Sergio Grinstein - Publications

Affiliations: 
University of Toronto, Toronto, ON, Canada 
Area:
Cell Biology, Biochemistry

412 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Zhu H, Sydor AM, Boddy KC, Coyaud E, Laurent EMN, Au A, Tan JMJ, Yan BR, Moffat J, Muise AM, Yip CM, Grinstein S, Raught B, Brumell JH. Salmonella exploits membrane reservoirs for invasion of host cells. Nature Communications. 15: 3120. PMID 38600106 DOI: 10.1038/s41467-024-47183-x  0.737
2024 Le T, Ferling I, Qiu L, Nabaile C, Assunção L, Roskelley CD, Grinstein S, Freeman SA. Redistribution of the glycocalyx exposes phagocytic determinants on apoptotic cells. Developmental Cell. PMID 38359833 DOI: 10.1016/j.devcel.2024.01.020  0.635
2023 Barreda D, Grinstein S, Freeman SA. Target lysis by cholesterol extraction is a rate limiting step in the resolution of phagolysosomes. European Journal of Cell Biology. 103: 151382. PMID 38171214 DOI: 10.1016/j.ejcb.2023.151382  0.65
2023 Case NT, Westman J, Hallett MT, Plumb J, Farheen A, Maxson ME, MacAlpine J, Liston SD, Hube B, Robbins N, Whitesell L, Grinstein S, Cowen LE. Respiration supports intraphagosomal filamentation and escape of from macrophages. Mbio. e0274523. PMID 38038475 DOI: 10.1128/mbio.02745-23  0.732
2023 Turner M, Plumb J, Merrill AR, Grinstein S, Westman J. Lysosomal swelling and lysis mediate delivery of C3 toxins to their cytoplasmic targets. Molecular Microbiology. PMID 37038088 DOI: 10.1111/mmi.15063  0.315
2023 Wu JZ, Zeziulia M, Kwon W, Jentsch TJ, Grinstein S, Freeman SA. ClC-7 drives intraphagosomal chloride accumulation to support hydrolase activity and phagosome resolution. The Journal of Cell Biology. 222. PMID 37010469 DOI: 10.1083/jcb.202208155  0.655
2023 Hirata Y, Cai R, Volchuk A, Steinberg BE, Saito Y, Matsuzawa A, Grinstein S, Freeman SA. Lipid peroxidation increases membrane tension, Piezo1 gating, and cation permeability to execute ferroptosis. Current Biology : Cb. PMID 36898371 DOI: 10.1016/j.cub.2023.02.060  0.805
2023 Shiraishi A, Uygun V, Sharfe N, Beldar S, Sun MGF, Dadi H, Vong L, Maxson M, Karaca NE, Mevlitoğlu S, Grinstein S, Artan R, Merico D, Roifman CM. Novel immunodeficiency caused by homozygous mutation in SLC19A1 encoding the reduced folate carrier. Blood. PMID 36745868 DOI: 10.1182/blood.2022017968  0.681
2022 Montaño-Rendón F, Walpole GFW, Krause M, Hammond GRV, Grinstein S, Fairn GD. PtdIns(3,4)P2, Lamellipodin, and VASP coordinate actin dynamics during phagocytosis in macrophages. The Journal of Cell Biology. 221. PMID 36165850 DOI: 10.1083/jcb.202207042  0.645
2022 Freeman SA, Grinstein S, Orlowski J. Determinants, Maintenance and Function of Organellar pH. Physiological Reviews. PMID 35981302 DOI: 10.1152/physrev.00009.2022  0.652
2022 Mylvaganam S, Plumb J, Yusuf B, Li R, Lu CY, Robinson LA, Freeman SA, Grinstein S. The spectrin cytoskeleton integrates endothelial mechanoresponses. Nature Cell Biology. PMID 35817960 DOI: 10.1038/s41556-022-00953-5  0.626
2022 Walpole GFW, Pacheco J, Chauhan N, Clark J, Anderson KE, Abbas YM, Brabant-Kirwan D, Montaño-Rendón F, Liu Z, Zhu H, Brumell JH, Deiters A, Stephens LR, Hawkins PT, Hammond GRV, ... Grinstein S, et al. Kinase-independent synthesis of 3-phosphorylated phosphoinositides by a phosphotransferase. Nature Cell Biology. PMID 35484249 DOI: 10.1038/s41556-022-00895-y  0.729
2022 Maxson ME, Abbas YM, Wu JZ, Plumb JD, Grinstein S, Rubinstein JL. Detection and quantification of the vacuolar H+ATPase using the Legionella effector protein SidK. The Journal of Cell Biology. 221. PMID 35024770 DOI: 10.1083/jcb.202107174  0.76
2022 Westman J, Plumb J, Licht A, Yang M, Allert S, Naglik JR, Hube B, Grinstein S, Maxson ME. Calcium-dependent ESCRT recruitment and lysosome exocytosis maintain epithelial integrity during Candida albicans invasion. Cell Reports. 38: 110187. PMID 34986345 DOI: 10.1016/j.celrep.2021.110187  0.748
2021 Tan JMJ, Garner ME, Regeimbal JM, Greene CJ, Márquez JDR, Ammendolia DA, McCluggage ARR, Li T, Wu KJ, Cemma M, Ostrowski PP, Raught B, Diamond MS, Grinstein S, Yates RM, et al. Listeria exploits IFITM3 to suppress antibacterial activity in phagocytes. Nature Communications. 12: 4999. PMID 34404769 DOI: 10.1038/s41467-021-24982-0  0.542
2021 Boddy KC, Zhu H, D'Costa VM, Xu C, Beyrakhova K, Cygler M, Grinstein S, Coyaud E, Laurent EMN, St-Germain J, Raught B, Brumell JH. Salmonella effector SopD promotes plasma membrane scission by inhibiting Rab10. Nature Communications. 12: 4707. PMID 34349110 DOI: 10.1038/s41467-021-24983-z  0.6
2021 Freeman S, Grinstein S. Promoters and Antagonists of Phagocytosis: A Plastic and Tunable Response. Annual Review of Cell and Developmental Biology. PMID 34152790 DOI: 10.1146/annurev-cellbio-120219-055903  0.624
2021 Mylvaganam S, Freeman SA, Grinstein S. The cytoskeleton in phagocytosis and macropinocytosis. Current Biology : Cb. 31: R619-R632. PMID 34033794 DOI: 10.1016/j.cub.2021.01.036  0.678
2021 Maxson ME, Sarantis H, Volchuk A, Brumell JH, Grinstein S. Rab5 regulates macropinocytosis by recruiting the inositol 5-phosphatases OCRL/Inpp5b that hydrolyze PtdIns(4,5)P. Journal of Cell Science. PMID 33722976 DOI: 10.1242/jcs.252411  0.802
2021 Chadwick SR, Grinstein S, Freeman SA. From the inside out: Ion fluxes at the centre of endocytic traffic. Current Opinion in Cell Biology. 71: 77-86. PMID 33706237 DOI: 10.1016/j.ceb.2021.02.006  0.642
2020 Imbert PRC, Saric A, Pedram K, Bertozzi CR, Grinstein S, Freeman SA. An Acquired and Endogenous Glycocalyx Forms a Bidirectional "Don't Eat" and "Don't Eat Me" Barrier to Phagocytosis. Current Biology : Cb. PMID 33096038 DOI: 10.1016/j.cub.2020.09.082  0.62
2020 Westman J, Freeman SA, Grinstein S. Unconventional role of lysosomes in phagocytosis. Cell Calcium. 91: 102269. PMID 32818767 DOI: 10.1016/J.Ceca.2020.102269  0.656
2020 Bhosle VK, Mukherjee T, Huang YW, Patel S, Pang BWF, Liu GY, Glogauer M, Wu JY, Philpott DJ, Grinstein S, Robinson LA. SLIT2/ROBO1-signaling inhibits macropinocytosis by opposing cortical cytoskeletal remodeling. Nature Communications. 11: 4112. PMID 32807784 DOI: 10.1038/S41467-020-17651-1  0.346
2020 Mylvaganam S, Riedl M, Vega A, Collins RF, Jaqaman K, Grinstein S, Freeman SA. Stabilization of Endothelial Receptor Arrays by a Polarized Spectrin Cytoskeleton Facilitates Rolling and Adhesion of Leukocytes. Cell Reports. 31: 107798. PMID 32579925 DOI: 10.1016/J.Celrep.2020.107798  0.643
2020 Walpole GFW, Grinstein S. Endocytosis and the internalization of pathogenic organisms: focus on phosphoinositides. F1000research. 9. PMID 32494357 DOI: 10.12688/F1000Research.22393.1  0.393
2020 Walpole GFW, Plumb JD, Chung D, Tang B, Boulay B, Osborne DG, Piotrowski JT, Catz SD, Billadeau DD, Grinstein S, Jaumouillé V. Inactivation of Rho GTPases by Burkholderia cenocepacia Induces a WASH-Mediated Actin Polymerization that Delays Phagosome Maturation. Cell Reports. 31: 107721. PMID 32492429 DOI: 10.1016/J.Celrep.2020.107721  0.33
2020 Maxson ME, Grinstein S. The Role of Membrane Surface Charge in Phagocytosis. Advances in Experimental Medicine and Biology. 1246: 43-54. PMID 32399824 DOI: 10.1007/978-3-030-40406-2_3  0.756
2020 Riedl Khursigara M, Schlam D, Noone DG, Bruno V, Ortiz Sandoval CG, Pluthero FG, Kahr WHA, Bowman ML, James P, Grinstein S, Licht C. Vascular endothelial cells evade complement-mediated membrane injury via Weibel-Palade body mobilization. Journal of Thrombosis and Haemostasis : Jth. PMID 32073731 DOI: 10.1111/Jth.14767  0.336
2020 Freeman SA, Grinstein S. Phagocytosis: Mechanosensing, Traction Forces, and a Molecular Clutch. Current Biology : Cb. 30: R24-R26. PMID 31910372 DOI: 10.1016/J.Cub.2019.11.047  0.66
2019 Westman J, Grinstein S, Marques PE. Phagocytosis of Necrotic Debris at Sites of Injury and Inflammation. Frontiers in Immunology. 10: 3030. PMID 31998312 DOI: 10.3389/Fimmu.2019.03030  0.365
2019 Freeman SA, Uderhardt S, Saric A, Collins RF, Buckley CM, Mylvaganam S, Boroumand P, Plumb J, Germain RN, Ren D, Grinstein S. Lipid-gated monovalent ion fluxes regulate endocytic traffic and support immune surveillance. Science (New York, N.Y.). PMID 31806695 DOI: 10.1126/Science.Aaw9544  0.664
2019 Levin-Konigsberg R, Grinstein S. Phagosome-Endoplasmic Reticulum contacts: kissing and not running. Traffic (Copenhagen, Denmark). PMID 31650670 DOI: 10.1111/Tra.12708  0.321
2019 D'Costa VM, Coyaud E, Boddy KC, Laurent EMN, St-Germain J, Li T, Grinstein S, Raught B, Brumell JH. BioID screen of Salmonella type 3 secreted effectors reveals host factors involved in vacuole positioning and stability during infection. Nature Microbiology. PMID 31611645 DOI: 10.1038/S41564-019-0580-9  0.598
2019 Levin-Konigsberg R, Montaño-Rendón F, Keren-Kaplan T, Li R, Ego B, Mylvaganam S, DiCiccio JE, Trimble WS, Bassik MC, Bonifacino JS, Fairn GD, Grinstein S. Phagolysosome resolution requires contacts with the endoplasmic reticulum and phosphatidylinositol-4-phosphate signalling. Nature Cell Biology. PMID 31570833 DOI: 10.1038/S41556-019-0394-2  0.655
2019 Heybrock S, Kanerva K, Meng Y, Ing C, Liang A, Xiong ZJ, Weng X, Ah Kim Y, Collins R, Trimble W, Pomès R, Privé GG, Annaert W, Schwake M, Heeren J, ... ... Grinstein S, et al. Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export. Nature Communications. 10: 3521. PMID 31387993 DOI: 10.1038/S41467-019-11425-0  0.703
2019 Ostrowski PP, Freeman SA, Fairn G, Grinstein S. Dynamic Podosome-Like Structures in Nascent Phagosomes Are Coordinated by Phosphoinositides. Developmental Cell. PMID 31231039 DOI: 10.1016/J.Devcel.2019.05.028  0.765
2019 Marques PE, Nyegaard S, Collins RF, Troise F, Freeman SA, Trimble WS, Grinstein S. Multimerization and Retention of the Scavenger Receptor SR-B1 in the Plasma Membrane. Developmental Cell. PMID 31231038 DOI: 10.1016/J.Devcel.2019.05.026  0.668
2019 Westman J, Grinstein S, Maxson ME. Revisiting the role of calcium in phagosome formation and maturation. Journal of Leukocyte Biology. PMID 31091355 DOI: 10.1002/Jlb.Mr1118-444R  0.746
2019 Doodnauth SA, Grinstein S, Maxson ME. Constitutive and stimulated macropinocytosis in macrophages: roles in immunity and in the pathogenesis of atherosclerosis. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 374: 20180147. PMID 30967001 DOI: 10.1098/Rstb.2018.0147  0.765
2018 Mylvaganam SM, Grinstein S, Freeman SA. Picket-fences in the plasma membrane: functions in immune cells and phagocytosis. Seminars in Immunopathology. PMID 30209546 DOI: 10.1007/S00281-018-0705-X  0.698
2018 Westman J, Moran G, Mogavero S, Hube B, Grinstein S. Candida albicans Hyphal Expansion Causes Phagosomal Membrane Damage and Luminal Alkalinization. Mbio. 9. PMID 30206168 DOI: 10.1128/Mbio.01226-18  0.37
2018 Freeman SA, Grinstein S. Resolution of macropinosomes, phagosomes, and autolysosomes: osmotically-driven shrinkage enables tubulation and vesiculation. Traffic (Copenhagen, Denmark). PMID 30159984 DOI: 10.1111/Tra.12614  0.689
2018 O'Meara TR, Duah K, Guo CX, Maxson ME, Gaudet RG, Koselny K, Wellington M, Powers ME, MacAlpine J, O'Meara MJ, Veri AO, Grinstein S, Noble SM, Krysan D, Gray-Owen SD, et al. High-Throughput Screening Identifies Genes Required for Induction of Macrophage Pyroptosis. Mbio. 9. PMID 30131363 DOI: 10.1128/Mbio.01581-18  0.754
2018 Schlam D, Grinstein S, Freeman SA. Screening for Rho GTPase Modulators in Actin-Dependent Processes Exemplified by Phagocytosis. Methods in Molecular Biology (Clifton, N.J.). 1821: 107-127. PMID 30062408 DOI: 10.1007/978-1-4939-8612-5_8  0.672
2018 Truong D, Boddy KC, Canadien V, Brabant D, Fairn GD, D'Costa VM, Coyaud E, Raught B, Perez-Sala D, Park WS, Do Heo W, Grinstein S, Brumell JH. Salmonella exploits host Rho GTPase signalling pathways through the phosphatase activity of SopB. Cellular Microbiology. e12938. PMID 30010242 DOI: 10.1111/Cmi.12938  0.75
2018 Montaño F, Grinstein S, Levin R. Quantitative Phagocytosis Assays in Primary and Cultured Macrophages. Methods in Molecular Biology (Clifton, N.J.). 1784: 151-163. PMID 29761397 DOI: 10.1007/978-1-4939-7837-3_15  0.301
2018 Walpole GFW, Grinstein S, Westman J. The role of lipids in host-pathogen interactions. Iubmb Life. 70: 384-392. PMID 29573124 DOI: 10.1002/Iub.1737  0.36
2018 Maxson ME, Naj X, O'Meara TR, Plumb JD, Cowen LE, Grinstein S. Integrin-based diffusion barrier separates membrane domains enabling formation of microbiostatic frustrated phagosomes. Elife. 7. PMID 29553370 DOI: 10.7554/Elife.34798  0.776
2018 Vega AR, Freeman SA, Grinstein S, Jaqaman K. Multistep Track Segmentation and Motion Classification for Transient Mobility Analysis. Biophysical Journal. 114: 1018-1025. PMID 29539390 DOI: 10.1016/J.Bpj.2018.01.012  0.575
2018 Rabani R, Volchuk A, Jerkic M, Ormesher L, Garces-Ramirez L, Canton J, Masterson C, Gagnon S, Tatham KC, Marshall J, Grinstein S, Laffey JG, Szaszi K, Curley GF. Mesenchymal stem cells enhance NOX2 dependent ROS production and bacterial killing in macrophages during sepsis. The European Respiratory Journal. PMID 29519920 DOI: 10.1183/13993003.02021-2017  0.301
