Alan D. Frankel - Publications

Affiliations: 
University of California, San Francisco, San Francisco, CA 
Area:
Biochemistry

119 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Li Y, Liu X, Fujinaga K, Gross JD, Frankel AD. Enhanced NF-κB activation via HIV-1 Tat-TRAF6 cross-talk. Science Advances. 10: eadi4162. PMID 38241362 DOI: 10.1126/sciadv.adi4162  0.324
2022 Safari M, Jayaraman B, Yang S, Smith C, Fernandes JD, Frankel AD. Functional and structural segregation of overlapping helices in HIV-1. Elife. 11. PMID 35511220 DOI: 10.7554/eLife.72482  0.792
2020 Carlson CR, Asfaha JB, Ghent CM, Howard CJ, Hartooni N, Safari M, Frankel AD, Morgan DO. Phosphoregulation of Phase Separation by the SARS-CoV-2 N Protein Suggests a Biophysical Basis for its Dual Functions. Molecular Cell. PMID 33248025 DOI: 10.1016/j.molcel.2020.11.025  0.814
2020 Gordon DE, Jang GM, Bouhaddou M, Xu J, Obernier K, White KM, O'Meara MJ, Rezelj VV, Guo JZ, Swaney DL, Tummino TA, Huettenhain R, Kaake RM, Richards AL, Tutuncuoglu B, ... ... Frankel AD, et al. A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. Nature. PMID 32353859 DOI: 10.1038/S41586-020-2286-9  0.761
2020 Gordon DE, Watson A, Roguev A, Zheng S, Jang GM, Kane J, Xu J, Guo JZ, Stevenson E, Swaney DL, Franks-Skiba K, Verschueren E, Shales M, Crosby DC, Frankel AD, et al. A Quantitative Genetic Interaction Map of HIV Infection. Molecular Cell. PMID 32084337 DOI: 10.1016/J.Molcel.2020.02.004  0.364
2019 Hüttenhain R, Xu J, Burton LA, Gordon DE, Hultquist JF, Johnson JR, Satkamp L, Hiatt J, Rhee DY, Baek K, Crosby DC, Frankel AD, Marson A, Harper JW, Alpi AF, et al. ARIH2 Is a Vif-Dependent Regulator of CUL5-Mediated APOBEC3G Degradation in HIV Infection. Cell Host & Microbe. PMID 31253590 DOI: 10.1016/J.Chom.2019.05.008  0.353
2019 Jayaraman B, Fernandes JD, Yang S, Smith C, Frankel AD. Highly Mutable Linker Regions Regulate HIV-1 Rev Function and Stability. Scientific Reports. 9: 5139. PMID 30914719 DOI: 10.1038/S41598-019-41582-7  0.742
2018 Dai Y, Wynn J, Peralta A, Sherpa C, Jayaraman B, Li H, Verma A, Frankel AD, Le Grice SFJ, Santos WL. Discovery of a Branched Peptide that Recognizes the Rev Response Element (RRE) RNA and Blocks HIV-1 Replication. Journal of Medicinal Chemistry. PMID 30289719 DOI: 10.1021/Acs.Jmedchem.8B01076  0.714
2018 Faust TB, Li Y, Bacon CW, Jang GM, Weiss A, Jayaraman B, Newton BW, Krogan NJ, D'Orso I, Frankel AD. The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation. Elife. 7. PMID 29845934 DOI: 10.7554/Elife.31879  0.662
2018 Faust TB, Li Y, Bacon CW, Jang GM, Weiss A, Jayaraman B, Newton BW, Krogan NJ, D'Orso I, Frankel AD. Author response: The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation Elife. DOI: 10.7554/Elife.31879.027  0.641
2017 Faust TB, Binning JM, Gross JD, Frankel AD. Making Sense of Multifunctional Proteins: Human Immunodeficiency Virus Type 1 Accessory and Regulatory Proteins and Connections to Transcription. Annual Review of Virology. 4: 241-260. PMID 28961413 DOI: 10.1146/Annurev-Virology-101416-041654  0.457
2017 Nakamura RL, Burlingame MA, Yang S, Crosby DC, Talbot DJ, Chui K, Frankel AD, Renslo AR. Identification and optimization of thienopyridine carboxamides as inhibitors of HIV regulatory complexes. Antimicrobial Agents and Chemotherapy. PMID 28416550 DOI: 10.1128/Aac.02366-16  0.789
