Raimond L. Winslow, Ph.D. - Publications

Affiliations: 
Biomedical Engineering Johns Hopkins University, Baltimore, MD 

151 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Wagle N, Morkos J, Liu J, Reith H, Greenstein J, Gong K, Gangan I, Pakhomov D, Hira S, Komogortsev OV, Newman-Toker DE, Winslow R, Zee DS, Otero-Millan J, Green KE. aEYE: A deep learning system for video nystagmus detection. Frontiers in Neurology. 13: 963968. PMID 36034311 DOI: 10.3389/fneur.2022.963968  0.472
2022 Ullah A, Hoang-Trong MT, Lederer WJ, Winslow RL, Jafri MS. Critical Requirements for the Initiation of a Cardiac Arrhythmia in Rat Ventricle: How Many Myocytes? Cells. 11. PMID 35741007 DOI: 10.3390/cells11121878  0.388
2021 Kim HB, Nguyen HT, Jin Q, Tamby S, Gelaf Romer T, Sung E, Liu R, Greenstein JL, Suarez JI, Storm C, Winslow RL, Stevens RD. Computational Signatures for Post-Cardiac Arrest Trajectory Prediction: Importance of Early Physiological Time Series. Anaesthesia, Critical Care & Pain Medicine. 101015. PMID 34968747 DOI: 10.1016/j.accpm.2021.101015  0.578
2021 Annapragada AV, Greenstein JL, Bose SN, Winters BD, Sarma SV, Winslow RL. SWIFT: A deep learning approach to prediction of hypoxemic events in critically-Ill patients using SpO2 waveform prediction. Plos Computational Biology. 17: e1009712. PMID 34932550 DOI: 10.1371/journal.pcbi.1009712  0.507
2021 Krachman JA, Patricoski JA, Le CT, Park J, Zhang R, Gong KD, Gangan I, Winslow RL, Greenstein JL, Fackler J, Sochet AA, Bergmann JP. Predicting Flow Rate Escalation for Pediatric Patients on High Flow Nasal Cannula Using Machine Learning. Frontiers in Pediatrics. 9: 734753. PMID 34820341 DOI: 10.3389/fped.2021.734753  0.501
2021 Jin Q, Greenstein JL, Winslow RL. Estimating ectopic beat probability with simplified statistical models that account for experimental uncertainty. Plos Computational Biology. 17: e1009536. PMID 34665814 DOI: 10.1371/journal.pcbi.1009536  0.631
2021 Bose SN, Greenstein JL, Fackler JC, Sarma SV, Winslow RL, Bembea MM. Early Prediction of Multiple Organ Dysfunction in the Pediatric Intensive Care Unit. Frontiers in Pediatrics. 9: 711104. PMID 34485201 DOI: 10.3389/fped.2021.711104  0.503
2021 Liu R, Greenstein JL, Fackler JC, Bergmann J, Bembea MM, Winslow RL. Prediction of Impending Septic Shock in Children With Sepsis. Critical Care Explorations. 3: e0442. PMID 34151278 DOI: 10.1097/CCE.0000000000000442  0.481
2021 Annapragada AV, Greenstein JL, Bose SN, Winters BD, Sarma SV, Winslow RL. SWIFT: A Deep Learning Approach to Prediction of Hypoxemic Events in Critically-Ill Patients Using SpO Waveform Prediction. Medrxiv : the Preprint Server For Health Sciences. PMID 33688661 DOI: 10.1101/2021.02.25.21252234  0.506
2020 Liu R, Greenstein JL, Fackler JC, Bembea MM, Winslow RL. Spectral clustering of risk score trajectories stratifies sepsis patients by clinical outcome and interventions received. Elife. 9. PMID 32959779 DOI: 10.7554/Elife.58142  0.534
2020 Jin Q, Greenstein JL, Winslow RL. Simplified Models Predict Cellular Arrhythmia Probabilities and Reveal the Impact of Experimental Parameter Uncertainty on the Predicted Distribution of Arrhythmic Events Biophysical Journal. 118: 409a. DOI: 10.1016/J.Bpj.2019.11.2316  0.566
2019 Liu R, Greenstein JL, Sarma SV, Winslow RL. Natural Language Processing of Clinical Notes for Improved Early Prediction of Septic Shock in the ICU. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2019: 6103-6108. PMID 31947237 DOI: 10.1109/EMBC.2019.8857819  0.494
2019 Liu R, Greenstein JL, Granite SJ, Fackler JC, Bembea MM, Sarma SV, Winslow RL. Data-driven discovery of a novel sepsis pre-shock state predicts impending septic shock in the ICU. Scientific Reports. 9: 6145. PMID 30992534 DOI: 10.1038/S41598-019-42637-5  0.545
2019 Chu L, Greenstein JL, Winslow RL. Na microdomains and sparks: Role in cardiac excitation-contraction coupling and arrhythmias in ankyrin-B deficiency. Journal of Molecular and Cellular Cardiology. PMID 30731085 DOI: 10.1016/J.Yjmcc.2019.02.001  0.673
2019 Limpitikul WB, Greenstein JL, Yue DT, Dick IE, Winslow RL. Probing L-Type Channel Calcium-Dependent Inactivation -- a Bilobal Model of Calmodulation Biophysical Journal. 116: 111a. DOI: 10.1016/J.Bpj.2018.11.631  0.585
2018 Limpitikul WB, Greenstein JL, Yue DT, Dick IE, Winslow RL. A bilobal model of Ca-dependent inactivation to probe the physiology of L-type Ca channels. The Journal of General Physiology. PMID 30470716 DOI: 10.1085/Jgp.201812115  0.697
