| Year |
Citation |
Score |
| 2024 |
Su Q, Zhang J, Lin W, Zhang JF, Newton AC, Mehta S, Yang J, Zhang J. Sensitive Fluorescent Biosensor Reveals Differential Subcellular Regulation of PKC. Biorxiv : the Preprint Server For Biology. PMID 38586003 DOI: 10.1101/2024.03.29.587373 |
0.435 |
|
| 2024 |
Lin W, Phatarphekar A, Zhong Y, Liu L, Kwon HB, Gerwick WH, Wang Y, Mehta S, Zhang J. Light-gated Integrator for Highlighting Kinase Activity in Living Cells. Biorxiv : the Preprint Server For Biology. PMID 38562887 DOI: 10.1101/2024.03.18.585554 |
0.471 |
|
| 2024 |
Hardy JC, Pool EH, Bruystens JGH, Zhou X, Li Q, Zhou DR, Palay M, Tan G, Chen L, Choi JLC, Lee HN, Strack S, Wang D, Taylor SS, Mehta S, ... Zhang J, et al. Molecular determinants and signaling effects of PKA RIα phase separation. Molecular Cell. PMID 38537638 DOI: 10.1016/j.molcel.2024.03.002 |
0.391 |
|
| 2024 |
Frei MS, Sanchez SA, Liu L, Schneider F, Wang Z, Hakozaki H, Li Y, Lyons AC, Rohm TV, Olefsky JM, Shi L, Schöneberg J, Fraser SE, Mehta S, Wang Y, ... Zhang J, et al. Far-red chemigenetic biosensors for multi-dimensional and super-resolved kinase activity imaging. Biorxiv : the Preprint Server For Biology. PMID 38370804 DOI: 10.1101/2024.02.10.579766 |
0.347 |
|
| 2023 |
Hardy JC, Pool EH, Bruystens JGH, Zhou X, Li Q, Zhou DR, Palay M, Tan G, Chen L, Choi JLC, Lee HN, Strack S, Wang D, Taylor SS, Mehta S, ... Zhang J, et al. Molecular Determinants and Signaling Effects of PKA RIα Phase Separation. Biorxiv : the Preprint Server For Biology. PMID 38168176 DOI: 10.1101/2023.12.10.570836 |
0.385 |
|
| 2023 |
Lyons AC, Mehta S, Zhang J. Fluorescent biosensors illuminate the spatial regulation of cell signaling across scales. The Biochemical Journal. 480: 1693-1717. PMID 37903110 DOI: 10.1042/BCJ20220223 |
0.348 |
|
| 2023 |
Posner C, Mehta S, Zhang J. Fluorescent biosensor imaging meets deterministic mathematical modelling: quantitative investigation of signalling compartmentalization. The Journal of Physiology. 601: 4227-4241. PMID 37747358 DOI: 10.1113/JP282696 |
0.398 |
|
| 2023 |
Willette BKA, Zhang JF, Zhang J, Tsvetanova NG. Endosome positioning coordinates spatially selective GPCR signaling. Nature Chemical Biology. PMID 37500769 DOI: 10.1038/s41589-023-01390-7 |
0.372 |
|
| 2023 |
Elias RD, Zhu Y, Su Q, Ghirlando R, Zhang J, Deshmukh L. Reversible phase separation of ESCRT protein ALIX through tyrosine phosphorylation. Science Advances. 9: eadg3913. PMID 37450591 DOI: 10.1126/sciadv.adg3913 |
0.302 |
|
| 2023 |
Greenwald E, Posner C, Bharath A, Lyons A, Salmerón C, Sriram K, Wiley SZ, Insel PA, Zhang J. GPCR Signaling Measurement and Drug Profiling with an Automated Live-Cell Microscopy System. Acs Sensors. PMID 36602887 DOI: 10.1021/acssensors.2c01341 |
0.782 |
|
| 2022 |
Peng Q, Huang Z, Sun K, Liu Y, Yoon CW, Harrison RES, Schmitt DL, Zhu L, Wu Y, Tasan I, Zhao H, Zhang J, Zhong S, Chien S, Wang Y. Engineering inducible biomolecular assemblies for genome imaging and manipulation in living cells. Nature Communications. 13: 7933. PMID 36566209 DOI: 10.1038/s41467-022-35504-x |
0.645 |
|
| 2022 |
Schmitt DL, Mehta S, Zhang J. Study of spatiotemporal regulation of kinase signaling using genetically encodable molecular tools. Current Opinion in Chemical Biology. 71: 102224. PMID 36347198 DOI: 10.1016/j.cbpa.2022.102224 |
0.74 |
|
| 2022 |
Kwon Y, Mehta S, Clark M, Walters G, Zhong Y, Lee HN, Sunahara RK, Zhang J. Non-canonical β-adrenergic activation of ERK at endosomes. Nature. PMID 36289326 DOI: 10.1038/s41586-022-05343-3 |
0.419 |
|
| 2022 |
Hashizume R, Fujii H, Mehta S, Ota K, Qian Y, Zhu W, Drobizhev M, Nasu Y, Zhang J, Bito H, Campbell RE. A genetically encoded far-red fluorescent calcium ion biosensor derived from a biliverdin-binding protein. Protein Science : a Publication of the Protein Society. 31: e4440. PMID 36173169 DOI: 10.1002/pro.4440 |
0.49 |
|
| 2022 |
Schmitt DL, Curtis SD, Lyons AC, Zhang JF, Chen M, He CY, Mehta S, Shaw RJ, Zhang J. Spatial regulation of AMPK signaling revealed by a sensitive kinase activity reporter. Nature Communications. 13: 3856. PMID 35790710 DOI: 10.1038/s41467-022-31190-x |
0.747 |
|
| 2022 |
Zhou X, Mehta S, Zhang J. AktAR and Akt-STOPS: Genetically Encodable Molecular Tools to Visualize and Perturb Akt Kinase Activity at Different Subcellular Locations in Living Cells. Current Protocols. 2: e416. PMID 35532280 DOI: 10.1002/cpz1.416 |
0.457 |
|
| 2022 |
Hardy JC, Mehta S, Zhang J. Measuring Spatiotemporal cAMP Dynamics Within an Endogenous Signaling Compartment Using FluoSTEP-ICUE. Methods in Molecular Biology (Clifton, N.J.). 2483: 351-366. PMID 35286687 DOI: 10.1007/978-1-0716-2245-2_22 |
0.398 |
|
| 2022 |
Zhang JF, Mehta S, Zhang J. Protocol for reading and imaging live-cell PKA activity using ExRai-AKAR2. Star Protocols. 3: 101071. PMID 35036953 DOI: 10.1016/j.xpro.2021.101071 |
0.353 |
|
| 2021 |
