David Gailani - Publications

Affiliations: 
Vanderbilt University, Nashville, TN 
Area:
Pathology, Molecular Biology, Biochemistry

182 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Shamanaev A, Dickeson SK, Ivanov I, Litvak M, Sun MF, Kumar S, Cheng Q, Srivastava P, He TZ, Gailani D. Mechanisms involved in hereditary angioedema with normal C1-inhibitor activity. Frontiers in Physiology. 14: 1146834. PMID 37288434 DOI: 10.3389/fphys.2023.1146834  0.34
2023 Shamanaev A, Litvak M, Ivanov I, Srivastava P, Sun MF, Dickeson SK, Kumar S, He TZ, Gailani D. Factor XII Structure-Function Relationships. Seminars in Thrombosis and Hemostasis. PMID 37276883 DOI: 10.1055/s-0043-1769509  0.379
2023 Shamanaev A, Litvak M, Cheng Q, Ponczek M, Dickeson SK, Smith SA, Morrissey JH, Gailani D. A Site on Factor XII Required for Productive Interactions with Polyphosphate. Journal of Thrombosis and Haemostasis : Jth. PMID 36863563 DOI: 10.1016/j.jtha.2023.02.014  0.386
2022 Mohammed BM, Cheng Q, Gailani D. A demonstration of factor XI contributing to hemostasis in the absence of factor XII. Research and Practice in Thrombosis and Haemostasis. 6: e12841. PMID 36426234 DOI: 10.1002/rth2.12841  0.326
2022 Jordan KR, Wyatt CR, Fallon ME, Woltjer R, Neuwelt EA, Cheng Q, Gailani D, Lorentz C, Tucker EI, McCarty OJT, Hinds MT, Nguyen KP. Pharmacological reduction of coagulation factor XI reduces macrophage accumulation and accelerates deep vein thrombosis resolution in a mouse model of venous thrombosis. Journal of Thrombosis and Haemostasis : Jth. PMID 35638310 DOI: 10.1111/jth.15777  0.305
2022 Kuder H, Dickeson SK, Brooks MB, Kehl A, Müller E, Gailani D, Giger U. A Common Missense Variant Causing Factor XI Deficiency and Increased Bleeding Tendency in Maine Coon Cats. Genes. 13. PMID 35627175 DOI: 10.3390/genes13050792  0.302
2022 Shamanaev A, Ivanov I, Sun MF, Litvak M, Srivastava P, Mohammed BM, Shaban R, Maddur A, Verhamme IM, McCarty OJT, Law RHP, Gailani D. A Model for Surface-Dependent Factor XII Activation: The Roles of Factor XII Heavy Chain Domains. Blood Advances. PMID 35086137 DOI: 10.1182/bloodadvances.2021005976  0.311
2022 Morla S, Deguchi H, Zilberman-Rudenko J, Gruber A, McCarty OJT, Srivastava P, Gailani D, Griffin JH. Skeletal muscle myosin promotes coagulation by binding factor XI via its A3 domain and enhancing thrombin-induced factor XI activation. The Journal of Biological Chemistry. 101567. PMID 35007530 DOI: 10.1016/j.jbc.2022.101567  0.329
2021 Hsu C, Hutt E, Bloomfield DM, Gailani D, Weitz JI. Factor XI Inhibition to Uncouple Thrombosis From Hemostasis: JACC Review Topic of the Week. Journal of the American College of Cardiology. 78: 625-631. PMID 34353538 DOI: 10.1016/j.jacc.2021.06.010  0.325
2021 Puy C, Pang J, Reitsma SE, Lorentz CU, Tucker EI, Gailani D, Gruber A, Lupu F, McCarty OJT. Cross-Talk between the Complement Pathway and the Contact Activation System of Coagulation: Activated Factor XI Neutralizes Complement Factor H. Journal of Immunology (Baltimore, Md. : 1950). 206: 1784-1792. PMID 33811105 DOI: 10.4049/jimmunol.2000398  0.405
2021 Reitsma SE, Pang J, Raghunathan V, Shatzel JJ, Lorentz CU, Tucker EI, Gruber A, Gailani D, McCarty OJT, Puy C. Role of platelets in regulating activated coagulation factor XI activity. American Journal of Physiology. Cell Physiology. PMID 33471623 DOI: 10.1152/ajpcell.00056.2020  0.326
2021 Ngo ATP, Jordan KR, Mueller PA, Hagen MW, Reitsma SE, Puy C, Revenko AS, Lorentz CU, Tucker EI, Cheng Q, Hinds MT, Fazio S, Monia BP, Gailani D, Gruber A, et al. Pharmacological targeting of coagulation factor XI mitigates the development of experimental atherosclerosis in low-density lipoprotein receptor-deficient mice. Journal of Thrombosis and Haemostasis : Jth. PMID 33421301 DOI: 10.1111/jth.15236  0.32
2021 Kearney KJ, Butler J, Posada OM, Wilson C, Heal S, Ali M, Hardy L, Ahnström J, Gailani D, Foster R, Hethershaw E, Longstaff C, Philippou H. Kallikrein directly interacts with and activates Factor IX, resulting in thrombin generation and fibrin formation independent of Factor XI. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33397811 DOI: 10.1073/pnas.2014810118  0.391
2020 Ponczek MB, Shamanaev A, LaPlace A, Dickeson SK, Srivastava P, Sun MF, Gruber A, Kastrup C, Emsley J, Gailani D. The evolution of factor XI and the kallikrein-kinin system. Blood Advances. 4: 6135-6147. PMID 33351111 DOI: 10.1182/bloodadvances.2020002456  0.378
2020 Shamanaev A, Emsley J, Gailani D. Proteolytic Activity of Contact Factor Zymogens. Journal of Thrombosis and Haemostasis : Jth. PMID 33107140 DOI: 10.1111/jth.15149  0.321
2020 Srivastava P, Gailani D. The rebirth of the contact pathway: a new therapeutic target. Current Opinion in Hematology. 27: 311-319. PMID 32740037 DOI: 10.1097/Moh.0000000000000603  0.378
2020 Wallisch M, Lorentz CU, Lakshmanan HHS, Johnson J, Carris MR, Puy C, Gailani D, Hinds MT, McCarty OJT, Gruber A, Tucker EI. Antibody inhibition of contact factor XII reduces platelet deposition in a model of extracorporeal membrane oxygenator perfusion in nonhuman primates. Research and Practice in Thrombosis and Haemostasis. 4: 205-216. PMID 32110750 DOI: 10.1002/rth2.12309  0.341
2020 Mohammed BM, Monroe DM, Gailani D. Mouse models of hemostasis. Platelets. 1-6. PMID 31992118 DOI: 10.1080/09537104.2020.1719056  0.339
2020 Grover SP, Schmedes CM, Auriemma AC, Butler E, Parrish ML, Miszta A, Cleuren AC, Visser M, Heitmeier S, Posma JJ, Spronk HM, Antoniak S, Wolberg AS, Pawlinski R, Gailani D, et al. Differential roles of factors IX and XI in murine placenta and hemostasis under conditions of low tissue factor. Blood Advances. 4: 207-216. PMID 31935292 DOI: 10.1182/Bloodadvances.2019000921  0.418
2019 Gailani D, Emsley J. Toward a better understanding of factor XI activation. Journal of Thrombosis and Haemostasis : Jth. 17: 2016-2018. PMID 31797540 DOI: 10.1111/Jth.14631  0.438
