| Year |
Citation |
Score |
| 2022 |
Fong BC, Chakroun I, Iqbal MA, Paul S, Bastasic J, O'Neil D, Yakubovich E, Bejjani AT, Ahmadi N, Carter A, Clark A, Leone G, Park DS, Ghanem N, Vandenbosch R, et al. The Rb/E2F axis is a key regulator of the molecular signatures instructing the quiescent and activated adult neural stem cell state. Cell Reports. 41: 111578. PMID 36323247 DOI: 10.1016/j.celrep.2022.111578 |
0.318 |
|
| 2022 |
Corchado-Sonera M, Rambani K, Navarro K, Kladney R, Dowdle J, Leone G, Chamberlin HM. Discovery of non-autonomous modulators of activated Ras. G3 (Bethesda, Md.). PMID 35929788 DOI: 10.1093/g3journal/jkac200 |
0.319 |
|
| 2022 |
Lefler JE, MarElia-Bennett CB, Thies KA, Hildreth BE, Sharma SM, Pitarresi JR, Han L, Everett C, Koivisto C, Cuitino MC, Timmers CD, O'Quinn E, Parrish M, Romeo MJ, Linke AJ, ... ... Leone G, et al. STAT3 in tumor fibroblasts promotes an immunosuppressive microenvironment in pancreatic cancer. Life Science Alliance. 5. PMID 35803738 DOI: 10.26508/lsa.202201460 |
0.307 |
|
| 2022 |
Wu J, Liu X, Wallace Reeser JA, Trimboli AJ, Pecot T, Sizemore GM, Naidu SK, Fernandez SA, Yu L, Hallett M, Park M, Leone GW, Hildreth BE, Ostrowski MC. Stromal p53 Regulates Breast Cancer Development, the Immune Landscape, and Survival in an Oncogene-Specific Manner. Molecular Cancer Research : McR. PMID 35533313 DOI: 10.1158/1541-7786.MCR-21-0960 |
0.342 |
|
| 2022 |
Han L, Seward C, Leone G, Ostrowski MC. Origin, activation and heterogeneity of fibroblasts associated with pancreas and breast cancers. Advances in Cancer Research. 154: 169-201. PMID 35459469 DOI: 10.1016/bs.acr.2022.03.003 |
0.328 |
|
| 2022 |
Yoshida A, Phillips-Mason P, Tarallo V, Avril S, Koivisto C, Leone G, Diehl JA. Non-phosphorylatable cyclin D1 mutant potentiates endometrial hyperplasia and drives carcinoma with Pten loss. Oncogene. PMID 35210557 DOI: 10.1038/s41388-022-02243-8 |
0.328 |
|
| 2020 |
Koivisto CS, Parrish M, Bonala SB, Ngoi S, Torres A, Gallagher J, Sanchez-Hodge R, Zeinner V, Nahhas GJ, Liu B, Cohn DE, Backes FJ, Goodfellow PJ, Chamberlin HM, Leone G. Evaluating the efficacy of enzalutamide and the development of resistance in a preclinical mouse model of type-I endometrial carcinoma. Neoplasia (New York, N.Y.). 22: 484-496. PMID 32818842 DOI: 10.1016/J.Neo.2020.07.003 |
0.409 |
|
| 2020 |
Gao X, Leone GW, Wang H. Cyclin D-CDK4/6 functions in cancer. Advances in Cancer Research. 148: 147-169. PMID 32723562 DOI: 10.1016/Bs.Acr.2020.02.002 |
0.375 |
|
| 2020 |
Thies KA, Hammer AM, Hildreth BE, Steck SA, Spehar JM, Kladney RD, Geisler JM, Das M, Russell LO, Bey JF, Bolyard CM, Pilarski R, Trimboli AJ, Cuitiño MC, Koivisto CS, ... ... Leone G, et al. Stromal platelet-derived growth factor receptor-β signaling promotes breast cancer metastasis in the brain. Cancer Research. PMID 32327406 DOI: 10.1158/0008-5472.Can-19-3731 |
0.426 |
|
| 2020 |
Zhang A, Shinde N, Koivisto CS, Basree MM, Mawalkar RS, Kim HK, Leone G, Majumder S, Ramaswamy B. Abstract P5-07-11: Mammary gland specific Stat3 deletion during involution results in distinct histological changes and higher collagen deposition Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P5-07-11 |
0.425 |
|
| 2020 |
Koivisto CS, Melodie P, Santosh B, Ngoi S, Nahhas GJ, Liu B, Torres A, Gallagher J, Snchez-Hodge R, Zeinner V, Cohn D, Backes F, Goodfellow P, Chamberlin H, Leone G. Abstract 627: Evaluating the efficacy of enzalutamide and the development of resistance in a preclinical mouse model of type-I endometrial carcinoma Cancer Research. 80: 627-627. DOI: 10.1158/1538-7445.Am2020-627 |
0.414 |
|
| 2019 |
Thies KA, Lefler JE, Leone G, Ostrowski MC. PTEN in the Stroma. Cold Spring Harbor Perspectives in Medicine. PMID 31427286 DOI: 10.1101/Cshperspect.A036111 |
0.468 |
|
| 2019 |
Talbert EE, Cuitiño MC, Ladner KJ, Rajasekerea PV, Siebert M, Shakya R, Leone GW, Ostrowski MC, Paleo B, Weisleder N, Reiser PJ, Webb A, Timmers CD, Eiferman DS, Evans DC, et al. Modeling Human Cancer-induced Cachexia. Cell Reports. 28: 1612-1622.e4. PMID 31390573 DOI: 10.1016/J.Celrep.2019.07.016 |
0.336 |
|
| 2019 |
Bowen C, Ostrowski MC, Leone G, Gelmann EP. Loss of PTEN Accelerates NKX3.1 Degradation to Promote Prostate Cancer Progression. Cancer Research. PMID 31213464 DOI: 10.1158/0008-5472.Can-18-4110 |
0.386 |
|
| 2019 |
Cuitiño MC, Pécot T, Sun D, Kladney R, Okano-Uchida T, Shinde N, Saeed R, Perez-Castro AJ, Webb A, Liu T, Bae SI, Clijsters L, Selner N, Coppola V, Timmers C, ... ... Leone G, et al. Two Distinct E2F Transcriptional Modules Drive Cell Cycles and Differentiation. Cell Reports. PMID 31130414 DOI: 10.1016/J.Celrep.2019.05.004 |
0.463 |
|
| 2019 |
Clijsters L, Hoencamp C, Calis JJA, Marzio A, Handgraaf SM, Cuitino MC, Rosenberg BR, Leone G, Pagano M. Cyclin F Controls Cell-Cycle Transcriptional Outputs by Directing the Degradation of the Three Activator E2Fs. Molecular Cell. PMID 31130363 DOI: 10.1016/J.Molcel.2019.04.010 |
0.395 |
|
| 2019 |
Kent LN, Leone G. The broken cycle: E2F dysfunction in cancer. Nature Reviews. Cancer. PMID 31053804 DOI: 10.1038/S41568-019-0143-7 |
0.464 |
|
| 2019 |
Ghatak S, Misra S, Moreno-Rodrigue RA, Hascall VC, Leone GW, Markwald RR. Periostin/β1integrin interaction regulates p21-activated kinases in valvular interstitial cell survival and in actin cytoskeleton reorganization *¶. Biochimica Et Biophysica Acta. General Subjects. PMID 30742951 DOI: 10.1016/J.Bbagen.2018.12.015 |
0.41 |
|
| 2019 |
Thies K, Hammer A, Hildreth B, Russell L, Sizemore S, Trimboli A, Kladney R, Steck S, Das M, Bolyard C, Pilarski R, Cuitino M, Koivisto C, Schoenfield L, Otero J, ... ... Leone G, et al. BSCI-11. STROMAL PLATELET DERIVED GROWTH FACTOR RECEPTOR-β (PDGFRβ) PROMOTES BREAST CANCER BRAIN METASTASIS Neuro-Oncology Advances. 1: i3-i3. DOI: 10.1093/noajnl/vdz014.009 |
0.301 |
|
| 2019 |
Raman S, Singh S, Pécot T, Caserta E, Huang K, Rittscher J, Leone G, Machiraju R. Capturing variations in nuclear phenotypes Journal of Computational Science. 36: 101014. DOI: 10.1016/J.Jocs.2019.07.001 |
0.385 |
|
| 2018 |
Pitarresi JR, Liu X, Avendano A, Thies KA, Sizemore GM, Hammer AM, Hildreth BE, Wang DJ, Steck SA, Donohue S, Cuitiño MC, Kladney RD, Mace TA, Chang JJ, Ennis CS, ... ... Leone G, et al. Disruption of stromal hedgehog signaling initiates RNF5-mediated proteasomal degradation of PTEN and accelerates pancreatic tumor growth. Life Science Alliance. 1: e201800190. PMID 30456390 DOI: 10.26508/lsa.201800190 |