Chen M, Sun T, Zhong Y, Zhou X, Zhang J. A Highly Sensitive Fluorescent Akt Biosensor Reveals Lysosome-Selective Regulation of Lipid Second Messengers and Kinase Activity. Acs Central Science. 7: 2009-2020. PMID 34963894 DOI: 10.1021/acscentsci.1c00919 |
0.397 |
|
| 2021 |
Liu L, Limsakul P, Meng X, Huang Y, Harrison RES, Huang TS, Shi Y, Yu Y, Charupanit K, Zhong S, Lu S, Zhang J, Chien S, Sun J, Wang Y. Integration of FRET and sequencing to engineer kinase biosensors from mammalian cell libraries. Nature Communications. 12: 5031. PMID 34413312 DOI: 10.1038/s41467-021-25323-x |
0.31 |
|
| 2021 |
Keyes J, Mehta S, Zhang J. Strategies for Multiplexed Biosensor Imaging to Study Intracellular Signaling Networks. Methods in Molecular Biology (Clifton, N.J.). 2350: 1-20. PMID 34331275 DOI: 10.1007/978-1-0716-1593-5_1 |
0.332 |
|
| 2021 |
Zhao S, Geng Y, Cao L, Yang Q, Pan T, Zhou D, Liu J, Shi Z, Zhang J. Deciphering the performance of polo-like kinase 1 in triple-negative breast cancer progression according to the centromere protein U-phosphorylation pathway. American Journal of Cancer Research. 11: 2142-2158. PMID 34094674 |
0.304 |
|
| 2021 |
Tenner B, Zhang JZ, Kwon Y, Pessino V, Feng S, Huang B, Mehta S, Zhang J. FluoSTEPs: Fluorescent biosensors for monitoring compartmentalized signaling within endogenous microdomains. Science Advances. 7. PMID 34020947 DOI: 10.1126/sciadv.abe4091 |
0.423 |
|
| 2021 |
Mehta S, Zhang J. Biochemical Activity Architectures Visualized-Using Genetically Encoded Fluorescent Biosensors to Map the Spatial Boundaries of Signaling Compartments. Accounts of Chemical Research. PMID 33949851 DOI: 10.1021/acs.accounts.1c00056 |
0.431 |
|
| 2021 |
Roebroek T, Vandenberg W, Sipieter F, Hugelier S, Stove C, Zhang J, Dedecker P. Simultaneous readout of multiple FRET pairs using photochromism. Nature Communications. 12: 2005. PMID 33790271 DOI: 10.1038/s41467-021-22043-0 |
0.337 |
|
| 2021 |
Zhang JF, Mehta S, Zhang J. Signaling Microdomains in the Spotlight: Visualizing Compartmentalized Signaling Using Genetically Encoded Fluorescent Biosensors. Annual Review of Pharmacology and Toxicology. 61: 587-608. PMID 33411579 DOI: 10.1146/annurev-pharmtox-010617-053137 |
0.356 |
|
| 2020 |
Tenner B, Getz M, Ross B, Ohadi D, Bohrer CH, Greenwald E, Mehta S, Xiao J, Rangamani P, Zhang J. Spatially compartmentalized phase regulation of a Ca-cAMP-PKA oscillatory circuit. Elife. 9. PMID 33201801 DOI: 10.7554/eLife.55013 |
0.735 |
|
| 2020 |
Zhang JF, Liu B, Hong I, Mo A, Roth RH, Tenner B, Lin W, Zhang JZ, Molina RS, Drobizhev M, Hughes TE, Tian L, Huganir RL, Mehta S, Zhang J. An ultrasensitive biosensor for high-resolution kinase activity imaging in awake mice. Nature Chemical Biology. PMID 32989297 DOI: 10.1038/s41589-020-00660-y |
0.47 |
|
| 2020 |
Zhang JZ, Nguyen AH, Miyamoto S, Heller Brown J, McCulloch AD, Zhang J. Histamine-induced biphasic activation of RhoA allows for persistent RhoA signaling. Plos Biology. 18: e3000866. PMID 32881857 DOI: 10.1371/Journal.Pbio.3000866 |
0.488 |
|
| 2020 |
Zhang JZ, Lu TW, Stolerman LM, Tenner B, Yang JR, Zhang JF, Falcke M, Rangamani P, Taylor SS, Mehta S, Zhang J. Phase Separation of a PKA Regulatory Subunit Controls cAMP Compartmentation and Oncogenic Signaling. Cell. PMID 32846158 DOI: 10.1016/J.Cell.2020.07.043 |
0.508 |
|
| 2020 |
Zhou X, Mehta S, Zhang J. Genetically Encodable Fluorescent and Bioluminescent Biosensors Light Up Signaling Networks. Trends in Biochemical Sciences. PMID 32660810 DOI: 10.1016/J.Tibs.2020.06.001 |
0.416 |
|
| 2020 |
Keyes J, Ganesan A, Molinar-Inglis O, Hamidzadeh A, Zhang J, Ling M, Trejo J, Levchenko A, Zhang J. Signaling diversity enabled by Rap1-regulated plasma membrane ERK with distinct temporal dynamics. Elife. 9. PMID 32452765 DOI: 10.7554/Elife.57410 |
0.501 |
|
| 2020 |
Mo GCH, Posner C, Rodriguez EA, Sun T, Zhang J. A rationally enhanced red fluorescent protein expands the utility of FRET biosensors. Nature Communications. 11: 1848. PMID 32296061 DOI: 10.1038/S41467-020-15687-X |
0.773 |
|
| 2020 |
Lee HN, Mehta S, Zhang J. Recent advances in the use of genetically encodable optical tools to elicit and monitor signaling events. Current Opinion in Cell Biology. 63: 114-124. PMID 32058267 DOI: 10.1016/J.Ceb.2020.01.007 |
0.451 |
|
| 2020 |
Chan TO, Armen RS, Yadav S, Shah S, Zhang J, Tiegs BC, Keny N, Blumhof B, Deshpande DA, Rodeck U, Penn RB. A tripartite cooperative mechanism confers resistance of the protein kinase A catalytic subunit to dephosphorylation. The Journal of Biological Chemistry. PMID 31964716 DOI: 10.1074/Jbc.Ra119.010004 |
0.372 |
|
| 2020 |
Schmitt DL, Mehta S, Zhang J. Illuminating the kinome: Visualizing real-time kinase activity in biological systems using genetically encoded fluorescent protein-based biosensors. Current Opinion in Chemical Biology. 54: 63-69. PMID 31911398 DOI: 10.1016/J.Cbpa.2019.11.005 |
0.83 |
|
| 2020 |
