| Year |
Citation |
Score |
| 2022 |
Pillai S, Mahmud I, Mahar R, Griffith C, Langsen M, Nguyen J, Wojtkowiak JW, Swietach P, Gatenby RA, Bui MM, Merritt ME, McDonald P, Garrett TJ, Gillies RJ. Lipogenesis mediated by OGR1 regulates metabolic adaptation to acid stress in cancer cells via autophagy. Cell Reports. 39: 110796. PMID 35545051 DOI: 10.1016/j.celrep.2022.110796 |
0.322 |
|
| 2019 |
Pillai S, Langsen M, Nguyen J, Wojtkowiak J, Bui M, Gatenby R, Gillies R. Abstract 1846: Acid sensing G protein-coupled receptor OGR1 is required for acid induced adiposomogenesis in breast cancer cells Cancer Research. 79: 1846-1846. DOI: 10.1158/1538-7445.Sabcs18-1846 |
0.421 |
|
| 2017 |
McFarland C, Yaglom JA, Wojtkowiak JW, Scott J, Morse DL, Sherman MY, Mirny L. The damaging effect of passenger mutations on cancer progression. Cancer Research. PMID 28536279 DOI: 10.1158/0008-5472.Can-15-3283-T |
0.352 |
|
| 2017 |
Ibrahim-Hashim A, Robertson-Tessi M, Enrizues-Navas P, Damaghi M, Balagurunathan Y, Wojtkowiak JW, Russell S, Yoonseok K, Lloyd MC, Bui MM, Brown JS, Anderson AR, Gillies RJ, Gatenby RA. Defining cancer subpopulations by adaptive strategies rather than molecular properties provides novel insights into intratumoral evolution. Cancer Research. PMID 28249898 DOI: 10.1158/0008-5472.Can-16-2844 |
0.43 |
|
| 2017 |
Pillai S, Wojtkowiak JW, Damaghi M, Gatenby R, Gillies R. Abstract 3538: Enhanced dependence on lipid metabolism is a cellular adaptation to acidic microenvironment Cancer Research. 77: 3538-3538. DOI: 10.1158/1538-7445.Am2017-3538 |
0.408 |
|
| 2016 |
Zhang X, Wojtkowiak JW, Martinez GV, Cornnell HH, Hart CP, Baker AF, Gillies R. MR Imaging Biomarkers to Monitor Early Response to Hypoxia-Activated Prodrug TH-302 in Pancreatic Cancer Xenografts. Plos One. 11: e0155289. PMID 27227903 DOI: 10.1371/Journal.Pone.0155289 |
0.395 |
|
| 2016 |
Sewda K, Coppola D, Enkemann S, Yue B, Kim J, Lopez AS, Wojtkowiak JW, Stark VE, Morse B, Shibata D, Vignesh S, Morse DL. Cell-surface markers for colon adenoma and adenocarcinoma. Oncotarget. PMID 26894861 DOI: 10.18632/Oncotarget.7402 |
0.336 |
|
| 2015 |
Pilon-Thomas S, Kodumudi KN, El-Kenawi AE, Russell S, Weber AM, Luddy K, Damaghi M, Wojtkowiak JW, Mulé JJ, Ibrahim-Hashim A, Gillies RJ. Neutralization of tumor acidity improves antitumor responses to immunotherapeutic interventions. Cancer Research. PMID 26719539 DOI: 10.1158/0008-5472.Can-15-1743 |
0.451 |
|
| 2015 |
Damaghi M, Tafreshi NK, Lloyd MC, Sprung R, Estrella V, Wojtkowiak JW, Morse DL, Koomen JM, Bui MM, Gatenby RA, Gillies RJ. Chronic acidosis in the tumour microenvironment selects for overexpression of LAMP2 in the plasma membrane. Nature Communications. 6: 8752. PMID 26658462 DOI: 10.1038/Ncomms9752 |
0.386 |
|
| 2015 |
Enriquez-Navas PM, Wojtkowiak JW, Gatenby RA. Application of Evolutionary Principles to Cancer Therapy. Cancer Research. 75: 4675-80. PMID 26527288 DOI: 10.1158/0008-5472.Can-15-1337 |
0.417 |
|
| 2015 |
Wojtkowiak JW, Cornnell HC, Matsumoto S, Saito K, Takakusagi Y, Dutta P, Kim M, Zhang X, Leos R, Bailey KM, Martinez G, Lloyd MC, Weber C, Mitchell JB, Lynch RM, et al. Pyruvate sensitizes pancreatic tumors to hypoxia-activated prodrug TH-302. Cancer & Metabolism. 3: 2. PMID 25635223 DOI: 10.1186/S40170-014-0026-Z |
0.431 |
|
| 2015 |
Enriquez-Navas PM, Wojtkowiak J, Ruiz E, Hassan S, Gillies RJ, Gatenby RA. Abstract B11: Adaptive therapy modifies tumor vascularity Molecular Cancer Therapeutics. 14. DOI: 10.1158/1538-8514.Tumang15-B11 |
0.425 |
|
| 2014 |