0.328 |
|
| 2018 |
Hsu AH, Lum MA, Shim KS, Frederick PJ, Morrison CD, Chen B, Lele SM, Sheinin YM, Daikoku T, Dey SK, Leone G, Black AR, Black JD. Crosstalk between PKCα and PI3K/AKT Signaling Is Tumor Suppressive in the Endometrium. Cell Reports. 24: 655-669. PMID 30021163 DOI: 10.1016/J.Celrep.2018.06.067 |
0.419 |
|
| 2018 |
Sizemore GM, Balakrishnan S, Thies KA, Hammer AM, Sizemore ST, Trimboli AJ, Cuitiño MC, Steck SA, Tozbikian G, Kladney RD, Shinde N, Das M, Park D, Majumder S, Krishnan S, ... ... Leone G, et al. Stromal PTEN determines mammary epithelial response to radiotherapy. Nature Communications. 9: 2783. PMID 30018330 DOI: 10.1038/S41467-018-05266-6 |
0.371 |
|
| 2018 |
Okano-Uchida T, Kent LN, Ouseph MM, McCarty B, Frank JJ, Kladney R, Cuitino MC, Thompson JC, Coppola V, Asano M, Leone G. Endoreduplication of the mouse genome in the absence of ORC1. Genes & Development. 32: 978-990. PMID 29967292 DOI: 10.1101/Gad.311910.118 |
0.696 |
|
| 2018 |
Ahirwar DK, Nasser MW, Ouseph MM, Elbaz M, Cuitiño MC, Kladney RD, Varikuti S, Kaul K, Satoskar AR, Ramaswamy B, Zhang X, Ostrowski MC, Leone G, Ganju RK. Fibroblast-derived CXCL12 promotes breast cancer metastasis by facilitating tumor cell intravasation. Oncogene. PMID 29720724 DOI: 10.1038/S41388-018-0263-7 |
0.729 |
|
| 2018 |
Rudolph M, Sizemore ST, Lu Y, Teng KY, Basree MM, Reinbolt R, Timmers CD, Leone G, Ostrowski MC, Majumder S, Ramaswamy B. A hedgehog pathway-dependent gene signature is associated with poor clinical outcomes in Luminal A breast cancer. Breast Cancer Research and Treatment. PMID 29464534 DOI: 10.1007/S10549-018-4718-X |
0.333 |
|
| 2018 |
Pellicano F, Park L, Hopcroft LEM, Shah MM, Jackson L, Scott MT, Clarke CJ, Sinclair A, Abraham SA, Hair A, Helgason GV, Aspinall-O'Dea M, Bhatia R, Leone G, Kranc KR, et al. Hsa-mir183/EGR1-mediated regulation of E2F1 is required for CML stem/progenitor cell survival. Blood. PMID 29437554 DOI: 10.1182/Blood-2017-05-783845 |
0.368 |
|
| 2018 |
Talbert EE, Ladner KJ, Cuitino MC, Leone GW, Guttridge DC. Abstract 4090: Generation of a new mouse to model pancreatic cancer-induced cachexia Cancer Research. 78: 4090-4090. DOI: 10.1158/1538-7445.Am2018-4090 |
0.333 |
|
| 2018 |
Basree MM, Shinde N, Koivisto C, Cuitino M, Kladney R, Zhang A, Kim HK, Trimboli A, Zhang J, Leone GW, Sizemore GM, Majumder S, Ramaswamy B. Abstract 2242: Breastfeeding protects against pro-tumorigenic changes in the mammary gland by limiting epithelial luminal progenitor cell expansion Prevention and Research. DOI: 10.1158/1538-7445.Am2018-2242 |
0.349 |
|
| 2017 |
Ollila S, Domènech-Moreno E, Laajanen K, Wong IP, Tripathi S, Pentinmikko N, Gao Y, Yan Y, Niemelä EH, Wang TC, Viollet B, Leone G, Katajisto P, Vaahtomeri K, Mäkelä TP. Stromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathway. The Journal of Clinical Investigation. PMID 29202476 DOI: 10.1172/Jci93597 |
0.433 |
|
| 2017 |
Wu J, Liu X, Nayak SG, Pitarresi JR, Cuitiño MC, Yu L, Hildreth BE, Thies KA, Schilling DJ, Fernandez SA, Leone G, Ostrowski MC. Generation of a pancreatic cancer model using a Pdx1-Flp recombinase knock-in allele. Plos One. 12: e0184984. PMID 28934293 DOI: 10.1371/Journal.Pone.0184984 |
0.451 |
|
| 2017 |
Ratnam NM, Peterson JM, Talbert EE, Ladner KJ, Rajasekera PV, Schmidt CR, Dillhoff ME, Swanson BJ, Haverick E, Kladney RD, Williams TM, Leone GW, Wang DJ, Guttridge DC. NF-κB regulates GDF-15 to suppress macrophage surveillance during early tumor development. The Journal of Clinical Investigation. PMID 28891811 DOI: 10.1172/Jci91561 |
0.389 |
|
| 2017 |
Liu H, Dowdle JA, Khurshid S, Sullivan NJ, Bertos N, Rambani K, Mair M, Daniel P, Wheeler E, Tang X, Toth K, Lause M, Harrigan ME, Eiring K, Sullivan C, ... ... Leone G, et al. Discovery of Stromal Regulatory Networks that Suppress Ras-Sensitized Epithelial Cell Proliferation. Developmental Cell. 41: 392-407.e6. PMID 28535374 DOI: 10.1016/J.Devcel.2017.04.024 |
0.454 |
|
| 2017 |
Hammer AM, Sizemore GM, Shukla VC, Avendano A, Sizemore ST, Chang JJ, Kladney RD, Cuitiño MC, Thies KA, Verfurth Q, Chakravarti A, Yee LD, Leone G, Song JW, Ghadiali SN, et al. Stromal PDGFR-α Activation Enhances Matrix Stiffness, Impedes Mammary Ductal Development, and Accelerates Tumor Growth. Neoplasia (New York, N.Y.). 19: 496-508. PMID 28501760 DOI: 10.1016/J.Neo.2017.04.004 |
0.401 |
|
| 2017 |
Kent LN, Bae S, Tsai SY, Tang X, Srivastava A, Koivisto C, Martin CK, Ridolfi E, Miller GC, Zorko SM, Plevris E, Hadjiyannis Y, Perez M, Nolan E, Kladney R, ... ... Leone G, et al. Dosage-dependent copy number gains in E2f1 and E2f3 drive hepatocellular carcinoma. The Journal of Clinical Investigation. PMID 28134624 DOI: 10.1172/Jci87583 |
0.405 |
|
| 2016 |
Sizemore GM, Balakrishnan S, Hammer AM, Thies KA, Trimboli AJ, Wallace JA, Sizemore ST, Kladney RD, Woelke SA, Yu L, Fernandez SA, Chakravarti A, Leone G, Ostrowski MC. Stromal PTEN inhibits the expansion of mammary epithelial stem cells through Jagged-1. Oncogene. PMID 27797378 DOI: 10.1038/Onc.2016.383 |
0.482 |
|
| 2016 |
Pitarresi JR, Liu X, Sharma SM, Cuitiño MC, Kladney RD, Mace TA, Donohue S, Nayak SG, Qu C, Lee J, Woelke SA, Trela S, LaPak K, Yu L, McElroy J, ... ... Leone G, et al. Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia. Neoplasia (New York, N.Y.). 18: 541-52. PMID 27659014 DOI: 10.1016/J.Neo.2016.07.006 |
0.441 |
|
| 2016 |
Liu X, Pitarresi JR, Cuitiño MC, Kladney RD, Woelke SA, Sizemore GM, Nayak SG, Egriboz O, Schweickert PG, Yu L, Trela S, Schilling DJ, Halloran SK, Li M, Dutta S, ... ... Leone G, et al. Genetic ablation of Smoothened in pancreatic fibroblasts increases acinar-ductal metaplasia. Genes & Development. PMID 27633013 DOI: 10.1101/Gad.283499.116 |
0.43 |
|
| 2016 |
Jones RA, Robinson TJ, Liu JC, Shrestha M, Voisin V, Ju Y, Chung PE, Pellecchia G, Fell VL, Bae S, Muthuswamy L, Datti A, Egan SE, Jiang Z, Leone G, et al. RB1 deficiency in triple-negative breast cancer induces mitochondrial protein translation. The Journal of Clinical Investigation. PMID 27571409 DOI: 10.1172/Jci81568 |
0.474 |
|
| 2016 |
Kent LN, Rakijas JB, Pandit SK, Westendorp B, Chen HZ, Huntington JT, Tang X, Bae S, Srivastava A, Senapati S, Koivisto C, Martin CK, Cuitino MC, Perez M, Clouse JM, ... ... Leone G, et al. E2f8 mediates tumor suppression in postnatal liver development. The Journal of Clinical Investigation. PMID 27454291 DOI: 10.1172/Jci85506 |
