| Year |
Citation |
Score |
| 2023 |
Aseem SO, Hylemon PB, Zhou H. Bile Acids and Biliary Fibrosis. Cells. 12. PMID 36899928 DOI: 10.3390/cells12050792 |
0.304 |
|
| 2021 |
Hylemon PB, Su L, Zheng PC, Bajaj JS, Zhou H. Bile Acids, Gut Microbiome and the Road to Fatty Liver Disease. Comprehensive Physiology. 12: 2719-2730. PMID 34964117 DOI: 10.1002/cphy.c210024 |
0.301 |
|
| 2021 |
Wang Y, Tai YL, Zhao D, Zhang Y, Yan J, Kakiyama G, Wang X, Gurley EC, Liu J, Liu J, Liu J, Lai G, Hylemon PB, Pandak WM, Chen W, et al. Berberine Prevents Disease Progression of Nonalcoholic Steatohepatitis through Modulating Multiple Pathways. Cells. 10. PMID 33494295 DOI: 10.3390/cells10020210 |
0.31 |
|
| 2020 |
Wang Y, Chen L, Pandak WM, Heuman D, Hylemon PB, Ren S. High Glucose Induces Lipid Accumulation via 25-Hydroxycholesterol DNA-CpG Methylation. Iscience. 23: 101102. PMID 32408171 DOI: 10.1016/J.Isci.2020.101102 |
0.345 |
|
| 2020 |
Wang Y, Zhou X, Zhao D, Wang X, Gurley EC, Liu R, Li X, Hylemon PB, Chen W, Zhou H. Berberine inhibits free fatty acid and LPS-induced inflammation via modulating ER stress response in macrophages and hepatocytes. Plos One. 15: e0232630. PMID 32357187 DOI: 10.1371/Journal.Pone.0232630 |
0.36 |
|
| 2020 |
Li X, Liu R, Wang Y, Zhu W, Zhao D, Wang X, Yang H, Gurley EC, Chen W, Hylemon PB, Zhou H. Cholangiocyte-Derived Exosomal lncRNA H19 Promotes Macrophage Activation and Hepatic Inflammation under Cholestatic Conditions. Cells. 9. PMID 31940841 DOI: 10.3390/Cells9010190 |
0.334 |
|
| 2020 |
Wang Y, Xiang D, Chen W, Zhao D, Gurley E, Wang X, Pu G, Tai Y, Zhang Y, Chen Z, Wu J, Yan J, Hylemon PB, Zhou H. Berberine attenuates cholestatic liver and bile duct injury in Mdr2
−/−
mice by maintaining bile acid homeostasis The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04758 |
0.331 |
|
| 2020 |
Zhang Y, Kang D, Zhao D, Yan J, Ghosh S, Sikaroodi M, Tai Y, Wang Y, Gurley E, Liu R, Gillevet PM, Hylemon P, Zhou H, Bajaj JS. Su1592 NEURO AND HEPATIC INFLAMMATION AND STEATOSIS ARE MODULATED BY GUT MICROBIAL CHANGES AFTER ISOLATED HEPATIC VAGOTOMY AND ANTIBIOTICS IN CIRRHOSIS Gastroenterology. 158: S-1349-S-1350. DOI: 10.1016/S0016-5085(20)34045-2 |
0.321 |
|
| 2020 |
Wang Y, Ge P, Tai Y, Wu J, Zhang Y, Zhao D, Wang X, Gurley E, Hylemon P, Chen W, Zhou H. 321 HEPATIC HUR PROTECTS AGAINST DIET-INDUCED LIPID METABOLISM DISORDER Gastroenterology. 158: S-1266. DOI: 10.1016/S0016-5085(20)33823-3 |
0.319 |
|
| 2020 |
Zhang Y, Wang R, Wang Y, Tai Y, Ge P, Wu J, Yang W, Zhao D, Wang X, Gurley E, Hylemon P, Wang W, Zhou H. 215 BILE ACID-INDUCED UPREGULATION OF MICRORNA 155 PROMOTES CHOLESTATIC LIVER INJURY VIA TARGETING THE INSIG2/SREBP1 PATHWAY IN MDR2-/- MICE. Gastroenterology. 158: S-1262. DOI: 10.1016/S0016-5085(20)33810-5 |
0.357 |
|
| 2019 |
Liu R, Kang JD, Sartor RB, Sikaroodi M, Fagan A, Gavis EA, Zhou H, Hylemon PB, Herzog JW, Li X, Lippman RH, Maeso JG, Wade JB, Ghosh S, Gurley E, et al. Neuroinflammation in Murine Cirrhosis is Dependent on the Gut Microbiome and is Attenuated by Fecal Transplant. Hepatology (Baltimore, Md.). PMID 31220352 DOI: 10.1002/Hep.30827 |
0.345 |
|
| 2019 |
Xiao Y, Liu R, Li X, Gurley EC, Hylemon PB, Lu Y, Zhou H, Cai W. Long non-coding RNA H19 contributes to cholangiocyte proliferation and cholestatic liver fibrosis in biliary atresia. Hepatology (Baltimore, Md.). PMID 31063660 DOI: 10.1002/Hep.30698 |
0.339 |
|
| 2019 |
Kwong EK, Liu R, Zhao D, Li X, Zhu W, Wang X, Gurley EC, Lai G, Liu J, Hylemon PB, Zhou H. The role of sphingosine kinase 2 in alcoholic liver disease. Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association For the Study of the Liver. PMID 31003959 DOI: 10.1016/J.Dld.2019.03.020 |
0.376 |
|
| 2019 |
Liu R, Li X, Zhu W, Wang Y, Zhao D, Wang X, Gurley EC, Liang G, Chen W, Lai G, Pandak WM, Lippman HR, Bajaj JS, Hylemon PB, Zhou H. Cholangiocyte-derived exosomal LncRNA H19 promotes hepatic stellate cell activation and cholestatic liver fibrosis. Hepatology (Baltimore, Md.). PMID 30985008 DOI: 10.1002/Hep.30662 |
0.316 |
|
| 2019 |
Gaidos J, Kang JD, Kakiyama G, Pandak WM, Hylemon PB. 747 Pilot Study of Gut Dysbiosis and Bile Acid Dysmetabolism in Active Ulcerative Colitis American Journal of Gastroenterology. 114: S438-S438. DOI: 10.14309/01.Ajg.0000592524.80798.9B |
0.412 |
|
| 2019 |
Bajaj JS, Fagan A, Sikaroodi M, Kakiyama G, Pandak W, Takei H, Gavis E, Hylemon P, Heuman D, Nittono H, Gillevet P. SAT-012-Alterations in skin microbiota, serum bile acids and autotaxin modulate itching intensity in patients with cirrhosis Journal of Hepatology. 70: e630. DOI: 10.1016/S0618-8278(19)31255-1 |
0.361 |
|
| 2019 |
Liu R, Li X, Zhu W, Zhao D, Wang Y, Kwong E, Alruwaili W, Hinton M, Yang H, Xiang D, Wang X, Gurley E, Pandak WM, Hylemon P, Zhou H. 771 – Bile Acid-Induced Activation of Sphingosine Kinase 2 Contributes to Intestinal Barrier Dysfunction and Hepatic Inflammation in Multi-Drug Resistance 2 Gene Deficient Mice Gastroenterology. 156: S-1215. DOI: 10.1016/S0016-5085(19)40022-X |
0.359 |
|
| 2019 |
Bajaj JS, Fagan A, Sikaroodi M, Kakiyama G, Pandak WM, Nittono H, Takei H, Gavis E, Hylemon P, Heuman D, Gillevet PM. 408 – Alterations in Skin Microbiota, Serum Bile Acids and Autotaxin Modulate Itching Intensity in Patients with Cirrhosis Gastroenterology. 156: S-1196-S-1197. DOI: 10.1016/S0016-5085(19)39968-8 |
0.357 |
|
| 2018 |
Kang JD, Myers CJ, Harris SC, Kakiyama G, Lee IK, Yun BS, Matsuzaki K, Furukawa M, Min HK, Bajaj JS, Zhou H, Hylemon PB. Bile Acid 7α-Dehydroxylating Gut Bacteria Secrete Antibiotics that Inhibit Clostridium difficile: Role of Secondary Bile Acids. Cell Chemical Biology. PMID 30482679 DOI: 10.1016/J.Chembiol.2018.10.003 |
0.413 |
|
| 2018 |
Liu R, Li X, Hylemon PB, Zhou H. Conjugated bile acids promote invasive growth of esophageal adenocarcinoma cells and cancer stem cell expansion via sphingosine 1-phosphate receptor 2 (S1PR2)-mediated YAP activation. The American Journal of Pathology. PMID 29963993 DOI: 10.1016/J.Ajpath.2018.05.015 |
0.311 |
|
| 2018 |
Bajaj JS, Acharya C, Fagan A, White MB, Gavis E, Heuman DM, Hylemon PB, Fuchs M, Puri P, Schubert ML, Sanyal AJ, Sterling RK, Stravitz RT, Siddiqui MS, Luketic V, et al. Proton Pump Inhibitor Initiation and Withdrawal affects Gut Microbiota and Readmission Risk in Cirrhosis. The American Journal of Gastroenterology. PMID 29872220 DOI: 10.1038/S41395-018-0085-9 |
0.304 |
|
| 2018 |
Hylemon PB, Harris SC, Ridlon JM. Metabolism of hydrogen gases and bile acids in the gut microbiome. Febs Letters. PMID 29683480 DOI: 10.1002/1873-3468.13064 |
0.668 |
|
| 2018 |
Bajaj JS, Kakiyama G, Savidge T, Takei H, Kassam ZA, Fagan A, Gavis EA, Pandak WM, Nittono H, Hylemon PB, Boonma P, Haag A, Heuman DM, Fuchs M, John B, et al. Antibiotic-Associated Disruption of Microbiota Composition and Function in Cirrhosis is Restored by Fecal Transplant. Hepatology (Baltimore, Md.). PMID 29665102 DOI: 10.1002/Hep.30037 |
0.339 |
|
| 2018 |
Harris SC, Devendran S, Méndez-García C, Mythen SM, Wright CL, Fields CJ, Hernandez AG, Cann I, Hylemon PB, Ridlon JM. Bile acid oxidation by Eggerthella lenta strains C592 and DSM 2243. Gut Microbes. 1-58. PMID 29617190 DOI: 10.1080/19490976.2018.1458180 |
0.676 |
|
| 2018 |
Bajaj JS, Kakiyama G, Cox IJ, Nittono H, Takei H, White M, Fagan A, Gavis EA, Heuman DM, Gilles HC, Hylemon P, Taylor-Robinson SD, Legido-Quigley C, Kim M, Xu J, et al. Alterations in Gut Microbial Function Following Liver Transplant. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. PMID 29500907 DOI: 10.1002/Lt.25046 |
0.305 |
|
| 2018 |
Li X, Liu R, Huang Z, Gurley EC, Wang X, Wang J, He H, Yang H, Lai G, Zhang L, Bajaj JS, White M, Pandak WM, Hylemon PB, Zhou H. Cholangiocyte-derived exosomal long noncoding RNA H19 promotes cholestatic liver injury in mouse and human. Hepatology (Baltimore, Md.). PMID 29425397 DOI: 10.1002/Hep.29838 |
0.303 |
|
| 2018 |
Harris S, Devendran S, Ridlon JM, Hylemon P. 180 - Eggerthella Lenta Modulates Gut Microbial Physiology by Linking Bile Acid Metabolism to Acetogenesis Gastroenterology. 154: S-46. DOI: 10.1016/S0016-5085(18)30623-1 |
0.681 |
|
| 2017 |
Bajaj JS, Hylemon PB. Gut-Liver Axis Alterations in Alcoholic Liver Disease: Are Bile Acids the Answer? Hepatology (Baltimore, Md.). PMID 29272041 DOI: 10.1002/Hep.29760 |
0.367 |
|
| 2017 |
Harris SC, Devendran S, Alves JMP, Mythen SM, Hylemon PB, Ridlon JM. Identification of a gene encoding a flavoprotein involved in bile acid metabolism by the human gut bacterium Clostridium scindens ATCC 35704. Biochimica Et Biophysica Acta. PMID 29217478 DOI: 10.1016/J.Bbalip.2017.12.001 |
0.685 |
|
| 2017 |
Kwong EK, Li X, Hylemon PB, Zhou H. Sphingosine Kinases/Sphingosine 1-Phosphate Signaling in Hepatic Lipid Metabolism. Current Pharmacology Reports. 3: 176-183. PMID 29130028 DOI: 10.1007/S40495-017-0093-2 |
0.361 |
|
| 2017 |
Hylemon PB, Takabe K, Dozmorov M, Nagahashi M, Zhou H. Bile acids as global regulators of hepatic nutrient metabolism. Liver Research. 1: 10-16. PMID 29123941 DOI: 10.1016/J.Livres.2017.03.002 |
0.387 |
|
| 2017 |
Liu R, Li X, Huang Z, Zhao D, Ganesh BS, Lai G, Pandak WM, Hylemon PB, Bajaj JS, Sanyal AJ, Zhou H. CHOP-induced loss of intestinal epithelial stemness contributes to bile duct ligation-induced cholestatic liver injury. Hepatology (Baltimore, Md.). PMID 28926118 DOI: 10.1002/Hep.29540 |
0.359 |
|
| 2017 |
Bajaj JS, Kakiyama G, Zhao D, Takei H, Fagan A, Hylemon P, Zhou H, Pandak WM, Nittono H, Fiehn O, Salzman N, Holtz M, Simpson P, Gavis EA, Heuman DM, et al. Continued Alcohol Misuse in Human Cirrhosis is Associated with An Impaired Gut-Liver Axis. Alcoholism, Clinical and Experimental Research. PMID 28925102 DOI: 10.1111/Acer.13498 |
0.309 |
|
| 2017 |
Puri P, Daita K, Joyce A, Mirshahi F, Santhekadur PK, Cazanave S, Luketic VA, Siddiqui MS, Boyett S, Min HK, Kumar DP, Kohli R, Zhou H, Hylemon PB, Contos MJ, et al. The presence and severity of nonalcoholic steatohepatitis is associated with specific changes in circulating bile acids. Hepatology (Baltimore, Md.). PMID 28696585 DOI: 10.1002/Hep.29359 |
0.341 |
|
| 2017 |
Yang J, Sun L, Wang L, Hassan HM, Wang X, Hylemon PB, Wang T, Zhou H, Zhang L, Jiang Z. Activation of Sirt1/FXR Signaling Pathway Attenuates Triptolide-Induced Hepatotoxicity in Rats. Frontiers in Pharmacology. 8: 260. PMID 28536529 DOI: 10.3389/Fphar.2017.00260 |
0.428 |
|
| 2017 |
Wang Y, Aoki H, Yang J, Peng K, Liu R, Li X, Qiang X, Sun L, Gurley EC, Lai G, Zhang L, Liang G, Nagahashi M, Takabe K, Pandak WM, ... Hylemon PB, et al. The role of S1PR2 in bile acid-induced cholangiocyte proliferation and cholestasis-induced liver injury in mice. Hepatology (Baltimore, Md.). PMID 28120434 DOI: 10.1002/Hep.29076 |
0.385 |
|
| 2017 |
Chen T, Huang Z, Liu R, Yang J, Hylemon PB, Zhou H. Sphingosine-1 phosphate promotes intestinal epithelial cell proliferation via S1PR2. Frontiers in Bioscience (Landmark Edition). 22: 596-608. PMID 27814635 DOI: 10.2741/4505 |
0.313 |
|
| 2017 |
Kakiyama G, Marques D, Takei H, Nittono H, Liu X, Green RM, Erickson S, Rodriguez-Agudo D, Gil G, Bajaj JS, Hylemon P, Zhou H, Pandak WM. Inflammasome Activation by Chronic Down Regulation of CYP7B1 and its Causative Increased Oxysterol Accumulation, Represents the Key Initial Step in Fatty Liver's Progression Toward Inflammation Gastroenterology. 152: S1069. DOI: 10.1016/S0016-5085(17)33610-7 |
0.364 |
|
| 2016 |
Kang DJ, Kakiyama G, Betrapally NS, Herzog J, Nittono H, Hylemon PB, Zhou H, Carroll I, Yang J, Gillevet PM, Jiao C, Takei H, Pandak WM, Iida T, Heuman DM, et al. Rifaximin Exerts Beneficial Effects Independent of its Ability to Alter Microbiota Composition. Clinical and Translational Gastroenterology. 7: e187. PMID 27560928 DOI: 10.1038/Ctg.2016.44 |
0.334 |
|
| 2016 |
Nagahashi M, Yuza K, Hirose Y, Nakajima M, Ramanathan R, Hait NC, Hylemon PB, Zhou H, Takabe K, Wakai T. The roles of bile acids and sphingosine-1-phosphate signaling in the hepato-biliary diseases. Journal of Lipid Research. PMID 27459945 DOI: 10.1194/Jlr.R069286 |
0.419 |
|
| 2016 |
Kang DJ, Betrapally NS, Ghosh SA, Sartor RB, Hylemon PB, Gillevet PM, Sanyal AJ, Heuman DM, Carl D, Zhou H, Liu R, Wang X, Yang J, Jiao C, Herzog J, et al. Gut microbiota drive the development of neuro-inflammatory response in cirrhosis. Hepatology (Baltimore, Md.). PMID 27339732 DOI: 10.1002/Hep.28696 |
0.321 |
|
| 2016 |
Li X, Liu R, Luo L, Yu L, Chen X, Sun L, Wang T, Hylemon PB, Zhou H, Jiang Z, Zhang L. Role of AMP-activated protein kinase α1 in 17α-ethinylestradiol-induced cholestasis in rats. Archives of Toxicology. PMID 27090119 DOI: 10.1007/S00204-016-1697-8 |
0.369 |
|
| 2016 |