2018 Niedergang F, Grinstein S. How to build a phagosome: new concepts for an old process. Current Opinion in Cell Biology. 50: 57-63. PMID 29471269 DOI: 10.1016/J.Ceb.2018.01.009  0.338
2018 Freeman SA, Vega A, Riedl M, Collins RF, Ostrowski PP, Woods EC, Bertozzi CR, Tammi MI, Lidke DS, Johnson P, Mayor S, Jaqaman K, Grinstein S. Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement. Cell. 172: 305-317.e10. PMID 29328918 DOI: 10.1016/J.Cell.2017.12.023  0.616
2018 Maxson ME, Naj X, O'Meara TR, Plumb JD, Cowen LE, Grinstein S. Author response: Integrin-based diffusion barrier separates membrane domains enabling the formation of microbiostatic frustrated phagosomes Elife. DOI: 10.7554/Elife.34798.042  0.32
2018 Grinstein S, Freeman SA. Receptor Mobility is Regulated by the Cytoskeleton Connected to an Exoskeleton via Transmembrane Pickets: Role in Phagocytosis Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.081  0.645
2017 Sharfe N, Karanxha A, Dadi H, Merico D, Chitayat D, Herbrick JA, Freeman S, Grinstein S, Roifman CM. Dual loss of p110δ PI3-kinase and SKAP (KNSTRN) expression leads to combined immunodeficiency and multisystem syndromic features. The Journal of Allergy and Clinical Immunology. PMID 29180244 DOI: 10.1016/J.Jaci.2017.10.033  0.609
2017 Hirama T, Lu SM, Kay JG, Maekawa M, Kozlov MM, Grinstein S, Fairn GD. Membrane curvature induced by proximity of anionic phospholipids can initiate endocytosis. Nature Communications. 8: 1393. PMID 29123120 DOI: 10.1038/S41467-017-01554-9  0.669
2017 Redka DS, Gütschow M, Grinstein S, Canton J. Differential ability of pro-inflammatory and anti-inflammatory macrophages to perform macropinocytosis. Molecular Biology of the Cell. PMID 29093026 DOI: 10.1091/Mbc.E17-06-0419  0.301
2017 Stefan CJ, Trimble WS, Grinstein S, Drin G, Reinisch K, De Camilli P, Cohen S, Valm AM, Lippincott-Schwartz J, Levine TP, Iaea DB, Maxfield FR, Futter CE, Eden ER, Judith D, et al. Membrane dynamics and organelle biogenesis-lipid pipelines and vesicular carriers. Bmc Biology. 15: 102. PMID 29089042 DOI: 10.1186/S12915-017-0432-0  0.39
2017 Hirama T, Das R, Yang Y, Ferguson C, Won A, Yip CM, Kay JG, Grinstein S, Parton RG, Fairn GD. Phosphatidylserine dictates the assembly and dynamics of caveolae in the plasma membrane. The Journal of Biological Chemistry. PMID 28698382 DOI: 10.1074/Jbc.M117.791400  0.698
2017 Lim JJ, Grinstein S, Roth Z. Diversity and Versatility of Phagocytosis: Roles in Innate Immunity, Tissue Remodeling, and Homeostasis. Frontiers in Cellular and Infection Microbiology. 7: 191. PMID 28589095 DOI: 10.3389/Fcimb.2017.00191  0.336
2017 Marques PE, Grinstein S, Freeman SA. SnapShot:Macropinocytosis. Cell. 169: 766-766.e1. PMID 28475901 DOI: 10.1016/j.cell.2017.04.031  0.599
2017 Levin R, Hammond GR, Balla T, De Camilli P, Fairn GD, Grinstein S. Multiphasic dynamics of phosphatidylinositol 4-phosphate during phagocytosis. Molecular Biology of the Cell. 28: 128-140. PMID 28035045 DOI: 10.1091/Mbc.E16-06-0451  0.682
2017 Lu SM, Grinstein S, Fairn GD. Quantitative Live-Cell Fluorescence Microscopy During Phagocytosis. Methods in Molecular Biology (Clifton, N.J.). 1519: 79-91. PMID 27815874 DOI: 10.1007/978-1-4939-6581-6_6  0.635
2016 Saric A, Grinstein S, Freeman SA. Measurement of Autolysosomal pH by Dual-Wavelength Ratio Imaging. Methods in Enzymology. 588: 15-29. PMID 28237098 DOI: 10.1016/bs.mie.2016.09.073  0.634
2016 Freeman SA, Grinstein S. Phagocytosis: How Macrophages Tune Their Non-professional Counterparts. Current Biology : Cb. 26: R1279-R1282. PMID 27997839 DOI: 10.1016/J.Cub.2016.10.059  0.644
2016 Ostrowski PP, Fairn GD, Grinstein S, Johnson DE. Cresyl violet: a superior fluorescent lysosomal marker. Traffic (Copenhagen, Denmark). PMID 27621028 DOI: 10.1111/Tra.12447  0.66
2016 Howard JC, Florentinus-Mefailoski A, Bowden P, Trimble W, Grinstein S, Marshall JG. OxLDL receptor chromatography from live human U937 cells identifies SYK(L) that regulates phagocytosis of oxLDL. Analytical Biochemistry. PMID 27510553 DOI: 10.1016/J.Ab.2016.07.021  0.32
2016 Ostrowski PP, Grinstein S, Freeman SA. Diffusion Barriers, Mechanical Forces, and the Biophysics of Phagocytosis. Developmental Cell. 38: 135-46. PMID 27459066 DOI: 10.1016/J.Devcel.2016.06.023  0.69
2016 Jaumouillé V, Grinstein S. Molecular Mechanisms of Phagosome Formation. Microbiology Spectrum. 4. PMID 27337463 DOI: 10.1128/Microbiolspec.Mchd-0013-2015  0.39
2016 Cemma M, Grinstein S, Brumell JH. Autophagy Proteins are not Universally Required for Phagosome Maturation. Autophagy. 0. PMID 27310610 DOI: 10.1080/15548627.2016.1191724  0.586
2016 Canton J, Schlam D, Breuer C, Gütschow M, Glogauer M, Grinstein S. Calcium-sensing receptors signal constitutive macropinocytosis and facilitate the uptake of NOD2 ligands in macrophages. Nature Communications. 7: 11284. PMID 27050483 DOI: 10.1038/Ncomms11284  0.364
2016 Schlam D, Canton J, Carreño M, Kopinski H, Freeman SA, Grinstein S, Fairn GD. Gliotoxin Suppresses Macrophage Immune Function by Subverting Phosphatidylinositol 3,4,5-Trisphosphate Homeostasis. Mbio. 7. PMID 27048806 DOI: 10.1128/Mbio.02242-15  0.79
2016 Wong HS, Jaumouillé V, Freeman SA, Doodnauth SA, Schlam D, Canton J, Mukovozov IM, Saric A, Grinstein S, Robinson LA. Chemokine Signaling Enhances CD36 Responsiveness toward Oxidized Low-Density Lipoproteins and Accelerates Foam Cell Formation. Cell Reports. PMID 26997267 DOI: 10.1016/j.celrep.2016.02.071  0.628
2016 Johnson DE, Ostrowski P, Jaumouillé V, Grinstein S. The position of lysosomes within the cell determines their luminal pH. The Journal of Cell Biology. 212: 677-92. PMID 26975849 DOI: 10.1083/Jcb.201507112  0.405
2016 Vance DT, Dufresne J, Florentinus-Mefailoski A, Tucholska M, Trimble W, Grinstein S, Marshall JG. A phagocytosis assay for oxLDL versus IgG coated microbeads in human U937 macrophages. Analytical Biochemistry. PMID 26800863 DOI: 10.1016/J.Ab.2016.01.007  0.315
2016 Freeman SA, Goyette J, Furuya W, Woods EC, Bertozzi CR, Bergmeier W, Hinz B, van der Merwe PA, Das R, Grinstein S. Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis. Cell. 164: 128-140. PMID 26771488 DOI: 10.1016/J.Cell.2015.11.048  0.61
2015 Schlam D, Bagshaw RD, Freeman SA, Collins RF, Pawson T, Fairn GD, Grinstein S. Phosphoinositide 3-kinase enables phagocytosis of large particles by terminating actin assembly through Rac/Cdc42 GTPase-activating proteins. Nature Communications. 6: 8623. PMID 26465210 DOI: 10.1038/Ncomms9623  0.765
2015 D'Costa VM, Braun V, Landekic M, Shi R, Proteau A, McDonald L, Cygler M, Grinstein S, Brumell JH. Salmonella Disrupts Host Endocytic Trafficking by SopD2-Mediated Inhibition of Rab7. Cell Reports. 12: 1508-18. PMID 26299973 DOI: 10.1016/J.Celrep.2015.07.063  0.607
2015 Freeman SA, Jaumouillé V, Choi K, Hsu BE, Wong HS, Abraham L, Graves ML, Coombs D, Roskelley CD, Das R, Grinstein S, Gold MR. Erratum: Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor. Nature Communications. 6: 7015. PMID 25881569 DOI: 10.1038/ncomms8015  0.606
2015 Trimble WS, Grinstein S. Barriers to the free diffusion of proteins and lipids in the plasma membrane. The Journal of Cell Biology. 208: 259-71. PMID 25646084 DOI: 10.1083/Jcb.201410071  0.379
2015 Freeman SA, Jaumouillé V, Choi K, Hsu BE, Wong HS, Abraham L, Graves ML, Coombs D, Roskelley CD, Das R, Grinstein S, Gold MR. Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor. Nature Communications. 6: 6168. PMID 25644899 DOI: 10.1038/Ncomms7168  0.672
2014 Maxson ME, Grinstein S. The vacuolar-type H⁺-ATPase at a glance - more than a proton pump. Journal of Cell Science. 127: 4987-93. PMID 25453113 DOI: 10.1242/jcs.158550  0.76
2014 Freeman SA, Grinstein S. Phagocytosis: receptors, signal integration, and the cytoskeleton. Immunological Reviews. 262: 193-215. PMID 25319336 DOI: 10.1111/imr.12212  0.647
2014 Dodd DA, Worth RG, Rosen MK, Grinstein S, van Oers NS, Hansen EJ. The Haemophilus ducreyi LspA1 protein inhibits phagocytosis by using a new mechanism involving activation of C-terminal Src kinase. Mbio. 5: e01178-14. PMID 24902122 DOI: 10.1128/Mbio.01178-14  0.379
2014 Zhang F, Wang Z, Lu M, Yonekubo Y, Liang X, Zhang Y, Wu P, Zhou Y, Grinstein S, Hancock JF, Du G. Temporal production of the signaling lipid phosphatidic acid by phospholipase D2 determines the output of extracellular signal-regulated kinase signaling in cancer cells. Molecular and Cellular Biology. 34: 84-95. PMID 24164897 DOI: 10.1128/Mcb.00987-13  0.331
2013 Neculai D, Schwake M, Ravichandran M, Zunke F, Collins RF, Peters J, Neculai M, Plumb J, Loppnau P, Pizarro JC, Seitova A, Trimble WS, Saftig P, Grinstein S, Dhe-Paganon S. Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36. Nature. 504: 172-6. PMID 24162852 DOI: 10.1038/Nature12684  0.68
2013 Roppenser B, Kwon H, Canadien V, Xu R, Devreotes PN, Grinstein S, Brumell JH. Multiple host kinases contribute to Akt activation during Salmonella infection. Plos One. 8: e71015. PMID 23990921 DOI: 10.1371/Journal.Pone.0071015  0.597
2013 Mukherjee D, Sen A, Boettner DR, Fairn GD, Schlam D, Bonilla Valentin FJ, Michael McCaffery J, Hazbun T, Staiger CJ, Grinstein S, Lemmon SK, Claudio Aguilar R. Bem3, a Cdc42 GTPase-activating protein, traffics to an intracellular compartment and recruits the secretory Rab GTPase Sec4 to endomembranes. Journal of Cell Science. 126: 4560-71. PMID 23943876 DOI: 10.1242/Jcs.117663  0.703
2013 Canton J, Neculai D, Grinstein S. Scavenger receptors in homeostasis and immunity. Nature Reviews. Immunology. 13: 621-34. PMID 23928573 DOI: 10.1038/Nri3515  0.653
2013 Strijbis K, Tafesse FG, Fairn GD, Witte MD, Dougan SK, Watson N, Spooner E, Esteban A, Vyas VK, Fink GR, Grinstein S, Ploegh HL. Bruton's Tyrosine Kinase (BTK) and Vav1 contribute to Dectin1-dependent phagocytosis of Candida albicans in macrophages. Plos Pathogens. 9: e1003446. PMID 23825946 DOI: 10.1371/Journal.Ppat.1003446  0.672
2013 Schlam D, Bohdanowicz M, Chatgilialoglu A, Chatilialoglu A, Steinberg BE, Ueyama T, Du G, Grinstein S, Fairn GD. Diacylglycerol kinases terminate diacylglycerol signaling during the respiratory burst leading to heterogeneous phagosomal NADPH oxidase activation. The Journal of Biological Chemistry. 288: 23090-104. PMID 23814057 DOI: 10.1074/Jbc.M113.457606  0.664
2013 Kay JG, Grinstein S. Phosphatidylserine-mediated cellular signaling. Advances in Experimental Medicine and Biology. 991: 177-93. PMID 23775696 DOI: 10.1007/978-94-007-6331-9_10  0.386
2013 Bohdanowicz M, Schlam D, Hermansson M, Rizzuti D, Fairn GD, Ueyama T, Somerharju P, Du G, Grinstein S. Phosphatidic acid is required for the constitutive ruffling and macropinocytosis of phagocytes. Molecular Biology of the Cell. 24: 1700-12, S1-7. PMID 23576545 DOI: 10.1091/Mbc.E12-11-0789  0.687
2013 Hayashi H, Tamura A, Krishnan D, Tsukita S, Suzuki Y, Kocinsky HS, Aronson PS, Orlowski J, Grinstein S, Alexander RT. Ezrin is required for the functional regulation of the epithelial sodium proton exchanger, NHE3. Plos One. 8: e55623. PMID 23405179 DOI: 10.1371/Journal.Pone.0055623  0.423
2013 Bohdanowicz M, Grinstein S. Role of phospholipids in endocytosis, phagocytosis, and macropinocytosis. Physiological Reviews. 93: 69-106. PMID 23303906 DOI: 10.1152/Physrev.00002.2012  0.409
2012 Nordenfelt P, Grinstein S, Björck L, Tapper H. V-ATPase-mediated phagosomal acidification is impaired by Streptococcus pyogenes through Mga-regulated surface proteins. Microbes and Infection / Institut Pasteur. 14: 1319-29. PMID 22981599 DOI: 10.1016/J.Micinf.2012.08.005  0.382
2012 Fairn GD, Grinstein S. Cell biology. Precursor or charge supplier? Science (New York, N.Y.). 337: 653-4. PMID 22879491 DOI: 10.1126/science.1227096  0.576
2012 Coen K, Flannagan RS, Baron S, Carraro-Lacroix LR, Wang D, Vermeire W, Michiels C, Munck S, Baert V, Sugita S, Wuytack F, Hiesinger PR, Grinstein S, Annaert W. Lysosomal calcium homeostasis defects, not proton pump defects, cause endo-lysosomal dysfunction in PSEN-deficient cells. The Journal of Cell Biology. 198: 23-35. PMID 22753898 DOI: 10.1083/Jcb.201201076  0.352
2012 Fairn GD, Grinstein S. How nascent phagosomes mature to become phagolysosomes. Trends in Immunology. 33: 397-405. PMID 22560866 DOI: 10.1016/j.it.2012.03.003  0.671
2012 Lee BH, Hwang DM, Palaniyar N, Grinstein S, Philpott DJ, Hu J. Activation of P2X(7) receptor by ATP plays an important role in regulating inflammatory responses during acute viral infection. Plos One. 7: e35812. PMID 22558229 DOI: 10.1371/Journal.Pone.0035812  0.332
2012 Kay JG, Koivusalo M, Ma X, Wohland T, Grinstein S. Phosphatidylserine dynamics in cellular membranes. Molecular Biology of the Cell. 23: 2198-212. PMID 22496416 DOI: 10.1091/Mbc.E11-11-0936  0.365
2012 Sarantis H, Balkin DM, De Camilli P, Isberg RR, Brumell JH, Grinstein S. Yersinia entry into host cells requires Rab5-dependent dephosphorylation of PI(4,5)Pâ‚‚ and membrane scission. Cell Host & Microbe. 11: 117-28. PMID 22341461 DOI: 10.1016/J.Chom.2012.01.010  0.659