0.627 |
|
| 2016 |
Thurlings I, Martínez-López LM, Westendorp B, Zijp M, Kuiper R, Tooten P, Kent LN, Leone G, Vos HJ, Burgering B, de Bruin A. Synergistic functions of E2F7 and E2F8 are critical to suppress stress-induced skin cancer. Oncogene. PMID 27452520 DOI: 10.1038/Onc.2016.251 |
0.433 |
|
| 2016 |
Tang X, Liu H, Srivastava A, Pécot T, Chen Z, Wang Q, Huang K, Sáenz-Robles MT, Cantalupo P, Pipas J, Leone G. Transcriptome regulation and chromatin occupancy by E2F3 and MYC in mice. Scientific Data. 3: 160008. PMID 26881867 DOI: 10.1038/Sdata.2016.8 |
0.376 |
|
| 2016 |
Chaffee BR, Hoang TV, Leonard MR, Bruney DG, Wagner BD, Dowd JR, Leone G, Ostrowski MC, Robinson ML. FGFR and PTEN signaling interact during lens development to regulate cell survival. Developmental Biology. PMID 26764128 DOI: 10.1016/J.Ydbio.2015.12.027 |
0.424 |
|
| 2016 |
Leone GW. Abstract IA16: Breaking the balance between E2F activators and atypical repressors: Consequences to development and cancer Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Cellcycle16-Ia16 |
0.472 |
|
| 2016 |
Sizemore G, Mathur A, Thies K, Bolyard C, Sizemore S, Kladney R, Trimboli A, Kaur B, Leone G, Ostrowski M. Abstract C28: Platelet-derived growth factor receptor-β (PDGFRβ) in the breast metastatic tumor microenvironment Cancer Research. 76. DOI: 10.1158/1538-7445.Tme16-C28 |
0.422 |
|
| 2016 |
Rambani K, Kladney R, Chang S, Harrigan M, Dowdle J, Tang X, Liu H, Brunner E, Chamberlin H, Leone G. Abstract 919: A genome-wide screen in C. elegans identifies cell non-autonomous suppressors of let-60/RAS mediated oncogenic over-proliferation Cancer Research. 76: 919-919. DOI: 10.1158/1538-7445.Am2016-919 |
0.479 |
|
| 2016 |
Hsu AH, Curry KJ, Shim K, Frederick P, Morrison CD, Chen B, Lele SM, Daikoku T, Dey SK, Leone G, Black AR, Black JD. Abstract 189: Protein kinase C alpha suppresses AKT activation in endometrial cancer Cancer Research. 76: 189-189. DOI: 10.1158/1538-7445.Am2016-189 |
0.459 |
|
| 2015 |
Huntington JT, Tang X, Kent LN, Schmidt CR, Leone G. The Spectrum of E2F in Liver Disease - Mediated Regulation in Biology and Cancer. Journal of Cellular Physiology. PMID 26566968 DOI: 10.1002/Jcp.25242 |
0.403 |
|
| 2015 |
Trikha P, Sharma N, Pena C, Reyes A, Pécot T, Khurshid S, Rawahneh M, Moffitt J, Stephens JA, Fernandez SA, Ostrowski MC, Leone G. E2f3 in tumor macrophages promotes lung metastasis. Oncogene. PMID 26549026 DOI: 10.1038/Onc.2015.429 |
0.492 |
|
| 2015 |
Clements AE, Bravo V, Koivisto C, Cohn DE, Leone G. WWP2 and its association with PTEN in endometrial cancer. Gynecologic Oncology Reports. 13: 26-9. PMID 26425715 DOI: 10.1016/J.Gore.2015.05.004 |
0.381 |
|
| 2015 |
Caserta E, Egriboz O, Wang H, Martin C, Koivisto C, Pecót T, Kladney RD, Shen C, Shim KS, Pham T, Karikomi MK, Mauntel MJ, Majumder S, Cuitino MC, Tang X, ... ... Leone G, et al. Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo. Genes & Development. 29: 1707-20. PMID 26302789 DOI: 10.1101/Gad.262568.115 |
0.388 |
|
| 2015 |
Liu H, Tang X, Srivastava A, Pécot T, Daniel P, Hemmelgarn B, Reyes S, Fackler N, Bajwa A, Kladney R, Koivisto C, Chen Z, Wang Q, Huang K, Machiraju R, ... ... Leone G, et al. Redeployment of Myc and E2f1-3 drives Rb-deficient cell cycles. Nature Cell Biology. PMID 26192440 DOI: 10.1038/Ncb3210 |
0.413 |
|
| 2015 |
Julian LM, Liu Y, Pakenham CA, Dugal-Tessier D, Ruzhynsky V, Bae S, Tsai SY, Leone G, Slack RS, Blais A. Tissue-specific targeting of cell fate regulatory genes by E2f factors. Cell Death and Differentiation. PMID 25909886 DOI: 10.1038/Cdd.2015.36 |
0.462 |
|
| 2015 |
Briercheck EL, Trotta R, Chen L, Hartlage AS, Cole JP, Cole TD, Mao C, Banerjee PP, Hsu HT, Mace EM, Ciarlariello D, Mundy-Bosse BL, Garcia-Cao I, Scoville SD, Yu L, ... ... Leone G, et al. PTEN is a negative regulator of NK cell cytolytic function. Journal of Immunology (Baltimore, Md. : 1950). 194: 1832-40. PMID 25595786 DOI: 10.4049/Jimmunol.1401224 |
0.37 |
|
| 2015 |
Wu L, de Bruin A, Wang H, Simmons T, Cleghorn W, Goldenberg LE, Sites E, Sandy A, Trimboli A, Fernandez SA, Eng C, Shapiro C, Leone G. Selective roles of E2Fs for ErbB2- and Myc-mediated mammary tumorigenesis Oncogene. 34: 119-128. PMID 24276244 DOI: 10.1038/Onc.2013.511 |
0.466 |
|
| 2015 |
Reinbolt RE, Tolliver K, Abdel-Rasoul M, Timmers C, Ramaswamy B, Layman RM, Wesolowski R, Lustberg MB, Mrozek E, Ottman S, Chen J, Shapiro C, Ostrowski MC, Leone GW, Macrae E. Abstract P2-03-03: Incidence of actionable genomic alterations in metastatic breast cancer: A prospective study Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P2-03-03 |
0.333 |
|
| 2015 |
Mathur A, Sizemore GM, Balakrishnan S, Shukla VC, Cuitino M, Trimboli AJ, Ghadiali S, Leone GW, Ostrowski MC. Abstract 985: Stromal PDGFR-α activation stalls mammary ductal development and increases tumorigenic potential of mammary epithelia Cancer Research. 75: 985-985. DOI: 10.1158/1538-7445.Am2015-985 |
0.439 |
|
| 2015 |
Hsu AH, Curry KJ, Shim K, Frederick P, Morrison C, Chen B, Lele SM, Daikoku T, Dey SK, Leone G, Black AR, Black JD. Abstract 4720: Protein kinase C alpha (PKCα) regulates PI3K/AKT signaling in endometrial cancer Cancer Research. 75: 4720-4720. DOI: 10.1158/1538-7445.Am2015-4720 |
0.417 |
|
| 2014 |
Sáenz Robles MT, Chong JL, Koivisto C, Trimboli A, Liu H, Leone G, Pipas JM. Viral oncogene expression in the stem/progenitor cell compartment of the mouse intestine induces adenomatous polyps. Molecular Cancer Research : McR. 12: 1355-64. PMID 24994749 DOI: 10.1158/1541-7786.Mcr-14-0166 |
0.394 |
|
| 2014 |
Moreau JLM, Artap ST, Shi H, Chapman G, Leone G, Sparrow DB, Dunwoodie SL. Cited2 is required in trophoblasts for correct placental capillary patterning Developmental Biology. 392: 62-79. PMID 24803182 DOI: 10.1016/J.Ydbio.2014.04.023 |
0.409 |
|
| 2014 |
Cecchini MJ, Thwaites MJ, Talluri S, MacDonald JI, Passos DT, Chong JL, Cantalupo P, Stafford PM, Sáenz-Robles MT, Francis SM, Pipas JM, Leone G, Welch I, Dick FA. A retinoblastoma allele that is mutated at its common E2F interaction site inhibits cell proliferation in gene-targeted mice. Molecular and Cellular Biology. 34: 2029-45. PMID 24662053 DOI: 10.1128/Mcb.01589-13 |
0.5 |
|
| 2014 |
