Jin Zhang, Ph.D. - Publications

Affiliations: 
Pharmacology Johns Hopkins University, Baltimore, MD 
Area:
FRET, cell signaling

97 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Zhang JF, Mehta S, Zhang J. Signaling Microdomains in the Spotlight: Visualizing Compartmentalized Signaling Using Genetically Encoded Fluorescent Biosensors. Annual Review of Pharmacology and Toxicology. 61: 587-608. PMID 33411579 DOI: 10.1146/annurev-pharmtox-010617-053137  0.64
2020 Tenner B, Getz M, Ross B, Ohadi D, Bohrer CH, Greenwald E, Mehta S, Xiao J, Rangamani P, Zhang J. Spatially compartmentalized phase regulation of a Ca-cAMP-PKA oscillatory circuit. Elife. 9. PMID 33201801 DOI: 10.7554/eLife.55013  0.64
2020 Zhang JF, Liu B, Hong I, Mo A, Roth RH, Tenner B, Lin W, Zhang JZ, Molina RS, Drobizhev M, Hughes TE, Tian L, Huganir RL, Mehta S, Zhang J. An ultrasensitive biosensor for high-resolution kinase activity imaging in awake mice. Nature Chemical Biology. PMID 32989297 DOI: 10.1038/s41589-020-00660-y  0.64
2020 Zhang JZ, Lu TW, Stolerman LM, Tenner B, Yang JR, Zhang JF, Falcke M, Rangamani P, Taylor SS, Mehta S, Zhang J. Phase Separation of a PKA Regulatory Subunit Controls cAMP Compartmentation and Oncogenic Signaling. Cell. PMID 32846158 DOI: 10.1016/j.cell.2020.07.043  0.64
2020 Zhou X, Mehta S, Zhang J. Genetically Encodable Fluorescent and Bioluminescent Biosensors Light Up Signaling Networks. Trends in Biochemical Sciences. PMID 32660810 DOI: 10.1016/j.tibs.2020.06.001  0.64
2020 Mo GCH, Posner C, Rodriguez EA, Sun T, Zhang J. A rationally enhanced red fluorescent protein expands the utility of FRET biosensors. Nature Communications. 11: 1848. PMID 32296061 DOI: 10.1038/s41467-020-15687-x  0.72
2020 Wang XJ, Xu XQ, Sun K, Liu KQ, Li SQ, Jiang X, Zhao QH, Wang L, Peng FH, Ye J, Wu Y, Jiang R, Zhang J, Huang W, Wei WB, et al. Association of Rare PTGIS Variants With Susceptibility and Pulmonary Vascular Response in Patients With Idiopathic Pulmonary Arterial Hypertension. Jama Cardiology. PMID 32236489 DOI: 10.1001/jamacardio.2020.0479  0.56
2020 Lee HN, Mehta S, Zhang J. Recent advances in the use of genetically encodable optical tools to elicit and monitor signaling events. Current Opinion in Cell Biology. 63: 114-124. PMID 32058267 DOI: 10.1016/j.ceb.2020.01.007  0.64
2020 Schmitt DL, Mehta S, Zhang J. Illuminating the kinome: Visualizing real-time kinase activity in biological systems using genetically encoded fluorescent protein-based biosensors. Current Opinion in Chemical Biology. 54: 63-69. PMID 31911398 DOI: 10.1016/j.cbpa.2019.11.005  0.64
2019 Hertel F, Li S, Chen M, Pott L, Mehta S, Zhang J. Fluorescent biosensors for multiplexed imaging of phosphoinositide dynamics. Acs Chemical Biology. PMID 31855412 DOI: 10.1021/acschembio.9b00691  0.64
2019 Lin W, Mehta S, Zhang J. Genetically encoded fluorescent biosensors illuminate kinase signaling in cancer. The Journal of Biological Chemistry. PMID 31434714 DOI: 10.1074/jbc.REV119.006177  0.64
2019 Clister T, Greenwald EC, Baillie GS, Zhang J. AKAP95 Organizes a Nuclear Microdomain to Control Local cAMP for Regulating Nuclear PKA. Cell Chemical Biology. PMID 30982750 DOI: 10.1016/j.chembiol.2019.03.003  0.64
2018 Greenwald EC, Mehta S, Zhang J. Genetically Encoded Fluorescent Biosensors Illuminate the Spatiotemporal Regulation of Signaling Networks. Chemical Reviews. PMID 30550275 DOI: 10.1021/acs.chemrev.8b00333  0.64
