Jason H. Yang, PhD - Publications

Affiliations: 
2019- Microbiology, Biochemistry and Molecular Genetics Rutgers New Jersey Medical School 
Area:
systems biology, biomedical engineering, infectious disease
Website:
https://www.jasonyanglab.org

19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Ofori-Anyinam B, Hamblin M, Coldren ML, Li B, Mereddy G, Shaikh M, Shah A, Grady C, Ranu N, Lu S, Blainey PC, Ma S, Collins JJ, Yang JH. Catalase activity deficiency sensitizes multidrug-resistant Mycobacterium tuberculosis to the ATP synthase inhibitor bedaquiline. Nature Communications. 15: 9792. PMID 39537610 DOI: 10.1038/s41467-024-53933-8  0.474
2021 Lopatkin AJ, Yang JH. Digital Insights Into Nucleotide Metabolism and Antibiotic Treatment Failure. Frontiers in Digital Health. 3. PMID 34355212 DOI: 10.3389/fdgth.2021.583468  0.696
2021 Kim GL, Hooven TA, Norambuena J, Li B, Boyd JM, Yang JH, Parker D. Growth and Stress Tolerance Comprise Independent Metabolic Strategies Critical for Staphylococcus aureus Infection. Mbio. e0081421. PMID 34101490 DOI: 10.1128/mBio.00814-21  0.311
2021 Lopatkin AJ, Bening SC, Manson AL, Stokes JM, Kohanski MA, Badran AH, Earl AM, Cheney NJ, Yang JH, Collins JJ. Clinically relevant mutations in core metabolic genes confer antibiotic resistance. Science (New York, N.Y.). 371. PMID 33602825 DOI: 10.1126/science.aba0862  0.744
2019 Lopatkin AJ, Stokes JM, Zheng EJ, Yang JH, Takahashi MK, You L, Collins JJ. Bacterial metabolic state more accurately predicts antibiotic lethality than growth rate. Nature Microbiology. PMID 31451773 DOI: 10.1038/S41564-019-0536-0  0.727
2019 Yang JH, Wright SN, Hamblin M, McCloskey D, Alcantar MA, Schrübbers L, Lopatkin AJ, Satish S, Nili A, Palsson BO, Walker GC, Collins JJ. A White-Box Machine Learning Approach for Revealing Antibiotic Mechanisms of Action. Cell. PMID 31080069 DOI: 10.1016/J.Cell.2019.04.016  0.721
2017 Yang JH, Bhargava P, McCloskey D, Mao N, Palsson BO, Collins JJ. Antibiotic-Induced Changes to the Host Metabolic Environment Inhibit Drug Efficacy and Alter Immune Function. Cell Host & Microbe. 22: 757-765.e3. PMID 29199098 DOI: 10.1016/J.Chom.2017.10.020  0.639
2017 Yang JH, Bening SC, Collins JJ. Antibiotic efficacy-context matters. Current Opinion in Microbiology. 39: 73-80. PMID 29049930 DOI: 10.1016/J.Mib.2017.09.002  0.606
2017 Takahashi N, Gruber CC, Yang JH, Liu X, Braff D, Yashaswini CN, Bhubhanil S, Furuta Y, Andreescu S, Collins JJ, Walker GC. Lethality of MalE-LacZ hybrid protein shares mechanistic attributes with oxidative component of antibiotic lethality. Proceedings of the National Academy of Sciences of the United States of America. PMID 28794281 DOI: 10.1073/Pnas.1707466114  0.536
2017 Meylan S, Porter CB, Yang JH, Belenky P, Gutierrez A, Lobritz MA, Park J, Kim SH, Moskowitz SM, Collins JJ. Carbon Sources Tune Antibiotic Susceptibility in Pseudomonas aeruginosa via Tricarboxylic Acid Cycle Control. Cell Chemical Biology. PMID 28111098 DOI: 10.1016/J.Chembiol.2016.12.015  0.594
2015 Lobritz MA, Belenky P, Porter CB, Gutierrez A, Yang JH, Schwarz EG, Dwyer DJ, Khalil AS, Collins JJ. Antibiotic efficacy is linked to bacterial cellular respiration. Proceedings of the National Academy of Sciences of the United States of America. PMID 26100898 DOI: 10.1073/Pnas.1509743112  0.719
2014 Dwyer DJ, Belenky PA, Yang JH, MacDonald IC, Martell JD, Takahashi N, Chan CT, Lobritz MA, Braff D, Schwarz EG, Ye JD, Pati M, Vercruysse M, Ralifo PS, Allison KR, et al. Antibiotics induce redox-related physiological alterations as part of their lethality. Proceedings of the National Academy of Sciences of the United States of America. 111: E2100-9. PMID 24803433 DOI: 10.1073/Pnas.1401876111  0.73
2014 Yang JH, Polanowska-Grabowska RK, Smith JS, Shields CW, Saucerman JJ. PKA catalytic subunit compartmentation regulates contractile and hypertrophic responses to β-adrenergic signaling. Journal of Molecular and Cellular Cardiology. 66: 83-93. PMID 24225179 DOI: 10.1016/J.Yjmcc.2013.11.001  0.605
2013 Sample V, DiPilato LM, Yang JH, Ni Q, Saucerman JJ, Zhang J. Erratum: Corrigendum: Regulation of nuclear PKA revealed by spatiotemporal manipulation of cyclic AMP Nature Chemical Biology. 9: 406-406. DOI: 10.1038/Nchembio0613-406B  0.61
2012 Sample V, DiPilato LM, Yang JH, Ni Q, Saucerman JJ, Zhang J. Regulation of nuclear PKA revealed by spatiotemporal manipulation of cyclic AMP. Nature Chemical Biology. 8: 375-82. PMID 22366721 DOI: 10.1038/Nchembio.799  0.619
2012 Yang JH, Saucerman JJ. Phospholemman is a negative feed-forward regulator of Ca2+ in β-adrenergic signaling, accelerating β-adrenergic inotropy. Journal of Molecular and Cellular Cardiology. 52: 1048-55. PMID 22289214 DOI: 10.1016/J.Yjmcc.2011.12.015  0.589
2011 Yang JH, Saucerman JJ. Computational models reduce complexity and accelerate insight into cardiac signaling networks. Circulation Research. 108: 85-97. PMID 21212391 DOI: 10.1161/Circresaha.110.223602  0.586
2011 Benedict KF, Mac Gabhann F, Amanfu RK, Chavali AK, Gianchandani EP, Glaw LS, Oberhardt MA, Thorne BC, Yang JH, Papin JA, Peirce SM, Saucerman JJ, Skalak TC. Systems analysis of small signaling modules relevant to eight human diseases. Annals of Biomedical Engineering. 39: 621-35. PMID 21132372 DOI: 10.1007/S10439-010-0208-Y  0.582
2008 Yang J, Saucerman J. PKA Activity Compartmentation Requires Slow Nuclear Transport Kinetics in Cardiac Myocytes The Faseb Journal. 22: 312-312. DOI: 10.1096/Fasebj.22.2_Supplement.312  0.564
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