2012 Sarantis H, Grinstein S. Monitoring phospholipid dynamics during phagocytosis: application of genetically-encoded fluorescent probes. Methods in Cell Biology. 108: 429-44. PMID 22325613 DOI: 10.1016/B978-0-12-386487-1.00019-5  0.372
2012 Roppenser B, Grinstein S, Brumell JH. Modulation of host phosphoinositide metabolism during Salmonella invasion by the type III secreted effector SopB. Methods in Cell Biology. 108: 173-86. PMID 22325603 DOI: 10.1016/B978-0-12-386487-1.00009-2  0.622
2012 Bohdanowicz M, Balkin DM, De Camilli P, Grinstein S. Recruitment of OCRL and Inpp5B to phagosomes by Rab5 and APPL1 depletes phosphoinositides and attenuates Akt signaling. Molecular Biology of the Cell. 23: 176-87. PMID 22072788 DOI: 10.1091/Mbc.E11-06-0489  0.383
2012 Flannagan RS, Jaumouillé V, Huynh KK, Plumb JD, Downey GP, Valvano MA, Grinstein S. Burkholderia cenocepacia disrupts host cell actin cytoskeleton by inactivating Rac and Cdc42. Cellular Microbiology. 14: 239-54. PMID 22023324 DOI: 10.1111/J.1462-5822.2011.01715.X  0.348
2012 Flannagan RS, Jaumouillé V, Grinstein S. The cell biology of phagocytosis. Annual Review of Pathology. 7: 61-98. PMID 21910624 DOI: 10.1146/Annurev-Pathol-011811-132445  0.325
2011 Orlowski J, Grinstein S. Na+/H+ exchangers. Comprehensive Physiology. 1: 2083-100. PMID 23733698 DOI: 10.1002/Cphy.C110020  0.362
2011 Kay JG, Grinstein S. Sensing phosphatidylserine in cellular membranes. Sensors (Basel, Switzerland). 11: 1744-55. PMID 22319379 DOI: 10.3390/S110201744  0.408
2011 Lam GY, Fattouh R, Muise AM, Grinstein S, Higgins DE, Brumell JH. Listeriolysin O suppresses phospholipase C-mediated activation of the microbicidal NADPH oxidase to promote Listeria monocytogenes infection. Cell Host & Microbe. 10: 627-34. PMID 22177565 DOI: 10.1016/J.Chom.2011.11.005  0.796
2011 Fairn GD, Hermansson M, Somerharju P, Grinstein S. Phosphatidylserine is polarized and required for proper Cdc42 localization and for development of cell polarity. Nature Cell Biology. 13: 1424-30. PMID 21964439 DOI: 10.1038/Ncb2351  0.653
2011 Jaqaman K, Kuwata H, Touret N, Collins R, Trimble WS, Danuser G, Grinstein S. Cytoskeletal control of CD36 diffusion promotes its receptor and signaling function. Cell. 146: 593-606. PMID 21854984 DOI: 10.1016/J.Cell.2011.06.049  0.309
2011 Kaniuk NA, Canadien V, Bagshaw RD, Bakowski M, Braun V, Landekic M, Mitra S, Huang J, Heo WD, Meyer T, Pelletier L, Andrews-Polymenis H, McClelland M, Pawson T, Grinstein S, et al. Salmonella exploits Arl8B-directed kinesin activity to promote endosome tubulation and cell-to-cell transfer. Cellular Microbiology. 13: 1812-23. PMID 21824248 DOI: 10.1111/J.1462-5822.2011.01663.X  0.607
2011 Carraro-Lacroix LR, Jaumouillé V, Fairn GD, Grinstein S. A weak base-generating system suitable for selective manipulation of lysosomal pH. Traffic (Copenhagen, Denmark). 12: 1490-500. PMID 21819499 DOI: 10.1111/J.1600-0854.2011.01266.X  0.66
2011 Golebiewska U, Kay JG, Masters T, Grinstein S, Im W, Pastor RW, Scarlata S, McLaughlin S. Evidence for a fence that impedes the diffusion of phosphatidylinositol 4,5-bisphosphate out of the forming phagosomes of macrophages. Molecular Biology of the Cell. 22: 3498-507. PMID 21795401 DOI: 10.1091/Mbc.E11-02-0114  0.347
2011 Fairn GD, Schieber NL, Ariotti N, Murphy S, Kuerschner L, Webb RI, Grinstein S, Parton RG. High-resolution mapping reveals topologically distinct cellular pools of phosphatidylserine. The Journal of Cell Biology. 194: 257-75. PMID 21788369 DOI: 10.1083/Jcb.201012028  0.671
2011 Botelho RJ, Grinstein S. Phagocytosis. Current Biology : Cb. 21: R533-8. PMID 21783028 DOI: 10.1016/j.cub.2011.05.053  0.587
2011 Koivusalo M, Steinberg BE, Mason D, Grinstein S. In situ measurement of the electrical potential across the lysosomal membrane using FRET. Traffic (Copenhagen, Denmark). 12: 972-82. PMID 21554506 DOI: 10.1111/J.1600-0854.2011.01215.X  0.413
2011 Alexander RT, Jaumouillé V, Yeung T, Furuya W, Peltekova I, Boucher A, Zasloff M, Orlowski J, Grinstein S. Membrane surface charge dictates the structure and function of the epithelial Na+/H+ exchanger. The Embo Journal. 30: 679-91. PMID 21245831 DOI: 10.1038/Emboj.2010.356  0.409
2011 Jaumouillé V, Grinstein S. Receptor mobility, the cytoskeleton, and particle binding during phagocytosis. Current Opinion in Cell Biology. 23: 22-9. PMID 21074980 DOI: 10.1016/J.Ceb.2010.10.006  0.316
2011 Heit B, Yeung T, Grinstein S. Changes in mitochondrial surface charge mediate recruitment of signaling molecules during apoptosis. American Journal of Physiology. Cell Physiology. 300: C33-41. PMID 20926778 DOI: 10.1152/Ajpcell.00139.2010  0.306
2011 Jaqaman K, Kuwata H, Touret N, Collins R, Trimble WS, Danuser G, Grinstein S. Cytoskeletal Control of Receptor Diffusion in Membrane Promotes CD36 Function and Signaling Biophysical Journal. 100: 21a. DOI: 10.1016/J.Bpj.2010.12.323  0.34
2010 Flannagan RS, Harrison RE, Yip CM, Jaqaman K, Grinstein S. Dynamic macrophage "probing" is required for the efficient capture of phagocytic targets Journal of Cell Biology. 191: 1205-1218. PMID 21135140 DOI: 10.1083/Jcb.201007056  0.367
2010 Bohdanowicz M, Cosío G, Backer JM, Grinstein S. Class I and class III phosphoinositide 3-kinases are required for actin polymerization that propels phagosomes. The Journal of Cell Biology. 191: 999-1012. PMID 21115805 DOI: 10.1083/Jcb.201004005  0.376
2010 Lee BH, Kushwah R, Wu J, Ng P, Palaniyar N, Grinstein S, Philpott DJ, Hu J. Adenoviral vectors stimulate innate immune responses in macrophages through cross-talk with epithelial cells. Immunology Letters. 134: 93-102. PMID 20850478 DOI: 10.1016/J.Imlet.2010.09.003  0.319
2010 Huynh KK, Plumb JD, Downey GP, Valvano MA, Grinstein S. Inactivation of macrophage Rab7 by Burkholderia cenocepacia. Journal of Innate Immunity. 2: 522-33. PMID 20829607 DOI: 10.1159/000319864  0.355
2010 Steinberg BE, Huynh KK, Brodovitch A, Jabs S, Stauber T, Jentsch TJ, Grinstein S. A cation counterflux supports lysosomal acidification. The Journal of Cell Biology. 189: 1171-86. PMID 20566682 DOI: 10.1085/Jgp1362Oia2  0.383
2010 Bakowski MA, Braun V, Lam GY, Yeung T, Heo WD, Meyer T, Finlay BB, Grinstein S, Brumell JH. The phosphoinositide phosphatase SopB manipulates membrane surface charge and trafficking of the Salmonella-containing vacuole. Cell Host & Microbe. 7: 453-62. PMID 20542249 DOI: 10.1016/J.Chom.2010.05.011  0.782
2010 Gramoun A, Goto T, Nordström T, Rotstein OD, Grinstein S, Heersche JN, Manolson MF. Bone matrix proteins and extracellular acidification: potential co-regulators of osteoclast morphology. Journal of Cellular Biochemistry. 111: 350-61. PMID 20506338 DOI: 10.1002/Jcb.22705  0.546
2010 Braun V, Wong A, Landekic M, Hong WJ, Grinstein S, Brumell JH. Sorting nexin 3 (SNX3) is a component of a tubular endosomal network induced by Salmonella and involved in maturation of the Salmonella-containing vacuole. Cellular Microbiology. 12: 1352-67. PMID 20482551 DOI: 10.1111/J.1462-5822.2010.01476.X  0.645
2010 Leventis PA, Grinstein S. The distribution and function of phosphatidylserine in cellular membranes. Annual Review of Biophysics. 39: 407-27. PMID 20192774 DOI: 10.1146/Annurev.Biophys.093008.131234  0.385
2010 Koivusalo M, Welch C, Hayashi H, Scott CC, Kim M, Alexander T, Touret N, Hahn KM, Grinstein S. Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling. The Journal of Cell Biology. 188: 547-63. PMID 20156964 DOI: 10.1083/Jcb.200908086  0.368
2010 Lee JS, Lee YM, Kim JY, Park HW, Grinstein S, Orlowski J, Kim E, Kim KH, Lee MG. BetaPix up-regulates Na+/H+ exchanger 3 through a Shank2-mediated protein-protein interaction. The Journal of Biological Chemistry. 285: 8104-13. PMID 20080968 DOI: 10.1074/Jbc.M109.055079  0.444
2010 Casey JR, Grinstein S, Orlowski J. Sensors and regulators of intracellular pH. Nature Reviews. Molecular Cell Biology. 11: 50-61. PMID 19997129 DOI: 10.1038/Nrm2820  0.333
2010 Flannagan RS, Grinstein S. The application of fluorescent probes for the analysis of lipid dynamics during phagocytosis. Methods in Molecular Biology (Clifton, N.J.). 591: 121-34. PMID 19957127 DOI: 10.1007/978-1-60761-404-3_7  0.302
2010 Koivusalo M, Welch C, Hayashi H, Scott CC, Kim M, Alexander T, Touret N, Hahn KM, Grinstein S. Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling (Journal of Cell Biology (2010) 188, (547-563)) Journal of Cell Biology. 189: 385. DOI: 10.1083/Jcb.20090808620100331C  0.336
2010 Fairn G, Grinstein S. Phosphatidylserine polarization is required for proper Cdc42 localization and for development of cell polarity. Nature Precedings. 5: 1-1. DOI: 10.1038/Npre.2010.4232.1  0.341
2010 Golebiewska UP, Kay J, Grinstein S, Im W, Pastor R, Scarlata S, McLaughlin S. Don’t Fence Me in: Evidence for a ‘fence’ that Impedes the Diffusion of PIP2 Into and Out of Nascent Phagosomes in Macrophages Biophysical Journal. 98: 688a. DOI: 10.1016/J.Bpj.2009.12.3777  0.343
2009 Fairn GD, Ogata K, Botelho RJ, Stahl PD, Anderson RA, De Camilli P, Meyer T, Wodak S, Grinstein S. An electrostatic switch displaces phosphatidylinositol phosphate kinases from the membrane during phagocytosis. The Journal of Cell Biology. 187: 701-14. PMID 19951917 DOI: 10.1085/Jgp1351Oia1  0.776
2009 Collins RF, Touret N, Kuwata H, Tandon NN, Grinstein S, Trimble WS. Uptake of oxidized low density lipoprotein by CD36 occurs by an actin-dependent pathway distinct from macropinocytosis. The Journal of Biological Chemistry. 284: 30288-97. PMID 19740737 DOI: 10.1074/Jbc.M109.045104  0.316
2009 Fortier A, Doiron K, Saleh M, Grinstein S, Gros P. Restriction of Legionella pneumophila replication in macrophages requires concerted action of the transcriptional regulators Irf1 and Irf8 and nod-like receptors Naip5 and Nlrc4. Infection and Immunity. 77: 4794-805. PMID 19720760 DOI: 10.1128/Iai.01546-08  0.311
2009 Botelho RJ, Harrison RE, Stone JC, Hancock JF, Philips MR, Jongstra-Bilen J, Mason D, Plumb J, Gold MR, Grinstein S. Localized diacylglycerol-dependent stimulation of Ras and Rap1 during phagocytosis. The Journal of Biological Chemistry. 284: 28522-32. PMID 19700408 DOI: 10.1074/Jbc.M109.009514  0.63
2009 Yeung T, Heit B, Dubuisson JF, Fairn GD, Chiu B, Inman R, Kapus A, Swanson M, Grinstein S. Contribution of phosphatidylserine to membrane surface charge and protein targeting during phagosome maturation. The Journal of Cell Biology. 185: 917-28. PMID 19487458 DOI: 10.1085/Jgp1341Oia1  0.762
2009 Alexander RT, Grinstein S. Tethering, recycling and activation of the epithelial sodium-proton exchanger, NHE3. The Journal of Experimental Biology. 212: 1630-7. PMID 19448073 DOI: 10.1242/jeb.027375  0.327
2009 Flannagan RS, Cosío G, Grinstein S. Antimicrobial mechanisms of phagocytes and bacterial evasion strategies. Nature Reviews. Microbiology. 7: 355-66. PMID 19369951 DOI: 10.1038/Nrmicro2128  0.311
2009 Steinberg BE, Grinstein S. Analysis of macrophage phagocytosis: quantitative assays of phagosome formation and maturation using high-throughput fluorescence microscopy. Methods in Molecular Biology (Clifton, N.J.). 531: 45-56. PMID 19347310 DOI: 10.1007/978-1-59745-396-7_4  0.323
2009 Huang J, Canadien V, Lam GY, Steinberg BE, Dinauer MC, Magalhaes MA, Glogauer M, Grinstein S, Brumell JH. Activation of antibacterial autophagy by NADPH oxidases. Proceedings of the National Academy of Sciences of the United States of America. 106: 6226-31. PMID 19339495 DOI: 10.1073/Pnas.0811045106  0.748
2009 Wang Y, Roche O, Yan MS, Finak G, Evans AJ, Metcalf JL, Hast BE, Hanna SC, Wondergem B, Furge KA, Irwin MS, Kim WY, Teh BT, Grinstein S, Park M, et al. Regulation of endocytosis via the oxygen-sensing pathway. Nature Medicine. 15: 319-24. PMID 19252501 DOI: 10.1038/Nm.1922  0.319
2009 Li XJ, Tian W, Stull ND, Grinstein S, Atkinson S, Dinauer MC. A fluorescently tagged C-terminal fragment of p47phox detects NADPH oxidase dynamics during phagocytosis. Molecular Biology of the Cell. 20: 1520-32. PMID 19129478 DOI: 10.1091/Mbc.E08-06-0620  0.31
2009 Koivusalo M, Kapus A, Grinstein S. Sensors, transducers, and effectors that regulate cell size and shape. The Journal of Biological Chemistry. 284: 6595-9. PMID 19004817 DOI: 10.1074/Jbc.R800049200  0.505
2009 Sason H, Milgrom M, Weiss AM, Melamed-Book N, Balla T, Grinstein S, Backert S, Rosenshine I, Aroeti B. Enteropathogenic Escherichia coli subverts phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate upon epithelial cell infection. Molecular Biology of the Cell. 20: 544-55. PMID 18987340 DOI: 10.1091/Mbc.E08-05-0516  0.397
2009 Jaqaman K, Kuwata H, Trimble W, Grinstein S, Danuser G. Cortical Cytoskeletal Structures Constrain CD36 Receptor Motion at the Cell Surface to Enhance Aggregation and Signaling Biophysical Journal. 96: 281a-282a. DOI: 10.1016/J.Bpj.2008.12.1394  0.312
2008 Huynh KK, Gershenzon E, Grinstein S. Cholesterol accumulation by macrophages impairs phagosome maturation. The Journal of Biological Chemistry. 283: 35745-55. PMID 18955491 DOI: 10.1074/Jbc.M806232200  0.339