2017 Walker MA, Gurev V, Rice JJ, Greenstein JL, Winslow RL. Estimating the probabilities of rare arrhythmic events in multiscale computational models of cardiac cells and tissue. Plos Computational Biology. 13: e1005783. PMID 29145393 DOI: 10.1371/Journal.Pcbi.1005783  0.698
2017 Zhao CY, Greenstein JL, Winslow RL. Mechanisms of the cyclic nucleotide cross-talk signaling network in cardiac L-type Calcium Channel regulation. Journal of Molecular and Cellular Cardiology. PMID 28365422 DOI: 10.1016/J.Yjmcc.2017.01.013  0.636
2016 Chu L, Greenstein JL, Winslow RL. Modeling Na(+)-Ca(2+) exchange in the heart: Allosteric activation, spatial localization, sparks and excitation-contraction coupling. Journal of Molecular and Cellular Cardiology. PMID 27377851 DOI: 10.1016/J.Yjmcc.2016.06.068  0.673
2016 Walker MA, Madduri R, Rodriguez A, Greenstein JL, Winslow RL. Models and Simulations as a Service: Exploring the Use of Galaxy for Delivering Computational Models. Biophysical Journal. 110: 1038-43. PMID 26958881 DOI: 10.1016/J.Bpj.2015.12.041  0.596
2016 Zhao CY, Greenstein JL, Winslow RL. Roles of phosphodiesterases in the regulation of the cardiac cyclic nucleotide cross-talk signaling network. Journal of Molecular and Cellular Cardiology. PMID 26773602 DOI: 10.1016/J.Yjmcc.2016.01.004  0.602
2016 Chu L, Greenstein JL, Winslow RL. Modeling the Role of NCX in the Regulation of Cardiomyocyte Microdomain Ca2+ Dynamics Biophysical Journal. 110: 99a. DOI: 10.1016/J.Bpj.2015.11.592  0.675
2016 Zhao CY, Greenstein JL, Winslow RL. Regulation of the Cardiac L-Type Calcium Channel by the Cyclic Nucleotide Cross-Talk Signaling Network Biophysical Journal. 110: 359a. DOI: 10.1016/J.Bpj.2015.11.1937  0.641
2015 Ardekani S, Jain S, Sanzi A, Corona-Villalobos CP, Abraham TP, Abraham MR, Zimmerman SL, Wu KC, Winslow RL, Miller MI, Younes L. Shape analysis of hypertrophic and hypertensive heart disease using MRI-based 3D surface models of left ventricular geometry. Medical Image Analysis. 29: 12-23. PMID 26766206 DOI: 10.1016/J.Media.2015.11.004  0.503
2015 Winslow RL, Walker MA, Greenstein JL. Modeling calcium regulation of contraction, energetics, signaling, and transcription in the cardiac myocyte. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. PMID 26562359 DOI: 10.1002/Wsbm.1322  0.669
2015 Walker MA, Kohl T, Lehnart SE, Greenstein JL, Lederer WJ, Winslow RL. On the Adjacency Matrix of RyR2 Cluster Structures. Plos Computational Biology. 11: e1004521. PMID 26545234 DOI: 10.1371/Journal.Pcbi.1004521  0.657
2015 Zhao CY, Greenstein JL, Winslow RL. Interaction between phosphodiesterases in the regulation of the cardiac β-adrenergic pathway. Journal of Molecular and Cellular Cardiology. 88: 29-38. PMID 26388264 DOI: 10.1016/J.Yjmcc.2015.09.011  0.628
2015 Foteinou PT, Greenstein JL, Winslow RL. Mechanistic Investigation of the Arrhythmogenic Role of Oxidized CaMKII in the Heart. Biophysical Journal. 109: 838-49. PMID 26287635 DOI: 10.1016/J.Bpj.2015.06.064  0.691
2015 Greenstein JL, Mehta T, Winslow RL. Effect of Hypertrophic Calcium Signals and Altered Excitation-Contraction Coupling on the Calcineurin-NFAT Pathway Biophysical Journal. 108: 420a. DOI: 10.1016/J.Bpj.2014.11.2298  0.691
2015 Chu L, Greenstein JL, Williams GS, Boyman L, Legenzov EA, Hagen BM, Lederer W, Winslow RL. Dynamics of Ca2+-Dependent Regulation of the Cardiac Na+/Ca2+ Exchanger Biophysical Journal. 108: 265a. DOI: 10.1016/J.Bpj.2014.11.1462  0.661
2015 Zhao CY, Greenstein JL, Winslow RL. Regulation of the Cardiac β-Adrenergic Pathway via Camp-Cgmp Competition Biophysical Journal. 108: 260a. DOI: 10.1016/J.Bpj.2014.11.1438  0.618
2015 Zhao CY, Greenstein JL, Winslow RL. Roles of Phosphodiesterases in Cyclic Nucleotide Cross-Talk in Cardiac Myocytes Biophysical Journal. 108: 260a. DOI: 10.1016/J.Bpj.2014.11.1437  0.609
2014 Walker MA, Williams GS, Kohl T, Lehnart SE, Jafri MS, Greenstein JL, Lederer WJ, Winslow RL. Superresolution modeling of calcium release in the heart. Biophysical Journal. 107: 3018-29. PMID 25517166 DOI: 10.1016/J.Bpj.2014.11.003  0.67
2014 Greenstein JL, Foteinou PT, Hashambhoy-Ramsay YL, Winslow RL. Modeling CaMKII-mediated regulation of L-type Ca(2+) channels and ryanodine receptors in the heart. Frontiers in Pharmacology. 5: 60. PMID 24772082 DOI: 10.3389/Fphar.2014.00060  0.69
2014 Winslow RL. Systems biology approaches to understanding the cause and treatment of heart, lung, blood, and sleep disorders. Frontiers in Physiology. 5: 107. PMID 24734021 DOI: 10.3389/Fphys.2014.00107  0.337
2014 Ullah A, Hoang Trong MT, Williams GS, Winslow RL, Lederer WJ, Jafri MS. Critical Requirements for the Initiation of a Cardiac Arrhythmia in Heart: Cell Number Biophysical Journal. 106: 431a. DOI: 10.1016/J.Bpj.2013.11.2427  0.472