Rath KS, Naidu SK, Lata P, Bid HK, Rivera BK, McCann GA, Tierney BJ, Elnaggar AC, Bravo V, Leone G, Houghton P, Hideg K, Kuppusamy P, Cohn DE, Selvendiran K. HO-3867, a safe STAT3 inhibitor, is selectively cytotoxic to ovarian cancer. Cancer Research. 74: 2316-27. PMID 24590057 DOI: 10.1158/0008-5472.Can-13-2433 |
0.436 |
|
| 2014 |
Schmidt JW, Wehde BL, Sakamoto K, Triplett AA, Anderson SM, Tsichlis PN, Leone G, Wagner KU. Stat5 regulates the phosphatidylinositol 3-kinase/Akt1 pathway during mammary gland development and tumorigenesis. Molecular and Cellular Biology. 34: 1363-77. PMID 24469394 DOI: 10.1128/Mcb.01220-13 |
0.477 |
|
| 2014 |
Hsu AH, Curry KJ, Shim K, Frederick P, Morrison CD, Chen B, Lele SM, Leone G, Black AR, Black JD. Abstract 4211: Protein kinase C alpha (PKCα) signaling in endometrial cancer Cancer Research. 74: 4211-4211. DOI: 10.1158/1538-7445.Am2014-4211 |
0.447 |
|
| 2014 |
Mathsyaraja H, Thies K, Taffany DA, Deighan C, Liu T, Yu L, Fernandez SA, Shapiro C, Otero J, Timmers C, Lustberg MB, Chalmers J, Leone G, Ostrowski MC. CSF1-ETS2-induced microRNA in myeloid cells promote metastatic tumor growth Oncogene. DOI: 10.1038/Onc.2014.294 |
0.305 |
|
| 2013 |
Wallace JA, Li F, Balakrishnan S, Cantemir-Stone CZ, Pecot T, Martin C, Kladney RD, Sharma SM, Trimboli AJ, Fernandez SA, Yu L, Rosol TJ, Stromberg PC, Lesurf R, Hallett M, ... ... Leone G, et al. Ets2 in tumor fibroblasts promotes angiogenesis in breast cancer. Plos One. 8: e71533. PMID 23977064 DOI: 10.1371/Journal.Pone.0071533 |
0.454 |
|
| 2013 |
Lu J, Zhang S, Nakano H, Simmons DG, Wang S, Kong S, Wang Q, Shen L, Tu Z, Wang W, Wang B, Wang H, Wang Y, van Es JH, Clevers H, ... Leone G, et al. A positive feedback loop involving Gcm1 and Fzd5 directs chorionic branching morphogenesis in the placenta. Plos Biology. 11: e1001536. PMID 23610556 DOI: 10.1371/Journal.Pbio.1001536 |
0.376 |
|
| 2013 |
Julian LM, Vandenbosch R, Pakenham CA, Andrusiak MG, Nguyen AP, McClellan KA, Svoboda DS, Lagace DC, Park DS, Leone G, Blais A, Slack RS. Opposing regulation of Sox2 by cell-cycle effectors E2f3a and E2f3b in neural stem cells. Cell Stem Cell. 12: 440-52. PMID 23499385 DOI: 10.1016/J.Stem.2013.02.001 |
0.425 |
|
| 2013 |
Wallace JA, Li F, Balakrishnan S, Cantemir-Stone CZ, Pecot T, Martin C, Kladney RD, Sharma SM, Trimboli AJ, Fernandez SA, Yu L, Rosol TJ, Stromberg PC, Lesurf R, Hallett M, ... ... Leone G, et al. Ets2 in fibroblasts controls tumor angiogenesis. Plos One. DOI: 10.1371/Journal.Pone.0071533.G004 |
0.333 |
|
| 2013 |
Laajanen K, Ollila S, Wong IP, Vaahtomeri K, Leone G, Viollet B, Tomi MP. Abstract C55: Investigating mechanisms of gastrointestinal polyposis and osteoblastic tumor formation induced by mesenchymal Lkb1 deficiency Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-C55 |
0.436 |
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| 2013 |
Clements A, McElroy J, Suarez A, Majumder S, Cohn D, Leone G. Abstract 1992: Is the ubiquitin ligase WWP2 playing a role in PTEN degradation in endometrial cancer. Cancer Research. 73: 1992-1992. DOI: 10.1158/1538-7445.Am2013-1992 |
0.394 |
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| 2013 |
Balakrishnan S, Wallace JA, Li F, Martin CK, Pecot T, Leone G, Ostrowski MC. Abstract 1633: Ets2 in tumor fibroblasts promotes angiogenesis in breast cancer. Cancer Research. 73: 1633-1633. DOI: 10.1158/1538-7445.Am2013-1633 |
0.459 |
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| 2013 |
Selvendiran K, Rath KS, Naidu S, Latha P, Hemant B, McCann GA, Bravo V, Houghton P, Leone G, Hideg K, Kuppusamy P, Cohn DE. Abstract A253: HO-3867, a safe STAT3 inhibitor, is selectively cytotoxic to ovarian cancer. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-A253 |
0.396 |
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| 2012 |
Chen HZ, Ouseph MM, Li J, Pécot T, Chokshi V, Kent L, Bae S, Byrne M, Duran C, Comstock G, Trikha P, Mair M, Senapati S, Martin CK, Gandhi S, ... ... Leone G, et al. Canonical and atypical E2Fs regulate the mammalian endocycle. Nature Cell Biology. 14: 1192-202. PMID 23064266 DOI: 10.1038/Ncb2595 |
0.781 |
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| 2012 |
Weijts BG, Bakker WJ, Cornelissen PW, Liang KH, Schaftenaar FH, Westendorp B, de Wolf CA, Paciejewska M, Scheele CL, Kent L, Leone G, Schulte-Merker S, de Bruin A. E2F7 and E2F8 promote angiogenesis through transcriptional activation of VEGFA in cooperation with HIF1. The Embo Journal. 31: 3871-84. PMID 22903062 DOI: 10.1038/Emboj.2012.231 |
0.407 |
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| 2012 |
Kim JW, Evans C, Weidemann A, Takeda N, Lee YS, Stockmann C, Branco-Price C, Brandberg F, Leone G, Ostrowski MC, Johnson RS. Loss of fibroblast HIF-1α accelerates tumorigenesis. Cancer Research. 72: 3187-95. PMID 22556263 DOI: 10.1158/0008-5472.Can-12-0534 |
0.384 |
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| 2012 |
Ouseph MM, Li J, Chen HZ, Pécot T, Wenzel P, Thompson JC, Comstock G, Chokshi V, Byrne M, Forde B, Chong JL, Huang K, Machiraju R, de Bruin A, Leone G. Atypical E2F repressors and activators coordinate placental development. Developmental Cell. 22: 849-62. PMID 22516201 DOI: 10.1016/J.Devcel.2012.01.013 |
0.77 |
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| 2012 |
McClory S, Hughes T, Freud AG, Briercheck EL, Martin C, Trimboli AJ, Yu J, Zhang X, Leone G, Nuovo G, Caligiuri MA. Evidence for a stepwise program of extrathymic T cell development within the human tonsil. The Journal of Clinical Investigation. 122: 1403-15. PMID 22378041 DOI: 10.1172/Jci46125 |
0.355 |
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| 2012 |
Bronisz A, Godlewski J, Wallace JA, Merchant AS, Nowicki MO, Mathsyaraja H, Srinivasan R, Trimboli AJ, Martin CK, Li F, Yu L, Fernandez SA, Pécot T, Rosol TJ, Cory S, ... ... Leone G, et al. Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320. Nature Cell Biology. 14: 159-67. PMID 22179046 DOI: 10.1038/Ncb2396 |
0.351 |
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| 2012 |
Nasser MW, Qamri Z, Deol YS, Ravi J, Powell CA, Trikha P, Schwendener RA, Bai XF, Shilo K, Zou X, Leone G, Wolf R, Yuspa SH, Ganju RK. S100A7 enhances mammary tumorigenesis through upregulation of inflammatory pathways. Cancer Research. 72: 604-15. PMID 22158945 DOI: 10.1158/0008-5472.Can-11-0669 |
0.421 |
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| 2012 |