2008 Mallo GV, Espina M, Smith AC, Terebiznik MR, Alemán A, Finlay BB, Rameh LE, Grinstein S, Brumell JH. SopB promotes phosphatidylinositol 3-phosphate formation on Salmonella vacuoles by recruiting Rab5 and Vps34. The Journal of Cell Biology. 182: 741-52. PMID 18725540 DOI: 10.1083/Jcb.200804131  0.652
2008 Tian W, Li XJ, Stull ND, Ming W, Sun CI, Bissonnette SA, Yaffe MB, Grinstein S, Atkinson SJ, Dinauer MC. Fc{gamma}R-stimulated activation of the NADPH oxidase: Phosphoinositide- binding protein p40phox regulates NADPH oxidase activity after enzyme assembly on the phagosome Blood. 112: 3867-3877. PMID 18711001 DOI: 10.1182/Blood-2007-11-126029  0.343
2008 Huynh KK, Grinstein S. Phagocytosis: dynamin's dual role in phagosome biogenesis. Current Biology : Cb. 18: R563-5. PMID 18606127 DOI: 10.1016/J.Cub.2008.05.032  0.328
2008 Steinberg BE, Grinstein S. Pathogen destruction versus intracellular survival: the role of lipids as phagosomal fate determinants. The Journal of Clinical Investigation. 118: 2002-11. PMID 18523652 DOI: 10.1172/Jci35433  0.324
2008 Fairn GD, Grinstein S. Cell biology. A one-sided signal. Science (New York, N.Y.). 320: 458-60. PMID 18436763 DOI: 10.1126/Science.1158173  0.666
2008 Cosío G, Grinstein S. Analysis of phosphoinositide dynamics during phagocytosis using genetically encoded fluorescent biosensors. Methods in Molecular Biology (Clifton, N.J.). 445: 287-300. PMID 18425457 DOI: 10.1007/978-1-59745-157-4_18  0.366
2008 Huang YW, Yan M, Collins RF, Diciccio JE, Grinstein S, Trimble WS. Mammalian septins are required for phagosome formation. Molecular Biology of the Cell. 19: 1717-26. PMID 18272790 DOI: 10.1091/Mbc.E07-07-0641  0.423
2008 Yeung T, Gilbert GE, Shi J, Silvius J, Kapus A, Grinstein S. Membrane phosphatidylserine regulates surface charge and protein localization. Science (New York, N.Y.). 319: 210-3. PMID 18187657 DOI: 10.1126/Science.1152066  0.615
2008 Hayashi H, Aharonovitz O, Alexander RT, Touret N, Furuya W, Orlowski J, Grinstein S. Na+/H+ exchange and pH regulation in the control of neutrophil chemokinesis and chemotaxis. American Journal of Physiology. Cell Physiology. 294: C526-34. PMID 18094149 DOI: 10.1152/Ajpcell.00219.2007  0.398
2008 Steinberg BE, Huynh KK, Grinstein S. Phagosomal acidification: measurement, manipulation and functional consequences. Biochemical Society Transactions. 35: 1083-7. PMID 17956285 DOI: 10.1042/Bst0351083  0.38
2008 Steinberg BE, Brodovitch A, Huynh KK, Grinstein S. ROLE OF THE CYSTIC FIBROSIS TRANSMEMBRANE REGULATOR (CFTR) CHLORIDE CHANNEL IN MACROPHAGE LYSOSOME ACIDIFICATION Clinical & Investigative Medicine. 31: 23. DOI: 10.25011/Cim.V31I4.4828  0.388
2007 Huynh KK, Kay JG, Stow JL, Grinstein S. Fusion, fission, and secretion during phagocytosis. Physiology (Bethesda, Md.). 22: 366-72. PMID 18073409 DOI: 10.1152/Physiol.00028.2007  0.404
2007 Goldenberg NM, Grinstein S, Silverman M. Golgi-bound Rab34 is a novel member of the secretory pathway Molecular Biology of the Cell. 18: 4762-4771. PMID 17881736 DOI: 10.25011/Cim.V30I4.2854  0.432
2007 Yeung T, Grinstein S. Lipid signaling and the modulation of surface charge during phagocytosis. Immunological Reviews. 219: 17-36. PMID 17850479 DOI: 10.1111/J.1600-065X.2007.00546.X  0.424
2007 Huynh KK, Grinstein S. Regulation of vacuolar pH and its modulation by some microbial species. Microbiology and Molecular Biology Reviews : Mmbr. 71: 452-62. PMID 17804666 DOI: 10.1128/Mmbr.00003-07  0.341
2007 Orlowski J, Grinstein S. Emerging roles of alkali cation/proton exchangers in organellar homeostasis. Current Opinion in Cell Biology. 19: 483-92. PMID 17646094 DOI: 10.1016/J.Ceb.2007.06.001  0.361
2007 Steinberg BE, Touret N, Vargas-Caballero M, Grinstein S. In situ measurement of the electrical potential across the phagosomal membrane using FRET and its contribution to the proton-motive force. Proceedings of the National Academy of Sciences of the United States of America. 104: 9523-8. PMID 17517624 DOI: 10.1073/Pnas.0700783104  0.412
2007 Lee WL, Mason D, Schreiber AD, Grinstein S. Quantitative analysis of membrane remodeling at the phagocytic cup. Molecular Biology of the Cell. 18: 2883-92. PMID 17507658 DOI: 10.1091/Mbc.E06-05-0450  0.417
2007 Binker MG, Cosen-Binker LI, Terebiznik MR, Mallo GV, McCaw SE, Eskelinen EL, Willenborg M, Brumell JH, Saftig P, Grinstein S, Gray-Owen SD. Arrested maturation of Neisseria-containing phagosomes in the absence of the lysosome-associated membrane proteins, LAMP-1 and LAMP-2. Cellular Microbiology. 9: 2153-66. PMID 17506821 DOI: 10.1111/J.1462-5822.2007.00946.X  0.638
2007 Yan M, Di Ciano-Oliveira C, Grinstein S, Trimble WS. Coronin function is required for chemotaxis and phagocytosis in human neutrophils. Journal of Immunology (Baltimore, Md. : 1950). 178: 5769-78. PMID 17442961 DOI: 10.4049/Jimmunol.178.9.5769  0.367
2007 Steinberg BE, Grinstein S. Unconventional roles of the NADPH oxidase: signaling, ion homeostasis, and cell death. Science's Stke : Signal Transduction Knowledge Environment. 2007: pe11. PMID 17392241 DOI: 10.1126/Stke.3792007Pe11  0.311
2007 Mason D, Mallo GV, Terebiznik MR, Payrastre B, Finlay BB, Brumell JH, Rameh L, Grinstein S. Alteration of epithelial structure and function associated with PtdIns(4,5)P2 degradation by a bacterial phosphatase. The Journal of General Physiology. 129: 267-83. PMID 17389247 DOI: 10.1085/Jgp.200609656  0.712
2007 Lee WL, Cosio G, Ireton K, Grinstein S. Role of CrkII in Fcgamma receptor-mediated phagocytosis. The Journal of Biological Chemistry. 282: 11135-43. PMID 17308335 DOI: 10.1074/Jbc.M700823200  0.371
2007 Smith AC, Won DH, Braun V, Jiang X, Macrae C, Casanova JE, Scidmore MA, Grinstein S, Meyer T, Brumell JH. A network of Rab GTPases controls phagosome maturation and is modulated by Salmonella enterica serovar Typhimurium Journal of Cell Biology. 176: 263-268. PMID 17261845 DOI: 10.1083/Jcb.200611056  0.586
2007 Huynh KK, Eskelinen EL, Scott CC, Malevanets A, Saftig P, Grinstein S. LAMP proteins are required for fusion of lysosomes with phagosomes Embo Journal. 26: 313-324. PMID 17245426 DOI: 10.1038/Sj.Emboj.7601511  0.34
2007 Alexander RT, Malevanets A, Durkan AM, Kocinsky HS, Aronson PS, Orlowski J, Grinstein S. Membrane curvature alters the activation kinetics of the epithelial Na+/H+ exchanger, NHE3. The Journal of Biological Chemistry. 282: 7376-84. PMID 17218318 DOI: 10.1074/Jbc.M608557200  0.386
2007 Steinberg BE, Scott CC, Grinstein S. High-throughput assays of phagocytosis, phagosome maturation, and bacterial invasion American Journal of Physiology - Cell Physiology. 292. PMID 17020932 DOI: 10.1152/Ajpcell.00358.2006  0.34
2007 Lamothe J, Huynh KK, Grinstein S, Valvano MA. Intracellular survival of Burkholderia cenocepacia in macrophages is associated with a delay in the maturation of bacteria-containing vacuoles Cellular Microbiology. 9: 40-53. PMID 16869828 DOI: 10.1111/J.1462-5822.2006.00766.X  0.371
2007 Erdman L, Cosio G, Patel SN, Grinstein S, Kain KC. Innate inflammatory and phagocytic responses to Plasmodium falciparum: linked processes or molecularly discrete pathways?s Clinical & Investigative Medicine. 30: 81. DOI: 10.25011/Cim.V30I4.2851  0.315
2007 Mason D, Mallo GV, Terebiznik MR, Payrastre B, Finlay BB, Brumell JH, Rameh L, Grinstein S. Alteration of Epithelial Structure and Function Associated with PtdIns(4,5)P2Degradation by a Bacterial Phosphatase The Journal of Experimental Medicine. 204: i12-i12. DOI: 10.1084/Jem2044Oia12  0.521
2006 Mero P, Zhang CY, Huang ZY, Kim MK, Schreiber AD, Grinstein S, Booth JW. Phosphorylation-independent ubiquitylation and endocytosis of Fc gammaRIIA. The Journal of Biological Chemistry. 281: 33242-9. PMID 16959774 DOI: 10.1074/Jbc.M605372200  0.352
2006 Tan T, Lee WL, Alexander DC, Grinstein S, Liu J. The ESAT-6/CFP-10 secretion system of Mycobacterium marinum modulates phagosome maturation. Cellular Microbiology. 8: 1417-29. PMID 16922861 DOI: 10.1111/J.1462-5822.2006.00721.X  0.343
2006 Suh CI, Stull ND, Xing JL, Tian W, Price MO, Grinstein S, Yaffe MB, Atkinson S, Dinauer MC. The phosphoinositide-binding protein p40 phox activates the NADPH oxidase during FcγIIA receptor-induced phagocytosis Journal of Experimental Medicine. 203: 1915-1925. PMID 16880255 DOI: 10.1083/Jcb1744Oia8  0.357
2006 Yeung T, Terebiznik M, Yu L, Silvius J, Abidi WM, Philips M, Levine T, Kapus A, Grinstein S. Receptor activation alters inner surface potential during phagocytosis. Science (New York, N.Y.). 313: 347-51. PMID 16857939 DOI: 10.1126/Science.1129551  0.615
2006 Corbett-Nelson EF, Mason D, Marshall JG, Collette Y, Grinstein S. Signaling-dependent immobilization of acylated proteins in the inner monolayer of the plasma membrane. The Journal of Cell Biology. 174: 255-65. PMID 16831891 DOI: 10.1083/Jcb.200605044  0.379
2006 Yeung T, Ozdamar B, Paroutis P, Grinstein S. Lipid metabolism and dynamics during phagocytosis. Current Opinion in Cell Biology. 18: 429-37. PMID 16781133 DOI: 10.1016/J.Ceb.2006.06.006  0.37
2006 Touret N, Grinstein S. [Dynamic and functional characteristics of the phagosomal membrane]. Medecine Sciences : M/S. 22: 457-8. PMID 16687102 DOI: 10.1051/Medsci/2006225457  0.333
2006 Vachon E, Martin R, Plumb J, Kwok V, Vandivier RW, Glogauer M, Kapus A, Wang X, Chow CW, Grinstein S, Downey GP. CD44 is a phagocytic receptor. Blood. 107: 4149-58. PMID 16455948 DOI: 10.1182/Blood-2005-09-3808  0.568
2006 Martin-Orozco N, Touret N, Zaharik ML, Park E, Kopelman R, Miller S, Finlay BB, Gros P, Grinstein S. Visualization of vacuolar acidification-induced transcription of genes of pathogens inside macrophages. Molecular Biology of the Cell. 17: 498-510. PMID 16251362 DOI: 10.1091/Mbc.E04-12-1096  0.551
2006 Tian W, Li XJ, Stull ND, Suh C, Grinstein S, Yaffe MB, Atkinson SJ, Dinauer MC. The Phosphoinositide-Binding Protein p40phox Regulates NADPH Oxidase Activation Rather Than Assembly during FcγIIA Receptor-Induced Phagocytosis. Blood. 108: 678-678. DOI: 10.1182/Blood.V108.11.678.678  0.334
2005 Touret N, Paroutis P, Terebiznik M, Harrison RE, Trombetta S, Pypaert M, Chow A, Jiang A, Shaw J, Yip C, Moore HP, van der Wel N, Houben D, Peters PJ, de Chastellier C, ... ... Grinstein S, et al. Quantitative and dynamic assessment of the contribution of the ER to phagosome formation. Cell. 123: 157-70. PMID 16213220 DOI: 10.1016/J.Cell.2005.08.018  0.364
2005 Lam-Yuk-Tseung S, Touret N, Grinstein S, Gros P. Carboxyl-terminus determinants of the iron transporter DMT1/SLC11A2 isoform II (-IRE/1B) mediate internalization from the plasma membrane into recycling endosomes. Biochemistry. 44: 12149-59. PMID 16142913 DOI: 10.1021/Bi050911R  0.392
2005 Alexander RT, Furuya W, Szászi K, Orlowski J, Grinstein S. Rho GTPases dictate the mobility of the Na/H exchanger NHE3 in epithelia: role in apical retention and targeting. Proceedings of the National Academy of Sciences of the United States of America. 102: 12253-8. PMID 16103375 DOI: 10.1073/Pnas.0409197102  0.438
2005 Yeung T, Touret N, Grinstein S. Quantitative fluorescence microscopy to probe intracellular microenvironments. Current Opinion in Microbiology. 8: 350-8. PMID 15939361 DOI: 10.1016/J.Mib.2005.04.004  0.342
2005 Tse SM, Mason D, Botelho RJ, Chiu B, Reyland M, Hanada K, Inman RD, Grinstein S. Accumulation of diacylglycerol in the Chlamydia inclusion vacuole: possible role in the inhibition of host cell apoptosis. The Journal of Biological Chemistry. 280: 25210-5. PMID 15863503 DOI: 10.1074/Jbc.M501980200  0.65
2005 Yan M, Collins RF, Grinstein S, Trimble WS. Coronin-1 function is required for phagosome formation. Molecular Biology of the Cell. 16: 3077-87. PMID 15829569 DOI: 10.1091/Mbc.E04-11-0989  0.371
2005 Scott CC, Dobson W, Botelho RJ, Coady-Osberg N, Chavrier P, Knecht DA, Heath C, Stahl P, Grinstein S. Phosphatidylinositol-4,5-bisphosphate hydrolysis directs actin remodeling during phagocytosis. The Journal of Cell Biology. 169: 139-49. PMID 15809313 DOI: 10.1083/Jcb.200412162  0.657
2005 Touret N, Paroutis P, Grinstein S. The nature of the phagosomal membrane: endoplasmic reticulum versus plasmalemma. Journal of Leukocyte Biology. 77: 878-85. PMID 15728715 DOI: 10.1189/Jlb.1104630  0.361
2005 Lee WL, Kim MK, Schreiber AD, Grinstein S. Role of ubiquitin and proteasomes in phagosome maturation. Molecular Biology of the Cell. 16: 2077-90. PMID 15703218 DOI: 10.1091/Mbc.E04-06-0464  0.409
2004 Chow CW, Downey GP, Grinstein S. Measurements of phagocytosis and phagosomal maturation. Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit 15.7. PMID 18228442 DOI: 10.1002/0471143030.Cb1507S22  0.345
2004 Paroutis P, Touret N, Grinstein S. The pH of the secretory pathway: measurement, determinants, and regulation. Physiology (Bethesda, Md.). 19: 207-15. PMID 15304635 DOI: 10.1152/Physiol.00005.2004  0.324
2004 Touret N, Martin-Orozco N, Paroutis P, Furuya W, Lam-Yuk-Tseung S, Forbes J, Gros P, Grinstein S. Molecular and cellular mechanisms underlying iron transport deficiency in microcytic anemia. Blood. 104: 1526-33. PMID 15155465 DOI: 10.1182/Blood-2004-02-0731  0.305
