Andrew D. McCulloch - Publications

Affiliations: 
Bioengineering University of California, San Diego, La Jolla, CA 
Area:
computational Biology, cardiac

224 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Saucerman JJ, Tan PM, Buchholz KS, McCulloch AD, Omens JH. Mechanical regulation of gene expression in cardiac myocytes and fibroblasts. Nature Reviews. Cardiology. PMID 30683889 DOI: 10.1038/s41569-019-0155-8  1
2018 Lewalle A, Land S, Carruth E, Frank LR, Lamata P, Omens JH, McCulloch AD, Niederer SA, Smith NP. Decreasing Compensatory Ability of Concentric Ventricular Hypertrophy in Aortic-Banded Rat Hearts. Frontiers in Physiology. 9: 37. PMID 29527171 DOI: 10.3389/fphys.2018.00037  0.72
2018 Gilbert K, Forsch N, Hegde S, Mauger C, Omens JH, Perry JC, Pontré B, Suinesiaputra A, Young AA, McCulloch AD. Atlas-Based Computational Analysis of Heart Shape and Function in Congenital Heart Disease. Journal of Cardiovascular Translational Research. PMID 29294215 DOI: 10.1007/s12265-017-9778-5  0.72
2017 Erdemir A, Hunter PJ, Holzapfel GA, Loew LM, Middleton J, Jacobs CR, Nithiarasu P, Lohner R, Wei G, Winkelstein BA, Barocas VH, Guilak F, Ku J, Hicks JL, Delp S, ... ... McCulloch AD, et al. Perspectives on Sharing Models and Related Resources in Computational Biomechanics Research. Journal of Biomechanical Engineering. PMID 29247253 DOI: 10.1115/1.4038768  0.68
2017 Tan PM, Buchholz KS, Omens JH, McCulloch AD, Saucerman JJ. Predictive model identifies key network regulators of cardiomyocyte mechano-signaling. Plos Computational Biology. 13: e1005854. PMID 29131824 DOI: 10.1371/journal.pcbi.1005854  1
2017 Timmermann V, Dejgaard LA, Haugaa KH, Edwards AG, Sundnes J, McCulloch AD, Wall ST. An integrative appraisal of mechano-electric feedback mechanisms in the heart. Progress in Biophysics and Molecular Biology. PMID 28851517 DOI: 10.1016/j.pbiomolbio.2017.08.008  0.68
2017 Gan Z, Powell FL, Zambon AC, Buchholz KS, Fu Z, Ocorr K, Bodmer R, Moya EA, Stowe JC, Haddad GG, McCulloch AD. Transcriptomic analysis identifies a role of PI3K/Akt signalling in the responses of skeletal muscle to acute hypoxia in vivo. The Journal of Physiology. PMID 28688178 DOI: 10.1113/JP274556  0.48
2017 Dewan S, Krishnamurthy A, Kole D, Conca G, Kerckhoffs R, Puchalski MD, Omens JH, Sun H, Nigam V, McCulloch AD. Model of Human Fetal Growth in Hypoplastic Left Heart Syndrome: Reduced Ventricular Growth Due to Decreased Ventricular Filling and Altered Shape. Frontiers in Pediatrics. 5: 25. PMID 28275592 DOI: 10.3389/fped.2017.00025  0.72
2016 Farrar G, Suinesiaputra A, Gilbert K, Perry JC, Hegde S, Marsden A, Young AA, Omens JH, McCulloch AD. Atlas-Based Ventricular Shape Analysis for Understanding Congenital Heart Disease. Progress in Pediatric Cardiology. 43: 61-69. PMID 28082823 DOI: 10.1016/j.ppedcard.2016.07.010  0.72
2016 Villongco CT, Krummen DE, Omens JH, McCulloch AD. Non-invasive, model-based measures of ventricular electrical dyssynchrony for predicting CRT outcomes. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. 18: iv104-iv112. PMID 28011837 DOI: 10.1093/europace/euw356  0.72
2016 Carruth ED, McCulloch AD, Omens JH. Transmural gradients of myocardial structure and mechanics: Implications for fiber stress and strain in pressure overload. Progress in Biophysics and Molecular Biology. PMID 27845176 DOI: 10.1016/j.pbiomolbio.2016.11.004  0.72
2016 Yang PC, Boras BW, Jeng MT, Docken SS, Lewis TJ, McCulloch AD, Harvey RD, Clancy CE. A Computational Modeling and Simulation Approach to Investigate Mechanisms of Subcellular cAMP Compartmentation. Plos Computational Biology. 12: e1005005. PMID 27409243 DOI: 10.1371/journal.pcbi.1005005  1
2016 Suinesiaputra A, McCulloch AD, Nash MP, Pontre B, Young AA. Cardiac image modelling: Breadth and depth in heart disease. Medical Image Analysis. PMID 27349830 DOI: 10.1016/j.media.2016.06.027  0.6
2016 Zhang Y, Barocas VH, Berceli SA, Clancy CE, Eckmann DM, Garbey M, Kassab GS, Lochner DR, McCulloch AD, Tran-Son-Tay R, Trayanova NA. Multi-scale Modeling of the Cardiovascular System: Disease Development, Progression, and Clinical Intervention. Annals of Biomedical Engineering. PMID 27138523 DOI: 10.1007/s10439-016-1628-0  0.6
2016 Mezzano V, Liang Y, Wright AT, Lyon RC, Pfeiffer E, Song MY, Gu Y, Dalton ND, Scheinman M, Peterson KL, Evans SM, Fowler S, Cerrone M, McCulloch AD, Sheikh F. Desmosomal Junctions Are Necessary for Adult Sinus Node Function. Cardiovascular Research. PMID 27097650 DOI: 10.1093/cvr/cvw083  1
2015 Boras BW, Hirakis SP, Votapka LW, Malmstrom RD, Amaro RE, McCulloch AD. Bridging scales through multiscale modeling: a case study on protein kinase A. Frontiers in Physiology. 6: 250. PMID 26441670 DOI: 10.3389/fphys.2015.00250  1
2015 Vincent KP, Gonzales MJ, Gillette AK, Villongco CT, Pezzuto S, Omens JH, Holst MJ, McCulloch AD. High-order finite element methods for cardiac monodomain simulations. Frontiers in Physiology. 6: 217. PMID 26300783 DOI: 10.3389/fphys.2015.00217  1
2015 Suarez SL, Rane AA, Muñoz A, Wright AT, Zhang SX, Braden RL, Almutairi A, McCulloch AD, Christman KL. Intramyocardial injection of hydrogel with high interstitial spread does not impact action potential propagation. Acta Biomaterialia. PMID 26265060 DOI: 10.1016/j.actbio.2015.08.004  0.6
2015 Morotti S, McCulloch AD, Bers DM, Edwards AG, Grandi E. Atrial-selective targeting of arrhythmogenic phase-3 early afterdepolarizations in human myocytes. Journal of Molecular and Cellular Cardiology. PMID 26241847 DOI: 10.1016/j.yjmcc.2015.07.030  0.68
2015 Guimarães-Camboa N, Stowe J, Aneas I, Sakabe N, Cattaneo P, Henderson L, Kilberg MS, Johnson RS, Chen J, McCulloch AD, Nobrega MA, Evans SM, Zambon AC. HIF1α Represses Cell Stress Pathways to Allow Proliferation of Hypoxic Fetal Cardiomyocytes. Developmental Cell. 33: 507-21. PMID 26028220 DOI: 10.1016/j.devcel.2015.04.021  0.6
2015 Henney A, Hunter P, McCulloch A, Noble D. Multi-bio and multi-scale systems biology. Progress in Biophysics and Molecular Biology. 117: 1-3. PMID 25783046 DOI: 10.1016/j.pbiomolbio.2015.03.001  1
2015 Krishnamurthy A, Villongco C, Beck A, Omens J, McCulloch A. Left Ventricular Diastolic and Systolic Material Property Estimation from Image Data: LV Mechanics Challenge. Statistical Atlases and Computational Models of the Heart : Imaging and Modelling Challenges : 5th International Workshop, Stacom 2014, Held in Conjunction With Miccai 2014, Boston, Ma, Usa, September 18, 2014, Revised Selected Papers /.... 8896: 63-73. PMID 25729778 DOI: 10.1007/978-3-319-14678-2_7  1
2015 Stobdan T, Zhou D, Ao-Ieong E, Ortiz D, Ronen R, Hartley I, Gan Z, McCulloch AD, Bafna V, Cabrales P, Haddad GG. Endothelin receptor B, a candidate gene from human studies at high altitude, improves cardiac tolerance to hypoxia in genetically engineered heterozygote mice Proceedings of the National Academy of Sciences of the United States of America. 112: 10425-10430. DOI: 10.1073/pnas.1507486112  0.6
2015 Morotti S, McCulloch AD, Bers DM, Edwards AG, Grandi E. Atrial-selective targeting of arrhythmogenic phase-3 early afterdepolarizations in human myocytes Journal of Molecular and Cellular Cardiology. DOI: 10.1016/j.yjmcc.2015.07.030  0.6