2014 Walker MA, Williams GS, Kohl T, Jafri S, Lehnart SE, Greenstein JL, Lederer W, Winslow RL. Super-Resolution Modeling of Calcium Release in Heart Biophysical Journal. 106: 318a. DOI: 10.1016/j.bpj.2013.11.1839  0.565
2013 Gauthier LD, Greenstein JL, O'Rourke B, Winslow RL. An integrated mitochondrial ROS production and scavenging model: implications for heart failure. Biophysical Journal. 105: 2832-42. PMID 24359755 DOI: 10.1016/J.Bpj.2013.11.007  0.813
2013 Gauthier LD, Greenstein JL, Cortassa S, O'Rourke B, Winslow RL. A computational model of reactive oxygen species and redox balance in cardiac mitochondria. Biophysical Journal. 105: 1045-56. PMID 23972856 DOI: 10.1016/J.Bpj.2013.07.006  0.784
2013 Winslow RL, Greenstein JL. Extinguishing the sparks. Biophysical Journal. 104: 2115-7. PMID 23708349 DOI: 10.1016/J.Bpj.2013.04.010  0.647
2013 Aiba T, Barth AS, Hesketh GG, Hashambhoy YL, Chakir K, Tunin RS, Greenstein JL, Winslow RL, Kass DA, Tomaselli GF. Cardiac resynchronization therapy improves altered Na channel gating in canine model of dyssynchronous heart failure. Circulation. Arrhythmia and Electrophysiology. 6: 546-54. PMID 23650309 DOI: 10.1161/Circep.113.000400  0.809
2013 Kembro JM, Aon MA, Winslow RL, O'Rourke B, Cortassa S. Integrating mitochondrial energetics, redox and ROS metabolic networks: a two-compartment model. Biophysical Journal. 104: 332-43. PMID 23442855 DOI: 10.1016/J.Bpj.2012.11.3808  0.329
2013 Gauthier LD, Cortassa S, Greenstein JL, Winslow RL. Mechanistic Electron Transport Chain Model Explains ROS Production in Different Respiratory Modes Biophysical Journal. 104: 304a-305a. DOI: 10.1016/J.Bpj.2012.11.1694  0.782
2013 Wei A, Liu T, Winslow RL, O'Rourke B. Regulation of Mitochondrial Ca2+ Dynamics by Inorganic Phosphate Biophysical Journal. 104: 301a-302a. DOI: 10.1016/J.Bpj.2012.11.1679  0.369
2012 Winslow RL, Trayanova N, Geman D, Miller MI. Computational medicine: translating models to clinical care. Science Translational Medicine. 4: 158rv11. PMID 23115356 DOI: 10.1126/Scitranslmed.3003528  0.478
2012 Gauthier LD, Greenstein JL, Winslow RL. Toward an integrative computational model of the Guinea pig cardiac myocyte. Frontiers in Physiology. 3: 244. PMID 22783206 DOI: 10.3389/Fphys.2012.00244  0.83
2012 Wei AC, Liu T, Winslow RL, O'Rourke B. Dynamics of matrix-free Ca2+ in cardiac mitochondria: two components of Ca2+ uptake and role of phosphate buffering. The Journal of General Physiology. 139: 465-78. PMID 22641641 DOI: 10.1085/Jgp.201210784  0.409
2012 Steinert-Threlkeld S, Ardekani S, Mejino JL, Detwiler LT, Brinkley JF, Halle M, Kikinis R, Winslow RL, Miller MI, Ratnanather JT. Ontological labels for automated location of anatomical shape differences. Journal of Biomedical Informatics. 45: 522-7. PMID 22490168 DOI: 10.1016/J.Jbi.2012.02.013  0.486
2012 Gauthier LD, Greenstein JL, Winslow RL. Local Control Model Illustrates How Action Potential Morphology Affects Ca2+ Release Biophysical Journal. 102: 553a. DOI: 10.1016/J.Bpj.2011.11.3016  0.816
2011 Hashambhoy YL, Winslow RL, Greenstein JL. CaMKII-dependent activation of late INa contributes to cellular arrhythmia in a model of the cardiac myocyte. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2011: 4665-8. PMID 22255378 DOI: 10.1109/IEMBS.2011.6091155  0.82
2011 Quinn TA, Granite S, Allessie MA, Antzelevitch C, Bollensdorff C, Bub G, Burton RA, Cerbai E, Chen PS, Delmar M, Difrancesco D, Earm YE, Efimov IR, Egger M, Entcheva E, ... ... Winslow RL, et al. Minimum Information about a Cardiac Electrophysiology Experiment (MICEE): standardised reporting for model reproducibility, interoperability, and data sharing. Progress in Biophysics and Molecular Biology. 107: 4-10. PMID 21745496 DOI: 10.1016/J.Pbiomolbio.2011.07.001  0.359
2011 Winslow RL, Greenstein JL. Cardiac myocytes and local signaling in nano-domains. Progress in Biophysics and Molecular Biology. 107: 48-59. PMID 21718716 DOI: 10.1016/J.Pbiomolbio.2011.06.005  0.654
2011 Wei AC, Aon MA, O'Rourke B, Winslow RL, Cortassa S. Mitochondrial energetics, pH regulation, and ion dynamics: a computational-experimental approach. Biophysical Journal. 100: 2894-903. PMID 21689522 DOI: 10.1016/J.Bpj.2011.05.027  0.338
2011 Anderson T, Wulfkuhle J, Petricoin E, Winslow RL. High resolution mapping of the cardiac transmural proteome using reverse phase protein microarrays. Molecular & Cellular Proteomics : McP. 10: M111.008037. PMID 21490165 DOI: 10.1074/Mcp.M111.008037  0.573