2004 Harrison RE, Brumell JH, Khandani A, Bucci C, Scott CC, Jiang X, Finlay BB, Grinstein S. Salmonella impairs RILP recruitment to Rab7 during maturation of invasion vacuoles. Molecular Biology of the Cell. 15: 3146-54. PMID 15121880 DOI: 10.1091/Mbc.E04-02-0092  0.706
2004 Vieira OV, Harrison RE, Scott CC, Stenmark H, Alexander D, Liu J, Gruenberg J, Schreiber AD, Grinstein S. Acquisition of Hrs, an essential component of phagosomal maturation, is impaired by mycobacteria. Molecular and Cellular Biology. 24: 4593-604. PMID 15121875 DOI: 10.1128/Mcb.24.10.4593-4604.2004  0.371
2004 Hayashi H, Szászi K, Coady-Osberg N, Furuya W, Bretscher AP, Orlowski J, Grinstein S. Inhibition and redistribution of NHE3, the apical Na+/H+ exchanger, by Clostridium difficile toxin B. The Journal of General Physiology. 123: 491-504. PMID 15078917 DOI: 10.1085/Jgp.200308979  0.39
2004 Brumell JH, Grinstein S. Salmonella redirects phagosomal maturation. Current Opinion in Microbiology. 7: 78-84. PMID 15036145 DOI: 10.1016/J.Mib.2003.12.005  0.578
2004 Botelho RJ, Scott CC, Grinstein S. Phosphoinositide involvement in phagocytosis and phagosome maturation. Current Topics in Microbiology and Immunology. 282: 1-30. PMID 14594212 DOI: 10.1007/978-3-642-18805-3_1  0.654
2004 Orlowski J, Grinstein S. Diversity of the mammalian sodium/proton exchanger SLC9 gene family. PflüGers Archiv : European Journal of Physiology. 447: 549-65. PMID 12845533 DOI: 10.1007/S00424-003-1110-3  0.412
2004 Suh CI, Stull N, Fuji Y, Grinstein S, Yaffe M, Atkinson S, Dinauer MC. Role for p40phox in Fcγ-Receptor-Induced NADPH Oxidase Activation. Blood. 104: 653-653. DOI: 10.1182/Blood.V104.11.653.653  0.44
2003 Lee WL, Harrison RE, Grinstein S. Phagocytosis by neutrophils. Microbes and Infection / Institut Pasteur. 5: 1299-306. PMID 14613773 DOI: 10.1016/J.Micinf.2003.09.014  0.369
2003 Scott CC, Botelho RJ, Grinstein S. Phagosome maturation: a few bugs in the system. The Journal of Membrane Biology. 193: 137-52. PMID 12962275 DOI: 10.1007/S00232-002-2008-2  0.669
2003 Harrison RE, Bucci C, Vieira OV, Schroer TA, Grinstein S. Phagosomes fuse with late endosomes and/or lysosomes by extension of membrane protrusions along microtubules: role of Rab7 and RILP. Molecular and Cellular Biology. 23: 6494-506. PMID 12944476 DOI: 10.1128/Mcb.23.18.6494-6506.2003  0.378
2003 Jongstra-Bilen J, Harrison R, Grinstein S. Fcgamma-receptors induce Mac-1 (CD11b/CD18) mobilization and accumulation in the phagocytic cup for optimal phagocytosis. The Journal of Biological Chemistry. 278: 45720-9. PMID 12941957 DOI: 10.1074/Jbc.M303704200  0.383
2003 Gu H, Botelho RJ, Yu M, Grinstein S, Neel BG. Critical role for scaffolding adapter Gab2 in FcγR-mediated phagocytosis Journal of Cell Biology. 161: 1151-1161. PMID 12821647 DOI: 10.1083/Jcb.200212158  0.675
2003 Scott CC, Furuya W, Trimble WS, Grinstein S. Activation of store-operated calcium channels: assessment of the role of snare-mediated vesicular transport. The Journal of Biological Chemistry. 278: 30534-9. PMID 12764154 DOI: 10.1074/Jbc.M304718200  0.408
2003 Touret N, Furuya W, Forbes J, Gros P, Grinstein S. Dynamic traffic through the recycling compartment couples the metal transporter Nramp2 (DMT1) with the transferrin receptor. The Journal of Biological Chemistry. 278: 25548-57. PMID 12724326 DOI: 10.1074/Jbc.M212374200  0.413
2003 Brumell JH, Grinstein S. Role of lipid-mediated signal transduction in bacterial internalization. Cellular Microbiology. 5: 287-97. PMID 12713488 DOI: 10.1046/J.1462-5822.2003.00273.X  0.618
2003 Jabado N, Cuellar-Mata P, Grinstein S, Gros P. Iron chelators modulate the fusogenic properties of Salmonella-containing phagosomes. Proceedings of the National Academy of Sciences of the United States of America. 100: 6127-32. PMID 12711734 DOI: 10.1073/Pnas.0937287100  0.363
2003 Benharouga M, Sharma M, So J, Haardt M, Drzymala L, Popov M, Schwapach B, Grinstein S, Du K, Lukacs GL. The role of the C terminus and Na+/H+ exchanger regulatory factor in the functional expression of cystic fibrosis transmembrane conductance regulator in nonpolarized cells and epithelia. The Journal of Biological Chemistry. 278: 22079-89. PMID 12651858 DOI: 10.1074/Jbc.M301030200  0.386
2003 Vieira OV, Bucci C, Harrison RE, Trimble WS, Lanzetti L, Gruenberg J, Schreiber AD, Stahl PD, Grinstein S. Modulation of Rab5 and Rab7 recruitment to phagosomes by phosphatidylinositol 3-kinase. Molecular and Cellular Biology. 23: 2501-14. PMID 12640132 DOI: 10.1128/Mcb.23.7.2501-2514.2003  0.411
2003 Booth JW, Telio D, Liao EH, McCaw SE, Matsuo T, Grinstein S, Gray-Owen SD. Phosphatidylinositol 3-kinases in carcinoembryonic antigen-related cellular adhesion molecule-mediated internalization of Neisseria gonorrhoeae. The Journal of Biological Chemistry. 278: 14037-45. PMID 12571236 DOI: 10.1074/Jbc.M211879200  0.414
2003 Dombrosky-Ferlan P, Grishin A, Botelho RJ, Sampson M, Wang L, Rudert WA, Grinstein S, Corey SJ. Felic (CIP4b), a novel binding partner with the Src kinase Lyn and Cdc42, localizes to the phagocytic cup. Blood. 101: 2804-9. PMID 12456510 DOI: 10.1182/Blood-2002-03-0851  0.644
2002 Hayashi H, Szászi K, Grinstein S. Multiple modes of regulation of Na+/H+ exchangers. Annals of the New York Academy of Sciences. 976: 248-58. PMID 12502567 DOI: 10.1111/J.1749-6632.2002.Tb04747.X  0.386
2002 Harrison RE, Grinstein S. Phagocytosis and the microtubule cytoskeleton. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 80: 509-15. PMID 12440692 DOI: 10.1139/O02-142  0.36
2002 Botelho RJ, Tapper H, Furuya W, Mojdami D, Grinstein S. Fc gamma R-mediated phagocytosis stimulates localized pinocytosis in human neutrophils. Journal of Immunology (Baltimore, Md. : 1950). 169: 4423-9. PMID 12370376 DOI: 10.4049/Jimmunol.169.8.4423  0.661
2002 Terebiznik MR, Vieira OV, Marcus SL, Slade A, Yip CM, Trimble WS, Meyer T, Finlay BB, Grinstein S. Elimination of host cell PtdIns(4,5)P(2) by bacterial SigD promotes membrane fission during invasion by Salmonella. Nature Cell Biology. 4: 766-73. PMID 12360287 DOI: 10.1038/Ncb854  0.549
2002 Collins RF, Schreiber AD, Grinstein S, Trimble WS. Syntaxins 13 and 7 function at distinct steps during phagocytosis. Journal of Immunology (Baltimore, Md. : 1950). 169: 3250-6. PMID 12218144 DOI: 10.4049/Jimmunol.169.6.3250  0.393
2002 Szaszi K, Paulsen A, Szabo EZ, Numata M, Grinstein S, Orlowski J. Clathrin-mediated endocytosis and recycling of the neuron-specific Na+/H+ exchanger NHE5 isoform. Regulation by phosphatidylinositol 3'-kinase and the actin cytoskeleton. The Journal of Biological Chemistry. 277: 42623-32. PMID 12205089 DOI: 10.1074/Jbc.M206629200  0.431
2002 Canonne-Hergaux F, Calafat J, Richer E, Cellier M, Grinstein S, Borregaard N, Gros P. Expression and subcellular localization of NRAMP1 in human neutrophil granules Blood. 100: 268-275. PMID 12070036 DOI: 10.1182/Blood.V100.1.268  0.365
2002 Vieira OV, Botelho RJ, Grinstein S. Phagosome maturation: aging gracefully. The Biochemical Journal. 366: 689-704. PMID 12061891 DOI: 10.1042/Bj20020691  0.644
2002 Tapper H, Furuya W, Grinstein S. Localized exocytosis of primary (lysosomal) granules during phagocytosis: role of Ca2+-dependent tyrosine phosphorylation and microtubules. Journal of Immunology (Baltimore, Md. : 1950). 168: 5287-96. PMID 11994486 DOI: 10.4049/Jimmunol.168.10.5287  0.353
2002 Jankowski A, Grinstein S. Modulation of the cytosolic and phagosomal pH by the NADPH oxidase. Antioxidants & Redox Signaling. 4: 61-8. PMID 11970844 DOI: 10.1089/152308602753625861  0.711
2002 Booth JW, Kim MK, Jankowski A, Schreiber AD, Grinstein S. Contrasting requirements for ubiquitylation during Fc receptor-mediated endocytosis and phagocytosis. The Embo Journal. 21: 251-8. PMID 11823418 DOI: 10.1093/Emboj/21.3.251  0.713
2002 Greenberg S, Grinstein S. Phagocytosis and innate immunity. Current Opinion in Immunology. 14: 136-45. PMID 11790544 DOI: 10.1016/S0952-7915(01)00309-0  0.38
2002 Jankowski A, Scott CC, Grinstein S. Determinants of the phagosomal pH in neutrophils Journal of Biological Chemistry. 277: 6059-6066. PMID 11744729 DOI: 10.1074/Jbc.M110059200  0.741
2002 Nauclér C, Grinstein S, Sundler R, Tapper H. Signaling to localized degranulation in neutrophils adherent to immune complexes Journal of Leukocyte Biology. 71: 701-710. DOI: 10.1189/Jlb.71.4.701  0.388
2001 Booth JW, Trimble WS, Grinstein S. Membrane dynamics in phagocytosis Seminars in Immunology. 13: 357-364. PMID 11708891 DOI: 10.1006/Smim.2001.0332  0.365
2001 Cuellar-Mata P, Jabado N, Liu J, Furuya W, Finlay BB, Gros P, Grinstein S. Nramp1 modifies the fusion of Salmonella typhimurium-containing vacuoles with cellular endomembranes in macrophages. The Journal of Biological Chemistry. 277: 2258-65. PMID 11700301 DOI: 10.1074/jbc.M105508200  0.506
2001 Vieira OV, Botelho RJ, Rameh L, Brachmann SM, Matsuo T, Davidson HW, Schreiber A, Backer JM, Cantley LC, Grinstein S. Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation. The Journal of Cell Biology. 155: 19-25. PMID 11581283 DOI: 10.1083/Jcb.200107069  0.643
2001 Marshall JG, Booth JW, Stambolic V, Mak T, Balla T, Schreiber AD, Meyer T, Grinstein S. Restricted accumulation of phosphatidylinositol 3-kinase products in a plasmalemmal subdomain during Fcγ receptor-mediated phagocytosis Journal of Cell Biology. 153: 1369-1380. PMID 11425868 DOI: 10.1083/Jcb.153.7.1369  0.437
2001 Gillis D, Shrode LD, Krump E, Howard CM, Rubie EA, Tibbles LA, Woodgett J, Grinstein S. Osmotic stimulation of the Na+/H+ exchanger NHE1: relationship to the activation of three MAPK pathways. The Journal of Membrane Biology. 181: 205-14. PMID 11420607 DOI: 10.1007/S00232-001-0023-3  0.358
2001 Aharonovitz O, Kapus A, Szászi K, Coady-Osberg N, Jancelewicz T, Orlowski J, Grinstein S. Modulation of Na+/H+ exchange activity by Cl- American Journal of Physiology - Cell Physiology. 281. PMID 11401835 DOI: 10.1152/Ajpcell.2001.281.1.C133  0.614
2001 Hackam DJ, Botelho RJ, Sjolin C, Rotstein OD, Robinson JM, Schreiber AD, Grinstein S. Indirect role for COPI in the completion of FCgamma receptor-mediated phagocytosis. The Journal of Biological Chemistry. 276: 18200-8. PMID 11279223 DOI: 10.1074/jbc.M102009200  0.722
2001 Coppolino MG, Kong C, Mohtashami M, Schreiber AD, Brumell JH, Finlay BB, Grinstein S, Trimble WS. Requirement for N-ethylmaleimide-sensitive factor activity at different stages of bacterial invasion and phagocytosis. The Journal of Biological Chemistry. 276: 4772-80. PMID 11092884 DOI: 10.1074/Jbc.M007792200  0.694
2000 Botelho RJ, Teruel M, Dierckman R, Anderson R, Wells A, York JD, Meyer T, Grinstein S. Localized biphasic changes in phosphatidylinositol-4,5-bisphosphate at sites of phagocytosis. The Journal of Cell Biology. 151: 1353-68. PMID 11134066 DOI: 10.1083/Jcb.151.7.1353  0.671
2000 Szászi K, Grinstein S, Orlowski J, Kapus A. Regulation of the epithelial Na+/H+ exchanger isoform by the cytoskeleton Cellular Physiology and Biochemistry. 10: 265-272. PMID 11125205 DOI: 10.1159/000016358  0.648
2000 Kruger J, Butler JR, Cherapanov V, Dong Q, Ginzberg H, Govindarajan A, Grinstein S, Siminovitch KA, Downey GP. Deficiency of Src homology 2-containing phosphatase 1 results in abnormalities in murine neutrophil function: studies in motheaten mice. Journal of Immunology (Baltimore, Md. : 1950). 165: 5847-59. PMID 11067945 DOI: 10.4049/Jimmunol.165.10.5847  0.372
2000 Jabado N, Jankowski A, Dougaparsad S, Picard V, Grinstein S, Gros P. Natural resistance to intracellular infections: natural resistance-associated macrophage protein 1 (Nramp1) functions as a pH-dependent manganese transporter at the phagosomal membrane. The Journal of Experimental Medicine. 192: 1237-48. PMID 11067873 DOI: 10.1084/Jem.192.9.1237  0.417
2000 Aharonovitz O, Zaun HC, Balla T, York JD, Orlowski J, Grinstein S. Intracellular pH regulation by Na(+)/H(+) exchange requires phosphatidylinositol 4,5-bisphosphate. The Journal of Cell Biology. 150: 213-24. PMID 10893269 DOI: 10.1083/Jcb.150.1.213  0.417
2000 Bajno L, Peng XR, Schreiber AD, Moore HP, Trimble WS, Grinstein S. Focal exocytosis of VAMP3-containing vesicles at sites of phagosome formation. The Journal of Cell Biology. 149: 697-706. PMID 10791982 DOI: 10.1083/Jcb.149.3.697  0.418
2000 Botelho RJ, Hackam DJ, Schreiber AD, Grinstein S. Role of COPI in phagosome maturation. The Journal of Biological Chemistry. 275: 15717-27. PMID 10748188 DOI: 10.1074/Jbc.M910068199  0.655
2000 Schapiro FB, Grinstein S. Determinants of the pH of the Golgi complex. The Journal of Biological Chemistry. 275: 21025-32. PMID 10748071 DOI: 10.1074/Jbc.M002386200  0.794
2000 Schapiro F, Sparkowski J, Adduci A, Suprynowicz F, Schlegel R, Grinstein S. Golgi alkalinization by the papillomavirus E5 oncoprotein. The Journal of Cell Biology. 148: 305-15. PMID 10648563 DOI: 10.1083/Jcb.148.2.305  0.788
1999 Chow CW, Khurana S, Woodside M, Grinstein S, Orlowski J. The epithelial Na(+)/H(+) exchanger, NHE3, is internalized through a clathrin-mediated pathway. The Journal of Biological Chemistry. 274: 37551-8. PMID 10608808 DOI: 10.1074/Jbc.274.53.37551  0.31