2017 Faust TB, Li Y, Jang GM, Johnson JR, Yang S, Weiss A, Krogan NJ, Frankel AD. PJA2 ubiquitinates the HIV-1 Tat protein with atypical chain linkages to activate viral transcription. Scientific Reports. 7: 45394. PMID 28345603 DOI: 10.1038/Srep45394  0.511
2016 Fernandes JD, Faust TB, Strauli NB, Smith C, Crosby DC, Nakamura RL, Hernandez RD, Frankel AD. Functional Segregation of Overlapping Genes in HIV. Cell. 167: 1762-1773.e12. PMID 27984726 DOI: 10.1016/J.Cell.2016.11.031  0.785
2016 Jayaraman B, Smith AM, Fernandes JD, Frankel AD. Oligomeric viral proteins: small in size, large in presence. Critical Reviews in Biochemistry and Molecular Biology. 1-16. PMID 27685368 DOI: 10.1080/10409238.2016.1215406  0.793
2016 Fernandes JD, Booth DS, Frankel AD. A structurally plastic ribonuceloprotein complex mediates post-transcriptional gene regulation in HIV-1. Wiley Interdisciplinary Reviews. Rna. PMID 26929078 DOI: 10.1002/Wrna.1342  0.821
2015 Jayaraman B, Mavor D, Gross JD, Frankel AD. Thermodynamics of Rev-RNA Interactions in HIV-1 Rev-RRE Assembly. Biochemistry. 54: 6545-54. PMID 26422686 DOI: 10.1021/Acs.Biochem.5B00876  0.698
2015 Dunyak BM, Nakamura RL, Frankel AD, Gestwicki JE. Selective Targeting of Cells via Bispecific Molecules That Exploit Coexpression of Two Intracellular Proteins. Acs Chemical Biology. PMID 26322864 DOI: 10.1021/Acschembio.5B00426  0.762
2014 Booth DS, Cheng Y, Frankel AD. The export receptor Crm1 forms a dimer to promote nuclear export of HIV RNA. Elife. 3: e04121. PMID 25486595 DOI: 10.7554/Elife.04121  0.79
2014 Jayaraman B, Crosby DC, Homer C, Ribeiro I, Mavor D, Frankel AD. RNA-directed remodeling of the HIV-1 protein Rev orchestrates assembly of the Rev-Rev response element complex. Elife. 3: e04120. PMID 25486594 DOI: 10.7554/Elife.04120  0.729
2014 Booth DS, Cheng Y, Frankel AD. Author response: The export receptor Crm1 forms a dimer to promote nuclear export of HIV RNA Elife. DOI: 10.7554/Elife.04121.016  0.757
2014 Jayaraman B, Crosby DC, Homer C, Ribeiro I, Mavor D, Frankel AD. Author response: RNA-directed remodeling of the HIV-1 protein Rev orchestrates assembly of the Rev–Rev response element complex Elife. DOI: 10.7554/Elife.04120.020  0.673
2012 Nakamura RL, Landt SG, Mai E, Nejim J, Chen L, Frankel AD. A cell-based method for screening RNA-protein interactions: identification of constitutive transport element-interacting proteins. Plos One. 7: e48194. PMID 23133567 DOI: 10.1371/Journal.Pone.0048194  0.823
2012 D'Orso I, Jang GM, Pastuszak AW, Faust TB, Quezada E, Booth DS, Frankel AD. Transition step during assembly of HIV Tat:P-TEFb transcription complexes and transfer to TAR RNA. Molecular and Cellular Biology. 32: 4780-93. PMID 23007159 DOI: 10.1128/Mcb.00206-12  0.744
2012 Fernandes J, Jayaraman B, Frankel A. The HIV-1 Rev response element: an RNA scaffold that directs the cooperative assembly of a homo-oligomeric ribonucleoprotein complex. Rna Biology. 9: 6-11. PMID 22258145 DOI: 10.4161/Rna.9.1.18178  0.795
2012 Jäger S, Cimermancic P, Gulbahce N, Johnson JR, McGovern KE, Clarke SC, Shales M, Mercenne G, Pache L, Li K, Hernandez H, Jang GM, Roth SL, Akiva E, Marlett J, ... ... Frankel AD, et al. Global landscape of HIV-human protein complexes. Nature. 481: 365-70. PMID 22190034 DOI: 10.1038/Nature10719  0.701
