Xuebing Wu, Ph.D. - Publications

Affiliations: 
2010-2014 Koch Institute Massachusetts Institute of Technology, Cambridge, MA, United States 
 2014- Whitehead Institute Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
RNA
Website:
www.mit.edu/~wuxbl/

60 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Zhang C, Konermann S, Brideau NJ, Lotfy P, Wu X, Novick SJ, Strutzenberg T, Griffin PR, Hsu PD, Lyumkis D. Structural Basis for the RNA-Guided Ribonuclease Activity of CRISPR-Cas13d. Cell. 175: 212-223.e17. PMID 30241607 DOI: 10.1016/j.cell.2018.09.001  0.56
2018 Tycko J, Barrera LA, Huston NC, Friedland AE, Wu X, Gootenberg JS, Abudayyeh OO, Myer VE, Wilson CJ, Hsu PD. Publisher Correction: Pairwise library screen systematically interrogates Staphylococcus aureus Cas9 specificity in human cells. Nature Communications. 9: 3542. PMID 30154463 DOI: 10.1038/s41467-018-06029-z  0.4
2018 Tycko J, Barrera LA, Huston NC, Friedland AE, Wu X, Gootenberg JS, Abudayyeh OO, Myer VE, Wilson CJ, Hsu PD. Pairwise library screen systematically interrogates Staphylococcus aureus Cas9 specificity in human cells. Nature Communications. 9: 2962. PMID 30054474 DOI: 10.1038/s41467-018-05391-2  0.4
2018 Liu XS, Wu H, Krzisch M, Wu X, Graef J, Muffat J, Hnisz D, Li CH, Yuan B, Xu C, Li Y, Vershkov D, Cacace A, Young RA, Jaenisch R. Rescue of Fragile X Syndrome Neurons by DNA Methylation Editing of the FMR1 Gene. Cell. PMID 29456084 DOI: 10.1016/j.cell.2018.01.012  0.48
2018 Chiu AC, Suzuki HI, Wu X, Mahat DB, Kriz AJ, Sharp PA. Transcriptional Pause Sites Delineate Stable Nucleosome-Associated Premature Polyadenylation Suppressed by U1 snRNP. Molecular Cell. PMID 29398447 DOI: 10.1016/j.molcel.2018.01.006  0.92
2017 Wu X, Bartel DP. Widespread Influence of 3'-End Structures on Mammalian mRNA Processing and Stability. Cell. 169: 905-917.e11. PMID 28525757 DOI: 10.1016/j.cell.2017.04.036  0.92
2017 Wu X, Bartel DP. kpLogo: positional k-mer analysis reveals hidden specificity in biological sequences. Nucleic Acids Research. PMID 28460012 DOI: 10.1093/nar/gkx323  0.92
2016 Liu XS, Wu H, Ji X, Stelzer Y, Wu X, Czauderna S, Shu J, Dadon D, Young RA, Jaenisch R. Editing DNA Methylation in the Mammalian Genome. Cell. 167: 233-247.e17. PMID 27662091 DOI: 10.1016/j.cell.2016.08.056  0.92
2016 Zhang X, Chen MH, Wu X, Kodani A, Fan J, Doan R, Ozawa M, Ma J, Yoshida N, Reiter JF, Black DL, Kharchenko PV, Sharp PA, Walsh CA. Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex. Cell. 166: 1147-1162.e15. PMID 27565344 DOI: 10.1016/j.cell.2016.07.025  0.36
2015 Jiang L, Wang L, Li PF, Zhang XK, Chen JW, Qiu HJ, Wu XD, Zhang B. Positive expression of programmed death ligand-1 correlates with superior outcomes and might be a therapeutic target in primary pulmonary lymphoepithelioma-like carcinoma. Oncotargets and Therapy. 8: 1451-7. PMID 26109869 DOI: 10.2147/OTT.S84234  0.48
2015 Shi HF, Xu F, Shi Y, Ren CY, Wu XY, Xu B, Li J, Zhang DJ. Effect of ear-acupoint pressing and Ear Apex (HX6,7) bloodletting on haemorheology in chloasma patients with Gan depression pattern. Chinese Journal of Integrative Medicine. PMID 26108524 DOI: 10.1007/s11655-015-2109-2  0.32
