutes is associated with sporulation loss and altered transmission cycle. Genome Biology. 22: 204. PMID 34348764 DOI: 10.1186/s13059-021-02428-6  0.307
2021 Camarillo-Guerrero LF, Almeida A, Rangel-Pineros G, Finn RD, Lawley TD. Massive expansion of human gut bacteriophage diversity. Cell. 184: 1098-1109.e9. PMID 33606979 DOI: 10.1016/j.cell.2021.01.029  0.318
2021 Costa D, Lévesque S, Kumar N, Fresia P, Ferrés I, Lawley TD, Iraola G. Pangenome analysis reveals genetic isolation in Campylobacter hyointestinalis subspecies adapted to different mammalian hosts. Scientific Reports. 11: 3431. PMID 33564053 DOI: 10.1038/s41598-021-82993-9  0.317
2020 Cortés A, Clare S, Costain A, Almeida A, McCarthy C, Harcourt K, Brandt C, Tolley C, Rooney J, Berriman M, Lawley T, MacDonald AS, Rinaldi G, Cantacessi C. Baseline Gut Microbiota Composition Is Associated With Infection Burden in Rodent Models. Frontiers in Immunology. 11: 593838. PMID 33329584 DOI: 10.3389/fimmu.2020.593838  0.561
2020 Muñoz M, Guerrero-Araya E, Cortés-Tapia C, Plaza-Garrido A, Lawley TD, Paredes-Sabja D. Comprehensive genome analyses of , a potential biomarker of homeostasis gut recovery. Microbial Genomics. PMID 33206037 DOI: 10.1099/mgen.0.000476  0.336
2020 James KR, Gomes T, Elmentaite R, Kumar N, Gulliver EL, King HW, Stares MD, Bareham BR, Ferdinand JR, Petrova VN, Polański K, Forster SC, Jarvis LB, Suchanek O, Howlett S, ... ... Lawley TD, et al. Distinct microbial and immune niches of the human colon. Nature Immunology. PMID 32066951 DOI: 10.1038/S41590-020-0602-Z  0.327
2019 Shao Y, Forster SC, Tsaliki E, Vervier K, Strang A, Simpson N, Kumar N, Stares MD, Rodger A, Brocklehurst P, Field N, Lawley TD. Stunted microbiota and opportunistic pathogen colonization in caesarean-section birth. Nature. PMID 31534227 DOI: 10.1038/S41586-019-1560-1  0.403
2019 Shaw HA, Preston MD, Vendrik KEW, Cairns MD, Browne HP, Stabler RA, Crobach MJT, Corver J, Pituch H, Ingebretsen A, Primohammed M, Faulds-Pain A, Valiente E, Lawley TD, Fairweather NF, et al. "The recent emergence of a highly related virulent Clostridium difficile clade with unique characteristics". Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases. PMID 31525517 DOI: 10.1016/J.Cmi.2019.09.004  0.393
2019 Kumar N, Browne HP, Viciani E, Forster SC, Clare S, Harcourt K, Stares MD, Dougan G, Fairley DJ, Roberts P, Pirmohamed M, Clokie MRJ, Jensen MBF, Hargreaves KR, Ip M, ... ... Lawley TD, et al. Adaptation of host transmission cycle during Clostridium difficile speciation. Nature Genetics. PMID 31406348 DOI: 10.1038/S41588-019-0478-8  0.397
2019 Muñoz M, Restrepo-Montoya D, Kumar N, Iraola G, Camargo M, Díaz-Arévalo D, Roa-Molina NS, Tellez MA, Herrera G, Ríos-Chaparro DI, Birchenall C, Pinilla D, Pardo-Oviedo JM, Rodríguez-Leguizamón G, Josa DF, ... Lawley TD, et al. Integrated genomic epidemiology and phenotypic profiling of Clostridium difficile across intra-hospital and community populations in Colombia. Scientific Reports. 9: 11293. PMID 31383872 DOI: 10.1038/S41598-019-47688-2  0.429
2019 Muñoz M, Restrepo-Montoya D, Kumar N, Iraola G, Herrera G, Ríos-Chaparro DI, Díaz-Arévalo D, Patarroyo MA, Lawley TD, Ramírez JD. Comparative genomics identifies potential virulence factors in and . Virulence. 10: 657-676. PMID 31304854 DOI: 10.1080/21505594.2019.1637699  0.378