Ridlon JM, Harris SC, Bhowmik S, Kang DJ, Hylemon PB. Consequences of bile salt biotransformations by intestinal bacteria. Gut Microbes. 7: 22-39. PMID 26939849 DOI: 10.1080/19490976.2015.1127483 |
0.714 |
|
| 2015 |
Bhowmik S, Chiu HP, Jones DH, Chiu HJ, Miller MD, Xu Q, Farr CL, Ridlon JM, Wells JE, Elsliger MA, Wilson IA, Hylemon PB, Lesley SA. Structure and Functional Characterization of a Bile Acid 7α Dehydratase BaiE in Secondary Bile Acid Synthesis. Proteins. PMID 26650892 DOI: 10.1002/Prot.24971 |
0.688 |
|
| 2015 |
Kwong E, Li Y, Hylemon PB, Zhou H. Bile acids and sphingosine-1-phosphate receptor 2 in hepatic lipid metabolism. Acta Pharmaceutica Sinica. B. 5: 151-157. PMID 26579441 DOI: 10.1016/J.Apsb.2014.12.009 |
0.407 |
|
| 2015 |
Liu R, Li X, Luo L, Qiang X, Hylemon PB, Jiang Z, Zhang L, Zhou H. Taurocholate Induces Cyclooxygenase-2 Expression via the Sphingosine 1-phosphate Receptor 2 in a Human Cholangiocarcinoma Cell Line. The Journal of Biological Chemistry. PMID 26518876 DOI: 10.1074/Jbc.M115.668277 |
0.333 |
|
| 2015 |
Kang DJ, Hylemon PB, Bajaj JS. Fecal transplant to mitigate hyperammonemia and hepatic encephalopathy in animal models. Annals of Hepatology. 14: 762-3. PMID 26256908 DOI: 10.1016/S1665-2681(19)30774-4 |
0.316 |
|
| 2015 |
Ridlon JM, Kang DJ, Hylemon PB, Bajaj JS. Gut microbiota, cirrhosis, and alcohol regulate bile acid metabolism in the gut. Digestive Diseases (Basel, Switzerland). 33: 338-45. PMID 26045267 DOI: 10.1159/000371678 |
0.705 |
|
| 2015 |
Gu S, Cao B, Sun R, Tang Y, Paletta JL, Wu XL, Liu L, Zha W, Zhao C, Li Y, Ridlon JM, Hylemon PB, Zhou H, Aa J, Wang G. Correction: A metabolomic and pharmacokinetic study on the mechanism underlying the lipid-lowering effect of orally administered berberine. Molecular Biosystems. 11: 664. PMID 26039924 DOI: 10.1039/c4mb90042a |
0.586 |
|
| 2015 |
Bajaj JS, Betrapally NS, Hylemon PB, Heuman DM, Daita K, White MB, Unser A, Thacker LR, Sanyal AJ, Kang DJ, Sikaroodi M, Gillevet PM. Salivary microbiota reflects changes in gut microbiota in cirrhosis with hepatic encephalopathy. Hepatology (Baltimore, Md.). PMID 25820757 DOI: 10.1002/Hep.27819 |
0.341 |
|
| 2015 |
Gu S, Cao B, Sun R, Tang Y, Paletta JL, Wu XL, Liu L, Zha W, Zhao C, Li Y, Ridlon JM, Hylemon PB, Zhou H, Aa J, Wang G. Correction: A metabolomic and pharmacokinetic study on the mechanism underlying the lipid-lowering effect of orally administered berberine. Molecular Biosystems. 11: 664. PMID 25535027 DOI: 10.1039/C4Mb90042A |
0.609 |
|
| 2015 |
Gu S, Cao B, Sun R, Tang Y, Paletta JL, Wu XL, Liu L, Zha W, Zhao C, Li Y, Radlon JM, Hylemon PB, Zhou H, Aa J, Wang G. A metabolomic and pharmacokinetic study on the mechanism underlying the lipid-lowering effect of orally administered berberine. Molecular Biosystems. 11: 463-74. PMID 25411028 DOI: 10.1039/c4mb00500g |
0.322 |
|
| 2015 |
Nagahashi M, Takabe K, Liu R, Peng K, Wang X, Wang Y, Hait NC, Wang X, Allegood JC, Yamada A, Aoyagi T, Liang J, Pandak WM, Spiegel S, Hylemon PB, et al. Conjugated bile acid-activated S1P receptor 2 is a key regulator of sphingosine kinase 2 and hepatic gene expression. Hepatology (Baltimore, Md.). 61: 1216-26. PMID 25363242 DOI: 10.1002/Hep.27592 |
0.409 |
|
| 2015 |
Kang D, Hylemon P, Sartor R, Kakiyama G, Gillevet P, Heuman D, Pandak W, Ridlon J, Fiehn O, Grapov D, Bajaj J. O090 : Humanization of germ-free mice with alcoholic cirrhotic microbiota, but not healthy microbiota, induces bacterial translocation and a pro-inflammatory milieu, which is ameliorated with lactobacillus GG Journal of Hepatology. 62: S239-S240. DOI: 10.1016/S0168-8278(15)30109-4 |
0.59 |
|
| 2015 |
Kang D, Hylemon P, Ridlon JM, Pandak WM, Heuman DM, Bajaj JS. Sa1017 Diminished Fecal Secondary Bile Acids May Predispose Patients With Cirrhosis to C. difficile Infection and Attenuate the Action of Rifaximin Gastroenterology. 148: S-1008. DOI: 10.1016/S0016-5085(15)33439-9 |
0.649 |
|
| 2015 |
Kang D, Hylemon P, Sartor RB, Kakiyama G, Gillevet PM, Heuman DM, Pandak WM, Ridlon JM, Grapov D, Fiehn O, Bajaj JS. 281 Humanization of Germ-Free Mice With Alcoholic Cirrhotic Microbiota, but Not Healthy Microbiota, Induces Bacterial Translocation and a Pro-Inflammatory Milieu, Which Is Ameliorated With Lactobacillus GG Gastroenterology. 148: S-975-S-976. DOI: 10.1016/S0016-5085(15)33333-3 |
0.627 |
|
| 2014 |
Bajaj JS, Cox IJ, Betrapally NS, Heuman DM, Schubert ML, Ratneswaran M, Hylemon PB, White MB, Daita K, Noble NA, Sikaroodi M, Williams R, Crossey MM, Taylor-Robinson SD, Gillevet PM. Systems biology analysis of omeprazole therapy in cirrhosis demonstrates significant shifts in gut microbiota composition and function. American Journal of Physiology. Gastrointestinal and Liver Physiology. 307: G951-7. PMID 25258407 DOI: 10.1152/Ajpgi.00268.2014 |
0.33 |
|
| 2014 |
Srivastava J, Robertson CL, Rajasekaran D, Gredler R, Siddiq A, Emdad L, Mukhopadhyay ND, Ghosh S, Hylemon PB, Gil G, Shah K, Bhere D, Subler MA, Windle JJ, Fisher PB, et al. AEG-1 regulates retinoid X receptor and inhibits retinoid signaling. Cancer Research. 74: 4364-77. PMID 25125681 DOI: 10.1158/0008-5472.Can-14-0421 |
0.306 |
|
| 2014 |
Zhou H, Hylemon PB. Bile acids are nutrient signaling hormones. Steroids. 86: 62-8. PMID 24819989 DOI: 10.1016/J.Steroids.2014.04.016 |
0.413 |
|
| 2014 |
Liu R, Zhao R, Zhou X, Liang X, Campbell DJ, Zhang X, Zhang L, Shi R, Wang G, Pandak WM, Sirica AE, Hylemon PB, Zhou H. Conjugated bile acids promote cholangiocarcinoma cell invasive growth through activation of sphingosine 1-phosphate receptor 2. Hepatology (Baltimore, Md.). 60: 908-18. PMID 24700501 DOI: 10.1002/Hep.27085 |
0.369 |
|
| 2014 |
Kakiyama G, Hylemon PB, Zhou H, Pandak WM, Heuman DM, Kang DJ, Takei H, Nittono H, Ridlon JM, Fuchs M, Gurley EC, Wang Y, Liu R, Sanyal AJ, Gillevet PM, et al. Colonic inflammation and secondary bile acids in alcoholic cirrhosis. American Journal of Physiology. Gastrointestinal and Liver Physiology. 306: G929-37. PMID 24699327 DOI: 10.1152/Ajpgi.00315.2013 |
0.64 |
|
| 2014 |
Ridlon JM, Kang DJ, Hylemon PB, Bajaj JS. Bile acids and the gut microbiome. Current Opinion in Gastroenterology. 30: 332-8. PMID 24625896 DOI: 10.1097/Mog.0000000000000057 |
0.687 |
|
| 2014 |
Bajaj JS, Heuman DM, Hylemon PB, Sanyal AJ, White MB, Monteith P, Noble NA, Unser AB, Daita K, Fisher AR, Sikaroodi M, Gillevet PM. Altered profile of human gut microbiome is associated with cirrhosis and its complications. Journal of Hepatology. 60: 940-7. PMID 24374295 DOI: 10.1016/J.Jhep.2013.12.019 |
0.312 |
|
| 2014 |
Bajaj J, Heuman D, Hylemon P, Sikaroodi M, Ridlon J, Pandak W, Schubert M, Fuchs M, White M, Daita K, Gillevet P. P335 DYSFUNCTIONAL GUT MICROBIOTA IN ILEO-COLONIC MUCOSA AND STOOL IN ALCOHOLIC CIRRHOSIS IS ASSOCIATED WITH ENDOTOXEMIA: IMPLICATIONS FOR BACTERIAL TRANSLOCATION Journal of Hepatology. 60: S178-S179. DOI: 10.1016/S0168-8278(14)60497-9 |
0.625 |
|
| 2013 |
Ridlon JM, Alves JM, Hylemon PB, Bajaj JS. Cirrhosis, bile acids and gut microbiota: unraveling a complex relationship. Gut Microbes. 4: 382-7. PMID 23851335 DOI: 10.4161/Gmic.25723 |
0.709 |
|
| 2013 |
Ridlon JM, Ikegawa S, Alves JM, Zhou B, Kobayashi A, Iida T, Mitamura K, Tanabe G, Serrano M, De Guzman A, Cooper P, Buck GA, Hylemon PB. Clostridium scindens: a human gut microbe with a high potential to convert glucocorticoids into androgens. Journal of Lipid Research. 54: 2437-49. PMID 23772041 DOI: 10.1194/Jlr.M038869 |
0.65 |
|
| 2013 |
Bajaj JS, Heuman DM, Sanyal AJ, Hylemon PB, Sterling RK, Stravitz RT, Fuchs M, Ridlon JM, Daita K, Monteith P, Noble NA, White MB, Fisher A, Sikaroodi M, Rangwala H, et al. Modulation of the metabiome by rifaximin in patients with cirrhosis and minimal hepatic encephalopathy. Plos One. 8: e60042. PMID 23565181 DOI: 10.1371/Journal.Pone.0060042 |
0.645 |
|
| 2013 |
Kakiyama G, Pandak WM, Gillevet PM, Hylemon PB, Heuman DM, Daita K, Takei H, Muto A, Nittono H, Ridlon JM, White MB, Noble NA, Monteith P, Fuchs M, Thacker LR, et al. Modulation of the fecal bile acid profile by gut microbiota in cirrhosis. Journal of Hepatology. 58: 949-55. PMID 23333527 DOI: 10.1016/J.Jhep.2013.01.003 |
0.656 |
|
| 2013 |
Bajaj J, Heuman D, Sanyal A, Hylemon P, Sterling R, Stravitz R, Fuchs M, Ridlon J, Daita K, Monteith P, White M, Noble N, Fisher A, Sikaroodi M, Rangwala H, et al. 192 RIFAXIMIN IMPROVES COGNITION AND ENDOTOXEMIA IN MINIMAL HEPATIC ENCEPHALOPATHY BY SHIFTING GUT MICROBIAL FUNCTIONALITY WITHOUT ALTERING THEIR ABUNDANCE Journal of Hepatology. 58: S84-S85. DOI: 10.1016/S0168-8278(13)60194-4 |
0.62 |
|
| 2012 |
Bajaj JS, Hylemon PB, Ridlon JM, Heuman DM, Daita K, White MB, Monteith P, Noble NA, Sikaroodi M, Gillevet PM. Colonic mucosal microbiome differs from stool microbiome in cirrhosis and hepatic encephalopathy and is linked to cognition and inflammation. American Journal of Physiology. Gastrointestinal and Liver Physiology. 303: G675-85. PMID 22821944 DOI: 10.1152/Ajpgi.00152.2012 |
0.63 |
|
| 2012 |
Srivastava J, Siddiq A, Emdad L, Santhekadur PK, Chen D, Gredler R, Shen XN, Robertson CL, Dumur CI, Hylemon PB, Mukhopadhyay ND, Bhere D, Shah K, Ahmad R, Giashuddin S, et al. Astrocyte elevated gene-1 promotes hepatocarcinogenesis: novel insights from a mouse model. Hepatology (Baltimore, Md.). 56: 1782-91. PMID 22689379 DOI: 10.1002/Hep.25868 |
0.317 |
|
| 2012 |
Bajaj JS, Gillevet PM, Patel NR, Ahluwalia V, Ridlon JM, Kettenmann B, Schubert CM, Sikaroodi M, Heuman DM, Crossey MM, Bell DE, Hylemon PB, Fatouros PP, Taylor-Robinson SD. A longitudinal systems biology analysis of lactulose withdrawal in hepatic encephalopathy. Metabolic Brain Disease. 27: 205-15. PMID 22527995 DOI: 10.1007/S11011-012-9303-0 |
0.604 |
|
| 2012 |
Xu L, Shen S, Ma Y, Kim JK, Rodriguez-Agudo D, Heuman DM, Hylemon PB, Pandak WM, Ren S. 25-Hydroxycholesterol-3-sulfate attenuates inflammatory response via PPARγ signaling in human THP-1 macrophages. American Journal of Physiology. Endocrinology and Metabolism. 302: E788-99. PMID 22275753 DOI: 10.1152/Ajpendo.00337.2011 |
0.334 |
|
| 2012 |
Ridlon JM, Hylemon PB. Identification and characterization of two bile acid coenzyme A transferases from Clostridium scindens, a bile acid 7α-dehydroxylating intestinal bacterium. Journal of Lipid Research. 53: 66-76. PMID 22021638 DOI: 10.1194/Jlr.M020313 |
0.69 |
|
| 2012 |
Bajaj JS, Ridlon JM, Hylemon PB, Thacker LR, Heuman DM, Smith S, Sikaroodi M, Gillevet PM. Linkage of gut microbiome with cognition in hepatic encephalopathy. American Journal of Physiology. Gastrointestinal and Liver Physiology. 302: G168-75. PMID 21940902 DOI: 10.1152/Ajpgi.00190.2011 |
0.623 |
|
| 2012 |
Studer E, Zhou X, Zhao R, Wang Y, Takabe K, Nagahashi M, Pandak WM, Dent P, Spiegel S, Shi R, Xu W, Liu X, Bohdan P, Zhang L, Zhou H, ... Hylemon PB, et al. Conjugated bile acids activate the sphingosine-1-phosphate receptor 2 in primary rodent hepatocytes. Hepatology (Baltimore, Md.). 55: 267-76. PMID 21932398 DOI: 10.1002/Hep.24681 |
0.381 |
|
| 2012 |
Srivastava J, Siddiq A, Emdad L, Santhekadur PK, Chen D, Gredler R, Shen X, Robertson CL, Stafflinger J, Subler MA, Dumur CI, Hylemon PB, Windle JJ, Fisher PB, Sarkar D. Abstract 1324: Unraveling novel functions of the oncogene Astrocyte elevated gene-1 (AEG-1) contributing to hepatocarcinogenesis employing a transgenic mouse model Cancer Research. 72: 1324-1324. DOI: 10.1158/1538-7445.Am2012-1324 |
0.328 |
|
| 2012 |
Kakiyama G, Ridlon J, Hylemon P, Pandak W, Gillevet P, Heuman D, Daita K, Bajaj J. 116 THE GUT MICROBIOME MODULATES FECAL BILE ACID PROFILE IN PATIENTS WITH CIRRHOSIS Journal of Hepatology. 56: S51. DOI: 10.1016/S0168-8278(12)60130-5 |
0.68 |
|
| 2012 |
Wang Y, Masayuki N, Takabe K, Gurley EC, Hylemon P, Pandak WM, Zhang L, Zhou H. Tu1820 Sphingosine Kinase 2 Deficiency Disrupts Hepatic Lipid Metabolism Gastroenterology. 142: S-1025. DOI: 10.1016/S0016-5085(12)63966-3 |
0.319 |
|
| 2012 |
Li Y, Zhang X, Wang G, Gurley EC, Hylemon P, Pandak WM, Zhou H. 695 18ß-Glycyrrhetinic Acid Prevents Free Fatty Acid-Induced Hepatic Lipotoxicity by Upregulating GRP78 Expression Gastroenterology. 142: S-922. DOI: 10.1016/S0016-5085(12)63578-1 |
0.389 |
|
| 2011 |
Rodriguez-Agudo D, Calderon-Dominguez M, Ren S, Marques D, Redford K, Medina-Torres MA, Hylemon P, Gil G, Pandak WM. Subcellular localization and regulation of StarD4 protein in macrophages and fibroblasts. Biochimica Et Biophysica Acta. 1811: 597-606. PMID 21767660 DOI: 10.1016/J.Bbalip.2011.06.028 |
0.342 |
|
| 2011 |
Bai Q, Xu L, Kakiyama G, Runge-Morris MA, Hylemon PB, Yin L, Pandak WM, Ren S. Sulfation of 25-hydroxycholesterol by SULT2B1b decreases cellular lipids via the LXR/SREBP-1c signaling pathway in human aortic endothelial cells. Atherosclerosis. 214: 350-6. PMID 21146170 DOI: 10.1016/J.Atherosclerosis.2010.11.021 |
