Year |
Citation |
Score |
2021 |
Zappasodi R, Serganova I, Cohen IJ, Maeda M, Shindo M, Senbabaoglu Y, Watson MJ, Leftin A, Maniyar R, Verma S, Lubin M, Ko M, Mane MM, Zhong H, Liu C, ... ... Koutcher JA, et al. CTLA-4 blockade drives loss of T stability in glycolysis-low tumours. Nature. PMID 33588426 DOI: 10.1038/s41586-021-03326-4 |
0.383 |
|
2020 |
Mane MM, Cohen IJ, Ackerstaff E, Shalaby K, Ijoma JN, Ko M, Maeda M, Albeg AS, Vemuri K, Satagopan J, Moroz A, Zurita J, Shenker L, Shindo M, Nickles T, ... ... Koutcher JA, et al. Lactate Dehydrogenase A Depletion Alters MyC-CaP Tumor Metabolism, Microenvironment, and CAR T Cell Therapy. Molecular Therapy Oncolytics. 18: 382-395. PMID 32913888 DOI: 10.1016/J.Omto.2020.07.006 |
0.456 |
|
2020 |
Frost GR, Longo V, Li T, Jonas LA, Judenhofer M, Cherry S, Koutcher J, Lekaye C, Zanzonico P, Li YM. Hybrid PET/MRI enables high-spatial resolution, quantitative imaging of amyloid plaques in an Alzheimer's disease mouse model. Scientific Reports. 10: 10379. PMID 32587315 DOI: 10.1038/S41598-020-67284-Z |
0.303 |
|
2020 |
Serganova I, Vemuri K, Cohen I, Lubin M, Roberts S, Maeda M, Mane M, Mann H, Reiner T, Chan E, Yarilin D, Manova-Todorova K, Zappasodi R, Merghoub T, Koutcher J, et al. Abstract 1476: Vessel normalization following LDH-A knockdown in murine breast tumors Tumor Biology. DOI: 10.1158/1538-7445.Am2020-1476 |
0.414 |
|
2019 |
Mane MM, Shalaby K, Cohen I, Albeg A, Ijoma J, Ko M, Maeda M, Vemuri K, Satagopan J, Moroz A, Zurita J, Shenker L, Ackerstaff E, Shindo M, Moroz E, ... ... Koutcher J, et al. Abstract A089: The effect of lactate dehydrogenase-A (LDH-A) knockdown and human prostate-specific membrane antigen (hPSMA) directed CAR T-cell treatment on hPSMA(+) Myc-CaP tumors Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-A089 |
0.51 |
|
2018 |
Bodo S, Campagne C, Thin TH, Higginson DS, Vargas HA, Hua G, Fuller JD, Ackerstaff E, Russell J, Zhang Z, Klingler S, Cho H, Kaag MG, Mazaheri Y, Rimner A, ... ... Koutcher JA, et al. Single-dose radiotherapy disables tumor cell homologous recombination via ischemia/reperfusion injury. The Journal of Clinical Investigation. PMID 30480549 DOI: 10.1172/Jci97631 |
0.389 |
|
2018 |
Serganova I, Cohen IJ, Vemuri K, Shindo M, Maeda M, Mane M, Moroz E, Khanin R, Satagopan J, Koutcher JA, Blasberg R. LDH-A regulates the tumor microenvironment via HIF-signaling and modulates the immune response. Plos One. 13: e0203965. PMID 30248111 DOI: 10.1371/journal.pone.0203965 |
0.402 |
|
2017 |
Patel BB, Ackerstaff E, Serganova IS, Kerrigan JE, Blasberg RG, Koutcher JA, Banerjee D. Tumor stroma interaction is mediated by monocarboxylate metabolism. Experimental Cell Research. PMID 28132882 DOI: 10.1016/j.yexcr.2017.01.013 |
0.414 |
|
2016 |
Cho H, Ackerstaff E, Carlin S, Lupu ME, Wang Y, Rizwan A, O'Donoghue J, Ling CC, Humm JL, Zanzonico PB, Koutcher JA. Corrigendum to "Noninvasive Multimodality Imaging of the Tumor Microenvironment: Registered Dynamic Magnetic Resonance Imaging and Positron Emission Tomography Studies of a Preclinical Tumor Model of Tumor Hypoxia" [Neoplasia 11 (2009) 247-259]. Neoplasia (New York, N.Y.). 18: 811. PMID 27978998 DOI: 10.1016/J.Neo.2016.10.008 |
0.711 |
|
2015 |
Sun X, Ackerstaff E, He F, Xing L, Hsiao HT, Koutcher JA, Ling CC, Li GC. Visualizing the antivascular effect of bortezomib on the hypoxic tumor microenvironment. Oncotarget. PMID 26416246 DOI: 10.18632/oncotarget.5300 |
0.416 |
|
2014 |
Viola-Villegas NT, Carlin SD, Ackerstaff E, Sevak KK, Divilov V, Serganova I, Kruchevsky N, Anderson M, Blasberg RG, Andreev OA, Engelman DM, Koutcher JA, Reshetnyak YK, Lewis JS. Understanding the pharmacological properties of a metabolic PET tracer in prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 111: 7254-9. PMID 24785505 DOI: 10.1073/Pnas.1405240111 |
0.387 |
|
2014 |