2015 Wang B, Huang Y, Wu X, Li X. A Fuzzy Computing Model for Identifying Polarity of Chinese Sentiment Words. Computational Intelligence and Neuroscience. 2015: 525437. PMID 26106409 DOI: 10.1155/2015/525437  0.36
2015 Chen X, Zhu L, Xin L, Du K, Ran X, Cui X, Xiang Q, Zhang H, Xu P, Wu X. Rice stripe1-2 and stripe1-3 Mutants Encoding the Small Subunit of Ribonucleotide Reductase Are Temperature Sensitive and Are Required for Chlorophyll Biosynthesis. Plos One. 10: e0130172. PMID 26102588 DOI: 10.1371/journal.pone.0130172  0.36
2015 Chen J, Wu XT, Xu YQ, Zhong Y, Li YX, Chen JK, Li X, Nan P. Global transcriptome analysis profiles metabolic pathways in traditional herb Astragalus membranaceus Bge. var. mongolicus (Bge.) Hsiao. Bmc Genomics. 16: S15. PMID 26099797 DOI: 10.1186/1471-2164-16-S7-S15  0.36
2015 Zhang XS, Cao JQ, Zhao C, Wang XD, Wu XJ, Zhao YQ. Novel dammarane-type triterpenes isolated from hydrolyzate of total Gynostemma pentaphyllum saponins. Bioorganic & Medicinal Chemistry Letters. 25: 3095-9. PMID 26099540 DOI: 10.1016/j.bmcl.2015.06.022  0.4
2015 Wang C, Wu X, Shen F, Li Y, Zhang Y, Yu D. Shlnc-EC6 regulates murine erythroid enucleation by Rac1-PIP5K pathway. Development, Growth & Differentiation. 57: 466-73. PMID 26098172 DOI: 10.1111/dgd.12225  0.48
2015 Li Y, Yang L, Zheng Z, Shi J, Wu X, Guan H, Jia Y, Tao K, Wang H, Han S, Gao J, Zhao B, Su L, Hu D. MRP1 knockdown down-regulates the deposition of collagen and leads to a reduced hypertrophic scar fibrosis. Journal of Molecular Histology. PMID 26092470 DOI: 10.1007/s10735-015-9629-0  0.48
2015 Huang H, Cui W, Qiu W, Zhu M, Zhao R, Zeng D, Dong C, Wang X, Guo W, Xing W, Li X, Li L, Tan Y, Wu X, Chen L, et al. Impaired wound healing results from the dysfunction of the Akt/mTOR pathway in diabetic rats. Journal of Dermatological Science. PMID 26091964 DOI: 10.1016/j.jdermsci.2015.06.002  0.6
2015 Li L, Wang Y, Liu G, Wang M, Wu X. Context-Aware Reviewer Assignment for Trust Enhanced Peer Review. Plos One. 10: e0130493. PMID 26090849 DOI: 10.1371/journal.pone.0130493  0.44
2015 Zhang L, Lu Y, Ge Y, Shi Y, Wu X, Xu Q, Li X, Lu L, Zhang F, Yao G. Interleukin-23R rs7517847 T/G Polymorphism Contributes to the Risk of Crohn's Disease in Caucasians: A Meta-Analysis. Journal of Immunology Research. 2015: 279849. PMID 26090488 DOI: 10.1155/2015/279849  0.36
2015 Han P, Hu Y, Sun W, Zhang S, Li Y, Wu X, Yang Y, Zhu Q, Qin C, Li J, Jiang T. Mouse lung-adapted mutation of E190G in hemagglutinin from H5N1 influenza virus contributes to attenuation in mice. Journal of Medical Virology. PMID 26089289 DOI: 10.1002/jmv.24257  0.48
2015 Jiang H, Wu X, Wang H, Huang C, Zhang L. Combined Anti-PLGF and Anti-Endostatin Treatments Inhibit Ocular Hemangiomas. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 36: 930-6. PMID 26088746 DOI: 10.1159/000430267  0.32
2015 Liang Y, Jing X, Zeng Z, Bi W, Chen Y, Wu X, Yang L, Liu J, Xiao S, Liu S, Lin D, Tao E. Rifampicin attenuates rotenone-induced inflammation via suppressing NLRP3 inflammasome activation in microglia. Brain Research. PMID 26086368 DOI: 10.1016/j.brainres.2015.06.008  1
