| Year |
Citation |
Score |
| 2024 |
Ofori-Anyinam B, Hamblin M, Coldren ML, Li B, Mereddy G, Shaikh M, Shah A, Grady C, Ranu N, Lu S, Blainey PC, Ma S, Collins JJ, Yang JH. Catalase activity deficiency sensitizes multidrug-resistant Mycobacterium tuberculosis to the ATP synthase inhibitor bedaquiline. Nature Communications. 15: 9792. PMID 39537610 DOI: 10.1038/s41467-024-53933-8 |
0.474 |
|
| 2021 |
Lopatkin AJ, Yang JH. Digital Insights Into Nucleotide Metabolism and Antibiotic Treatment Failure. Frontiers in Digital Health. 3. PMID 34355212 DOI: 10.3389/fdgth.2021.583468 |
0.696 |
|
| 2021 |
Kim GL, Hooven TA, Norambuena J, Li B, Boyd JM, Yang JH, Parker D. Growth and Stress Tolerance Comprise Independent Metabolic Strategies Critical for Staphylococcus aureus Infection. Mbio. e0081421. PMID 34101490 DOI: 10.1128/mBio.00814-21 |
0.311 |
|
| 2021 |
Lopatkin AJ, Bening SC, Manson AL, Stokes JM, Kohanski MA, Badran AH, Earl AM, Cheney NJ, Yang JH, Collins JJ. Clinically relevant mutations in core metabolic genes confer antibiotic resistance. Science (New York, N.Y.). 371. PMID 33602825 DOI: 10.1126/science.aba0862 |
0.744 |
|
| 2019 |
Lopatkin AJ, Stokes JM, Zheng EJ, Yang JH, Takahashi MK, You L, Collins JJ. Bacterial metabolic state more accurately predicts antibiotic lethality than growth rate. Nature Microbiology. PMID 31451773 DOI: 10.1038/S41564-019-0536-0 |
0.727 |
|
| 2019 |
Yang JH, Wright SN, Hamblin M, McCloskey D, Alcantar MA, Schrübbers L, Lopatkin AJ, Satish S, Nili A, Palsson BO, Walker GC, Collins JJ. A White-Box Machine Learning Approach for Revealing Antibiotic Mechanisms of Action. Cell. PMID 31080069 DOI: 10.1016/J.Cell.2019.04.016 |
0.721 |
|
| 2017 |
Yang JH, Bhargava P, McCloskey D, Mao N, Palsson BO, Collins JJ. Antibiotic-Induced Changes to the Host Metabolic Environment Inhibit Drug Efficacy and Alter Immune Function. Cell Host & Microbe. 22: 757-765.e3. PMID 29199098 DOI: 10.1016/J.Chom.2017.10.020 |
0.639 |
|
| 2017 |
Yang JH, Bening SC, Collins JJ. Antibiotic efficacy-context matters. Current Opinion in Microbiology. 39: 73-80. PMID 29049930 DOI: 10.1016/J.Mib.2017.09.002 |
0.606 |
|
| 2017 |
Takahashi N, Gruber CC, Yang JH, Liu X, Braff D, Yashaswini CN, Bhubhanil S, Furuta Y, Andreescu S, Collins JJ, Walker GC. Lethality of MalE-LacZ hybrid protein shares mechanistic attributes with oxidative component of antibiotic lethality. Proceedings of the National Academy of Sciences of the United States of America. PMID 28794281 DOI: 10.1073/Pnas.1707466114 |
0.536 |
|
| 2017 |
Meylan S, Porter CB, Yang JH, Belenky P, Gutierrez A, Lobritz MA, Park J, Kim SH, Moskowitz SM, Collins JJ. Carbon Sources Tune Antibiotic Susceptibility in Pseudomonas aeruginosa via Tricarboxylic Acid Cycle Control. Cell Chemical Biology. PMID 28111098 DOI: 10.1016/J.Chembiol.2016.12.015 |
0.594 |
|
| 2015 |
Lobritz MA, Belenky P, Porter CB, Gutierrez A, Yang JH, Schwarz EG, Dwyer DJ, Khalil AS, Collins JJ. Antibiotic efficacy is linked to bacterial cellular respiration. Proceedings of the National Academy of Sciences of the United States of America. PMID 26100898 DOI: 10.1073/Pnas.1509743112 |
0.719 |
|
| 2014 |
Dwyer DJ, Belenky PA, Yang JH, MacDonald IC, Martell JD, Takahashi N, Chan CT, Lobritz MA, Braff D, Schwarz EG, Ye JD, Pati M, Vercruysse M, Ralifo PS, Allison KR, et al. Antibiotics induce redox-related physiological alterations as part of their lethality. Proceedings of the National Academy of Sciences of the United States of America. 111: E2100-9. PMID 24803433 DOI: 10.1073/Pnas.1401876111 |
0.73 |
|
| 2014 |
Yang JH, Polanowska-Grabowska RK, Smith JS, Shields CW, Saucerman JJ. PKA catalytic subunit compartmentation regulates contractile and hypertrophic responses to β-adrenergic signaling. Journal of Molecular and Cellular Cardiology. 66: 83-93. PMID 24225179 DOI: 10.1016/J.Yjmcc.2013.11.001 |
0.605 |
|
| 2013 |
Sample V, DiPilato LM, Yang JH, Ni Q, Saucerman JJ, Zhang J. Erratum: Corrigendum: Regulation of nuclear PKA revealed by spatiotemporal manipulation of cyclic AMP Nature Chemical Biology. 9: 406-406. DOI: 10.1038/Nchembio0613-406B |
0.61 |
|
| 2012 |
Sample V, DiPilato LM, Yang JH, Ni Q, Saucerman JJ, Zhang J. Regulation of nuclear PKA revealed by spatiotemporal manipulation of cyclic AMP. Nature Chemical Biology. 8: 375-82. PMID 22366721 DOI: 10.1038/Nchembio.799 |
0.619 |
|
| 2012 |
Yang JH, Saucerman JJ. Phospholemman is a negative feed-forward regulator of Ca2+ in β-adrenergic signaling, accelerating β-adrenergic inotropy. Journal of Molecular and Cellular Cardiology. 52: 1048-55. PMID 22289214 DOI: 10.1016/J.Yjmcc.2011.12.015 |
0.589 |
|
| 2011 |
Yang JH, Saucerman JJ. Computational models reduce complexity and accelerate insight into cardiac signaling networks. Circulation Research. 108: 85-97. PMID 21212391 DOI: 10.1161/Circresaha.110.223602 |
0.586 |
|
| 2011 |
Benedict KF, Mac Gabhann F, Amanfu RK, Chavali AK, Gianchandani EP, Glaw LS, Oberhardt MA, Thorne BC, Yang JH, Papin JA, Peirce SM, Saucerman JJ, Skalak TC. Systems analysis of small signaling modules relevant to eight human diseases. Annals of Biomedical Engineering. 39: 621-35. PMID 21132372 DOI: 10.1007/S10439-010-0208-Y |
0.582 |
|
| 2008 |
Yang J, Saucerman J. PKA Activity Compartmentation Requires Slow Nuclear Transport Kinetics in Cardiac Myocytes The Faseb Journal. 22: 312-312. DOI: 10.1096/Fasebj.22.2_Supplement.312 |
0.564 |
|
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