| Year |
Citation |
Score |
| 2017 |
Tsang AT, Dudgeon C, Yi L, Yu X, Goraczniak R, Donohue K, Kogan S, Brenneman MA, Ho ES, Gunderson SI, Carpizo DR. U1 Adaptors suppress the KRAS-MYC oncogenic axis in human pancreatic cancer xenografts. Molecular Cancer Therapeutics. PMID 28377488 DOI: 10.1158/1535-7163.Mct-16-0867 |
0.64 |
|
| 2016 |
Boregowda RK, Medina DJ, Markert E, Bryan MA, Chen W, Chen S, Rabkin A, Vido MJ, Gunderson SI, Chekmareva M, Foran DJ, Lasfar A, Goydos JS, Cohen-Solal KA. The transcription factor RUNX2 regulates receptor tyrosine kinase expression in melanoma. Oncotarget. PMID 27102439 DOI: 10.18632/Oncotarget.8822 |
0.314 |
|
| 2016 |
Carpizo D, Tsang A, Yu X, Yi L, Dudgeon C, Donohue K, Brenneman M, Goraczniak R, Gunderson S. 262. Therapeutic Suppression of the KRAS-MYC Oncogenic Axis in Human Pancreatic Cancer Xenografts with U1 Adaptor Oligonucleotide / RGD Peptide Conjugates Molecular Therapy. 24: S104. DOI: 10.1016/S1525-0016(16)33071-4 |
0.459 |
|
| 2016 |
Richfield E, Prasad K, Brenneman M, Goraczniak R, Gunderson S. 259. Targeted Gene Silencing by U1 Adaptor Oligonucleotides in Preclinical Models of Parkinson's Disease and Huntington's Disease Molecular Therapy. 24: S102. DOI: 10.1016/S1525-0016(16)33068-4 |
0.523 |
|
| 2015 |
Li W, You B, Hoque M, Zheng D, Luo W, Ji Z, Park JY, Gunderson SI, Kalsotra A, Manley JL, Tian B. Systematic profiling of poly(A)+ transcripts modulated by core 3' end processing and splicing factors reveals regulatory rules of alternative cleavage and polyadenylation. Plos Genetics. 11: e1005166. PMID 25906188 DOI: 10.1371/Journal.Pgen.1005166 |
0.478 |
|
| 2015 |
Tsang AT, Yu X, Goraczniak R, Brenneman M, Gunderson S, Carpizo DR. 694. Targeting KRAS in Pancreatic Cancer by Gene Silencing with U1 Adaptors Molecular Therapy. 23: S276-S277. DOI: 10.1016/S1525-0016(16)34303-9 |
0.467 |
|
| 2014 |
Tsang AT, Yu X, Goraczniak R, Brenneman M, Gunderson S, Carpizo DR. Abstract B52: Therapeutic targeting of human KRAS in pancreatic cancer using a novel method of gene-silencing: U1 adaptors Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Rasonc14-B52 |
0.518 |
|
| 2013 |
Luo W, Ji Z, Pan Z, You B, Hoque M, Li W, Gunderson SI, Tian B. The conserved intronic cleavage and polyadenylation site of CstF-77 gene imparts control of 3' end processing activity through feedback autoregulation and by U1 snRNP. Plos Genetics. 9: e1003613. PMID 23874216 DOI: 10.1371/Journal.Pgen.1003613 |
0.471 |
|
| 2013 |
Goraczniak R, Wall BA, Behlke MA, Lennox KA, Ho ES, Zaphiros NH, Jakubowski C, Patel NR, Zhao S, Magaway C, Subbie SA, Jenny Yu L, Lacava S, Reuhl KR, Chen S, ... Gunderson SI, et al. U1 Adaptor Oligonucleotides Targeting BCL2 and GRM1 Suppress Growth of Human Melanoma Xenografts In Vivo. Molecular Therapy. Nucleic Acids. 2: e92. PMID 23673539 DOI: 10.1038/Mtna.2013.24 |
0.67 |
|
| 2013 |
Ho ES, Gunderson SI, Duffy S. A multispecies polyadenylation site model. Bmc Bioinformatics. 14: S9. PMID 23368518 DOI: 10.1186/1471-2105-14-S2-S9 |