2019 Fung C, Tan S, Nakajima M, Skoog EC, Camarillo-Guerrero LF, Klein JA, Lawley TD, Solnick JV, Fukami T, Amieva MR. High-resolution mapping reveals that microniches in the gastric glands control Helicobacter pylori colonization of the stomach. Plos Biology. 17: e3000231. PMID 31048876 DOI: 10.1371/Journal.Pbio.3000231  0.633
2019 Almeida A, Mitchell AL, Boland M, Forster SC, Gloor GB, Tarkowska A, Lawley TD, Finn RD. A new genomic blueprint of the human gut microbiota. Nature. PMID 30745586 DOI: 10.1038/S41586-019-0965-1  0.448
2019 Forster SC, Kumar N, Anonye BO, Almeida A, Viciani E, Stares MD, Dunn M, Mkandawire TT, Zhu A, Shao Y, Pike LJ, Louie T, Browne HP, Mitchell AL, Neville BA, ... ... Lawley TD, et al. A human gut bacterial genome and culture collection for improved metagenomic analyses. Nature Biotechnology. 37: 186-192. PMID 30718869 DOI: 10.1038/S41587-018-0009-7  0.734
2018 Forbester JL, Lees EA, Goulding D, Forrest S, Yeung A, Speak A, Clare S, Coomber EL, Mukhopadhyay S, Kraiczy J, Schreiber F, Lawley TD, Hancock REW, Uhlig HH, Zilbauer M, et al. Interleukin-22 promotes phagolysosomal fusion to induce protection against Typhimurium in human epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 30217896 DOI: 10.1073/Pnas.1811866115  0.336
2018 Fleurbaaij F, Henneman AA, Corver J, Knetsch CW, Smits WK, Nauta ST, Giera M, Dragan I, Kumar N, Lawley TD, Verhoeven A, van Leeuwen HC, Kuijper EJ, Hensbergen PJ. Proteomic identification of Axc, a novel beta-lactamase with carbapenemase activity in a meropenem-resistant clinical isolate of Achromobacter xylosoxidans. Scientific Reports. 8: 8181. PMID 29802257 DOI: 10.1038/S41598-018-26079-Z  0.303
2018 Thomas-White K, Forster SC, Kumar N, Van Kuiken M, Putonti C, Stares MD, Hilt EE, Price TK, Wolfe AJ, Lawley TD. Culturing of female bladder bacteria reveals an interconnected urogenital microbiota. Nature Communications. 9: 1557. PMID 29674608 DOI: 10.1038/S41467-018-03968-5  0.436
2018 Collins J, Robinson C, Danhof H, Knetsch CW, van Leeuwen HC, Lawley TD, Auchtung JM, Britton RA. Dietary trehalose enhances virulence of epidemic Clostridium difficile. Nature. PMID 29310122 DOI: 10.1038/Nature25178  0.362
2017 Knetsch CW, Kumar N, Forster SC, Connor TR, Browne HP, Harmanus C, Sanders IM, Harris SR, Turner L, Morris T, Perry M, Miyajima F, Roberts P, Pirmohamed M, Songer JG, ... ... Lawley TD, et al. Zoonotic transfer of Clostridium difficile harboring antimicrobial resistance between farm animals and humans. Journal of Clinical Microbiology. PMID 29237792 DOI: 10.1128/Jcm.01384-17  0.416
2017 Iraola G, Forster SC, Kumar N, Lehours P, Bekal S, García-Peña FJ, Paolicchi F, Morsella C, Hotzel H, Hsueh PR, Vidal A, Lévesque S, Yamazaki W, Balzan C, Vargas A, ... ... Lawley TD, et al. Distinct Campylobacter fetus lineages adapted as livestock pathogens and human pathobionts in the intestinal microbiota. Nature Communications. 8: 1367. PMID 29118316 DOI: 10.1038/S41467-017-01449-9  0.417
2017 Neville BA, Forster SC, Lawley TD. Commensal Koch's postulates: establishing causation in human microbiota research. Current Opinion in Microbiology. 42: 47-52. PMID 29112885 DOI: 10.1016/J.Mib.2017.10.001  0.408
2017 Ruiz L, Bottacini F, Boinett CJ, Cain AK, O'Connell-Motherway M, Lawley TD, van Sinderen D. The essential genomic landscape of the commensal Bifidobacterium breve UCC2003. Scientific Reports. 7: 5648. PMID 28717159 DOI: 10.1038/S41598-017-05795-Y  0.414