2019 Gailani D. Factor IX for treating factor XI deficiency? Blood. 134: 501-502. PMID 31395584 DOI: 10.1182/blood.2019001826  0.311
2019 Puy C, Ngo ATP, Pang J, Keshari RS, Hagen MW, Hinds MT, Gailani D, Gruber A, Lupu F, McCarty OJT. Endothelial PAI-1 (Plasminogen Activator Inhibitor-1) Blocks the Intrinsic Pathway of Coagulation, Inducing the Clearance and Degradation of FXIa (Activated Factor XI). Arteriosclerosis, Thrombosis, and Vascular Biology. 39: 1390-1401. PMID 31242030 DOI: 10.1161/Atvbaha.119.312619  0.451
2019 Mohammed BM, Cheng Q, Matafonov A, Verhamme IM, Emsley J, McCrae KR, McCarty OJT, Gruber A, Gailani D. A non-circulating pool of factor XI associated with glycosaminoglycans in mice. Journal of Thrombosis and Haemostasis : Jth. PMID 31125187 DOI: 10.1111/Jth.14494  0.405
2019 Garnett ER, Lomax JE, Mohammed B, Gailani D, Sheehan JP, Raines RT. Phenotype of ribonuclease 1 deficiency in mice. Rna (New York, N.Y.). PMID 31053653 DOI: 10.1261/Rna.070433.119  0.313
2019 Silasi R, Keshari RS, Lupu C, Van Rensburg WJ, Chaaban H, Regmi G, Shamanaev A, Shatzel JJ, Puy C, Lorentz CU, Tucker EI, Gailani D, Gruber A, McCarty OJT, Lupu F. Inhibition of contact-mediated activation of factor XI protects baboons against -induced organ damage and death. Blood Advances. 3: 658-669. PMID 30808684 DOI: 10.1182/Bloodadvances.2018029983  0.407
2019 Lorentz CU, Verbout NG, Wallisch M, Hagen MW, Shatzel JJ, Olson SR, Puy C, Hinds MT, McCarty OJT, Gailani D, Gruber A, Tucker EI. Contact Activation Inhibitor and Factor XI Antibody, AB023, Produces Safe, Dose-Dependent Anticoagulation in a Phase 1 First-In-Human Trial. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA118312328. PMID 30700130 DOI: 10.1161/Atvbaha.118.312328  0.393
2018 Ivanov I, Matafonov A, Sun MF, Mohammed BM, Cheng Q, Dickeson SK, Kundu S, Verhamme IM, Gruber A, McCrae K, Gailani D. A mechanism for hereditary angioedema with normal C1-inhibitor: an inhibitory regulatory role for the factor XII heavy chain. Blood. PMID 30591525 DOI: 10.1182/Blood-2018-06-860270  0.485
2018 Zilberman-Rudenko J, Reitsma SE, Puy C, Rigg RA, Smith SA, Tucker EI, Silasi R, Merkulova A, McCrae KR, Maas C, Urbanus RT, Gailani D, Morrissey JH, Gruber A, Lupu F, et al. Factor XII Activation Promotes Platelet Consumption in the Presence of Bacterial-Type Long-Chain Polyphosphate In Vitro and In Vivo. Arteriosclerosis, Thrombosis, and Vascular Biology. 38: 1748-1760. PMID 30354195 DOI: 10.1161/Atvbaha.118.311193  0.412
2018 Tillman BF, Gruber A, McCarty OJT, Gailani D. Plasma contact factors as therapeutic targets. Blood Reviews. PMID 30075986 DOI: 10.1016/J.Blre.2018.04.001  0.467
2018 Mohammed BM, Cheng Q, Matafonov A, Monroe DM, Meijers JCM, Gailani D. Factor XI promotes hemostasis in factor IX deficient mice. Journal of Thrombosis and Haemostasis : Jth. PMID 30007049 DOI: 10.1111/Jth.14243  0.399
2018 Popescu NI, Silasi R, Keshari RS, Girton A, Burgett T, Zeerleder SS, Gailani D, Gruber A, Lupu F, Coggeshall KM. Peptidoglycan induces disseminated intravascular coagulation in baboons through activation of both coagulation pathways. Blood. PMID 29921614 DOI: 10.1182/Blood-2017-10-813618  0.302
2018 Lorentz CU, Verbout NG, Cao Z, Liu L, Hinds MT, McCarty OJT, Ivanov I, Tucker EI, Gailani D, Gruber A. Factor XI contributes to myocardial ischemia-reperfusion injury in mice. Blood Advances. 2: 85-88. PMID 29365314 DOI: 10.1182/Bloodadvances.2017004879  0.315
2018 Mohammed BM, Ivanov I, Matafonov A, Emsley J, Gailani D. Activity of Factor XII-Locarno. Research and Practice in Thrombosis and Haemostasis. 2: 168-173. PMID 29354798 DOI: 10.1002/rth2.12054  0.373
2018 Mohammed BM, Matafonov A, Ivanov I, Sun MF, Cheng Q, Dickeson SK, Li C, Sun D, Verhamme IM, Emsley J, Gailani D. An update on factor XI structure and function. Thrombosis Research. 161: 94-105. PMID 29223926 DOI: 10.1016/J.Thromres.2017.10.008  0.447
2018 Puy C, Ngo A, Gailani D, Gruber A, McCarty OJ. Abstract 362: Plasminogen Activator Inhibitor 1 Forms a Complex With FXIa on the Surface of Endothelial Cells, Blocking Its Activity and Inducing the Clearance, Internalization and Degradation of FXIa Arteriosclerosis, Thrombosis, and Vascular Biology. 38. DOI: 10.1161/Atvb.38.Suppl_1.362  0.346
2018 Zilberman-Rudenko J, Reitsma SE, Puy C, Smith SA, Wiesenekker CP, Tucker EI, Travers RJ, Maas C, Urbanus RT, Gailani D, Schmaier AH, Lupu F, Morrissey JH, Gruber A, McCarty OJ. Abstract 091: Coagulation Factor XII Promotes Platelet Consumption in the Presence of Microbial Polyphosphate Under Shear Flow Arteriosclerosis, Thrombosis, and Vascular Biology. 38. DOI: 10.1161/Atvb.38.Suppl_1.091  0.374
2018 Zilberman-Rudenko J, Reitsma SE, Puy C, Smith SA, Wiesenekker CP, Tucker EI, Travers RJ, Maas C, Urbanus RT, Gailani D, Schmaier AH, Lupu F, Morrissey JH, Gruber A, McCarty OJ. Abstract 037: Coagulation Factor XII Promotes Platelet Consumption in the Presence of Microbial Polyphosphate Under Shear Flow Arteriosclerosis, Thrombosis, and Vascular Biology. 38. DOI: 10.1161/Atvb.38.Suppl_1.037  0.374
2017 Garland KS, Reitsma SE, Shirai T, Zilberman-Rudenko J, Tucker EI, Gailani D, Gruber A, McCarty OJT, Puy C. Removal of the C-Terminal Domains of ADAMTS13 by Activated Coagulation Factor XI induces Platelet Adhesion on Endothelial Cells under Flow Conditions. Frontiers in Medicine. 4: 232. PMID 29326937 DOI: 10.3389/Fmed.2017.00232  0.425
2017 Tillman B, Gailani D. Inhibition of Factors XI and XII for Prevention of Thrombosis Induced by Artificial Surfaces. Seminars in Thrombosis and Hemostasis. PMID 28898903 DOI: 10.1055/S-0037-1603937  0.422
2017 Woodruff RS, Ivanov I, Verhamme IM, Sun MF, Gailani D, Sullenger BA. Generation and characterization of aptamers targeting factor XIa. Thrombosis Research. 156: 134-141. PMID 28644959 DOI: 10.1016/J.Thromres.2017.06.015  0.374