0.34 |
|
| 2010 |
Xu L, Bai Q, Rodriguez-Agudo D, Hylemon PB, Heuman DM, Pandak WM, Ren S. Regulation of hepatocyte lipid metabolism and inflammatory response by 25-hydroxycholesterol and 25-hydroxycholesterol-3-sulfate. Lipids. 45: 821-32. PMID 20700770 DOI: 10.1007/S11745-010-3451-Y |
0.409 |
|
| 2010 |
Cao R, Cronk ZX, Zha W, Sun L, Wang X, Fang Y, Studer E, Zhou H, Pandak WM, Dent P, Gil G, Hylemon PB. Bile acids regulate hepatic gluconeogenic genes and farnesoid X receptor via G(alpha)i-protein-coupled receptors and the AKT pathway. Journal of Lipid Research. 51: 2234-44. PMID 20305288 DOI: 10.1194/Jlr.M004929 |
0.35 |
|
| 2010 |
Ridlon JM, Kang DJ, Hylemon PB. Isolation and characterization of a bile acid inducible 7alpha-dehydroxylating operon in Clostridium hylemonae TN271. Anaerobe. 16: 137-46. PMID 19464381 DOI: 10.1016/J.Anaerobe.2009.05.004 |
0.686 |
|
| 2010 |
Bajaj J, McPhail M, Heuman D, Bell D, Gillevet P, Sikaroodi M, Sanyal A, Sharif M, Ridlon J, Hylemon P, Taylor-Robinson S. 151 URINARY MAGNETIC RESONANCE SPECTROSCOPY IN PATIENTS WITH HEPATIC ENCEPHALOPATHY: CITRATE CORRELATES WITH ASYMMETRIC DIMETHYLARGININE AND GUT MICROBIAL SPECIES AND CAN PREDICT RECURRENCE AFTER LACTULOSE DISCONTINUATION Journal of Hepatology. 52: S67. DOI: 10.1016/S0168-8278(10)60153-5 |
0.606 |
|
| 2010 |
Xu L, Bai Q, Hylemon P, Heuman DM, Pandak WM, Ren S. 313 25-Hydroxycholesterol-3-Sulfate (25HC3S) Attenuates Hepatocyte Intracellular Lipid Levels and Inflammatory Response via LXR/Srebps and IKB/NF-kB Pathways Gastroenterology. 138: S-783. DOI: 10.1016/S0016-5085(10)63608-6 |
0.318 |
|
| 2009 |
Hylemon PB, Zhou H, Pandak WM, Ren S, Gil G, Dent P. Bile acids as regulatory molecules. Journal of Lipid Research. 50: 1509-20. PMID 19346331 DOI: 10.1194/Jlr.R900007-Jlr200 |
0.43 |
|
| 2009 |
Li Y, Zha W, Sun L, Wu X, Gurley EC, Studer E, Hylemon P, Pandak WM, Zhou H. W1242 Glycyrrhetinic Acid Prevents LPS-Induced Inflammatory Response in Macrophages and Intestinal Epithelial Cells Gastroenterology. 136: A-685. DOI: 10.1016/S0016-5085(09)63155-3 |
0.323 |
|
| 2008 |
Ma Y, Xu L, Rodriguez-Agudo D, Li X, Heuman DM, Hylemon PB, Pandak WM, Ren S. 25-Hydroxycholesterol-3-sulfate regulates macrophage lipid metabolism via the LXR/SREBP-1 signaling pathway. American Journal of Physiology. Endocrinology and Metabolism. 295: E1369-79. PMID 18854425 DOI: 10.1152/Ajpendo.90555.2008 |
0.401 |
|
| 2008 |
Wu X, Zhang L, Gurley E, Studer E, Shang J, Wang T, Wang C, Yan M, Jiang Z, Hylemon PB, Sanyal AJ, Pandak WM, Zhou H. Prevention of free fatty acid-induced hepatic lipotoxicity by 18beta-glycyrrhetinic acid through lysosomal and mitochondrial pathways. Hepatology (Baltimore, Md.). 47: 1905-15. PMID 18452148 DOI: 10.1002/Hep.22239 |
0.394 |
|
| 2008 |
Rodriguez-Agudo D, Ren S, Wong E, Marques D, Redford K, Gil G, Hylemon P, Pandak WM. Intracellular cholesterol transporter StarD4 binds free cholesterol and increases cholesteryl ester formation. Journal of Lipid Research. 49: 1409-19. PMID 18403318 DOI: 10.1194/Jlr.M700537-Jlr200 |
0.313 |
|
| 2008 |
Liang G, Li X, Chen L, Yang S, Wu X, Studer E, Gurley E, Hylemon PB, Ye F, Li Y, Zhou H. Synthesis and anti-inflammatory activities of mono-carbonyl analogues of curcumin. Bioorganic & Medicinal Chemistry Letters. 18: 1525-9. PMID 18234497 DOI: 10.1016/J.Bmcl.2007.12.068 |
0.314 |
|
| 2008 |
Kang DJ, Ridlon JM, Moore DR, Barnes S, Hylemon PB. Clostridium scindens baiCD and baiH genes encode stereo-specific 7alpha/7beta-hydroxy-3-oxo-delta4-cholenoic acid oxidoreductases. Biochimica Et Biophysica Acta. 1781: 16-25. PMID 18047844 DOI: 10.1016/J.Bbalip.2007.10.008 |
0.672 |
|
| 2008 |
Ren S, Li X, Ma Y, Rodriguez-Agudo D, Gil G, Hylemon P, Heuman DM, Pandak WM. 168 Regulation of Hepatocyte Lipid Metabolism By 25-Hydroxycholesterol-3-Sulfate (25hc3s) Is Mediated Via the LXR / Srebp-1 Signaling Pathway Gastroenterology. 134: A-756-A-757. DOI: 10.1016/S0016-5085(08)63533-7 |
0.325 |
|
| 2008 |
Wu X, Zhang L, Shang J, Gurley EC, Studer E, Wang X, Hylemon P, Pandak WM, Sanyal AJ, Zhou H. 112 18β-Glycyrrhetinic Acid Prevents Free Fatty Acids/High Fat Diet-Induced Hepatic Toxicity By Inhibiting Cathepsin B Expression and Enzyme Activities Gastroenterology. 134: A-754-A-755. DOI: 10.1016/S0016-5085(08)63524-6 |
0.382 |
|
| 2007 |
Li X, Pandak WM, Erickson SK, Ma Y, Yin L, Hylemon P, Ren S. Biosynthesis of the regulatory oxysterol, 5-cholesten-3beta,25-diol 3-sulfate, in hepatocytes. Journal of Lipid Research. 48: 2587-96. PMID 17890683 DOI: 10.1194/Jlr.M700301-Jlr200 |
0.333 |
|
| 2007 |
Ren S, Li X, Rodriguez-Agudo D, Gil G, Hylemon P, Pandak WM. Sulfated oxysterol, 25HC3S, is a potent regulator of lipid metabolism in human hepatocytes. Biochemical and Biophysical Research Communications. 360: 802-8. PMID 17624300 DOI: 10.1016/J.Bbrc.2007.06.143 |
0.39 |
|
| 2007 |
Xu Z, Tavares-Sanchez OL, Li Q, Fernando J, Rodriguez CM, Studer EJ, Pandak WM, Hylemon PB, Gil G. Activation of bile acid biosynthesis by the p38 mitogen-activated protein kinase (MAPK): hepatocyte nuclear factor-4alpha phosphorylation by the p38 MAPK is required for cholesterol 7alpha-hydroxylase expression. The Journal of Biological Chemistry. 282: 24607-14. PMID 17603092 DOI: 10.1074/Jbc.M611481200 |
0.341 |
|
| 2006 |
Zhou H, Gurley EC, Jarujaron S, Ding H, Fang Y, Xu Z, Pandak WM, Hylemon PB. HIV protease inhibitors activate the unfolded protein response and disrupt lipid metabolism in primary hepatocytes. American Journal of Physiology. Gastrointestinal and Liver Physiology. 291: G1071-80. PMID 16861219 DOI: 10.1152/Ajpgi.00182.2006 |
0.326 |
|
| 2006 |
Ridlon JM, Hylemon PB. A potential role for resistant starch fermentation in modulating colonic bacterial metabolism and colon cancer risk. Cancer Biology & Therapy. 5: 273-4. PMID 16627972 DOI: 10.4161/Cbt.5.3.2728 |
0.616 |
|
| 2006 |
Rodriguez-Agudo D, Ren S, Hylemon PB, Montañez R, Redford K, Natarajan R, Medina MA, Gil G, Pandak WM. Localization of StarD5 cholesterol binding protein. Journal of Lipid Research. 47: 1168-75. PMID 16534142 DOI: 10.1194/Jlr.M500447-Jlr200 |
0.327 |
|
| 2006 |
Ren S, Hylemon P, Zhang ZP, Rodriguez-Agudo D, Marques D, Li X, Zhou H, Gil G, Pandak WM. Identification of a novel sulfonated oxysterol, 5-cholesten-3beta,25-diol 3-sulfonate, in hepatocyte nuclei and mitochondria. Journal of Lipid Research. 47: 1081-90. PMID 16505492 DOI: 10.1194/Jlr.M600019-Jlr200 |
0.359 |
|
| 2006 |
Ridlon JM, Kang DJ, Hylemon PB. Bile salt biotransformations by human intestinal bacteria. Journal of Lipid Research. 47: 241-59. PMID 16299351 DOI: 10.1194/Jlr.R500013-Jlr200 |
0.691 |
|
| 2005 |
Hall EA, Ren S, Hylemon PB, Redford K, del Castillo A, Gil G, Pandak WM. Mitochondrial cholesterol transport: a possible target in the management of hyperlipidemia. Lipids. 40: 1237-44. PMID 16477808 DOI: 10.1007/S11745-005-1491-0 |
0.352 |
|
| 2005 |
Ridlon JM, McGarr SE, Hylemon PB. Development of methods for the detection and quantification of 7alpha-dehydroxylating clostridia, Desulfovibrio vulgaris, Methanobrevibacter smithii, and Lactobacillus plantarum in human feces. Clinica Chimica Acta; International Journal of Clinical Chemistry. 357: 55-64. PMID 15963794 DOI: 10.1016/J.Cccn.2005.02.004 |
0.665 |
|
| 2005 |
Hall EA, Ren S, Hylemon PB, Rodriguez-Agudo D, Redford K, Marques D, Kang D, Gil G, Pandak WM. Detection of the steroidogenic acute regulatory protein, StAR, in human liver cells. Biochimica Et Biophysica Acta. 1733: 111-9. PMID 15863358 DOI: 10.1016/J.Bbalip.2005.01.004 |
0.379 |
|
| 2005 |
Langston TB, Hylemon PB, Grogan WM. Over-expression of hepatic neutral cytosolic cholesteryl ester hydrolase in mice increases free cholesterol and reduces expression of HMG-CoAR, CYP27, and CYP7A1. Lipids. 40: 31-8. PMID 15825828 DOI: 10.1007/S11745-005-1357-5 |
0.337 |
|
| 2005 |
McGarr SE, Ridlon JM, Hylemon PB. Diet, anaerobic bacterial metabolism, and colon cancer: a review of the literature. Journal of Clinical Gastroenterology. 39: 98-109. PMID 15681903 |
0.619 |
|
| 2004 |
Ren S, Hylemon PB, Marques D, Gurley E, Bodhan P, Hall E, Redford K, Gil G, Pandak WM. Overexpression of cholesterol transporter StAR increases in vivo rates of bile acid synthesis in the rat and mouse. Hepatology (Baltimore, Md.). 40: 910-7. PMID 15382124 DOI: 10.1002/Hep.1840400421 |
0.359 |
|
| 2004 |
Ren S, Hylemon P, Marques D, Hall E, Redford K, Gil G, Pandak WM. Effect of increasing the expression of cholesterol transporters (StAR, MLN64, and SCP-2) on bile acid synthesis. Journal of Lipid Research. 45: 2123-31. PMID 15342684 DOI: 10.1194/Jlr.M400233-Jlr200 |
0.408 |
|
| 2004 |
Williams K, Rao YP, Natarajan R, Pandak WM, Hylemon PB. Indinavir alters sterol and fatty acid homeostatic mechanisms in primary rat hepatocytes by increasing levels of activated sterol regulatory element-binding proteins and decreasing cholesterol 7alpha-hydroxylase mRNA levels. Biochemical Pharmacology. 67: 255-67. PMID 14698038 DOI: 10.1016/J.Bcp.2003.08.044 |
0.382 |
|
| 2004 |
Gupta S, Natarajan R, Payne SG, Studer EJ, Spiegel S, Dent P, Hylemon PB. Deoxycholic acid activates the c-Jun N-terminal kinase pathway via FAS receptor activation in primary hepatocytes. Role of acidic sphingomyelinase-mediated ceramide generation in FAS receptor activation. The Journal of Biological Chemistry. 279: 5821-8. PMID 14660582 DOI: 10.1074/Jbc.M310979200 |
0.369 |
|
| 2004 |
Fang Y, Han SI, Mitchell C, Gupta S, Studer E, Grant S, Hylemon PB, Dent P. Bile acids induce mitochondrial ROS, which promote activation of receptor tyrosine kinases and signaling pathways in rat hepatocytes Hepatology. 40: 961-971. DOI: 10.1002/Hep.1840400427 |
0.326 |
|
| 2003 |
Ren S, Marques D, Redford K, Hylemon PB, Gil G, Vlahcevic ZR, Pandak WM. Regulation of oxysterol 7alpha-hydroxylase (CYP7B1) in the rat. Metabolism: Clinical and Experimental. 52: 636-42. PMID 12759897 DOI: 10.1053/Meta.2003.50106 |
0.41 |
|
| 2003 |
Wells JE, Williams KB, Whitehead TR, Heuman DM, Hylemon PB. Development and application of a polymerase chain reaction assay for the detection and enumeration of bile acid 7alpha-dehydroxylating bacteria in human feces. Clinica Chimica Acta; International Journal of Clinical Chemistry. 331: 127-34. PMID 12691873 DOI: 10.1016/S0009-8981(03)00115-3 |
0.419 |
|
| 2003 |
Rao Y, Williams K, Pandak WM, Hylemon PB. Mechanism for dysregulation of hepatic lipid metabolism by indinavir: Inceasing level of activated sterol regulatory element-bindin protein (SREBP) and decreasing cholesterol-7 alpha-hydroxylase mRNA levels Gastroenterology. 124: A727. DOI: 10.1016/S0016-5085(03)83674-0 |
0.344 |
|
| 2003 |
Gupta S, Studer EJ, Payne SG, Dent P, Hylemon PB. Deoxycholic acid activates the c-Jun N-terminal kinase (JNK) pathway via activation of the FAS receptor Gastroenterology. 124: A727. DOI: 10.1016/S0016-5085(03)83673-9 |
0.301 |
|
| 2003 |
Pandak WM, Ren S, Marques D, Redford K, Gurley E, Bodham P, Hall E, Gil G, Hylemon P. Overexpression of the mitochondrial cholesterol transport protein, StARD1, increases in vivo rates of bile acid synthesis in the rat and the mouse Gastroenterology. 124: A698. DOI: 10.1016/S0016-5085(03)83530-8 |
0.323 |
|
| 2002 |
Pandak WM, Ren S, Marques D, Hall E, Redford K, Mallonee D, Bohdan P, Heuman D, Gil G, Hylemon P. Transport of cholesterol into mitochondria is rate-limiting for bile acid synthesis via the alternative pathway in primary rat hepatocytes. The Journal of Biological Chemistry. 277: 48158-64. PMID 12368294 DOI: 10.1074/Jbc.M205244200 |
0.404 |
|
| 2002 |
Gerbod-Giannone MC, Del Castillo-Olivares A, Janciauskiene S, Gil G, Hylemon PB. Suppression of cholesterol 7alpha-hydroxylase transcription and bile acid synthesis by an alpha1-antitrypsin peptide via interaction with alpha1-fetoprotein transcription factor. The Journal of Biological Chemistry. 277: 42973-80. PMID 12223476 DOI: 10.1074/Jbc.M205089200 |
0.752 |
|
| 2002 |
Gupta S, Pandak WM, Hylemon PB. LXR alpha is the dominant regulator of CYP7A1 transcription. Biochemical and Biophysical Research Communications. 293: 338-43. PMID 12054605 DOI: 10.1016/S0006-291X(02)00229-2 |
0.379 |
|
| 2002 |
Pandak WM, Hylemon PB, Ren S, Marques D, Gil G, Redford K, Mallonee D, Vlahcevic ZR. Regulation of oxysterol 7alpha-hydroxylase (CYP7B1) in primary cultures of rat hepatocytes. Hepatology (Baltimore, Md.). 35: 1400-8. PMID 12029625 DOI: 10.1053/Jhep.2002.33200 |
0.43 |
|
| 2002 |