2015 de Oliveira BL, Pfeiffer ER, Sundnes J, Wall ST, McCulloch AD. Increased Cell Membrane Capacitance is the Dominant Mechanism of Stretch-Dependent Conduction Slowing in the Rabbit Heart: A Computational Study Cellular and Molecular Bioengineering. 8: 237-246. DOI: 10.1007/s12195-015-0384-9  1
2014 Gonzales MJ, Vincent KP, Rappel WJ, Narayan SM, McCulloch AD. Structural contributions to fibrillatory rotors in a patient-derived computational model of the atria. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. 16: iv3-iv10. PMID 25362167 DOI: 10.1093/europace/euu251  0.6
2014 Pfeiffer ER, Wright AT, Edwards AG, Stowe JC, McNall K, Tan J, Niesman I, Patel HH, Roth DM, Omens JH, McCulloch AD. Caveolae in ventricular myocytes are required for stretch-dependent conduction slowing. Journal of Molecular and Cellular Cardiology. 76: 265-74. PMID 25257915 DOI: 10.1016/j.yjmcc.2014.09.014  1
2014 Edwards AG, Grandi E, Hake JE, Patel S, Li P, Miyamoto S, Omens JH, Heller Brown J, Bers DM, McCulloch AD. Nonequilibrium reactivation of Na+ current drives early afterdepolarizations in mouse ventricle. Circulation. Arrhythmia and Electrophysiology. 7: 1205-13. PMID 25236710 DOI: 10.1161/CIRCEP.113.001666  1
2014 Boras BW, Kornev A, Taylor SS, McCulloch AD. Using Markov state models to develop a mechanistic understanding of protein kinase A regulatory subunit RIα activation in response to cAMP binding. The Journal of Biological Chemistry. 289: 30040-51. PMID 25202018 DOI: 10.1074/jbc.M114.568907  1
2014 Villongco CT, Krummen DE, Stark P, Omens JH, McCulloch AD. Patient-specific modeling of ventricular activation pattern using surface ECG-derived vectorcardiogram in bundle branch block. Progress in Biophysics and Molecular Biology. 115: 305-13. PMID 25110279 DOI: 10.1016/j.pbiomolbio.2014.06.011  1
2014 Vincent KP, McCulloch AD, Edwards AG. Toward a hierarchy of mechanisms in CaMKII-mediated arrhythmia. Frontiers in Pharmacology. 5: 110. PMID 24994983 DOI: 10.3389/fphar.2014.00110  1
2014 Tangney JR, Campbell SG, McCulloch AD, Omens JH. Timing and magnitude of systolic stretch affect myofilament activation and mechanical work. American Journal of Physiology. Heart and Circulatory Physiology. 307: H353-60. PMID 24878774 DOI: 10.1152/ajpheart.00233.2014  1
2014 Hohendanner F, McCulloch AD, Blatter LA, Michailova AP. Calcium and IP3 dynamics in cardiac myocytes: experimental and computational perspectives and approaches. Frontiers in Pharmacology. 5: 35. PMID 24639654 DOI: 10.3389/fphar.2014.00035  1
2014 Gan Z, Wang J, Salomonis N, Stowe JC, Haddad GG, McCulloch AD, Altintas I, Zambon AC. MAAMD: a workflow to standardize meta-analyses and comparison of affymetrix microarray data. Bmc Bioinformatics. 15: 69. PMID 24621103 DOI: 10.1186/1471-2105-15-69  1
2014 Banerjee I, Zhang J, Moore-Morris T, Pfeiffer E, Buchholz KS, Liu A, Ouyang K, Stroud MJ, Gerace L, Evans SM, McCulloch A, Chen J. Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response. Plos Genetics. 10: e1004114. PMID 24586179 DOI: 10.1371/journal.pgen.1004114  1
2014 Hake J, Kekenes-Huskey PM, McCulloch AD. Computational modeling of subcellular transport and signaling. Current Opinion in Structural Biology. 25: 92-7. PMID 24509246 DOI: 10.1016/j.sbi.2014.01.006  1
2014 Morotti S, Edwards AG, McCulloch AD, Bers DM, Grandi E. A novel computational model of mouse myocyte electrophysiology to assess the synergy between Na+ loading and CaMKII. The Journal of Physiology. 592: 1181-97. PMID 24421356 DOI: 10.1113/jphysiol.2013.266676  1
2014 Pfeiffer ER, Tangney JR, Omens JH, McCulloch AD. Biomechanics of cardiac electromechanical coupling and mechanoelectric feedback. Journal of Biomechanical Engineering. 136: 021007. PMID 24337452 DOI: 10.1115/1.4026221  1
2014 Lyon RC, Mezzano V, Wright AT, Pfeiffer E, Chuang J, Banares K, Castaneda A, Ouyang K, Cui L, Contu R, Gu Y, Evans SM, Omens JH, Peterson KL, McCulloch AD, et al. Connexin defects underlie arrhythmogenic right ventricular cardiomyopathy in a novel mouse model. Human Molecular Genetics. 23: 1134-50. PMID 24108106 DOI: 10.1093/hmg/ddt508  1
2014 Sundnes J, Wall S, Osnes H, Thorvaldsen T, McCulloch AD. Improved discretisation and linearisation of active tension in strongly coupled cardiac electro-mechanics simulations. Computer Methods in Biomechanics and Biomedical Engineering. 17: 604-15. PMID 22800534 DOI: 10.1080/10255842.2012.704368  1
2014 Gan Z, Stowe JC, Altintas I, Mcculloch AD, Zambon AC. Using kepler for tool integration in microarray analysis workflows Procedia Computer Science. 29: 2162-2167. DOI: 10.1016/j.procs.2014.05.201  1
2013 Liao T, Zhang Y, Kekenes-Huskey PM, Cheng Y, Michailova A, McCulloch AD, Holst M, McCammon JA. Multi-core CPU or GPU-accelerated Multiscale Modeling for Biomolecular Complexes. Molecular Based Mathematical Biology (Online). 1. PMID 24352481 DOI: 10.2478/mlbmb-2013-0009  0.4
2013 Lo YH, Peachey T, Abramson D, McCulloch A, Michailova A. Sensitivity of rabbit ventricular action potential and Ca2+ dynamics to small variations in membrane currents and ion diffusion coefficients Biomed Research International. 2013. PMID 24222910 DOI: 10.1155/2013/565431  1
2013 Kekenes-Huskey PM, Liao T, Gillette AK, Hake JE, Zhang Y, Michailova AP, McCulloch AD, McCammon JA. Molecular and subcellular-scale modeling of nucleotide diffusion in the cardiac myofilament lattice. Biophysical Journal. 105: 2130-40. PMID 24209858 DOI: 10.1016/j.bpj.2013.09.020  0.56
2013 Westenbrink BD, Edwards AG, McCulloch AD, Brown JH. The promise of CaMKII inhibition for heart disease: preventing heart failure and arrhythmias. Expert Opinion On Therapeutic Targets. 17: 889-903. PMID 23789646 DOI: 10.1517/14728222.2013.809064  1
2013 Krishnamurthy A, Villongco CT, Chuang J, Frank LR, Nigam V, Belezzuoli E, Stark P, Krummen DE, Narayan S, Omens JH, McCulloch AD, Kerckhoffs RC. Patient-Specific Models of Cardiac Biomechanics. Journal of Computational Physics. 244: 4-21. PMID 23729839 DOI: 10.1016/j.jcp.2012.09.015  1
2013 Howard EJ, Kerckhoffs RC, Vincent KP, Krishnamurthy A, Villongco CT, Mulligan LJ, McCulloch AD, Omens JH. Myofiber prestretch magnitude determines regional systolic function during ectopic activation in the tachycardia-induced failing canine heart. American Journal of Physiology. Heart and Circulatory Physiology. 305: H192-202. PMID 23666676 DOI: 10.1152/ajpheart.00186.2012  1
2013 Gonzales MJ, Sturgeon G, Krishnamurthy A, Hake J, Jonas R, Stark P, Rappel WJ, Narayan SM, Zhang Y, Segars WP, McCulloch AD. A three-dimensional finite element model of human atrial anatomy: new methods for cubic Hermite meshes with extraordinary vertices. Medical Image Analysis. 17: 525-37. PMID 23602918 DOI: 10.1016/j.media.2013.03.005  1
2013 Tang T, Lai NC, Wright AT, Gao MH, Lee P, Guo T, Tang R, McCulloch AD, Hammond HK. Adenylyl cyclase 6 deletion increases mortality during sustained β-adrenergic receptor stimulation. Journal of Molecular and Cellular Cardiology. 60: 60-7. PMID 23587598 DOI: 10.1016/j.yjmcc.2013.04.005  1
2013 Tangney JR, Chuang JS, Janssen MS, Krishnamurthy A, Liao P, Hoshijima M, Wu X, Meininger GA, Muthuchamy M, Zemljic-Harpf A, Ross RS, Frank LR, McCulloch AD, Omens JH. Novel role for vinculin in ventricular myocyte mechanics and dysfunction. Biophysical Journal. 104: 1623-33. PMID 23561539 DOI: 10.1016/j.bpj.2013.02.021  1