2011 Wei AC, Liu T, Cortassa S, Winslow RL, O'Rourke B. Mitochondrial Ca2+ influx and efflux rates in guinea pig cardiac mitochondria: low and high affinity effects of cyclosporine A. Biochimica Et Biophysica Acta. 1813: 1373-81. PMID 21362444 DOI: 10.1016/J.Bbamcr.2011.02.012  0.4
2011 Greenstein JL, Winslow RL. Integrative systems models of cardiac excitation-contraction coupling. Circulation Research. 108: 70-84. PMID 21212390 DOI: 10.1161/Circresaha.110.223578  0.69
2011 Winslow RL, Cortassa S, O'Rourke B, Hashambhoy YL, Rice JJ, Greenstein JL. Integrative modeling of the cardiac ventricular myocyte. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 3: 392-413. PMID 20865780 DOI: 10.1002/Wsbm.122  0.822
2011 Winslow RL. Grand challenges in computational physiology and medicine Frontiers in Physiology. 2. DOI: 10.3389/Fphys.2011.00079  0.363
2011 Jafri MS, Lederer WJ, Williams GS, Greenstein JL, Winslow RL. Modeling the Mechanisms of Calcium-Mediated Cardiac Arrhythmias Biophysical Journal. 100: 556a-557a. DOI: 10.1016/J.Bpj.2010.12.3236  0.619
2011 Wei A, Liu T, Cortassa S, Winslow R, O'Rourke B. Sodium Effects on Calcium Dynamics in Mitochondrial ion Circuits Biophysical Journal. 100: 461a. DOI: 10.1016/J.Bpj.2010.12.2710  0.405
2011 Gauthier LD, Greenstein JL, Winslow RL. The Role of Reactive Oxygen Species in Contractile Dysfunction Following Ischemia/Reperfusion Biophysical Journal. 100: 292a. DOI: 10.1016/J.Bpj.2010.12.1796  0.813
2010 Hashambhoy YL, Greenstein JL, Winslow RL. Role of CaMKII in RyR leak, EC coupling and action potential duration: a computational model. Journal of Molecular and Cellular Cardiology. 49: 617-24. PMID 20655925 DOI: 10.1016/J.Yjmcc.2010.07.011  0.821
2010 Zhou L, Aon MA, Almas T, Cortassa S, Winslow RL, O'Rourke B. A reaction-diffusion model of ROS-induced ROS release in a mitochondrial network. Plos Computational Biology. 6: e1000657. PMID 20126535 DOI: 10.1371/Journal.Pcbi.1000657  0.783
2010 Doyle LA, Greenstein JL, Winslow RL. Multi-Scale, Integrative Model Development using High-Performance Computer Architectures Biophysical Journal. 98: 574a. DOI: 10.1016/J.Bpj.2009.12.3120  0.646
2010 Hashambhoy YL, Winslow RL, Greenstein JL. CamkII Phosphorylation of RyRs: a Mechanistic Mathematical Model Biophysical Journal. 98: 548a-549a. DOI: 10.1016/J.Bpj.2009.12.2973  0.817
2010 Zhou L, Wei A, Liu T, Cortassa S, Winslow R, O'Rourke B. Simulation of the Impact of Elevated Cytosolic Na+ on Ca2+ Handling, Mitochondrial Energetics and Cellular Electrophysiology in Guinea Pig Myocytes Biophysical Journal. 98: 411a. DOI: 10.1016/J.Bpj.2009.12.2219  0.431
2009 Ardekani S, Weiss RG, Lardo AC, Miller MI, Winslow RL, Younes L. Cardiac Motion Analysis in Ischemic and Non-Ischemic Cardiomyopathy Using Parallel Transport. Proceedings / Ieee International Symposium On Biomedical Imaging: From Nano to Macro. Ieee International Symposium On Biomedical Imaging. 899. PMID 20119497 DOI: 10.1109/ISBI.2009.5193198  0.4
2009 Anderson T, Wulfkuhle J, Liotta L, Winslow RL, Petricoin E. Improved reproducibility of reverse-phase protein microarrays using array microenvironment normalization. Proteomics. 9: 5562-6. PMID 19834915 DOI: 10.1002/Pmic.200900505  0.483
2009 Zhou L, Cortassa S, Wei AC, Aon MA, Winslow RL, O'Rourke B. Modeling cardiac action potential shortening driven by oxidative stress-induced mitochondrial oscillations in guinea pig cardiomyocytes. Biophysical Journal. 97: 1843-52. PMID 19804714 DOI: 10.1016/J.Bpj.2009.07.029  0.387
2009 Cortassa S, O'Rourke B, Winslow RL, Aon MA. Control and regulation of integrated mitochondrial function in metabolic and transport networks. International Journal of Molecular Sciences. 10: 1500-13. PMID 19468321 DOI: 10.3390/Ijms10041500  0.365
2009 Chen CS, Sullivan S, Anderson T, Tan AC, Alex PJ, Brant SR, Cuffari C, Bayless TM, Talor MV, Burek CL, Wang H, Li R, Datta LW, Wu Y, Winslow RL, et al. Identification of novel serological biomarkers for inflammatory bowel disease using Escherichia coli proteome chip. Molecular & Cellular Proteomics : McP. 8: 1765-76. PMID 19357087 DOI: 10.1074/Mcp.M800593-Mcp200  0.466
2009 Ardekani S, Weiss RG, Lardo AC, George RT, Lima JA, Wu KC, Miller MI, Winslow RL, Younes L. Computational method for identifying and quantifying shape features of human left ventricular remodeling. Annals of Biomedical Engineering. 37: 1043-54. PMID 19322659 DOI: 10.1007/S10439-009-9677-2  0.515
2009 Cortassa S, O'Rourke B, Winslow RL, Aon MA. Control and regulation of mitochondrial energetics in an integrated model of cardiomyocyte function. Biophysical Journal. 96: 2466-78. PMID 19289071 DOI: 10.1016/J.Bpj.2008.12.3893  0.37