2018 Grimsey NJ, Narala R, Rada CC, Mehta S, Stephens BS, Kufareva I, Lapek J, Gonzalez DJ, Handel TM, Zhang J, Trejo J. A Tyrosine Switch on NEDD4-2 E3 Ligase Transmits GPCR Inflammatory Signaling. Cell Reports. 24: 3312-3323.e5. PMID 30232011 DOI: 10.1016/j.celrep.2018.08.061  0.64
2017 Mehta S, Zhang J. Illuminating the cell's biochemical activity architecture. Biochemistry. PMID 28718621 DOI: 10.1021/acs.biochem.7b00561  0.64
2017 Ni Q, Mehta S, Zhang J. Live-cell imaging of cell signaling using genetically encoded fluorescent reporters. The Febs Journal. PMID 28613457 DOI: 10.1111/febs.14134  0.64
2016 Rodriguez EA, Campbell RE, Lin JY, Lin MZ, Miyawaki A, Palmer AE, Shu X, Zhang J, Tsien RY. The Growing and Glowing Toolbox of Fluorescent and Photoactive Proteins. Trends in Biochemical Sciences. PMID 27814948 DOI: 10.1016/j.tibs.2016.09.010  1
2016 Palmer AE, Zhang J. Roger Y. Tsien 1952-2016. Nature Chemical Biology. PMID 27669418 DOI: 10.1038/nchembio.2213  1
2016 Ross B, Mehta S, Zhang J. Molecular tools for acute spatiotemporal manipulation of signal transduction. Current Opinion in Chemical Biology. 34: 135-142. PMID 27639090 DOI: 10.1016/j.cbpa.2016.08.012  0.64
2016 Tenner B, Mehta S, Zhang J. Optical sensors to gain mechanistic insights into signaling assemblies. Current Opinion in Structural Biology. 41: 203-210. PMID 27611602 DOI: 10.1016/j.sbi.2016.07.021  0.64
2016 Hung WC, Yang JR, Yankaskas CL, Wong BS, Wu PH, Pardo-Pastor C, Serra SA, Chiang MJ, Gu Z, Wirtz D, Valverde MA, Yang JT, Zhang J, Konstantopoulos K. Confinement-Sensing and Signal Optimization via Piezo1/PKA and Myosin II Pathways. Cell Reports. PMID 27160899 DOI: 10.1016/j.celrep.2016.04.035  1
2015 Depry C, Mehta S, Li R, Zhang J. Visualization of Compartmentalized Kinase Activity Dynamics Using Adaptable BimKARs. Chemistry & Biology. PMID 26548610 DOI: 10.1016/j.chembiol.2015.10.004  1
2015 Yaniv Y, Ganesan A, Yang D, Ziman BD, Lyashkov AE, Levchenko A, Zhang J, Lakatta EG. Real-time relationship between PKA biochemical signal network dynamics and increased action potential firing rate in heart pacemaker cells: Yaniv. Kinetics of PKA activation in heart pacemaker cells. Journal of Molecular and Cellular Cardiology. PMID 26241846 DOI: 10.1016/j.yjmcc.2015.07.024  1
2015 Karlsson I, Zhou X, Thomas R, Smith AT, Bonner MY, Bakshi P, Banga AK, Bowen JP, Qabaja G, Ford SL, Ballard MD, Petersen KS, Li X, Chen G, Ogretmen B, ... Zhang J, et al. Solenopsin A and analogs exhibit ceramide-like biological activity. Vascular Cell. 7: 5. PMID 26015865 DOI: 10.1186/s13221-015-0030-2  1
2015 Sample V, Ramamurthy S, Gorshkov K, Ronnett GV, Zhang J. Polarized activities of AMPK and BRSK in primary hippocampal neurons. Molecular Biology of the Cell. 26: 1935-46. PMID 25788287 DOI: 10.1091/mbc.E14-02-0764  1
2015 Zhou X, Clister TL, Lowry PR, Seldin MM, Wong GW, Zhang J. Dynamic Visualization of mTORC1 Activity in Living Cells. Cell Reports. PMID 25772363 DOI: 10.1016/j.celrep.2015.02.031  1
2015 Mehta S, Zhang J. Dynamic visualization of calcium-dependent signaling in cellular microdomains. Cell Calcium. PMID 25703691 DOI: 10.1016/j.ceca.2015.01.009  1