Keyes J, Ganesan A, Molinar-Inglis O, Hamidzadeh A, Zhang J, Ling M, Trejo J, Levchenko A, Zhang J. Author response: Signaling diversity enabled by Rap1-regulated plasma membrane ERK with distinct temporal dynamics Elife. DOI: 10.7554/Elife.57410.Sa2 |
0.384 |
|
| 2020 |
Kwon Y, Clark MJ, Keyes J, Walters G, Sunahara RK, Zhang J. Spatiotemporal Control of ERK Activity by b
2
‐adrenergic Signaling The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.07537 |
0.369 |
|
| 2020 |
Zhong Y, Zhou X, Guan K, Zhang J. Constitutively Active Rheb Regulates Nuclear mTORC1 Activity and Function The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.07130 |
0.366 |
|
| 2020 |
Lin W, Phatarphekar A, Greenwald EC, Zhang J. A Light‐gated Integrator for Imaging Kinase Activity in Living Cells The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05541 |
0.779 |
|
| 2020 |
Zhou X, Zhong Y, Kunkel MT, Newton AC, Zhang J. Tracking mTORC1 Activity in the Nucleus: Distinct Regulation Revealed by Locationspecific Inhibition of Akt The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04692 |
0.358 |
|
| 2020 |
Garcia A, Molinar-Inglis O, Nicholas D, Keyes J, Adame J, Cisneros M, Lawson M, Zhang J, Trejo J. Improved fractionation method demonstrates phosphorylated Akt is localized to the cytoplasm in LβT2 cells The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04608 |
0.381 |
|
| 2020 |
Mehta S, Zhang J, Liu B, Hong I, Tenner B, Lin W, Huganir RL, Zhang J. An Ultrasensitive Fluorescent Biosensor for Multi‐modal Kinase Activity Detection and High‐resolution Imaging in Awake Mice The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04082 |
0.397 |
|
| 2020 |
Zhang JZ, Lu T, Tenner B, Yang J, Zhang J, Taylor S, Mehta S, Zhang J. PKA RIα phase separation drives cAMP compartmentation and suppresses tumorigenic signaling The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03204 |
0.355 |
|
| 2020 |
Schmitt DL, Zhang J, Chen M, Leung A, He CY, Curtis SD, Mehta S, Shaw RJ, Rangamani P, Zhang J. Illuminating Spatiotemporal Regulation of AMPK with a Genetically Encoded Excitation‐Ratiometric Biosensor for AMPK The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03063 |
0.678 |
|
| 2020 |
Keyes J, Ganesan A, Molinar-Inglis O, Hamidzadeh A, Ling M, Trejo J, Levchenko A, Zhang J. Signaling Diversity Enabled by Rap1 and cAMP/PKA‐Regulated Plasma Membrane ERK with Distinct Temporal Dynamics The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.00680 |
0.384 |
|
| 2020 |
Zhang J. Illuminating the Biochemical Activity Architecture of the Cell The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.00385 |
0.356 |
|
| 2019 |
Qin Q, Laub S, Shi Y, Ouyang M, Peng Q, Zhang J, Wang Y, Lu S. for Ratiometric and High-Throughput Live-Cell Image Visualization and Quantitation. Frontiers in Physics. 7. PMID 33163483 DOI: 10.3389/Fphy.2019.00154 |
0.414 |
|
| 2019 |
Hertel F, Li S, Chen M, Pott L, Mehta S, Zhang J. Fluorescent biosensors for multiplexed imaging of phosphoinositide dynamics. Acs Chemical Biology. PMID 31855412 DOI: 10.1021/Acschembio.9B00691 |
0.475 |
|
| 2019 |
Ohadi D, Schmitt DL, Calabrese B, Halpain S, Zhang J, Rangamani P. Computational Modeling Reveals Frequency Modulation of Calcium-cAMP/PKA Pathway in Dendritic Spines. Biophysical Journal. PMID 31668749 DOI: 10.1016/J.Bpj.2019.10.003 |
0.785 |
|
| 2019 |
Lin W, Mehta S, Zhang J. Genetically encoded fluorescent biosensors illuminate kinase signaling in cancer. The Journal of Biological Chemistry. PMID 31434714 DOI: 10.1074/Jbc.Rev119.006177 |
0.515 |
|
| 2019 |
Ross B, Wong SH, Snell NE, Zhang J, Rizzo MA. Triple Fluorescence Anisotropy Reporter Imaging in Living Cells. Bio-Protocol. 9. PMID 31423459 DOI: 10.21769/BioProtoc.3226 |
0.335 |
|
| 2019 |
Clister T, Greenwald EC, Baillie GS, Zhang J. AKAP95 Organizes a Nuclear Microdomain to Control Local cAMP for Regulating Nuclear PKA. Cell Chemical Biology. PMID 30982750 DOI: 10.1016/J.Chembiol.2019.03.003 |
0.785 |
|
| 2019 |
He M, Huang TS, Li S, Hong HC, Chen Z, Martin M, Zhou X, Huang HY, Su SH, Zhang J, Wang WT, Kang J, Huang HD, Zhang J, Chien S, et al. Atheroprotective Flow Upregulates ITPR3 (Inositol 1,4,5-Trisphosphate Receptor 3) in Vascular Endothelium via KLF4 (Krüppel-Like Factor 4)-Mediated Histone Modifications. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA118312301. PMID 30917677 DOI: 10.1161/Atvbaha.118.312301 |
0.303 |
|
| 2019 |
Qian Y, Piatkevich KD, Mc Larney B, Abdelfattah AS, Mehta S, Murdock MH, Gottschalk S, Molina RS, Zhang W, Chen Y, Wu J, Drobizhev M, Hughes TE, Zhang J, Schreiter ER, et al. A genetically encoded near-infrared fluorescent calcium ion indicator. Nature Methods. PMID 30664778 DOI: 10.1038/S41592-018-0294-6 |
0.496 |
|
| 2018 |
Greenwald EC, Mehta S, Zhang J. Genetically Encoded Fluorescent Biosensors Illuminate the Spatiotemporal Regulation of Signaling Networks. Chemical Reviews. PMID 30550275 DOI: 10.1021/Acs.Chemrev.8B00333 |
0.788 |
|
| 2018 |