2017 Ivanov I, Matafonov A, Gailani D. Single-chain factor XII: a new form of activated factor XII. Current Opinion in Hematology. PMID 28604413 DOI: 10.1097/Moh.0000000000000363  0.441
2017 Ivanov I, Sun MF, Dickeson SK, Puy C, McCarty OJ, Gruber A, Matafonov A, Gailani D. Nucleic acids as cofactors for factor XI and prekallikrein activation: Different roles for high-molecular-weight kininogen. Thrombosis and Haemostasis. PMID 28124063 DOI: 10.1160/Th16-09-0691  0.399
2017 Ivanov I, Matafonov A, Sun MF, Cheng Q, Dickeson SK, Verhamme IM, Emsley J, Gailani D. Proteolytic properties of single-chain factor XII: a mechanism for triggering contact activation. Blood. PMID 28069606 DOI: 10.1182/Blood-2016-10-744110  0.418
2017 Tillman BF, Matafonov A, Kingeter AJ, Shah AS, Gailani D. Effects of Plasma Exchange and Heparin Concentration on the Serotonin Release Assay in Heparin-Induced Thrombocytopenia The Journal of Applied Laboratory Medicine: An Aacc Publication. 2: 380-385. DOI: 10.1373/Jalm.2017.023929  0.364
2016 Puy C, Tucker EI, Ivanov IS, Gailani D, Smith SA, Morrissey JH, Gruber A, McCarty OJ. Platelet-Derived Short-Chain Polyphosphates Enhance the Inactivation of Tissue Factor Pathway Inhibitor by Activated Coagulation Factor XI. Plos One. 11: e0165172. PMID 27764259 DOI: 10.1371/Journal.Pone.0165172  0.483
2016 Wheeler AP, Gailani D. The Intrinsic Pathway of Coagulation as a Target for Antithrombotic Therapy. Hematology/Oncology Clinics of North America. 30: 1099-114. PMID 27637310 DOI: 10.1016/J.Hoc.2016.05.007  0.462
2016 Wheeler AP, Gailani D. Why Factor XI Deficiency is a Clinical Concern. Expert Review of Hematology. PMID 27216469 DOI: 10.1080/17474086.2016.1191944  0.342
2016 Gailani D, Gruber A. Factor XI as a Therapeutic Target. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 27174099 DOI: 10.1161/Atvbaha.116.306925  0.469
2016 Bane CE, Ivanov I, Matafonov A, Boyd KL, Cheng Q, Sherwood ER, Tucker EI, Smiley ST, McCarty OJ, Gruber A, Gailani D. Factor XI Deficiency Alters the Cytokine Response and Activation of Contact Proteases during Polymicrobial Sepsis in Mice. Plos One. 11: e0152968. PMID 27046148 DOI: 10.1371/Journal.Pone.0152968  0.457
2016 Kokoye Y, Ivanov I, Cheng Q, Matafonov A, Dickeson SK, Mason S, Sexton DJ, Renné T, McCrae K, Feener EP, Gailani D. A comparison of the effects of factor XII deficiency and prekallikrein deficiency on thrombus formation. Thrombosis Research. 140: 118-24. PMID 26950760 DOI: 10.1016/J.Thromres.2016.02.020  0.421
2016 Shnerb Ganor R, Harats D, Schiby G, Gailani D, Levkovitz H, Avivi C, Tamarin I, Shaish A, Salomon O. Factor XI Deficiency Protects Against Atherogenesis in Apolipoprotein E/Factor XI Double Knockout Mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 36: 475-81. PMID 26800563 DOI: 10.1161/Atvbaha.115.306954  0.328
2016 Zilberman-Rudenko J, Itakura A, Wiesenekker CP, Vetter R, Maas C, Gailani D, Tucker EI, Gruber A, Gerdes C, McCarty OJ. Coagulation Factor XI Promotes Distal Platelet Activation and Single Platelet Consumption in the Bloodstream Under Shear Flow. Arteriosclerosis, Thrombosis, and Vascular Biology. 36: 510-7. PMID 26769048 DOI: 10.1161/ATVBAHA.115.307034  0.346
2016 Mehta AY, Mohammed BM, Martin EJ, Brophy DF, Gailani D, Desai UR. Allosterism-based Simultaneous, Dual Anticoagulant and Antiplatelet Action Allosteric Inhibitor Targeting the Glycoprotein Ibα and Heparin-Binding Site of Thrombin. Journal of Thrombosis and Haemostasis : Jth. PMID 26748875 DOI: 10.1111/Jth.13254  0.339
2015 Gailani D, Bane CE, Gruber A. Factor XI and contact activation as targets for antithrombotic therapy. Journal of Thrombosis and Haemostasis : Jth. PMID 25976012 DOI: 10.1111/Jth.13005  0.431
2015 Al-Horani RA, Gailani D, Desai UR. Allosteric inhibition of factor XIa. Sulfated non-saccharide glycosaminoglycan mimetics as promising anticoagulants. Thrombosis Research. 136: 379-87. PMID 25935648 DOI: 10.1016/J.Thromres.2015.04.017  0.485
2015 Gilbert L, Paroskie A, Gailani D, Debaun MR, Sidonio RF. Haemophilia A carriers experience reduced health-related quality of life. Haemophilia : the Official Journal of the World Federation of Hemophilia. 21: 761-5. PMID 25930174 DOI: 10.1111/Hae.12690  0.309
2015 Büller HR, Gailani D, Weitz JI. Factor XI antisense oligonucleotide for venous thrombosis. The New England Journal of Medicine. 372: 1672. PMID 25901434 DOI: 10.1056/Nejmc1503223  0.427
2015 Sparkenbaugh EM, Chantrathammachart P, Wang S, Jonas W, Kirchhofer D, Gailani D, Gruber A, Kasthuri R, Key NS, Mackman N, Pawlinski R. Excess of heme induces tissue factor-dependent activation of coagulation in mice. Haematologica. 100: 308-14. PMID 25596265 DOI: 10.3324/Haematol.2014.114728  0.46
2015 Puy C, Tucker EI, Matafonov A, Cheng Q, Zientek KD, Gailani D, Gruber A, McCarty OJ. Activated factor XI increases the procoagulant activity of the extrinsic pathway by inactivating tissue factor pathway inhibitor. Blood. 125: 1488-96. PMID 25587039 DOI: 10.1182/blood-2014-10-604587  0.393
2015 Büller HR, Bethune C, Bhanot S, Gailani D, Monia BP, Raskob GE, Segers A, Verhamme P, Weitz JI. Factor XI antisense oligonucleotide for prevention of venous thrombosis. The New England Journal of Medicine. 372: 232-40. PMID 25482425 DOI: 10.1056/Nejmoa1405760  0.421
2015 Gailani D, Cheng Q, Ivanov IS. Murine models in the evaluation of heparan sulfate-based anticoagulants. Methods in Molecular Biology (Clifton, N.J.). 1229: 483-96. PMID 25325974 DOI: 10.1007/978-1-4939-1714-3_37  0.331
2015 Mason SD, Kenniston J, Comeau SR, Conley GP, Kastrapeli N, Kopacz KJ, Lindberg AP, Cosic J, Kivaa M, Qiu JA, Faucette R, Sexton D, Tenhoor C, Gailani D, Dickeson SK, et al. Discovery and Characterization of a Highly Specific Antibody Inhibitor of Factor XIIa, and the Subsequent Generation of a Factor XIIa/Plasma Kallikrein Bispecific Antibody Blood. 126: 2268-2268. DOI: 10.1182/Blood.V126.23.2268.2268  0.426