2015 Weng HJ, Patel KN, Jeske NA, Bierbower SM, Zou W, Tiwari V, Zheng Q, Tang Z, Mo GC, Wang Y, Geng Y, Zhang J, Guan Y, Akopian AN, Dong X. Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain. Neuron. 85: 833-46. PMID 25640077 DOI: 10.1016/j.neuron.2014.12.065  1
2015 Ding Y, Li J, Enterina JR, Shen Y, Zhang I, Tewson PH, Mo GC, Zhang J, Quinn AM, Hughes TE, Maysinger D, Alford SC, Zhang Y, Campbell RE. Ratiometric biosensors based on dimerization-dependent fluorescent protein exchange. Nature Methods. 12: 195-8. PMID 25622108 DOI: 10.1038/nmeth.3261  1
2015 Clister T, Mehta S, Zhang J. Single-cell analysis of G-protein signal transduction. The Journal of Biological Chemistry. 290: 6681-8. PMID 25605723 DOI: 10.1074/jbc.R114.616391  1
2015 Mehta S, Zhang J. Light moves mountains in the cell Chemistry and Biology. 22: 559-560. DOI: 10.1016/j.chembiol.2015.05.002  1
2014 Newman RH, Zhang J, Zhu H. Toward a systems-level view of dynamic phosphorylation networks. Frontiers in Genetics. 5: 263. PMID 25177341 DOI: 10.3389/fgene.2014.00263  1
2014 Kim TJ, Sun J, Lu S, Zhang J, Wang Y. The regulation of β-adrenergic receptor-mediated PKA activation by substrate stiffness via microtubule dynamics in human MSCs. Biomaterials. 35: 8348-56. PMID 24973298 DOI: 10.1016/j.biomaterials.2014.06.018  1
2014 Sample V, Mehta S, Zhang J. Genetically encoded molecular probes to visualize and perturb signaling dynamics in living biological systems. Journal of Cell Science. 127: 1151-60. PMID 24634506 DOI: 10.1242/jcs.099994  1
2014 Oldach L, Zhang J. Genetically encoded fluorescent biosensors for live-cell visualization of protein phosphorylation Chemistry and Biology. 21: 186-197. PMID 24485761 DOI: 10.1016/j.chembiol.2013.12.012  1
2014 Wang Y, Ho TG, Bertinetti D, Neddermann M, Franz E, Mo GC, Schendowich LP, Sukhu A, Spelts RC, Zhang J, Herberg FW, Kennedy EJ. Isoform-selective disruption of AKAP-localized PKA using hydrocarbon stapled peptides. Acs Chemical Biology. 9: 635-42. PMID 24422448 DOI: 10.1021/cb400900r  1
2014 Robinson KH, Yang JR, Zhang J. FRET and BRET-based biosensors in live cell compound screens. Methods in Molecular Biology (Clifton, N.J.). 1071: 217-25. PMID 24052392 DOI: 10.1007/978-1-62703-622-1_17  1
2014 Newman RH, Zhang J. The design and application of genetically encodable biosensors based on fluorescent proteins. Methods in Molecular Biology (Clifton, N.J.). 1071: 1-16. PMID 24052376 DOI: 10.1007/978-1-62703-622-1_1  1
2014 Hu J, Rho HS, Newman RH, Hwang W, Neiswinger J, Zhu H, Zhang J, Qian J. Global analysis of phosphorylation networks in humans. Biochimica Et Biophysica Acta. 1844: 224-31. PMID 23524292 DOI: 10.1016/j.bbapap.2013.03.009  1
2014 Aye-Han NN, Zhang J. A multiparameter live cell imaging approach to monitor cyclic AMP and protein kinase a dynamics in parallel Methods in Molecular Biology. 1071: 207-215. DOI: 10.1007/978-1-62703-622-1_16  1
2014 Mehta S, Zhang J. Using a genetically encoded FRET-based reporter to visualize calcineurin phosphatase activity in living cells Methods in Molecular Biology. 1071: 139-149. DOI: 10.1007/978-1-62703-622-1_11  1
2013 Mehta S, Zhang J. Using a kinase-inducible bimolecular switch to control enzyme activity in living cells. Current Protocols in Chemical Biology. 5: 227-37. PMID 24391085 DOI: 10.1002/9780470559277.ch130090  0.64