1999 Zhang J, Kong C, Xie H, McPherson PS, Grinstein S, Trimble WS. Phosphatidylinositol polyphosphate binding to the mammalian septin H5 is modulated by GTP. Current Biology : Cb. 9: 1458-67. PMID 10607590 DOI: 10.1016/S0960-9822(00)80115-3  0.369
1999 Plant PJ, Manolson MF, Grinstein S, Demaurex N. Alternative mechanisms of vacuolar acidification in H+-ATPase-deficient yeast Journal of Biological Chemistry. 274: 37270-37279. PMID 10601292 DOI: 10.1074/Jbc.274.52.37270  0.735
1999 Zhang J, Shehabeldin A, da Cruz LA, Butler J, Somani AK, McGavin M, Kozieradzki I, dos Santos AO, Nagy A, Grinstein S, Penninger JM, Siminovitch KA. Antigen receptor-induced activation and cytoskeletal rearrangement are impaired in Wiskott-Aldrich syndrome protein-deficient lymphocytes. The Journal of Experimental Medicine. 190: 1329-42. PMID 10544204 DOI: 10.1084/Jem.190.9.1329  0.351
1999 Yusta B, Somwar R, Wang F, Munroe D, Grinstein S, Klip A, Drucker DJ. Identification of glucagon-like peptide-2 (GLP-2)-activated signaling pathways in baby hamster kidney fibroblasts expressing the rat GLP-2 receptor. The Journal of Biological Chemistry. 274: 30459-67. PMID 10521425 DOI: 10.1074/jbc.274.43.30459  0.616
1999 Kurashia K, D'Souza S, Szászi K, Ramjeesingh R, Orlowski J, Grinstein S. The apical Na+/H+ exchanger isoform NHE3 is regulated by the actin cytoskeleton Journal of Biological Chemistry. 274: 29843-29849. PMID 10514464 DOI: 10.1074/Jbc.274.42.29843  0.369
1999 Downey GP, Botelho RJ, Butler JR, Moltyaner Y, Chien P, Schreiber AD, Grinstein S. Phagosomal maturation, acidification, and inhibition of bacterial growth in nonphagocytic cells transfected with FcgammaRIIA receptors. The Journal of Biological Chemistry. 274: 28436-44. PMID 10497205 DOI: 10.1074/Jbc.274.40.28436  0.657
1999 Jankowski A, Grinstein S. A noninvasive fluorimetric procedure for measurement of membrane potential. Quantification of the NADPH oxidase-induced depolarization in activated neutrophils. The Journal of Biological Chemistry. 274: 26098-104. PMID 10473559 DOI: 10.1074/Jbc.274.37.26098  0.732
1999 Wieczorek H, Brown D, Grinstein S, Ehrenfeld J, Harvey WR. Animal plasma membrane energization by proton-motive V-ATPases. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 21: 637-48. PMID 10440860 DOI: 10.1002/(Sici)1521-1878(199908)21:8<637::Aid-Bies3>3.0.Co;2-W  0.387
1999 Wiemann M, Schwark JR, Bonnet U, Jansen HW, Grinstein S, Baker RE, Lang HJ, Wirth K, Bingmann D. Selective inhibition of the Na+/H+ exchanger type 3 activates CO2/H+-sensitive medullary neurones Pflugers Archiv European Journal of Physiology. 438: 255-262. PMID 10398853 DOI: 10.1007/S004240050907  0.302
1999 Aharonovitz O, Demaurex N, Woodside M, Grinstein S. ATP dependence is not an intrinsic property of Na+/H+ exchanger NHE1: requirement for an ancillary factor. The American Journal of Physiology. 276: C1303-11. PMID 10362593 DOI: 10.1152/Ajpcell.1999.276.6.C1303  0.309
1999 Govoni G, Canonne-Hergaux F, Pfeifer CG, Marcus SL, Mills SD, Hackam DJ, Grinstein S, Malo D, Finlay BB, Gros P. Functional expression of Nramp1 in vitro in the murine macrophage line RAW264.7. Infection and Immunity. 67: 2225-32. PMID 10225878 DOI: 10.1128/Iai.67.5.2225-2232.1999  0.56
1999 Chow CW, Woodside M, Demaurex N, Yu FH, Plant P, Rotin D, Grinstein S, Orlowski J. Proline-rich motifs of the Na+/H+ exchanger 2 isoform. Binding of Src homology domain 3 and role in apical targeting in epithelia. The Journal of Biological Chemistry. 274: 10481-8. PMID 10187839 DOI: 10.1074/Jbc.274.15.10481  0.782
1999 Gruenheid S, Canonne-Hergaux F, Gauthier S, Hackam DJ, Grinstein S, Gros P. The iron transport protein NRAMP2 is an integral membrane glycoprotein that colocalizes with transferrin in recycling endosomes. The Journal of Experimental Medicine. 189: 831-41. PMID 10049947 DOI: 10.1084/Jem.189.5.831  0.375
1999 Petrecca K, Atanasiu R, Grinstein S, Orlowski J, Shrier A. Subcellular localization of the Na+/H+ exchanger NHE1 in rat myocardium. The American Journal of Physiology. 276: H709-17. PMID 9950874 DOI: 10.1152/Ajpheart.1999.276.2.H709  0.367
1999 Shrode LD, Krump E, Grinstein S. Activation of protein kinases upon volume changes: role in cellular homeostasis. Contributions to Nephrology. 123: 79-93. PMID 9761962 DOI: 10.1159/000059922  0.309
1999 Hackam DJ, Rotstein OD, Grinstein S. Phagosomal acidification mechanisms and functional significance Advances in Cellular and Molecular Biology of Membranes and Organelles. 5: 299-319. DOI: 10.1016/S1874-5172(99)80037-6  0.569
1998 Gan BS, Krump E, Shrode LD, Grinstein S. Loading pyranine via purinergic receptors or hypotonic stress for measurement of cytosolic pH by imaging. The American Journal of Physiology. 275: C1158-66. PMID 9755070 DOI: 10.1152/Ajpcell.1998.275.4.C1158  0.329
1998 Hackam DJ, Rotstein OD, Sjolin C, Schreiber AD, Trimble WS, Grinstein S. v-SNARE-dependent secretion is required for phagocytosis. Proceedings of the National Academy of Sciences of the United States of America. 95: 11691-6. PMID 9751727 DOI: 10.1073/Pnas.95.20.11691  0.571
1998 Kurashima K, Szabó EZ, Lukacs G, Orlowski J, Grinstein S. Endosomal recycling of the Na+/H+ exchanger NHE3 isoform is regulated by the phosphatidylinositol 3-kinase pathway. The Journal of Biological Chemistry. 273: 20828-36. PMID 9694828 DOI: 10.1074/Jbc.273.33.20828  0.417
1998 Shrode LD, Gan BS, D'Souza SJA, Orlowski J, Grinstein S. Topological analysis of NHE1, the ubiquitous Na+/H+ exchanger using chymotryptic cleavage American Journal of Physiology - Cell Physiology. 275. PMID 9688597 DOI: 10.1152/Ajpcell.1998.275.2.C431  0.38
1998 Hackam DJ, Rotstein OD, Zhang W, Gruenheid S, Gros P, Grinstein S. Host resistance to intracellular infection: mutation of natural resistance-associated macrophage protein 1 (Nramp1) impairs phagosomal acidification. The Journal of Experimental Medicine. 188: 351-64. PMID 9670047 DOI: 10.1084/Jem.188.2.351  0.599
1998 Kiefer F, Brumell J, Al-Alawi N, Latour S, Cheng A, Veillette A, Grinstein S, Pawson T. The Syk protein tyrosine kinase is essential for Fcgamma receptor signaling in macrophages and neutrophils. Molecular and Cellular Biology. 18: 4209-20. PMID 9632805 DOI: 10.1128/Mcb.18.7.4209  0.608
1998 Anderie I, Blum R, Haase W, Grinstein S, Thévenod F. Expression of NHE1 and NHE4 in rat pancreatic zymogen granule membranes. Biochemical and Biophysical Research Communications. 246: 330-6. PMID 9610358 DOI: 10.1006/Bbrc.1998.8611  0.352
1998 Hall RA, Premont RT, Chow CW, Blitzer JT, Pitcher JA, Claing A, Stoffel RH, Barak LS, Shenolikar S, Weinman EJ, Grinstein S, Lefkowitz RJ. The beta2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange. Nature. 392: 626-30. PMID 9560162 DOI: 10.1038/33458  0.321
1998 Kim JH, Johannes L, Goud B, Antony C, Lingwood CA, Daneman R, Grinstein S. Noninvasive measurement of the pH of the endoplasmic reticulum at rest and during calcium release. Proceedings of the National Academy of Sciences of the United States of America. 95: 2997-3002. PMID 9501204 DOI: 10.1073/Pnas.95.6.2997  0.356
1998 Schapiro FB, Lingwood C, Furuya W, Grinstein S. pH-independent retrograde targeting of glycolipids to the Golgi complex. The American Journal of Physiology. 274: C319-32. PMID 9486120 DOI: 10.1152/Ajpcell.1998.274.2.C319  0.811
1998 D'Souza S, Garcia-Cabado A, Yu F, Teter K, Lukacs G, Skorecki K, Moore HP, Orlowski J, Grinstein S. The epithelial sodium-hydrogen antiporter Na+/H+ exchanger 3 accumulates and is functional in recycling endosomes. The Journal of Biological Chemistry. 273: 2035-43. PMID 9442041 DOI: 10.1074/Jbc.273.4.2035  0.346
1998 Shrode LD, Tapper H, Grinstein S. Role of intracellular pH in proliferation, transformation, and apoptosis. Journal of Bioenergetics and Biomembranes. 29: 393-9. PMID 9387100 DOI: 10.1023/A:1022407116339  0.334
1998 Lukacs GL, Segal G, Kartner N, Grinstein S, Zhang F. Constitutive internalization of cystic fibrosis transmembrane conductance regulator occurs via clathrin-dependent endocytosis and is regulated by protein phosphorylation. The Biochemical Journal. 353-61. PMID 9371688 DOI: 10.1042/Bj3280353  0.435
1997 Hackam DJ, Rotstein OD, Zhang WJ, Demaurex N, Woodside M, Tsai O, Grinstein S. Regulation of phagosomal acidification. Differential targeting of Na +/H + exchangers, Na +/K +-ATPases, and vacuolar-type H +-ATPases Journal of Biological Chemistry. 272: 29810-29820. PMID 9368053 DOI: 10.1074/Jbc.272.47.29810  0.601
1997 Kurashima K, Yu FH, Cabado AG, Szabó EZ, Grinstein S, Orlowski J. Identification of sites required for down-regulation of Na+/H+ exchanger NHE3 activity by cAMP-dependent protein kinase. phosphorylation-dependent and -independent mechanisms. The Journal of Biological Chemistry. 272: 28672-9. PMID 9353335 DOI: 10.1074/Jbc.272.45.28672  0.361
1997 Orlowski J, Grinstein S. Na+/H+ exchangers of mammalian cells. The Journal of Biological Chemistry. 272: 22373-6. PMID 9278382 DOI: 10.1074/Jbc.272.36.22373  0.311
1997 Chow CW, Kapus A, Romanek R, Grinstein S. NO3--induced pH changes in mammalian cells. Evidence for an NO3--H+ cotransporter. The Journal of General Physiology. 110: 185-200. PMID 9236211 DOI: 10.1085/Jgp.110.2.185  0.602
1997 Krump E, Nikitas K, Grinstein S. Induction of tyrosine phosphorylation and Na+/H+ exchanger activation during shrinkage of human neutrophils. The Journal of Biological Chemistry. 272: 17303-11. PMID 9211867 DOI: 10.1074/Jbc.272.28.17303  0.367
1997 Sue-A-Quan AK, Fialkow L, Vlahos CJ, Schelm JA, Grinstein S, Butler J, Downey GP. Inhibition of neutrophil oxidative burst and granule secretion by wortmannin: potential role of MAP kinase and renaturable kinases. Journal of Cellular Physiology. 172: 94-108. PMID 9207930 DOI: 10.1002/(Sici)1097-4652(199707)172:1<94::Aid-Jcp11>3.0.Co;2-O  0.333
1997 Dackiw AP, Grinstein S, Brisseau GF, McGilvray ID, Nathens AB, McGuire JA, Romanek R, Cheung PY, Rotstein OD. The role of tyrosine phosphorylation in lipopolysaccharide- and zymosan-induced procoagulant activity and tissue factor expression in macrophages. Infection and Immunity. 65: 2362-70. PMID 9169775 DOI: 10.1128/Iai.65.6.2362-2370.1997  0.656
1997 Coppolino MG, Woodside MJ, Demaurex N, Grinstein S, St-Arnaud R, Dedhar S. Calreticulin is essential for integrin-mediated calcium signalling and cell adhesion. Nature. 386: 843-7. PMID 9126744 DOI: 10.1038/386843A0  0.334
1997 Mohamed A, Ferguson D, Seibert FS, Cai HM, Kartner N, Grinstein S, Riordan JR, Lukacs GL. Functional expression and apical localization of the cystic fibrosis transmembrane conductance regulator in MDCK I cells. The Biochemical Journal. 259-65. PMID 9078271 DOI: 10.1042/Bj3220259  0.364
1997 Nordström T, Shrode LD, Rotstein OD, Romanek R, Goto T, Heersche JN, Manolson MF, Brisseau GF, Grinstein S. Chronic extracellular acidosis induces plasmalemmal vacuolar type H+ ATPase activity in osteoclasts. The Journal of Biological Chemistry. 272: 6354-60. PMID 9045656 DOI: 10.1074/Jbc.272.10.6354  0.566
1997 Demaurex N, Romanek RR, Orlowski J, Grinstein S. ATP dependence of Na+/H+ exchange. Nucleotide specificity and assessment of the role of phospholipids. The Journal of General Physiology. 109: 117-28. PMID 9041442 DOI: 10.1085/Jgp.109.2.117  0.374
1997 Shago M, Flock G, Leung Hagesteijn CY, Woodside M, Grinstein S, Giguère V, Dedhar S. Modulation of the retinoic acid and retinoid X receptor signaling pathways in P19 embryonal carcinoma cells by calreticulin. Experimental Cell Research. 230: 50-60. PMID 9013706 DOI: 10.1006/Excr.1996.3408  0.325
1997 Krump E, Sanghera JS, Pelech SL, Furuya W, Grinstein S. Chemotactic peptide N-formyl-met-leu-phe activation of p38 mitogen-activated protein kinase (MAPK) and MAPK-activated protein kinase-2 in human neutrophils. The Journal of Biological Chemistry. 272: 937-44. PMID 8995385 DOI: 10.1074/Jbc.272.2.937  0.32
1997 Brumell JH, Chan CK, Butler J, Borregaard N, Siminovitch KA, Grinstein S, Downey GP. Regulation of Src homology 2-containing tyrosine phosphatase 1 during activation of human neutrophils: Role of protein kinase C Journal of Biological Chemistry. 272: 875-882. PMID 8995376 DOI: 10.1074/Jbc.272.2.875  0.605
1997 Robertson MA, Woodside M, Foskett JK, Orlowski J, Grinstein S. Muscarinic agonists induce phosphorylation-independent activation of the NHE-1 isoform of the Na+/H+ antiporter in salivary acinar cells. The Journal of Biological Chemistry. 272: 287-94. PMID 8995260 DOI: 10.1074/Jbc.272.1.287  0.43
1996 Goss G, Orlowski J, Grinstein S. Coimmunoprecipitation of a 24-kDa protein with NHE1, the ubiquitous isoform of the Na+/H+ exchanger. The American Journal of Physiology. 270: C1493-502. PMID 8967452 DOI: 10.1152/Ajpcell.1996.270.5.C1493  0.326
1996 Kim JH, Lingwood CA, Williams DB, Furuya W, Manolson MF, Grinstein S. Dynamic measurement of the pH of the Golgi complex in living cells using retrograde transport of the verotoxin receptor Journal of Cell Biology. 134: 1387-1399. PMID 8830769 DOI: 10.1083/Jcb.134.6.1387  0.413