2014 Gailani D. Future prospects for contact factors as therapeutic targets. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 2014: 52-9. PMID 25696834 DOI: 10.1182/Asheducation-2014.1.52  0.461
2014 Sosa R, Gailani D, Neff AT. Development of anti-factor XIII antibodies in a patient with hereditary factor XIII deficiency receiving therapy for chronic hepatitis C. Haemophilia : the Official Journal of the World Federation of Hemophilia. 20: e429-32. PMID 25333572 DOI: 10.1111/Hae.12537  0.331
2014 Wang J, Matafonov A, Madkhali H, Mahdi F, Watson D, Schmaier AH, Gailani D, Shariat-Madar Z. Prolylcarboxypeptidase independently activates plasma prekallikrein (Fletcher factor) Current Molecular Medicine. 14: 1173-1185. PMID 25324000 DOI: 10.2174/1566524014666141015153519  0.412
2014 Gilbert L, Rollins L, Hilmes M, Luo Y, Gailani D, Debaun MR, Sidonio RF. Haemophilia A carriers demonstrate pathological and radiological evidence of structural joint changes. Haemophilia : the Official Journal of the World Federation of Hemophilia. 20: e426-9. PMID 25251752 DOI: 10.1111/Hae.12535  0.313
2014 Bane CE, Gailani D. Factor XI as a target for antithrombotic therapy. Drug Discovery Today. 19: 1454-8. PMID 24886766 DOI: 10.1016/J.Drudis.2014.05.018  0.348
2014 Gailani D, Geng Y, Verhamme I, Sun MF, Bajaj SP, Messer A, Emsley J. The mechanism underlying activation of factor IX by factor XIa. Thrombosis Research. 133: S48-51. PMID 24759143 DOI: 10.1016/J.Thromres.2014.03.020  0.662
2014 Matafonov A, Leung PY, Gailani AE, Grach SL, Puy C, Cheng Q, Sun MF, McCarty OJ, Tucker EI, Kataoka H, Renné T, Morrissey JH, Gruber A, Gailani D. Factor XII inhibition reduces thrombus formation in a primate thrombosis model. Blood. 123: 1739-46. PMID 24408325 DOI: 10.1182/Blood-2013-04-499111  0.432
2014 Matafonov A, Ivanov IS, Sun M, Gailani D. Coagulation Factor XI and Factor XII in DNA-Induced Thrombin Generation Blood. 124: 581-581. DOI: 10.1182/Blood.V124.21.581.581  0.415
2013 Matafonov A, Cheng Q, Geng Y, Verhamme IM, Umunakwe O, Tucker EI, Sun MF, Serebrov V, Gruber A, Gailani D. Evidence for factor IX-independent roles for factor XIa in blood coagulation. Journal of Thrombosis and Haemostasis : Jth. 11: 2118-27. PMID 24152424 DOI: 10.1111/Jth.12435  0.664
2013 Geng Y, Verhamme IM, Smith SA, Cheng Q, Sun M, Sheehan JP, Morrissey JH, Gailani D. Factor XI anion-binding sites are required for productive interactions with polyphosphate. Journal of Thrombosis and Haemostasis : Jth. 11: 2020-8. PMID 24118982 DOI: 10.1111/Jth.12414  0.611
2013 Sosa IR, Ellery P, Mast A, Neff AT, Gailani D. Acquired factor V deficiency in a patient without evidence of a classical inhibitor Haemophilia. 20. PMID 24118596 DOI: 10.1111/Hae.12280  0.457
2013 Puy C, Tucker EI, Wong ZC, Gailani D, Smith SA, Choi SH, Morrissey JH, Gruber A, McCarty OJ. Factor XII promotes blood coagulation independent of factor XI in the presence of long-chain polyphosphates. Journal of Thrombosis and Haemostasis : Jth. 11: 1341-52. PMID 23659638 DOI: 10.1111/Jth.12295  0.434
2013 Geng Y, Verhamme IM, Sun MF, Bajaj SP, Emsley J, Gailani D. Analysis of the factor XI variant Arg184Gly suggests a structural basis for factor IX binding to factor XIa. Journal of Thrombosis and Haemostasis : Jth. 11: 1374-84. PMID 23617568 DOI: 10.1111/Jth.12275  0.641
2013 Crosby JR, Marzec U, Revenko AS, Zhao C, Gao D, Matafonov A, Gailani D, MacLeod AR, Tucker EI, Gruber A, Hanson SR, Monia BP. Antithrombotic effect of antisense factor XI oligonucleotide treatment in primates. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 1670-8. PMID 23559626 DOI: 10.1161/Atvbaha.113.301282  0.473
2013 Geng Y, Verhamme IM, Smith SB, Sun MF, Matafonov A, Cheng Q, Smith SA, Morrissey JH, Gailani D. The dimeric structure of factor XI and zymogen activation. Blood. 121: 3962-9. PMID 23515926 DOI: 10.1182/Blood-2012-12-473629  0.641
2013 Karuturi R, Al-Horani RA, Mehta SC, Gailani D, Desai UR. Discovery of allosteric modulators of factor XIa by targeting hydrophobic domains adjacent to its heparin-binding site. Journal of Medicinal Chemistry. 56: 2415-28. PMID 23451707 DOI: 10.1021/Jm301757V  0.36
2013 Al-Horani RA, Ponnusamy P, Mehta AY, Gailani D, Desai UR. Sulfated pentagalloylglucoside is a potent, allosteric, and selective inhibitor of factor XIa. Journal of Medicinal Chemistry. 56: 867-78. PMID 23316863 DOI: 10.1021/Jm301338Q  0.418
2013 Duvernay M, Young S, Gailani D, Schoenecker J, Hamm HE, Hamm H. Protease-activated receptor (PAR) 1 and PAR4 differentially regulate factor V expression from human platelets. Molecular Pharmacology. 83: 781-92. PMID 23307185 DOI: 10.1124/Mol.112.083477  0.386
2013 Bane CE, Boyd KL, Tucker EI, Smiley ST, Gruber A, Gailani D. Factor XI Deficiency Reduces The Inflammatory Response To Polymicrobial Sepsis In Mice Blood. 122: 201-201. DOI: 10.1182/Blood.V122.21.201.201  0.382
2013 Tricarico N, Davis M, Gailani D, Casanova H, Leung S, Haglund N, Maltais S, Lenihan D. Factors Modifying Risk of Bleeding in Patients with Continuous Flow Left Ventricular Assist Devices Journal of Heart and Lung Transplantation. 32. DOI: 10.1016/J.Healun.2013.01.732  0.333
2012 Leung PY, Hurst S, Berny-Lang MA, Verbout NG, Gailani D, Tucker EI, Wang RK, McCarty OJ, Gruber A. Inhibition of Factor XII-Mediated Activation of Factor XI Provides Protection Against Experimental Acute Ischemic Stroke in Mice. Translational Stroke Research. 3: 381-9. PMID 23634198 DOI: 10.1007/S12975-012-0186-5  0.412
2012 Geng Y, Verhamme IM, Messer A, Sun MF, Smith SB, Bajaj SP, Gailani D. A sequential mechanism for exosite-mediated factor IX activation by factor XIa. The Journal of Biological Chemistry. 287: 38200-9. PMID 22961984 DOI: 10.1074/Jbc.M112.376343  0.601