2013 Burdyga A, Conant A, Haynes L, Zhang J, Jalink K, Sutton R, Neoptolemos J, Costello E, Tepikin A. cAMP inhibits migration, ruffling and paxillin accumulation in focal adhesions of pancreatic ductal adenocarcinoma cells: effects of PKA and EPAC. Biochimica Et Biophysica Acta. 1833: 2664-72. PMID 23797058 DOI: 10.1016/j.bbamcr.2013.06.011  1
2013 Newman RH, Hu J, Rho HS, Xie Z, Woodard C, Neiswinger J, Cooper C, Shirley M, Clark HM, Hu S, Hwang W, Jeong JS, Wu G, Lin J, Gao X, ... ... Zhang J, et al. Construction of human activity-based phosphorylation networks. Molecular Systems Biology. 9: 655. PMID 23549483 DOI: 10.1038/msb.2013.12  1
2013 Depry C, Mehta S, Zhang J. Multiplexed visualization of dynamic signaling networks using genetically encoded fluorescent protein-based biosensors Pflugers Archiv European Journal of Physiology. 465: 373-381. PMID 23138230 DOI: 10.1007/s00424-012-1175-y  1
2013 Sample V, Ni Q, Mehta S, Inoue T, Zhang J. Controlling enzymatic action in living cells with a kinase-inducible bimolecular switch Acs Chemical Biology. 8: 116-121. PMID 23072367 DOI: 10.1021/cb300393w  1
2012 Nunes AR, Sample V, Xiang YK, Monteiro EC, Gauda E, Zhang J. Effect of oxygen on phosphodiesterases (PDE) 3 and 4 isoforms and PKA activity in the superior cervical ganglia Advances in Experimental Medicine and Biology. 758: 287-294. PMID 23080174 DOI: 10.1007/978-94-007-4584-1_39  1
2012 Dancy BM, Crump NT, Peterson DJ, Mukherjee C, Bowers EM, Ahn YH, Yoshida M, Zhang J, Mahadevan LC, Meyers DJ, Boeke JD, Cole PA. Live-cell studies of p300/CBP histone acetyltransferase activity and inhibition. Chembiochem : a European Journal of Chemical Biology. 13: 2113-21. PMID 22961914 DOI: 10.1002/cbic.201200381  1
2012 Ganesan A, Zhang J. How cells process information: quantification of spatiotemporal signaling dynamics. Protein Science : a Publication of the Protein Society. 21: 918-28. PMID 22573643 DOI: 10.1002/pro.2089  1
2012 Sample V, DiPilato LM, Yang JH, Ni Q, Saucerman JJ, Zhang J. Regulation of nuclear PKA revealed by spatiotemporal manipulation of cyclic AMP. Nature Chemical Biology. 8: 375-82. PMID 22366721 DOI: 10.1038/nchembio.799  1
2012 Zhou X, Herbst-Robinson KJ, Zhang J. Visualizing dynamic activities of signaling enzymes using genetically encodable FRET-based biosensors: From designs to applications Methods in Enzymology. 504: 317-340. PMID 22264542 DOI: 10.1016/B978-0-12-391857-4.00016-1  1
2012 del Puerto A, Díaz-Hernández JI, Tapia M, Gomez-Villafuertes R, Benitez MJ, Zhang J, Miras-Portugal MT, Wandosell F, Díaz-Hernández M, Garrido JJ. Adenylate cyclase 5 coordinates the action of ADP, P2Y1, P2Y13 and ATP-gated P2X7 receptors on axonal elongation. Journal of Cell Science. 125: 176-88. PMID 22250198 DOI: 10.1242/jcs.091736  1
2011 Gao X, Lowry PR, Zhou X, Depry C, Wei Z, Wong GW, Zhang J. PI3K/Akt signaling requires spatial compartmentalization in plasma membrane microdomains. Proceedings of the National Academy of Sciences of the United States of America. 108: 14509-14. PMID 21873248 DOI: 10.1073/pnas.1019386108  1
2011 Depry C, Zhang J. Using FRET-based reporters to visualize subcellular dynamics of protein kinase A activity Methods in Molecular Biology. 756: 285-294. PMID 21870233 DOI: 10.1007/978-1-61779-160-4_16  1
2011 Newman RH, Fosbrink MD, Zhang J. Genetically encodable fluorescent biosensors for tracking signaling dynamics in living cells. Chemical Reviews. 111: 3614-66. PMID 21456512 DOI: 10.1021/cr100002u  1