2015 Wu X, Wu Y, Wu K, Chen Y, Hu H, Yang M. Study on pyrolytic kinetics and behavior: The co-pyrolysis of microalgae and polypropylene. Bioresource Technology. 192: 522-8. PMID 26086085 DOI: 10.1016/j.biortech.2015.06.029  1
2015 Liu J, Li Z, Liu Z, Zhu F, Li W, Jiang H, Wu X, Song Y, Li S, Bai C. Exhaled nitric oxide from the central airway and alveoli in OSAHS patients: the potential correlations and clinical implications. Sleep & Breathing = Schlaf & Atmung. PMID 26084410 DOI: 10.1007/s11325-015-1198-7  0.44
2015 Ge H, Gardner J, Wu X, Rulifson I, Wang J, Xiong Y, Ye J, Belouski E, Cao P, Tang J, Lee KJ, Coberly S, Wu X, Gupte J, Miao L, et al. Trefoil Factor 3 (TFF3) Is Regulated by Food Intake, Improves Glucose Tolerance and Induces Mucinous Metaplasia. Plos One. 10: e0126924. PMID 26083576 DOI: 10.1371/journal.pone.0126924  0.48
2015 Xu Q, Li Q, Chen J, Zhang W, Wu X, Cao Y. [Effect of dopamine on the activity of matrix metalloproteinases and degradation of dentin collagen]. Zhonghua Kou Qiang Yi Xue Za Zhi = Zhonghua Kouqiang Yixue Zazhi = Chinese Journal of Stomatology. 50: 186-9. PMID 26081862  0.36
2015 Zhang Y, Liu B, Wu X, Li R, Ning X, Liu Y, Liu Z, Ge Z, Li R, Yin Y. New pyridin-3-ylmethyl carbamodithioic esters activate pyruvate kinase M2 and potential anticancer lead compounds. Bioorganic & Medicinal Chemistry. 23: 4815-23. PMID 26081759 DOI: 10.1016/j.bmc.2015.05.041  0.4
2015 Zhang M, Zhang H, Feng W, Wang Y, Yin S, Chen X, Wu X. [Endothelial progenitor cells promote osteogenic differentiation of marrow stromal cells in a paracrine manner]. Zhonghua Yi Xue Za Zhi. 95: 1253-7. PMID 26081513  0.36
2015 Chen S, Zha X, Shi L, Zhou L, Yang L, Li B, Wu X, Zhong J, Zhang T, Lu Y, Zhu K, Li Y. Upregulated TCRζ improves cytokine secretion in T cells from patients with AML. Journal of Hematology & Oncology. 8: 72. PMID 26081440 DOI: 10.1186/s13045-015-0170-0  0.48
2015 Fang M, Zhang J, Wu X, Huang X, Gu F, Qu X, Xu L. [The relationship between fat intake behavior and psychological impact factor in adolescent]. Zhonghua Yu Fang Yi Xue Za Zhi [Chinese Journal of Preventive Medicine]. 49: 156-60. PMID 26081402  0.6
2015 Liu Y, Sun J, Yang G, Liu Z, Guo S, Zhao R, Xu K, Wu X, Zhang Z. Downregulation of the expression of HDGF attenuates malignant biological behaviors of hilar cholangiocarcinoma cells. Molecular Medicine Reports. 12: 4713-9. PMID 26081074 DOI: 10.3892/mmr.2015.3922  0.4
2015 Gao WW, Xiao RQ, Peng BL, Xu HT, Shen HF, Huang MF, Shi TT, Yi J, Zhang WJ, Wu XN, Gao X, Lin XZ, Dorrestein PC, Rosenfeld MG, Liu W. Arginine methylation of HSP70 regulates retinoid acid-mediated RARβ2 gene activation. Proceedings of the National Academy of Sciences of the United States of America. 112: E3327-36. PMID 26080448 DOI: 10.1073/pnas.1509658112  0.32
2015 Xiao J, Cai Z, Li W, Yang Z, Gong J, Huang Y, Deng Y, Wu X, Wang L, Peng J, Ren D, Lan P, Wang J. Tumor Volume Reduction Rate Predicts Pathologic Tumor Response of Locally Advanced Rectal Cancer Treated with Neoadjuvant Chemotherapy alone: Results from a Prospective Trial. Journal of Cancer. 6: 636-42. PMID 26078794 DOI: 10.7150/jca.11738  0.48