2017 Browne HP, Neville BA, Forster SC, Lawley TD. Transmission of the gut microbiota: spreading of health. Nature Reviews. Microbiology. PMID 28603278 DOI: 10.1038/Nrmicro.2017.50  0.419
2016 O Sheridan P, Martin JC, Lawley TD, Browne HP, Harris HM, Bernalier-Donadille A, Duncan SH, O'Toole PW, P Scott K, J Flint H. Polysaccharide utilization loci and nutritional specialization in a dominant group of butyrate-producing human colonic Firmicutes. Microbial Genomics. 2: e000043. PMID 28348841 DOI: 10.1099/mgen.0.000043  0.307
2016 Cairns MD, Preston MD, Hall CL, Gerding DN, Hawkey PM, Kato H, Kim H, Kuijper EJ, Lawley TD, Pituch H, Reid S, Kullin B, Riley TV, Solomon K, Tsai PJ, et al. Comparative genome analysis and global phylogeny of the toxin variant Clostridium difficile PCR Ribotype 017 reveals the evolution of two independent sub-lineages. Journal of Clinical Microbiology. PMID 28031436 DOI: 10.1128/Jcm.01296-16  0.422
2016 Wagner J, Coupland P, Browne HP, Lawley TD, Francis SC, Parkhill J. Evaluation of PacBio sequencing for full-length bacterial 16S rRNA gene classification. Bmc Microbiology. 16: 274. PMID 27842515 DOI: 10.1186/S12866-016-0891-4  0.391
2016 Browne HP, Forster SC, Anonye BO, Kumar N, Neville BA, Stares MD, Goulding D, Lawley TD. Culturing of 'unculturable' human microbiota reveals novel taxa and extensive sporulation. Nature. PMID 27144353 DOI: 10.1038/Nature17645  0.446
2016 Fung TC, Bessman NJ, Hepworth MR, Kumar N, Shibata N, Kobuley D, Wang K, Ziegler CG, Goc J, Shima T, Umesaki Y, Sartor RB, Sullivan KV, Lawley TD, Kunisawa J, et al. Lymphoid-Tissue-Resident Commensal Bacteria Promote Members of the IL-10 Cytokine Family to Establish Mutualism. Immunity. 44: 634-646. PMID 26982365 DOI: 10.1016/J.Immuni.2016.02.019  0.306
2016 Quesada-Gómez C, López-Ureña D, Chumbler N, Kroh HK, Castro-Peña C, Rodríguez C, Orozco-Aguilar J, González-Camacho S, Rucavado A, Guzmán-Verri C, Lawley TD, Lacy DB, Chaves-Olarte E. Analysis of TcdBs within the hypervirulent clade 2 reveals an impact of RhoA glucosylation in Clostridium difficile pro inflammatory activities. Infection and Immunity. PMID 26755157 DOI: 10.1128/Iai.01291-15  0.365
2016 Robilotti E, Kumar N, Banaei N, Lawley T, Tompkins L. Analysis of Inpatient Clostridium difficile (CD) Transmission by Traditional Genotyping and Whole Genome Phylogeny Open Forum Infectious Diseases. 3. DOI: 10.1093/Ofid/Ofw194.49  0.579
2015 Kumar N, Miyajima F, He M, Roberts P, Swale A, Ellison L, Pickard D, Smith G, Molyneux R, Dougan G, Parkhill J, Wren BW, Parry CM, Pirmohamed M, Lawley TD. Genome-based infection tracking reveals dynamics of Clostridium difficile transmission and disease recurrence. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 26683317 DOI: 10.1093/Cid/Civ1031  0.388
2015 Forster SC, Browne HP, Kumar N, Hunt M, Denise H, Mitchell A, Finn RD, Lawley TD. HPMCD: the database of human microbial communities from metagenomic datasets and microbial reference genomes. Nucleic Acids Research. PMID 26578596 DOI: 10.1093/Nar/Gkv1216  0.399
2015 Hoy YE, Bik EM, Lawley TD, Holmes SP, Monack DM, Theriot JA, Relman DA. Variation in Taxonomic Composition of the Fecal Microbiota in an Inbred Mouse Strain across Individuals and Time. Plos One. 10: e0142825. PMID 26565698 DOI: 10.1371/Journal.Pone.0142825  0.722