Mehta S, Zhang Y, Roth RH, Zhang JF, Mo A, Tenner B, Huganir RL, Zhang J. Single-fluorophore biosensors for sensitive and multiplexed detection of signalling activities. Nature Cell Biology. 20: 1215-1225. PMID 30250062 DOI: 10.1038/S41556-018-0200-6 |
0.475 |
|
| 2018 |
Grimsey NJ, Narala R, Rada CC, Mehta S, Stephens BS, Kufareva I, Lapek J, Gonzalez DJ, Handel TM, Zhang J, Trejo J. A Tyrosine Switch on NEDD4-2 E3 Ligase Transmits GPCR Inflammatory Signaling. Cell Reports. 24: 3312-3323.e5. PMID 30232011 DOI: 10.1016/J.Celrep.2018.08.061 |
0.448 |
|
| 2018 |
Liu SL, Wang ZG, Hu Y, Xin Y, Singaram I, Gorai S, Zhou X, Shim Y, Min JH, Gong LW, Hay N, Zhang J, Cho W. Quantitative Lipid Imaging Reveals a New Signaling Function of Phosphatidylinositol-3,4-Bisphophate: Isoform- and Site-Specific Activation of Akt. Molecular Cell. PMID 30174291 DOI: 10.1016/J.Molcel.2018.07.035 |
0.493 |
|
| 2018 |
Zhang J, Liu J, Ren L, Wei J, Zhang F, Li Y, Guo C, Duan J, Sun Z, Zhou X. Silica nanoparticles induce abnormal mitosis and apoptosis via PKC-δ mediated negative signaling pathway in GC-2 cells of mice. Chemosphere. 208: 942-950. PMID 30068038 DOI: 10.1016/j.chemosphere.2018.05.178 |
0.301 |
|
| 2018 |
Ross BL, Tenner B, Markwardt ML, Zviman A, Shi G, Kerr JP, Snell NE, McFarland JJ, Mauban JR, Ward CW, Rizzo MA, Zhang J. Single-color, ratiometric biosensors for detecting signaling activities in live cells. Elife. 7. PMID 29968564 DOI: 10.7554/Elife.35458 |
0.459 |
|
| 2018 |
Hertel F, Mo GCH, Dedecker P, Zhang J. Observing the Assembly of Protein Complexes in Living Eukaryotic Cells in Super-Resolution Using refSOFI. Methods in Molecular Biology (Clifton, N.J.). 1764: 267-277. PMID 29605920 DOI: 10.1007/978-1-4939-7759-8_16 |
0.36 |
|
| 2018 |
Oldach LM, Gorshkov K, Mills WT, Zhang J, Meffert MK. A Biosensor for MAPK-Dependent Lin28 Signaling. Molecular Biology of the Cell. PMID 29540527 DOI: 10.1091/Mbc.E17-08-0500 |
0.469 |
|
| 2018 |
Ross BL, Tenner B, Markwardt ML, Zviman A, Shi G, Kerr JP, Snell NE, McFarland JJ, Mauban JR, Ward CW, Rizzo MA, Zhang J. Author response: Single-color, ratiometric biosensors for detecting signaling activities in live cells Elife. DOI: 10.7554/Elife.35458.037 |
0.396 |
|
| 2018 |
Zhang J. Illuminating the Biochemical Activity Architecture of the Cell Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.2223 |
0.356 |
|
| 2017 |
Nygren PJ, Mehta S, Schweppe DK, Langeberg LK, Whiting JL, Weisbrod CR, Bruce JE, Zhang J, Veesler D, Scott JD. Intrinsic disorder within AKAP79 fine-tunes anchored phosphatase activity toward substrates and drug sensitivity. Elife. 6. PMID 28967377 DOI: 10.7554/Elife.30872 |
0.368 |
|
| 2017 |
Chen Y, Booth C, Wang H, Wang R, Terzi D, Zachariou V, Jiao K, Zhang J, Wang Q. Effective attenuation of adenosine A1R signaling by neurabin requires oligomerization of neurabin. Molecular Pharmacology. PMID 28954816 DOI: 10.1124/Mol.117.109462 |
0.396 |
|
| 2017 |
Mehta S, Zhang J. Illuminating the cell's biochemical activity architecture. Biochemistry. PMID 28718621 DOI: 10.1021/Acs.Biochem.7B00561 |
0.432 |
|
| 2017 |
Ni Q, Mehta S, Zhang J. Live-cell imaging of cell signaling using genetically encoded fluorescent reporters. The Febs Journal. PMID 28613457 DOI: 10.1111/Febs.14134 |
0.485 |
|
| 2017 |
Newman RH, Zhang J. Integrated Strategies to Gain a Systems-Level View of Dynamic Signaling Networks. Methods in Enzymology. 589: 133-170. PMID 28336062 DOI: 10.1016/Bs.Mie.2017.01.016 |
0.401 |
|
| 2017 |
Mo GC, Ross B, Hertel F, Manna P, Yang X, Greenwald E, Booth C, Plummer AM, Tenner B, Chen Z, Wang Y, Kennedy EJ, Cole PA, Fleming KG, Palmer A, ... Zhang J, et al. Genetically encoded biosensors for visualizing live-cell biochemical activity at super-resolution. Nature Methods. PMID 28288122 DOI: 10.1038/Nmeth.4221 |
0.836 |
|
| 2017 |
Gorshkov K, Mehta S, Ramamurthy S, Ronnett GV, Zhou FQ, Zhang J. AKAP-mediated feedback control of cAMP gradients in developing hippocampal neurons. Nature Chemical Biology. PMID 28192412 DOI: 10.1038/Nchembio.2298 |
0.368 |
|
| 2016 |
Zhou X, Li S, Zhang J. Tracking the Activity of mTORC1 in Living Cells Using Genetically Encoded FRET-based Biosensor TORCAR. Current Protocols in Chemical Biology. 8: 225-233. PMID 27925667 DOI: 10.1002/Cpch.11 |
0.505 |
|
| 2016 |
Rodriguez EA, Campbell RE, Lin JY, Lin MZ, Miyawaki A, Palmer AE, Shu X, Zhang J, Tsien RY. The Growing and Glowing Toolbox of Fluorescent and Photoactive Proteins. Trends in Biochemical Sciences. PMID 27814948 DOI: 10.1016/J.Tibs.2016.09.010 |
0.772 |
|
| 2016 |
Moore BS, Stepanchick AN, Tewson PH, Hartle CM, Zhang J, Quinn AM, Hughes TE, Mirshahi T. Cilia have high cAMP levels that are inhibited by Sonic Hedgehog-regulated calcium dynamics. Proceedings of the National Academy of Sciences of the United States of America. PMID 27799542 DOI: 10.1073/Pnas.1602393113 |
0.506 |
|
| 2016 |