2015 Li M, Li C, Liu Y, Chen Y, Wu X, Yu D, Werth VP, Williams KJ, Liu ML. Decreased secretion of adiponectin through its intracellular accumulation in adipose tissue during tobacco smoke exposure. Nutrition & Metabolism. 12: 15. PMID 26075006 DOI: 10.1186/s12986-015-0011-8  0.4
2015 Li X, Liu Y, Luo S, Wu B, Wu X, Han S. Mortality salience enhances racial in-group bias in empathic neural responses to others' suffering. Neuroimage. 118: 376-385. PMID 26074201 DOI: 10.1016/j.neuroimage.2015.06.023  0.4
2015 Yin F, Wu X, Li L, Chen Y, Lu T, Li W, Cai B, Yin W. Quality Control of Gardeniae Fructus by HPLC-PDA Fingerprint Coupled with Chemometric Methods. Journal of Chromatographic Science. PMID 26071608 DOI: 10.1093/chromsci/bmv072  1
2015 Zhao J, Guan H, Li M, Gu H, Qin J, Wu X. Significance of the ADC ratio in the differential diagnosis of breast lesions. Acta Radiologica (Stockholm, Sweden : 1987). PMID 26071495 DOI: 10.1177/0284185115590286  0.4
2015 Yu L, Wu X, Wei J, Liao Q, Xu L, Luo S, Zeng X, Zhao Y, Lv Z, Wu Z. Preliminary expression profile of cytokines in brain tissue of BALB/c mice with Angiostrongylus cantonensis infection. Parasites & Vectors. 8: 328. PMID 26070790 DOI: 10.1186/s13071-015-0939-6  0.6
2015 Wu X, Zhang Q, Wang H, Hu J. Predicting carcinogenicity of organic compounds based on CPDB. Chemosphere. 139: 81-90. PMID 26070146 DOI: 10.1016/j.chemosphere.2015.05.056  0.36
2015 Shen J, Peng Y, Wei L, Zhang W, Yang L, Lan L, Kapoor P, Ju Z, Mo Q, Shih IeM, Uray IP, Wu X, Brown PH, Shen X, Mills GB, et al. ARID1A Deficiency Impairs the DNA Damage Checkpoint and Sensitizes Cells to PARP Inhibitors. Cancer Discovery. 5: 752-67. PMID 26069190 DOI: 10.1158/2159-8290.CD-14-0849  0.36
2015 Luo X, Wasilko DJ, Liu Y, Sun J, Wu X, Luo ZQ, Mao Y. Structure of the Legionella Virulence Factor, SidC Reveals a Unique PI(4)P-Specific Binding Domain Essential for Its Targeting to the Bacterial Phagosome. Plos Pathogens. 11: e1004965. PMID 26067986 DOI: 10.1371/journal.ppat.1004965  0.4
2015 Chen Y, Sun R, Wu X, Cheng M, Wei H, Tian Z. CD4+CD25+ Regulatory T Cells Inhibit Natural Killer Cell Hepatocytotoxicity of Hepatitis B Virus Transgenic Mice via Membrane-Bound TGF-β and OX40. Journal of Innate Immunity. PMID 26067079 DOI: 10.1159/000431150  0.32
2015 Xu L, Xia W, Wu X, Wang X, Zhao L, Nie M. Chimeric CYP11B2/CYP11B1 causing 11β-hydroxylase deficiency in Chinese patients with congenital adrenal hyperplasia. Steroids. 101: 51-5. PMID 26066897 DOI: 10.1016/j.steroids.2015.06.002  0.6
2015 Xing B, Wang L, Li Q, Cao Y, Dong X, Liang J, Wu X. Human embryonic stem cell-derived pancreatic endoderm alleviates diabetic pathology and improves reproductive outcome in C57BL/KsJ-Lep(db/+) gestational diabetes mellitus mice. Nutrition Research (New York, N.Y.). 35: 603-9. PMID 26066567 DOI: 10.1016/j.nutres.2015.05.009  0.48
2015 Peng J, Chen Y, Wu X, Zhang Q, Kan B, Chen X, Chen Y, Huang J, Liang Z. Correlating Molecular Structures with Transport Dynamics in High-Efficiency Small-Molecule Organic Photovoltaics. Acs Applied Materials & Interfaces. 7: 13137-41. PMID 26066398 DOI: 10.1021/acsami.5b03073  1