2015 Schreiber F, Arasteh JM, Lawley TD. Pathogen Resistance Mediated by IL-22 Signaling at the Epithelial-Microbiota Interface. Journal of Molecular Biology. 427: 3676-82. PMID 26497621 DOI: 10.1016/J.Jmb.2015.10.013  0.346
2015 Cairns MD, Preston MD, Lawley TD, Clark TG, Stabler RA, Wren BW. Genomic Epidemiology of a Protracted Hospital Outbreak Caused by a Toxin A-Negative Clostridium difficile Sublineage PCR Ribotype 017 Strain in London, England. Journal of Clinical Microbiology. 53: 3141-7. PMID 26179308 DOI: 10.1128/Jcm.00648-15  0.366
2015 Carter GP, Chakravorty A, Pham Nguyen TA, Mileto S, Schreiber F, Li L, Howarth P, Clare S, Cunningham B, Sambol SP, Cheknis A, Figueroa I, Johnson S, Gerding D, Rood JI, ... ... Lawley TD, et al. Defining the Roles of TcdA and TcdB in Localized Gastrointestinal Disease, Systemic Organ Damage, and the Host Response during Clostridium difficile Infections. Mbio. 6. PMID 26037121 DOI: 10.1128/Mbio.00551-15  0.411
2015 Hargreaves KR, Otieno JR, Thanki A, Blades MJ, Millard AD, Browne HP, Lawley TD, Clokie MR. As Clear as Mud? Determining the Diversity and Prevalence of Prophages in the Draft Genomes of Estuarine Isolates of Clostridium difficile. Genome Biology and Evolution. 7: 1842-55. PMID 26019165 DOI: 10.1093/Gbe/Evv094  0.413
2015 Couchman EC, Browne HP, Dunn M, Lawley TD, Songer JG, Hall V, Petrovska L, Vidor C, Awad M, Lyras D, Fairweather NF. Clostridium sordellii genome analysis reveals plasmid localized toxin genes encoded within pathogenicity loci. Bmc Genomics. 16: 392. PMID 25981746 DOI: 10.1186/S12864-015-1613-2  0.444
2015 Gebhart D, Lok S, Clare S, Tomas M, Stares M, Scholl D, Donskey CJ, Lawley TD, Govoni GR. A modified R-type bacteriocin specifically targeting Clostridium difficile prevents colonization of mice without affecting gut microbiota diversity. Mbio. 6. PMID 25805733 DOI: 10.1128/Mbio.02368-14  0.387
2015 Dembek M, Barquist L, Boinett CJ, Cain AK, Mayho M, Lawley TD, Fairweather NF, Fagan RP. High-throughput analysis of gene essentiality and sporulation in Clostridium difficile. Mbio. 6: e02383. PMID 25714712 DOI: 10.1128/Mbio.02383-14  0.434
2015 Browne HP, Anvar SY, Frank J, Lawley TD, Roberts AP, Smits WK. Complete genome sequence of BS49 and draft genome sequence of BS34A, Bacillus subtilis strains carrying Tn916. Fems Microbiology Letters. 362: 1-4. PMID 25673660 DOI: 10.1093/Femsle/Fnu050  0.385
2015 Quesada-Gómez C, López-Ureña D, Acuña-Amador L, Villalobos-Zúñiga M, Du T, Freire R, Guzmán-Verri C, del Mar Gamboa-Coronado M, Lawley TD, Moreno E, Mulvey MR, de Castro Brito GA, Rodríguez-Cavallini E, Rodríguez C, Chaves-Olarte E. Emergence of an outbreak-associated Clostridium difficile variant with increased virulence. Journal of Clinical Microbiology. 53: 1216-26. PMID 25653402 DOI: 10.1128/Jcm.03058-14  0.393
2015 Forster SC, Lawley TD. Systematic discovery of probiotics. Nature Biotechnology. 33: 47-9. PMID 25574637 DOI: 10.1038/Nbt.3111  0.324
2014 Pham N TA, Lawley TD. Pathogens' exploitation of the intestinal food web. Cell Host & Microbe. 16: 703-5. PMID 25498340 DOI: 10.1016/J.Chom.2014.11.012  0.313
2014 Knetsch CW, Connor TR, Mutreja A, van Dorp SM, Sanders IM, Browne HP, Harris D, Lipman L, Keessen EC, Corver J, Kuijper EJ, Lawley TD. Whole genome sequencing reveals potential spread of Clostridium difficile between humans and farm animals in the Netherlands, 2002 to 2011. Euro Surveillance : Bulletin Europeen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin. 19: 20954. PMID 25411691 DOI: 10.2807/1560-7917.Es2014.19.45.20954  0.401