2012 Rabey FM, Gadepalli RS, Diano S, Cheng Q, Tabrizian T, Gailani D, Rimoldi JM, Shariat-Madar Z. Influence of a novel inhibitor (UM8190) of prolylcarboxypeptidase (PRCP) on appetite and thrombosis. Current Medicinal Chemistry. 19: 4194-206. PMID 22664251 DOI: 10.2174/092986712802430036  0.325
2012 Tucker EI, Verbout NG, Leung PY, Hurst S, McCarty OJ, Gailani D, Gruber A. Inhibition of factor XI activation attenuates inflammation and coagulopathy while improving the survival of mouse polymicrobial sepsis. Blood. 119: 4762-8. PMID 22442348 DOI: 10.1182/Blood-2011-10-386185  0.448
2012 Luo D, Szaba FM, Kummer LW, Johnson LL, Tucker EI, Gruber A, Gailani D, Smiley ST. Factor XI-deficient mice display reduced inflammation, coagulopathy, and bacterial growth during listeriosis. Infection and Immunity. 80: 91-9. PMID 22006565 DOI: 10.1128/Iai.05568-11  0.321
2012 McManus MP, Frantz C, Gailani D. Acquired factor XI deficiency in a child with membranoproliferative glomerulonephritis. Pediatric Blood & Cancer. 59: 173-5. PMID 21850674 DOI: 10.1002/Pbc.23287  0.373
2012 Geng Y, Verhamme IM, Cheng Q, Matafonov A, Smith SB, Sun M, Smith SA, Morrissey JH, Gailani D. The Interaction of Coagulation Factor XI with Polyphosphate Blood. 120: 498-498. DOI: 10.1182/Blood.V120.21.498.498  0.664
2012 Puy C, Wong ZC, Tucker EI, Gruber A, Gailani D, Smith SA, Choi SH, Morrissey JH, McCarty OJ. FXII Promotes Coagulation in a FXI and FIX Independent Manner Blood. 120: 3362-3362. DOI: 10.1182/Blood.V120.21.3362.3362  0.472
2012 Matafonov A, Gailani AE, Grach SL, Leung PY, Cheng Q, Geng Y, McCarty OJ, Tucker EI, Renne T, Morrissey JH, Gruber A, Gailani D. Antibodies to Human Factor XII with Antithrombotic Properties Blood. 120: 1106-1106. DOI: 10.1182/Blood.V120.21.1106.1106  0.662
2011 Gailani D. A cofactor for factor XI activation. Blood. 118: 6730-1. PMID 22194395 DOI: 10.1182/Blood-2011-10-385336  0.492
2011 Revenko AS, Gao D, Crosby JR, Bhattacharjee G, Zhao C, May C, Gailani D, Monia BP, MacLeod AR. Selective depletion of plasma prekallikrein or coagulation factor XII inhibits thrombosis in mice without increased risk of bleeding. Blood. 118: 5302-11. PMID 21821705 DOI: 10.1182/Blood-2011-05-355248  0.447
2011 Itakura A, Verbout NG, Phillips KG, Insall RH, Gailani D, Tucker EI, Gruber A, McCarty OJ. Activated factor XI inhibits chemotaxis of polymorphonuclear leukocytes. Journal of Leukocyte Biology. 90: 923-7. PMID 21807745 DOI: 10.1189/Jlb.0411182  0.378
2011 Müller F, Gailani D, Renné T. Factor XI and XII as antithrombotic targets. Current Opinion in Hematology. 18: 349-55. PMID 21730835 DOI: 10.1097/Moh.0B013E3283497E61  0.422
2011 Luo D, Szaba FM, Kummer LW, Plow EF, Mackman N, Gailani D, Smiley ST. Protective roles for fibrin, tissue factor, plasminogen activator inhibitor-1, and thrombin activatable fibrinolysis inhibitor, but not factor XI, during defense against the gram-negative bacterium Yersinia enterocolitica. Journal of Immunology (Baltimore, Md. : 1950). 187: 1866-76. PMID 21724997 DOI: 10.4049/Jimmunol.1101094  0.413
2011 Matafonov A, Sarilla S, Sun MF, Sheehan JP, Serebrov V, Verhamme IM, Gailani D. Activation of factor XI by products of prothrombin activation. Blood. 118: 437-45. PMID 21527525 DOI: 10.1182/Blood-2010-10-312983  0.408
2011 Mignemi N, Cole H, Yausa M, Gailani D, Degen JL, Schoenecker JG. Deficiency in Plasminogen Cause Decreased Vascularity in Sold Tissue Organs and Bone Blood. 118: 857-857. DOI: 10.1182/Blood.V118.21.857.857  0.302
2011 Crosby JR, Marzec UM, Zhao C, Gao D, Revenko AS, Matafonov A, Gailani D, MacLeod R, Gruber A, Hanson S, Monia BP. Antisense Oligonucleotide Mediated Depletion of Factor XI Prevents Vascular Occlusion in An Experimental Thrombosis Model in Primates Blood. 118: 2250-2250. DOI: 10.1182/Blood.V118.21.2250.2250  0.421
2011 Matafonov A, Cheng Q, Verhamme IM, Umunakwe O, Tucker EI, Sun M, Gruber A, Gailani D. Evidence for a Factor IX-Independent Role for Factor XI in Thrombin Generation Blood. 118: 2244-2244. DOI: 10.1182/Blood.V118.21.2244.2244  0.47
2011 Geng Y, Verhamme IM, Smith SB, Messer AS, Sun M, Bajaj SP, Gailani D. Exosite Interactions in Factor IX Activation by Factor XIa Blood. 118: 2235-2235. DOI: 10.1182/Blood.V118.21.2235.2235  0.627
2011 Tucker EI, Marzec UM, Leung PY, Hanson SR, Verbout NG, Hurst S, McCarty OJ, Gailani D, Gruber A. Apple Domain-Specific Anti-Factor XI Antibodies Inhibit Venous-Type Thrombosis with Improved Hemostatic Safety Profiles Compared to Enoxaparin in Primates Blood. 118: 1173-1173. DOI: 10.1182/Blood.V118.21.1173.1173  0.431
2011 Duvernay MT, Young SE, Gailani D, Schoenecker JG, Hamm H. Coagulation Cofactor Presentation and Complex Assembly on Platelets by Protease Activated Receptors (PARs): PAR4 Stimulation Leads to More FV and FVIII and More Thrombin Generation Than PAR1 Blood. 118: 1135-1135. DOI: 10.1182/Blood.V118.21.1135.1135  0.396
2010 White-Adams TC, Berny MA, Patel IA, Tucker EI, Gailani D, Gruber A, McCarty OJ. Laminin promotes coagulation and thrombus formation in a factor XII-dependent manner. Journal of Thrombosis and Haemostasis : Jth. 8: 1295-301. PMID 20796202 DOI: 10.1111/J.1538-7836.2010.03850.X  0.381
2010 Gailani D, Sun MF, Cheng Q, Matafonov A, Tucker EI, Gruber A, Emsley J. Evidence against a protein in plasma that is a product of a factor XI mRNA splice variant missing exons 6 and 7. Blood. 116: 1185-6; author reply. PMID 20724549 DOI: 10.1182/Blood-2010-01-265702  0.359
2010 Cheng Q, Tucker EI, Pine MS, Sisler I, Matafonov A, Sun MF, White-Adams TC, Smith SA, Hanson SR, McCarty OJ, Renné T, Gruber A, Gailani D. A role for factor XIIa-mediated factor XI activation in thrombus formation in vivo. Blood. 116: 3981-9. PMID 20634381 DOI: 10.1182/Blood-2010-02-270918  0.492