2009 Hashambhoy YL, Winslow RL, Greenstein JL. CaMKII-induced shift in modal gating explains L-type Ca(2+) current facilitation: a modeling study. Biophysical Journal. 96: 1770-85. PMID 19254537 DOI: 10.1016/J.Bpj.2008.11.055  0.813
2009 Hashambhoy YL, Winslow RL, Greenstein JL. A Mechanistic, Minimal Model of Ca2+/Calmodulin Dependent Kinase II Signaling in the Cardiac Myocyte Biophysical Journal. 96: 540a. DOI: 10.1016/J.Bpj.2008.12.2789  0.829
2009 Doyle LA, Greenstein JL, Winslow RL. Modeling cAMP-cGMP Crosstalk in the Cardiac Myocyte Biophysical Journal. 96: 304a. DOI: 10.1016/J.Bpj.2008.12.1514  0.625
2009 Wei A, Aon MA, O'Rourke B, Winslow RL, Cortassa S. Mitochondrial Energetics During Transients Following Substrate And Ca2+ Additions. Modeling And Experimental Studies Biophysical Journal. 96: 243a-244a. DOI: 10.1016/J.Bpj.2008.12.1199  0.424
2008 Younes L, Qiu A, Winslow RL, Miller MI. Transport of Relational Structures in Groups of Diffeomorphisms. Journal of Mathematical Imaging and Vision. 32: 41-56. PMID 19809583 DOI: 10.1007/S10851-008-0074-5  0.421
2008 Gao Z, Barth AS, DiSilvestre D, Akar FG, Tian Y, Tanskanen A, Kass DA, Winslow RL, Tomaselli GF. Key pathways associated with heart failure development revealed by gene networks correlated with cardiac remodeling. Physiological Genomics. 35: 222-30. PMID 18780759 DOI: 10.1152/Physiolgenomics.00100.2007  0.357
2008 Plank G, Zhou L, Greenstein JL, Cortassa S, Winslow RL, O'Rourke B, Trayanova NA. From mitochondrial ion channels to arrhythmias in the heart: computational techniques to bridge the spatio-temporal scales. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 366: 3381-409. PMID 18603526 DOI: 10.1098/Rsta.2008.0112  0.65
2007 Bober MB, Winslow R. Developing computational resources in cardiac gene expression Methods in Molecular Biology. 366: 253-263. PMID 17568129 DOI: 10.1007/978-1-59745-030-0_14  0.312
2007 Anderson TJ, Tchernyshyov I, Diez R, Cole RN, Geman D, Dang CV, Winslow RL. Discovering robust protein biomarkers for disease from relative expression reversals in 2-D DIGE data. Proteomics. 7: 1197-207. PMID 17366473 DOI: 10.1002/Pmic.200600374  0.488
2007 Tanskanen AJ, Greenstein JL, Chen A, Sun SX, Winslow RL. Protein geometry and placement in the cardiac dyad influence macroscopic properties of calcium-induced calcium release. Biophysical Journal. 92: 3379-96. PMID 17325016 DOI: 10.1529/Biophysj.106.089425  0.661
2006 Cao Y, Miller MI, Mori S, Winslow RL, Younes L. Diffeomorphic Matching of Diffusion Tensor Images. Proceedings / Cvpr, Ieee Computer Society Conference On Computer Vision and Pattern Recognition. Ieee Computer Society Conference On Computer Vision and Pattern Recognition. 2006: 67. PMID 20711423 DOI: 10.1109/CVPRW.2006.65  0.345
2006 Winslow RL, Tanskanen A, Chen M, Greenstein JL. Multiscale modeling of calcium signaling in the cardiac dyad. Annals of the New York Academy of Sciences. 1080: 362-75. PMID 17132795 DOI: 10.1196/Annals.1380.027  0.679
2006 Cortassa S, Aon MA, O'Rourke B, Jacques R, Tseng HJ, Marbán E, Winslow RL. A computational model integrating electrophysiology, contraction, and mitochondrial bioenergetics in the ventricular myocyte. Biophysical Journal. 91: 1564-89. PMID 16679365 DOI: 10.1529/Biophysj.105.076174  0.474
2006 Helm PA, Younes L, Beg MF, Ennis DB, Leclercq C, Faris OP, McVeigh E, Kass D, Miller MI, Winslow RL. Evidence of structural remodeling in the dyssynchronous failing heart. Circulation Research. 98: 125-32. PMID 16339482 DOI: 10.1161/01.Res.0000199396.30688.Eb  0.681
2006 Hinch R, Greenstein JL, Winslow RL. Multi-scale models of local control of calcium induced calcium release. Progress in Biophysics and Molecular Biology. 90: 136-50. PMID 16321427 DOI: 10.1016/J.Pbiomolbio.2005.05.014  0.647
2006 Gao Z, Xu H, DiSilvestre D, Halperin VL, Tunin R, Tian Y, Yu W, Winslow RL, Tomaselli GF. Transcriptomic profiling of the canine tachycardia-induced heart failure model: global comparison to human and murine heart failure. Journal of Molecular and Cellular Cardiology. 40: 76-86. PMID 16236311 DOI: 10.1016/J.Yjmcc.2005.08.002  0.365
2006 Greenstein JL, Hinch R, Winslow RL. Mechanisms of excitation-contraction coupling in an integrative model of the cardiac ventricular myocyte. Biophysical Journal. 90: 77-91. PMID 16214852 DOI: 10.1529/Biophysj.105.065169  0.693
2006 Tanskanen AJ, Winslow RL. Integrative structurally detailed model of calcium dynamics in the cardiac diad Multiscale Modeling and Simulation. 5: 1280-1296. DOI: 10.1137/05064549X  0.498
2005 Cao Y, Miller MI, Winslow RL, Younes L. Large deformation diffeomorphic metric mapping of vector fields. Ieee Transactions On Medical Imaging. 24: 1216-30. PMID 16156359  0.369