Briercheck EL, Trotta R, Cole JP, Cole TD, Hartlage AS, Martin CK, Leone G, Caligiuri MA. Human Natural Killer (NK) Cells: Differential Expression of Phosphatase and Tensin Homologue Deleted On Chromosome Ten (PTEN) During NK Cell Development Regulates Its Cytolytic Activity Against Leukemic Target Cells Blood. 120: 254-254. DOI: 10.1182/Blood.V120.21.254.254 |
0.399 |
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| 2011 |
Sáenz Robles MT, Case A, Chong JL, Leone G, Pipas JM. The retinoblastoma tumor suppressor regulates a xenobiotic detoxification pathway. Plos One. 6: e26019. PMID 22022495 DOI: 10.1371/Journal.Pone.0026019 |
0.508 |
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| 2011 |
Wallace JA, Li F, Leone G, Ostrowski MC. Pten in the breast tumor microenvironment: modeling tumor-stroma coevolution. Cancer Research. 71: 1203-7. PMID 21303970 DOI: 10.1158/0008-5472.Can-10-3263 |
0.376 |
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| 2011 |
Wenzel PL, Chong JL, Sáenz-Robles MT, Ferrey A, Hagan JP, Gomez YM, Rajmohan R, Sharma N, Chen HZ, Pipas JM, Robinson ML, Leone G. Cell proliferation in the absence of E2F1-3. Developmental Biology. 351: 35-45. PMID 21185283 DOI: 10.1016/J.Ydbio.2010.12.025 |
0.799 |
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| 2011 |
Trikha P, Sharma N, Opavsky R, Reyes A, Pena C, Ostrowski MC, Roussel MF, Leone G. E2f1-3 are critical for myeloid development. The Journal of Biological Chemistry. 286: 4783-95. PMID 21115501 DOI: 10.1074/Jbc.M110.182733 |
0.47 |
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| 2011 |
Bronisz AM, Godlewski J, Wallace J, Merchant A, Leone G, Ostrowski MC. Abstract 512: Reprogramming of the tumor microenvironment by stromalPten-regulated miR-320 Cancer Research. 71: 512-512. DOI: 10.1158/1538-7445.Am2011-512 |
0.387 |
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| 2011 |
Nasser MW, Qamri Z, Deol YS, Leone G, Zou X, Wolf R, Yuspa SH, Ganju RK. Abstract 403: Overexpression of S100A7 enhances mammary tumorigenesis through upregulation of inflammatory pathways Cancer Research. 71: 403-403. DOI: 10.1158/1538-7445.Am2011-403 |
0.428 |
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| 2011 |
Schmidt J, Sakamoto K, Creamer B, Leone G, Wagner K. P4-03-01: Stat5 Regulates the PI3-Kinase/Akt1 Pathway during Mammary Gland Development and Promotes Neoplastic Transformation in a Mouse Model for Cowden Syndrome. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-P4-03-01 |
0.471 |
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| 2010 |
Zeng X, Shaikh FY, Harrison MK, Adon AM, Trimboli AJ, Carroll KA, Sharma N, Timmers C, Chodosh LA, Leone G, Saavedra HI. The Ras oncogene signals centrosome amplification in mammary epithelial cells through cyclin D1/Cdk4 and Nek2 Oncogene. 29: 5103-5112. PMID 20581865 DOI: 10.1038/Onc.2010.253 |
0.315 |
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| 2010 |
Wang H, Karikomi M, Naidu S, Rajmohan R, Caserta E, Chen HZ, Rawahneh M, Moffitt J, Stephens JA, Fernandez SA, Weinstein M, Wang D, Sadee W, La Perle K, Stromberg P, ... ... Leone G, et al. Allele-specific tumor spectrum in pten knockin mice. Proceedings of the National Academy of Sciences of the United States of America. 107: 5142-7. PMID 20194734 DOI: 10.1073/Pnas.0912524107 |
0.769 |
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| 2010 |
Zabuawala T, Taffany DA, Sharma SM, Merchant A, Adair B, Srinivasan R, Rosol TJ, Fernandez S, Huang K, Leone G, Ostrowski MC. An ets2-driven transcriptional program in tumor-associated macrophages promotes tumor metastasis. Cancer Research. 70: 1323-33. PMID 20145133 DOI: 10.1158/0008-5472.Can-09-1474 |
0.432 |
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| 2010 |
Martinez LA, Goluszko E, Chen HZ, Leone G, Post S, Lozano G, Chen Z, Chauchereau A. E2F3 is a mediator of DNA damage-induced apoptosis. Molecular and Cellular Biology. 30: 524-36. PMID 19917728 DOI: 10.1128/Mcb.00938-09 |
0.568 |
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| 2010 |
Nasser MW, Qamri Z, Adel M, Abdussamad A, Leone G, Yuspa SH, Ganju RK. Abstract 3949: S100A7 modulates growth factor-mediated signaling in estrogen receptor negative breast cancer Cancer Research. 70: 3949-3949. DOI: 10.1158/1538-7445.Am10-3949 |
0.447 |
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| 2010 |
Wang H, Karikomi M, Naidu S, Rajmohan R, Caserta E, Chen H, Rawahneh M, Moffitt J, Stephens JA, Fernandez SA, Weinstein M, Perle KL, Stromberg P, Rosol TJ, Eng C, ... ... Leone G, et al. Abstract 3260: Allele-specific tumor spectrum inPtenknockin mice Cancer Research. 70: 3260-3260. DOI: 10.1158/1538-7445.Am10-3260 |
0.771 |
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| 2010 |
Trikha P, Pena C, Sharma N, Reyes A, Leone G. Abstract 1349: Ablation ofE2f3in macrophages reduces the incidence of lung metastasis Cancer Research. 70: 1349-1349. DOI: 10.1158/1538-7445.Am10-1349 |
0.442 |
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| 2010 |
Jia H, Ilieva L, Wu X, Leone G, Pohar K. 791 E2F3A AND E2F3B ARE EXPRESSED IN BLADDER CANCER AND PROMOTE TUMOR GROWTH Journal of Urology. 183. DOI: 10.1016/J.Juro.2010.02.1440 |
0.367 |
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| 2009 |
Chong JL, Wenzel PL, Sáenz-Robles MT, Nair V, Ferrey A, Hagan JP, Gomez YM, Sharma N, Chen HZ, Ouseph M, Wang SH, Trikha P, Culp B, Mezache L, Winton DJ, ... ... Leone G, et al. E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells. Nature. 462: 930-4. PMID 20016602 DOI: 10.1038/Nature08677 |
0.785 |
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| 2009 |
Chen D, Pacal M, Wenzel P, Knoepfler PS, Leone G, Bremner R. Division and apoptosis of E2f-deficient retinal progenitors. Nature. 462: 925-9. PMID 20016601 DOI: 10.1038/Nature08544 |
0.484 |
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| 2009 |
Srinivasan R, Zabuawala T, Huang H, Zhang J, Gulati P, Fernandez S, Karlo JC, Landreth GE, Leone G, Ostrowski MC. Erk1 and Erk2 regulate endothelial cell proliferation and migration during mouse embryonic angiogenesis. Plos One. 4: e8283. PMID 20011539 DOI: 10.1371/Journal.Pone.0008283 |
0.392 |
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| 2009 |
Qamri Z, Preet A, Nasser MW, Bass CE, Leone G, Barsky SH, Ganju RK. Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer. Molecular Cancer Therapeutics. 8: 3117-29. PMID 19887554 DOI: 10.1158/1535-7163.Mct-09-0448 |
0.377 |
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| 2009 |