Zhang J, Gao G, Begum G, Wang J, Khanna AR, Shmukler BE, Daubner GM, de Los Heros P, Davies P, Varghese J, Bhuiyan MI, Duan J, Zhang J, Duran D, Alper SL, et al. Functional kinomics establishes a critical node of volume-sensitive cation-Cl(-) cotransporter regulation in the mammalian brain. Scientific Reports. 6: 35986. PMID 27782176 DOI: 10.1038/Srep35986 |
0.324 |
|
| 2016 |
Behar J, Ganesan A, Zhang J, Yaniv Y. The Autonomic Nervous System Regulates the Heart Rate through cAMP-PKA Dependent and Independent Coupled-Clock Pacemaker Cell Mechanisms. Frontiers in Physiology. 7: 419. PMID 27729868 DOI: 10.3389/Fphys.2016.00419 |
0.405 |
|
| 2016 |
Palmer AE, Zhang J. Roger Y. Tsien 1952-2016. Nature Chemical Biology. PMID 27669418 DOI: 10.1038/Nchembio.2213 |
0.543 |
|
| 2016 |
Conlon P, Gelin-Licht R, Ganesan A, Zhang J, Levchenko A. Single-cell dynamics and variability of MAPK activity in a yeast differentiation pathway. Proceedings of the National Academy of Sciences of the United States of America. PMID 27651485 DOI: 10.1073/Pnas.1610081113 |
0.46 |
|
| 2016 |
Ross B, Mehta S, Zhang J. Molecular tools for acute spatiotemporal manipulation of signal transduction. Current Opinion in Chemical Biology. 34: 135-142. PMID 27639090 DOI: 10.1016/J.Cbpa.2016.08.012 |
0.422 |
|
| 2016 |
Tenner B, Mehta S, Zhang J. Optical sensors to gain mechanistic insights into signaling assemblies. Current Opinion in Structural Biology. 41: 203-210. PMID 27611602 DOI: 10.1016/J.Sbi.2016.07.021 |
0.41 |
|
| 2016 |
Hung WC, Yang JR, Yankaskas CL, Wong BS, Wu PH, Pardo-Pastor C, Serra SA, Chiang MJ, Gu Z, Wirtz D, Valverde MA, Yang JT, Zhang J, Konstantopoulos K. Confinement-Sensing and Signal Optimization via Piezo1/PKA and Myosin II Pathways. Cell Reports. PMID 27160899 DOI: 10.1016/J.Celrep.2016.04.035 |
0.435 |
|
| 2016 |
Hertel F, Zhang J. Monitoring of post-translational modification dynamics with genetically encoded fluorescent reporters. Biopolymers. 101: 180-7. PMID 23576192 DOI: 10.1002/bip.22254 |
0.337 |
|
| 2016 |
Hertel F, Zhang J. A New Class of Targetable, Genetically Encoded Single-Color Biosensors for Multiplexed Monitoring of Phosphoinositides Biophysical Journal. 110: 336. DOI: 10.1016/J.Bpj.2015.11.1809 |
0.426 |
|
| 2015 |
Hertel F, Mo GC, Duwé S, Dedecker P, Zhang J. RefSOFI for Mapping Nanoscale Organization of Protein-Protein Interactions in Living Cells. Cell Reports. PMID 26748717 DOI: 10.1016/J.Celrep.2015.12.036 |
0.367 |
|
| 2015 |
Head SA, Shi W, Zhao L, Gorshkov K, Pasunooti K, Chen Y, Deng Z, Li RJ, Shim JS, Tan W, Hartung T, Zhang J, Zhao Y, Colombini M, Liu JO. Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 26655341 DOI: 10.1073/Pnas.1512867112 |
0.408 |
|
| 2015 |
Depry C, Mehta S, Li R, Zhang J. Visualization of Compartmentalized Kinase Activity Dynamics Using Adaptable BimKARs. Chemistry & Biology. PMID 26548610 DOI: 10.1016/J.Chembiol.2015.10.004 |
0.831 |
|
| 2015 |
Hu J, Neiswinger J, Zhang J, Zhu H, Qian J. Systematic Prediction of Scaffold Proteins Reveals New Design Principles in Scaffold-Mediated Signal Transduction. Plos Computational Biology. 11: e1004508. PMID 26393507 DOI: 10.1371/Journal.Pcbi.1004508 |
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| 2015 |
Yaniv Y, Ganesan A, Yang D, Ziman BD, Lyashkov AE, Levchenko A, Zhang J, Lakatta EG. Real-time relationship between PKA biochemical signal network dynamics and increased action potential firing rate in heart pacemaker cells: Yaniv. Kinetics of PKA activation in heart pacemaker cells. Journal of Molecular and Cellular Cardiology. PMID 26241846 DOI: 10.1016/J.Yjmcc.2015.07.024 |
0.405 |
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| 2015 |
Chan TO, Zhang J, Tiegs BC, Blumhof B, Yan L, Keny N, Penny M, Li X, Pascal JM, Armen RS, Rodeck U, Penn RB. Akt Kinase C-Terminal Modifications Control Activation Loop Dephosphorylation and Enhance Insulin Response. The Biochemical Journal. PMID 26201515 DOI: 10.1042/Bj20150325 |
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| 2015 |
Karlsson I, Zhou X, Thomas R, Smith AT, Bonner MY, Bakshi P, Banga AK, Bowen JP, Qabaja G, Ford SL, Ballard MD, Petersen KS, Li X, Chen G, Ogretmen B, ... Zhang J, et al. Solenopsin A and analogs exhibit ceramide-like biological activity. Vascular Cell. 7: 5. PMID 26015865 DOI: 10.1186/S13221-015-0030-2 |
0.383 |
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| 2015 |
Mehta S, Zhang J. Light moves mountains in the cell. Chemistry & Biology. 22: 569-70. PMID 26000746 DOI: 10.1016/J.Chembiol.2015.05.002 |
0.329 |
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| 2015 |
Miyamoto T, Rho E, Sample V, Akano H, Magari M, Ueno T, Gorshkov K, Chen M, Tokumitsu H, Zhang J, Inoue T. Compartmentalized AMPK signaling illuminated by genetically encoded molecular sensors and actuators. Cell Reports. 11: 657-70. PMID 25892241 DOI: 10.1016/J.Celrep.2015.03.057 |
0.829 |
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| 2015 |