2011 Herbst KJ, Allen MD, Zhang J. Luminescent kinase activity biosensors based on a versatile bimolecular switch Journal of the American Chemical Society. 133: 5676-5679. PMID 21438554 DOI: 10.1021/ja1117396  1
2011 Wan M, Li J, Herbst K, Zhang J, Yu B, Wu X, Qiu T, Lei W, Lindvall C, Williams BO, Ma H, Zhang F, Cao X. LRP6 mediates cAMP generation by G protein-coupled receptors through regulating the membrane targeting of Gα(s). Science Signaling. 4: ra15. PMID 21406690 DOI: 10.1126/scisignal.2001464  1
2011 Herbst KJ, Coltharp C, Amzel LM, Zhang J. Direct activation of Epac by sulfonylurea is isoform selective Chemistry and Biology. 18: 243-251. PMID 21338921 DOI: 10.1016/j.chembiol.2010.12.007  1
2011 Ni Q, Ganesan A, Aye-Han NN, Gao X, Allen MD, Levchenko A, Zhang J. Signaling diversity of PKA achieved via a Ca2+-cAMP-PKA oscillatory circuit. Nature Chemical Biology. 7: 34-40. PMID 21102470 DOI: 10.1038/nchembio.478  1
2010 Gildea JJ, Shah I, Weiss R, Casscells ND, McGrath HE, Zhang J, Jones JE, Felder RA. HK-2 human renal proximal tubule cells as a model for G protein-coupled receptor kinase type 4-mediated dopamine 1 receptor uncoupling. Hypertension. 56: 505-11. PMID 20660820 DOI: 10.1161/HYPERTENSIONAHA.110.152256  1
2010 Depry C, Zhang J. Visualization of kinase activity with FRET-based activity biosensors Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 18.15. PMID 20583095 DOI: 10.1002/0471142727.mb1815s91  1
2010 Fosbrink M, Aye-Han NN, Cheong R, Levchenko A, Zhang J. Visualization of JNK activity dynamics with a genetically encoded fluorescent biosensor. Proceedings of the National Academy of Sciences of the United States of America. 107: 5459-64. PMID 20212108 DOI: 10.1073/pnas.0909671107  1
2010 Gao X, Zhang J. FRET-based activity biosensors to probe compartmentalized signaling Chembiochem. 11: 147-151. PMID 20014085 DOI: 10.1002/cbic.200900594  1
2010 DiPilato LM, Zhang J. Fluorescent protein-based biosensors: resolving spatiotemporal dynamics of signaling. Current Opinion in Chemical Biology. 14: 37-42. PMID 19910237 DOI: 10.1016/j.cbpa.2009.10.012  1
2010 Ni Q, Zhang J. Dynamic Visualization of cellular signaling Advances in Biochemical Engineering/Biotechnology. 119: 79-97. PMID 19499207 DOI: 10.1007/10_2008_48  1
2009 Herbst KJ, Ni Q, Zhang J. Dynamic visualization of signal transduction in living cells: From second messengers to kinases Iubmb Life. 61: 902-908. PMID 19603514 DOI: 10.1002/iub.232  1
2009 DiPilato LM, Zhang J. The role of membrane microdomains in shaping beta2-adrenergic receptor-mediated cAMP dynamics. Molecular Biosystems. 5: 832-7. PMID 19603118 DOI: 10.1039/b823243a  1
2009 Herbst KJ, Allen MD, Zhang J. The cAMP-dependent protein kinase inhibitor H-89 attenuates the bioluminescence signal produced by Renilla Luciferase. Plos One. 4: e5642. PMID 19461967 DOI: 10.1371/journal.pone.0005642  1
2009 Zhang J. The colorful journey of green fluorescent protein Acs Chemical Biology. 4: 85-88. PMID 19228068 DOI: 10.1021/cb900027r  1
2009 Rahdar M, Inoue T, Meyer T, Zhang J, Vazquez F, Devreotes PN. A phosphorylation-dependent intramolecular interaction regulates the membrane association and activity of the tumor suppressor PTEN. Proceedings of the National Academy of Sciences of the United States of America. 106: 480-5. PMID 19114656 DOI: 10.1073/pnas.0811212106  1