2011 Fahey ME, Bennett MJ, Mahon C, Jäger S, Pache L, Kumar D, Shapiro A, Rao K, Chanda SK, Craik CS, Frankel AD, Krogan NJ. GPS-Prot: a web-based visualization platform for integrating host-pathogen interaction data. Bmc Bioinformatics. 12: 298. PMID 21777475 DOI: 10.1186/1471-2105-12-298  0.367
2011 Pastuszak AW, Joachimiak MP, Blanchette M, Rio DC, Brenner SE, Frankel AD. An SF1 affinity model to identify branch point sequences in human introns. Nucleic Acids Research. 39: 2344-56. PMID 21071404 DOI: 10.1093/Nar/Gkq1046  0.582
2011 Jäger S, Gulbahce N, Cimermancic P, Kane J, He N, Chou S, D'Orso I, Fernandes J, Jang G, Frankel AD, Alber T, Zhou Q, Krogan NJ. Purification and characterization of HIV-human protein complexes. Methods (San Diego, Calif.). 53: 13-9. PMID 20708689 DOI: 10.1016/J.Ymeth.2010.08.007  0.678
2010 D'Orso I, Frankel AD. HIV-1 Tat: Its Dependence on Host Factors is Crystal Clear. Viruses. 2: 2226-2234. PMID 21709748 DOI: 10.3390/V2102226  0.38
2010 Wang H, Ma X, Yeh YS, Zhu Y, Daugherty MD, Frankel AD, Musier-Forsyth K, Barbara PF. Comparative analysis of RNA/protein dynamics for the arginine-rich-binding motif and zinc-finger-binding motif proteins encoded by HIV-1. Biophysical Journal. 99: 3454-62. PMID 21081095 DOI: 10.1016/J.Bpj.2010.09.051  0.787
2010 Daugherty MD, Liu B, Frankel AD. Structural basis for cooperative RNA binding and export complex assembly by HIV Rev. Nature Structural & Molecular Biology. 17: 1337-42. PMID 20953181 DOI: 10.1038/Nsmb.1902  0.786
2010 Daugherty MD, Booth DS, Jayaraman B, Cheng Y, Frankel AD. HIV Rev response element (RRE) directs assembly of the Rev homooligomer into discrete asymmetric complexes. Proceedings of the National Academy of Sciences of the United States of America. 107: 12481-6. PMID 20616058 DOI: 10.1073/Pnas.1007022107  0.834
2010 D'Orso I, Frankel AD. RNA-mediated displacement of an inhibitory snRNP complex activates transcription elongation. Nature Structural & Molecular Biology. 17: 815-21. PMID 20562857 DOI: 10.1038/Nsmb.1827  0.474
2009 Bushman FD, Malani N, Fernandes J, D'Orso I, Cagney G, Diamond TL, Zhou H, Hazuda DJ, Espeseth AS, König R, Bandyopadhyay S, Ideker T, Goff SP, Krogan NJ, Frankel AD, et al. Host cell factors in HIV replication: meta-analysis of genome-wide studies. Plos Pathogens. 5: e1000437. PMID 19478882 DOI: 10.1371/Journal.Ppat.1000437  0.663
2009 D'Orso I, Frankel AD. Tat acetylation modulates assembly of a viral-host RNA-protein transcription complex. Proceedings of the National Academy of Sciences of the United States of America. 106: 3101-6. PMID 19223581 DOI: 10.1073/Pnas.0900012106  0.565
2009 Yeh Y, Wang H, Barbara PF, Daugherty MD, Frankel AD, Musier-Forsyth K. Nucleocapsid Protein Locally Melts The Iib Region Of Hiv-1 Rre Rna, But Rev Protein Does Not: A Single-molecule Spectroscopic Study Biophysical Journal. 96: 292a. DOI: 10.1016/J.Bpj.2008.12.1446  0.789
2008 Daugherty MD, D'Orso I, Frankel AD. A solution to limited genomic capacity: using adaptable binding surfaces to assemble the functional HIV Rev oligomer on RNA. Molecular Cell. 31: 824-34. PMID 18922466 DOI: 10.1016/J.Molcel.2008.07.016  0.776
2008 D'Orso I, Grunwell JR, Nakamura RL, Das C, Frankel AD. Targeting tat inhibitors in the assembly of human immunodeficiency virus type 1 transcription complexes. Journal of Virology. 82: 9492-504. PMID 18667497 DOI: 10.1128/Jvi.00763-08  0.801