2005 Helm PA, Tseng HJ, Younes L, McVeigh ER, Winslow RL. Ex vivo 3D diffusion tensor imaging and quantification of cardiac laminar structure. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 54: 850-9. PMID 16149057 DOI: 10.1002/Mrm.20622  0.605
2005 Helm P, Beg MF, Miller MI, Winslow RL. Measuring and mapping cardiac fiber and laminar architecture using diffusion tensor MR imaging. Annals of the New York Academy of Sciences. 1047: 296-307. PMID 16093505 DOI: 10.1196/Annals.1341.026  0.692
2005 Winslow RL, Cortassa S, Greenstein JL. Using models of the myocyte for functional interpretation of cardiac proteomic data. The Journal of Physiology. 563: 73-81. PMID 15611013 DOI: 10.1113/Jphysiol.2004.080457  0.68
2005 Tanskanen AJ, Greenstein JL, O'Rourke B, Winslow RL. The role of stochastic and modal gating of cardiac L-type Ca2+ channels on early after-depolarizations. Biophysical Journal. 88: 85-95. PMID 15501946 DOI: 10.1529/Biophysj.104.051508  0.662
2005 Winslow RL, Hinch R, Greenstein JL. Mechanisms and models of cardiac excitation-contraction coupling Lecture Notes in Mathematics. 1867: 97-131. DOI: 10.1007/11406501_4  0.589
2004 Winslow RL, Greenstein JL. The ongoing journey to understand heart function through integrative modeling. Circulation Research. 95: 1135-6. PMID 15591234 DOI: 10.1161/01.Res.0000151330.81518.73  0.691
2004 Beg MF, Helm PA, McVeigh E, Miller MI, Winslow RL. Computational cardiac anatomy using MRI. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 52: 1167-74. PMID 15508155 DOI: 10.1002/Mrm.20255  0.695
2004 Hinch R, Greenstein JL, Tanskanen AJ, Xu L, Winslow RL. A simplified local control model of calcium-induced calcium release in cardiac ventricular myocytes. Biophysical Journal. 87: 3723-36. PMID 15465866 DOI: 10.1529/Biophysj.104.049973  0.678
2004 Cortassa S, Aon MA, Winslow RL, O'Rourke B. A mitochondrial oscillator dependent on reactive oxygen species. Biophysical Journal. 87: 2060-73. PMID 15345581 DOI: 10.1529/Biophysj.104.041749  0.333
2004 Iyer V, Mazhari R, Winslow RL. A computational model of the human left-ventricular epicardial myocyte. Biophysical Journal. 87: 1507-25. PMID 15345532 DOI: 10.1529/Biophysj.104.043299  0.407
2004 Greenstein JL, Tanskanen AJ, Winslow RL. Modeling the actions of beta-adrenergic signaling on excitation--contraction coupling processes. Annals of the New York Academy of Sciences. 1015: 16-27. PMID 15201146 DOI: 10.1196/Annals.1302.002  0.643
2004 Yung CK, Halperin VL, Tomaselli GF, Winslow RL. Gene expression profiles in end-stage human idiopathic dilated cardiomyopathy: altered expression of apoptotic and cytoskeletal genes. Genomics. 83: 281-97. PMID 14706457 DOI: 10.1016/J.Ygeno.2003.08.007  0.68
2003 Dos Remedios CG, Liew CC, Allen PD, Winslow RL, Van Eyk JE, Dunn MJ. Genomics, proteomics and bioinformatics of human heart failure. Journal of Muscle Research and Cell Motility. 24: 251-60. PMID 14620738 DOI: 10.1023/A:1025433721505  0.327
2003 Armoundas AA, Hobai IA, Tomaselli GF, Winslow RL, O'Rourke B. Role of sodium-calcium exchanger in modulating the action potential of ventricular myocytes from normal and failing hearts. Circulation Research. 93: 46-53. PMID 12805237 DOI: 10.1161/01.Res.0000080932.98903.D8  0.417
2003 Cortassa S, Aon MA, Marbán E, Winslow RL, O'Rourke B. An integrated model of cardiac mitochondrial energy metabolism and calcium dynamics. Biophysical Journal. 84: 2734-55. PMID 12668482 DOI: 10.1016/S0006-3495(03)75079-6  0.445
2002 Winslow RL, Helm P, Baumgartner W, Peddi S, Ratnanather T, McVeigh E, Miller MI. Imaging-based integrative models of the heart: closing the loop between experiment and simulation. Novartis Foundation Symposium. 247: 129-41; discussion 1. PMID 12539953 DOI: 10.1002/0470857897.Ch11  0.699
2002 Greenstein JL, Winslow RL. An integrative model of the cardiac ventricular myocyte incorporating local control of Ca2+ release. Biophysical Journal. 83: 2918-45. PMID 12496068 DOI: 10.1016/S0006-3495(02)75301-0  0.677
2002 Bober M, Wiehe K, Yung C, Suzek TO, Lin M, Baumgartner W, Winslow R. CaGE: Cardiac gene expression knowledgebase Bioinformatics. 18: 1013-1014. PMID 12117801 DOI: 10.1093/Bioinformatics/18.7.1013  0.69
2002 Mazhari R, Nuss HB, Armoundas AA, Winslow RL, Marbán E. Ectopic expression of KCNE3 accelerates cardiac repolarization and abbreviates the QT interval. The Journal of Clinical Investigation. 109: 1083-90. PMID 11956246 DOI: 10.1172/Jci15062  0.325
2001 Mazhari R, Greenstein JL, Winslow RL, Marbán E, Nuss HB. Molecular interactions between two long-QT syndrome gene products, HERG and KCNE2, rationalized by in vitro and in silico analysis. Circulation Research. 89: 33-8. PMID 11440975 DOI: 10.1161/Hh1301.093633  0.589