2008 Vincent P, Gervasi N, Zhang J. Real-time monitoring of cyclic nucleotide signaling in neurons using genetically encoded FRET probes. Brain Cell Biology. 36: 3-17. PMID 18941898 DOI: 10.1007/s11068-008-9035-6  1
2008 Allen MD, DiPilato LM, Ananthanarayanan B, Newman RH, Ni Q, Zhang J. Dynamic visualization of signaling activities in living cells. Science Signaling. 1: pt6. PMID 18799423 DOI: 10.1126/scisignal.137pt6  1
2008 Lim CJ, Kain KH, Tkachenko E, Goldfinger LE, Gutierrez E, Allen MD, Groisman A, Zhang J, Ginsberg MH. Integrin-mediated protein kinase A activation at the leading edge of migrating cells. Molecular Biology of the Cell. 19: 4930-41. PMID 18784251 DOI: 10.1091/mbc.E08-06-0564  1
2008 Szewczuk LM, Tarrant MK, Sample V, Drury WJ, Zhang J, Cole PA. Analysis of serotonin N-acetyltransferase regulation in vitro and in live cells using protein semisynthesis. Biochemistry. 47: 10407-19. PMID 18771288 DOI: 10.1021/bi801189d  1
2008 Gao X, Zhang J. Spatiotemporal analysis of differential Akt regulation in plasma membrane microdomains Molecular Biology of the Cell. 19: 4366-4373. PMID 18701703 DOI: 10.1091/mbc.E08-05-0449  1
2008 Newman RH, Zhang J. Visualization of phosphatase activity in living cells with a FRET-based calcineurin activity sensor Molecular Biosystems. 4: 496-501. PMID 18493642 DOI: 10.1039/b720034j  1
2008 Allen MD, Zhang J. A tunable FRET circuit for engineering fluorescent biosensors. Angewandte Chemie (International Ed. in English). 47: 500-2. PMID 18058965 DOI: 10.1002/anie.200703493  1
2008 Violin JD, DiPilato LM, Yildirim N, Elston TC, Zhang J, Lefkowitz RJ. beta2-adrenergic receptor signaling and desensitization elucidated by quantitative modeling of real time cAMP dynamics. The Journal of Biological Chemistry. 283: 2949-61. PMID 18045878 DOI: 10.1074/jbc.M707009200  1
2007 Zhang J, Allen MD. FRET-based biosensors for protein kinases: illuminating the kinome. Molecular Biosystems. 3: 759-65. PMID 17940658 DOI: 10.1039/b706628g  1
2007 Ananthanarayanan B, Fosbrink M, Rahdar M, Zhang J. Live-cell molecular analysis of Akt activation reveals roles for activation loop phosphorylation. The Journal of Biological Chemistry. 282: 36634-41. PMID 17928291 DOI: 10.1074/jbc.M706227200  1
2007 Sachs BD, Baillie GS, McCall JR, Passino MA, Schachtrup C, Wallace DA, Dunlop AJ, MacKenzie KF, Klussmann E, Lynch MJ, Sikorski SL, Nuriel T, Tsigelny I, Zhang J, Houslay MD, et al. p75 neurotrophin receptor regulates tissue fibrosis through inhibition of plasminogen activation via a PDE4/cAMP/PKA pathway. The Journal of Cell Biology. 177: 1119-32. PMID 17576803 DOI: 10.1083/jcb.200701040  1
2007 Maresh J, Zhang J, Tzeng YL, Goodman NA, Lynn DG. Rational design of inhibitors of VirA-VirG two-component signal transduction. Bioorganic & Medicinal Chemistry Letters. 17: 3281-6. PMID 17470391 DOI: 10.1016/j.bmcl.2007.04.018  1
2007 Gervasi N, Hepp R, Tricoire L, Zhang J, Lambolez B, Paupardin-Tritsch D, Vincent P. Dynamics of protein kinase A signaling at the membrane, in the cytosol, and in the nucleus of neurons in mouse brain slices. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 2744-50. PMID 17360896 DOI: 10.1523/JNEUROSCI.5352-06.2007  1