1996 Hackam DJ, Grinstein S, Rotstein OD. Intracellular pH regulation in leukocytes: Mechanisms and functional significance Shock. 5: 17-21. PMID 8821098 DOI: 10.1097/00024382-199601000-00005  0.589
1996 Downey GP, Butler JR, Brumell J, Borregaard N, Kjeldsen L, Sue-A-Quan AK, Grinstein S. Chemotactic peptide-induced activation of MEK-2, the predominant isoform in human neutrophils. Inhibition by wortmannin. The Journal of Biological Chemistry. 271: 21005-1011. PMID 8702863 DOI: 10.1074/Jbc.271.35.21005  0.603
1996 Nanda A, Brumell JH, Nordström T, Kjeldsen L, Sengeløv H, Borregaard N, Rotstem OD, Grinstein S. Activation of proton pumping in human neutrophils occurs by exocytosis of vesicles bearing vacuolar-type H+-ATPases Journal of Biological Chemistry. 271: 15963-15970. PMID 8663143 DOI: 10.1074/Jbc.271.27.15963  0.641
1996 Cabado AG, Yu FH, Kapus A, Lukacs G, Grinstein S, Orlowski J. Distinct structural domains confer cAMP sensitivity and ATP dependence to the Na+/H+ exchanger NHE3 isoform. The Journal of Biological Chemistry. 271: 3590-9. PMID 8631966 DOI: 10.1074/Jbc.271.7.3590  0.623
1996 Fukushima T, Waddell TK, Grinstein S, Goss GG, Orlowski J, Downey GP. Na+/H+ exchange activity during phagocytosis in human neutrophils: role of Fcgamma receptors and tyrosine kinases. The Journal of Cell Biology. 132: 1037-52. PMID 8601583 DOI: 10.1083/Jcb.132.6.1037  0.405
1996 Brumell JH, Burkhardt AL, Bolen JB, Grinstein S. Endogenous reactive oxygen intermediates activate tyrosine kinases in human neutrophils Journal of Biological Chemistry. 271: 1455-1461. PMID 8576138 DOI: 10.1074/Jbc.271.3.1455  0.6
1996 Brisseau GF, Grinstein S, Hackam DJ, Nordström T, Manolson MF, Khine AA, Rotstein OD. Interleukin-1 increases vacuolar-type H +-ATPase activity in murine peritoneal macrophages Journal of Biological Chemistry. 271: 2005-2011. PMID 8567651 DOI: 10.1074/Jbc.271.4.2005  0.557
1996 Goss G, Grinstein S. Chapter 7 Mechanisms of intracellular pH regulation Principles of Medical Biology. 4: 221-241. DOI: 10.1016/S1569-2582(96)80094-8  0.351
1995 Chow CW, Demaurex N, Grinstein S. Ion transport and the function of phagocytic cells. Current Opinion in Hematology. 2: 89-95. PMID 9371976 DOI: 10.1097/00062752-199502010-00012  0.368
1995 Downey GP, Grinstein S, Sue-A-Quan A, Czaban B, Chan CK. Volume regulation in leukocytes: requirement for an intact cytoskeleton. Journal of Cellular Physiology. 163: 96-104. PMID 7896904 DOI: 10.1002/Jcp.1041630111  0.351
1995 Nordström T, Rotstein OD, Romanek R, Asotra S, Heersche JN, Manolson MF, Brisseau GF, Grinstein S. Regulation of cytoplasmic pH in osteoclasts. Contribution of proton pumps and a proton-selective conductance. The Journal of Biological Chemistry. 270: 2203-12. PMID 7836451 DOI: 10.1074/Jbc.270.5.2203  0.588
1995 Brumell JH, Grinstein S. Serine/threonine kinase activation in human neutrophils: relationship to tyrosine phosphorylation. The American Journal of Physiology. 267: C1574-81. PMID 7810598 DOI: 10.1152/ajpcell.1994.267.6.C1574  0.521
1995 Nanda A, Grinstein S. Chemoattractant-induced activation of vacuolar H+ pumps and of an H(+)-selective conductance in neutrophils. Journal of Cellular Physiology. 165: 588-99. PMID 7593238 DOI: 10.1002/Jcp.1041650317  0.398
1994 Swallow CJ, Grinstein S, Sudsbury RA, Rotstein OD. Relative roles of Na+/H+ exchange and vacuolar-type H+ ATPases in regulating cytoplasmic pH and function in murine peritoneal macrophages. Journal of Cellular Physiology. 157: 453-60. PMID 8253856 DOI: 10.1002/Jcp.1041570304  0.566
1994 Nanda A, Curnutte JT, Grinstein S. Activation of H+ conductance in neutrophils requires assembly of components of the respiratory burst oxidase but not its redox function. The Journal of Clinical Investigation. 93: 1770-5. PMID 8163676 DOI: 10.1172/Jci117162  0.319
1994 Nordström T, Grinstein S, Brisseau GF, Manolson MF, Rotstein OD. Protein kinase C activation accelerates proton extrusion by vacuolar-type H(+)-ATPases in murine peritoneal macrophages. Febs Letters. 350: 82-6. PMID 8062929 DOI: 10.1016/0014-5793(94)00738-1  0.585
1994 Bianchini L, Nanda A, Wasan S, Grinstein S. Activation of multiple pH-regulatory pathways in granulocytes by a phosphotyrosine phosphatase antagonist. The Biochemical Journal. 539-44. PMID 8043000 DOI: 10.1042/Bj3010539  0.383
1994 Grinstein S, Woodside M, Goss GG, Kapus A. Osmotic activation of the Na+/H+ antiporter during volume regulation. Biochemical Society Transactions. 22: 512-6. PMID 7958357 DOI: 10.1042/Bst0220512  0.576
1994 Grinstein S, Romanek R, Rotstein OD. Method for manipulation of cytosolic pH in cells clamped in the whole cell or perforated-patch configurations. The American Journal of Physiology. 267: C1152-9. PMID 7943279 DOI: 10.1152/Ajpcell.1994.267.4.C1152  0.546
1993 Arellano R, Grinstein S. Role of isoprenylation in intracellular pH regulation of granulocytes. Febs Letters. 332: 247-50. PMID 8405466 DOI: 10.1016/0014-5793(93)80642-8  0.425
1993 Lukacs GL, Kapus A, Nanda A, Romanek R, Grinstein S. Proton conductance of the plasma membrane: properties, regulation, and functional role. The American Journal of Physiology. 265: C3-14. PMID 8393283 DOI: 10.1152/Ajpcell.1993.265.1.C3  0.628
1993 Downey GP, Takai A, Zamel R, Grinstein S, Chan CK. Okadaic acid-induced actin assembly in neutrophils: role of protein phosphatases. Journal of Cellular Physiology. 155: 505-19. PMID 8388002 DOI: 10.1002/Jcp.1041550309  0.373
1993 Kapus A, Romanek R, Qu AY, Rotstein OD, Grinstein S. A pH-sensitive and voltage-dependent proton conductance in the plasma membrane of macrophages Journal of General Physiology. 102: 729-760. PMID 8270911 DOI: 10.1085/Jgp.102.4.729  0.695
1993 Romanek R, Sargeant R, Paquet MR, Gluck S, Klip A, Grinstein S. Chloroquine inhibits glucose-transporter recruitment induced by insulin in rat adipocytes independently of its action on endomembrane pH. The Biochemical Journal. 296: 321-7. PMID 8257419 DOI: 10.1042/Bj2960321  0.643
1993 Dho S, Grinstein S, Foskett JK. Plasma membrane recycling in CFTR-expressing CHO cells. Biochimica Et Biophysica Acta. 1225: 78-82. PMID 7694659 DOI: 10.1016/0925-4439(93)90125-K  0.37
1993 Grinstein S, Woodside M, Waddell T, Downey G, Orlowski J, Pouyssegur J, Wong D, Foskett J. Focal localization of the NHE-1 isoform of the Na+/H+ antiport: assessment of effects on intracellular pH. The Embo Journal. 12: 5209-5218. DOI: 10.1002/J.1460-2075.1993.Tb06216.X  0.403
1992 Nanda A, Grinstein S. Protein kinase C activates an H+ (equivalent) conductance in the plasma membrane of human neutrophils. Proceedings of the National Academy of Sciences of the United States of America. 88: 10816-20. PMID 1720552 DOI: 10.1073/Pnas.88.23.10816  0.382
1992 Grinstein S, Furuya W, Downey GP. Activation of permeabilized neutrophils: role of anions. The American Journal of Physiology. 263: C78-85. PMID 1636684 DOI: 10.1152/Ajpcell.1992.263.1.C78  0.41
1992 Downey GP, Chan CK, Lea P, Takai A, Grinstein S. Phorbol ester-induced actin assembly in neutrophils: role of protein kinase C. The Journal of Cell Biology. 116: 695-706. PMID 1370499 DOI: 10.1083/Jcb.116.3.695  0.385
1992 Lu DJ, Takai A, Leto TL, Grinstein S. Modulation of neutrophil activation by okadaic acid, a protein phosphatase inhibitor. The American Journal of Physiology. 262: C39-49. PMID 1310215 DOI: 10.1152/Ajpcell.1992.262.1.C39  0.357
1992 Grinstein S, Furuya W, Bianchini L. Protein Kinases, Phosphatases, and the Control of Cell Volume Physiology. 7: 232-237. DOI: 10.1152/Physiologyonline.1992.7.5.232  0.312
1991 Trudel S, Pâquet MR, Grinstein S. Mechanism of vanadate-induced activation of tyrosine phosphorylation and of the respiratory burst in HL60 cells. Role of reduced oxygen metabolites. The Biochemical Journal. 276: 611-9. PMID 1712198 DOI: 10.1042/Bj2760611  0.336
1991 Swallow CJ, Grinstein S, Sudsbury RA, Rotstein OD. Nitric oxide derived from L-arginine impairs cytoplasmic pH regulation by vacuolar-type H+ ATPases in peritoneal macrophages. The Journal of Experimental Medicine. 174: 1009-21. PMID 1658185 DOI: 10.1084/jem.174.5.1009  0.455
1991 Lukacs GL, Nanda A, Rotstein OD, Grinstein S. The chloride channel blocker 5-nitro-2-(3-phenylpropyl-amino) benzoic acid (NPPB) uncouples mitochondria and increases the proton permeability of the plasma membrane in phagocytic cells. Febs Letters. 288: 17-20. PMID 1652470 DOI: 10.1016/0014-5793(91)80992-C  0.57
1991 Grinstein S, Swallow CJ, Rotstein OD. Regulation of cytoplasmic pH in phagocytic cell function and dysfunction. Clinical Biochemistry. 24: 241-7. PMID 1651820 DOI: 10.1016/0009-9120(91)80014-T  0.597
1991 Nanda A, Grinstein S. The Membrane Potential of Resting and Activated Neutrophils: Determinants and Significance Cellular Physiology and Biochemistry. 1: 65-75. DOI: 10.1159/000154595  0.395
1990 Swallow CJ, Grinstein S, Rotstein OD. Regulation of cytoplasmic pH in resident and activated peritoneal macrophages. Biochimica Et Biophysica Acta. 1022: 203-10. PMID 2155021 DOI: 10.1016/0005-2736(90)90115-5  0.577
1990 Mason MJ, Grinstein S. Effect of cytoplasmic acidification on the membrane potential of T-lymphocytes: role of trace metals. The Journal of Membrane Biology. 116: 139-48. PMID 2116524 DOI: 10.1007/Bf01868672  0.321
1990 Trudel S, Downey GP, Grinstein S, Pâquet MR. Activation of permeabilized HL60 cells by vanadate. Evidence for divergent signalling pathways. The Biochemical Journal. 269: 127-31. PMID 1695841 DOI: 10.1042/Bj2690127  0.369
1990 Swallow CJ, Grinstein S, Rotstein OD. Chapter 10 Regulation and Functional Significance of Cytoplasmic pH in Phagocytic Leukocytes Current Topics in Membranes and Transport. 35: 227-247. DOI: 10.1016/S0070-2161(08)60082-9  0.354
1989 Nasmith PE, Mills GB, Grinstein S. Guanine nucleotides induce tyrosine phosphorylation and activation of the respiratory burst in neutrophils. The Biochemical Journal. 257: 893-7. PMID 2930492 DOI: 10.1042/Bj2570893  0.319
1989 Downey GP, Grinstein S. Receptor-mediated actin assembly in electropermeabilized neutrophils: role of intracellular pH. Biochemical and Biophysical Research Communications. 160: 18-24. PMID 2712829 DOI: 10.1016/0006-291X(89)91614-8  0.374
1989 Rotin D, Grinstein S. Impaired cell volume regulation in Na+-H+ exchange-deficient mutants American Journal of Physiology - Cell Physiology. 257. PMID 2558570 DOI: 10.1152/ajpcell.1989.257.6.C1158  0.552
1989 Grinstein S, Hill M, Furuya W. Activation of electropermeabilized neutrophils by adenosine 5'-[gamma-thio]triphosphate (ATP[S]). Role of phosphatases in stimulus-response coupling. The Biochemical Journal. 261: 755-9. PMID 2552991 DOI: 10.1042/Bj2610755  0.348
1989 Swallow CJ, Rotstein OD, Grinstein S. Mechanisms of cytoplasmic pH recovery in acid-loaded macrophages. The Journal of Surgical Research. 46: 588-92. PMID 2543868 DOI: 10.1016/0022-4804(89)90025-5  0.574
1989 Mason MJ, Smith JD, Garcia-Soto JJ, Grinstein S. Internal pH-sensitive site couples Cl-(-)HCO3- exchange to Na+-H+ antiport in lymphocytes. The American Journal of Physiology. 256: C428-33. PMID 2537575 DOI: 10.1152/Ajpcell.1989.256.2.C428  0.355
1989 Rotstein OD, Vittorini T, Kao J, McBurney MI, Nasmith PE, Grinstein S. A soluble Bacteroides by-product impairs phagocytic killing of Escherichia coli by neutrophils. Infection and Immunity. 57: 745-53. PMID 2537256 DOI: 10.1128/Iai.57.3.745-753.1989  0.527
1989 Grinstein S, Rotin D, Mason MJ. Na+/H+ exchange and growth factor-induced cytosolic pH changes. Role in cellular proliferation Bba - Reviews On Biomembranes. 988: 73-97. PMID 2535787 DOI: 10.1016/0304-4157(89)90004-X  0.587
1989 Downey GP, Chan CK, Grinstein S. Actin assembly in electropermeabilized neutrophils: role of G-proteins. Biochemical and Biophysical Research Communications. 164: 700-5. PMID 2510721 DOI: 10.1016/0006-291X(89)91516-7  0.345
1989 Lu DJ, Grinstein S. Concanavalin A stimulation of O2 consumption in electropermeabilized neutrophils via a pertussis toxin-insensitive G protein. Febs Letters. 253: 151-6. PMID 2503397 DOI: 10.1016/0014-5793(89)80949-4  0.314
1989 Grinstein S, Smith JD, Benedict SH, Gelfand EW. Chapter 16 Activation of Sodium—Hydrogen Exchange by Mitogens Current Topics in Membranes and Transport. 34: 331-343. DOI: 10.1016/S0070-2161(08)60020-9  0.41
1988 Grinstein S. The Ayerst award lecture 1987/La Conférence Ayerst 1987. The intracellular pH of white blood cells: measurement and regulation. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 66: 245-9. PMID 3401375 DOI: 10.1139/O88-032  0.362
1988 Grinstein S, Furuya W, Nasmith PE, Rotstein OD. Na+/H+ exchange and the regulation of intracellular pH in polymorphonuclear leukocytes. Comparative Biochemistry and Physiology. a, Comparative Physiology. 90: 543-9. PMID 2902959 DOI: 10.1016/0300-9629(88)90665-2  0.587
1988 Mills GB, Girard P, Grinstein S, Gelfand EW. Interleukin-2 induces proliferation of T lymphocyte mutants lacking protein kinase C. Cell. 55: 91-100. PMID 2844411 DOI: 10.1016/0092-8674(88)90012-8  0.318