Rao YP, Studer EJ, Stravitz RT, Gupta S, Qiao L, Dent P, Hylemon PB. Activation of the Raf-1/MEK/ERK cascade by bile acids occurs via the epidermal growth factor receptor in primary rat hepatocytes. Hepatology (Baltimore, Md.). 35: 307-14. PMID 11826403 DOI: 10.1053/Jhep.2002.31104 |
0.343 |
|
| 2001 |
Thomas LA, Veysey MJ, French G, Hylemon PB, Murphy GM, Dowling RH. Bile acid metabolism by fresh human colonic contents: a comparison of caecal versus faecal samples. Gut. 49: 835-42. PMID 11709519 DOI: 10.1136/Gut.49.6.835 |
0.326 |
|
| 2001 |
Pandak WM, Schwarz C, Hylemon PB, Mallonee D, Valerie K, Heuman DM, Fisher RA, Redford K, Vlahcevic ZR. Effects of CYP7A1 overexpression on cholesterol and bile acid homeostasis. American Journal of Physiology. Gastrointestinal and Liver Physiology. 281: G878-89. PMID 11557507 DOI: 10.1152/Ajpgi.2001.281.4.G878 |
0.406 |
|
| 2001 |
Hall E, Hylemon P, Vlahcevic Z, Mallonee D, Valerie K, Avadhani N, Pandak W. Overexpression of CYP27 in hepatic and extrahepatic cells: role in the regulation of cholesterol homeostasis. American Journal of Physiology. Gastrointestinal and Liver Physiology. 281: G293-301. PMID 11408283 DOI: 10.1152/Ajpgi.2001.281.1.G293 |
0.367 |
|
| 2001 |
Pandak WM, Bohdan P, Franklund C, Mallonee DH, Eggertsen G, Björkhem I, Gil G, Vlahcevic ZR, Hylemon PB. Expression of sterol 12α-hydroxylase alters bile acid pool composition in primary rat hepatocytes and in vivo Gastroenterology. 120: 1801-1809. PMID 11375960 DOI: 10.1053/Gast.2001.24833 |
0.375 |
|
| 2001 |
Pandak WM, Hylemon PB, Bohdan P, Bjorkhem I, Eggertsen G, Vlahcevic ZR. Overexpression of sterol 12α-hydroxylase (CYP8b1): Effect on rates of cholic acid (CA) synthesis and alteration in bile acid pool composition Gastroenterology. 120: A1. DOI: 10.1016/S0016-5085(08)80003-0 |
0.356 |
|
| 2000 |
Gupta S, Todd Stravitz R, Pandak WM, Müller M, Reno Vlahcevic Z, Hylemon PB. Regulation of multidrug resistance 2 P-glycoprotein expression by bile salts in rats and in primary cultures of rat hepatocytes Hepatology. 32: 341-347. PMID 10915741 DOI: 10.1053/Jhep.2000.9605 |
0.33 |
|
| 2000 |
Vlahcevic ZR, Eggertsen G, Björkhem I, Hylemon PB, Redford K, Pandak WM. Regulation of sterol 12α-hydroxylase and cholic acid biosynthesis in the rat Gastroenterology. 118: 599-607. PMID 10702212 DOI: 10.1016/S0016-5085(00)70267-8 |
0.333 |
|
| 2000 |
Wells JE, Hylemon PB. Identification and characterization of a bile acid 7α-dehydroxylation operon in Clostridium sp. strain TO-931, a highly active 7α-dehydroxylating strain isolated from human feces Applied and Environmental Microbiology. 66: 1107-1113. PMID 10698778 DOI: 10.1128/Aem.66.3.1107-1113.2000 |
0.337 |
|
| 2000 |
Wells JE, Berr F, Thomas LA, Dowling RH, Hylemon PB. Isolation and characterization of cholic acid 7alpha-dehydroxylating fecal bacteria from cholesterol gallstone patients. Journal of Hepatology. 32: 4-10. PMID 10673060 DOI: 10.1016/S0168-8278(00)80183-X |
0.413 |
|
| 2000 |
Hall EA, Vlahcevic ZR, Hylemon PB, Mallonee D, Pandak WM. Sterol 27-hydroxylase is a tissue specific regulator of cholesterol and bile acid synthesis Gastroenterology. 118: A999. DOI: 10.1016/S0016-5085(00)86144-2 |
0.365 |
|
| 2000 |
Pandak WM, Lijun Z, Hylemon PB, Vlahcevic ZR. Regulation of oxysterol 7A-hydroxylase (CYP7b1) in primary cultures of rat hepatocytes by bile acids (BA), cholesterol (chol), cAMP and phorbol ester Gastroenterology. 118: A998. DOI: 10.1016/S0016-5085(00)86140-5 |
0.339 |
|
| 2000 |
Gupta S, Stravitz RT, Dent P, Vlahcevic ZR, Hylemon PB. Bile acid induced signal transductive pathways involved in regulation of cholesterol 7a-hydroxylase(CYP7a1) transcription Gastroenterology. 118: A2. DOI: 10.1016/S0016-5085(00)82073-9 |
0.412 |
|
| 1999 |
Rao YP, Vlahcevic ZR, Stravitz RT, Mallonee DH, Mullick J, Avadhani NG, Hylemon PB. Down-regulation of the rat hepatic sterol 27-hydroxylasegene by bile acids in transfected primary hepatocytes: Possible role of hepatic nuclear factor 1α Journal of Steroid Biochemistry and Molecular Biology. 70: 1-14. PMID 10528998 DOI: 10.1016/S0960-0760(99)00099-0 |
0.371 |
|
| 1998 |
Hylemon PB, Harder J. Biotransformation of monoterpenes, bile acids, and other isoprenoids in anaerobic ecosystems Fems Microbiology Reviews. 22: 475-488. PMID 9990726 DOI: 10.1016/S0168-6445(98)00027-8 |
0.304 |
|
| 1998 |
Ghosh S, Natarajan R, Pandak WM, Hylemon PB, Grogan WM. Regulation of hepatic neutral cholesteryl ester hydrolase by hormones and changes in cholesterol flux. The American Journal of Physiology. 274: G662-8. PMID 9575847 DOI: 10.1152/Ajpgi.1998.274.4.G662 |
0.338 |
|
| 1998 |
Coleman JP, Kirby LC, Setchell KD, Hylemon PB, Pandak M, Heuman DM, Vlahcevic ZR. Metabolic fate and hepatocyte toxicity of reverse amide analogs of conjugated ursodeoxycholate in the rat. The Journal of Steroid Biochemistry and Molecular Biology. 64: 91-101. PMID 9569014 DOI: 10.1016/S0960-0760(97)00138-6 |
0.407 |
|
| 1997 |
Vlahcevic ZR, Stravitz RT, Heuman DM, Hylemon PB, Pandak WM. Quantitative estimations of the contribution of different bile acid pathways to total bile acid synthesis in the rat Gastroenterology. 113: 1949-1957. PMID 9394735 DOI: 10.1016/S0016-5085(97)70015-5 |
0.426 |
|
| 1997 |
Doerner KC, Takamine F, LaVoie CP, Mallonee DH, Hylemon PB. Assessment of fecal bacteria with bile acid 7α-dehydroxylating activity for the presence of bai-like genes Applied and Environmental Microbiology. 63: 1185-1188. PMID 9055436 DOI: 10.1128/Aem.63.3.1185-1188.1997 |
0.338 |
|
| 1996 |
Mallonee DH, Hylemon PB. Sequencing and expression of a gene encoding a bile acid transporter from Eubacterium sp. strain VPI 12708 Journal of Bacteriology. 178: 7053-7058. PMID 8955384 DOI: 10.1128/Jb.178.24.7053-7058.1996 |
0.382 |
|
| 1996 |
Vlahcevic ZR, Jairath SK, Heuman DM, Stravitz RT, Hylemon PB, Avadhani NG, Pandak WM. Transcriptional regulation of hepatic sterol 27-hydroxylase by bile acids American Journal of Physiology - Gastrointestinal and Liver Physiology. 270. PMID 8928794 DOI: 10.1152/Ajpgi.1996.270.4.G646 |
0.345 |
|
| 1996 |
Stravitz RT, Rao YP, Vlahcevic ZR, Gurley EC, Jarvis WD, Hylemon PB, Holmes H. Hepatocellular protein kinase C activation by bile acids: Implications for regulation of cholesterol 7α-hydroxylase American Journal of Physiology - Gastrointestinal and Liver Physiology. 271. PMID 8770045 DOI: 10.1152/Ajpgi.1996.271.2.G293 |
0.37 |
|
| 1996 |
Stravitz RT, Vlahcevic ZR, Russell TL, Heizer ML, Avadhani NG, Hylemon PB. Regulation of sterol 27-hydroxylase and an alternative pathway of bile acid biosynthesis in primary cultures of rat hepatocytes. The Journal of Steroid Biochemistry and Molecular Biology. 57: 337-47. PMID 8639470 DOI: 10.1016/0960-0760(95)00282-0 |
0.426 |
|
| 1995 |
Pandak WM, Heuman DM, Hylemon PB, Chiang JYL, Reno Vlahcevic Z. Failure of intravenous infusion of taurocholate to down-regulate cholesterol 7α-hydroxylase in rats with biliary fistulas Gastroenterology. 108: 533-544. PMID 7835596 DOI: 10.1016/0016-5085(95)90083-7 |
0.379 |
|
| 1995 |
Mallonee DH, Lijewski MA, Hylemon PB. Expression in Escherichia coli and characterization of a bile acid-inducible 3α-hydroxysteroid dehydrogenase from Eubacterium sp. strain VPI 12708 Current Microbiology. 30: 259-263. PMID 7766153 DOI: 10.1007/Bf00295498 |
0.381 |
|
| 1995 |
Baron SF, Hylemon PB. Expression of the bile acid-inducible NADH:flavin oxidoreductase gene of Eubacterium sp. VPI 12708 in Escherichia coli Biochimica Et Biophysica Acta (Bba)/Protein Structure and Molecular. 1249: 145-154. PMID 7599167 DOI: 10.1016/0167-4838(95)00034-R |
0.403 |
|
| 1993 |
Franklund CV, Baron SF, Hylemon PB. Characterization of the baiH gene encoding a bile acid-inducible NADH:flavin oxidoreductase from Eubacterium sp. strain VPI 12708 Journal of Bacteriology. 175: 3002-3012. PMID 8491719 DOI: 10.1128/Jb.175.10.3002-3012.1993 |
0.344 |
|
| 1992 |
Mallonee DH, Adams JL, Hylemon PB. The bile acid-inducible baiB gene from Eubacterium sp. strain VPI 12708 encodes a bile acid-coenzyme A ligase Journal of Bacteriology. 174: 2065-2071. PMID 1551828 DOI: 10.1128/Jb.174.7.2065-2071.1992 |
0.422 |
|
| 1992 |
Vlahcevic ZR, Pandak WM, Heuman DM, Hylemon PB. Function and regulation of hydroxylases involved in the bile acid biosynthesis pathways Seminars in Liver Disease. 12: 403-419. PMID 1465624 |
0.317 |
|
| 1992 |
Heuman DM, Vlahcevic ZR, Pandak WM, Hylemon PB, Kim YS, Lillienau J, Hofmann AF. Effect of cholylsarcosine on hepatic cholesterol and bile acid synthesis and bile secretion in rats Gastroenterology. 103: 1641-1648. PMID 1385253 DOI: 10.1016/0016-5085(92)91190-F |
0.407 |
|
| 1991 |
Hylemon PB, Raynor L, Bohdan PM, Reno Vlahcevic Z. High-performance liquid chromatography assay for 3β-hydroxy-Δ5-C27-steroid oxidoreductase activity in rat liver microsomes Analytical Biochemistry. 193: 256-259. PMID 1872471 DOI: 10.1016/0003-2697(91)90018-O |
0.333 |
|
| 1991 |
Baron SF, Franklund CV, Hylemon PB. Cloning, sequencing, and expression of the gene coding for bile acid 7α-hydroxysteroid dehydrogenase from Eubacterium sp. strain VPI 12708 Journal of Bacteriology. 173: 4558-4569. PMID 1856160 DOI: 10.1128/Jb.173.15.4558-4569.1991 |
0.328 |
|
| 1991 |
Vlahcevic ZR, Heuman DM, Hylemon PB. Regulation of bile acid synthesis Hepatology. 13: 590-600. DOI: 10.1002/Hep.1840130331 |
0.337 |
|
| 1990 |
Gopal-Srivastava R, Mallonee DH, White WB, Hylemon PB. Multiple copies of a bile acid-inducible gene in Eubacterium sp. strain VPI 12708 Journal of Bacteriology. 172: 4420-4426. PMID 2376563 DOI: 10.1128/Jb.172.8.4420-4426.1990 |
0.3 |
|
| 1990 |
Hylemon PB, Bohdan PM, Sirica AE, Heuman DM, Vlahcevic ZR. Cholesterol and bile acid metabolism in cultures of primary rat bile ductular epithelial cells Hepatology. 11: 982-988. PMID 2365295 DOI: 10.1002/hep.1840110612 |
0.335 |
|
| 1990 |
Pandak WM, Heuman DM, Hylemon PB, Vlahcevic ZR. Regulation of bile acid synthesis. IV. Interrelationship between cholesterol and bile acid biosynthesis pathways Journal of Lipid Research. 31: 79-90. PMID 2313206 |
0.306 |
|
| 1989 |
Heuman DM, Hylemon PB, Vlahcevic ZR. Regulation of bile acid synthesis. III. Correlation between biliary bile salt hydrophobicity index and the activities of enzymes regulating cholesterol and bile acid synthesis in the rat Journal of Lipid Research. 30: 1161-1171. PMID 2769071 DOI: 10.1016/0270-9139(91)90317-O |
0.306 |
|
| 1988 |
Heuman DM, Vlahcevic ZR, Bailey ML, Hylemon PB. Regulation of bile acid synthesis. II. Effect of bile acid feeding on enzymes regulating hepatic cholesterol and bile acid synthesis in the rat. Hepatology (Baltimore, Md.). 8: 892-7. PMID 3391517 |
0.343 |
|
| 1988 |
Heuman DM, Hernandez CR, Hylemon PB, Kubaska WM, Hartman C, Vlahcevic ZR. Regulation of bile acid synthesis. I. Effects of conjugated ursodeoxycholate and cholate on bile acid synthesis in chronic bile fistula rat Hepatology. 8: 358-365. PMID 3356417 |
0.325 |
|
| 1987 |
Kubaska WM, Gurley EC, Hylemon PB, Heuman DM, Mosbach EH, Vlahcevic ZR. Effects of ursodeoxycholic acid, analogues of ursodeoxycholic acid and combination of bile acids on bile acid synthesis in cultured rat hepatocytes Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 920: 195-204. PMID 3607077 DOI: 10.1016/0005-2760(87)90095-6 |
0.429 |
|
| 1987 |
Coleman JP, White WB, Hylemon PB. Molecular cloning of bile acid 7-dehydroxylase from Eubacterium sp. strain VPI 12708 Journal of Bacteriology. 169: 1516-1521. PMID 3549693 DOI: 10.1128/Jb.169.4.1516-1521.1987 |
0.354 |
|
| 1985 |
Kubaska WM, Gurley EC, Hylemon PB, Guzelian PS, Vlahcevic ZR. Absence of negative feedback control of bile acid biosynthesis in cultured rat hepatocytes Journal of Biological Chemistry. 260: 13459-13463. PMID 4055743 |
0.303 |
|
| 1985 |
Hylemon PB. Chapter 12 Metabolism of bile acids in intestinal microflora New Comprehensive Biochemistry. 12: 331-343. DOI: 10.1016/S0167-7306(08)60688-2 |
0.446 |
|
| 1984 |
Whitehead TR, Vlahcevic ZR, Beg ZH, Hylemon PB. Characterization of active and inactive forms of rat hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase Archives of Biochemistry and Biophysics. 230: 483-491. PMID 6712250 DOI: 10.1016/0003-9861(84)90428-4 |
0.311 |
|
| 1984 |
Hylemon PB, Moody DP, Cohen BI, Une M, Mosbach EH. Effect of bile acid analogs on 7α-dehydroxylase activity in eubacterium Sp. V.P.I. 12708 Steroids. 44: 329-336. PMID 6545070 DOI: 10.1016/S0039-128X(84)80025-2 |
0.35 |
|
| 1983 |
Hylemon PB, Fricke RJ, Kubaska WM, Cohen BI, Mosbach EH. Metabolism of bile acid oxazoline derivatives by hepatocyte monolayer cultures and intestinal anaerobic bacteria Steroids. 42: 105-114. PMID 6673175 DOI: 10.1016/S0039-128X(83)90132-0 |
0.427 |
|
| 1980 |
A B, Lipsky WRL, Fricke RJ, Hylemon PB. Bile acid induction specificity of 7α-dehydroxylase activity in an intestinal Eubacterium species Steroids. 35: 103-109. PMID 7376208 DOI: 10.1016/0039-128X(80)90115-4 |