Bokacheva L, Ackerstaff E, LeKaye HC, Zakian K, Koutcher JA. High-field small animal magnetic resonance oncology studies. Physics in Medicine and Biology. 59: R65-R127. PMID 24374985 DOI: 10.1088/0031-9155/59/2/R65 |
0.329 |
|
2013 |
Rizwan A, Serganova I, Khanin R, Karabeber H, Ni X, Thakur S, Zakian KL, Blasberg R, Koutcher JA. Relationships between LDH-A, lactate, and metastases in 4T1 breast tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 5158-69. PMID 23833310 DOI: 10.1158/1078-0432.Ccr-12-3300 |
0.661 |
|
2013 |
Han SH, Ackerstaff E, Stoyanova R, Carlin S, Huang W, Koutcher JA, Kim JK, Cho G, Jang G, Cho H. Gaussian mixture model-based classification of dynamic contrast enhanced MRI data for identifying diverse tumor microenvironments: preliminary results. Nmr in Biomedicine. 26: 519-32. PMID 23440683 DOI: 10.1002/nbm.2888 |
0.4 |
|
2013 |
Bokacheva L, Kotedia K, Reese M, Ricketts SA, Halliday J, Le CH, Koutcher JA, Carlin S. Response of HT29 colorectal xenograft model to cediranib assessed with 18 F-fluoromisonidazole positron emission tomography, dynamic contrast-enhanced and diffusion-weighted MRI. Nmr in Biomedicine. 26: 151-63. PMID 22777834 DOI: 10.1002/Nbm.2830 |
0.372 |
|
2012 |
Stoyanova R, Huang K, Sandler K, Cho H, Carlin S, Zanzonico PB, Koutcher JA, Ackerstaff E. Mapping Tumor Hypoxia In Vivo Using Pattern Recognition of Dynamic Contrast-enhanced MRI Data. Translational Oncology. 5: 437-47. PMID 23326621 DOI: 10.1593/Tlo.12319 |
0.421 |
|
2012 |
Rattigan YI, Patel BB, Ackerstaff E, Sukenick G, Koutcher JA, Glod JW, Banerjee D. Lactate is a mediator of metabolic cooperation between stromal carcinoma associated fibroblasts and glycolytic tumor cells in the tumor microenvironment. Experimental Cell Research. 318: 326-35. PMID 22178238 DOI: 10.1016/j.yexcr.2011.11.014 |
0.399 |
|
2012 |
Yaligar J, Thakur SB, Bokacheva L, Carlin S, Thaler HT, Rizwan A, Lupu ME, Wang Y, Matei CC, Zakian KL, Koutcher JA. Lactate MRSI and DCE MRI as surrogate markers of prostate tumor aggressiveness. Nmr in Biomedicine. 25: 113-22. PMID 21618306 DOI: 10.1002/Nbm.1723 |
0.698 |
|
2012 |
Jansen JF, Schöder H, Lee NY, Stambuk HE, Wang Y, Fury MG, Patel SG, Pfister DG, Shah JP, Koutcher JA, Shukla-Dave A. Tumor metabolism and perfusion in head and neck squamous cell carcinoma: pretreatment multimodality imaging with 1H magnetic resonance spectroscopy, dynamic contrast-enhanced MRI, and [18F]FDG-PET. International Journal of Radiation Oncology, Biology, Physics. 82: 299-307. PMID 21236594 DOI: 10.1016/J.Ijrobp.2010.11.022 |
0.303 |
|
2012 |
Rizwan A, Serganova I, Ni X, Thakur S, Zakian KL, Blasberg R, Koutcher J. Abstract 3223: Magnetic resonance spectroscopic imaging of lactate in LDH-A silenced metastatic breast tumors Cancer Research. 72: 3223-3223. DOI: 10.1158/1538-7445.Am2012-3223 |
0.734 |
|
2011 |
Darpolor MM, Kennealey PT, Le HC, Zakian KL, Ackerstaff E, Rizwan A, Chen JH, Sambol EB, Schwartz GK, Singer S, Koutcher JA. Preclinical study of treatment response in HCT-116 cells and xenografts with (1) H-decoupled (31) P MRS. Nmr in Biomedicine. 24: 1159-68. PMID 21994185 DOI: 10.1002/Nbm.1674 |
0.619 |
|
2011 |
Serganova I, Rizwan A, Ni X, Thakur SB, Vider J, Russell J, Blasberg R, Koutcher JA. Metabolic imaging: a link between lactate dehydrogenase A, lactate, and tumor phenotype. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 6250-61. PMID 21844011 DOI: 10.1158/1078-0432.Ccr-11-0397 |
0.687 |
|
2011 |
Gade TP, Motley MW, Beattie BJ, Bhakta R, Boskey AL, Koutcher JA, Mayer-Kuckuk P. Imaging of alkaline phosphatase activity in bone tissue. Plos One. 6: e22608. PMID 21799916 DOI: 10.1371/Journal.Pone.0022608 |
0.561 |
|
2011 |
Patel BB, Rattigan YI, Ackerstaff E, Sukenick G, Glod JW, Koutcher J, Banerjee D. Abstract LB-287: Adaptive exploitation of stromal cell metabolism by tumor cells Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-287 |