Sample V, Ramamurthy S, Gorshkov K, Ronnett GV, Zhang J. Polarized activities of AMPK and BRSK in primary hippocampal neurons. Molecular Biology of the Cell. 26: 1935-46. PMID 25788287 DOI: 10.1091/Mbc.E14-02-0764 |
0.783 |
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| 2015 |
Zhou X, Clister TL, Lowry PR, Seldin MM, Wong GW, Zhang J. Dynamic Visualization of mTORC1 Activity in Living Cells. Cell Reports. PMID 25772363 DOI: 10.1016/J.Celrep.2015.02.031 |
0.465 |
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| 2015 |
Mehta S, Zhang J. Dynamic visualization of calcium-dependent signaling in cellular microdomains. Cell Calcium. PMID 25703691 DOI: 10.1016/J.Ceca.2015.01.009 |
0.416 |
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| 2015 |
Ding Y, Li J, Enterina JR, Shen Y, Zhang I, Tewson PH, Mo GC, Zhang J, Quinn AM, Hughes TE, Maysinger D, Alford SC, Zhang Y, Campbell RE. Ratiometric biosensors based on dimerization-dependent fluorescent protein exchange. Nature Methods. 12: 195-8. PMID 25622108 DOI: 10.1038/Nmeth.3261 |
0.677 |
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| 2015 |
Clister T, Mehta S, Zhang J. Single-cell analysis of G-protein signal transduction. The Journal of Biological Chemistry. 290: 6681-8. PMID 25605723 DOI: 10.1074/Jbc.R114.616391 |
0.463 |
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| 2015 |
Dou H, Wang C, Wu X, Yao L, Zhang X, Teng S, Xu H, Liu B, Wu Q, Zhang Q, Hu M, Wang Y, Wang L, Wu Y, Shang S, ... Zhang J, et al. Calcium influx activates adenylyl cyclase 8 for sustained insulin secretion in rat pancreatic beta cells. Diabetologia. 58: 324-33. PMID 25381556 DOI: 10.1007/S00125-014-3437-Z |
0.352 |
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| 2015 |
Zhang J. Compartmentalized PI3K/Akt/mTOR Signaling in Living Cells The Faseb Journal. 29. DOI: 10.1096/Fasebj.29.1_Supplement.234.3 |
0.439 |
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| 2015 |
Hertel F, Mo G, Duwé S, Dedecker P, Zhang J. Refsofi for Imaging Protein-Protein Interactions in Living Cells in Super-Resolution Biophysical Journal. 108: 360. DOI: 10.1016/J.Bpj.2014.11.1977 |
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| 2015 |
Mo GCH, Zhang J. A Novel Molecular Ruler between Fluorescent Proteins Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.1895 |
0.5 |
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| 2014 |
Gorshkov K, Zhang J. Visualization of cyclic nucleotide dynamics in neurons. Frontiers in Cellular Neuroscience. 8: 395. PMID 25538560 DOI: 10.3389/Fncel.2014.00395 |
0.458 |
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| 2014 |
Newman RH, Zhang J, Zhu H. Toward a systems-level view of dynamic phosphorylation networks. Frontiers in Genetics. 5: 263. PMID 25177341 DOI: 10.3389/Fgene.2014.00263 |
0.47 |
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| 2014 |
Mehta S, Aye-Han NN, Ganesan A, Oldach L, Gorshkov K, Zhang J. Calmodulin-controlled spatial decoding of oscillatory Ca2+ signals by calcineurin. Elife. 3: e03765. PMID 25056880 DOI: 10.7554/Elife.03765 |
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| 2014 |
Kim TJ, Sun J, Lu S, Zhang J, Wang Y. The regulation of β-adrenergic receptor-mediated PKA activation by substrate stiffness via microtubule dynamics in human MSCs. Biomaterials. 35: 8348-56. PMID 24973298 DOI: 10.1016/J.Biomaterials.2014.06.018 |
0.417 |
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| 2014 |
Fu Q, Kim S, Soto D, De Arcangelis V, DiPilato L, Liu S, Xu B, Shi Q, Zhang J, Xiang YK. A long lasting β1 adrenergic receptor stimulation of cAMP/protein kinase A (PKA) signal in cardiac myocytes. The Journal of Biological Chemistry. 289: 14771-81. PMID 24713698 DOI: 10.1074/Jbc.M113.542589 |
0.811 |
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| 2014 |
Sample V, Mehta S, Zhang J. Genetically encoded molecular probes to visualize and perturb signaling dynamics in living biological systems. Journal of Cell Science. 127: 1151-60. PMID 24634506 DOI: 10.1242/Jcs.099994 |
0.806 |
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| 2014 |
Haj Slimane Z, Bedioune I, Lechêne P, Varin A, Lefebvre F, Mateo P, Domergue-Dupont V, Dewenter M, Richter W, Conti M, El-Armouche A, Zhang J, Fischmeister R, Vandecasteele G. Control of cytoplasmic and nuclear protein kinase A by phosphodiesterases and phosphatases in cardiac myocytes. Cardiovascular Research. 102: 97-106. PMID 24550350 DOI: 10.1093/Cvr/Cvu029 |
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| 2014 |
Oldach L, Zhang J. Genetically encoded fluorescent biosensors for live-cell visualization of protein phosphorylation Chemistry and Biology. 21: 186-197. PMID 24485761 DOI: 10.1016/J.Chembiol.2013.12.012 |
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| 2014 |
Wang Y, Ho TG, Bertinetti D, Neddermann M, Franz E, Mo GC, Schendowich LP, Sukhu A, Spelts RC, Zhang J, Herberg FW, Kennedy EJ. Isoform-selective disruption of AKAP-localized PKA using hydrocarbon stapled peptides. Acs Chemical Biology. 9: 635-42. PMID 24422448 DOI: 10.1021/Cb400900R |