2001 Winslow RL, Scollan DF, Greenstein JL, Yung CK, Baumgartner W. J, Bhanot G, Gresh DL, Rogowitz BE. Mapping, modeling, and visual exploration of structure-function relationships in the heart Ibm Systems Journal. 40: 342-359. DOI: 10.1147/Sj.402.0342  0.781
2001 Winslow RL, Scollan DF, Greenstein JL, Yung CK, Baumgartner W, Bhanot G, Gresh DL, Rogowitz BE. Mapping, modeling, and visual exploration of structure-function relationships in the heart Ibm Systems Journal. 40: 342-359. DOI: 10.1147/sj.402.0342  0.775
2001 Winslow RL, Greenstein JL, Tomaselli GF, O'Rourke B. Computational models of the failing myocyte: Relating altered gene expression to cellular function Philosophical Transactions of the Royal Society a: Mathematical, Physical and Engineering Sciences. 359: 1187-1200. DOI: 10.1098/Rsta.2001.0825  0.683
2000 Winslow RL, Scollan DF, Holmes A, Yung CK, Zhang J, Jafri MS. Electrophysiological modeling of cardiac ventricular function: from cell to organ. Annual Review of Biomedical Engineering. 2: 119-55. PMID 11701509 DOI: 10.1146/Annurev.Bioeng.2.1.119  0.817
2000 Scollan DF, Holmes A, Zhang J, Winslow RL. Reconstruction of cardiac ventricular geometry and fiber orientation using magnetic resonance imaging. Annals of Biomedical Engineering. 28: 934-44. PMID 11144678 DOI: 10.1114/1.1312188  0.784
2000 Greenstein JL, Wu R, Po S, Tomaselli GF, Winslow RL. Role of the calcium-independent transient outward current I(to1) in shaping action potential morphology and duration. Circulation Research. 87: 1026-33. PMID 11090548 DOI: 10.1161/01.Res.87.11.1026  0.636
2000 Holmes AA, Scollan DF, Winslow RL. Direct histological validation of diffusion tensor MRI in formaldehyde-fixed myocardium. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 44: 157-61. PMID 10893534 DOI: 10.1002/1522-2594(200007)44:1<157::Aid-Mrm22>3.0.Co;2-F  0.781
2000 Rice JJ, Jafri MS, Winslow RL. Modeling short-term interval-force relations in cardiac muscle. American Journal of Physiology. Heart and Circulatory Physiology. 278: H913-31. PMID 10710361 DOI: 10.1152/Ajpheart.2000.278.3.H913  0.445
2000 Kohl P, Noble D, Winslow RL, Hunter PJ. Computational modelling of biological systems: tools and visions Philosophical Transactions of the Royal Society of London. Series a: Mathematical, Physical and Engineering Sciences. 358: 579-610. DOI: 10.1098/Rsta.2000.0547  0.357
2000 Gresh DL, Rogowitz BE, Winslow RL, Scollan DF, Yung CK. WEAVE: A system for visually linking 3-D and statistical visualizations, applied to cardiac simulation and measurement data Proceedings of the Ieee Visualization Conference. 489-492+597.  0.766
2000 Winslow R, Greenstein J, Delmar P. Modulation of the cardiac ventricular myocyte action potential by intracellular calcium Annals of Biomedical Engineering. 28: S-30.  0.575
1999 Rice JJ, Jafri MS, Winslow RL. Modeling gain and gradedness of Ca2+ release in the functional unit of the cardiac diadic space. Biophysical Journal. 77: 1871-84. PMID 10512809 DOI: 10.1016/S0006-3495(99)77030-X  0.442
1999 Steinmetz PN, Winslow RL. Optimal detection of flash intensity differences using rod photocurrent observations. Neural Computation. 11: 1097-111. PMID 10418159 DOI: 10.1162/089976699300016368  0.646
1999 Rice JJ, Winslow RL, Hunter WC. Comparison of putative cooperative mechanisms in cardiac muscle: length dependence and dynamic responses. The American Journal of Physiology. 276: H1734-54. PMID 10330260 DOI: 10.1152/Ajpheart.1999.276.5.H1734  0.415
1999 Irvine LA, Jafri MS, Winslow RL. Cardiac sodium channel Markov model with temperature dependence and recovery from inactivation. Biophysical Journal. 76: 1868-85. PMID 10096885 DOI: 10.1016/S0006-3495(99)77346-7  0.732
1999 Winslow RL, Rice J, Jafri S, Marbán E, O'Rourke B. Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure, II: model studies. Circulation Research. 84: 571-86. PMID 10082479 DOI: 10.1161/01.Res.84.5.571  0.482
1998 Rice JJ, Jafri MS, Winslow RL. Modeling short-term interval-force relations in cardiac muscle. Annals of the New York Academy of Sciences. 853: 345-9. PMID 10603976 DOI: 10.1111/J.1749-6632.1998.Tb08296.X  0.309
1998 Scollan DF, Holmes A, Winslow R, Forder J. Histological validation of myocardial microstructure obtained from diffusion tensor magnetic resonance imaging. The American Journal of Physiology. 275: H2308-18. PMID 9843833 DOI: 10.1152/Ajpheart.1998.275.6.H2308  0.777