2013 Michailova AP, Edwards AG, Hake J, Hoshijima M, McCulloch AD. Calcium Signaling in Cardiomyocyte Models With Realistic Geometries Cardiac Electrophysiology: From Cell to Bedside: Sixth Edition. 331-340. DOI: 10.1016/B978-1-4557-2856-5.00033-9  0.6
2012 Meng P, Irturk A, Kastner R, McCulloch A, Omens J, Wright A. GPU acceleration of optical mapping algorithm for cardiac electrophysiology. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2012: 1558-61. PMID 23366201 DOI: 10.1109/EMBC.2012.6346240  1
2012 Kerckhoffs RC, Omens JH, McCulloch AD. Mechanical discoordination increases continuously after the onset of left bundle branch block despite constant electrical dyssynchrony in a computational model of cardiac electromechanics and growth. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. 14: v65-v72. PMID 23104917 DOI: 10.1093/europace/eus274  1
2012 Kekenes-Huskey PM, Cheng Y, Hake JE, Sachse FB, Bridge JH, Holst MJ, McCammon JA, McCulloch AD, Michailova AP. Modeling effects of L-type ca(2+) current and na(+)-ca(2+) exchanger on ca(2+) trigger flux in rabbit myocytes with realistic T-tubule geometries. Frontiers in Physiology. 3: 351. PMID 23060801 DOI: 10.3389/fphys.2012.00351  0.56
2012 Smith NP, McCulloch AD, Paterson DJ. What can modelling provide to cardiac physiology? The Journal of Physiology. 590: 4401-2. PMID 22988258 DOI: 10.1113/jphysiol.2012.242578  1
2012 Zhang Y, Liang X, Ma J, Jing Y, Gonzales MJ, Villongco C, Krishnamurthy A, Frank LR, Nigam V, Stark P, Narayan SM, McCulloch AD. An atlas-based geometry pipeline for cardiac Hermite model construction and diffusion tensor reorientation. Medical Image Analysis. 16: 1130-41. PMID 22841777 DOI: 10.1016/j.media.2012.06.005  1
2012 Tveito A, Lines GT, Edwards AG, Maleckar MM, Michailova A, Hake J, McCulloch A. Slow Calcium-Depolarization-Calcium waves may initiate fast local depolarization waves in ventricular tissue Progress in Biophysics and Molecular Biology. 110: 295-304. PMID 22841534 DOI: 10.1016/j.pbiomolbio.2012.07.005  1
2012 Raskin A, Lange S, Banares K, Lyon RC, Zieseniss A, Lee LK, Yamazaki KG, Granzier HL, Gregorio CC, McCulloch AD, Omens JH, Sheikh F. A novel mechanism involving four-and-a-half LIM domain protein-1 and extracellular signal-regulated kinase-2 regulates titin phosphorylation and mechanics. The Journal of Biological Chemistry. 287: 29273-84. PMID 22778266 DOI: 10.1074/jbc.M112.372839  1
2012 Kerckhoffs RC, Omens J, McCulloch AD. A single strain-based growth law predicts concentric and eccentric cardiac growth during pressure and volume overload. Mechanics Research Communications. 42: 40-50. PMID 22639476 DOI: 10.1016/j.mechrescom.2011.11.004  1
2012 Hake J, Edwards AG, Yu Z, Kekenes-Huskey PM, Michailova AP, McCammon JA, Holst MJ, Hoshijima M, McCulloch AD. Modelling cardiac calcium sparks in a three-dimensional reconstruction of a calcium release unit. The Journal of Physiology. 590: 4403-22. PMID 22495592 DOI: 10.1113/jphysiol.2012.227926  0.68
2012 Sheikh F, Ouyang K, Campbell SG, Lyon RC, Chuang J, Fitzsimons D, Tangney J, Hidalgo CG, Chung CS, Cheng H, Dalton ND, Gu Y, Kasahara H, Ghassemian M, Omens JH, ... ... McCulloch AD, et al. Mouse and computational models link Mlc2v dephosphorylation to altered myosin kinetics in early cardiac disease. The Journal of Clinical Investigation. 122: 1209-21. PMID 22426213 DOI: 10.1172/JCI61134  1
2012 Feala JD, Cortes J, Duxbury PM, McCulloch AD, Piermarocchi C, Paternostro G. Statistical properties and robustness of biological controller-target networks. Plos One. 7: e29374. PMID 22235289 DOI: 10.1371/journal.pone.0029374  1
2012 Hunt DL, Campbell PH, Zambon AC, Vranizan K, Evans SM, Kuo HC, Yamaguchi KD, Omens JH, McCulloch AD. Early postmyocardial infarction survival in Murphy Roths Large mice is mediated by attenuated apoptosis and inflammation but depends on genetic background. Experimental Physiology. 97: 102-14. PMID 21967898 DOI: 10.1113/expphysiol.2011.060269  1
2012 Gan Z, Wang J, Salomonis N, Altintas I, McCulloch AD, Zambon A. MAAMD: A workflow to standardize meta-analyses of affymetrix microarray data Proceedings - 2012 Ieee 2nd Conference On Healthcare Informatics, Imaging and Systems Biology, Hisb 2012. 120. DOI: 10.1109/HISB.2012.45  1
2012 McCulloch AD. Multiscale modeling and imaging of the failing heart: From mouse to human Computational Biomechanics For Medicine: Deformation and Flow. 3. DOI: 10.1007/978-1-4614-3172-5_1  1
2012 Sheikh F, Raskin A, Chu PH, Lange S, Domenighetti AA, Zheng M, Liang X, Zhang T, Yajima T, Gu Y, Dalton ND, Mahata SK, Dorn GW, Brown JH, Peterson KL, ... ... McCulloch AD, et al. An FHL1-containing complex within the cardiomyocyte sarcomere mediates hypertrophic biomechanical stress responses in mice (Journal of Clinical Investigation (2008) 118, 12, (3870-3880) doi:10.1172/JCI34472) Journal of Clinical Investigation. 122: 1584.  1
2011 Meyer GA, McCulloch AD, Lieber RL. A nonlinear model of passive muscle viscosity. Journal of Biomechanical Engineering. 133: 091007. PMID 22010742 DOI: 10.1115/1.4004993  1
2011 Viceconti M, McCulloch AD. Policy needs and options for a common approach towards modelling and simulation of human physiology and diseases with a focus on the virtual physiological human. Studies in Health Technology and Informatics. 170: 49-82. PMID 21893899 DOI: 10.3233/978-1-60750-810-6-49  1
2011 Campbell SG, McCulloch AD. Multi-scale computational models of familial hypertrophic cardiomyopathy: genotype to phenotype. Journal of the Royal Society, Interface / the Royal Society. 8: 1550-61. PMID 21831889 DOI: 10.1098/rsif.2011.0184  1
2011 Howard EJ, Covell JW, Mulligan LJ, McCulloch AD, Omens JH, Kerckhoffs RC. Improvement in pump function with endocardial biventricular pacing increases with activation time at the left ventricular pacing site in failing canine hearts. American Journal of Physiology. Heart and Circulatory Physiology. 301: H1447-55. PMID 21784986 DOI: 10.1152/ajpheart.00295.2011  1
2011 Aguado-Sierra J, Krishnamurthy A, Villongco C, Chuang J, Howard E, Gonzales MJ, Omens J, Krummen DE, Narayan S, Kerckhoffs RC, McCulloch AD. Patient-specific modeling of dyssynchronous heart failure: a case study. Progress in Biophysics and Molecular Biology. 107: 147-55. PMID 21763714 DOI: 10.1016/j.pbiomolbio.2011.06.014  1
2011 Quinn TA, Granite S, Allessie MA, Antzelevitch C, Bollensdorff C, Bub G, Burton RA, Cerbai E, Chen PS, Delmar M, Difrancesco D, Earm YE, Efimov IR, Egger M, Entcheva E, ... ... McCulloch AD, et al. Minimum Information about a Cardiac Electrophysiology Experiment (MICEE): standardised reporting for model reproducibility, interoperability, and data sharing. Progress in Biophysics and Molecular Biology. 107: 4-10. PMID 21745496 DOI: 10.1016/j.pbiomolbio.2011.07.001  1
2011 Tveito A, Lines GT, Li P, McCulloch A. Defining candidate drug characteristics for long-QT (LQT3) syndrome Mathematical Biosciences and Engineering. 8: 861-873. PMID 21675815 DOI: 10.3934/mbe.2011.8.861  1
2010 Cheng Y, Yu Z, Hoshijima M, Holst MJ, McCulloch AD, McCammon JA, Michailova AP. Numerical analysis of Ca2+ signaling in rat ventricular myocytes with realistic transverse-axial tubular geometry and inhibited sarcoplasmic reticulum. Plos Computational Biology. 6: e1000972. PMID 21060856 DOI: 10.1371/journal.pcbi.1000972  1