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| 2014 |
Hu J, Rho HS, Newman RH, Zhang J, Zhu H, Qian J. PhosphoNetworks: a database for human phosphorylation networks. Bioinformatics (Oxford, England). 30: 141-2. PMID 24227675 DOI: 10.1093/Bioinformatics/Btt627 |
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| 2014 |
Cazabat L, Ragazzon B, Varin A, Potier-Cartereau M, Vandier C, Vezzosi D, Risk-Rabin M, Guellich A, Schittl J, Lechêne P, Richter W, Nikolaev VO, Zhang J, Bertherat J, Vandecasteele G. Inactivation of the Carney complex gene 1 (PRKAR1A) alters spatiotemporal regulation of cAMP and cAMP-dependent protein kinase: a study using genetically encoded FRET-based reporters. Human Molecular Genetics. 23: 1163-74. PMID 24122441 DOI: 10.1093/Hmg/Ddt510 |
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| 2014 |
Robinson KH, Yang JR, Zhang J. FRET and BRET-based biosensors in live cell compound screens. Methods in Molecular Biology (Clifton, N.J.). 1071: 217-25. PMID 24052392 DOI: 10.1007/978-1-62703-622-1_17 |
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| 2014 |
Aye-Han NN, Zhang J. A multiparameter live cell imaging approach to monitor cyclic AMP and protein kinase A dynamics in parallel. Methods in Molecular Biology (Clifton, N.J.). 1071: 207-15. PMID 24052391 DOI: 10.1007/978-1-62703-622-1_16 |
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| 2014 |
Aye-Han NN, Zhang J. A multiparameter live cell imaging approach to monitor cyclic AMP and protein kinase A dynamics in parallel. Methods in Molecular Biology (Clifton, N.J.). 1071: 207-15. PMID 24052391 DOI: 10.1007/978-1-62703-622-1_16 |
0.437 |
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| 2014 |
Mehta S, Zhang J. Using a genetically encoded FRET-based reporter to visualize calcineurin phosphatase activity in living cells. Methods in Molecular Biology (Clifton, N.J.). 1071: 139-49. PMID 24052386 DOI: 10.1007/978-1-62703-622-1_11 |
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| 2014 |
Newman RH, Zhang J. The design and application of genetically encodable biosensors based on fluorescent proteins. Methods in Molecular Biology (Clifton, N.J.). 1071: 1-16. PMID 24052376 DOI: 10.1007/978-1-62703-622-1_1 |
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| 2014 |
Hu J, Rho HS, Newman RH, Hwang W, Neiswinger J, Zhu H, Zhang J, Qian J. Global analysis of phosphorylation networks in humans. Biochimica Et Biophysica Acta. 1844: 224-31. PMID 23524292 DOI: 10.1016/J.Bbapap.2013.03.009 |
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| 2014 |
Mehta S, Aye-Han N, Ganesan A, Oldach L, Gorshkov K, Zhang J. Author response: Calmodulin-controlled spatial decoding of oscillatory Ca2+ signals by calcineurin Elife. DOI: 10.7554/Elife.03765.018 |
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| 2014 |
Mo G, Zhang J. Mute-Kars: Silent Kinase Activity Reporters Useful for Co-Imaging Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.4443 |
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| 2014 |
Ross BL, Zhang J. Superresolution Plasmalemmal Lipid Mapping Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.1756 |
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| 2014 |
Zhang J. Probing Spatiotemporal Regulation of Signal Transduction in Living Cells Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.080 |
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| 2014 |
Hertel F, Zhang J. Monitoring of post-translational modification dynamics with genetically encoded fluorescent reporters Biopolymers. 101: 180-187. DOI: 10.1002/Bip.22254 |
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| 2013 |
Mehta S, Zhang J. Using a kinase-inducible bimolecular switch to control enzyme activity in living cells. Current Protocols in Chemical Biology. 5: 227-37. PMID 24391085 DOI: 10.1002/9780470559277.Ch130090 |
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| 2013 |
Woodard CL, Goodwin CR, Wan J, Xia S, Newman R, Hu J, Zhang J, Hayward SD, Qian J, Laterra J, Zhu H. Profiling the dynamics of a human phosphorylome reveals new components in HGF/c-Met signaling. Plos One. 8: e72671. PMID 24023761 DOI: 10.1371/Journal.Pone.0072671 |
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| 2013 |
Zhang J, Gao Z, Ye J. Phosphorylation and degradation of S6K1 (p70S6K1) in response to persistent JNK1 Activation. Biochimica Et Biophysica Acta. 1832: 1980-8. PMID 23816567 DOI: 10.1016/j.bbadis.2013.06.013 |
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| 2013 |
Burdyga A, Conant A, Haynes L, Zhang J, Jalink K, Sutton R, Neoptolemos J, Costello E, Tepikin A. cAMP inhibits migration, ruffling and paxillin accumulation in focal adhesions of pancreatic ductal adenocarcinoma cells: effects of PKA and EPAC. Biochimica Et Biophysica Acta. 1833: 2664-72. PMID 23797058 DOI: 10.1016/j.bbamcr.2013.06.011 |