1998 Winslow RL, Rice J, Jafri S. Modeling the cellular basis of altered excitation-contraction coupling in heart failure. Progress in Biophysics and Molecular Biology. 69: 497-514. PMID 9785953 DOI: 10.1016/S0079-6107(98)00022-4  0.325
1998 Zhang H, Winslow R, Holden AV. Re-entrant Excitation Initiated in Models of Inhomogeneous Atrial Tissue Journal of Theoretical Biology. 191: 279-287. PMID 9631568 DOI: 10.1006/Jtbi.1997.0598  0.302
1998 Rice JJ, Winslow RL, Dekanski J, McVeigh E. Model studies of the role of mechano-sensitive currents in the generation of cardiac arrhythmias. Journal of Theoretical Biology. 190: 295-312. PMID 9533866 DOI: 10.1006/Jtbi.1997.0538  0.425
1998 Jafri MS, Rice JJ, Winslow RL. Cardiac Ca2+ dynamics: the roles of ryanodine receptor adaptation and sarcoplasmic reticulum load. Biophysical Journal. 74: 1149-68. PMID 9512016 DOI: 10.1016/S0006-3495(98)77832-4  0.458
1996 Noble D, LeGuennec JY, Winslow R. Functional roles of sodium-calcium exchange in normal and abnormal cardiac rhythm. Annals of the New York Academy of Sciences. 779: 480-8. PMID 8659864 DOI: 10.1111/J.1749-6632.1996.Tb44822.X  0.339
1996 Irvine LA, Winslow RL. Numerical studies of use-dependent block of cardiac sodium channels by quinidine on spiral wave reentry Computers in Cardiology. 613-616.  0.681
1995 Winslow RL, Cai D, Varghese A, Lai YC. Generation and propagation of normal and abnormal pacemaker activity in network models of cardiac sinus node and atrium Chaos, Solitons and Fractals. 5: 491-512. DOI: 10.1016/0960-0779(93)E0038-D  0.338
1994 Lai YC, Winslow RL, Sachs MB. A model of selective processing of auditory-nerve inputs by stellate cells of the antero-ventral cochlear nucleus. Journal of Computational Neuroscience. 1: 167-94. PMID 8792230 DOI: 10.1007/Bf00961733  0.626
1994 Varghese A, Winslow RL. Dynamics of abnormal pacemaking activity in cardiac Purkinje fibers. Journal of Theoretical Biology. 168: 407-20. PMID 8072299 DOI: 10.1006/Jtbi.1994.1121  0.351
1994 Cai D, Winslow RL, Noble D. Effects of gap junction conductance on dynamics of sinoatrial node cells: two-cell and large-scale network models. Ieee Transactions On Bio-Medical Engineering. 41: 217-31. PMID 8045574 DOI: 10.1109/10.284940  0.313
1994 Lai Y, Winslow RL, Sachs MB. The Functional Role of Excitatory and Inhibitory Interactions in Chopper Cells of the Anteroventral Cochlear Nucleus Neural Computation. 6: 1127-1140. DOI: 10.1162/Neco.1994.6.6.1127  0.618
1993 Cai D, Lai YC, Winslow RL. Complex dynamics in coupled cardiac pacemaker cells. Physical Review Letters. 71: 2501-2504. PMID 10054696 DOI: 10.1103/Physrevlett.71.2501  0.36
1993 Winslow RL, Varghese A, Noble D, Adlakha C, Hoythya A. Generation and propagation of ectopic beats induced by spatially localized Na-K pump inhibition in atrial network models. Proceedings. Biological Sciences / the Royal Society. 254: 55-61. PMID 8265676 DOI: 10.1098/Rspb.1993.0126  0.322
1993 Winslow RL, Kimball AL, Varghese A, Noble D. Simulating cardiac sinus and atrial network dynamics on the connection machine Physica D: Nonlinear Phenomena. 64: 281-298. DOI: 10.1016/0167-2789(93)90260-8  0.341
1993 Varghese A, Winslow RL. Dynamics of the calcium subsystem in cardiac Purkinje fibers Physica D: Nonlinear Phenomena. 68: 364-386. DOI: 10.1016/0167-2789(93)90131-J  0.352
1993 Noble D, Denyer JC, Brown HF, Winslow R, Kimball A. Cardiac pacemaker activity : from single cells to modelling the heart Developments in Cardiovascular Medicine. 140: 93-110. DOI: 10.1007/978-1-4615-3090-9_8  0.402
1990 Winslow RL, Ma S. Bifurcation analysis of nonlinear retinal horizontal cell models. II. Network properties. Journal of Neurophysiology. 64: 248-61. PMID 2388069 DOI: 10.1152/Jn.1990.64.1.248  0.367
1989 Sachs MB, Winslow RL, Sokolowski BH. A computational model for rate-level functions from cat auditory-nerve fibers. Hearing Research. 41: 61-9. PMID 2793615 DOI: 10.1016/0378-5955(89)90179-2  0.77
1989 Winslow RL. Bifurcation analysis of nonlinear retinal horizontal cell models. I. Properties of isolated cells. Journal of Neurophysiology. 62: 738-49. PMID 2769357 DOI: 10.1152/Jn.1989.62.3.738  0.411
1988 Winslow RL, Sachs MB. Single-tone intensity discrimination based on auditory-nerve rate responses in backgrounds of quiet, noise, and with stimulation of the crossed olivocochlear bundle. Hearing Research. 35: 165-89. PMID 3198509 DOI: 10.1016/0378-5955(88)90116-5  0.616
1987 Winslow RL, Sachs MB. Effect of electrical stimulation of the crossed olivocochlear bundle on auditory nerve response to tones in noise. Journal of Neurophysiology. 57: 1002-21. PMID 3585452 DOI: 10.1152/Jn.1987.57.4.1002  0.606
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