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Dipali G. Sashital, Ph.D. - Publications

Affiliations: 
Biochemistry, Biophysics and Molecular Biology Iowa State University, Ames, IA, United States 
 2006 University of Wisconsin, Madison, Madison, WI 
Area:
RNA-protein interactions
Website:
https://www.bbmb.iastate.edu/people/dipali-sashital
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47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Nguyen GT, Schelling MA, Raju A, Buscher KA, Sritharan A, Sashital DG. CRISPR-Cas12a exhibits metal-dependent specificity switching. Nucleic Acids Research. PMID 39019776 DOI: 10.1093/nar/gkae613  0.794
2023 Nguyen GT, Schelling MA, Buscher KA, Sritharan A, Sashital DG. CRISPR-Cas12a exhibits metal-dependent specificity switching. Biorxiv : the Preprint Server For Biology. PMID 38076861 DOI: 10.1101/2023.11.29.569287  0.793
2023 Dhingra Y, Sashital DG. A tool for more specific DNA integration. Science (New York, N.Y.). 382: 768-769. PMID 37972178 DOI: 10.1126/science.adl0863  0.797
2023 Adler BA, Trinidad MI, Bellieny-Rabelo D, Zhang E, Karp HM, Skopintsev P, Thornton BW, Weissman RF, Yoon PH, Chen L, Hessler T, Eggers AR, Colognori D, Boger R, Doherty EE, ... ... Sashital DG, et al. CasPEDIA Database: a functional classification system for class 2 CRISPR-Cas enzymes. Nucleic Acids Research. PMID 37889041 DOI: 10.1093/nar/gkad890  0.786
2023 Dhingra Y, Sashital DG. Cas4/1 dual nuclease activities enable prespacer maturation and directional integration in a type I-G CRISPR-Cas system. The Journal of Biological Chemistry. 105178. PMID 37607619 DOI: 10.1016/j.jbc.2023.105178  0.831
2023 Dhingra Y, Sashital DG. Cas4/1 dual nuclease activities enable prespacer maturation and directional integration in a type I-G CRISPR-Cas system. Biorxiv : the Preprint Server For Biology. PMID 37333257 DOI: 10.1101/2023.06.05.543779  0.831
2023 Schelling MA, Nguyen GT, Sashital DG. CRISPR-Cas effector specificity and cleavage site determine phage escape outcomes. Plos Biology. 21: e3002065. PMID 37058530 DOI: 10.1371/journal.pbio.3002065  0.824
2022 Dhingra Y, Suresh SK, Juneja P, Sashital DG. PAM binding ensures orientational integration during Cas4-Cas1-Cas2-mediated CRISPR adaptation. Molecular Cell. PMID 36272411 DOI: 10.1016/j.molcel.2022.09.030  0.8
2022 Nguyen GT, Dhingra Y, Sashital DG. Miniature CRISPR-Cas12 endonucleases - Programmed DNA targeting in a smaller package. Current Opinion in Structural Biology. 77: 102466. PMID 36170778 DOI: 10.1016/j.sbi.2022.102466  0.826
2022 Lee H, Sashital DG. Creating memories: molecular mechanisms of CRISPR adaptation. Trends in Biochemical Sciences. PMID 35236570 DOI: 10.1016/j.tibs.2022.02.004  0.814
2021 Murugan K, Suresh SK, Seetharam AS, Severin AJ, Sashital DG. Systematic in vitro specificity profiling reveals nicking defects in natural and engineered CRISPR-Cas9 variants. Nucleic Acids Research. PMID 33744974 DOI: 10.1093/nar/gkab163  0.783
2020 Dhingra Y, Sashital DG. Updating the CRISPR Catalogue. The Crispr Journal. 3: 78-80. PMID 32315221 DOI: 10.1089/crispr.2020.29088.ydh  0.777
2020 Schelling MA, Sashital DG. An adaptable defense. Elife. 9. PMID 32223888 DOI: 10.7554/Elife.56122  0.766
2020 Murugan K, Seetharam AS, Severin AJ, Sashital DG. CRISPR-Cas12a has widespread off-target and dsDNA-nicking effects. The Journal of Biological Chemistry. PMID 32161115 DOI: 10.1074/Jbc.Ra120.012933  0.835