0.518 |
|
2011 |
Patel B, Rattigan Y, Ackerstaff E, Koutcher J, Sukenick G, Glod J, Banerjee D. P1-03-03: Adaptive Exploitation of Stromal Cell Metabolism by Tumor Cells. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-P1-03-03 |
0.517 |
|
2010 |
Jansen JF, Schöder H, Lee NY, Wang Y, Pfister DG, Fury MG, Stambuk HE, Humm JL, Koutcher JA, Shukla-Dave A. Noninvasive assessment of tumor microenvironment using dynamic contrast-enhanced magnetic resonance imaging and 18F-fluoromisonidazole positron emission tomography imaging in neck nodal metastases. International Journal of Radiation Oncology, Biology, Physics. 77: 1403-10. PMID 19906496 DOI: 10.1016/j.ijrobp.2009.07.009 |
0.36 |
|
2010 |
He F, Sun X, Ackerstaff E, Xing L, Minami A, Hsiao HT, Carlin S, Ling CC, Koutcher J, Li GC. Abstract 1381: The effect of proteasome inhibitor velcade on tumor microenvironment Cancer Research. 70: 1381-1381. DOI: 10.1158/1538-7445.Am10-1381 |
0.456 |
|
2010 |
Stoyanova R, Ackerstaff E, Cho H, Koutcher J, Pollack A. DCE-MRI for Delineation of Hypoxic Regions in Prostate Tumors International Journal of Radiation Oncology*Biology*Physics. 78: S337. DOI: 10.1016/J.IJROBP.2010.07.799 |
0.31 |
|
2009 |
Lee N, Jensen J, Schoder H, Wang Y, Fury M, Pfister DG, Stambuk H, Humm J, Koutcher J, Shukla-Dave A. Correlation of dynamic contrast enhanced magnetic resonance imaging (DCE MRI) with (18)f-fluoromisonidazole positron emission and computed tomography ((18)F-FMISO PET/CT) in assessing tumor hypoxia in a series of head and neck cancer (HNC) patients with nodal metastases. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 6083. PMID 27961949 DOI: 10.1200/Jco.2009.27.15_Suppl.6083 |
0.415 |
|
2009 |
Le HC, Lupu M, Kotedia K, Rosen N, Solit D, Koutcher JA. Proton MRS detects metabolic changes in hormone sensitive and resistant human prostate cancer models CWR22 and CWR22r Magnetic Resonance in Medicine. 62: 1112-1119. PMID 19780165 DOI: 10.1002/mrm.22137 |
0.319 |
|
2009 |
Yang KM, Russell J, Lupu ME, Cho H, Li XF, Koutcher JA, Ling CC. Atrasentan (ABT-627) enhances perfusion and reduces hypoxia in a human tumor xenograft model. Cancer Biology & Therapy. 8: 1940-6. PMID 19717985 DOI: 10.4161/cbt.8.20.9595 |
0.371 |
|
2009 |
Mazaheri Y, Hricak H, Fine SW, Akin O, Shukla-Dave A, Ishill NM, Moskowitz CS, Grater JE, Reuter VE, Zakian KL, Touijer KA, Koutcher JA. Prostate tumor volume measurement with combined T2-weighted imaging and diffusion-weighted MR: correlation with pathologic tumor volume. Radiology. 252: 449-57. PMID 19703883 DOI: 10.1148/Radiol.2523081423 |
0.334 |
|
2009 |
Silberhumer GR, Zakian K, Malhotra S, Brader P, Gönen M, Koutcher J, Fong Y. Relationship between 31P metabolites and oncolytic viral therapy sensitivity in human colorectal cancer xenografts British Journal of Surgery. 96: 809-816. PMID 19526622 DOI: 10.1002/Bjs.6604 |
0.306 |
|
2009 |
Thakur SB, Yaligar J, Koutcher JA. In vivo lactate signal enhancement using binomial spectral-selective pulses in selective MQ coherence (SS-SelMQC) spectroscopy Magnetic Resonance in Medicine. 62: 591-598. PMID 19526486 DOI: 10.1002/mrm.22065 |
0.333 |
|
2009 |
Hernando E, Sarmentero-Estrada J, Koppie T, Belda-Iniesta C, Ramírez de Molina V, Cejas P, Ozu C, Le C, Sánchez JJ, González-Barón M, Koutcher J, Cordón-Cardó C, Bochner BH, Lacal JC, Ramírez de Molina A. A critical role for choline kinase-alpha in the aggressiveness of bladder carcinomas. Oncogene. 28: 2425-35. PMID 19448670 DOI: 10.1038/Onc.2009.91 |
0.442 |
|
2009 |
Cho H, Ackerstaff E, Carlin S, Lupu ME, Wang Y, Rizwan A, O'Donoghue J, Ling CC, Humm JL, Zanzonico PB, Koutcher JA. Noninvasive multimodality imaging of the tumor microenvironment: registered dynamic magnetic resonance imaging and positron emission tomography studies of a preclinical tumor model of tumor hypoxia. Neoplasia (New York, N.Y.). 11: 247-59, 2p following. PMID 19242606 DOI: 10.1593/Neo.81360 |