Chen HZ, Tsai SY, Leone G. Emerging roles of E2Fs in cancer: an exit from cell cycle control. Nature Reviews. Cancer. 9: 785-97. PMID 19851314 DOI: 10.1038/Nrc2696 |
0.66 |
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| 2009 |
Trimboli AJ, Cantemir-Stone CZ, Li F, Wallace JA, Merchant A, Creasap N, Thompson JC, Caserta E, Wang H, Chong JL, Naidu S, Wei G, Sharma SM, Stephens JA, Fernandez SA, ... ... Leone G, et al. Pten in stromal fibroblasts suppresses mammary epithelial tumours. Nature. 461: 1084-91. PMID 19847259 DOI: 10.1038/Nature08486 |
0.389 |
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| 2009 |
Eng C, Leone G, Orloff MS, Ostrowski MC. Genomic alterations in tumor stroma. Cancer Research. 69: 6759-64. PMID 19706759 DOI: 10.1158/0008-5472.Can-09-0985 |
0.323 |
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| 2009 |
Wei G, Srinivasan R, Cantemir-Stone CZ, Sharma SM, Santhanam R, Weinstein M, Muthusamy N, Man AK, Oshima RG, Leone G, Ostrowski MC. Ets1 and Ets2 are required for endothelial cell survival during embryonic angiogenesis. Blood. 114: 1123-30. PMID 19411629 DOI: 10.1182/Blood-2009-03-211391 |
0.393 |
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| 2009 |
Lammens T, Li J, Leone G, De Veylder L. Atypical E2Fs: new players in the E2F transcription factor family. Trends in Cell Biology. 19: 111-8. PMID 19201609 DOI: 10.1016/J.Tcb.2009.01.002 |
0.421 |
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| 2009 |
Chong JL, Tsai SY, Sharma N, Opavsky R, Price R, Wu L, Fernandez SA, Leone G. E2f3a and E2f3b contribute to the control of cell proliferation and mouse development. Molecular and Cellular Biology. 29: 414-24. PMID 19015245 DOI: 10.1128/Mcb.01161-08 |
0.483 |
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| 2008 |
Tsai SY, Opavsky R, Sharma N, Wu L, Naidu S, Nolan E, Feria-Arias E, Timmers C, Opavska J, de Bruin A, Chong JL, Trikha P, Fernandez SA, Stromberg P, Rosol TJ, ... Leone G, et al. Mouse development with a single E2F activator. Nature. 454: 1137-41. PMID 18594513 DOI: 10.1038/Nature07066 |
0.405 |
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| 2008 |
Nadella KS, Jones GN, Trimboli A, Stratakis CA, Leone G, Kirschner LS. Targeted deletion of Prkar1a reveals a role for protein kinase A in mesenchymal-to-epithelial transition. Cancer Research. 68: 2671-7. PMID 18413734 DOI: 10.1158/0008-5472.Can-07-6002 |
0.454 |
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| 2008 |
Trimboli AJ, Fukino K, de Bruin A, Wei G, Shen L, Tanner SM, Creasap N, Rosol TJ, Robinson ML, Eng C, Ostrowski MC, Leone G. Direct evidence for epithelial-mesenchymal transitions in breast cancer. Cancer Research. 68: 937-45. PMID 18245497 DOI: 10.1158/0008-5472.Can-07-2148 |
0.369 |
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| 2008 |
Li J, Ran C, Li E, Gordon F, Comstock G, Siddiqui H, Cleghorn W, Chen HZ, Kornacker K, Liu CG, Pandit SK, Khanizadeh M, Weinstein M, Leone G, de Bruin A. Synergistic function of E2F7 and E2F8 is essential for cell survival and embryonic development. Developmental Cell. 14: 62-75. PMID 18194653 DOI: 10.1016/J.Devcel.2007.10.017 |
0.646 |
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| 2008 |
Eiring AM, Neviani P, Santhanam R, Oaks JJ, Chang JS, Notari M, Willis W, Gambacorti-Passerini C, Volinia S, Marcucci G, Caligiuri MA, Leone GW, Perrotti D. Identification of novel posttranscriptional targets of the BCR/ABL oncoprotein by ribonomics: requirement of E2F3 for BCR/ABL leukemogenesis. Blood. 111: 816-28. PMID 17925491 DOI: 10.1182/Blood-2007-05-090472 |
0.394 |
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| 2007 |
Opavsky R, Wang SH, Trikha P, Raval A, Huang Y, Wu YZ, Rodriguez B, Keller B, Liyanarachchi S, Wei G, Davuluri RV, Weinstein M, Felsher D, Ostrowski M, Leone G, et al. CpG island methylation in a mouse model of lymphoma is driven by the genetic configuration of tumor cells. Plos Genetics. 3: 1757-69. PMID 17907813 DOI: 10.1371/Journal.Pgen.0030167 |
0.397 |
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| 2007 |
Opavsky R, Tsai SY, Guimond M, Arora A, Opavska J, Becknell B, Kaufmann M, Walton NA, Stephens JA, Fernandez SA, Muthusamy N, Felsher DW, Porcu P, Caligiuri MA, Leone G. Specific tumor suppressor function for E2F2 in Myc-induced T cell lymphomagenesis. Proceedings of the National Academy of Sciences of the United States of America. 104: 15400-5. PMID 17881568 DOI: 10.1073/Pnas.0706307104 |
0.474 |
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| 2007 |
Sáenz-Robles MT, Markovics JA, Chong JL, Opavsky R, Whitehead RH, Leone G, Pipas JM. Intestinal hyperplasia induced by simian virus 40 large tumor antigen requires E2F2 Journal of Virology. 81: 13191-13199. PMID 17855529 DOI: 10.1128/Jvi.01658-07 |
0.377 |
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| 2007 |
Chen D, Opavsky R, Pacal M, Tanimoto N, Wenzel P, Seeliger MW, Leone G, Bremner R. Rb-mediated neuronal differentiation through cell-cycle-independent regulation of E2f3a. Plos Biology. 5: e179. PMID 17608565 DOI: 10.1371/Journal.Pbio.0050179 |
0.447 |
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| 2007 |
McClellan KA, Ruzhynsky VA, Douda DN, Vanderluit JL, Ferguson KL, Chen D, Bremner R, Park DS, Leone G, Slack RS. Unique requirement for Rb/E2F3 in neuronal migration: evidence for cell cycle-independent functions. Molecular and Cellular Biology. 27: 4825-43. PMID 17452454 DOI: 10.1128/Mcb.02100-06 |
0.436 |
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| 2007 |
Wenzel PL, Leone G. Expression of Cre recombinase in early diploid trophoblast cells of the mouse placenta. Genesis. 45: 129-134. PMID 17299749 DOI: 10.1002/Dvg.20276 |
0.427 |
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| 2007 |
Wenzel PL, Wu L, de Bruin A, Chong JL, Chen WY, Dureska G, Sites E, Pan T, Sharma A, Huang K, Ridgway R, Mosaliganti K, Sharp R, Machiraju R, Saltz J, ... ... Leone G, et al. Rb is critical in a mammalian tissue stem cell population. Genes & Development. 21: 85-97. PMID 17210791 DOI: 10.1101/Gad.1485307 |
0.436 |
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| 2007 |
Timmers C, Sharma N, Opavsky R, Maiti B, Wu L, Wu J, Orringer D, Trikha P, Saavedra HI, Leone G. E2f1, E2f2, and E2f3 control E2F target expression and cellular proliferation via a p53-dependent negative feedback loop. Molecular and Cellular Biology. 27: 65-78. PMID 17167174 DOI: 10.1128/MCB.02147-06 |