2010 Emsley J, McEwan PA, Gailani D. Structure and function of factor XI. Blood. 115: 2569-77. PMID 20110423 DOI: 10.1182/Blood-2009-09-199182  0.436
2010 Sarilla S, Habib SY, Kravtsov DV, Matafonov A, Gailani D, Verhamme IM. Sucrose octasulfate selectively accelerates thrombin inactivation by heparin cofactor II. The Journal of Biological Chemistry. 285: 8278-89. PMID 20053992 DOI: 10.1074/Jbc.M109.005967  0.331
2010 Gailani D. New Insights Into Factor XI Function: From Biochemistry to Animal Models Blood. 116. DOI: 10.1182/Blood.V116.21.Sci-20.Sci-20  0.509
2010 Tucker EI, Helm M, McCarty OJ, Hurst S, Gailani D, Gruber A. Factor XI Inhibitor Antibody Treatment Improves Survival In a Murine Polymicrobial Sepsis Model Blood. 116: 820-820. DOI: 10.1182/Blood.V116.21.820.820  0.348
2010 Matafonov A, Sarilla S, Sun M, Sheehan JP, Serebrov V, Verhamme I, Gailani D. Activation of Factor XI and the Contact Proteases by Products of Prothrombin Activation. Blood. 116: 1150-1150. DOI: 10.1182/Blood.V116.21.1150.1150  0.48
2009 Gailani D. Factor IX binding to collagen Journal of Thrombosis and Haemostasis. 7: 1840-1842. PMID 19694943 DOI: 10.1111/J.1538-7836.2009.03591.X  0.454
2009 White-Adams TC, Berny MA, Tucker EI, Gertz JM, Gailani D, Urbanus RT, de Groot PG, Gruber A, McCarty OJ. Identification of coagulation factor XI as a ligand for platelet apolipoprotein E receptor 2 (ApoER2). Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 1602-7. PMID 19661487 DOI: 10.1161/Atvbaha.109.187393  0.395
2009 Gailani D, Smith SB. Structural and functional features of factor XI. Journal of Thrombosis and Haemostasis : Jth. 7: 75-8. PMID 19630773 DOI: 10.1111/J.1538-7836.2009.03414.X  0.473
2009 Kravtsov DV, Matafonov A, Tucker EI, Sun MF, Walsh PN, Gruber A, Gailani D. Factor XI contributes to thrombin generation in the absence of factor XII. Blood. 114: 452-8. PMID 19351955 DOI: 10.1182/Blood-2009-02-203604  0.524
2009 Yang L, Sun MF, Gailani D, Rezaie AR. Characterization of a heparin-binding site on the catalytic domain of factor XIa: mechanism of heparin acceleration of factor XIa inhibition by the serpins antithrombin and C1-inhibitor. Biochemistry. 48: 1517-24. PMID 19178150 DOI: 10.1021/Bi802298R  0.382
2009 Tucker EI, Marzec UM, White TC, Hurst S, Rugonyi S, McCarty OJ, Gailani D, Gruber A, Hanson SR. Prevention of vascular graft occlusion and thrombus-associated thrombin generation by inhibition of factor XI. Blood. 113: 936-44. PMID 18945968 DOI: 10.1182/Blood-2008-06-163675  0.413
2009 Spronk HMH, Wilhelm S, Van Oerle R, Knetsch ML, Gailani D, Pawlinski R, Mackman N, Cate Ht, Renné T. Feedback Activation of Factor XI by Thrombin Is Essential for Hemostasis In Vivo. Blood. 114: 2127-2127. DOI: 10.1182/Blood.V114.22.2127.2127  0.509
2008 Smith SB, Gailani D. Update on the physiology and pathology of factor IX activation by factor XIa. Expert Review of Hematology. 1: 87-98. PMID 19714257 DOI: 10.1586/17474086.1.1.87  0.494
2008 Ponczek MB, Gailani D, Doolittle RF. Evolution of the contact phase of vertebrate blood coagulation. Journal of Thrombosis and Haemostasis : Jth. 6: 1876-83. PMID 18761718 DOI: 10.1111/J.1538-7836.2008.03143.X  0.308
2008 Cheng Q, Kantz J, Poffenberger G, Powers AC, Gailani D. Factor XI protein in human pancreas and kidney. Thrombosis and Haemostasis. 100: 158-60. PMID 18612554 DOI: 10.1160/Th08-04-0260  0.367
2008 Tucker EI, Gailani D, Hurst S, Cheng Q, Hanson SR, Gruber A. Survival advantage of coagulation factor XI-deficient mice during peritoneal sepsis. The Journal of Infectious Diseases. 198: 271-4. PMID 18491973 DOI: 10.1086/589514  0.409
2008 Smith SB, Verhamme IM, Sun MF, Bock PE, Gailani D. Characterization of Novel Forms of Coagulation Factor XIa: independence of factor XIa subunits in factor IX activation. The Journal of Biological Chemistry. 283: 6696-705. PMID 18192270 DOI: 10.1074/Jbc.M707234200  0.491
2008 Schmidt AE, Sun MF, Ogawa T, Bajaj SP, Gailani D. Functional role of residue 193 (chymotrypsin numbering) in serine proteases: influence of side chain length and beta-branching on the catalytic activity of blood coagulation factor XIa. Biochemistry. 47: 1326-35. PMID 18186617 DOI: 10.1021/Bi701594J  0.393
2008 White TC, Berny MA, Tucker EI, Pang J, Gailani D, Urbanus RT, de Groot PG, Gruber A, McCarty OJ. Identification of a Role for Apolipoprotein E Receptor 2 as a Platelet Receptor for Factor XI Blood. 112: 3914-3914. DOI: 10.1182/Blood.V112.11.3914.3914  0.393
2008 Gailani D, Smith SB, Agah S, Bajaj SP. An Analysis of Cleavage of the Factor IX Activation Sites by Factor XIa Blood. 112: 3088-3088. DOI: 10.1182/Blood.V112.11.3088.3088  0.476
2008 Schmidt AE, Agah S, Sun M, Padmanabhan K, Cascio D, Gailani D, Bajaj SP. Structural and Functional Significance of Amino Acid Lysine192 (chymotrypsin numbering) in Factor XIa and Factor VIIa. Blood. 112: 2030-2030. DOI: 10.1182/Blood.V112.11.2030.2030  0.366
2008 Yang L, Sun M, Manithody C, Gailani D, Rezaie AR. Characterization of Heparin Binding Site Residues on the Catalytic Domain of Factor XIa Blood. 112: 1018-1018. DOI: 10.1182/blood.v112.11.1018.1018  0.303
2007 Sun MF, Ho D, Martincic D, Ware RE, Walsh PN, Gailani D. Defective binding of factor XI-N248 to activated human platelets. Blood. 110: 4164. PMID 18056845 DOI: 10.1182/Blood.V98.1.125  0.518
2007 Gailani D, Renné T. Intrinsic pathway of coagulation and arterial thrombosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 2507-13. PMID 17916770 DOI: 10.1161/Atvbaha.107.155952  0.469
2007 Anderson PJ, Gailani D, Feys HB, Gao W, Majerus EM, Vanhoorelbeke K, Sadler JE. Factor XI/ADAMTS13 complexes are quantitatively insignificant in human plasma. Haematologica. 92: 1419-22. PMID 17768109 DOI: 10.3324/Haematol.11478  0.352