0.674 |
|
| 2011 |
Ho ES, Gunderson SI. Long conserved fragments upstream of Mammalian polyadenylation sites. Genome Biology and Evolution. 3: 654-66. PMID 21705472 DOI: 10.1093/Gbe/Evr053 |
0.692 |
|
| 2009 |
Ho ES, Jakubowski CD, Gunderson SI. iTriplet, a rule-based nucleic acid sequence motif finder. Algorithms For Molecular Biology : Amb. 4: 14. PMID 19874606 DOI: 10.1186/1748-7188-4-14 |
0.584 |
|
| 2009 |
Reid DC, Chang BL, Gunderson SI, Alpert L, Thompson WA, Fairbrother WG. Next-generation SELEX identifies sequence and structural determinants of splicing factor binding in human pre-mRNA sequence. Rna (New York, N.Y.). 15: 2385-97. PMID 19861426 DOI: 10.1261/Rna.1821809 |
0.502 |
|
| 2009 |
Wypijewski K, Hornyik C, Shaw JA, Stephens J, Goraczniak R, Gunderson SI, Lacomme C. Ectopic 5' splice sites inhibit gene expression by engaging RNA surveillance and silencing pathways in plants. Plant Physiology. 151: 955-65. PMID 19666706 DOI: 10.1104/Pp.109.139733 |
0.514 |
|
| 2009 |
Li Y, Ho ES, Gunderson SI, Kiledjian M. Mutational analysis of a Dcp2-binding element reveals general enhancement of decapping by 5'-end stem-loop structures. Nucleic Acids Research. 37: 2227-37. PMID 19233875 DOI: 10.1093/Nar/Gkp087 |
0.685 |
|
| 2009 |
Goraczniak R, Behlke MA, Gunderson SI. Gene silencing by synthetic U1 adaptors. Nature Biotechnology. 27: 257-63. PMID 19219028 DOI: 10.1038/Nbt.1525 |
0.557 |
|
| 2008 |
Jankowska A, Gunderson SI, Andrusiewicz M, Burczynska B, Szczerba A, Jarmolowski A, Nowak-Markwitz E, Warchol JB. Reduction of human chorionic gonadotropin beta subunit expression by modified U1 snRNA caused apoptosis in cervical cancer cells. Molecular Cancer. 7: 26. PMID 18339208 DOI: 10.1186/1476-4598-7-26 |
0.493 |
|
| 2008 |
Abad X, Vera M, Jung SP, Oswald E, Romero I, Amin V, Fortes P, Gunderson SI. Requirements for gene silencing mediated by U1 snRNA binding to a target sequence. Nucleic Acids Research. 36: 2338-52. PMID 18299285 DOI: 10.1093/Nar/Gkn068 |
0.569 |
|
| 2008 |
Goraczniak R, Gunderson SI. The regulatory element in the 3'-untranslated region of human papillomavirus 16 inhibits expression by binding CUG-binding protein 1. The Journal of Biological Chemistry. 283: 2286-96. PMID 18042543 DOI: 10.1074/Jbc.M708789200 |
0.548 |
|
| 2007 |
Guan F, Caratozzolo RM, Goraczniak R, Ho ES, Gunderson SI. A bipartite U1 site represses U1A expression by synergizing with PIE to inhibit nuclear polyadenylation. Rna (New York, N.Y.). 13: 2129-40. PMID 17942741 DOI: 10.1261/Rna.756707 |
0.563 |
|
| 2006 |
Ma J, Gunderson SI, Phillips C. Non-snRNP U1A levels decrease during mammalian B-cell differentiation and release the IgM secretory poly(A) site from repression. Rna (New York, N.Y.). 12: 122-32. PMID 16373497 DOI: 10.1261/Rna.2159506 |
0.635 |
|
| 2005 |
Lee JH, Cook JR, Yang ZH, Mirochnitchenko O, Gunderson SI, Felix AM, Herth N, Hoffmann R, Pestka S. PRMT7, a new protein arginine methyltransferase that synthesizes symmetric dimethylarginine. The Journal of Biological Chemistry. 280: 3656-64. PMID 15494416 DOI: 10.1074/Jbc.M405295200 |