2010 Chuang JS, Zemljic-Harpf A, Ross RS, Frank LR, McCulloch AD, Omens JH. Determination of three-dimensional ventricular strain distributions in gene-targeted mice using tagged MRI. Magnetic Resonance in Medicine. 64: 1281-8. PMID 20981782 DOI: 10.1002/mrm.22547  1
2010 Feala JD, Cortes J, Duxbury PM, Piermarocchi C, McCulloch AD, Paternostro G. Systems approaches and algorithms for discovery of combinatorial therapies. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 2: 181-93. PMID 20836021 DOI: 10.1002/wsbm.51  1
2010 Campbell SG, Lionetti FV, Campbell KS, McCulloch AD. Coupling of adjacent tropomyosins enhances cross-bridge-mediated cooperative activation in a markov model of the cardiac thin filament. Biophysical Journal. 98: 2254-64. PMID 20483334 DOI: 10.1016/j.bpj.2010.02.010  1
2010 Kerckhoffs RC, Omens JH, McCulloch AD, Mulligan LJ. Ventricular dilation and electrical dyssynchrony synergistically increase regional mechanical nonuniformity but not mechanical dyssynchrony: a computational model. Circulation. Heart Failure. 3: 528-36. PMID 20466849 DOI: 10.1161/CIRCHEARTFAILURE.109.862144  1
2010 Jacot JG, Kita-Matsuo H, Wei KA, Chen HS, Omens JH, Mercola M, McCulloch AD. Cardiac myocyte force development during differentiation and maturation. Annals of the New York Academy of Sciences. 1188: 121-7. PMID 20201894 DOI: 10.1111/j.1749-6632.2009.05091.x  1
2010 Lionetti FV, McCulloch AD, Baden SB. Source-to-source optimization of CUDA C for GPU accelerated cardiac cell modeling Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 6271: 38-49. DOI: 10.1007/978-3-642-15277-1_5  1
2010 Aguado-Sierra J, Kerckhoffs RCP, Lionetti F, Hunt D, Villongco C, Gonzales M, Campbell SG, McCulloch AD. A computational framework for patient-specific multi-scale cardiac modeling Patient-Specific Modeling of the Cardiovascular System: Technology-Driven Personalized Medicine. 203-223. DOI: 10.1007/978-1-4419-6691-9_12  1
2009 Kerckhoffs RC, Campbell SG, Flaim SN, Howard EJ, Sierra-Aguado J, Mulligan LJ, McCulloch AD. Multi-scale modeling of excitation-contraction coupling in the normal and failing heart. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2009: 4281-2. PMID 19963818 DOI: 10.1109/IEMBS.2009.5332708  1
2009 Feala JD, Coquin L, Zhou D, Haddad GG, Paternostro G, McCulloch AD. Metabolism as means for hypoxia adaptation: metabolic profiling and flux balance analysis. Bmc Systems Biology. 3: 91. PMID 19740440 DOI: 10.1186/1752-0509-3-91  1
2009 Raskin AM, Hoshijima M, Swanson E, McCulloch AD, Omens JH. Hypertrophic gene expression induced by chronic stretch of excised mouse heart muscle. Molecular & Cellular Biomechanics : McB. 6: 145-59. PMID 19670825  1
2009 Kita-Matsuo H, Barcova M, Prigozhina N, Salomonis N, Wei K, Jacot JG, Nelson B, Spiering S, Haverslag R, Kim C, Talantova M, Bajpai R, Calzolari D, Terskikh A, McCulloch AD, et al. Lentiviral vectors and protocols for creation of stable hESC lines for fluorescent tracking and drug resistance selection of cardiomyocytes. Plos One. 4: e5046. PMID 19352491 DOI: 10.1371/journal.pone.0005046  1
2009 Lu S, Michailova A, Saucerman J, Cheng Y, Yu Z, Kaiser T, Li W, Bank R, Holst M, McCammon J, Hayashi T, Hoshijima M, Arzberger P, McCulloch A. Multiscale modeling in rodent ventricular myocytes. Ieee Engineering in Medicine and Biology Magazine : the Quarterly Magazine of the Engineering in Medicine & Biology Society. 28: 46-57. PMID 19349251 DOI: 10.1109/MEMB.2009.931787  1
2009 Campbell SG, Howard E, Aguado-Sierra J, Coppola BA, Omens JH, Mulligan LJ, McCulloch AD, Kerckhoffs RC. Effect of transmurally heterogeneous myocyte excitation-contraction coupling on canine left ventricular electromechanics. Experimental Physiology. 94: 541-52. PMID 19251984 DOI: 10.1113/expphysiol.2008.044057  1
2009 Kerckhoffs RC, McCulloch AD, Omens JH, Mulligan LJ. Effects of biventricular pacing and scar size in a computational model of the failing heart with left bundle branch block. Medical Image Analysis. 13: 362-9. PMID 18675578 DOI: 10.1016/j.media.2008.06.013  1
2009 McCulloch AD. Systems biology and multi-scale modeling of the heart 2009 1st Annual Ornl Biomedical Science and Engineering Conference, Bsec 2009. DOI: 10.1109/BSEC.2009.5090455  1
2009 Evans SM, Cai CL, Martin JC, Sun Y, Cui L, Wang L, Ouyang K, Yang L, Bu L, Liang X, Zhang X, Stallcup WB, Denton CP, McCulloch A, Chen J. Cai et al. reply Nature. 458: E9-E10. DOI: 10.1038/nature07917  1
2008 Calzolari D, Bruschi S, Coquin L, Schofield J, Feala JD, Reed JC, McCulloch AD, Paternostro G. Search algorithms as a framework for the optimization of drug combinations. Plos Computational Biology. 4: e1000249. PMID 19112483 DOI: 10.1371/journal.pcbi.1000249  1
2008 Coquin L, Feala JD, McCulloch AD, Paternostro G. Metabolomic and flux-balance analysis of age-related decline of hypoxia tolerance in Drosophila muscle tissue. Molecular Systems Biology. 4: 233. PMID 19096360 DOI: 10.1038/msb.2008.71  1
2008 Sheikh F, Raskin A, Chu PH, Lange S, Domenighetti AA, Zheng M, Liang X, Zhang T, Yajima T, Gu Y, Dalton ND, Mahata SK, Dorn GW, Brown JH, Heller-Brown J, ... ... McCulloch AD, et al. An FHL1-containing complex within the cardiomyocyte sarcomere mediates hypertrophic biomechanical stress responses in mice. The Journal of Clinical Investigation. 118: 3870-80. PMID 19033658 DOI: 10.1172/JCI34472  1
2008 Rudy Y, Ackerman MJ, Bers DM, Clancy CE, Houser SR, London B, McCulloch AD, Przywara DA, Rasmusson RL, Solaro RJ, Trayanova NA, Van Wagoner DR, Varró A, Weiss JN, Lathrop DA. Systems approach to understanding electromechanical activity in the human heart: a national heart, lung, and blood institute workshop summary. Circulation. 118: 1202-11. PMID 18779456 DOI: 10.1161/CIRCULATIONAHA.108.772715  1
2008 Mills RW, Narayan SM, McCulloch AD. Mechanisms of conduction slowing during myocardial stretch by ventricular volume loading in the rabbit. American Journal of Physiology. Heart and Circulatory Physiology. 295: H1270-H1278. PMID 18660447 DOI: 10.1152/ajpheart.00350.2008  1
2008 Lim BK, Xiong D, Dorner A, Youn TJ, Yung A, Liu TI, Gu Y, Dalton ND, Wright AT, Evans SM, Chen J, Peterson KL, McCulloch AD, Yajima T, Knowlton KU. Coxsackievirus and adenovirus receptor (CAR) mediates atrioventricular-node function and connexin 45 localization in the murine heart. The Journal of Clinical Investigation. 118: 2758-70. PMID 18636119 DOI: 10.1172/JCI34777  1
2008 Kerckhoffs RC, Narayan SM, Omens JH, Mulligan LJ, McCulloch AD. Computational modeling for bedside application. Heart Failure Clinics. 4: 371-8. PMID 18598988 DOI: 10.1016/j.hfc.2008.02.009  1
2008 Campbell SG, Flaim SN, Leem CH, McCulloch AD. Mechanisms of transmurally varying myocyte electromechanics in an integrated computational model. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 366: 3361-80. PMID 18593662 DOI: 10.1098/rsta.2008.0088  1
2008 Jacot JG, McCulloch AD, Omens JH. Substrate stiffness affects the functional maturation of neonatal rat ventricular myocytes. Biophysical Journal. 95: 3479-87. PMID 18586852 DOI: 10.1529/biophysj.107.124545  1
2008 Michailova A, McCulloch AD. Effects of Mg2+, pH and PCr on cardiac excitation-metabolic coupling. Magnesium Research : Official Organ of the International Society For the Development of Research On Magnesium. 21: 16-28. PMID 18557130 DOI: 10.1684/mrh.2008.0126  1