2007 Renné T, Gailani D. Role of Factor XII in hemostasis and thrombosis: clinical implications. Expert Review of Cardiovascular Therapy. 5: 733-41. PMID 17605651 DOI: 10.1586/14779072.5.4.733  0.474
2007 Gailani D, Renné T. The intrinsic pathway of coagulation: a target for treating thromboembolic disease? Journal of Thrombosis and Haemostasis : Jth. 5: 1106-12. PMID 17388803 DOI: 10.1111/J.1538-7836.2007.02446.X  0.44
2007 Gailani D, Schmidt A, Sun MF, Bolton-Maggs PH, Bajaj SP. A cross-reactive material positive variant of coagulation factor XI (FXIP520L) with a catalytic defect Journal of Thrombosis and Haemostasis. 5: 781-787. PMID 17229051 DOI: 10.1111/J.1538-7836.2007.02390.X  0.443
2006 Wang X, Smith PL, Hsu MY, Gailani D, Schumacher WA, Ogletree ML, Seiffert DA. Effects of factor XI deficiency on ferric chloride-induced vena cava thrombosis in mice. Journal of Thrombosis and Haemostasis : Jth. 4: 1982-8. PMID 16961605 DOI: 10.1111/j.1538-7836.2006.02093.x  0.338
2006 Rezaie AR, Sun MF, Gailani D. Contributions of basic amino acids in the autolysis loop of factor XIa to serpin specificity. Biochemistry. 45: 9427-33. PMID 16878977 DOI: 10.1021/Bi060820+  0.407
2006 Donahue BS, Gailani D, Mast AE. Disposition of tissue factor pathway inhibitor during cardiopulmonary bypass Journal of Thrombosis and Haemostasis. 4: 1011-1016. PMID 16689752 DOI: 10.1111/J.1538-7836.2006.01896.X  0.429
2006 Kleinschnitz C, Stoll G, Bendszus M, Schuh K, Pauer HU, Burfeind P, Renné C, Gailani D, Nieswandt B, Renné T. Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis. The Journal of Experimental Medicine. 203: 513-8. PMID 16533887 DOI: 10.1084/Jem.20052458  0.4
2006 Renné T, Nieswandt B, Gailani D. The intrinsic pathway of coagulation is essential for thrombus stability in mice. Blood Cells, Molecules & Diseases. 36: 148-51. PMID 16466946 DOI: 10.1016/J.Bcmd.2005.12.014  0.464
2006 Smith SB, Sun M, Bock PE, Gailani D. Independence of Factor XIa Subunits in Factor IX Activation. Blood. 108: 334-334. DOI: 10.1182/Blood.V108.11.334.334  0.474
2005 Renné T, Pozgajová M, Grüner S, Schuh K, Pauer HU, Burfeind P, Gailani D, Nieswandt B. Defective thrombus formation in mice lacking coagulation factor XII. The Journal of Experimental Medicine. 202: 271-81. PMID 16009717 DOI: 10.1084/Jem.20050664  0.455
2005 Cheng Q, Zhao Y, Lawson WE, Polosukhin VV, Johnson JE, Blackwell TS, Gailani D. The effects of intrinsic pathway protease deficiencies on plasminogen-deficient mice. Blood. 106: 3055-7. PMID 15985536 DOI: 10.1182/Blood-2005-02-0577  0.359
2005 Ogawa T, Verhamme IM, Sun MF, Bock PE, Gailani D. Exosite-mediated substrate recognition of factor IX by factor XIa. The factor XIa heavy chain is required for initial recognition of factor IX. The Journal of Biological Chemistry. 280: 23523-30. PMID 15829482 DOI: 10.1074/Jbc.M500894200  0.493
2005 Kravtsov DV, Monahan PE, Gailani D. A classification system for cross-reactive material-negative factor XI deficiency. Blood. 105: 4671-3. PMID 15728123 DOI: 10.1182/Blood-2004-05-1864  0.303
2004 Zivelin A, Ogawa T, Bulvik S, Landau M, Toomey JR, Lane J, Seligsohn U, Gailani D. Severe factor XI deficiency caused by a Gly555 to Glu mutation (factor XI-Glu555): A cross-reactive material positive variant defective in factor IX activation Journal of Thrombosis and Haemostasis. 2: 1782-1789. PMID 15456490 DOI: 10.1111/J.1538-7836.2004.00882.X  0.516
2004 Gailani D, Zivelin A, Sinha D, Walsh PN. Do platelets synthesize factor XI? Journal of Thrombosis and Haemostasis. 2: 1709-1712. PMID 15456479 DOI: 10.1111/J.1538-7836.2004.00935.X  0.413
2004 Baglia FA, Gailani D, López JA, Walsh PN. Identification of a binding site for glycoprotein Ibalpha in the Apple 3 domain of factor XI. The Journal of Biological Chemistry. 279: 45470-6. PMID 15317813 DOI: 10.1074/Jbc.M406727200  0.431
2004 Schmidt AE, Ogawa T, Gailani D, Bajaj SP. Structural role of Gly(193) in serine proteases: investigations of a G555E (GLY193 in chymotrypsin) mutant of blood coagulation factor XI. The Journal of Biological Chemistry. 279: 29485-92. PMID 15090552 DOI: 10.1074/Jbc.M402971200  0.422
2004 Kravtsov DV, Wu W, Meijers JC, Sun MF, Blinder MA, Dang TP, Wang H, Gailani D. Dominant factor XI deficiency caused by mutations in the factor XI catalytic domain. Blood. 104: 128-34. PMID 15026311 DOI: 10.1182/Blood-2003-10-3530  0.365
2004 Gailani D, Cheng Q, Xu L, Ogletree M, Wang X. Effect of Factor XI or Factor IX Deficiency on an Arterial Occlusion Model. Blood. 104: 3501-3501. DOI: 10.1182/Blood.V104.11.3501.3501  0.449
2004 Regan Baird T, Gailani D, Furie B, Furie BC. Factor XI Deficient Mice Have Reduced Platelet Accumulation and Fibrin Deposition after Laser Injury. Blood. 104: 218-218. DOI: 10.1182/Blood.V104.11.218.218  0.477
2003 Donahue BS, Byrne DW, Gailani D, George AL. Tissue factor and platelet glycoprotein Ib-alpha alleles are associated with age at first coronary bypass operation. Anesthesiology. 99: 1287-94. PMID 14639140 DOI: 10.1097/00000542-200312000-00009  0.31
2003 Cheng Q, Sun MF, Kravtsov DV, Aktimur A, Gailani D. Factor XI apple domains and protein dimerization Journal of Thrombosis and Haemostasis. 1: 2340-2347. PMID 14629467 DOI: 10.1046/J.1538-7836.2003.00418.X  0.325
2003 Donahue BS, Gailani D, Higgins MS, Drinkwater DC, George AL. Factor V Leiden protects against blood loss and transfusion after cardiac surgery. Circulation. 107: 1003-8. PMID 12600914 DOI: 10.1161/01.Cir.0000051864.28048.01  0.31
2003 Aktimur A, Gabriel MA, Gailani D, Toomey JR. The factor IX gamma-carboxyglutamic acid (Gla) domain is involved in interactions between factor IX and factor XIa. The Journal of Biological Chemistry. 278: 7981-7. PMID 12496253 DOI: 10.1074/Jbc.M212748200  0.497
2003 Gailani D. Factor XI inhibitors Blood. 101: 4649-4649. DOI: 10.1182/Blood-2003-04-1181  0.422