0.307 |
|
| 2004 |
Phillips C, Pachikara N, Gunderson SI. U1A inhibits cleavage at the immunoglobulin M heavy-chain secretory poly(A) site by binding between the two downstream GU-rich regions. Molecular and Cellular Biology. 24: 6162-71. PMID 15226420 DOI: 10.1128/Mcb.24.14.6162-6171.2004 |
0.504 |
|
| 2004 |
Akum BF, Chen M, Gunderson SI, Riefler GM, Scerri-Hansen MM, Firestein BL. Cypin regulates dendrite patterning in hippocampal neurons by promoting microtubule assembly. Nature Neuroscience. 7: 145-52. PMID 14730308 DOI: 10.1038/Nn1179 |
0.374 |
|
| 2003 |
Fortes P, Cuevas Y, Guan F, Liu P, Pentlicky S, Jung SP, Martínez-Chantar ML, Prieto J, Rowe D, Gunderson SI. Inhibiting expression of specific genes in mammalian cells with 5' end-mutated U1 small nuclear RNAs targeted to terminal exons of pre-mRNA. Proceedings of the National Academy of Sciences of the United States of America. 100: 8264-9. PMID 12826613 DOI: 10.1073/Pnas.1332669100 |
0.719 |
|
| 2003 |
Guan F, Palacios D, Hussein RI, Gunderson SI. Determinants within an 18-amino-acid U1A autoregulatory domain that uncouple cooperative RNA binding, inhibition of polyadenylation, and homodimerization. Molecular and Cellular Biology. 23: 3163-72. PMID 12697817 DOI: 10.1128/Mcb.23.9.3163-3172.2003 |
0.657 |
|
| 2003 |
Phillips C, Gunderson S. Sequences adjacent to the 5' splice site control U1A binding upstream of the IgM heavy chain secretory poly(A) site. The Journal of Biological Chemistry. 278: 22102-11. PMID 12670951 DOI: 10.1074/Jbc.M301349200 |
0.532 |
|
| 2002 |
Ko B, Gunderson SI. Identification of new poly(A) polymerase-inhibitory proteins capable of regulating pre-mRNA polyadenylation. Journal of Molecular Biology. 318: 1189-206. PMID 12083511 DOI: 10.1016/S0022-2836(02)00240-1 |
0.498 |
|
| 2002 |
Phillips C, Jung S, Gunderson SI. Regulation of nuclear poly(A) addition controls the expression of immunoglobulin M secretory mRNA. The Embo Journal. 20: 6443-52. PMID 11707415 DOI: 10.1093/Emboj/20.22.6443 |
0.556 |
|
| 2001 |
Beckley SA, Liu P, Stover ML, Gunderson SI, Lichtler AC, Rowe DW. Reduction of target gene expression by a modified U1 snRNA Molecular and Cellular Biology. 21: 2815-2825. PMID 11283260 DOI: 10.1128/Mcb.21.8.2815-2825.2001 |
0.595 |
|
| 2000 |
Varani L, Gunderson SI, Mattaj IW, Kay LE, Neuhaus D, Varani G. The NMR structure of the 38 kDa U1A protein - PIE RNA complex reveals the basis of cooperativity in regulation of polyadenylation by human U1A protein. Nature Structural Biology. 7: 329-35. PMID 10742179 DOI: 10.1038/74101 |
0.482 |
|
| 2000 |
Klein Gunnewiek JM, Hussein RI, van Aarssen Y, Palacios D, de Jong R, van Venrooij WJ, Gunderson SI. Fourteen residues of the U1 snRNP-specific U1A protein are required for homodimerization, cooperative RNA binding, and inhibition of polyadenylation. Molecular and Cellular Biology. 20: 2209-17. PMID 10688667 DOI: 10.1128/Mcb.20.6.2209-2217.2000 |