2015 Ran FA, Cong L, Yan WX, Scott DA, Gootenberg JS, Kriz AJ, Zetsche B, Shalem O, Wu X, Makarova KS, Koonin EV, Sharp PA, Zhang F. In vivo genome editing using Staphylococcus aureus Cas9. Nature. 520: 186-91. PMID 25830891 DOI: 10.1038/nature14299  0.92
2014 Wu X, Kriz AJ, Sharp PA. Target specificity of the CRISPR-Cas9 system. Quantitative Biology. 2: 59-70. PMID 25722925 DOI: 10.1007/s40484-014-0030-x  0.92
2014 Chen S, Xue Y, Wu X, Le C, Bhutkar A, Bell EL, Zhang F, Langer R, Sharp PA. Global microRNA depletion suppresses tumor angiogenesis. Genes & Development. 28: 1054-67. PMID 24788094 DOI: 10.1101/gad.239681.114  0.36
2014 Wu X, Scott DA, Kriz AJ, Chiu AC, Hsu PD, Dadon DB, Cheng AW, Trevino AE, Konermann S, Chen S, Jaenisch R, Zhang F, Sharp PA. Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells. Nature Biotechnology. 32: 670-6. PMID 24752079 DOI: 10.1038/nbt.2889  0.92
2013 Chen Y, Wu X, Jiang R. Integrating human omics data to prioritize candidate genes. Bmc Medical Genomics. 6: 57. PMID 24344781 DOI: 10.1186/1755-8794-6-57  1
2013 Wu X, Sharp PA. Divergent transcription: a driving force for new gene origination? Cell. 155: 990-6. PMID 24267885 DOI: 10.1016/j.cell.2013.10.048  0.92
2013 Lyubimova A, Itzkovitz S, Junker JP, Fan ZP, Wu X, van Oudenaarden A. Single-molecule mRNA detection and counting in mammalian tissue. Nature Protocols. 8: 1743-58. PMID 23949380 DOI: 10.1038/nprot.2013.109  0.92
2013 Hsu PD, Scott DA, Weinstein JA, Ran FA, Konermann S, Agarwala V, Li Y, Fine EJ, Wu X, Shalem O, Cradick TJ, Marraffini LA, Bao G, Zhang F. DNA targeting specificity of RNA-guided Cas9 nucleases. Nature Biotechnology. 31: 827-32. PMID 23873081 DOI: 10.1038/nbt.2647  0.92
2013 Almada AE, Wu X, Kriz AJ, Burge CB, Sharp PA. Promoter directionality is controlled by U1 snRNP and polyadenylation signals. Nature. 499: 360-3. PMID 23792564 DOI: 10.1038/nature12349  0.92
2013 Cong L, Ran FA, Cox D, Lin S, Barretto R, Habib N, Hsu PD, Wu X, Jiang W, Marraffini LA, Zhang F. Multiplex genome engineering using CRISPR/Cas systems. Science (New York, N.Y.). 339: 819-23. PMID 23287718 DOI: 10.1126/science.1231143  0.92
2009 Tang W, Wu X, Jiang R, Li Y. Epistatic module detection for case-control studies: a Bayesian model with a Gibbs sampling strategy. Plos Genetics. 5: e1000464. PMID 19412524 DOI: 10.1371/journal.pgen.1000464  1
2009 Jiang R, Tang W, Wu X, Fu W. A random forest approach to the detection of epistatic interactions in case-control studies. Bmc Bioinformatics. 10: S65. PMID 19208169 DOI: 10.1186/1471-2105-10-S1-S65  1
2009 Wu X, Liu Q, Jiang R. Align human interactome with phenome to identify causative genes and networks underlying disease families. Bioinformatics (Oxford, England). 25: 98-104. PMID 19010805 DOI: 10.1093/bioinformatics/btn593  1
2008 Wu X, Jiang R, Zhang MQ, Li S. Network-based global inference of human disease genes. Molecular Systems Biology. 4: 189. PMID 18463613 DOI: 10.1038/msb.2008.27  1
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