1988 Nasmith PE, Grinstein S. Cytosolic calcium, oxygen consumption and the intracellular pH of stimulated neutrophils. Bioscience Reports. 8: 65-76. PMID 2840131 DOI: 10.1007/Bf01128973  0.346
1987 Dixon SJ, Stewart D, Grinstein S, Spiegel S. Transmembrane signaling by the B subunit of cholera toxin: increased cytoplasmic free calcium in rat lymphocytes. The Journal of Cell Biology. 105: 1153-61. PMID 3654749 DOI: 10.1083/Jcb.105.3.1153  0.335
1987 Jakubovicz DE, Grinstein S, Klip A. Cell swelling following recovery from acidification in C6 glioma cells: an in vitro model of postischemic brain edema Brain Research. 435: 138-146. PMID 3427448 DOI: 10.1016/0006-8993(87)91594-0  0.649
1987 Rotstein OD, Houston K, Grinstein S. Control of cytoplasmic pH by Na+/H+ exchange in rat peritoneal macrophages activated with phorbol ester. Febs Letters. 215: 223-7. PMID 3034665 DOI: 10.1016/0014-5793(87)80150-3  0.572
1987 Rotstein OD, Nasmith PE, Grinstein S. The Bacteroides by-product succinic acid inhibits neutrophil respiratory burst by reducing intracellular pH. Infection and Immunity. 55: 864-70. PMID 3030935 DOI: 10.1128/Iai.55.4.864-870.1987  0.536
1987 Grinstein S, Furuya W. Cytoplasmic pH regulation in activated human neutrophils: effects of adenosine and pertussis toxin on Na+/H+ exchange and metabolic acidification. Biochimica Et Biophysica Acta. 889: 301-9. PMID 3024727 DOI: 10.1016/0167-4889(86)90192-8  0.398
1987 van der Meulen J, Klip A, Grinstein S. POSSIBLE MECHANISM FOR CEREBRAL OEDEMA IN DIABETIC KETOACIDOSIS The Lancet. 330: 306-308. PMID 2886767 DOI: 10.1016/S0140-6736(87)90892-0  0.651
1987 Livne A, Grinstein S, Rothstein A. Volume-regulating behavior of human platelets. Journal of Cellular Physiology. 131: 354-63. PMID 2439517 DOI: 10.1002/Jcp.1041310307  0.333
1987 Gelfand EW, Mills GB, Cheung RK, Lee JW, Grinstein S. Transmembrane ion fluxes during activation of human T lymphocytes: role of Ca2+, Na+/H+ exchange and phospholipid turnover. Immunological Reviews. 95: 59-87. PMID 2437015 DOI: 10.1111/J.1600-065X.1987.Tb00500.X  0.339
1987 Livne A, Grinstein S, Rothstein A. Characterization of Na+/H+ Exchange in Platelets Thrombosis and Haemostasis. 58: 971-977. DOI: 10.1055/S-0038-1646039  0.338
1986 Grinstein S, Furuya W, Cragoe EJ. Volume changes in activated human neutrophils: the role of Na+/H+ exchange. Journal of Cellular Physiology. 128: 33-40. PMID 3013905 DOI: 10.1002/Jcp.1041280107  0.355
1986 Nasmith PE, Grinstein S. Impairment of Na+/H+ exchange underlies inhibitory effects of Na+-free media on leukocyte function. Febs Letters. 202: 79-85. PMID 3013683 DOI: 10.1016/0014-5793(86)80653-6  0.343
1986 Klip A, Mack E, Cragoe EJ, Grinstein S. Regulation of amino acid uptake by phorbol esters and hypertonic solutions in rat thymocytes Journal of Cellular Physiology. 127: 244-252. PMID 3009498 DOI: 10.1002/Jcp.1041270209  0.626
1986 Grinstein S, Mack E, Mills GB. Osmotic activation of the Na+/H+ antiport in protein kinase C-depleted lymphocytes. Biochemical and Biophysical Research Communications. 134: 8-13. PMID 3004445 DOI: 10.1016/0006-291X(86)90519-X  0.337
1985 Grinstein S, Goetz JD, Rothstein A. 22Na+ fluxes in thymic lymphocytes. II. Amiloride-sensitive Na+/H+ exchange pathway; reversibility of transport and asymmetry of the modifier site. The Journal of General Physiology. 84: 585-600. PMID 6334130 DOI: 10.1085/Jgp.84.4.585  0.333
1985 Grinstein S, Goetz JD, Rothstein A. 22Na+ fluxes in thymic lymphocytes. I. Na+/Na+ and Na+/H+ exchange through an amiloride-insensitive pathway. The Journal of General Physiology. 84: 565-84. PMID 6334129 DOI: 10.1085/Jgp.84.4.565  0.311
1985 Gelfand EW, Cheung RK, Mills GB, Grinstein S. Mitogens trigger a calcium-independent signal for proliferation in phorbol-ester-treated lymphocytes. Nature. 315: 419-20. PMID 3923369 DOI: 10.1038/315419A0  0.321
1985 Grinstein S, Goetz JD. Control of free cytoplasmic calcium by intracellular pH in rat lymphocytes. Biochimica Et Biophysica Acta. 819: 267-70. PMID 2994735 DOI: 10.1016/0005-2736(85)90183-X  0.301
1985 Grinstein S, Cohen S, Goetz JD, Rothstein A. Osmotic and phorbol ester-induced activation of Na+/H+ exchange: possible role of protein phosphorylation in lymphocyte volume regulation. The Journal of Cell Biology. 101: 269-76. PMID 2989300 DOI: 10.1083/Jcb.101.1.269  0.386
1985 Grinstein S, Rothstein A, Cohen S. Mechanism of osmotic activation of Na+/H+ exchange in rat thymic lymphocytes. The Journal of General Physiology. 85: 765-87. PMID 2987392 DOI: 10.1085/Jgp.85.5.765  0.362
1985 Grinstein S, Cohen S, Goetz JD, Rothstein A, Gelfand EW. Characterization of the activation of Na+/H+ exchange in lymphocytes by phorbol esters: change in cytoplasmic pH dependence of the antiport. Proceedings of the National Academy of Sciences of the United States of America. 82: 1429-33. PMID 2983345 DOI: 10.1073/Pnas.82.5.1429  0.366
1985 Grinstein S, Cohen S, Rothstein A. Chemical modification of the Na+/H+ exchanger of thymic lymphocytes. Inhibition by N-ethylmaleimide. Biochimica Et Biophysica Acta. 812: 213-22. PMID 2981544 DOI: 10.1016/0005-2736(85)90541-3  0.343
1985 Sarkadi B, Cheung R, Mack E, Grinstein S, Gelfand EW, Rothstein A. Cation and anion transport pathways in volume regulatory response of human lymphocytes to hyposmotic media. The American Journal of Physiology. 248: C480-7. PMID 2581453 DOI: 10.1152/Ajpcell.1985.248.5.C480  0.341
1985 Grinstein S, Elder B, Furuya W. Phorbol ester-induced changes of cytoplasmic pH in neutrophils: role of exocytosis in Na+-H+ exchange. The American Journal of Physiology. 248: C379-86. PMID 2579574 DOI: 10.1152/Ajpcell.1985.248.3.C379  0.373
1984 Sarkadi B, Attisano L, Grinstein S, Buchwald M, Rothstein A. Volume regulation of Chinese hamster ovary cells in anisoosmotic media. Biochimica Et Biophysica Acta. 774: 159-68. PMID 6743652 DOI: 10.1016/0005-2736(84)90287-6  0.385
1984 Grinstein S, Furuya W. Intracellular distribution of acridine derivatives in platelets and their suitability for cytoplasmic pH measurements. Biochimica Et Biophysica Acta. 803: 221-8. PMID 6704433 DOI: 10.1016/0167-4889(84)90111-3  0.345
1984 Gelfand EW, Cheung RK, Grinstein S. Role of membrane potential in the regulation of lectin-induced calcium uptake. Journal of Cellular Physiology. 121: 533-9. PMID 6501431 DOI: 10.1002/Jcp.1041210312  0.353
1984 Grinstein S, Furuya W. Comparative study of the major glycoproteins of the plasma membrane and secretory granule membranes of porcine platelets. Comparative Biochemistry and Physiology. B, Comparative Biochemistry. 78: 657-62. PMID 6478798 DOI: 10.1016/0305-0491(84)90114-7  0.35
1984 Grinstein S, Rothstein A, Sarkadi B, Gelfand EW. Responses of lymphocytes to anisotonic media: volume-regulating behavior. The American Journal of Physiology. 246: C204-15. PMID 6367480 DOI: 10.1152/Ajpcell.1984.246.3.C204  0.341
1984 Grinstein S, Cohen S, Lederman HM, Gelfand EW. The intracellular pH of quiescent and proliferating human and rat thymic lymphocytes. Journal of Cellular Physiology. 121: 87-95. PMID 6332816 DOI: 10.1002/Jcp.1041210112  0.339
1984 Grinstein S, Cohen S, Rothstein A. Cytoplasmic pH regulation in thymic lymphocytes by an amiloride-sensitive Na+/H+ antiport. The Journal of General Physiology. 83: 341-69. PMID 6325586 DOI: 10.1085/Jgp.83.3.341  0.351
1984 Grinstein S, Goetz JD, Furuya W, Rothstein A, Gelfand EW. Amiloride-sensitive Na+-H+ exchange in platelets and leukocytes: detection by electronic cell sizing. The American Journal of Physiology. 247: C293-8. PMID 6089580 DOI: 10.1152/Ajpcell.1984.247.3.C293  0.359
1984 Grinstein S, Furuya W. Amiloride-sensitive Na+/H+ exchange in human neutrophils: mechanism of activation by chemotactic factors. Biochemical and Biophysical Research Communications. 122: 755-62. PMID 6087813 DOI: 10.1016/S0006-291X(84)80098-4  0.345
1983 Van der Meulen J, Furuya W, Grinstein S. Isolation and partial characterization of platelet alpha-granule membranes. The Journal of Membrane Biology. 71: 47-59. PMID 6834421 DOI: 10.1007/Bf01870674  0.332
1983 Grinstein S, Clarke CA, Rothstein A. Activation of Na+/H+ exchange in lymphocytes by osmotically induced volume changes and by cytoplasmic acidification Journal of General Physiology. 82: 619-638. PMID 6644271 DOI: 10.1085/Jgp.82.5.619  0.345
1983 Grinstein S, Cohen S, Sarkadi B, Rothstein A. Induction of 86Rb fluxes by Ca2+ and volume changes in thymocytes and their isolated membranes. Journal of Cellular Physiology. 116: 352-62. PMID 6604061 DOI: 10.1002/Jcp.1041160313  0.353
1983 Grinstein S, Cohen S. Measurement of sidedness of isolated plasma-membrane vesicles: quantitation of actin exposure by DNase I inactivation. Analytical Biochemistry. 130: 151-7. PMID 6223539 DOI: 10.1016/0003-2697(83)90662-0  0.38
1983 Grinstein S, Clarke CA, Rothstein A, Gelfand EW. Volume-induced anion conductance in human B lymphocytes is cation independent The American Journal of Physiology. 245. PMID 6191575 DOI: 10.1152/Ajpcell.1983.245.1.C160  0.346
1983 Grinstein S, Furuya W. A Mg2+-stimulated ATPase in platelet alpha-granule membranes: possible involvement in proton translocation. Archives of Biochemistry and Biophysics. 218: 502-12. PMID 6130746 DOI: 10.1016/0003-9861(82)90374-5  0.341
1982 Grinstein S, Clarke CA, Dupre A, Rothstein A. Volume-induced increase of anion permeability in human lymphocytes Journal of General Physiology. 80: 801-823. PMID 7175489 DOI: 10.1085/Jgp.80.6.801  0.322
1982 Grinstein S, Furuya W. Calmodulin binding to platelet plasma membranes. Biochimica Et Biophysica Acta. 686: 55-64. PMID 7066322 DOI: 10.1016/0005-2736(82)90151-1  0.323
1982 Cheung RK, Grinstein S, Dosch HM, Gelfand EW. Volume regulation by human lymphocytes: characterization of the ionic basis for regulatory volume decrease. Journal of Cellular Physiology. 112: 189-96. PMID 6288741 DOI: 10.1002/Jcp.1041120206  0.313
1982 Grinstein S, Clarke CA, Rothstein A. Increased anion permeability during volume regulation in human lymphocytes Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. 299: 509-518. PMID 6130543 DOI: 10.1098/Rstb.1982.0148  0.316
1982 Grinstein S, Vander Meulen J, Furuya W. Possible role of H+ -alkali cation countertransport in secretary granule swelling during exocytosis Febs Letters. 148: 1-4. DOI: 10.1016/0014-5793(82)81230-1  0.367
1981 van der Meulen JA, Emerson DM, Grinstein S. Isolation of chromaffin cell plasma membranes on polycationic beads. Biochimica Et Biophysica Acta. 643: 601-15. PMID 7248289 DOI: 10.1016/0005-2736(81)90356-4  0.387
1981 Ramjeesingh M, Grinstein S, Rothstein A. Intrinsic segments of band 3 that are associated with anion transport across red blood cell membranes. The Journal of Membrane Biology. 57: 95-102. PMID 7205945 DOI: 10.1007/Bf01868996  0.335
1980 Klip A, Grinstein S, Semenza G. The small-intestinal sodium, D-glucose cotransporter is inserted in the brush border membrane asymmetrically Annals of the New York Academy of Sciences. 358: 374-377. PMID 6938160 DOI: 10.1111/J.1749-6632.1980.Tb15426.X  0.714
1980 Klip A, Grinstein S, Biber J, Semenza G. Interaction of the sugar carrier of intestinal brush-border membranes with HgCl2 Bba - Biomembranes. 598: 100-114. PMID 6448071 DOI: 10.1016/0005-2736(80)90268-0  0.734
1979 Klip A, Grinstein S, Semenza G. Partial purification of the sugar carrier of intestinal brush border membranes. Enrichment of the phlorizin-binding component by selective extractions The Journal of Membrane Biology. 51: 47-73. PMID 522129 DOI: 10.1007/Bf01869343  0.731
1979 Klip A, Grinstein S, Semenza G. Distribution of sulfhydryl groups in intestinal brush border membranes. Localization of side-chains essential for glucose transport and phlorizin binding Bba - Biomembranes. 558: 233-245. PMID 508745 DOI: 10.1016/0005-2736(79)90063-4  0.748
1979 Klip A, Grinstein S, Semenza G. Transmembrane disposition of the phlorizin binding protein of intestinal brush borders Febs Letters. 99: 91-96. PMID 437137 DOI: 10.1016/0014-5793(79)80256-2  0.695
1979 Klip A, Grinstein S, Marti T, Semenza G. Transient opening of brush border membrane vesicles in alkaline media. Preservation of D-glucose transport after removal of extrinsic proteins Febs Letters. 105: 224-228. PMID 39782 DOI: 10.1016/0014-5793(79)80616-X  0.727
1978 Grinstein S, Ship S, Rothstein A. Anion transport in relation to proteolytic dissection of band 3 protein. Biochimica Et Biophysica Acta. 507: 294-304. PMID 626736 DOI: 10.1016/0005-2736(78)90424-8  0.36
1978 Grinstein S, Rothstein A. Chemically-induced cation permeability in red cell membrane vesicles. The sidedness of the response and the proteins involved. Biochimica Et Biophysica Acta. 508: 236-45. PMID 205244 DOI: 10.1016/0005-2736(78)90327-9  0.388
1977 Grinstein S, Erlij D. Differences between resting and insulin-stimulated amino acid transport in frog skeletal muscle. The Journal of Membrane Biology. 35: 9-28. PMID 196085 DOI: 10.1007/Bf01869937  0.305
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