0.391 |
|
| 1980 |
Lipsky RH, Hylemon PB. Characterization of a NADH:flavin oxidoreductase induced by cholic acid in a 7 alpha-dehydroxylating intestinal Eubacterium species. Biochimica Et Biophysica Acta. 612: 328-36. PMID 7370273 DOI: 10.1016/0005-2744(80)90115-1 |
0.329 |
|
| 1977 |
Sherrod JA, Hylemon PB. Partial purification and characterization of NAD-dependent 7α-hydroxysteroid dehydrogenase from Bacteroides thetaiotaomicron Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 486: 351-358. PMID 189820 DOI: 10.1016/0005-2760(77)90031-5 |
0.391 |
|
| 1976 |
Hylemon PB, Stellwag EJ. Bile acid biotransformation rates of selected gram-positive and gram-negative intestinal anaerobic bacteria Biochemical and Biophysical Research Communications. 69: 1088-1094. PMID 1275920 DOI: 10.1016/0006-291X(76)90484-8 |
0.339 |
|
| 1976 |
Stellwag EJ, Hylemon PB. Purification and characterization of bile salt hydrolase from Bacteroides fragilis subsp. fragilis Bba - Enzymology. 452: 165-176. PMID 10993 DOI: 10.1016/0005-2744(76)90068-1 |
0.328 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2016 |
Jiao C, Shi R, Hylemon P, Zhou H. Tu1306 Taurocholic Acid Promotes Gastric Adenocarcinoma Cell Proliferation via Activation of Sphingosine 1-Phosphate Receptor 2 Gastroenterology. 150: S870. DOI: 10.1016/S0016-5085(16)32932-8 |
0.299 |
|
| 1980 |
Hylemon PB, Cacciapuoti AF, White BA, Whitehead TR, Fricke RJ. 7α-Dehydroxylation of cholic acid by cell extracts of Eubacterium species V.P.I. 12708 American Journal of Clinical Nutrition. 33: 2507-2510. PMID 7435421 DOI: 10.1093/Ajcn/33.11.2507 |
0.299 |
|
| 2020 |
Wu J, Wang Y, Ge P, Tai Y, Zhang Y, Zhao D, Wang X, Gurley E, Hylemon P, Campos G, Zhou H. 453 HEPATIC SPHINGOSINE KINASE 2 PROTECTS AGAINST BILE DUCT LIGATION-INDUCED CHOLESTATIC LIVER INJURY Gastroenterology. 158: S-1277. DOI: 10.1016/S0016-5085(20)33854-3 |
0.299 |
|
| 1989 |
Hylemon PB, Studer EJ, Pandak WM, Heuman DM, Vlahcevic ZR, Chiang JYL. Simultaneous measurement of cholesterol 7α-hydroxylase activity by reverse-phase high-performance liquid chromatography using both endogenous and exogenous [4-14C]cholesterol as substrate Analytical Biochemistry. 182: 212-216. PMID 2610336 DOI: 10.1016/0003-2697(89)90581-2 |
0.298 |
|
| 2017 |
Li X, Liu R, Yang J, Sun L, Zhang L, Jiang Z, Puri P, Gurley EC, Lai G, Tang Y, Huang Z, Pandak WM, Hylemon PB, Zhou H. The role of LncRNA H19 in gender disparity of cholestatic liver injury in Mdr2(-/-) mice. Hepatology (Baltimore, Md.). PMID 28271527 DOI: 10.1002/Hep.29145 |
0.298 |
|
| 2009 |
Chen L, Jarujaron S, Wu X, Sun L, Zha W, Liang G, Wang X, Gurley EC, Studer EJ, Hylemon PB, Pandak WM, Zhang L, Wang G, Li X, Dent P, et al. HIV protease inhibitor lopinavir-induced TNF-alpha and IL-6 expression is coupled to the unfolded protein response and ERK signaling pathways in macrophages. Biochemical Pharmacology. 78: 70-7. PMID 19447225 DOI: 10.1016/J.Bcp.2009.03.022 |
0.298 |
|
| 1978 |
Harris JN, Hylemon PB. Partial purification and characterization of NADP-dependent 12α-hydroxysteroid dehydrogenase from clostridium leptum Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 528: 148-157. PMID 23170 DOI: 10.1016/0005-2760(78)90060-7 |
0.297 |
|
| 1999 |
Ye HQ, Mallonee DH, Wells JE, Björkhem I, Hylemon PB. The bile acid-inducible baiF gene from Eubacterium sp. strain VPI 12708 encodes a bile acid-coenzyme A hydrolase Journal of Lipid Research. 40: 17-23. PMID 9869646 |
0.296 |
|
| 2007 |
Zhou H, Jarujaron S, Gurley EC, Chen L, Ding H, Studer E, Pandak WM, Hu W, Zou T, Wang JY, Hylemon PB. HIV protease inhibitors increase TNF-alpha and IL-6 expression in macrophages: involvement of the RNA-binding protein HuR. Atherosclerosis. 195: e134-43. PMID 17531241 DOI: 10.1016/J.Atherosclerosis.2007.04.008 |
0.296 |
|
| 2005 |
Rodriguez-Agudo D, Ren S, Hylemon PB, Redford K, Natarajan R, Del Castillo A, Gil G, Pandak WM. Human StarD5, a cytosolic StAR-related lipid binding protein. Journal of Lipid Research. 46: 1615-23. PMID 15897605 DOI: 10.1194/Jlr.M400501-Jlr200 |
0.296 |
|
| 2007 |
Ren S, Li X, Rodriguez‐Agudo D, Chen K, Hylemon P, Pandak WM. The Nuclear Oxysterol, 5‐Cholesten‐3β, 25‐Diol 3‐Sulfate, Decreases Cholesterol Biosynthesis by Inhibiting Expression of HMG CoA Reductase in HepG2 Cells The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A454-C |
0.296 |
|
| 2020 |
Zhang Y, Yang W, Wang Y, Liu R, Li X, Zhao D, Wu J, Tai Y, Ge P, Wang X, Gurley EC, Hylemon PB, Zhou H. Sphingosine kinase 2 plays a critical role in bile acid‐induced cholestatic liver injury
via
regulating miR‐155 and macrophage activation The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.07289 |
0.294 |
|
| 2016 |
Kang D, Balfour Sartor R, Betrapally N, Nittono H, Herzog J, Hylemon P, SIkaroodi M, Gillevet P, Carroll I, Kakiyama G, Zhou H, Yang J, Jiao C, Fan S, Fiehn O, et al. The Beneficial Impact of Rifaximin on Systemic and Intestinal Inflammation and Ammonia Occurs even without Microbiota: More than an Antibiotic Journal of Hepatology. 64: S447. DOI: 10.1016/S0168-8278(16)00741-8 |
0.294 |
|
| 2016 |
Kang D, Sartor RB, Kakiyama G, Betrapally N, Herzog J, Nittono H, Hylemon P, Zhou H, Carroll I, Yang J, Gillevet PM, Jiao C, Takei H, Fan S, Fiehn O, et al. 280 The Beneficial Impact of Rifaximin on Systemic and Intestinal Inflammation and Ammonia Occurs Even Without Microbiota: More Than an Antibiotic Gastroenterology. 150: S1022-S1023. DOI: 10.1016/S0016-5085(16)33464-3 |
0.294 |
|
| 2013 |
Wang Y, Zhang L, Wu X, Gurley EC, Kennedy E, Hylemon PB, Pandak WM, Sanyal AJ, Zhou H. The role of CCAAT enhancer-binding protein homologous protein in human immunodeficiency virus protease-inhibitor-induced hepatic lipotoxicity in mice. Hepatology (Baltimore, Md.). 57: 1005-16. PMID 23080229 DOI: 10.1002/Hep.26107 |
0.291 |
|
| 2016 |
Ahluwalia V, Betrapally NS, Hylemon PB, White MB, Gillevet PM, Unser AB, Fagan A, Daita K, Heuman DM, Zhou H, Sikaroodi M, Bajaj JS. Impaired Gut-Liver-Brain Axis in Patients with Cirrhosis. Scientific Reports. 6: 26800. PMID 27225869 DOI: 10.1038/Srep26800 |
0.29 |
|
| 2019 |
Acharya C, Salzman N, Genta, Sikaroodi M, Hayward M, Fagan A, Gavis EA, White M, Takei H, Nittono H, Pandak WM, Hylemon PB, Gillevet PM, Bajaj JS. P: 11 Cognitive Improvement After Capsular Fecal Microbial Transplant in Hepatic Encephalopathy Is Associated With Changes in Microbial Function and Inflammation The American Journal of Gastroenterology. 114. DOI: 10.14309/01.Ajg.0000582020.43787.96 |
0.29 |
|
| 1987 |
Krafft AE, Winter J, Bokkenheuser VD, Hylemon PB. Cofactor requirements of steroid- 17-20-desmolase and 20α-hydroxysteroid dehydrogenase activities in cell extracts of Clostridium scindens Journal of Steroid Biochemistry. 28: 49-54. PMID 3475510 DOI: 10.1016/0022-4731(87)90123-3 |
0.289 |
|
| 1982 |
Hylemon PB, Fricke RJ, Mosbach EH. Antibacterial properties of bile acid oxazoline compounds Steroids. 40: 347-357. PMID 7184207 DOI: 10.1016/0039-128X(82)90046-0 |
0.289 |
|
| 2009 |
Flint OP, Noor MA, Hruz PW, Hylemon PB, Yarasheski K, Kotler DP, Parker RA, Bellamine A. The role of protease inhibitors in the pathogenesis of HIV-associated lipodystrophy: cellular mechanisms and clinical implications. Toxicologic Pathology. 37: 65-77. PMID 19171928 DOI: 10.1177/0192623308327119 |
0.288 |
|
| 1991 |
Duckworth PF, Vlahcevic ZR, Studer EJ, Gurley EC, Heuman DM, Beg ZH, Hylemon PB. Effect of hydrophobic bile acids on 3-hydroxy-3-methylglutaryl- coenzyme A reductase activity and mRNA levels in the rat Journal of Biological Chemistry. 266: 9413-9418. PMID 2033042 |
0.287 |
|
| 2008 |
Wu X, Gurley EC, Studer E, Chen L, Wang X, Chen J, Wang J, Hylemon P, Pandak WM, Sanyal AJ, Zhang L, Zhou H. W1269 HIV Protease Inhibitors Induce ER Stress and Disrupt Barrier Function in Intestinal Epithelial Cells Gastroenterology. 134: A-669. DOI: 10.1016/S0016-5085(08)63120-0 |
0.285 |
|
| 1987 |
Coleman JP, White WB, Egestad B, Sjövall J, Hylemon PB. Biosynthesis of a novel bile acid nucleotide and mechanism of 7α-dehydroxylation by an intestinal Eubacterium species Journal of Biological Chemistry. 262: 4701-4707. PMID 3558364 |
0.285 |
|
| 2018 |
Bajaj JS, Idilman R, Mabudian L, Hood M, Fagan A, Turan D, White MB, Karakaya F, Wang J, Atalay R, Hylemon PB, Gavis EA, Brown R, Thacker LR, Acharya C, et al. Diet Affects Gut Microbiota and Modulates Hospitalization Risk Differentially In an International Cirrhosis Cohort. Hepatology (Baltimore, Md.). PMID 29350768 DOI: 10.1016/S0168-8278(18)30241-1 |
0.284 |
|
| 2010 |
Cao R, Hu Y, Wang Y, Gurley EC, Studer EJ, Wang X, Hylemon PB, Pandak WM, Sanyal AJ, Zhang L, Zhou H. Prevention of HIV protease inhibitor-induced dysregulation of hepatic lipid metabolism by raltegravir via endoplasmic reticulum stress signaling pathways. The Journal of Pharmacology and Experimental Therapeutics. 334: 530-9. PMID 20472667 DOI: 10.1124/Jpet.110.168484 |
0.283 |
|
| 2012 |
Bajaj JS, Gillevet PM, Hylemon PB. Methanogenesis in irritable bowel syndrome: a lot of hot air? Digestive Diseases and Sciences. 57: 3045-6. PMID 23086113 DOI: 10.1007/S10620-012-2419-6 |
0.281 |
|
| 2001 |
Gupta S, Stravitz RT, Dent P, Hylemon PB. Down-regulation of Cholesterol 7α-Hydroxylase (CYP7A1) Gene Expression by Bile Acids in Primary Rat Hepatocytes is Mediated by the c-Jun N-terminal Kinase Pathway Journal of Biological Chemistry. 276: 15816-15822. PMID 11278771 DOI: 10.1074/jbc.M010878200 |
0.28 |
|
| 2013 |
Zha BS, Wan X, Zhang X, Zha W, Zhou J, Wabitsch M, Wang G, Lyall V, Hylemon PB, Zhou H. HIV protease inhibitors disrupt lipid metabolism by activating endoplasmic reticulum stress and inhibiting autophagy activity in adipocytes. Plos One. 8: e59514. PMID 23533630 DOI: 10.1371/Journal.Pone.0059514 |
0.277 |
|
| 2009 |
Wu X, Cao R, Sun L, Zha W, Pecora BS, Gurley EC, Studer E, Hylemon P, Pandak WM, Sanyal AJ, Zhang L, Zhou H. S1589 Alcohol Promotes HIV Protease Inhibitor-Induced Hepatoxicity By Activating the ER Stress Response in Hepatocytes Gastroenterology. 136: A-820. DOI: 10.1016/S0016-5085(09)63779-3 |
0.277 |
|
| 2007 |
Fang Y, Studer E, Mitchell C, Grant S, Pandak WM, Hylemon PB, Dent P. Conjugated bile acids regulate hepatocyte glycogen synthase activity in vitro and in vivo via Galphai signaling. Molecular Pharmacology. 71: 1122-8. PMID 17200418 DOI: 10.1124/Mol.106.032060 |
0.277 |
|
| 1991 |
Roberts I, Hylemon PB, Michael Holmes W. Rapid method for altering bacterial ribosome-binding sequences for overexpression of proteins in Escherichia coli Protein Expression and Purification. 2: 117-121. PMID 1821779 DOI: 10.1016/1046-5928(91)90059-R |
0.276 |
|
| 2000 |
Seema G, Stravitz RT, Pandak WM, Muller M, Vlahcevic ZR, Hylemon PB. Regulation of MDR2 p-glycoprotein expression by bile salts and cholesterol in rats and primary cultures of rat hepatocytes Gastroenterology. 118: A592. DOI: 10.1016/S0016-5085(00)84507-2 |
0.275 |
|
| 2016 |
Chen T, Huang Z, Jiao C, Yang J, Hylemon P, Zhou H. 670 S1P Promotes Intestinal Epithelial Cell Proliferation via Activation of Sphingosine 1-Phosphate Receptor 2 Gastroenterology. 150: S137. DOI: 10.1016/S0016-5085(16)30561-3 |
0.275 |
|
| 2013 |
Wang Y, Liu R, Zhang L, Gurley EC, Hylemon P, Pandak WM, Sanyal AJ, Zhou H. Tu2032 VSL#3 Probiotic Treatment Prevents Ritonavir-Induced Gastrointestinal Barrier Dysfunction and Dyslipidemia in Mice Gastroenterology. 144: S-909. DOI: 10.1016/S0016-5085(13)63388-0 |
0.275 |
|
| 1993 |
Stravitz RT, Hylemon PB, Heuman DM, Hagey LR, Schteingart CD, Ton-Nu HT, Hofmann AF, Vlahcevic ZR. Transcriptional regulation of cholesterol 7α-hydroxylase mRNA by conjugated bile acids in primary cultures of rat hepatocytes Journal of Biological Chemistry. 268: 13987-13993. PMID 8314765 |
0.275 |
|
| 2017 |
Kang DJ, Hylemon PB, Gillevet PM, Sartor RB, Betrapally NS, Kakiyama G, Sikaroodi M, Takei H, Nittono H, Zhou H, Pandak WM, Yang J, Jiao C, Li X, Lippman HR, et al. Gut microbial composition can differentially regulate bile acid synthesis in humanized mice. Hepatology Communications. 1: 61-70. PMID 29404434 DOI: 10.1002/hep4.1020 |
0.274 |
|
| 2019 |
Bajaj JS, Fagan A, Sikaroodi M, Kakiyama G, Takei H, Degefu Y, Pandak WM, Hylemon PB, Fuchs M, John B, Heuman DM, Gavis E, Nittono H, Patil R, Gillevet PM. Alterations in Skin Microbiomes of Patients With Cirrhosis. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. PMID 30905718 DOI: 10.1016/J.Cgh.2019.03.028 |
0.274 |
|
| 2016 |