2014 Pham TA, Clare S, Goulding D, Arasteh JM, Stares MD, Browne HP, Keane JA, Page AJ, Kumasaka N, Kane L, Mottram L, Harcourt K, Hale C, Arends MJ, Gaffney DJ, ... ... Lawley TD, et al. Epithelial IL-22RA1-mediated fucosylation promotes intestinal colonization resistance to an opportunistic pathogen. Cell Host & Microbe. 16: 504-16. PMID 25263220 DOI: 10.1016/J.Chom.2014.08.017  0.399
2014 Hargreaves KR, Flores CO, Lawley TD, Clokie MR. Abundant and diverse clustered regularly interspaced short palindromic repeat spacers in Clostridium difficile strains and prophages target multiple phage types within this pathogen. Mbio. 5: e01045-13. PMID 25161187 DOI: 10.1128/Mbio.01045-13  0.466
2014 Pham TA, Lawley TD. Emerging insights on intestinal dysbiosis during bacterial infections. Current Opinion in Microbiology. 17: 67-74. PMID 24581695 DOI: 10.1016/J.Mib.2013.12.002  0.462
2014 Pettit LJ, Browne HP, Yu L, Smits WK, Fagan RP, Barquist L, Martin MJ, Goulding D, Duncan SH, Flint HJ, Dougan G, Choudhary JS, Lawley TD. Functional genomics reveals that Clostridium difficile Spo0A coordinates sporulation, virulence and metabolism. Bmc Genomics. 15: 160. PMID 24568651 DOI: 10.1186/1471-2164-15-160  0.463
2013 Lawley TD, Young VB. Murine models to study Clostridium difficile infection and transmission. Anaerobe. 24: 94-7. PMID 24076318 DOI: 10.1016/J.Anaerobe.2013.09.008  0.363
2013 Fimlaid KA, Bond JP, Schutz KC, Putnam EE, Leung JM, Lawley TD, Shen A. Global analysis of the sporulation pathway of Clostridium difficile. Plos Genetics. 9: e1003660. PMID 23950727 DOI: 10.1371/Journal.Pgen.1003660  0.352
2013 Iraola G, Pérez R, Naya H, Paolicchi F, Harris D, Lawley TD, Rego N, Hernández M, Calleros L, Carretto L, Velilla A, Morsella C, Méndez A, Gioffre A. Complete Genome Sequence of Campylobacter fetus subsp. venerealis Biovar Intermedius, Isolated from the Prepuce of a Bull. Genome Announcements. 1. PMID 23908278 DOI: 10.1128/Genomea.00526-13  0.363
2013 Adamu BO, Lawley TD. Bacteriotherapy for the treatment of intestinal dysbiosis caused by Clostridium difficile infection. Current Opinion in Microbiology. 16: 596-601. PMID 23866975 DOI: 10.1016/J.Mib.2013.06.009  0.384
2013 Martin MJ, Clare S, Goulding D, Faulds-Pain A, Barquist L, Browne HP, Pettit L, Dougan G, Lawley TD, Wren BW. The agr locus regulates virulence and colonization genes in Clostridium difficile 027. Journal of Bacteriology. 195: 3672-81. PMID 23772065 DOI: 10.1128/Jb.00473-13  0.399
2013 Knetsch CW, Lawley TD, Hensgens MP, Corver J, Wilcox MW, Kuijper EJ. Current application and future perspectives of molecular typing methods to study Clostridium difficile infections. Euro Surveillance : Bulletin EuropéEn Sur Les Maladies Transmissibles = European Communicable Disease Bulletin. 18: 20381. PMID 23369393 DOI: 10.2807/Ese.18.04.20381-En  0.348
2013 Chen JW, Scaria J, Mao C, Sobral B, Zhang S, Lawley T, Chang YF. Proteomic comparison of historic and recently emerged hypervirulent Clostridium difficile strains. Journal of Proteome Research. 12: 1151-61. PMID 23298230 DOI: 10.1021/Pr3007528  0.329
2013 Putnam EE, Nock AM, Lawley TD, Shen A. SpoIVA and SipL are Clostridium difficile spore morphogenetic proteins. Journal of Bacteriology. 195: 1214-25. PMID 23292781 DOI: 10.1128/Jb.02181-12  0.34