2008 Mokdad A, Frankel AD. ISFOLD: Structure prediction of base pairs in non-helical RNA motifs from isostericity signatures in their sequence alignments Journal of Biomolecular Structure and Dynamics. 25: 467-472. PMID 18282001 DOI: 10.1080/07391102.2008.10531239  0.369
2006 Mills NL, Daugherty MD, Frankel AD, Guy RK. An alpha-helical peptidomimetic inhibitor of the HIV-1 Rev-RRE interaction. Journal of the American Chemical Society. 128: 3496-7. PMID 16536504 DOI: 10.1021/ja0582051  0.731
2005 Calabro V, Frankel AD. Viral RNA gymnastics. Nature Chemical Biology. 1: 67-8. PMID 16407998 DOI: 10.1038/Nchembio0705-67  0.445
2005 Landt SG, Ramirez A, Daugherty MD, Frankel AD. A simple motif for protein recognition in DNA secondary structures. Journal of Molecular Biology. 351: 982-94. PMID 16055152 DOI: 10.1016/J.Jmb.2005.07.001  0.825
2005 Calabro V, Daugherty MD, Frankel AD. A single intermolecular contact mediates intramolecular stabilization of both RNA and protein. Proceedings of the National Academy of Sciences of the United States of America. 102: 6849-54. PMID 15857951 DOI: 10.1073/Pnas.0409282102  0.77
2005 Landt SG, Tipton AR, Frankel AD. Localized influence of 2'-hydroxyl groups and helix geometry on protein recognition in the RNA major groove. Biochemistry. 44: 6547-58. PMID 15850388 DOI: 10.1021/Bi047916T  0.841
2004 Das C, Edgcomb SP, Peteranderl R, Chen L, Frankel AD. Evidence for conformational flexibility in the Tat-TAR recognition motif of cyclin T1. Virology. 318: 306-17. PMID 14972556 DOI: 10.1016/J.Virol.2003.10.003  0.813
2004 Xie B, Calabro V, Wainberg MA, Frankel AD. Selection of TAR RNA-binding chameleon peptides by using a retroviral replication system. Journal of Virology. 78: 1456-63. PMID 14722301 DOI: 10.1128/Jvi.78.3.1456-1463.2004  0.57
2004 Cheng AC, Frankel AD. Ab initio interaction energies of hydrogen-bonded amino acid side chain[bond]nucleic acid base interactions. Journal of the American Chemical Society. 126: 434-5. PMID 14719918 DOI: 10.1021/Ja037264G  0.627
2003 Das C, Frankel AD. Sequence and structure space of RNA-binding peptides. Biopolymers. 70: 80-5. PMID 12925994 DOI: 10.1002/Bip.10429  0.796
2003 Harada K, Horiya S, Zehavi H, Frankel AD. Screening in vivo for RNA-binding peptides from combinatorial libraries. Nucleic Acids Symposium Series. 269-70. PMID 12903372 DOI: 10.1093/nass/44.1.269  0.669
2003 Cheng AC, Chen WW, Fuhrmann CN, Frankel AD. Recognition of nucleic acid bases and base-pairs by hydrogen bonding to amino acid side-chains. Journal of Molecular Biology. 327: 781-96. PMID 12654263 DOI: 10.1016/S0022-2836(03)00091-3  0.587
2003 Walberer BJ, Cheng AC, Frankel AD. Structural diversity and isomorphism of hydrogen-bonded base interactions in nucleic acids. Journal of Molecular Biology. 327: 767-80. PMID 12654262 DOI: 10.1016/S0022-2836(03)00090-1  0.726
2003 Peled-Zehavi H, Horiya S, Das C, Harada K, Frankel AD. Selection of RRE RNA binding peptides using a kanamycin antitermination assay. Rna (New York, N.Y.). 9: 252-61. PMID 12554868 DOI: 10.1261/Rna.2152303  0.829
2003 Xie B, Wainberg MA, Frankel AD. Replication of human immunodeficiency viruses engineered with heterologous Tat-transactivation response element interactions. Journal of Virology. 77: 1984-91. PMID 12525632 DOI: 10.1128/Jvi.77.3.1984-1991.2003  0.559
2002 Smith CA, Calabro V, Frankel AD. An RNA-binding chameleon. Molecular Cell. 6: 1067-76. PMID 11106746 DOI: 10.1016/S1097-2765(00)00105-2  0.552