Bailey KM, Cornnell HH, Ibrahim-Hashim A, Wojtkowiak JW, Hart CP, Zhang X, Leos R, Martinez GV, Baker AF, Gillies RJ. Evaluation of the "steal" phenomenon on the efficacy of hypoxia activated prodrug TH-302 in pancreatic cancer. Plos One. 9: e113586. PMID 25532146 DOI: 10.1371/Journal.Pone.0113586 |
0.413 |
|
| 2014 |
Takakusagi Y, Matsumoto S, Saito K, Matsuo M, Kishimoto S, Wojtkowiak JW, DeGraff W, Kesarwala AH, Choudhuri R, Devasahayam N, Subramanian S, Munasinghe JP, Gillies RJ, Mitchell JB, Hart CP, et al. Pyruvate induces transient tumor hypoxia by enhancing mitochondrial oxygen consumption and potentiates the anti-tumor effect of a hypoxia-activated prodrug TH-302. Plos One. 9: e107995. PMID 25254649 DOI: 10.1371/Journal.Pone.0107995 |
0.419 |
|
| 2014 |
Bailey KM, Wojtkowiak JW, Cornnell HH, Ribeiro MC, Balagurunathan Y, Hashim AI, Gillies RJ. Mechanisms of buffer therapy resistance. Neoplasia (New York, N.Y.). 16: 354-64.e1-3. PMID 24862761 DOI: 10.1016/J.Neo.2014.04.005 |
0.438 |
|
| 2013 |
Damaghi M, Wojtkowiak JW, Gillies RJ. pH sensing and regulation in cancer. Frontiers in Physiology. 4: 370. PMID 24381558 DOI: 10.3389/Fphys.2013.00370 |
0.304 |
|
| 2013 |
Rothberg JM, Bailey KM, Wojtkowiak JW, Ben-Nun Y, Bogyo M, Weber E, Moin K, Blum G, Mattingly RR, Gillies RJ, Sloane BF. Acid-mediated tumor proteolysis: contribution of cysteine cathepsins. Neoplasia (New York, N.Y.). 15: 1125-37. PMID 24204192 DOI: 10.1593/Neo.13946 |
0.692 |
|
| 2013 |
Agus DB, Alexander JF, Arap W, Ashili S, Aslan JE, Austin RH, Backman V, Bethel KJ, Bonneau R, Chen WC, Chen-Tanyolac C, Choi NC, Curley SA, Dallas M, ... ... Wojtkowiak J, et al. A physical sciences network characterization of non-tumorigenic and metastatic cells. Scientific Reports. 3: 1449. PMID 23618955 DOI: 10.1038/Srep01449 |
0.355 |
|
| 2013 |
Estrella V, Chen T, Lloyd M, Wojtkowiak J, Cornnell HH, Ibrahim-Hashim A, Bailey K, Balagurunathan Y, Rothberg JM, Sloane BF, Johnson J, Gatenby RA, Gillies RJ. Acidity generated by the tumor microenvironment drives local invasion. Cancer Research. 73: 1524-35. PMID 23288510 DOI: 10.1158/0008-5472.Can-12-2796 |
0.369 |
|
| 2013 |
Rejniak KA, Kim M, Wojtkowiak J, Gillies RJ. Abstract B49: The interplay between hypoxia-activated drugs and the microenvironment in pancreatic cancers: a computational study Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-B49 |
0.407 |
|
| 2013 |
Bailey KM, Wojtkowiak JW, Hashim AAI, Gillies RJ. Abstract 3941: Manipulating the tumor microenvironment for therapeutic benefit: identifying mechanisms of buffer resistance. Cancer Research. 73: 3941-3941. DOI: 10.1158/1538-7445.Am2013-3941 |
0.43 |
|
| 2012 |
Bailey KM, Wojtkowiak JW, Hashim AI, Gillies RJ. Targeting the metabolic microenvironment of tumors. Advances in Pharmacology (San Diego, Calif.). 65: 63-107. PMID 22959024 DOI: 10.1016/B978-0-12-397927-8.00004-X |
0.427 |
|
| 2012 |
Wojtkowiak JW, Gillies RJ. Autophagy on acid. Autophagy. 8: 1688-9. PMID 22874557 DOI: 10.4161/Auto.21501 |
0.478 |
|
| 2012 |
Wojtkowiak JW, Rothberg JM, Kumar V, Schramm KJ, Haller E, Proemsey JB, Lloyd MC, Sloane BF, Gillies RJ. Chronic autophagy is a cellular adaptation to tumor acidic pH microenvironments. Cancer Research. 72: 3938-47. PMID 22719070 DOI: 10.1158/0008-5472.Can-11-3881 |
0.451 |
|
| 2012 |
Sewda K, Wojtkowiak JW, Enkemann S, Lopez AS, Coppola D, Shibata D, Yeatman TJ, Gillies RJ, Morse DL. Abstract 1156: Cell-surface marker discovery for colorectal cancer Cancer Research. 72: 1156-1156. DOI: 10.1158/1538-7445.Am2012-1156 |
0.343 |
|
| 2011 |