0.305 |
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| 2007 |
Eiring AM, Neviani P, Santhanam R, Oaks JJ, Chang JS, Gambacorti-Passerini C, Volinia S, Marcucci G, Caligiuri MA, Leone GW, Perrotti D. Requirement of the E2F3 Transcription Factor for BCR/ABL Leukemogenesis. Blood. 110: 33-33. DOI: 10.1182/Blood.V110.11.33.33 |
0.416 |
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| 2007 |
Timmers C, Sharma N, Opavsky R, Maiti B, Wu L, Wu J, Orringer D, Trikha P, Saavedra HI, Leone G. E2f1, E2f2, and E2f3 Control E2F Target Expression and Cellular Proliferation via a p53-Dependent Negative Feedback Loop Molecular and Cellular Biology. 27: 65-78. DOI: 10.1128/Mcb.02147-05 |
0.418 |
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| 2006 |
Sharma N, Timmers C, Trikha P, Saavedra HI, Obery A, Leone G. Control of the p53-p21CIP1 Axis by E2f1, E2f2, and E2f3 is essential for G1/S progression and cellular transformation. The Journal of Biological Chemistry. 281: 36124-31. PMID 17008321 DOI: 10.1074/Jbc.M604152200 |
0.429 |
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| 2006 |
Dorrance AM, Liu S, Yuan W, Becknell B, Arnoczky KJ, Guimond M, Strout MP, Feng L, Nakamura T, Yu L, Rush LJ, Weinstein M, Leone G, Wu L, Ferketich A, et al. Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations. The Journal of Clinical Investigation. 116: 2707-16. PMID 16981007 DOI: 10.1172/Jci25546 |
0.377 |
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| 2005 |
Logan N, Graham A, Zhao X, Fisher R, Maiti B, Leone G, La Thangue NB. E2F-8: an E2F family member with a similar organization of DNA-binding domains to E2F-7. Oncogene. 24: 5000-4. PMID 15897886 DOI: 10.1038/Sj.Onc.1208703 |
0.399 |
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| 2005 |
Maiti B, Li J, de Bruin A, Gordon F, Timmers C, Opavsky R, Patil K, Tuttle J, Cleghorn W, Leone G. Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferation. The Journal of Biological Chemistry. 280: 18211-20. PMID 15722552 DOI: 10.1074/Jbc.M501410200 |
0.454 |
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| 2004 |
Chen Q, Liang D, Yang T, Leone G, Overbeek PA. Distinct capacities of individual E2Fs to induce cell cycle re-entry in postmitotic lens fiber cells of transgenic mice. Developmental Neuroscience. 26: 435-45. PMID 15855772 DOI: 10.1159/000082285 |
0.429 |
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| 2004 |
Iavarone A, King ER, Dai XM, Leone G, Stanley ER, Lasorella A. Retinoblastoma promotes definitive erythropoiesis by repressing Id2 in fetal liver macrophages. Nature. 432: 1040-5. PMID 15616565 DOI: 10.1038/Nature03068 |
0.378 |
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| 2004 |
Yu L, Liu C, Bennett K, Wu YZ, Dai Z, Vandeusen J, Opavsky R, Raval A, Trikha P, Rodriguez B, Becknell B, Mao C, Lee S, Davuluri RV, Leone G, et al. A NotI-EcoRV promoter library for studies of genetic and epigenetic alterations in mouse models of human malignancies. Genomics. 84: 647-60. PMID 15475242 DOI: 10.1016/J.Ygeno.2004.06.010 |
0.369 |
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| 2004 |
Jiang Y, Saavedra HI, Holloway MP, Leone G, Altura RA. Aberrant regulation of survivin by the RB/E2F family of proteins. The Journal of Biological Chemistry. 279: 40511-20. PMID 15271987 DOI: 10.1074/Jbc.M404496200 |
0.533 |
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| 2004 |
Dai Z, Popkie AP, Zhu WG, Timmers CD, Raval A, Tannehill-Gregg S, Morrison CD, Auer H, Kratzke RA, Niehans G, Amatschek S, Sommergruber W, Leone GW, Rosol T, Otterson GA, et al. Bone morphogenetic protein 3B silencing in non-small-cell lung cancer. Oncogene. 23: 3521-9. PMID 15116090 DOI: 10.1038/Sj.Onc.1207441 |
0.371 |
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| 2004 |
Zhang J, Gray J, Wu L, Leone G, Rowan S, Cepko CL, Zhu X, Craft CM, Dyer MA. Rb regulates proliferation and rod photoreceptor development in the mouse retina. Nature Genetics. 36: 351-60. PMID 14991054 DOI: 10.1038/Ng1318 |
0.409 |
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| 2003 |
Cheng S, Hsia CY, Leone G, Liou HC. Cyclin E and Bcl-xL cooperatively induce cell cycle progression in c-Rel-/- B cells. Oncogene. 22: 8472-86. PMID 14627988 DOI: 10.1038/Sj.Onc.1206917 |
0.391 |
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| 2003 |
de Bruin A, Maiti B, Jakoi L, Timmers C, Buerki R, Leone G. Identification and characterization of E2F7, a novel mammalian E2F family member capable of blocking cellular proliferation. The Journal of Biological Chemistry. 278: 42041-9. PMID 12893818 DOI: 10.1074/Jbc.M308105200 |
0.423 |
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| 2003 |
de Bruin A, Wu L, Saavedra HI, Wilson P, Yang Y, Rosol TJ, Weinstein M, Robinson ML, Leone G. Rb function in extraembryonic lineages suppresses apoptosis in the CNS of Rb-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 100: 6546-51. PMID 12732721 DOI: 10.1073/Pnas.1031853100 |
0.391 |
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| 2003 |
Saavedra HI, Maiti B, Timmers C, Altura R, Tokuyama Y, Fukasawa K, Leone G. Inactivation of E2F3 results in centrosome amplification. Cancer Cell. 3: 333-46. PMID 12726860 DOI: 10.1016/S1535-6108(03)00083-7 |
0.433 |
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| 2003 |
Wu L, de Bruin A, Saavedra HI, Starovic M, Trimboli A, Yang Y, Opavska J, Wilson P, Thompson JC, Ostrowski MC, Rosol TJ, Woollett LA, Weinstein M, Cross JC, Robinson ML, ... Leone G, et al. Extra-embryonic function of Rb is essential for embryonic development and viability. Nature. 421: 942-7. PMID 12607001 DOI: 10.1038/Nature01417 |
0.445 |
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| 2002 |
de la Puente A, Hall J, Wu YZ, Leone G, Peters J, Yoon BJ, Soloway P, Plass C. Structural characterization of Rasgrf1 and a novel linked imprinted locus. Gene. 291: 287-97. PMID 12095702 DOI: 10.1016/S0378-1119(02)00601-7 |
0.319 |
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| 2002 |
Saavedra HI, Wu L, de Bruin A, Timmers C, Rosol TJ, Weinstein M, Robinson ML, Leone G. Specificity of E2F1, E2F2, and E2F3 in mediating phenotypes induced by loss of Rb. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 13: 215-25. PMID 12065245 |
0.302 |
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| 2002 |