0.684 |
|
2009 |
Gade TP, Buchanan IM, Motley MW, Mazaheri Y, Spees WM, Koutcher JA. Imaging intratumoral convection: pressure-dependent enhancement in chemotherapeutic delivery to solid tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 247-55. PMID 19118052 DOI: 10.1158/1078-0432.CCR-08-0611 |
0.647 |
|
2009 |
Sun X, He F, Ackerstaff E, Xing L, Minami A, Carlin S, Ling C, Koutcher J, Li G. The Effect of Proteasome Inhibitor Velcade on Tumor Microenvironment International Journal of Radiation Oncology*Biology*Physics. 75: S171. DOI: 10.1016/J.Ijrobp.2009.07.398 |
0.462 |
|
2008 |
Zhang M, Huang M, Le C, Zanzonico PB, Claus F, Kolbert KS, Martin K, Ling CC, Koutcher JA, Humm JL. Accuracy and reproducibility of tumor positioning during prolonged and multi-modality animal imaging studies. Physics in Medicine and Biology. 53: 5867-82. PMID 18827321 DOI: 10.1088/0031-9155/53/20/021 |
0.344 |
|
2008 |
Gade TP, Koutcher JA, Spees WM, Beattie BJ, Ponomarev V, Doubrovin M, Buchanan IM, Beresten T, Zakian KL, Le HC, Tong WP, Mayer-Kuckuk P, Blasberg RG, Gelovani JG. Imaging transgene activity in vivo. Cancer Research. 68: 2878-84. PMID 18413756 DOI: 10.1158/0008-5472.Can-07-6028 |
0.562 |
|
2008 |
Huang M, Zhang M, Chang J, Le C, Zanzonico P, Humm J, Koutcher J, Ling C. TU-D-332-08: Gd-DTPA DCE-MRI Assisted Image-Guided PO2 Measurements in Rodent Tumor Xenografts Medical Physics. 35: 2907-2907. DOI: 10.1118/1.2962599 |
0.433 |
|
2008 |
Huang M, Zhang M, Chang J, Le C, Zanzonico P, Humm J, Koutcher J, Ling C. TU-D-332-01: Mapping of Viable Tumor Regions Using Gd-DTPA DCE-MRI Medical Physics. 35: 2905-2906. DOI: 10.1118/1.2962592 |
0.504 |
|
2008 |
Zhang M, Huang M, Le C, Zanzonico P, Claus F, Kolbert K, Martin K, Ling C, Koutcher J, Humm J. TU-C-332-07: Accuracy and Reproducibility of Tumor Position During Prolonged and Multi-Modality Animal Imaging Studies Medical Physics. 35: 2895-2895. DOI: 10.1118/1.2962526 |
0.435 |
|
2007 |
Procissi D, Claus F, Burgman P, Koziorowski J, Chapman JD, Thakur SB, Matei C, Ling CC, Koutcher JA. In vivo 19F magnetic resonance spectroscopy and chemical shift imaging of tri-fluoro-nitroimidazole as a potential hypoxia reporter in solid tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 3738-47. PMID 17575240 DOI: 10.1158/1078-0432.CCR-06-1563 |
0.314 |
|
2007 |
Dave A, Fury M, Lee N, Stambuk H, Wang Y, Karimi S, Pfister D, Koutcher J. Dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) as a predictor of response in head and neck squamous cell carcinoma (HNSCC) Journal of Clinical Oncology. 25: 6007-6007. DOI: 10.1200/Jco.2007.25.18_Suppl.6007 |
0.411 |
|
2006 |
Muruganandham M, Lupu M, Dyke JP, Matei C, Linn M, Packman K, Kolinsky K, Higgins B, Koutcher JA. Preclinical evaluation of tumor microvascular response to a novel antiangiogenic/antitumor agent RO0281501 by dynamic contrast-enhanced MRI at 1.5 T. Molecular Cancer Therapeutics. 5: 1950-7. PMID 16928815 DOI: 10.1158/1535-7163.MCT-06-0010 |
0.393 |
|
2006 |
Thakur SB, Karimi S, Dunkel IJ, Koutcher JA, Huang W. Longitudinal MR spectroscopic imaging of pediatric diffuse pontine tumors to assess tumor aggression and progression. Ajnr. American Journal of Neuroradiology. 27: 806-9. PMID 16611768 |
0.381 |
|
2006 |
Chang J, Thakur S, Perera G, Kowalski A, Huang W, Karimi S, Hunt M, Koutcher J, Fuks Z, Amols H, Narayana A. Image-fusion of MR spectroscopic images for treatment planning of gliomas. Medical Physics. 33: 32-40. PMID 16485406 DOI: 10.1016/J.Ijrobp.2004.06.179 |
0.386 |
|
2005 |
Gade TP, Hassen W, Santos E, Gunset G, Saudemont A, Gong MC, Brentjens R, Zhong XS, Stephan M, Stefanski J, Lyddane C, Osborne JR, Buchanan IM, Hall SJ, Heston WD, ... ... Koutcher JA, et al. Targeted elimination of prostate cancer by genetically directed human T lymphocytes. Cancer Research. 65: 9080-8. PMID 16204083 DOI: 10.1158/0008-5472.Can-05-0436 |