Ibrahim-Hashim A, Wojtkowiak JW, de Lourdes Coelho Ribeiro M, Estrella V, Bailey KM, Cornnell HH, Gatenby RA, Gillies RJ. Free Base Lysine Increases Survival and Reduces Metastasis in Prostate Cancer Model. Journal of Cancer Science & Therapy. PMID 24032073 DOI: 10.4172/1948-5956.S1-004 |
0.426 |
|
| 2011 |
Wojtkowiak JW, Verduzco D, Schramm KJ, Gillies RJ. Drug resistance and cellular adaptation to tumor acidic pH microenvironment. Molecular Pharmaceutics. 8: 2032-8. PMID 21981633 DOI: 10.1021/Mp200292C |
0.396 |
|
| 2011 |
Hashim AI, Zhang X, Wojtkowiak JW, Martinez GV, Gillies RJ. Imaging pH and metastasis. Nmr in Biomedicine. 24: 582-91. PMID 21387439 DOI: 10.1002/Nbm.1644 |
0.406 |
|
| 2011 |
Wojtkowiak JW, Sane KM, Kleinman M, Sloane BF, Reiners JJ, Mattingly RR. Aborted autophagy and nonapoptotic death induced by farnesyl transferase inhibitor and lovastatin. The Journal of Pharmacology and Experimental Therapeutics. 337: 65-74. PMID 21228063 DOI: 10.1124/Jpet.110.174573 |
0.636 |
|
| 2011 |
Wojtkowiak JW, Barkey NM, Kumar V, Lloyd MC, Gatenby RA, Gillies RJ. Abstract 1254: Altered lipid and glucose metabolism is a cellular adaptation to tumor acidic microenvironments Cancer Research. 71: 1254-1254. DOI: 10.1158/1538-7445.Am2011-1254 |
0.418 |
|
| 2010 |
Sane KM, Mynderse M, Lalonde DT, Dean IS, Wojtkowiak JW, Fouad F, Borch RF, Reiners JJ, Gibbs RA, Mattingly RR. A novel geranylgeranyl transferase inhibitor in combination with lovastatin inhibits proliferation and induces autophagy in STS-26T MPNST cells. The Journal of Pharmacology and Experimental Therapeutics. 333: 23-33. PMID 20086055 DOI: 10.1124/Jpet.109.160192 |
0.646 |
|
| 2010 |
Schramm KJ, Vibet S, Oguz U, Wojtkowiak J, Koomen JM, Gillies RJ. Abstract A65: Changes in protein expression related to acidosis in the tumor microenvironment Cancer Epidemiology, Biomarkers & Prevention. 19. DOI: 10.1158/1055-9965.Disp-10-A65 |
0.402 |
|
| 2009 |
Wojtkowiak JW, Gibbs RA, Mattingly RR. Working together: Farnesyl transferase inhibitors and statins block protein prenylation. Molecular and Cellular Pharmacology. 1: 1-6. PMID 20419048 DOI: 10.4255/Mcpharmacol.09.01 |
0.704 |
|
| 2009 |
Wojtkowiak JW, Gibbs RA, Mattingly RR. Working together: Farnesyl transferase inhibitors and statins block protein prenylation Molecular and Cellular Pharmacology. 1: 1-6. DOI: 10.4255/mcpharmacol.09.01 |
0.618 |
|
| 2008 |
Dilworth JT, Wojtkowiak JW, Mathieu P, Tainsky MA, Reiners JJ, Mattingly RR, Hancock CN. Suppression of proliferation of two independent NF1 malignant peripheral nerve sheath tumor cell lines by the pan-ErbB inhibitor CI-1033. Cancer Biology & Therapy. 7: 1938-46. PMID 18927496 DOI: 10.4161/Cbt.7.12.6942 |
0.758 |
|
| 2008 |
Wojtkowiak JW, Fouad F, LaLonde DT, Kleinman MD, Gibbs RA, Reiners JJ, Borch RF, Mattingly RR. Induction of apoptosis in neurofibromatosis type 1 malignant peripheral nerve sheath tumor cell lines by a combination of novel farnesyl transferase inhibitors and lovastatin. The Journal of Pharmacology and Experimental Therapeutics. 326: 1-11. PMID 18367665 DOI: 10.1124/Jpet.107.135830 |
0.703 |
|
| 2007 |
Clark MK, Scott SA, Wojtkowiak J, Chirco R, Mathieu P, Reiners JJ, Mattingly RR, Borch RF, Gibbs RA. Synthesis, biochemical, and cellular evaluation of farnesyl monophosphate prodrugs as farnesyltransferase inhibitors. Journal of Medicinal Chemistry. 50: 3274-82. PMID 17555307 DOI: 10.1021/Jm0701829 |
0.711 |
|
| 2006 |
Dilworth JT, Kraniak JM, Wojtkowiak JW, Gibbs RA, Borch RF, Tainsky MA, Reiners JJ, Mattingly RR. Molecular targets for emerging anti-tumor therapies for neurofibromatosis type 1. Biochemical Pharmacology. 72: 1485-92. PMID 16797490 DOI: 10.1016/J.Bcp.2006.04.010 |
0.751 |
|
| Show low-probability matches. |