2020 Wade JT, Kranzusch PJ, Sashital DG. Decision letter: Tetramerisation of the CRISPR ring nuclease Crn3/Csx3 facilitates cyclic oligoadenylate cleavage Elife. DOI: 10.7554/Elife.57627.Sa1  0.58
2019 Banakar R, Eggenberger AL, Lee K, Wright DA, Murugan K, Zarecor S, Lawrence-Dill CJ, Sashital DG, Wang K. High-frequency random DNA insertions upon co-delivery of CRISPR-Cas9 ribonucleoprotein and selectable marker plasmid in rice. Scientific Reports. 9: 19902. PMID 31882637 DOI: 10.1038/S41598-019-55681-Y  0.801
2019 Lee H, Dhingra Y, Sashital DG. The Cas4-Cas1-Cas2 complex mediates precise prespacer processing during CRISPR adaptation. Elife. 8. PMID 31021314 DOI: 10.7554/Elife.44248  0.801
2019 Suresh SK, Murugan K, Sashital DG. Enzymatic anti-CRISPRs improve the bacteriophage arsenal. Nature Structural & Molecular Biology. 26: 250-251. PMID 30936525 DOI: 10.1038/S41594-019-0210-5  0.761
2019 Xue C, Sashital DG. Mechanisms of Type I-E and I-F CRISPR-Cas Systems in . Ecosal Plus. 8. PMID 30724156 DOI: 10.1128/ecosalplus.ESP-0008-2018  0.75
2019 Phan PT, Schelling M, Xue C, Sashital DG. Fluorescence-based methods for measuring target interference by CRISPR-Cas systems. Methods in Enzymology. 616: 61-85. PMID 30691655 DOI: 10.1016/Bs.Mie.2018.10.027  0.8
2019 Mekler V, Kuznedelov K, Minakhin L, Murugan K, Sashital DG, Severinov K. CRISPR-Cas molecular beacons as tool for studies of assembly of CRISPR-Cas effector complexes and their interactions with DNA. Methods in Enzymology. 616: 337-363. PMID 30691650 DOI: 10.1016/Bs.Mie.2018.10.026  0.828
2019 Lee H, Dhingra Y, Sashital DG. Author response: The Cas4-Cas1-Cas2 complex mediates precise prespacer processing during CRISPR adaptation Elife. DOI: 10.7554/Elife.44248.048  0.766
2018 Davis-Vogel C, Van Allen B, Van Hemert JL, Sethi A, Nelson ME, Sashital DG. Identification and comparison of key RNA interference machinery from western corn rootworm, fall armyworm, and southern green stink bug. Plos One. 13: e0203160. PMID 30183751 DOI: 10.1371/Journal.Pone.0203160  0.781
2018 Davis-Vogel C, Ortiz A, Procyk L, Robeson J, Kassa A, Wang Y, Huang E, Walker C, Sethi A, Nelson ME, Sashital DG. Knockdown of RNA interference pathway genes impacts the fitness of western corn rootworm. Scientific Reports. 8: 7858. PMID 29777111 DOI: 10.1038/S41598-018-26129-6  0.77
2018 Sashital DG. Pathogen detection in the CRISPR-Cas era. Genome Medicine. 10: 32. PMID 29690921 DOI: 10.1186/S13073-018-0543-4  0.403
2018 Lee H, Zhou Y, Taylor DW, Sashital DG. Cas4-Dependent Prespacer Processing Ensures High-Fidelity Programming of CRISPR Arrays. Molecular Cell. PMID 29602742 DOI: 10.1016/J.Molcel.2018.03.003  0.826
2018 Mekler V, Minakhin L, Kuznedelov K, Murugan K, Sashital D, Severinov K. Duplex DNA Destabilization by Type V CRISPR-Cas Nucleases during Interrogation of DNA Biophysical Journal. 114: 250a. DOI: 10.1016/J.Bpj.2017.11.1390  0.8
2017 Xue C, Zhu Y, Zhang X, Shin YK, Sashital DG. Real-Time Observation of Target Search by the CRISPR Surveillance Complex Cascade. Cell Reports. 21: 3717-3727. PMID 29281822 DOI: 10.1016/J.Bpj.2017.11.1393  0.773
2017 Murugan K, Babu K, Sundaresan R, Rajan R, Sashital DG. The Revolution Continues: Newly Discovered Systems Expand the CRISPR-Cas Toolkit. Molecular Cell. 68: 15-25. PMID 28985502 DOI: 10.1016/J.Molcel.2017.09.007  0.812
2017 Sashital DG. Prokaryotic Argonaute Uses an All-in-One Mechanism to Provide Host Defense. Molecular Cell. 65: 957-958. PMID 28306508 DOI: 10.1016/J.Molcel.2017.03.002  0.353