0.609 |
|
2005 |
Mayer-Kuckuk P, Gade TP, Buchanan IM, Doubrovin M, Ageyeva L, Bertino JR, Boskey AL, Blasberg RG, Koutcher JA, Banerjee D. High-resolution imaging of bone precursor cells within the intact bone marrow cavity of living mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 33-41. PMID 15963918 DOI: 10.1016/J.Ymthe.2005.02.018 |
0.535 |
|
2005 |
Muruganandham M, Alfieri AA, Matei C, Chen Y, Sukenick G, Schemainda I, Hasmann M, Saltz LB, Koutcher JA. Metabolic signatures associated with a NAD synthesis inhibitor-induced tumor apoptosis identified by 1H-decoupled-31P magnetic resonance spectroscopy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 3503-13. PMID 15867253 DOI: 10.1158/1078-0432.CCR-04-1399 |
0.365 |
|
2005 |
Spees WM, Gade TPF, Yang G, Tong WP, Bornmann WG, Gorlick R, Koutcher JA. An 19F magnetic resonance-based in vivo assay of solid tumor methotrexate resistance: Proof of principle Clinical Cancer Research. 11: 1454-1461. PMID 15746046 DOI: 10.1158/1078-0432.Ccr-04-1439 |
0.307 |
|
2005 |
Lewis BC, Klimstra DS, Socci ND, Xu S, Koutcher JA, Varmus HE. The absence of p53 promotes metastasis in a novel somatic mouse model for hepatocellular carcinoma. Molecular and Cellular Biology. 25: 1228-37. PMID 15684377 DOI: 10.1128/Mcb.25.4.1228-1237.2005 |
0.352 |
|
2004 |
Martin DS, Alfieri A, Koutcher J, Fantin V, Spriggs D, Norton L. Efficacy of a mitochondrial toxin, F16, in a multi-ATP-depleting regimen + chemotherapy on human breast cancer (MDA-MB-468) xenografts. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 22: 2096. PMID 28016765 DOI: 10.1200/Jco.2004.22.90140.2096 |
0.393 |
|
2004 |
Shih AH, Dai C, Hu X, Rosenblum MK, Koutcher JA, Holland EC. Dose-dependent effects of platelet-derived growth factor-B on glial tumorigenesis. Cancer Research. 64: 4783-9. PMID 15256447 DOI: 10.1158/0008-5472.CAN-03-3831 |
0.382 |
|
2004 |
Gade TP, Spees WM, Le HC, Zakian KL, Ponomarev V, Doubrovin M, Gelovani JG, Koutcher JA. In vivo 5-fluorouracil and fluoronucleotide T1 relaxation time measurements using the variable nutation angle method. Magnetic Resonance in Medicine. 52: 169-73. PMID 15236381 DOI: 10.1002/Mrm.20131 |
0.608 |
|
2004 |
Dupont J, Schwartz L, Koutcher J, Spriggs D, Gordon M, Mendelson D, Murren J, Lucarelli A, Cedarbaum J. 132 A phase I and pharmacokinetic clinical trial of subcutaneous (sc) VEGF trap in advanced solid tumor patients European Journal of Cancer Supplements. 2: 43. DOI: 10.1016/S1359-6349(04)80140-X |
0.355 |
|
2004 |
Narayana A, Chang J, Thakur S, Huang W, Kowalski A, Perera G, Karimi S, Holodny A, Hunt M, Amols H, Koutcher J, Leibel SA. Use of MR spectroscopy and functional imaging in the treatment planning of gliomas International Journal of Radiation Oncology Biology Physics. 60. DOI: 10.1016/J.Ijrobp.2004.06.178 |
0.313 |
|
2003 |
Spees WM, Yang G, Veach D, Rubio MB, Koutcher JA, Bornmann W. A fluorine-labeled methotrexate as a probe for monitoring tumor antifolate pharmacokinetics: synthesis, in vitro cytotoxicity, and pilot in vivo 19F magnetic resonance spectra. Molecular Cancer Therapeutics. 2: 933-9. PMID 14578458 |
0.306 |
|
2003 |
Dyke JP, Zakian KL, Spees WM, Matei C, Chen Y, Mao X, Shungu DC, Koutcher JA. Metabolic response of the CWR22 prostate tumor xenograft after 20 Gy of radiation studied by 1H spectroscopic imaging. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 4529-36. PMID 14555527 |
0.314 |
|
2003 |
Humm JL, Ballon D, Hu YC, Ruan S, Chui C, Tulipano PK, Erdi A, Koutcher J, Zakian K, Urano M, Zanzonico P, Mattis C, Dyke J, Chen Y, Harrington P, et al. A stereotactic method for the three-dimensional registration of multi-modality biologic images in animals: NMR, PET, histology, and autoradiography. Medical Physics. 30: 2303-14. PMID 14528951 DOI: 10.1118/1.1600738 |