2001 Cheng AC, Calabro V, Frankel AD. Design of RNA-binding proteins and ligands Current Opinion in Structural Biology. 11: 478-484. PMID 11495742 DOI: 10.1016/S0959-440X(00)00236-0  0.687
2001 Peled-Zehavi H, Berglund JA, Rosbash M, Frankel AD. Recognition of RNA branch point sequences by the KH domain of splicing factor 1 (mammalian branch point binding protein) in a splicing factor complex. Molecular and Cellular Biology. 21: 5232-41. PMID 11438677 DOI: 10.1128/Mcb.21.15.5232-5241.2001  0.517
2001 Reyes CM, Nifosì R, Frankel AD, Kollman PA. Molecular dynamics and binding specificity analysis of the bovine immunodeficiency virus BIV Tat-TAR complex. Biophysical Journal. 80: 2833-42. PMID 11371457 DOI: 10.1016/S0006-3495(01)76250-9  0.502
2001 Zhang Q, Harada K, Cho HS, Frankel AD, Wemmer DE. Structural characterization of the complex of the Rev response element RNA with a selected peptide. Chemistry & Biology. 8: 511-20. PMID 11358697 DOI: 10.1016/S1074-5521(01)00027-8  0.674
2001 Campisi DM, Calabro V, Frankel AD. Structure-based design of a dimeric RNA-peptide complex. The Embo Journal. 20: 178-86. PMID 11226168 DOI: 10.1093/Emboj/20.1.178  0.502
2000 Smith CA, Chen L, Frankel AD. Using peptides as models of RNA-protein interactions. Methods in Enzymology. 318: 423-38. PMID 10890003 DOI: 10.1016/S0076-6879(00)18067-X  0.464
2000 Landt SG, Tan R, Frankel AD. Screening RNA-binding libraries using Tat-fusion system in mammalian cells. Methods in Enzymology. 318: 350-63. PMID 10889998 DOI: 10.1016/S0076-6879(00)18062-0  0.812
2000 Peled-Zehavi H, Smith CA, Harada K, Frankel AD. Screening RNA-binding libraries by transcriptional antitermination in bacteria. Methods in Enzymology. 318: 297-308. PMID 10889995 DOI: 10.1016/S0076-6879(00)18059-0  0.666
2000 Frankel AD. Fitting peptides into the RNA world. Current Opinion in Structural Biology. 10: 332-40. PMID 10851193 DOI: 10.1016/S0959-440X(00)00092-0  0.472
2000 Harada K, Martin SS, Frankel AD. In vivo selection of RNA-binding peptides from combinatorial libraries. Nucleic Acids Symposium Series. 213-4. PMID 10780455 DOI: 10.1093/nass/42.1.213  0.603
2000 Robertson SA, Harada K, Frankel AD, Wemmer DE. Structure determination and binding kinetics of a DNA aptamer-argininamide complex. Biochemistry. 39: 946-54. PMID 10653638 DOI: 10.1021/Bi9915061  0.601
1999 Frankel AD. If the loop fits... Nature Structural Biology. 6: 1081-3. PMID 10581539 DOI: 10.1038/70002  0.514
1999 Harada K, Frankel AD. Screening RNA-binding libraries using a bacterial transcription antitermination assay. Methods in Molecular Biology (Clifton, N.J.). 118: 177-87. PMID 10549523 DOI: 10.1385/1-59259-676-2:177  0.664
1999 McColl DJ, Honchell CD, Frankel AD. Structure-based design of an RNA-binding zinc finger. Proceedings of the National Academy of Sciences of the United States of America. 96: 9521-6. PMID 10449725 DOI: 10.1073/Pnas.96.17.9521  0.503
1998 Frankel AD, Young JA. HIV-1: fifteen proteins and an RNA. Annual Review of Biochemistry. 67: 1-25. PMID 9759480 DOI: 10.1146/Annurev.Biochem.67.1.1  0.495
1998 Smith CA, Crotty S, Harada Y, Frankel AD. Altering the context of an RNA bulge switches the binding specificities of two viral Tat proteins Biochemistry. 37: 10808-10814. PMID 9692971 DOI: 10.1021/Bi980382+  0.559