Bajaj JS, Ahluwalia V, Steinberg JL, Hobgood S, Boling PA, Godschalk M, Habib S, White MB, Fagan A, Gavis EA, Ganapathy D, Hylemon PB, Stewart KE, Keradman R, Liu EJ, et al. Elderly patients have an altered gut-brain axis regardless of the presence of cirrhosis. Scientific Reports. 6: 38481. PMID 27922089 DOI: 10.1038/Srep38481 |
0.272 |
|
| 1993 |
Vlahcevic ZR, Pandak WM, Hylemon PB, Heuman DM. Role of newly synthesized cholesterol or its metabolites on the regulation of bile acid biosynthesis after short-term biliary diversion in the rat Hepatology. 18: 660-668. PMID 8359807 DOI: 10.1016/0270-9139(93)90368-W |
0.271 |
|
| 2010 |
Wu X, Sun L, Zha W, Studer E, Gurley E, Chen L, Wang X, Hylemon PB, Pandak WM, Sanyal AJ, Zhang L, Wang G, Chen J, Wang JY, Zhou H. HIV protease inhibitors induce endoplasmic reticulum stress and disrupt barrier integrity in intestinal epithelial cells. Gastroenterology. 138: 197-209. PMID 19732776 DOI: 10.1053/J.Gastro.2009.08.054 |
0.269 |
|
| 2014 |
Bajaj JS, Heuman DM, Hylemon PB, Sanyal AJ, Puri P, Sterling RK, Luketic V, Stravitz RT, Siddiqui MS, Fuchs M, Thacker LR, Wade JB, Daita K, Sistrun S, White MB, et al. Randomised clinical trial: Lactobacillus GG modulates gut microbiome, metabolome and endotoxemia in patients with cirrhosis. Alimentary Pharmacology & Therapeutics. 39: 1113-25. PMID 24628464 DOI: 10.1111/Apt.12695 |
0.269 |
|
| 1979 |
Glass TL, Holmes WM, Hylemon PB, Stellwag EJ. Synthesis of guanosine tetra- and pentaphosphates by the obligately anaerobic bacterium Bacteroides thetaiotaomicron in response to molecular oxygen Journal of Bacteriology. 137: 956-962. PMID 422517 DOI: 10.1128/Jb.137.2.956-962.1979 |
0.268 |
|
| 1984 |
Glass TL, Lamppa RS, Hylemon PB. Characterization of 16α-hydroxyprogesterone dehydroxylase in cell extracts of the intestinal anaerobic bacterium, Eubacterium sp. 144 Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 792: 59-64. DOI: 10.1016/0005-2760(84)90282-0 |
0.267 |
|
| 2020 |
Yan J, Yang W, Wang Y, Wu J, Zhao D, Wang X, Gurley E, Hylemon P, Cai W, Zhou H. 320 LIN28A AND SPHINGOSINE-1 PHOSPHATE RECEPTOR 2 IN CHOLESTATIC LIVER INJURY Gastroenterology. 158: S-1266. DOI: 10.1016/S0016-5085(20)33822-1 |
0.266 |
|
| 2019 |
Bajaj JS, Salzman N, Acharya C, Takei H, Kakiyama G, Fagan A, White MB, Gavis EA, Holtz ML, Hayward M, Nittono H, Hylemon PB, Cox IJ, Williams R, Taylor-Robinson SD, et al. Microbial Functional Change is Linked with Clinical Outcomes after Capsular Fecal Transplant in Cirrhosis. Jci Insight. PMID 31751317 DOI: 10.1172/Jci.Insight.133410 |
0.266 |
|
| 1985 |
Hylemon PB, Gurley EC, Kubaska WM, Whitehead TR, Guzelian PS, Vlahcevic ZR. Suitability of primary monolayer cultures of adult rat hepatocytes for studies of cholesterol and bile acid metabolism Journal of Biological Chemistry. 260: 1015-1019. PMID 3968056 |
0.266 |
|
| 2010 |
Zhou H, Sun L, Xiao J, Zhang L, Li X, Studer E, Pandak WM, Hylemon PB. Endoplasmic reticulum stress and atherosclerosis Current Hypertension Reviews. 6: 66-71. DOI: 10.2174/157340210790231744 |
0.266 |
|
| 2005 |
Dent P, Fang Y, Gupta S, Studer E, Mitchell C, Spiegel S, Hylemon PB. Conjugated bile acids promote ERK1/2 and AKT activation via a pertussis toxin-sensitive mechanism in murine and human hepatocytes. Hepatology (Baltimore, Md.). 42: 1291-9. PMID 16317705 DOI: 10.1002/Hep.20942 |
0.265 |
|
| 2018 |
Bajaj JS, Kakiyama G, Savidge TC, Fagan A, Gavis E, Nittono H, Hylemon P, Boonma P, Haag A, Heuman D, Kassam Z, Sikaroodi M, Gillevet PM. 803 - Antibiotic-Associated Disruption of Microbial Composition and Functionality is Restored after Fecal Microbial Transplant in Cirrhosis Gastroenterology. 154: S-1107. DOI: 10.1016/S0016-5085(18)33680-1 |
0.265 |
|
| 1990 |
Pandak WM, Vlahcevic ZR, Heuman DM, Hylemon PB. Regulation of bile acid synthesis. V. Inhibition of conversion of 7-dehydrocholesterol to cholesterol is associated with down-regulation of cholesterol 7α-hydroxylase activity and inhibition of bile acid synthesis Journal of Lipid Research. 31: 2149-2158. PMID 1708805 |
0.265 |
|
| 2019 |
Wang R, Xiang D, Zhao D, Liu R, Li X, Wang Y, Zhu W, Kwong E, Alruwaili W, Hinton M, Yang H, Wang X, Gurley E, Pandak W, Hylemon P, et al. Mo1480 – Altered Expression of Microrna-1/133A and Microrna-155 is Associated with Hepatic Inflammation and Fibrosis in Multidrug Resistance 2 Gene Deficient Mice Gastroenterology. 156: S-1321. DOI: 10.1016/S0016-5085(19)40321-1 |
0.264 |
|
| 1983 |
White BA, Paone DAM, Cacciapuoti AF, Fricke RJ, Mosbach EH, Hylemon PB. Regulation of bile acid 7-dehydroxylase activity by NAD+ and NADH in cell extracts of Eubacterium species V.P.I. 12708 Journal of Lipid Research. 24: 20-27. PMID 6833878 |
0.263 |
|
| 1994 |
Pandak WM, Vlahcevic ZR, Heuman DM, Redford KS, Chiang JYL, Hylemon PB. Effects of different bile salts on steady-state mRNA levels and transcriptional activity of cholesterol 7α-hydroxylase Hepatology. 19: 941-947. PMID 8138269 DOI: 10.1016/0270-9139(94)90295-X |
0.263 |
|
| 2021 |
Xue R, Su L, Lai S, Wang Y, Zhao D, Fan J, Chen W, Hylemon PB, Zhou H. Bile Acid Receptors and the Gut-Liver Axis in Nonalcoholic Fatty Liver Disease. Cells. 10. PMID 34831031 DOI: 10.3390/cells10112806 |
0.263 |
|
| 1993 |
Jones MP, Pandak WM, Heuman DM, Chiang JYL, Hylemon PB, Vlahcevic ZR. Cholesterol 7α-hydroxylase: Evidence for transcriptional regulation by cholesterol or metabolic products of cholesterol in the rat Journal of Lipid Research. 34: 885-892. PMID 8354954 |
0.262 |
|
| 2014 |
Zhang X, Cao R, Liu R, Zhao R, Huang Y, Gurley EC, Hylemon PB, Pandak WM, Wang G, Zhang L, Li X, Zhou H. Reduction of the HIV protease inhibitor-induced ER stress and inflammatory response by raltegravir in macrophages. Plos One. 9: e90856. PMID 24625618 DOI: 10.1371/Journal.Pone.0090856 |
0.262 |
|
| 1988 |
White WB, Franklund CV, Coleman JP, Hylemon PB. Evidence for a multigene family involved in bile acid 7-dehydroxylation in Eubacterium sp. strain VPI 12708 Journal of Bacteriology. 170: 4555-4561. PMID 3170477 DOI: 10.1128/Jb.170.10.4555-4561.1988 |
0.261 |
|
| 2016 |
Bajaj JS, Sterling RK, Betrapally NS, Nixon DE, Fuchs M, Daita K, Heuman DM, Sikaroodi M, Hylemon PB, White MB, Ganapathy D, Gillevet PM. HCV eradication does not impact gut dysbiosis or systemic inflammation in cirrhotic patients. Alimentary Pharmacology & Therapeutics. PMID 27417456 DOI: 10.1016/S0168-8278(16)01141-7 |
0.261 |
|
| 2017 |
Bajaj JS, Liu EJ, Kheradman R, Fagan A, Heuman DM, White M, Gavis EA, Hylemon P, Sikaroodi M, Gillevet PM. Fungal dysbiosis in cirrhosis. Gut. PMID 28578302 DOI: 10.1136/Gutjnl-2016-313170 |
0.261 |
|
| 1993 |
Stravitz RT, Hylemon PB, Vlahcevic ZR. The catabolism of cholesterol Current Opinion in Lipidology. 4: 223-229. DOI: 10.1097/00041433-199306000-00008 |
0.26 |
|
| 2014 |
Bajaj J, Ahluwalia V, Sikaroodi M, Wade J, White M, Heuman D, Gilles H, Unser A, Hylemon P, Gillevet P. P499 ALTERED GUT MICROBIOME IS ASSOCIATED WITH NEURO-INFLAMMATION ON BRAIN MRI IN CIRRHOSIS: IMPLICATIONS FOR THE GUT–LIVER–BRAIN AXIS Journal of Hepatology. 60: S235-S236. DOI: 10.1016/S0168-8278(14)60661-9 |
0.26 |
|
| 1996 |
Dawson JA, Mallonee DH, Björkhem I, Hylemon PB. Expression and characterization of a C24 bile acid 7α-dehydratase from Eubacterium sp. strain VPI 12708 in Escherichia coli Journal of Lipid Research. 37: 1258-1267. PMID 8808760 |
0.26 |
|
| 1972 |
Hylemon PB, Phibbs PV. Independant regulation of hexose catabolizing enzymes and glucose transport activity in Pseudomonas aeruginosa Biochemical and Biophysical Research Communications. 48: 1041-1048. PMID 4626609 DOI: 10.1016/0006-291X(72)90813-3 |
0.259 |
|
| 2017 |
Yang J, Li YZ, Hylemon PB, Zhang LY, Zhou HP. Cordycepin inhibits LPS-induced inflammatory responses by modulating NOD-Like Receptor Protein 3 inflammasome activation. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 95: 1777-1788. PMID 28962083 DOI: 10.1016/J.Biopha.2017.09.103 |
0.259 |
|
| 2010 |
Zha W, Liang G, Xiao J, Studer EJ, Hylemon PB, Pandak WM, Wang G, Li X, Zhou H. Berberine inhibits HIV protease inhibitor-induced inflammatory response by modulating ER stress signaling pathways in murine macrophages. Plos One. 5: e9069. PMID 20161729 DOI: 10.1371/Journal.Pone.0009069 |
0.255 |
|
| 1979 |
Feighner SD, Bokkenheuser VD, Winter J, Hylemon PB. Characterization of a C21 neutral steroid hormone transforming enzyme, 21-dehydroxylase, in crude cell extracts of Eubacterium lentum Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 574: 154-163. PMID 38850 DOI: 10.1016/0005-2760(79)90094-8 |
0.255 |
|
| 2009 |
Cao R, Hu Y, Wu X, Sun L, Zha W, Pecora BS, Gurley EC, Studer E, Hylemon P, Pandak WM, Sanyal AJ, Zhou H. 534 Effect of HIV Integrase Inhibitor On HIV Protease Inhibitor-Induced ER Stress and Disregulation of Lipid Metabolism in Hepatocytes Gastroenterology. 136: A-802. DOI: 10.1016/S0016-5085(09)63700-8 |
0.255 |
|
| 2018 |
Bajaj JS, Idiliman R, Mabudian L, Hood M, Fagan A, Turan D, White MB, Karakaya F, Wang J, Atalay R, Hylemon P, Gavis E, Brown R, Heuman D, Sikaroodi M, et al. 247 - Diet Affects Gut Microbiota and Modulates Hospitalization Risk Differentially in an International Cirrhosis Cohort Gastroenterology. 154. DOI: 10.1016/S0016-5085(18)33598-4 |
0.255 |
|
| 1990 |
Franklund CV, De Prada P, Hylemon PB. Purification and characterization of a microbial, NADP-dependent bile acid 7α-hydroxysteroid dehydrogenase Journal of Biological Chemistry. 265: 9842-9849. PMID 2351678 |
0.255 |
|
| 1991 |
Hylemon PB, Melone PD, Franklund CV, Lund E, Bjorkhem I. Mechanism of intestinal 7α-dehydroxylation of cholic acid: Evidence that allo-deoxycholic acid is an inducible side-product Journal of Lipid Research. 32: 89-96. PMID 2010697 |
0.255 |
|
| 2019 |
Kakiyama G, Marques D, Takei H, Nittono H, Erickson S, Fuchs M, Rodriguez-Agudo D, Gil G, Hylemon PB, Zhou H, Bajaj JS, Pandak WM. Mitochondrial oxysterol biosynthetic pathway gives evidence for CYP7B1 as controller of regulatory oxysterols. The Journal of Steroid Biochemistry and Molecular Biology. PMID 30710743 DOI: 10.1016/j.jsbmb.2019.01.011 |
0.254 |
|
| 2018 |
Bajaj JS, Thacker LR, Fagan A, White MB, Gavis EA, Hylemon PB, Brown R, Acharya C, Heuman DM, Fuchs M, Dalmet S, Sikaroodi M, Gillevet PM. Gut microbial RNA and DNA analysis predicts hospitalizations in cirrhosis. Jci Insight. 3. PMID 29515036 DOI: 10.1172/Jci.Insight.98019 |
0.254 |
|
| 2005 |
Zhou H, Pandak WM, Lyall V, Natarajan R, Hylemon PB. HIV protease inhibitors activate the unfolded protein response in macrophages: implication for atherosclerosis and cardiovascular disease. Molecular Pharmacology. 68: 690-700. PMID 15976036 DOI: 10.1124/Mol.105.012898 |
0.253 |
|
| 2015 |
Bajaj JS, Betrapally NS, Hylemon PB, Thacker LR, Daita K, Kang DJ, White MB, Unser AB, Fagan A, Gavis EA, Sikaroodi M, Dalmet S, Heuman DM, Gillevet PM. Gut Microbiota Alterations can predict Hospitalizations in Cirrhosis Independent of Diabetes Mellitus. Scientific Reports. 5: 18559. PMID 26692421 DOI: 10.1038/Srep18559 |
0.251 |
|
| 1974 |
Hylemon PB, Phibbs PV. Evidence against the presence of cyclic AMP and related enzymes in selected strains of Bacteroides fragilis Biochemical and Biophysical Research Communications. 60: 88-95. PMID 4370920 DOI: 10.1016/0006-291X(74)90176-4 |
0.251 |
|
| 1999 |
Mallonee DH, Hylemon PB. Use of a short A/T-rich cassette for enhanced expression of cloned genes in Escherichia coli Applied Biochemistry and Biotechnology - Part B Molecular Biotechnology. 11: 27-35. PMID 10367280 DOI: 10.1007/Bf02789174 |
0.251 |
|
| 1989 |
Krafft AE, Hylemon PB. Purification and characterization of a novel form of 20α-hydroxysteroid dehydrogenase from Clostridium scindens Journal of Bacteriology. 171: 2925-2932. PMID 2722736 DOI: 10.1128/Jb.171.6.2925-2932.1989 |
0.25 |
|
| 2018 |
Bajaj JS, Savidge T, Kassam ZA, Hylemon PB, Gillevet PM. Fecal Microbial Transplant for Antibiotic-Associated Disruption in Cirrhosis. Hepatology (Baltimore, Md.). PMID 29774575 DOI: 10.1002/Hep.30092 |
0.25 |
|
| 2013 |
Zha W, Wang G, Xu W, Liu X, Wang Y, Zha BS, Shi J, Zhao Q, Gerk PM, Studer E, Hylemon PB, Pandak WM, Zhou H. Inhibition of P-glycoprotein by HIV protease inhibitors increases intracellular accumulation of berberine in murine and human macrophages. Plos One. 8: e54349. PMID 23372711 DOI: 10.1371/Journal.Pone.0054349 |
0.248 |
|
| 2014 |
Bajaj J, Heuman D, Hylemon P, Sanyal A, Sterling R, Stravitz R, Puri P, Sikaroodi M, Thacker L, Wade J, Gillevet P. P456 SYSTEMS BIOLOGY ANALYSIS OF PROBIOTIC LACTOBACILLUS GG IN CIRRHOTIC PATIENTS WITH MINIMAL HEPATIC ENCEPHALOPATHY: A RANDOMIZED DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL Journal of Hepatology. 60: S221. DOI: 10.1016/S0168-8278(14)60618-8 |
0.247 |
|
| 2013 |