0.482 |
|
2003 |
Kikuchi E, Xu S, Ohori M, Matei C, Lupu M, Menendez S, Koutcher JA, Bochner BH. Detection and quantitative analysis of early stage orthotopic murine bladder tumor using in vivo magnetic resonance imaging. The Journal of Urology. 170: 1375-8. PMID 14501772 DOI: 10.1097/01.ju.0000075504.13456.41 |
0.404 |
|
2003 |
Doubrovin M, Ponomarev V, Serganova I, Soghomonian S, Myagawa T, Beresten T, Ageyeva L, Sadelain M, Koutcher J, Blasberg RG, Gelovani Tjuvajev JG. Development of a new reporter gene system-dsRed/Xanthine phosphoribosyltransferase-xanthine for molecular imaging of processes behind the intact blood-brain barrier Molecular Imaging. 2: 93-112. PMID 12964307 DOI: 10.1162/153535003322331984 |
0.372 |
|
2003 |
Dyke JP, Panicek DM, Healey JH, Meyers PA, Huvos AG, Schwartz LH, Thaler HT, Tofts PS, Gorlick R, Koutcher JA, Ballon D. Osteogenic and Ewing sarcomas: estimation of necrotic fraction during induction chemotherapy with dynamic contrast-enhanced MR imaging. Radiology. 228: 271-8. PMID 12832588 DOI: 10.1148/Radiol.2281011651 |
0.341 |
|
2003 |
Mayer-Kuckuk P, Doubrovin M, Gusani NJ, Gade T, Balatoni J, Akhurst T, Finn R, Fong Y, Koutcher JA, Larson S, Blasberg R, Tjuvajev JG, Bertino JR, Banerjee D. Imaging of dihydrofolate reductase fusion gene expression in xenografts of human liver metastases of colorectal cancer in living rats. European Journal of Nuclear Medicine and Molecular Imaging. 30: 1281-91. PMID 12664136 DOI: 10.1007/S00259-003-1143-Z |
0.624 |
|
2003 |
Xu S, Gade TP, Matei C, Zakian K, Alfieri AA, Hu X, Holland EC, Soghomonian S, Tjuvajev J, Ballon D, Koutcher JA. In vivo multiple-mouse imaging at 1.5 T. Magnetic Resonance in Medicine. 49: 551-7. PMID 12594759 DOI: 10.1002/mrm.10397 |
0.66 |
|
2002 |
Koutcher JA, Hu X, Xu S, Gade TP, Leeds N, Zhou XJ, Zagzag D, Holland EC. MRI of mouse models for gliomas shows similarities to humans and can be used to identify mice for preclinical trials. Neoplasia (New York, N.Y.). 4: 480-5. PMID 12407441 DOI: 10.1038/Sj.Neo.7900269 |
0.651 |
|
2002 |
Urano M, Chen Y, Humm J, Koutcher JA, Zanzonico P, Ling C. Measurements of tumor tissue oxygen tension using a time-resolved luminescence-based optical oxylite probe: comparison with a paired survival assay. Radiation Research. 158: 167-73. PMID 12105986 DOI: 10.1667/0033-7587(2002)158[0167:Mottot]2.0.Co;2 |
0.361 |
|
2001 |
Xu S, Zakian K, Thaler H, Matei C, Alfieri A, Chen Y, Koutcher JA. Effects of Motexafin gadolinium on tumor metabolism and radiation sensitivity International Journal of Radiation Oncology Biology Physics. 49: 1381-1390. PMID 11286846 DOI: 10.1016/S0360-3016(00)01566-2 |
0.389 |
|
2000 |
Evelhoch JL, Gillies RJ, Karczmar GS, Koutcher JA, Maxwell RJ, Nalcioglu O, Raghunand N, Ronen SM, Ross BD, Swartz HM. Applications of magnetic resonance in model systems: cancer therapeutics. Neoplasia (New York, N.Y.). 2: 152-65. PMID 10933074 DOI: 10.1038/Sj.Neo.7900078 |
0.43 |
|
2000 |
Koutcher JA, Motwani M, Zakian KL, Li XK, Matei C, Dyke JP, Ballon D, Yoo HH, Schwartz GK. The in vivo effect of bryostatin-1 on paclitaxel-induced tumor growth, mitotic entry, and blood flow. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 6: 1498-507. PMID 10778982 |
0.405 |
|
1999 |
Tjuvajev JG, Chen SH, Joshi A, Joshi R, Guo ZS, Balatoni J, Ballon D, Koutcher J, Finn R, Woo SL, Blasberg RG. Imaging adenoviral-mediated herpes virus thymidine kinase gene transfer and expression in vivo Cancer Research. 59: 5186-5193. PMID 10537296 |
0.356 |
|
1998 |
Tjuvajev JG, Avril N, Oku T, Sasajima T, Miyagawa T, Joshi R, Safer M, Beattie B, DiResta G, Daghighian F, Augensen F, Koutcher J, Zweit J, Humm J, Larson SM, et al. Imaging herpes virus thymidine kinase gene transfer and expression by positron emission tomography Cancer Research. 58: 4333-4341. PMID 9766661 |