2013 Lawley TD, Walker AW. Intestinal colonization resistance. Immunology. 138: 1-11. PMID 23240815 DOI: 10.1111/J.1365-2567.2012.03616.X  0.394
2013 He M, Miyajima F, Roberts P, Ellison L, Pickard DJ, Martin MJ, Connor TR, Harris SR, Fairley D, Bamford KB, D'Arc S, Brazier J, Brown D, Coia JE, Douce G, ... ... Lawley TD, et al. Emergence and global spread of epidemic healthcare-associated Clostridium difficile. Nature Genetics. 45: 109-13. PMID 23222960 DOI: 10.1038/Ng.2478  0.351
2013 Walker AW, Lawley TD. Therapeutic modulation of intestinal dysbiosis. Pharmacological Research. 69: 75-86. PMID 23017673 DOI: 10.1016/J.Phrs.2012.09.008  0.379
2013 Field N, Townsend CL, Rodger AJ, Lawley TD, Riley EM, Brocklehurst P. Infection and immunity from a lifecourse perspective: Life Study Enhancement The Lancet. 382: S35. DOI: 10.1016/S0140-6736(13)62460-5  0.338
2012 Lawley TD, Clare S, Walker AW, Stares MD, Connor TR, Raisen C, Goulding D, Rad R, Schreiber F, Brandt C, Deakin LJ, Pickard DJ, Duncan SH, Flint HJ, Clark TG, et al. Targeted restoration of the intestinal microbiota with a simple, defined bacteriotherapy resolves relapsing Clostridium difficile disease in mice. Plos Pathogens. 8: e1002995. PMID 23133377 DOI: 10.1371/Journal.Ppat.1002995  0.406
2012 Kos VN, Desjardins CA, Griggs A, Cerqueira G, Van Tonder A, Holden MT, Godfrey P, Palmer KL, Bodi K, Mongodin EF, Wortman J, Feldgarden M, Lawley T, Gill SR, Haas BJ, et al. Comparative genomics of vancomycin-resistant Staphylococcus aureus strains and their positions within the clade most commonly associated with Methicillin-resistant S. aureus hospital-acquired infection in the United States. Mbio. 3. PMID 22617140 DOI: 10.1128/Mbio.00112-12  0.385
2012 Deakin LJ, Clare S, Fagan RP, Dawson LF, Pickard DJ, West MR, Wren BW, Fairweather NF, Dougan G, Lawley TD. The Clostridium difficile spo0A gene is a persistence and transmission factor. Infection and Immunity. 80: 2704-11. PMID 22615253 DOI: 10.1128/Iai.00147-12  0.433
2012 Mullany P, Williams R, Langridge GC, Turner DJ, Whalan R, Clayton C, Lawley T, Hussain H, McCurrie K, Morden N, Allan E, Roberts AP. Behavior and target site selection of conjugative transposon Tn916 in two different strains of toxigenic Clostridium difficile Applied and Environmental Microbiology. 78: 2147-2153. PMID 22267673 DOI: 10.1128/Aem.06193-11  0.388
2011 Arnold IC, Zigova Z, Holden M, Lawley TD, Rad R, Dougan G, Falkow S, Bentley SD, Müller A. Comparative whole genome sequence analysis of the carcinogenic bacterial model pathogen Helicobacter felis. Genome Biology and Evolution. 3: 302-8. PMID 21402865 DOI: 10.1093/Gbe/Evr022  0.637
2010 Lawley TD, Clare S, Deakin LJ, Goulding D, Yen JL, Raisen C, Brandt C, Lovell J, Cooke F, Clark TG, Dougan G. Use of purified Clostridium difficile spores to facilitate evaluation of health care disinfection regimens. Applied and Environmental Microbiology. 76: 6895-900. PMID 20802075 DOI: 10.1128/Aem.00718-10  0.325
2010 He M, Sebaihia M, Lawley TD, Stabler RA, Dawson LF, Martin MJ, Holt KE, Seth-Smith HM, Quail MA, Rance R, Brooks K, Churcher C, Harris D, Bentley SD, Burrows C, et al. Evolutionary dynamics of Clostridium difficile over short and long time scales. Proceedings of the National Academy of Sciences of the United States of America. 107: 7527-32. PMID 20368420 DOI: 10.1073/Pnas.0914322107  0.412