2008 Campbell PH, Hunt DL, Jones Y, Harwood F, Amiel D, Omens JH, McCulloch AD. Effects of biglycan deficiency on myocardial infarct structure and mechanics. Molecular & Cellular Biomechanics : McB. 5: 27-35. PMID 18524244  1
2008 Cai CL, Martin JC, Sun Y, Cui L, Wang L, Ouyang K, Yang L, Bu L, Liang X, Zhang X, Stallcup WB, Denton CP, McCulloch A, Chen J, Evans SM. A myocardial lineage derives from Tbx18 epicardial cells. Nature. 454: 104-8. PMID 18480752 DOI: 10.1038/nature06969  1
2008 Kerckhoffs RC, Lumens J, Vernooy K, Omens JH, Mulligan LJ, Delhaas T, Arts T, McCulloch AD, Prinzen FW. Cardiac resynchronization: insight from experimental and computational models. Progress in Biophysics and Molecular Biology. 97: 543-61. PMID 18417196 DOI: 10.1016/j.pbiomolbio.2008.02.024  1
2008 Zhang Y, Sekar RB, McCulloch AD, Tung L. Cell cultures as models of cardiac mechanoelectric feedback. Progress in Biophysics and Molecular Biology. 97: 367-82. PMID 18384846 DOI: 10.1016/j.pbiomolbio.2008.02.017  1
2008 Feala JD, Omens JH, Paternostro G, McCulloch AD. Discovering regulators of the Drosophila cardiac hypoxia response using automated phenotyping technology. Annals of the New York Academy of Sciences. 1123: 169-77. PMID 18375589 DOI: 10.1196/annals.1420.019  1
2008 Li W, Gurev V, McCulloch AD, Trayanova NA. The role of mechanoelectric feedback in vulnerability to electric shock. Progress in Biophysics and Molecular Biology. 97: 461-78. PMID 18374394 DOI: 10.1016/j.pbiomolbio.2008.02.020  1
2008 Feala JD, Coquin L, Paternostro G, McCulloch AD. Integrating metabolomics and phenomics with systems models of cardiac hypoxia. Progress in Biophysics and Molecular Biology. 96: 209-25. PMID 17870149 DOI: 10.1016/j.pbiomolbio.2007.07.014  1
2008 Waldman L, Cunanan C, Asrani S, Kerckhoffs R, McCulloch A. Computational mechanics of the sclera and optic nerve head (ONH): Effects of ONH size and pressure range 2008 Proceedings of the 3rd Frontiers in Biomedical Devices Conference and Exhibition. 9-10.  1
2007 Flaim SN, McCulloch AD. Acetylcholine-induced shortening of the epicardial action potential duration may increase repolarization gradients and LQT3 arrhythmic risk. Journal of Electrocardiology. 40: S66-9. PMID 17993332 DOI: 10.1016/j.jelectrocard.2007.06.010  1
2007 Zemljic-Harpf AE, Miller JC, Henderson SA, Wright AT, Manso AM, Elsherif L, Dalton ND, Thor AK, Perkins GA, McCulloch AD, Ross RS. Cardiac-myocyte-specific excision of the vinculin gene disrupts cellular junctions, causing sudden death or dilated cardiomyopathy. Molecular and Cellular Biology. 27: 7522-37. PMID 17785437 DOI: 10.1128/MCB.00728-07  1
2007 Flaim SN, Giles WR, McCulloch AD. Arrhythmogenic consequences of Na+ channel mutations in the transmurally heterogeneous mammalian left ventricle: analysis of the I1768V SCN5A mutation. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 4: 768-78. PMID 17556201 DOI: 10.1016/j.hrthm.2007.02.009  1
2007 Broderick KE, Balasubramanian M, Chan A, Potluri P, Feala J, Belke DD, McCulloch A, Sharma VS, Pilz RB, Bigby TD, Boss GR. The cobalamin precursor cobinamide detoxifies nitroprusside-generated cyanide Experimental Biology and Medicine. 232: 789-798. PMID 17526771  1
2007 Coppola BA, Covell JW, McCulloch AD, Omens JH. Asynchrony of ventricular activation affects magnitude and timing of fiber stretch in late-activated regions of the canine heart. American Journal of Physiology. Heart and Circulatory Physiology. 293: H754-61. PMID 17449547 DOI: 10.1152/ajpheart.01225.2006  1
2007 Feala JD, Coquin L, McCulloch AD, Paternostro G. Flexibility in energy metabolism supports hypoxia tolerance in Drosophila flight muscle: metabolomic and computational systems analysis. Molecular Systems Biology. 3: 99. PMID 17437024 DOI: 10.1038/msb4100139  1
2007 Costandi PN, McCulloch AD, Omens JH, Frank LR. High-resolution longitudinal MRI of the transition to heart failure. Magnetic Resonance in Medicine. 57: 714-20. PMID 17390366 DOI: 10.1002/mrm.21182  1
2007 Michailova A, Lorentz W, McCulloch A. Modeling transmural heterogeneity of KATP current in rabbit ventricular myocytes American Journal of Physiology - Cell Physiology. 293: C542-C557. PMID 17329404 DOI: 10.1152/ajpcell.00148.2006  1
2007 Kerckhoffs RC, Neal ML, Gu Q, Bassingthwaighte JB, Omens JH, McCulloch AD. Coupling of a 3D finite element model of cardiac ventricular mechanics to lumped systems models of the systemic and pulmonic circulation. Annals of Biomedical Engineering. 35: 1-18. PMID 17111210 DOI: 10.1007/s10439-006-9212-7  1
2007 Ingrassia CM, Usyk TP, Kerckhoffs RCP, McCulloch AD, Costa KD, Holmes JW. Model-based development of four-dimensional wall motion measures Computer Methods in Applied Mechanics and Engineering. 196: 3061-3069. DOI: 10.1016/j.cma.2006.06.016  1
2007 Kerckhoffs RCP, McCulloch AD, Omens JH, Mulligan LJ. Effect of pacing site and infarct location on regional mechanics and global hemodynamics in a model based study of heart failure Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 4466: 350-360.  1
2006 Camelliti P, Gallagher JO, Kohl P, McCulloch AD. Micropatterned cell cultures on elastic membranes as an in vitro model of myocardium. Nature Protocols. 1: 1379-91. PMID 17406425 DOI: 10.1038/nprot.2006.203  1
2006 Saucerman JJ, McCulloch AD. Cardiac beta-adrenergic signaling: from subcellular microdomains to heart failure. Annals of the New York Academy of Sciences. 1080: 348-61. PMID 17132794 DOI: 10.1196/annals.1380.026  1
2006 Lorenzen-Schmidt I, Schmid-Schönbein GW, Giles WR, McCulloch AD, Chien S, Omens JH. Chronotropic response of cultured neonatal rat ventricular myocytes to short-term fluid shear. Cell Biochemistry and Biophysics. 46: 113-22. PMID 17012753 DOI: 10.1385/CBB:46:2:113  1
2006 Saucerman JJ, Zhang J, Martin JC, Peng LX, Stenbit AE, Tsien RY, McCulloch AD. Systems analysis of PKA-mediated phosphorylation gradients in live cardiac myocytes. Proceedings of the National Academy of Sciences of the United States of America. 103: 12923-8. PMID 16905651 DOI: 10.1073/pnas.0600137103  1
2006 Costandi PN, Frank LR, McCulloch AD, Omens JH. Role of diastolic properties in the transition to failure in a mouse model of the cardiac dilatation. American Journal of Physiology. Heart and Circulatory Physiology. 291: H2971-9. PMID 16861693 DOI: 10.1152/ajpheart.00571.2006  1
2006 Flaim SN, Giles WR, McCulloch AD. Contributions of sustained INa and IKv43 to transmural heterogeneity of early repolarization and arrhythmogenesis in canine left ventricular myocytes. American Journal of Physiology. Heart and Circulatory Physiology. 291: H2617-29. PMID 16829642 DOI: 10.1152/ajpheart.00350.2006  1
2006 McCulloch AD, Omens JH. Myocyte shearing, myocardial sheets, and microtubules. Circulation Research. 98: 1-3. PMID 16397149 DOI: 10.1161/01.RES.0000200395.82480.8d  1
2006 Hunter PJ, Li WW, McCulloch AD, Noble D. Multiscale modeling: Physiome project standards, tools, and databases Computer. 39: 48-54. DOI: 10.1109/MC.2006.392  1
2006 Kerckhoffs RCP, Healy SN, Usyk TP, Mcculloch AD. Computational methods for cardiac electromechanics Proceedings of the Ieee. 94: 769-782. DOI: 10.1109/JPROC.2006.871772  1