Dougherty U, Mustafi R, Wang Y, Musch MW, Nadimpalli A, Hart J, Konda VJ, Pekow J, Hagey L, Hylemon P, Joseph LJ, Chang EB, Li YC, Bissonnette M. 79 Vitamin D Receptor Inactivation Alters the Colonic Microbiome and Increases Secondary Bile Acids and Colonic Tumorigenesis Gastroenterology. 144: S-17. DOI: 10.1016/S0016-5085(13)60059-1 |
0.245 |
|
| 1997 |
Rao YP, Stravitz RT, Vlahcevic ZR, Gurley EC, Sando JJ, Hylemon PB. Activation of protein kinase C α and δ by bile acids: Correlation with bile acid structure and diacylglycerol formation Journal of Lipid Research. 38: 2446-2454. PMID 9458268 |
0.244 |
|
| 1988 |
Roberts I, Holmes WM, Hylemon PB. Development of a new shuttle plasmid system for Escherichia coli and Clostridium perfringens Applied and Environmental Microbiology. 54: 268-270. PMID 2894200 DOI: 10.1128/Aem.54.1.268-270.1988 |
0.244 |
|
| 1979 |
Stellwag EJ, Hylemon PB. 7α Dehydroxylation of cholic acid and chenodeoxycholic acid by Clostridium leptum Journal of Lipid Research. 20: 325-333. PMID 36438 |
0.242 |
|
| 1992 |
Pandak WM, Vlahcevic ZR, Chiang JYL, Heuman DM, Hylemon PB. Bile acid synthesis. VI. Regulation of cholesterol 7α-hydroxylase by taurocholate and mevalonate Journal of Lipid Research. 33: 659-668. PMID 1619360 |
0.241 |
|
| 1988 |
White WB, Coleman JP, Hylemon PB. Molecular cloning of a gene encoding a 45,000-dalton polypeptide associated with bile acid 7-dehydroxylation in Eubacterium sp. strain VPI 12708 Journal of Bacteriology. 170: 611-616. PMID 2448288 DOI: 10.1128/Jb.170.2.611-616.1988 |
0.24 |
|
| 2019 |
Li X, Liu R, Zhu W, Zhao D, Wang X, Hylemon P, Zhou H. 249 – Cholangiocyte-Derived Exosomal Lncrna H19 Plays a Critical Role in Regulating Macrophage Activation Under Cholestatic Conditions Gastroenterology. 156: S-1187. DOI: 10.1016/S0016-5085(19)39942-1 |
0.239 |
|
| 1985 |
Stokes NA, Hylemon PB. Characterization of †4-3-ketosteroid-5β-reductase and 3β-hydroxysteroid dehydrogenase in cell extracts of Clostridium innocuum Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 836: 255-261. PMID 3861198 DOI: 10.1016/0005-2760(85)90073-6 |
0.236 |
|
| 2016 |
Bajaj JS, Hylemon P, White MB, Unser A, Sikaroodi M, Heuman D, Sterling R, Fagan A, Gillevet PM. 1096 Chronic Opioid Therapy Is Associated With Gut Dysbiosis in Cirrhosis Independent of Cirrhosis Severity Gastroenterology. 150: S219. DOI: 10.1016/S0168-8278(16)00740-6 |
0.235 |
|
| 2015 |
Liu R, Li X, Jiang Z, Hylemon P, Zhou H, Zhang L. Sa1692 Taurocholate Induces Cyclooxygenase-2 Through Sphingosine 1-Phosphate Receptor 2 and Promotes Cholangiocarcinoma Cell Growth Gastroenterology. 148: S-1013. DOI: 10.1016/S0016-5085(15)33460-0 |
0.233 |
|
| 2016 |
Bajaj JS, Sterling R, Hylemon P, White MB, Unser A, Heuman D, Fuchs M, Nixon D, Sikaroodi M, Gillevet PM. 1095 HCV Eradication Does Not Impact Gut Dysbiosis or Systemic Inflammation in Cirrhotic Patients Gastroenterology. 150. DOI: 10.1016/S0016-5085(16)30810-1 |
0.232 |
|
| 2011 |
Zhou X, Shi R, Wang X, Campbell DJ, Studer E, Hylemon P, Sirica AE, Zhou H. Differential Gene Expression of Sphingosine Kinases and Sphingosine-1 Phosphate Receptors in Cultured Neu-Transformed Versus Spontaneously-Transformed Rat Cholangiocytes and Corresponding Cholangiocarcinomas Gastroenterology. 140: S-938. DOI: 10.1016/S0016-5085(11)63889-4 |
0.231 |
|
| 2020 |
Kakiyama G, Marques D, Martin R, Takei H, Rodriguez-Agudo D, LaSalle SA, Hashiguchi T, Liu X, Green RM, Erickson SK, Gil G, Fuchs M, Suzuki M, Murai T, Nittono H, ... Hylemon PB, et al. Insulin resistance dysregulates CYP7B1 leading to oxysterol accumulation: a pathway for NAFL to NASH transition. Journal of Lipid Research. PMID 33008924 DOI: 10.1194/jlr.RA120000924 |
0.231 |
|
| 1994 |
Stravitz RT, Vlahcevic ZR, Pandak WM, Stolz A, Hylemon PB. Regulation of rat hepatic 3α-hydroxysteroid dehydrogenase in vivo and in primary cultures of rat hepatocytes Journal of Lipid Research. 35: 239-247. PMID 8169527 |
0.23 |
|
| 1984 |
Paone DA, Hylemon PB. HPLC purification and preparation of antibodies to cholic acid-inducible polypeptides from Eubacterium sp. V.P.I. 12708 Journal of Lipid Research. 25: 1343-1349. PMID 6442337 |
0.23 |
|
| 2006 |
Zhou H, Pandak WM, Hylemon PB. Cellular mechanisms of lipodystrophy induction by HIV protease inhibitors Future Lipidology. 1: 163-172. DOI: 10.2217/17460875.1.2.163 |
0.229 |
|
| 1988 |
Coleman JP, White WB, Lijewski M, Hylemon PB. Nucleotide sequence and regulation of a gene involved in bile acid 7-dehydroxylation by Eubacterium sp. strain VPI 12708 Journal of Bacteriology. 170: 2070-2077. PMID 2834320 DOI: 10.1128/Jb.170.5.2070-2077.1988 |
0.229 |
|
| 1991 |
Pandak WM, Li YC, Chiang JYL, Studer EJ, Gurley EC, Heuman DM, Vlahcevic ZR, Hylemon PB. Regulation of cholesterol 7α-hydroxylase mRNA and transcriptional activity by taurocholate and cholesterol in the chronic biliary diverted rat Journal of Biological Chemistry. 266: 3416-3421. PMID 1995604 |
0.228 |
|
| 2015 |
Wang Y, Liu R, Hylemon P, Zhou H. Sa1695 Conjugated Bile Acids Promote Cholangiocyte Proliferation via Activation of Sphingosine-1-Phosphate Receptor 2 Gastroenterology. 148: S-1013. DOI: 10.1016/S0016-5085(15)33463-6 |
0.222 |
|
| 2021 |
Wang Y, Lin W, Brown JE, Chen L, Pandak WM, Hylemon PB, Ren S. 25-hydroxycholesterol 3-sulfate is an endogenous ligand of DNA methyltransferases in hepatocytes. Journal of Lipid Research. 100063. PMID 33705741 DOI: 10.1016/j.jlr.2021.100063 |
0.22 |
|
| 1991 |
Heuman DM, Pandak WM, Hylemon PB, Vlahcevic ZR. Conjugates of ursodeoxycholate protect against cytotoxicity of more hydrophobic bile salts: In vitro studies in rat hepatocytes and human erythrocytes Hepatology. 14: 920-926. PMID 1937396 |
0.219 |
|
| 1986 |
Roberts I, Holmes WM, Hylemon PB. Modified plasmid isolation method for Clostridium perfringens and Clostridium absonum Applied and Environmental Microbiology. 52: 197-199. PMID 2873789 DOI: 10.1128/Aem.52.1.197-199.1986 |
0.219 |
|
| 2022 |
Sarkar J, Aoki H, Wu R, Aoki M, Hylemon P, Zhou H, Takabe K. Conjugated Bile Acids Accelerate Progression of Pancreatic Cancer Metastasis via S1PR2 Signaling in Cholestasis. Annals of Surgical Oncology. PMID 36396870 DOI: 10.1245/s10434-022-12806-4 |
0.218 |
|
| 1994 |
Hylemon PB, Stravitz RT, Vlahcevic ZR. Molecular genetics and regulation of bile acid biosynthesis Progress in Liver Diseases. 12: 99-120. PMID 7746879 |
0.21 |
|
| 2002 |
Qiao L, Yacoub A, Studer E, Gupta S, Pei XY, Grant S, Hylemon PB, Dent P. Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes. Hepatology (Baltimore, Md.). 35: 779-89. PMID 11915023 DOI: 10.1053/Jhep.2002.32533 |
0.209 |
|
| 2010 |
Ren S, Zhang S, Xu L, Hylemon P, Heuman DM, Pandak WM. 541 Is 25-Hydroxycholesterol 3-Sulfate an Endogenous Ligand of Ppargamma? Gastroenterology. 138: S-791. DOI: 10.1016/S0016-5085(10)63644-X |
0.208 |
|
| 1990 |
Mallonee DH, White WB, Hylemon PB. Cloning and sequencing of a bile acid-inducible operon from Eubacterium sp. strain VPI 12708 Journal of Bacteriology. 172: 7011-7019. PMID 2254270 DOI: 10.1128/Jb.172.12.7011-7019.1990 |
0.207 |
|
| 2004 |
Ren S, Hylemon PB, Marques D, Gurley E, Bodhan P, Hall E, Redford K, Gil G, Pandak M.D. WM. Overexpression of cholesterol transporter StAR increasesIn Vivo rates of bile acid synthesis in the rat and mouse Hepatology. 40: 910-917. DOI: 10.1002/hep.1840400421 |
0.206 |
|
| 1990 |
Vlahcevic ZR, Gurley EC, Heuman DM, Hylemon PB. Bile salts in submicellar concentrations promote bidirectional cholesterol transfer (exchange) as a function of their hydrophobicity Journal of Lipid Research. 31: 1063-1071. PMID 2373956 |
0.205 |
|
| 2023 |
Wang Y, Pandak WM, Hylemon PB, Min HK, Min J, Fuchs M, Sanyal AJ, Ren S. Cholestenoic Acid as Endogenous Epigenetic Regulator Decreases Hepatocyte Lipid Accumulation in Vitro and in Vivo. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 37961761 DOI: 10.1152/ajpgi.00184.2023 |
0.203 |
|
| 2012 |
Bajaj JS, Hylemon PB, Younossi Z. The Intestinal Microbiota and Liver Disease The American Journal of Gastroenterology Supplements. 1: 9-14. DOI: 10.1038/AJGSUP.2012.3 |
0.202 |
|
| 2022 |
Wang Y, Tai YL, Way G, Zeng J, Zhao D, Su L, Jiang X, Jackson KG, Wang X, Gurley EC, Liu J, Liu J, Chen W, Wang XY, Sanyal AJ, ... Hylemon PB, et al. RNA binding protein HuR protects against NAFLD by suppressing long noncoding RNA H19 expression. Cell & Bioscience. 12: 172. PMID 36224648 DOI: 10.1186/s13578-022-00910-7 |
0.2 |
|
| 1984 |
Winter J, Morris GN, O'Rourke-Locascio S, Bokkenheuser VD, Mosbach EH, Cohen BI, Hylemon PB. Mode of action of steroid desmolase and reductases synthesized by Clostridium "scindens" (formerly Clostridium strain 19) Journal of Lipid Research. 25: 1124-1131. PMID 6512418 |
0.196 |
|
| 2004 |
Fang Y, Han SI, Mitchell C, Gupta S, Studer E, Grant S, Hylemon PB, Dent P. Bile acids induce mitochondrial ROS, which promote activation of receptor tyrosine kinases and signaling pathways in rat hepatocytes. Hepatology (Baltimore, Md.). 40: 961-71. PMID 15382121 DOI: 10.1002/hep.20385 |
0.194 |
|
| 1994 |
De Prada P, Setchell KDR, Hylemon PB. Purification and characterization of a novel 17α-hydroxysteroid dehydrogenase from an intestinal Eubacterium sp. VPI 12708 Journal of Lipid Research. 35: 922-929. PMID 8071614 |
0.194 |
|
| 1996 |
Berr F, Kullak-Ublick GA, Paumgartner G, Monzing W, Hylemon PB. 7α-Dehydroxylating bacteria enhance deoxycholic acid input and cholesterol saturation of bile in patients with gallstones Gastroenterology. 111: 1611-1620. PMID 8942741 |
0.194 |
|
| 2024 |
Wang Y, Zhao D, Su L, Tai YL, Way GW, Zeng J, Yan Q, Xu Y, Wang X, Gurley EC, Zhou XQ, Liu J, Liu J, Chen W, Hylemon PB, et al. Therapeutic potential of berberine in attenuating cholestatic liver injury: insights from a PSC mouse model. Cell & Bioscience. 14: 14. PMID 38273376 DOI: 10.1186/s13578-024-01195-8 |
0.193 |
|
| 1982 |
White BA, Fricke RJ, Hylemon PB. 7β-Dehydroxylation of ursodeoxycholic acid by whole cells and cell extracts of the intestinal anaerobic bacterium, Eubacterium species V.P.I. 12708 Journal of Lipid Research. 23: 145-153. PMID 7057103 |
0.191 |
|
| 1995 |
Doerner KC, Gurley EC, Vlahcevic ZR, Hylemon PB. Regulation of cholesterol 7α-hydroxylase expression by sterols in primary rat hepatocyte cultures Journal of Lipid Research. 36: 1168-1177. PMID 7665995 |
0.187 |
|
| 2020 |
Bajaj JS, Sikaroodi M, Shamsaddini A, Henseler Z, Santiago-Rodiguez T, Acharya C, Fagan A, Hylemon PB, Fuchs M, Gavis E, Ward T, Knights D, Gillevet PM. Interaction of bacterial metagenome and virome in patients with cirrhosis and hepatic encephalopathy. Gut. PMID 32998876 DOI: 10.1136/gutjnl-2020-322470 |
0.182 |
|
| 1995 |
Stravitz RT, Vlahcevic ZR, Gurley EC, Hylemon PB. Repression of cholesterol 7α-hydroxylase transcription by bile acids is mediated through protein kinase C in primary cultures of rat hepatocytes Journal of Lipid Research. 36: 1359-1369. PMID 7666012 |
0.179 |
|
| 1991 |
Heuman DM, Mills AS, McCall J, Hylemon PB, Pandak WM, Vlahcevic ZR. Conjugates of ursodeoxycholate protect against cholestasis and hepatocellular necrosis caused by more hydrophobic bile salts: In vivo studies in the rat Gastroenterology. 100: 203-211. PMID 1983822 |
0.176 |
|
| 1992 |
Hylemon PB, Gurley EC, Stravitz RT, Litz JS, Pandak WM, Chiang JYL, Vlahcevic ZR. Hormonal regulation of cholesterol 7α-hydroxylase mRNA levels and transcriptional activity in primary rat hepatocyte cultures Journal of Biological Chemistry. 267: 16866-16871. PMID 1512229 |
0.174 |
|
| 2021 |
Zhang Y, Kang JD, Zhao D, Ghosh SS, Wang Y, Tai Y, Gonzalez-Maeso J, Sikaroodi M, Gillevet PM, Lippman HR, Hylemon PB, Zhou H, Bajaj JS. Hepatic Branch Vagotomy Modulates the Gut-Liver-Brain Axis in Murine Cirrhosis. Frontiers in Physiology. 12: 702646. PMID 34248683 DOI: 10.3389/fphys.2021.702646 |
0.172 |
|
| 2019 |
Bajaj JS, Fagan A, White MB, Wade JB, Hylemon PB, Heuman DM, Fuchs M, John BV, Acharya C, Sikaroodi M, Gillevet PM. Specific Gut and Salivary Microbiota Patterns Are Linked With Different Cognitive Testing Strategies in Minimal Hepatic Encephalopathy. The American Journal of Gastroenterology. PMID 30816877 DOI: 10.14309/Ajg.0000000000000102 |
0.168 |
|
| 2021 |
Wang Y, Pandak WM, Lesnefsky EJ, Hylemon PB, Ren S. 25-Hydroxycholesterol 3-Sulfate Recovers Acetaminophen Induced Acute Liver Injury via Stabilizing Mitochondria in Mouse Models. Cells. 10. PMID 34831255 DOI: 10.3390/cells10113027 |
0.168 |
|
| 1991 |
Lalwani ND, Hylemon PB, Strom SC. Altered levels of phosphoinositide metabolites and activation of guanine-nucleotide dependent phospholipase C in rat hepatic tumors Journal of Cellular Physiology. 147: 354-361. PMID 1645743 |
0.166 |
|
| 1997 |