0.465 |
|
| 2000 |
Vagner S, Rüegsegger U, Gunderson SI, Keller W, Mattaj IW. Position-dependent inhibition of the cleavage step of pre-mRNA 3'-end processing by U1 snRNP. Rna (New York, N.Y.). 6: 178-88. PMID 10688357 DOI: 10.1017/S1355838200991854 |
0.57 |
|
| 1998 |
Gunderson SI, Polycarpou-Schwarz M, Mattaj IW. U1 snRNP inhibits pre-mRNA polyadenylation through a direct interaction between U1 70K and poly(A) polymerase. Molecular Cell. 1: 255-64. PMID 9659922 DOI: 10.1016/S1097-2765(00)80026-X |
0.562 |
|
| 1997 |
Gunderson SI, Vagner S, Polycarpou-Schwarz M, Mattaj IW. Involvement of the carboxyl terminus of vertebrate poly(A) polymerase in U1A autoregulation and in the coupling of splicing and polyadenylation. Genes & Development. 11: 761-73. PMID 9087430 DOI: 10.1101/Gad.11.6.761 |
0.455 |
|
| 1996 |
Lewis JD, Gunderson SI, Mattaj IW. The influence of 5' and 3' end structures on pre-mRNA metabolism. Journal of Cell Science. Supplement. 19: 13-9. PMID 8655642 DOI: 10.1242/Jcs.1995.Supplement_19.2 |
0.474 |
|
| 1994 |
Gunderson SI, Beyer K, Martin G, Keller W, Boelens WC, Mattaj LW. The human U1A snRNP protein regulates polyadenylation via a direct interaction with poly(A) polymerase. Cell. 76: 531-41. PMID 8313473 DOI: 10.1016/0092-8674(94)90116-3 |
0.472 |
|
| 1993 |
Boelens WC, Jansen EJ, van Venrooij WJ, Stripecke R, Mattaj IW, Gunderson SI. The human U1 snRNP-specific U1A protein inhibits polyadenylation of its own pre-mRNA. Cell. 72: 881-92. PMID 8458082 DOI: 10.1016/0092-8674(93)90577-D |
0.542 |
|
| 1993 |
van Gelder C, Gunderson S, Jansen E, Boelens W, Polycarpou-Schwarz M, Mattaj I, van Venrooij W. A complex secondary structure in U1A pre-mRNA that binds two molecules of U1A protein is required for regulation of polyadenylation. The Embo Journal. 12: 5191-5200. DOI: 10.1002/j.1460-2075.1993.tb06214.x |
0.325 |
|
| 1993 |
Bernués J, Simmen K, Lewis J, Gunderson S, Polycarpou-Schwarz M, Moncollin V, Egly J, Mattaj I. Common and unique transcription factor requirements of human U1 and U6 snRNA genes. The Embo Journal. 12: 3573-3585. DOI: 10.1002/J.1460-2075.1993.Tb06031.X |
0.53 |
|
| 1990 |
Gunderson SI, Knuth MW, Burgess RR. The human U1 snRNA promoter correctly initiates transcription in vitro and is activated by PSE1 Genes and Development. 4: 2048-2060. PMID 2125285 DOI: 10.1101/Gad.4.12A.2048 |
0.518 |
|
| 1988 |
Chapman KA, Gunderson SI, Anello M, Wells RD, Burgess RR. Bacteriophage T7 late promoters with point mutations: Quantitative footprinting and in vivo expression Nucleic Acids Research. 16: 4511-4524. PMID 3288970 DOI: 10.1093/Nar/16.10.4511 |
0.305 |
|
| 1987 |
Gunderson SI, Chapman KA, Burgess RR. Interactions of T7 RNA polymerase with T7 late promoters measured by footprinting with methidiumpropyl-EDTA-iron(II) Biochemistry. 26: 1539-1546. PMID 3036203 DOI: 10.1021/Bi00380A007 |
0.369 |
|
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