2009 Stabler RA, He M, Dawson L, Martin M, Valiente E, Corton C, Lawley TD, Sebaihia M, Quail MA, Rose G, Gerding DN, Gibert M, Popoff MR, Parkhill J, Dougan G, et al. Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium. Genome Biology. 10: R102. PMID 19781061 DOI: 10.1186/Gb-2009-10-9-R102  0.419
2009 Lawley TD, Clare S, Walker AW, Goulding D, Stabler RA, Croucher N, Mastroeni P, Scott P, Raisen C, Mottram L, Fairweather NF, Wren BW, Parkhill J, Dougan G. Antibiotic treatment of clostridium difficile carrier mice triggers a supershedder state, spore-mediated transmission, and severe disease in immunocompromised hosts. Infection and Immunity. 77: 3661-9. PMID 19564382 DOI: 10.1128/Iai.00558-09  0.418
2009 Lawley TD, Croucher NJ, Yu L, Clare S, Sebaihia M, Goulding D, Pickard DJ, Parkhill J, Choudhary J, Dougan G. Proteomic and genomic characterization of highly infectious Clostridium difficile 630 spores. Journal of Bacteriology. 191: 5377-86. PMID 19542279 DOI: 10.1128/Jb.00597-09  0.375
2008 Lawley TD, Bouley DM, Hoy YE, Gerke C, Relman DA, Monack DM. Host transmission of Salmonella enterica serovar Typhimurium is controlled by virulence factors and indigenous intestinal microbiota. Infection and Immunity. 76: 403-16. PMID 17967858 DOI: 10.1128/Iai.01189-07  0.748
2006 Lawley TD, Chan K, Thompson LJ, Kim CC, Govoni GR, Monack DM. Genome-wide screen for Salmonella genes required for long-term systemic infection of the mouse. Plos Pathogens. 2: e11. PMID 16518469 DOI: 10.1371/Journal.Ppat.0020011  0.749
2003 Lawley TD, Klimke WA, Gubbins MJ, Frost LS. F factor conjugation is a true type IV secretion system. Fems Microbiology Letters. 224: 1-15. PMID 12855161 DOI: 10.1016/S0378-1097(03)00430-0  0.694
2003 Lawley TD, Gilmour MW, Gunton JE, Tracz DM, Taylor DE. Functional and mutational analysis of conjugative transfer region 2 (Tra2) from the IncHI1 plasmid R27. Journal of Bacteriology. 185: 581-91. PMID 12511505 DOI: 10.1128/Jb.185.2.581-591.2003  0.302
2002 Lawley TD, Gilmour MW, Gunton JE, Standeven LJ, Taylor DE. Functional and mutational analysis of conjugative transfer region 1 (Tra1) from the IncHI1 plasmid R27. Journal of Bacteriology. 184: 2173-80. PMID 11914349 DOI: 10.1128/Jb.184.8.2173-2180.2002  0.313
2000 Lawley TD, Burland V, Taylor DE. Analysis of the complete nucleotide sequence of the tetracycline- resistance transposon Tn10 Plasmid. 43: 235-239. PMID 10783303 DOI: 10.1006/Plas.1999.1458  0.313
2000 Sherburne CK, Lawley TD, Gilmour MW, Blattner FR, Burland V, Grotbeck E, Rose DJ, Taylor DE. The complete DNA sequence and analysis of R27, a large IncHI plasmid from Salmonella typhi that is temperature sensitive for transfer. Nucleic Acids Research. 28: 2177-86. PMID 10773089 DOI: 10.1093/Nar/28.10.2177  0.346
1999 Rooker MM, Sherburne C, Lawley TD, Taylor DE. Characterization of the Tra2 region of the incHI1 plasmid R27 Plasmid. 41: 226-239. PMID 10366528 DOI: 10.1006/Plas.1999.1396  0.318
1999 Taylor DE, Newnham PJ, Sherburne C, Lawley TD, Rooker MM. Sequencing and characterization of Salmonella typhi plasmid R27 (incompatibility group HI1) trhC, a transfer gene encoding a potential nucleoside triphosphate-binding domain Plasmid. 41: 207-218. PMID 10366526 DOI: 10.1006/Plas.1999.1394  0.343
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