1998 Tan R, Frankel AD. A novel glutamine-RNA interaction identified by screening libraries in mammalian cells Proceedings of the National Academy of Sciences of the United States of America. 95: 4247-4252. PMID 9539722 DOI: 10.1073/Pnas.95.8.4247  0.528
1998 Frankel AD, Smith CA. Induced folding in RNA-protein recognition: more than a simple molecular handshake. Cell. 92: 149-51. PMID 9458038 DOI: 10.1016/S0092-8674(00)80908-3  0.505
1997 Harada K, Martin SS, Tan R, Frankel AD. Molding a peptide into an RNA site by in vivo peptide evolution. Proceedings of the National Academy of Sciences of the United States of America. 94: 11887-92. PMID 9342332 DOI: 10.1073/Pnas.94.22.11887  0.705
1997 Tao J, Chen L, Frankel AD. Dissection of the proposed base triple in human immunodeficiency virus TAR RNA indicates the importance of the Hoogsteen interaction. Biochemistry. 36: 3491-5. PMID 9131998 DOI: 10.1021/Bi962259T  0.51
1997 Tan R, Brodsky A, Williamson JR, Frankel AD. RNA Recognition by HIV-1 Tat and Rev Seminars in Virology. 8: 186-193. DOI: 10.1006/Smvy.1997.0121  0.575
1996 Battiste JL, Mao H, Rao NS, Tan R, Muhandiram DR, Kay LE, Frankel AD, Williamson JR. Alpha helix-RNA major groove recognition in an HIV-1 rev peptide-RRE RNA complex. Science (New York, N.Y.). 273: 1547-51. PMID 8703216 DOI: 10.1126/Science.273.5281.1547  0.493
1996 Tao J, Frankel AD. Arginine-binding RNAs resembling TAR identified by in vitro selection. Biochemistry. 35: 2229-38. PMID 8652564 DOI: 10.1021/Bi951844B  0.51
1996 Harada K, Martin SS, Frankel AD. Selection of RNA-binding peptides in vivo. Nature. 380: 175-9. PMID 8600395 DOI: 10.1038/380175A0  0.71
1996 Battiste JL, Tan R, Frankel AD, Williamson JR. Assignment and modeling of the Rev Response Element RNA bound to a Rev peptide using 13C-heteronuclear NMR. Journal of Biomolecular Nmr. 6: 375-89. PMID 8563466 DOI: 10.1007/Bf00197637  0.51
1996 Harada K, Martin S, Frankel AD. Selection of RNA-binding peptides from combinatorial libraries Origins of Life and Evolution of the Biosphere. 26: 258-258. DOI: 10.1007/Bf02459744  0.671
1995 Tan R, Frankel AD. Structural variety of arginine-rich RNA-binding peptides Proceedings of the National Academy of Sciences of the United States of America. 92: 5282-5286. PMID 7777498 DOI: 10.1073/Pnas.92.12.5282  0.513
1995 Chen L, Frankel AD. A peptide interaction in the major groove of RNA resembles protein interactions in the minor groove of DNA. Proceedings of the National Academy of Sciences of the United States of America. 92: 5077-81. PMID 7761451 DOI: 10.1073/Pnas.92.11.5077  0.526
1995 Chen LL, Frankel AD, Harder JL, Fawell S, Barsoum J, Pepinsky B. Increased cellular uptake of the human immunodeficiency virus-1 Tat protein after modification with biotin. Analytical Biochemistry. 227: 168-75. PMID 7668378 DOI: 10.1006/Abio.1995.1267  0.351
1995 Puglisi JD, Chen L, Blanchard S, Frankel AD. Solution structure of a bovine immunodeficiency virus Tat-TAR peptide-RNA complex Science. 270: 1200-1203. PMID 7502045 DOI: 10.1126/Science.270.5239.1200  0.52
1995 Harada K, Frankel AD. Identification of two novel arginine binding DNAs. The Embo Journal. 14: 5798-5811. DOI: 10.1002/J.1460-2075.1995.Tb00268.X  0.692
1994 Battiste JL, Tan R, Frankel AD, Williamson JR. Binding of an HIV Rev peptide to Rev responsive element RNA induces formation of purine-purine base pairs. Biochemistry. 33: 2741-7. PMID 8130185 DOI: 10.1021/Bi00176A001  0.558