2005 Healy SN, McCulloch AD. An ionic model of stretch-activated and stretch-modulated currents in rabbit ventricular myocytes. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. 7: 128-34. PMID 16102510 DOI: 10.1016/j.eupc.2005.03.019  1
2005 Sarraf CE, Harris AB, McCulloch AD, Eastwood M. Cell proliferation rates in an artificial tissue-engineered environment. Cell Proliferation. 38: 215-21. PMID 16098181 DOI: 10.1111/j.1365-2184.2005.00347.x  1
2005 McCulloch AD, Paternostro G. Cardiac systems biology. Annals of the New York Academy of Sciences. 1047: 283-95. PMID 16093504 DOI: 10.1196/annals.1341.025  1
2005 Camelliti P, McCulloch AD, Kohl P. Microstructured cocultures of cardiac myocytes and fibroblasts: a two-dimensional in vitro model of cardiac tissue. Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 11: 249-59. PMID 16060978 DOI: 10.1017/S1431927605050506  1
2005 Lorenzen-Schmidt I, McCulloch AD, Omens JH. Deficiency of actinin-associated LIM protein alters regional right ventricular function and hypertrophic remodeling. Annals of Biomedical Engineering. 33: 888-96. PMID 16060528 DOI: 10.1007/s10439-005-3604-y  1
2005 Lorenzen-Schmidt I, Stuyvers BD, ter Keurs HE, Date MO, Hoshijima M, Chien KR, McCulloch AD, Omens JH. Young MLP deficient mice show diastolic dysfunction before the onset of dilated cardiomyopathy. Journal of Molecular and Cellular Cardiology. 39: 241-50. PMID 15978612 DOI: 10.1016/j.yjmcc.2005.05.006  1
2005 Weis SM, Zimmerman SD, Shah M, Covell JW, Omens JH, Ross J, Dalton N, Jones Y, Reed CC, Iozzo RV, McCulloch AD. A role for decorin in the remodeling of myocardial infarction. Matrix Biology : Journal of the International Society For Matrix Biology. 24: 313-24. PMID 15949932 DOI: 10.1016/j.matbio.2005.05.003  1
2005 Michailova A, Saucerman J, Belik ME, McCulloch AD. Modeling regulation of cardiac KATP and L-type Ca2+ currents by ATP, ADP, and Mg2+. Biophysical Journal. 88: 2234-49. PMID 15738467 DOI: 10.1529/biophysj.104.046284  1
2005 Ferrarini L, Bertelli L, Feala J, McCulloch AD, Paternostro G. A more efficient search strategy for aging genes based on connectivity. Bioinformatics (Oxford, England). 21: 338-48. PMID 15347572 DOI: 10.1093/bioinformatics/bti004  1
2005 McCulloch AD, Gallagher JO, Bhatia SN, Borg TK, Omens JH. Three-dimensional micropatterned cardiac tissue cultures Microscopy and Microanalysis. 11: 110-111. DOI: 10.1017/S1431927605509504  1
2004 McCulloch AD. Functionally and structurally integrated computational modeling of ventricular physiology. The Japanese Journal of Physiology. 54: 531-9. PMID 15760485 DOI: 10.2170/jjphysiol.54.531  1
2004 Chen L, McCulloch AD, May-Newman K. Nonhomogeneous deformation in the anterior leaflet of the mitral valve. Annals of Biomedical Engineering. 32: 1599-606. PMID 15675673  1
2004 Saucerman JJ, Healy SN, Belik ME, Puglisi JL, McCulloch AD. Proarrhythmic consequences of a KCNQ1 AKAP-binding domain mutation: computational models of whole cells and heterogeneous tissue. Circulation Research. 95: 1216-24. PMID 15528464 DOI: 10.1161/01.RES.0000150055.06226.4e  1
2004 Michailova AP, Belik ME, McCulloch AD. Effects of magnesium on cardiac excitation-contraction coupling. Journal of the American College of Nutrition. 23: 514S-517S. PMID 15466954  1
2004 Buckberg GD, Weisfeldt ML, Ballester M, Beyar R, Burkhoff D, Coghlan HC, Doyle M, Epstein ND, Gharib M, Ideker RE, Ingels NB, LeWinter MM, McCulloch AD, Pohost GM, Reinlib LJ, et al. Left ventricular form and function: scientific priorities and strategic planning for development of new views of disease. Circulation. 110: e333-6. PMID 15466651 DOI: 10.1161/01.CIR.0000143625.56882.5C  1
2004 McCulloch AD, Harris AB, Sarraf CE, Eastwood M. New multi-cue bioreactor for tissue engineering of tubular cardiovascular samples under physiological conditions. Tissue Engineering. 10: 565-73. PMID 15165473 DOI: 10.1089/107632704323061924  1
2004 Saucerman JJ, McCulloch AD. Mechanistic systems models of cell signaling networks: a case study of myocyte adrenergic regulation. Progress in Biophysics and Molecular Biology. 85: 261-78. PMID 15142747 DOI: 10.1016/j.pbiomolbio.2004.01.005  1
2004 Shah SB, Davis J, Weisleder N, Kostavassili I, McCulloch AD, Ralston E, Capetanaki Y, Lieber RL. Structural and functional roles of desmin in mouse skeletal muscle during passive deformation. Biophysical Journal. 86: 2993-3008. PMID 15111414 DOI: 10.1016/S0006-3495(04)74349-0  1
2004 Belik ME, Usyk TP, McCulloch AD. Computational Methods for Cardiac Electrophysiology Handbook of Numerical Analysis. 12: 129-187. DOI: 10.1016/S1570-8659(03)12002-9  1
2003 Usyk TP, McCulloch AD. Relationship between regional shortening and asynchronous electrical activation in a three-dimensional model of ventricular electromechanics. Journal of Cardiovascular Electrophysiology. 14: S196-202. PMID 14760924  1
2003 Usyk TP, McCulloch AD. Electromechanical model of cardiac resynchronization in the dilated failing heart with left bundle branch block. Journal of Electrocardiology. 36: 57-61. PMID 14716593 DOI: 10.1016/j.jelectrocard.2003.09.015  1
2003 Omens JH, McCulloch AD, Criscione JC. Complex distributions of residual stress and strain in the mouse left ventricle: experimental and theoretical models. Biomechanics and Modeling in Mechanobiology. 1: 267-77. PMID 14586695 DOI: 10.1007/s10237-002-0021-0  0.72
2003 Sarraf CE, Harris AB, McCulloch AD, Eastwood M. Heart valve and arterial tissue engineering. Cell Proliferation. 36: 241-54. PMID 14521518 DOI: 10.1046/j.1365-2184.2003.00281.x  1
2003 Saucerman JJ, Brunton LL, Michailova AP, McCulloch AD. Modeling beta-adrenergic control of cardiac myocyte contractility in silico. The Journal of Biological Chemistry. 278: 47997-8003. PMID 12972422 DOI: 10.1074/jbc.M308362200  1
2003 Sung D, Mills RW, Schettler J, Narayan SM, Omens JH, McCulloch AD. Ventricular filling slows epicardial conduction and increases action potential duration in an optical mapping study of the isolated rabbit heart. Journal of Cardiovascular Electrophysiology. 14: 739-49. PMID 12930255  1
2003 Herrmann KL, McCulloch AD, Omens JH. Glycated collagen cross-linking alters cardiac mechanics in volume-overload hypertrophy. American Journal of Physiology. Heart and Circulatory Physiology. 284: H1277-84. PMID 12595292 DOI: 10.1152/ajpheart.00168.2002  1
2003 Gopalan SM, Flaim C, Bhatia SN, Hoshijima M, Knoell R, Chien KR, Omens JH, McCulloch AD. Anisotropic stretch-induced hypertrophy in neonatal ventricular myocytes micropatterned on deformable elastomers. Biotechnology and Bioengineering. 81: 578-87. PMID 12514807 DOI: 10.1002/bit.10506  1
2003 Burton MC, Griswold WG, McCulloch AD, Huber GA. Static Data Structures: Reconciling template metaprogramming and generic programming Ifip Advances in Information and Communication Technology. 115: 141-169. DOI: 10.1007/978-0-387-35672-3  1
2002 Sarraf CE, Harris AB, McCulloch AD, Eastwood M. Tissue engineering of biological cardiovascular system surrogates. Heart, Lung & Circulation. 11: 142-50; discussion 1. PMID 16352087 DOI: 10.1046/j.1444-2892.2002.00150.x  1
2002 McCulloch AD, Huber G. Integrative biological modelling in silico Novartis Foundation Symposium. 247: 4-25. PMID 12539946  1