0.4 |
|
1998 |
Tjuvajev J, Kolesnikov Y, Joshi R, Sherinski J, Koutcher L, Zhou Y, Matei C, Koutcher J, Kreek MJ, Blasberg R. Anti-neoplastic properties of human corticotropin releasing factor: involvement of the nitric oxide pathway. In Vivo (Athens, Greece). 12: 1-10. PMID 9575420 |
0.331 |
|
1997 |
Koutcher JA, Alfieri AA, Thaler H, Matei C, Martin DS. Radiation enhancement by biochemical modulation and 5-fluorouracil International Journal of Radiation Oncology Biology Physics. 39: 1145-1152. PMID 9392557 DOI: 10.1016/S0360-3016(97)00505-1 |
0.32 |
|
1997 |
Street JC, Szwergold BS, Matei C, Kappler F, Mahmood U, Brown TR, Koutcher JA. Study of the metabolism of choline and phosphatidylcholine in tumors in vivo using phosphonium-choline. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 38: 769-75. PMID 9358451 DOI: 10.1002/mrm.1910380513 |
0.356 |
|
1997 |
Nord LD, Stolfi RL, Alfieri AA, Netto G, Reuter V, Sternberg SS, Colofiore JR, Koutcher JA, Martin DS. Apoptosis induced in advanced CD8F1-murine mammary tumors by the combination of PALA, MMPR and 6AN precedes tumor regression and is preceded by ATP depletion. Cancer Chemotherapy and Pharmacology. 40: 376-84. PMID 9272113 DOI: 10.1007/s002800050674 |
0.368 |
|
1996 |
Koutcher JA, Alfieri AA, Matei C, Meyer KL, Street JC, Martin DS. Effect of 6-aminonicotinamide on the pentose phosphate pathway: 31P NMR and tumor growth delay studies Magnetic Resonance in Medicine. 36: 887-892. PMID 8946354 |
0.324 |
|
1996 |
Tjuvajev JG, Finn R, Watanabe K, Joshi R, Oku T, Kennedy J, Beattie B, Koutcher J, Larson S, Blasberg RG. Noninvasive imaging of herpes virus thymidine kinase gene transfer and expression: A potential method for monitoring clinical gene therapy Cancer Research. 56: 4087-4095. PMID 8797571 |
0.416 |
|
1995 |
Gerweck LE, Koutcher J, Zaidi ST. Energy status parameters, hypoxia fraction and radiocurability across tumor types Acta Oncologica. 34: 335-338. PMID 7779419 DOI: 10.3109/02841869509093985 |
0.464 |
|
1995 |
Tjuvajev J, Gansbacher B, Desai R, Beattie B, Kaplitt M, Matei C, Koutcher J, Gilboa E, Blasberg R. RG-2 glioma growth attenuation and severe brain edema caused by local production of interleukin-2 and interferon-gamma. Cancer Research. 55: 1902-10. PMID 7728757 |
0.332 |
|
1993 |
Tjuvajev J, Muraki A, Ginos J, Berk J, Koutcher J, Ballon D, Beattie B, Finn R, Blasberg RG. Iododeoxyuridine uptake and retention as a measure of tumor growth Journal of Nuclear Medicine. 34: 1152-1162. PMID 8315494 |
0.332 |
|
1992 |
Mahmood U, Devitt ML, Kocheril PG, Sutanto-Ward E, Ballon D, Sigurdson ER, Koutcher JA. Quantitation of total metastatic tumor volume in the rat liver: correlation of MR and histologic measurements. Journal of Magnetic Resonance Imaging : Jmri. 2: 335-40. PMID 1627869 DOI: 10.1002/Jmri.1880020314 |
0.424 |
|
1992 |
Gerweck LE, Koutcher JA, Syed Zaidi TH, Seneviratne T. Energy status in the murine FSaII and MCaIV tumors under aerobic and hypoxic conditions: An in-vivo and in-vitro analysis International Journal of Radiation Oncology, Biology, Physics. 23: 557-561. PMID 1612956 DOI: 10.1016/0360-3016(92)90011-6 |
0.358 |
|
1992 |
Koutcher JA, Alfieri AA, Devitt ML, Rhee JG, Kornblith AB, Mahmood U, Merchant TE, Cowburn D. Quantitative changes in tumor metabolism, partial pressure of oxygen, and radiobiological oxygenation status postradiation. Cancer Research. 52: 4620-7. PMID 1511430 |
0.394 |
|
1992 |
Merchant T, Alfieri A, Koutcher J. Comparison of quantitative changes in phosphatic metabolites and phospholipids with tumor re-oxygenation following irradiation International Journal of Radiation Oncology*Biology*Physics. 24: 236. DOI: 10.1016/0360-3016(92)90319-D |
0.315 |
|
1991 |