1994 Chen L, Frankel AD. An RNA-binding peptide from bovine immunodeficiency virus Tat protein recognizes an unusual RNA structure. Biochemistry. 33: 2708-15. PMID 8117736 DOI: 10.1021/Bi00175A046  0.57
1994 Tan R, Frankel AD. Costabilization of peptide and RNA structure in an HIV Rev peptide-RRE complex Biochemistry. 33: 14579-14585. PMID 7981219 DOI: 10.1021/Bi00252A025  0.513
1993 Tao J, Frankel AD. Electrostatic interactions modulate the RNA-binding and transactivation specificities of the human immunodeficiency virus and simian immunodeficiency virus Tat proteins. Proceedings of the National Academy of Sciences of the United States of America. 90: 1571-5. PMID 8434019 DOI: 10.1073/Pnas.90.4.1571  0.531
1993 Tan R, Chen L, Buettner JA, Hudson D, Frankel AD. RNA recognition by an isolated alpha helix. Cell. 73: 1031-40. PMID 7684657 DOI: 10.1016/0092-8674(93)90280-4  0.493
1993 Puglisi JD, Chen L, Frankel AD, Williamson JR. Role of RNA structure in arginine recognition of TAR RNA. Proceedings of the National Academy of Sciences of the United States of America. 90: 3680-4. PMID 7682716 DOI: 10.1073/Pnas.90.8.3680  0.5
1993 Frankel AD. Peptide models of the Tat-TAR protein-RNA interaction. Protein Science : a Publication of the Protein Society. 1: 1539-42. PMID 1304886 DOI: 10.1002/Pro.5560011202  0.468
1992 Frankel AD. Activation of HIV transcription by Tat. Current Opinion in Genetics & Development. 2: 293-8. PMID 1638124 DOI: 10.1016/S0959-437X(05)80287-4  0.402
1992 Puglisi JD, Tan R, Calnan BJ, Frankel AD, Williamson JR. Conformation of the TAR RNA-arginine complex by NMR spectroscopy. Science (New York, N.Y.). 257: 76-80. PMID 1621097 DOI: 10.1126/Science.1621097  0.536
1992 Tao J, Frankel AD. Specific binding of arginine to TAR RNA. Proceedings of the National Academy of Sciences of the United States of America. 89: 2723-6. PMID 1557378 DOI: 10.1073/Pnas.89.7.2723  0.518
1992 Kjems J, Calnan BJ, Frankel AD, Sharp PA. Specific binding of a basic peptide from HIV-1 Rev. The Embo Journal. 11: 1119-29. PMID 1547776 DOI: 10.1002/J.1460-2075.1992.Tb05152.X  0.583
1992 Tan R, Frankel AD. Circular dichroism studies suggest that TAR RNA changes conformation upon specific binding of arginine or guanidine Biochemistry. 31: 10288-10294. PMID 1384695 DOI: 10.1021/Bi00157A016  0.443
1992 Frankel AD. Activation of HIV transcription by Tat Current Biology. 2: 266. DOI: 10.1016/0960-9822(92)90385-N  0.372
1992 Kjems J, Calnan B, Frankel A, Sharp P. Specific binding of a basic peptide from HIV-1 Rev. The Embo Journal. 11: 1119-1129. DOI: 10.1002/j.1460-2075.1992.tb05152.x  0.302
1991 Feinberg MB, Baltimore D, Frankel AD. The role of Tat in the human immunodeficiency virus life cycle indicates a primary effect on transcriptional elongation. Proceedings of the National Academy of Sciences of the United States of America. 88: 4045-9. PMID 2023953 DOI: 10.1073/Pnas.88.9.4045  0.339
1991 Kjems J, Frankel AD, Sharp PA. Specific regulation of mRNA splicing in vitro by a peptide from HIV-1 Rev. Cell. 67: 169-78. PMID 1913815 DOI: 10.1016/0092-8674(91)90580-R  0.51
1991 Calnan BJ, Biancalana S, Hudson D, Frankel AD. Analysis of arginine-rich peptides from the HIV Tat protein reveals unusual features of RNA-protein recognition. Genes & Development. 5: 201-10. PMID 1899841 DOI: 10.1101/Gad.5.2.201  0.577