2002 Renné T, Sugiyama A, Gailani D, Jahnen-Dechent W, Walter U, Müller-Esterl W. Fine mapping of the H-kininogen binding site in plasma prekallikrein apple domain 2. International Immunopharmacology. 2: 1867-73. PMID 12489801 DOI: 10.1016/S1567-5769(02)00170-4  0.374
2002 Sinha D, Marcinkiewicz M, Gailani D, Walsh PN. Molecular cloning and biochemical characterization of rabbit factor XI. The Biochemical Journal. 367: 49-56. PMID 12084014 DOI: 10.1042/Bj20020232  0.468
2002 Renné T, Gailani D, Meijers JC, Müller-Esterl W. Characterization of the H-kininogen-binding site on factor XI: a comparison of factor XI and plasma prekallikrein. The Journal of Biological Chemistry. 277: 4892-9. PMID 11733491 DOI: 10.1074/Jbc.M105221200  0.35
2001 Gailani D, Ho D, Sun MF, Cheng Q, Walsh PN. Model for a factor IX activation complex on blood platelets: Dimeric conformation of factor XIa is essential Blood. 97: 3117-3122. PMID 11342438 DOI: 10.1182/Blood.V97.10.3117  0.53
2001 Gailani D. Gene targeting in hemostasis. factor XI Frontiers in Bioscience : a Journal and Virtual Library. 6. PMID 11171549 DOI: 10.2741/Gailani  0.466
2001 Chan JC, Ganopolsky JG, Cornelissen I, Suckow MA, Sandoval-Cooper MJ, Brown EC, Noria F, Gailani D, Rosen ED, Ploplis VA, Castellino FJ. The characterization of mice with a targeted combined deficiency of protein c and factor XI. The American Journal of Pathology. 158: 469-79. PMID 11159184 DOI: 10.1016/S0002-9440(10)63989-2  0.322
2000 Gailani D. Activation of factor IX by factor XIa Trends in Cardiovascular Medicine. 10: 198-204. PMID 11282295 DOI: 10.1016/S1050-1738(00)00070-0  0.497
2000 Ho DH, Badellino K, Baglia FA, Sun MF, Zhao MM, Gailani D, Walsh PN. The role of high molecular weight kininogen and prothrombin as cofactors in the binding of factor XI A3 domain to the platelet surface. The Journal of Biological Chemistry. 275: 25139-45. PMID 10823824 DOI: 10.1074/Jbc.M001890200  0.45
2000 Barrow RT, Healey JF, Gailani D, Scandella D, Lollar P. Reduction of the antigenicity of factor VIII toward complex inhibitory antibody plasmas using multiply-substituted hybrid human/porcine factor VIII molecules Blood. 95: 564-568. PMID 10627463 DOI: 10.1182/Blood.V95.2.564  0.377
1999 Sun MF, Zhao M, Gailani D. Identification of amino acids in the factor XI apple 3 domain required for activation of factor IX Journal of Biological Chemistry. 274: 36373-36378. PMID 10593931 DOI: 10.1074/Jbc.274.51.36373  0.48
1999 Martincic D, Kravtsov V, Gailani D. Factor XI messenger RNA in human platelets Blood. 94: 3397-3404. PMID 10552949 DOI: 10.1182/Blood.V94.10.3397.422K21_3397_3404  0.361
1999 Gailani D, Reese EP. Anticoagulant-induced skin necrosis in a patient with hereditary deficiency of protein S. American Journal of Hematology. 60: 231-6. PMID 10072117 DOI: 10.1002/(Sici)1096-8652(199903)60:3<231::Aid-Ajh12>3.0.Co;2-N  0.361
1998 Zhao M, Abdel-Razek T, Sun MF, Gailani D. Characterization of a heparin binding site on the heavy chain of factor XI Journal of Biological Chemistry. 273: 31153-31159. PMID 9813019 DOI: 10.1074/Jbc.273.47.31153  0.418
1998 Martincic D, Zimmerman SA, Ware RE, Sun MF, Whitlock JA, Gailani D. Identification of mutations and polymorphisms in the factor XI genes of an African American family by dideoxyfingerprinting Blood. 92: 3309-3317. PMID 9787168 DOI: 10.1182/Blood.V92.9.3309.421K36_3309_3317  0.376
1997 Gailani D, Lasky NM, Broze GJ. A murine model of factor XI deficiency Blood Coagulation and Fibrinolysis. 8: 134-144. PMID 9518045 DOI: 10.1097/00001721-199703000-00008  0.454
1997 Gailani D, Sun MF, Sun Y. A comparison of murine and human factor XI Blood. 90: 1055-1064. PMID 9242536 DOI: 10.1182/Blood.V90.3.1055.1055_1055_1064  0.468
1996 Sun Y, Gailani D. Identification of a factor IX binding site on the third apple domain of activated factor XI Journal of Biological Chemistry. 271: 29023-29028. PMID 8910554 DOI: 10.1074/Jbc.271.46.29023  0.502
1994 Gailani D. Advances and dilemmas in factor XI Current Opinion in Hematology. 1: 347-353. PMID 9371304  0.395
1994 Girard TJ, Gailani D, Broze GJ. Complementary DNA sequencing of canine tissue factor pathway inhibitor reveals a unique nanomeric repetitive sequence between the second and third Kunitz domains Biochemical Journal. 303: 923-928. PMID 7980463 DOI: 10.1042/Bj3030923  0.35
1993 Gailani D, Broze GJ. Effects of glycosaminoglycans on factor XI activation by thrombin Blood Coagulation and Fibrinolysis. 4: 15-20. PMID 8457645 DOI: 10.1097/00001721-199304010-00003  0.489
1993 Gailani D, Broze GJ. Factor XII-independent activation of factor XI in plasma: Effects of sulfatides on tissue factor-induced coagulation Blood. 82: 813-819. PMID 8338946 DOI: 10.1182/Blood.V82.3.813.813  0.471
1993 Broze GJ, Gailani D. The role of factor XI in coagulation Thrombosis and Haemostasis. 70: 72-74. PMID 8236118 DOI: 10.1055/S-0038-1646163  0.413
1993 Gailani D, Broze GJ. Factor XI activation by thrombin and Factor XIa Seminars in Thrombosis and Hemostasis. 19: 396-404. PMID 8140432 DOI: 10.1055/S-2007-993291  0.496
1992 Gailani D. An IgG inhibitor against coagulation factor XIII: Resolution of bleeding after plasma immunoadsorption with staphylococcal protein A The American Journal of Medicine. 92: 110-112. PMID 1731502 DOI: 10.1016/0002-9343(92)90028-A  0.412
1991 Gailani D, Broze GJ. Factor XI activation in a revised model of blood coagulation Science. 253: 909-912. PMID 1652157 DOI: 10.1126/Science.1652157  0.477
1990 Gailani D, Fisher TC, Mills DCB, Macfarlane DE. P47 phosphoprotein of blood platelets (pleckstrin) is a major target for phorbol ester-induced protein phosphorylation in intact platelets, granulocytes, lymphocytes, monocytes and cultured leukaemic cells: Absence of P47 in non-haematopoietic cells British Journal of Haematology. 74: 192-202. PMID 2317454 DOI: 10.1111/J.1365-2141.1990.Tb02565.X  0.309
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