Koutcher JA, Sawyer RC, Kornblith AB, Stolfi RL, Martin DS, Devitt ML, Cowburn D, Young CW. In vivo monitoring of changes in 5-fluorouracil metabolism induced by methotrexate measured by 19F NMR spectroscopy. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 19: 113-23. PMID 2046526 DOI: 10.1002/Mrm.1910190111 |
0.599 |
|
1990 |
Koutcher JA, Barnett D, Kornblith AB, Cowburn D, Brady TJ, Gerweck LE. Relationship of changes in pH and energy status to hypoxic cell fraction and hyperthermia sensitivity International Journal of Radiation Oncology, Biology, Physics. 18: 1429-1435. PMID 2370193 DOI: 10.1016/0360-3016(90)90318-E |
0.618 |
|
1990 |
Koutcher JA, Alfieri AA, Barnett DC, Cowburn DC, Kornblith AB, Kim JH. Changes in 31P nuclear magnetic resonance with tumor growth in radioresistant and radiosensitive tumors Radiation Research. 121: 312-319. PMID 2315448 |
0.382 |
|
1990 |
Koutcher JA, Alfieri AA, Kornblith AB, Devitt ML, Cowburn D, Ballon D, Kim JH. Changes in radiation sensitization induced by Fluosol-DA as measured by 31P nuclear magnetic resonance spectroscopy. Cancer Research. 50: 7252-6. PMID 2121332 |
0.406 |
|
1990 |
Koutcher JA, Alfieri AA, Barnett DC, Cowburn DC, Kornblith AB, Kim JH. Changes in 31 P Nuclear Magnetic Resonance with Tumor Growth in Radioresistant and Radiosensitive Tumors Radiation Research. 121: 312. DOI: 10.2307/3577782 |
0.382 |
|
1989 |
Gerweck LE, Urano M, Koutcher J, Fellenz MP, Kahn J. Relationship between energy status, hypoxic cell fraction, and hyperthermic sensitivity in a murine fibrosarcoma Radiation Research. 117: 448-458. PMID 2928469 DOI: 10.2307/3577350 |
0.433 |
|
1987 |
Koutcher JA, Okunieff P, Neuringer L, Suit H, Brady T. Size dependent changes in tumor phosphate metabolism after radiation therapy as detected by 31P NMR spectroscopy International Journal of Radiation Oncology, Biology, Physics. 13: 1851-1855. PMID 3679923 DOI: 10.1016/0360-3016(87)90351-8 |
0.404 |
|
1987 |
Koutcher J, Alfieri A, Barnett D, Cowburn D, Fuks Z, Kim J. P NMR studies of a murine fibrosarcoma: Relationship of tumor size, pH and high energy phosphates with thermal sensitivity International Journal of Radiation Oncology*Biology*Physics. 13: 117-118. DOI: 10.1016/0360-3016(87)91076-5 |
0.539 |
|
1986 |
Okunieff PG, Koutcher JA, Gerweck L, Mcfarland E, Hitzig B, Urano M, Brady T, Neuringer L, Suit HD. Tumor size dependent changes in a murine fibrosarcoma: Use of in vivo 31P NMR for non-invasive evaluation of tumor metabolic status International Journal of Radiation Oncology, Biology, Physics. 12: 793-799. PMID 3710861 DOI: 10.1016/0360-3016(86)90038-6 |
0.432 |
|
1986 |
Okunieff P, Koutcher J, Brady T, Neuringer L, Suit HD, Phil D. Size dependent changes in tumor phosphate metabolism as detected by 31P NMR spectroscopy International Journal of Radiation Oncology*Biology*Physics. 12: 116. DOI: 10.1016/0360-3016(86)90552-3 |
0.414 |
|
1983 |
Koutcher JA, Goldsmith M. Nuclear magnetic resonance: Preclinical and clinical studies in tumor detection Critical Reviews in Oncology and Hematology. 1: 93-128. PMID 6397265 DOI: 10.1016/S1040-8428(83)80006-7 |
0.307 |
|
1978 |
Goldsmith M, Koutcher J, Damadian R. NMR in cancer. XI. Application of the NMR malignancy index to human gastro-intestinal tumors Cancer. 41: 183-191. PMID 626928 DOI: 10.1002/1097-0142(197801)41:1<183::Aid-Cncr2820410127>3.0.Co;2-1 |
0.332 |
|
1976 |
Damadian R, Minkoff L, Goldsmith M, Stanford M, Koutcher J. Field focusing nuclear magnetic resonance (FONAR): visualization of a tumor in a live animal Science. 194: 1430-1432. PMID 1006309 DOI: 10.1126/Science.1006309 |
0.461 |
|
1976 |
Damadian R, Minkoff L, Goldsmith M, Stanford M, Koutcher J. Tumor imaging in a live animal by focusing NMR (FONAR) Physiological Chemistry and Physics. 8: 61-65. PMID 959335 |
0.403 |
|
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