1991 Frankel AD, Mattaj IW, Rio DC. RNA-protein interactions. Cell. 67: 1041-6. PMID 1722140 DOI: 10.1016/0092-8674(91)90282-4  0.518
1991 Calnan BJ, Tidor B, Biancalana S, Hudson D, Frankel AD. Arginine-mediated RNA recognition: the arginine fork. Science (New York, N.Y.). 252: 1167-71. PMID 1709522 DOI: 10.1126/Science.252.5009.1167  0.535
1991 Mann D, Frankel A. Endocytosis and targeting of exogenous HIV-1 Tat protein. The Embo Journal. 10: 1733-1739. DOI: 10.1002/J.1460-2075.1991.Tb07697.X  0.419
1990 Viscidi RP, Mayur K, Lederman HM, Frankel AD. Inhibition of antigen-induced lymphocyte proliferation by Tat protein from HIV-1. Science (New York, N.Y.). 246: 1606-8. PMID 2556795 DOI: 10.1126/Science.2556795  0.374
1990 Marciniak RA, Calnan BJ, Frankel AD, Sharp PA. HIV-1 Tat protein trans-activates transcription in vitro. Cell. 63: 791-802. PMID 2225077 DOI: 10.1016/0092-8674(90)90145-5  0.521
1990 Daly TJ, Rusche JR, Maione TE, Frankel AD. Circular dichroism studies of the HIV-1 Rev protein and its specific RNA binding site Biochemistry. 29: 9791-9795. PMID 2125482 DOI: 10.1021/Bi00494A005  0.447
1989 Frankel AD, Biancalana S, Hudson D. Activity of synthetic peptides from the Tat protein of human immunodeficiency virus type 1. Proceedings of the National Academy of Sciences of the United States of America. 86: 7397-401. PMID 2552444 DOI: 10.1073/Pnas.86.19.7397  0.382
1988 Frankel AD, Pabo CO. Fingering too many proteins. Cell. 53: 675. PMID 3370671 DOI: 10.1016/0092-8674(88)90083-9  0.641
1988 Stearman RS, Frankel AD, Freire E, Liu BS, Pabo CO. Combining thermostable mutations increases the stability of lambda repressor. Biochemistry. 27: 7571-4. PMID 3061460 DOI: 10.1021/Bi00419A059  0.601
1988 Frankel AD, Pabo CO. Cellular uptake of the tat protein from human immunodeficiency virus. Cell. 55: 1189-93. PMID 2849510 DOI: 10.1016/0092-8674(88)90263-2  0.674
1988 Frankel AD, Chen L, Cotter RJ, Pabo CO. Dimerization of the tat protein from human immunodeficiency virus: a cysteine-rich peptide mimics the normal metal-linked dimer interface. Proceedings of the National Academy of Sciences of the United States of America. 85: 6297-300. PMID 2842763 DOI: 10.1073/Pnas.85.17.6297  0.655
1988 Frankel AD, Bredt DS, Pabo CO. Tat protein from human immunodeficiency virus forms a metal-linked dimer. Science (New York, N.Y.). 240: 70-3. PMID 2832944 DOI: 10.1126/Science.2832944  0.654
1987 Frankel AD, Berg JM, Pabo CO. Metal-dependent folding of a single zinc finger from transcription factor IIIA. Proceedings of the National Academy of Sciences of the United States of America. 84: 4841-5. PMID 3474629 DOI: 10.1073/Pnas.84.14.4841  0.64
1985 Frankel AD, Ackers GK, Smith HO. Measurement of DNA-protein equilibria using gel chromatography: Application to the HinfI restriction endonuclease Biochemistry. 24: 3049-3054. PMID 2990540 DOI: 10.1021/Bi00333A037  0.707
1983 Pabo CO, Jordan SR, Frankel AD. Systematic analysis of possible hydrogen bonds between amino acid side chains and B-form DNA. Journal of Biomolecular Structure & Dynamics. 1: 1039-49. PMID 6400903 DOI: 10.1080/07391102.1983.10507501  0.602
1981 Frankel AD, Smith HO. Restriction and modification enzymes detect no allosteric changes in DNA with bound lac repressor or RNA polymerase. Journal of Molecular Biology. 146: 611-9. PMID 6268796 DOI: 10.1016/0022-2836(81)90049-8  0.616
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