Cook JG, Park CH, Burke TW, Leone G, DeGregori J, Engel A, Nevins JR. Analysis of Cdc6 function in the assembly of mammalian prereplication complexes. Proceedings of the National Academy of Sciences of the United States of America. 99: 1347-52. PMID 11805305 DOI: 10.1073/Pnas.032677499 |
0.397 |
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| 2002 |
Lan Z, Sever-Chroneos Z, Strobeck MW, Park CH, Baskaran R, Edelmann W, Leone G, Knudsen ES. DNA damage invokes mismatch repair-dependent cyclin D1 attenuation and retinoblastoma signaling pathways to inhibit CDK2. The Journal of Biological Chemistry. 277: 8372-81. PMID 11726663 DOI: 10.1074/Jbc.M108906200 |
0.369 |
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| 2001 |
Wu L, Timmers C, Maiti B, Saavedra HI, Sang L, Chong GT, Nuckolls F, Giangrande P, Wright FA, Field SJ, Greenberg ME, Orkin S, Nevins JR, Robinson ML, Leone G. The E2F1-3 transcription factors are essential for cellular proliferation. Nature. 414: 457-62. PMID 11719808 DOI: 10.1038/35106593 |
0.462 |
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| 2001 |
Tanner SM, Austin JL, Leone G, Rush LJ, Plass C, Heinonen K, Mrózek K, Sill H, Knuutila S, Kolitz JE, Archer KJ, Caligiuri MA, Bloomfield CD, de La Chapelle A. BAALC, the human member of a novel mammalian neuroectoderm gene lineage, is implicated in hematopoiesis and acute leukemia. Proceedings of the National Academy of Sciences of the United States of America. 98: 13901-6. PMID 11707601 DOI: 10.1073/Pnas.241525498 |
0.391 |
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| 2001 |
Leone G, Sears R, Huang E, Rempel R, Nuckolls F, Park CH, Giangrande P, Wu L, Saavedra HI, Field SJ, Thompson MA, Yang H, Fujiwara Y, Greenberg ME, Orkin S, et al. Myc requires distinct E2F activities to induce S phase and apoptosis. Molecular Cell. 8: 105-13. PMID 11511364 DOI: 10.1016/S1097-2765(01)00275-1 |
0.425 |
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| 2001 |
Ishida S, Huang E, Zuzan H, Spang R, Leone G, West M, Nevins JR. Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis. Molecular and Cellular Biology. 21: 4684-99. PMID 11416145 DOI: 10.1128/Mcb.21.14.4684-4699.2001 |
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| 2000 |
Adams MR, Sears R, Nuckolls F, Leone G, Nevins JR. Complex transcriptional regulatory mechanisms control expression of the E2F3 locus. Molecular and Cellular Biology. 20: 3633-9. PMID 10779353 DOI: 10.1128/Mcb.20.10.3633-3639.2000 |
0.425 |
|
| 2000 |
Leone G, Nuckolls F, Ishida S, Adams M, Sears R, Jakoi L, Miron A, Nevins JR. Identification of a novel E2F3 product suggests a mechanism for determining specificity of repression by Rb proteins. Molecular and Cellular Biology. 20: 3626-32. PMID 10779352 DOI: 10.1128/Mcb.20.10.3626-3632.2000 |
0.44 |
|
| 1999 |
Leone G, DeGregori J, Jakoi L, Cook JG, Nevins JR. Collaborative role of E2F transcriptional activity and G1 cyclin- dependent kinase activity in the induction of S phase Proceedings of the National Academy of Sciences of the United States of America. 96: 6626-6631. PMID 10359762 DOI: 10.1073/Pnas.96.12.6626 |
0.337 |
|
| 1998 |
Leone G, DeGregori J, Yan Z, Jakoi L, Ishida S, Williams RS, Nevins JR. E2F3 activity is regulated during the cell cycle and is required for the induction of S phase Genes and Development. 12: 2120-2130. PMID 9679057 DOI: 10.1101/Gad.12.14.2120 |
0.447 |
|
| 1998 |
Yan Z, Degregori J, Shohet R, Leone G, Stillman B, Nevins JR, Williams RS. Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells Proceedings of the National Academy of Sciences of the United States of America. 95: 3603-3608. PMID 9520412 DOI: 10.1073/Pnas.95.7.3603 |
0.457 |
|
| 1997 |
Nevins JR, Leone G, DeGregori J, Jakoi L. Role of the Rb/E2F pathway in cell growth control Journal of Cellular Physiology. 173: 233-236. PMID 9365528 DOI: 10.1002/(Sici)1097-4652(199711)173:2<233::Aid-Jcp27>3.0.Co;2-F |
0.352 |
|
| 1997 |
Nevins JR, Degregori J, Jakoi L, Leone G. Functional analysis of E2F transcription factor Methods in Enzymology. 283: 205-219. PMID 9251021 DOI: 10.1016/S0076-6879(97)83017-0 |
0.444 |
|
| 1997 |
Degregori J, Leone G, Miron A, Jakoi L, Nevins JR. Distinct roles for E2F proteins in cell growth control and apoptosis Proceedings of the National Academy of Sciences of the United States of America. 94: 7245-7250. PMID 9207076 DOI: 10.1073/Pnas.94.14.7245 |
0.453 |
|
| 1997 |
Leone G, DeGregori J, Sears R, Jakoi L, Nevins JR. Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F Nature. 387: 422-426. PMID 9163430 DOI: 10.1038/387422A0 |
0.332 |
|
| 1996 |
Ohtani K, DeGregori J, Leone G, Herendeen DR, Kelly TJ, Nevins JR. Expression of the HsOrc1 gene, a human ORC1 homolog, is regulated by cell proliferation via the E2F transcription factor. Molecular and Cellular Biology. 16: 6977-84. PMID 8943353 DOI: 10.1128/Mcb.16.12.6977 |
0.468 |
|
| 1996 |
Smith EJ, Leone G, DeGregori J, Jakoi L, Nevins JR. The accumulation of an E2F-p130 transcriptional repressor distinguishes a G0 cell state from a G1 cell state Molecular and Cellular Biology. 16: 6965-6976. PMID 8943352 DOI: 10.1128/Mcb.16.12.6965 |
0.41 |
|
| 1995 |
DeGregori J, Leone G, Ohtani K, Miron A, Nevins JR. E2F-1 accumulation bypasses a G1 arrest resulting from the inhibition of G1 cyclin-dependent kinase activity Genes and Development. 9: 2783-2887. PMID 7498785 DOI: 10.1101/Gad.9.23.2873 |
0.316 |
|
| 1994 |
Lee PWK, Leone G. Reovirus protein sigma 1: from cell attachment to protein oligomerization and folding mechanisms. Bioessays. 16: 199-206. PMID 8166674 DOI: 10.1002/Bies.950160311 |
0.342 |
|
| 1991 |
Duncan R, Horne D, Strong JE, Leone G, Pon RT, Yeung MC, Lee PW. Conformational and functional analysis of the C-terminal globular head of the reovirus cell attachment protein. Virology. 182: 810-9. PMID 2024499 DOI: 10.1016/0042-6822(91)90622-I |
0.333 |
|
| 1991 |
Leone G, Mah DCW, Lee PWK. The incorporation of reovirus cell attachment protein σ1 into virions requires the N-terminal hydrophobic tail and the adjacent heptad repeat region Virology. 182: 346-350. PMID 2024470 DOI: 10.1016/0042-6822(91)90678-5 |
0.327 |
|
| 1991 |
Leone G, Duncan R, Lee PW. Trimerization of the reovirus cell attachment protein (sigma 1) induces conformational changes in sigma 1 necessary for its cell-binding function. Virology. 184: 758-61. PMID 1887593 DOI: 10.1016/0042-6822(91)90447-J |
0.331 |
|
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