Pandak WM, Heuman DM, Redford K, Stravitz RT, Chiang JYL, Hylemon PB, Vlahcevic ZR. Hormonal regulation of cholesterol 7α-hydroxylase specific activity, mRNA levels, and transcriptional activity in vivo in the rat Journal of Lipid Research. 38: 2483-2491. PMID 9458272 |
0.162 |
|
| 1995 |
Ghosh S, Mallonee DH, Hylemon PB, Grogan WM. Molecular cloning and expression of rat hepatic neutral cholesteryl ester hydrolase. Biochimica Et Biophysica Acta. 1259: 305-12. PMID 8541339 DOI: 10.1016/0005-2760(95)00184-0 |
0.16 |
|
| 1983 |
Macdonald IA, White BA, Hylemon PB. Separation of 7 alpha- and 7 beta-hydroxysteroid dehydrogenase activities from clostridium absonum ATCC# 27555 and cellular response of this organism to bile acid inducers Journal of Lipid Research. 24: 1119-1126. PMID 6579144 |
0.159 |
|
| 1980 |
Feighner SD, Hylemon PB. Characterization of a corticosteroid 21-dehydroxylase from the intestinal anaerobic bacterium, Eubacterium lentum Journal of Lipid Research. 21: 585-593. PMID 6967506 |
0.159 |
|
| 1982 |
Winter J, O'Rourke S, Bokkenheuser VD, Hylemon PB, Glass TL. 16α-Dehydration of corticoids by bacteria isolated from rat fecal flora Journal of Steroid Biochemistry. 16: 231-237. PMID 7078162 DOI: 10.1016/0022-4731(82)90171-6 |
0.158 |
|
| 2007 |
Mitchell C, Park MA, Zhang G, Han SI, Harada H, Franklin RA, Yacoub A, Li PL, Hylemon PB, Grant S, Dent P. 17-Allylamino-17-demethoxygeldanamycin enhances the lethality of deoxycholic acid in primary rodent hepatocytes and established cell lines. Molecular Cancer Therapeutics. 6: 618-32. PMID 17308059 DOI: 10.1158/1535-7163.Mct-06-0532 |
0.157 |
|
| 2021 |
Wang Y, Hylemon PB, Zhou H. Long non-coding RNA H19: A key player in liver diseases. Hepatology (Baltimore, Md.). PMID 33630308 DOI: 10.1002/hep.31765 |
0.154 |
|
| 2022 |
Sarkar J, Aoki H, Wu R, Aoki M, Hylemon P, Zhou H, Takabe K. ASO Visual Abstract: Conjugated Bile Acids Accelerate Progression of Pancreatic Cancer Metastasis via S1PR2 Signaling in Cholestasis. Annals of Surgical Oncology. PMID 36480110 DOI: 10.1245/s10434-022-12915-0 |
0.153 |
|
| 2022 |
Wolstenholme JT, Saunders JM, Smith M, Kang JD, Hylemon PB, González-Maeso J, Fagan A, Zhao D, Sikaroodi M, Herzog J, Shamsaddini A, Peña-Rodríguez M, Su L, Tai YL, Zheng J, et al. Reduced alcohol preference and intake after fecal transplant in patients with alcohol use disorder is transmissible to germ-free mice. Nature Communications. 13: 6198. PMID 36261423 DOI: 10.1038/s41467-022-34054-6 |
0.152 |
|
| 2019 |
Liu R, Ahluwalia V, Kang JD, Ghosh SS, Zhou H, Li Y, Zhao D, Gurley E, Li X, White MB, Fagan A, Lippman HR, Wade JB, Hylemon PB, Bajaj JS. Effect of Increasing Age on Brain Dysfunction in Cirrhosis. Hepatology Communications. 3: 63-73. PMID 30619995 DOI: 10.1002/hep4.1286 |
0.151 |
|
| 2023 |
Wang Y, Zeng J, Chen W, Fan J, Hylemon PB, Zhou H. Long Noncoding RNA H19: A Novel Oncogene in Liver Cancer. Non-Coding Rna. 9. PMID 36960964 DOI: 10.3390/ncrna9020019 |
0.148 |
|
| 2002 |
Qiao L, McKinstry R, Gupta S, Gilfor D, Windle JJ, Hylemon PB, Grant S, Fisher PB, Dent P. Cyclin kinase inhibitor p21 potentiates bile acid-induced apoptosis in hepatocytes that is dependent on p53. Hepatology (Baltimore, Md.). 36: 39-48. PMID 12085347 DOI: 10.1053/Jhep.2002.33899 |
0.146 |
|
| 2003 |
Qiao L, Han SI, Fang Y, Park JS, Gupta S, Gilfor D, Amorino G, Valerie K, Sealy L, Engelhardt JF, Grant S, Hylemon PB, Dent P. Bile acid regulation of C/EBPbeta, CREB, and c-Jun function, via the extracellular signal-regulated kinase and c-Jun NH2-terminal kinase pathways, modulates the apoptotic response of hepatocytes. Molecular and Cellular Biology. 23: 3052-66. PMID 12697808 DOI: 10.1128/Mcb.23.9.3052-3066.2003 |
0.145 |
|
| 1993 |
Purdum PP, Ulissi A, Hylemon PB, Shiffman ML, Moore EW. Cultured human gallbladder epithelia: Methods and partial characterization of a carcinoma-derived model Laboratory Investigation. 68: 345-353. PMID 7680730 |
0.143 |
|
| 2005 |
Dent P, Han SI, Mitchell C, Studer E, Yacoub A, Grandis J, Grant S, Krystal GW, Hylemon PB. Inhibition of insulin/IGF-1 receptor signaling enhances bile acid toxicity in primary hepatocytes. Biochemical Pharmacology. 70: 1685-96. PMID 16207485 DOI: 10.1016/J.Bcp.2005.08.020 |
0.143 |
|
| 2008 |
Zhang G, Park MA, Mitchell C, Walker T, Hamed H, Studer E, Graf M, Rahmani M, Gupta S, Hylemon PB, Fisher PB, Grant S, Dent P. Multiple cyclin kinase inhibitors promote bile acid-induced apoptosis and autophagy in primary hepatocytes via p53-CD95-dependent signaling. The Journal of Biological Chemistry. 283: 24343-58. PMID 18614532 DOI: 10.1074/Jbc.M803444200 |
0.141 |
|
| 2004 |
Han SI, Studer E, Gupta S, Fang Y, Qiao L, Li W, Grant S, Hylemon PB, Dent P. Bile Acids Enhance the Activity of the Insulin Receptor and Glycogen Synthase in Primary Rodent Hepatocytes Hepatology. 39: 456-463. PMID 14767998 DOI: 10.1002/Hep.20043 |
0.141 |
|
| 2022 |
Awoniyi M, Wang J, Ngo B, Meadows V, Tam J, Viswanathan A, Lai Y, Montgomery S, Farmer M, Kummen M, Thingholm L, Schramm C, Bang C, Franke A, Lu K, ... ... Hylemon PB, et al. Protective and aggressive bacterial subsets and metabolites modify hepatobiliary inflammation and fibrosis in a murine model of PSC. Gut. PMID 35705368 DOI: 10.1136/gutjnl-2021-326500 |
0.14 |
|
| 2011 |
Boini KM, Xia M, Li C, Zhang C, Payne LP, Abais JM, Poklis JL, Hylemon PB, Li PL. Acid sphingomyelinase gene deficiency ameliorates the hyperhomocysteinemia-induced glomerular injury in mice. The American Journal of Pathology. 179: 2210-9. PMID 21893018 DOI: 10.1016/J.Ajpath.2011.07.019 |
0.139 |
|
| 1998 |
Ghosh S, Natarajan R, Pandak WM, Hylemon PB, Grogan WM. Regulation of hepatic neutral cholesteryl ester hydrolase by hormones and changes in cholesterol flux. American Journal of Physiology. Gastrointestinal and Liver Physiology. 274: G662-G668. PMID 29585283 DOI: 10.1152/ajpgi.1998.274.4.G662 |
0.137 |
|
| 2000 |
Park JS, Qiao L, Gilfor D, Yan Yang M, Hylemon PB, Benz C, Darlington G, Firestone G, Fisher PB, Dent P. A role for both ets and C/EBP transcription factors and mRNA stabilization in the MAPK-dependent increase in p21 Cip-1/WAF1/mda6 protein levels in primary hepatocytes Molecular Biology of the Cell. 11: 2915-2932. PMID 10982390 DOI: 10.1091/Mbc.11.9.2915 |
0.134 |
|
| 1980 |
Glass TL, Hylemon PB. Characterization of a pyridine nucleotide-nonspecific glutamate dehydrogenase from Bacteroides thetaiotaomicron Journal of Bacteriology. 141: 1320-1330. PMID 7364728 |
0.129 |
|
| 2008 |
Park MA, Zhang G, Norris J, Hylemon PB, Fisher PB, Grant S, Dent P. Regulation of autophagy by ceramide-CD95-PERK signaling Autophagy. 4: 929-931. PMID 18719356 DOI: 10.4161/Auto.6732 |
0.127 |
|
| 1981 |
Bokkenheuser VD, Winter J, Hylemon PB, Ayengar NK, Mosbach EH. Dehydroxylation of 16α-hydroxyprogesterone by fecal flora of man and rat Journal of Lipid Research. 22: 95-102. PMID 7217789 |
0.124 |
|
| 2024 |
Bajaj JS, Fagan A, Gavis EA, Mousel T, Gallagher ML, Puri P, Fuchs M, Davis BC, Hylemon PB, Zhou H, Ahluwalia V, Cadrain R, Sikaroodi M, Gillevet PM. The RIVET RCT: Rifamycin SV MMX improves muscle mass, physical function, and ammonia in cirrhosis and minimal encephalopathy. Hepatology Communications. 8. PMID 38315140 DOI: 10.1097/HC9.0000000000000384 |
0.12 |
|
| 1977 |
Siegel LS, Hylemon PB, Phibbs PV. Cyclic adenosine 3',5' monophosphate levels and activities of adenylate cyclase and cyclic adenosine 3',5' monophosphate phosphodiesterase in Pseudomonas and Bacteroides Journal of Bacteriology. 129: 87-96. PMID 187575 |
0.114 |
|
| 2001 |
Qiao L, Leach K, McKinstry R, Gilfor D, Yacoub A, Park JS, Grant S, Hylemon PB, Fisher PB, Dent P. Hepatitis B virus X protein increases expression of p21Cip-1/WAF1/MDA6 and p27Kip-1 in primary mouse hepatocytes, leading to reduced cell cycle progression Hepatology. 34: 906-917. PMID 11679961 DOI: 10.1053/Jhep.2001.28886 |
0.112 |
|
| 1988 |
Gopal-Srivastava R, Hylemon PB. Purification and characterization of bile salt hydrolase from Clostridium perfringens Journal of Lipid Research. 29: 1079-1085. PMID 2903208 |
0.106 |
|
| 2003 |
Leach JK, Qiao L, Fang Y, Han SL, Gilfor D, Fisher PB, Grant S, Hylemon PB, Peterson D, Dent P. Regulation of p21 and p27 expression by the hepatitis B virus X protein and the alternate initiation site X proteins, AUG2 and AUG3. Journal of Gastroenterology and Hepatology. 18: 376-85. PMID 12653885 DOI: 10.1046/J.1440-1746.2003.02990.X |
0.103 |
|
| 1982 |
Glass TL, Winter J, Bokkenheuser VD, Hylemon PB. Biotransformation of 16α-hydroxyprogesterone by Eubacterium sp. 144: Non-enzymatic addition of L-cysteine to delta16-progesterone Journal of Lipid Research. 23: 352-356. PMID 7077150 |
0.103 |
|
| 1988 |
Roberts I, Hylemon PB, Holmes WM. Isolation of promoters from two anaerobic bacteria Microbios. 54: 87-99. PMID 2459583 |
0.101 |
|
| 1977 |
Hylemon PB, Young JL, Roadcap RF, Phibbs PV. Uptake and incorporation of glucose and mannose by whole cells of Bacteroides thetaiotaomicron. Applied and Environmental Microbiology. 34: 488-94. PMID 73363 |
0.101 |
|
| 2003 |
Lombard C, McKallip RJ, Hylemon PB, Nagarkatti PS, Nagarkatti M. Fas Ligand-dependent and -independent mechanisms of toxicity induced by T cell lymphomas in lymphoid organs and in the liver Clinical Immunology. 109: 144-153. PMID 14597213 DOI: 10.1016/S1521-6616(03)00179-7 |
0.096 |
|
| 2016 |
Bajaj J, Sterling R, Hylemon P, Nixon D, Heuman D, SIkaroodi M, Gillevet P. Chronic Opioid Therapy is Associated with Gut Dysbiosis in Cirrhosis Independent of Cirrhosis Severity Journal of Hepatology. 64: S446-S447. DOI: 10.1016/S0168-8278(16)00740-6 |
0.085 |
|
| 2008 |
Park MA, Zhang G, Martin AP, Hamed H, Mitchell C, Hylemon PB, Graf M, Rahmani M, Ryan K, Liu X, Spiegel S, Norris J, Fisher PB, Grant S, Dent P. Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation. Cancer Biology & Therapy. 7: 1648-62. PMID 18787411 DOI: 10.4161/Cbt.7.10.6623 |
0.078 |
|
| 1975 |
Hylemon PB, Sherrod JA. Multiple forms of 7 α hydroxysteroid dehydrogenase in selected strains of Bacteroides fragilis Journal of Bacteriology. 122: 418-424. PMID 236279 DOI: 10.1128/jb.122.2.418-424.1975 |
0.073 |
|
| 1978 |
Stellwag EJ, Hylemon PB. Characterization of 7-α-dehydroxylase in Clostridium leptum American Journal of Clinical Nutrition. 31. PMID 707382 DOI: 10.1093/ajcn/31.10.S243 |
0.072 |
|
| 2016 |
Bajaj JS, Betrapally NS, Hylemon PB, Thacker LR, Daita K, Kang DJ, White MB, Unser AB, Fagan A, Gavis EA, Sikaroodi M, Dalmet S, Heuman DM, Gillevet PM. Erratum: Gut Microbiota Alterations can predict Hospitalizations in Cirrhosis Independent of Diabetes Mellitus. Scientific Reports. 6: 20447. PMID 26823047 DOI: 10.1038/srep20447 |
0.071 |
|
| 2007 |
Dent P, Hylemon PB, Grant S, Fisher PB. Approaches for monitoring signal transduction changes in normal and cancer cells Methods in Molecular Biology (Clifton, N.J.). 383: 259-276. PMID 18217691 DOI: 10.1007/978-1-59745-335-6_17 |
0.067 |
|
| 1973 |
Hylemon PB, Wells JS, Krieg NR, Jannasch HW. The genus Spirillum: A taxonomic study International Journal of Systematic Bacteriology. 23: 340-380. |
0.061 |
|
| 1983 |
Sugerman HJ, Tatum JL, Hirsch JI, Sharp DE, Qureshi GD, Hylemon PB. Gamma Scintigraphic Localization of Platelets Labeled With Indium 111 in a Focus of Infection Archives of Surgery. 118: 185-189. PMID 6849636 DOI: 10.1001/archsurg.1983.01390020041007 |
0.056 |
|
| 2020 |
Kakiyama G, Marques D, Martin R, Takei H, Rodriguez-Agudo D, LaSalle SA, Hashiguchi T, Liu X, Green R, Erickson S, Gil G, Fuchs M, Suzuki M, Murai T, Nittono H, ... Hylemon PB, et al. Insulin resistance dysregulates CYP7B1 leading to oxysterol accumulation: a pathway for NAFL to NASH transition. Journal of Lipid Research. 61: 1629-1644. PMID 33455708 DOI: 10.1194/jlr.RA120000924 |
0.051 |
|
| 1974 |
Hylemon PB, Krieg NR, Phibbs PV. Transport and catabolism of D fructose by Spirillum itersonii Journal of Bacteriology. 117: 144-150. PMID 4808897 |
0.029 |
|
| 1973 |
Hylemon PB, Wells JS, Bowdre JH. Designation of Spirillum volutans Ehrenberg 1832 as type species of the genus Spirillum Ehrenberg 1832 and designation of the neotype strain of S. volutans. Request for an opinion International Journal of Systematic Bacteriology. 23: 20-27. |
0.022 |
|
| 2015 |
Hylemon P, Nagahashi M, Takabe K, Zhou H. Reply. Hepatology (Baltimore, Md.). 63: 1740-1. PMID 26121965 DOI: 10.1002/HEP.27961 |
0.01 |
|
| 2015 |
Bajaj JS, Zhou H, Joong Kang D, Hylemon PB. Reply. Hepatology (Baltimore, Md.). PMID 26105621 DOI: 10.1002/hep.27952 |
0.01 |
|
| 1976 |
Krieg NR, Hylemon PB. The taxonomy of the chemoheterotrophic spirilla Annual Review of Microbiology. 30: 303-325. PMID 791070 |
0.01 |
|
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