2002 Knöll R, Hoshijima M, Hoffman HM, Person V, Lorenzen-Schmidt I, Bang ML, Hayashi T, Shiga N, Yasukawa H, Schaper W, McKenna W, Yokoyama M, Schork NJ, Omens JH, McCulloch AD, et al. The cardiac mechanical stretch sensor machinery involves a Z disc complex that is defective in a subset of human dilated cardiomyopathy. Cell. 111: 943-55. PMID 12507422 DOI: 10.1016/S0092-8674(02)01226-6  1
2002 Stuyvers BD, McCulloch AD, Guo J, Duff HJ, Ter Keurs HEDJ. Effect of stimulation rate, sarcomere length and Ca2+ on force generation by mouse cardiac muscle Journal of Physiology. 544: 817-830. PMID 12411526 DOI: 10.1113/jphysiol.2002.024430  1
2002 Omens JH, Usyk TP, Li Z, McCulloch AD. Muscle LIM protein deficiency leads to alterations in passive ventricular mechanics. American Journal of Physiology. Heart and Circulatory Physiology. 282: H680-7. PMID 11788418 DOI: 10.1152/ajpheart.00773.2001  1
2002 Criscione JC, McCulloch AD, Hunter WC. Constitutive framework optimized for myocardium and other high-strain, laminar materials with one fiber family Journal of the Mechanics and Physics of Solids. 50: 1681-1702. DOI: 10.1016/S0022-5096(01)00138-7  1
2002 Usyk TP, LeGrice IJ, McCulloch AD. Computational model of three-dimensional cardiac electromechanics Computing and Visualization in Science. 4: 249-257. DOI: 10.1007/s00791-002-0081-9  1
2002 Sarraf CE, Harris AB, McCulloch AD, Eastwood M. Rate of entry into mitosis of a primary culture of myofibroblasts seeded in vitro into a synthetic substrate Third Smith and Nephew International Symposium - Translating Tissue Engineering Into Products. 98.  1
2002 Usyk TP, Belik ME, Michailova A, McCulloch AD. Three-dimensional model of cardiac electromechanics: Cell to organ Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 2: 1220-1221.  1
2002 Saucerman JJ, Michailova AP, McCulloch AD. Modeling biochemical networks and excitation-contraction coupling Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 3: 2235-2236.  1
2002 McCulloch AD, Harris AB, Sarraf CE, Eastwood M. Applications for the multi-cue bioreactor (M-CB): Dynamic in-vitro testing of whole cardiovascular tissue samples under physiological conditions Third Smith and Nephew International Symposium - Translating Tissue Engineering Into Products. 134.  1
2002 Harris AB, Sarraf CE, McCulloch AD, Eastwood M. In vitro tissue engineering of cardiovascular substitutes Third Smith and Nephew International Symposium - Translating Tissue Engineering Into Products. 64.  1
2001 Sung D, Somayajula-Jagai J, Cosman P, Mills R, McCulloch AD. Phase shifting prior to spatial filtering enhances optical recordings of cardiac action potential propagation Annals of Biomedical Engineering. 29: 854-861. PMID 11764316 DOI: 10.1114/1.1408927  1
2001 Baxter WW, McCulloch AD. In vivo finite element model-based image analysis of pacemaker lead mechanics Medical Image Analysis. 5: 255-270. PMID 11731305 DOI: 10.1016/S1361-8415(01)00041-X  1
2001 Gregersen H, Weis SM, McCulloch AD. Oesophageal morphometry and residual strain in a mouse model of osteogenesis imperfecta. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 13: 457-64. PMID 11696107 DOI: 10.1046/j.1365-2982.2001.00279.x  1
2001 McCulloch AD, Mazhari R. Regional myocardial mechanics: Integrative computational models of flow-function relations Journal of Nuclear Cardiology. 8: 506-519. PMID 11481573 DOI: 10.1067/mnc.2001.117113  1
2001 Mazhari R, Omens JH, Pavelec RS, Covell JW, McCulloch AD. Transmural distribution of three-dimensional systolic strains in stunned myocardium Circulation. 104: 336-341. PMID 11457754  1
2001 Usyk TP, Omens JH, McCulloch AD. Regional septal dysfunction in a three-dimensional computational model of focal myofiber disarray American Journal of Physiology - Heart and Circulatory Physiology. 281: H506-H514. PMID 11454551  1
2001 Vetter FJ, McCulloch AD. Mechanoelectric feedback in a model of the passively inflated left ventricle Annals of Biomedical Engineering. 29: 414-426. PMID 11400722 DOI: 10.1114/1.1366670  1
2001 Paternostro G, Vignola C, Bartsch DU, Omens JH, McCulloch AD, Reed JC. Age-associated cardiac dysfunction in Drosophila melanogaster Circulation Research. 88: 1053-1058. PMID 11375275  1
2001 Arts T, Costa KD, Covell JW, McCulloch AD. Relating myocardial laminar architecture to shear strain and muscle fiber orientation American Journal of Physiology - Heart and Circulatory Physiology. 280: H2222-H2229. PMID 11299225  1
2001 Young AA, Dokos S, Powell KA, Sturm B, McCulloch AD, Starling RC, McCarthy PM, White RD. Regional heterogeneity of function in nonischemic dilated cardiomyopathy Cardiovascular Research. 49: 308-318. PMID 11164841 DOI: 10.1016/S0008-6363(00)00248-0  1
2001 Costa KD, Holmes JW, McCulloch AD. Modelling cardiac mechanical properties in three dimensions Philosophical Transactions of the Royal Society a: Mathematical, Physical and Engineering Sciences. 359: 1233-1250. DOI: 10.1098/rsta.2001.0828  1
2001 Sung D, Omens JH, McCulloch AD. Ventricular mechano-electric feedback in the isolated rabbit heart American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 50: 683-684.  1
2001 Omens JH, Usyk TP, McCulloch AD. Role of the cytoskeleton in cardiac growth and remodeling American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 50: 641-642.  1
2001 McCulloch AD, Sung D, Thomas ME, Michailova A. Experimental and computational modeling of cardiac electromechanical coupling Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 2230: 113-119.  0.4
2000 O'Dell WG, McCulloch AD. Imaging three-dimensional cardiac function Annual Review of Biomedical Engineering. 2: 431-456. PMID 11701519  1
2000 Mazhari R, McCulloch AD. Integrative models for understanding the structural basis of regional mechanical dysfunction in ischemic myocardium Annals of Biomedical Engineering. 28: 979-990. PMID 11144683 DOI: 10.1114/1.1308502  1
2000 Sung D, Omens JH, McCulloch AD. Model-based analysis of optically mapped epicardial activation patterns and conduction velocity Annals of Biomedical Engineering. 28: 1085-1092. PMID 11132192 DOI: 10.1114/1.1314891  1
2000 McCulloch AD. Modeling the human cardiome in silico Journal of Nuclear Cardiology. 7: 496-499. PMID 11083199  1
2000 Weis SM, Emery JL, Becker KD, McBride DJ, Omens JH, McCulloch AD. Myocardial mechanics and collagen structure in the osteogenesis imperfecta murine (oim). Circulation Research. 87: 663-9. PMID 11029401  1
2000 Vetter FJ, Mcculloch AD. Three-Dimensional Stress and Strain in Passive Rabbit Left Ventricle: A Model Study Annals of Biomedical Engineering. 28: 781-792. PMID 11016415  1
2000 Mazhari R, Omens JH, Covell JW, McCulloch AD. Structural basis of regional dysfunction in acutely ischemic myocardium Cardiovascular Research. 47: 284-293. PMID 10946065 DOI: 10.1016/S0008-6363(00)00089-4  1
2000 Karlon WJ, McCulloch AD, Covell JW, Hunter JJ, Omens JH. Regional dysfunction correlates with myofiber disarray in transgenic mice with ventricular expression of ras American Journal of Physiology - Heart and Circulatory Physiology. 278: H898-H906. PMID 10710359  1
2000 Usyk TP, Mazhari R, Mcculloch AD. Effect of laminar orthotropic myofiber architecture on regional stress and strain in the canine left ventricle Journal of Elasticity. 61: 143-164. DOI: 10.1023/A:1010883920374  1