2016 Wolt JD, Wang K, Sashital D, Lawrence-Dill CJ. Achieving Plant CRISPR Targeting that Limits Off-Target Effects. The Plant Genome. 9. PMID 27902801 DOI: 10.3835/Plantgenome2016.05.0047  0.371
2016 Xue C, Whitis NR, Sashital DG. Conformational Control of Cascade Interference and Priming Activities in CRISPR Immunity. Molecular Cell. 64: 826-834. PMID 27871367 DOI: 10.1016/J.Molcel.2016.09.033  0.756
2015 Xue C, Seetharam AS, Musharova O, Severinov K, Brouns SJ, Severin AJ, Sashital DG. CRISPR interference and priming varies with individual spacer sequences. Nucleic Acids Research. PMID 26586800 DOI: 10.1093/Nar/Gkv1259  0.775
2014 Sashital DG, Greeman CA, Lyumkis D, Potter CS, Carragher B, Williamson JR. A combined quantitative mass spectrometry and electron microscopy analysis of ribosomal 30S subunit assembly in E. coli. Elife. 3. PMID 25313868 DOI: 10.7554/Elife.04491  0.561
2012 Sashital DG, Wiedenheft B, Doudna JA. Mechanism of foreign DNA selection in a bacterial adaptive immune system. Molecular Cell. 46: 606-15. PMID 22521690 DOI: 10.1016/J.Molcel.2012.03.020  0.763
2012 Burke JE, Sashital DG, Zuo X, Wang YX, Butcher SE. Structure of the yeast U2/U6 snRNA complex. Rna (New York, N.Y.). 18: 673-83. PMID 22328579 DOI: 10.1261/Rna.031138.111  0.748
2012 Burke J, Sashital D, Zuo X, Wang Y, Butcher S. U2/U6 Helix I Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr17972  0.72
2012 Burke J, Sashital D, Zuo X, Wang Y, Butcher S. S. cerevisiae U2/U6 snRNA complex Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr17961  0.726
2011 Sashital DG, Jinek M, Doudna JA. An RNA-induced conformational change required for CRISPR RNA cleavage by the endoribonuclease Cse3. Nature Structural & Molecular Biology. 18: 680-7. PMID 21572442 DOI: 10.1038/Nsmb.2043  0.589
2010 Sashital DG, Doudna JA. Structural insights into RNA interference. Current Opinion in Structural Biology. 20: 90-7. PMID 20053548 DOI: 10.1016/J.Sbi.2009.12.001  0.536
2007 Sashital DG, Venditti V, Angers CG, Cornilescu G, Butcher SE. Structure and thermodynamics of a conserved U2 snRNA domain from yeast and human. Rna (New York, N.Y.). 13: 328-38. PMID 17242306 DOI: 10.1261/Rna.418407  0.769
2006 Sashital DG, Butcher SE. Flipping off the riboswitch: RNA structures that control gene expression. Acs Chemical Biology. 1: 341-5. PMID 17163768 DOI: 10.1021/Cb6002465  0.626
2005 Sashital DG, Cornilescu G, Butcher SE. Erratum: Corrigendum: U2–U6 RNA folding reveals a group II intron-like domain and a four-helix junction Nature Structural & Molecular Biology. 12: 99-99. DOI: 10.1038/Nsmb0105-99  0.619
2004 Sashital DG, Cornilescu G, McManus CJ, Brow DA, Butcher SE. U2-U6 RNA folding reveals a group II intron-like domain and a four-helix junction. Nature Structural & Molecular Biology. 11: 1237-42. PMID 15543154 DOI: 10.1038/Nsmb863  0.634
2004 Sigel RK, Sashital DG, Abramovitz DL, Palmer AG, Butcher SE, Pyle AM. Solution structure of domain 5 of a group II intron ribozyme reveals a new RNA motif. Nature Structural & Molecular Biology. 11: 187-92. PMID 14745440 DOI: 10.1038/Nsmb717  0.611
2004 Sigel R, Sashital D, Abramowitz D, Palmer A, Butcher S, Pyle AM. Chemical shifts assignments of domain 5 of the ai5gamma group II intron Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr5962  0.575
2003 Sashital DG, Allmann AM, Van Doren SR, Butcher SE. Structural basis for a lethal mutation in U6 RNA. Biochemistry. 42: 1470-7. PMID 12578359 DOI: 10.1021/Bi027137H  0.623
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