2006 Allen MD, DiPilato LM, Rahdar M, Ren YR, Chong C, Liu JO, Zhang J. Reading dynamic kinase activity in living cells for high-throughput screening. Acs Chemical Biology. 1: 371-6. PMID 17163774 DOI: 10.1021/cb600202f  1
2006 Maresh J, Zhang J, Lynn DG. The innate immunity of maize and the dynamic chemical strategies regulating two-component signal transduction in Agrobacterium tumefaciens. Acs Chemical Biology. 1: 165-75. PMID 17163664 DOI: 10.1021/cb600051w  1
2006 Dunn TA, Wang CT, Colicos MA, Zaccolo M, DiPilato LM, Zhang J, Tsien RY, Feller MB. Imaging of cAMP levels and protein kinase A activity reveals that retinal waves drive oscillations in second-messenger cascades. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 12807-15. PMID 17151284 DOI: 10.1523/JNEUROSCI.3238-06.2006  1
2006 DiPilato LM, Zhang J. FRETting mice shed light on cardiac adrenergic signaling. Circulation Research. 99: 1021-3. PMID 17095728 DOI: 10.1161/01.RES.0000250962.61995.cf  1
2006 Ni Q, Titov DV, Zhang J. Analyzing protein kinase dynamics in living cells with FRET reporters. Methods (San Diego, Calif.). 40: 279-86. PMID 16908183 DOI: 10.1016/j.ymeth.2006.06.013  1
2006 Saucerman JJ, Zhang J, Martin JC, Peng LX, Stenbit AE, Tsien RY, McCulloch AD. Systems analysis of PKA-mediated phosphorylation gradients in live cardiac myocytes. Proceedings of the National Academy of Sciences of the United States of America. 103: 12923-8. PMID 16905651 DOI: 10.1073/pnas.0600137103  1
2006 Allen MD, Zhang J. Subcellular dynamics of protein kinase A activity visualized by FRET-based reporters. Biochemical and Biophysical Research Communications. 348: 716-21. PMID 16895723 DOI: 10.1016/j.bbrc.2006.07.136  1
2006 Qiao Y, Molina H, Pandey A, Zhang J, Cole PA. Chemical rescue of a mutant enzyme in living cells. Science (New York, N.Y.). 311: 1293-7. PMID 16513984 DOI: 10.1126/science.1122224  1
2005 Ananthanarayanan B, Ni Q, Zhang J. Signal propagation from membrane messengers to nuclear effectors revealed by reporters of phosphoinositide dynamics and Akt activity. Proceedings of the National Academy of Sciences of the United States of America. 102: 15081-6. PMID 16214892 DOI: 10.1073/pnas.0502889102  1
2005 Zhang J, Hupfeld CJ, Taylor SS, Olefsky JM, Tsien RY. Insulin disrupts beta-adrenergic signalling to protein kinase A in adipocytes. Nature. 437: 569-73. PMID 16177793 DOI: 10.1038/nature04140  1
2005 Kunkel MT, Ni Q, Tsien RY, Zhang J, Newton AC. Spatio-temporal dynamics of protein kinase B/Akt signaling revealed by a genetically encoded fluorescent reporter. The Journal of Biological Chemistry. 280: 5581-7. PMID 15583002 DOI: 10.1074/jbc.M411534200  1
2004 DiPilato LM, Cheng X, Zhang J. Fluorescent indicators of cAMP and Epac activation reveal differential dynamics of cAMP signaling within discrete subcellular compartments. Proceedings of the National Academy of Sciences of the United States of America. 101: 16513-8. PMID 15545605 DOI: 10.1073/pnas.0405973101  1
2003 Violin JD, Zhang J, Tsien RY, Newton AC. A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C. The Journal of Cell Biology. 161: 899-909. PMID 12782683 DOI: 10.1083/jcb.200302125  1
2002 Zhang J, Campbell RE, Ting AY, Tsien RY. Creating new fluorescent probes for cell biology. Nature Reviews. Molecular Cell Biology. 3: 906-18. PMID 12461557 DOI: 10.1038/nrm976  1
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