1999 Karlon WJ, Hsu PP, Song LI, Chien S, McCulloch AD, Omens JH. Measurement of Orientation and Distribution of Cellular Alignment and Cytoskeletal Organization Annals of Biomedical Engineering. 27: 712-720. PMID 10625144  1
1999 Lee AA, Delhaas T, McCulloch AD, Villarreal FJ. Differential responses of adult cardiac fibroblasts to in vitro biaxial strain patterns Journal of Molecular and Cellular Cardiology. 31: 1833-1843. PMID 10525421 DOI: 10.1006/jmcc.1999.1017  1
1999 Costa KD, Takayama Y, McCulloch AD, Covell JW. Laminar fiber architecture and three-dimensional systolic mechanics in canine ventricular myocardium American Journal of Physiology - Heart and Circulatory Physiology. 276: H595-H607. PMID 9950861  1
1999 Mazhari R, McCulloch AD. Three-dimensional mechanics of myocardial contraction: mechanisms of transverse systolic stress American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 42: 43-44.  1
1999 Vaplon SM, Omens JH, McCulloch AD. Ventricular tissue adaptation associated with collagen deficiency in the osteogenesis imperfecta murine American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 42: 691-692.  1
1999 Mazhari R, Omens JH, Covell JW, McCulloch AD. Structural determinants of the functional border zone in acutely ischemic myocardium American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 42: 211-212.  1
1998 Omens JH, Vaplon SM, Fazeli B, McCulloch AD. Left ventricular geometric remodeling and residual stress in the rat heart Journal of Biomechanical Engineering. 120: 715-719. PMID 10412454  1
1998 Summerour SR, Emery JL, Fazeli B, Omens JH, McCulloch AD. Residual strain in ischemic ventricular myocardium Journal of Biomechanical Engineering. 120: 710-714. PMID 10412453  1
1998 Bluhm WF, Sung D, Lew WYW, Garfinkel A, McCulloch AD. Cellular mechanisms for the slow phase of the Frank-Starling response Journal of Electrocardiology. 31: 13-22. PMID 9988000 DOI: 10.1016/S0022-0736(98)90273-4  1
1998 Karlon WJ, Covell JW, Mcculloch AD, Hunter JJ, Omens JH. Automated measurement of myofiber disarray in transgenic mice with ventricular expression of ras Anatomical Record. 252: 612-625. PMID 9845212 DOI: 10.1002/(SICI)1097-0185(199812)252:4<612::AID-AR12>3.0.CO;2-1  1
1998 May-Newman K, McCulloch AD. Homogenization modeling for the mechanics of perfused myocardium Progress in Biophysics and Molecular Biology. 69: 463-481. PMID 9785951 DOI: 10.1016/S0079-6107(98)00020-0  1
1998 Hunter PJ, McCulloch AD, ter Keurs HE. Modelling the mechanical properties of cardiac muscle. Progress in Biophysics and Molecular Biology. 69: 289-331. PMID 9785944 DOI: 10.1016/S0079-6107(98)00013-3  1
1998 Vetter FJ, McCulloch AD. Three-dimensional analysis of regional cardiac function: A model of rabbit ventricular anatomy Progress in Biophysics and Molecular Biology. 69: 157-183. PMID 9785937 DOI: 10.1016/S0079-6107(98)00006-6  1
1998 Gregersen H, Emery JL, Mcculloch AD. History-dependent mechanical behavior of guinea-pig small intestine Annals of Biomedical Engineering. 26: 850-858. PMID 9779958  1
1998 Mazhari R, Omens JH, Waldman LK, Mcculloch AD. Regional myocardial perfusion and mechanics: A model-based method of analysis Annals of Biomedical Engineering. 26: 743-755. PMID 9779946  1
1998 McCulloch AD, Sung D, Wilson JM, Pavelec RS, Omens JH. Flow-function relations during graded coronary occlusions in the dog: Effects of transmural location and segment orientation Cardiovascular Research. 37: 636-645. PMID 9659447 DOI: 10.1016/S0008-6363(97)00290-3  1
1998 Hennighausen H, Feldman ST, Bille JF, McCulloch AD. Anterior-posterior strain variation in normally hydrated and swollen rabbit cornea Investigative Ophthalmology and Visual Science. 39: 253-262. PMID 9477981  1
1998 O'Dell WG, McCulloch AD. A novel numerical formulation for modeling tissue compressibility American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 39: 391-392.  1
1998 Vetter FJ, Rogers JM, McCulloch AD. A finite element model of passive mechanics and electrical propagation in the rabbit ventricles Computers in Cardiology. 705-708.  1
1998 Bluhm WF, Lew WYW, Garfinkel A, McCulloch AD. Mechanisms of length history-dependent tension in an ionic model of the cardiac myocyte American Journal of Physiology - Heart and Circulatory Physiology. 43: H1032-H1040.  1
1997 Costa KD, May-Newman K, Farr D, O'Dell WG, McCulloch AD, Omens JH. Three-dimensional residual strain in midanterior canine left ventricle. American Journal of Physiology. Heart and Circulatory Physiology. 273: H1968-H1976. PMID 29586327 DOI: 10.1152/ajpheart.1997.273.4.H1968  1
1997 McCulloch AD. Three-dimensional residual strain in midanterior canine left ventricle American Journal of Physiology - Heart and Circulatory Physiology. 273: H1968-H1976. PMID 9362268  1
1997 Lee AA, McCulloch AD. Multiaxial myocardial mechanics and extracellular matrix remodeling: Mechanochemical regulation of cardiac fibroblast function Advances in Experimental Medicine and Biology. 430: 227-240. PMID 9330732  1
1997 Delhaas T, Clemmens J, Lee AA, McCulloch AD, Villarreal FJ. Effects of tensile and compressive strains on extracellular matrix mRNAs in cultured adult rat cardiac fibroblast Faseb Journal. 11: A281.  1
1997 Emery JL, Omens JH, McCulloch AD. Biaxial mechanics of the passively overstretched left ventricle American Journal of Physiology - Heart and Circulatory Physiology. 41: H2299-H2305.  1
1997 Karlon WJ, Covell JW, McCulloch AD, Omens JH. Ventricular mechanics in a transgenic mouse model of familial hypertrophic cardiomyopathy American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 35: 469-470.  1
1997 Delhaas T, Lee AA, Clemmens JS, Villarreal FJ, McCulloch AD. Alterations in gene expression due to equibiaxial extension and compression in cultured cardiac fibroblasts American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 35: 477-478.  1
1997 Mackenna DA, Vaplon SM, Mcculloch AD. Microstructural model of perimysial collagen fibers for resting myocardial mechanics during ventricular filling American Journal of Physiology - Heart and Circulatory Physiology. 42: H1576-H1586.  1
1996 Costa KD, Hunter PJ, Wayne JS, Waldman LK, Guccione JM, McCulloch AD. A three-dimensional finite element method for large elastic deformations of ventricular myocardium: II--Prolate spheroidal coordinates. Journal of Biomechanical Engineering. 118: 464-72. PMID 8950649  1
1996 Costa KD, Hunter PJ, Rogers JM, Guccione JM, Waldman LK, McCulloch AD. A three-dimensional finite element method for large elastic deformations of ventricular myocardium: I--Cylindrical and spherical polar coordinates. Journal of Biomechanical Engineering. 118: 452-63. PMID 8950648  1
1992 McCulloch AD, Hunter PJ, Smaill BH. Mechanical effects of coronary perfusion in the passive canine left ventricle. The American Journal of Physiology. 262: H523-30. PMID 1539711  0.68
1989 McCulloch AD, Smaill BH, Hunter PJ. Regional left ventricular epicardial deformation in the passive dog heart. Circulation Research. 64: 721-33. PMID 2702734  0.68
1987 McCulloch AD, Smaill BH, Hunter PJ. Left ventricular epicardial deformation in isolated arrested dog heart. The American Journal of Physiology. 252: H233-41. PMID 3812713  0.68
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