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| 2013 |
Nunes AR, Holmes AP, Sample V, Kumar P, Cann MJ, Monteiro EC, Zhang J, Gauda EB. Bicarbonate-sensitive soluble and transmembrane adenylyl cyclases in peripheral chemoreceptors. Respiratory Physiology & Neurobiology. 188: 83-93. PMID 23727159 DOI: 10.1016/J.Resp.2013.05.013 |
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| 2013 |
Huang J, Yang JR, Zhang J, Yang J. Total synthesis and structure-activity relationship study of the potent cAMP signaling agonist (-)-alotaketal A. Organic & Biomolecular Chemistry. 11: 3212-22. PMID 23584129 DOI: 10.1039/C3Ob40120K |
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| 2013 |
Newman RH, Hu J, Rho HS, Xie Z, Woodard C, Neiswinger J, Cooper C, Shirley M, Clark HM, Hu S, Hwang W, Jeong JS, Wu G, Lin J, Gao X, ... ... Zhang J, et al. Construction of human activity-based phosphorylation networks. Molecular Systems Biology. 9: 655. PMID 23549483 DOI: 10.1038/Msb.2013.12 |
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| 2013 |
Depry C, Mehta S, Zhang J. Multiplexed visualization of dynamic signaling networks using genetically encoded fluorescent protein-based biosensors Pflugers Archiv European Journal of Physiology. 465: 373-381. PMID 23138230 DOI: 10.1007/S00424-012-1175-Y |
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| 2013 |
Sample V, Ni Q, Mehta S, Inoue T, Zhang J. Controlling enzymatic action in living cells with a kinase-inducible bimolecular switch Acs Chemical Biology. 8: 116-121. PMID 23072367 DOI: 10.1021/Cb300393W |
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| 2013 |
Sample V, DiPilato LM, Yang JH, Ni Q, Saucerman JJ, Zhang J. Erratum: Corrigendum: Regulation of nuclear PKA revealed by spatiotemporal manipulation of cyclic AMP Nature Chemical Biology. 9: 406-406. DOI: 10.1038/Nchembio0613-406B |
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| 2012 |
Nunes AR, Sample V, Xiang YK, Monteiro EC, Gauda E, Zhang J. Effect of oxygen on phosphodiesterases (PDE) 3 and 4 isoforms and PKA activity in the superior cervical ganglia Advances in Experimental Medicine and Biology. 758: 287-294. PMID 23080174 DOI: 10.1007/978-94-007-4584-1_39 |
0.815 |
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| 2012 |
Ghigo A, Perino A, Mehel H, Zahradníková A, Morello F, Leroy J, Nikolaev VO, Damilano F, Cimino J, De Luca E, Richter W, Westenbroek R, Catterall WA, Zhang J, Yan C, et al. Phosphoinositide 3-kinase γ protects against catecholamine-induced ventricular arrhythmia through protein kinase A-mediated regulation of distinct phosphodiesterases. Circulation. 126: 2073-83. PMID 23008439 DOI: 10.1161/Circulationaha.112.114074 |
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| 2012 |
Dedecker P, Mo GC, Dertinger T, Zhang J. Widely accessible method for superresolution fluorescence imaging of living systems. Proceedings of the National Academy of Sciences of the United States of America. 109: 10909-14. PMID 22711840 DOI: 10.1073/Pnas.1204917109 |
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| 2012 |
Ganesan A, Zhang J. How cells process information: quantification of spatiotemporal signaling dynamics. Protein Science : a Publication of the Protein Society. 21: 918-28. PMID 22573643 DOI: 10.1002/Pro.2089 |
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| 2012 |
Huang J, Yang JR, Zhang J, Yang J. Total synthesis of the potent cAMP signaling agonist (-)-alotaketal A. Journal of the American Chemical Society. 134: 8806-9. PMID 22563931 DOI: 10.1021/Ja303529Z |
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| 2012 |
Ferrando IM, Chaerkady R, Zhong J, Molina H, Jacob HK, Herbst-Robinson K, Dancy BM, Katju V, Bose R, Zhang J, Pandey A, Cole PA. Identification of targets of c-Src tyrosine kinase by chemical complementation and phosphoproteomics. Molecular & Cellular Proteomics : McP. 11: 355-69. PMID 22499769 DOI: 10.1074/Mcp.M111.015750 |
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| 2012 |
Sample V, DiPilato LM, Yang JH, Ni Q, Saucerman JJ, Zhang J. Regulation of nuclear PKA revealed by spatiotemporal manipulation of cyclic AMP. Nature Chemical Biology. 8: 375-82. PMID 22366721 DOI: 10.1038/Nchembio.799 |
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| 2012 |
Aye-Han NN, Allen MD, Ni Q, Zhang J. Parallel tracking of cAMP and PKA signaling dynamics in living cells with FRET-based fluorescent biosensors. Molecular Biosystems. 8: 1435-40. PMID 22362165 DOI: 10.1039/C2Mb05514G |
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| 2012 |
Zhou X, Herbst-Robinson KJ, Zhang J. Visualizing dynamic activities of signaling enzymes using genetically encodable FRET-based biosensors: From designs to applications Methods in Enzymology. 504: 317-340. PMID 22264542 DOI: 10.1016/B978-0-12-391857-4.00016-1 |
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| 2012 |
del Puerto A, DÃaz-Hernández JI, Tapia M, Gomez-Villafuertes R, Benitez MJ, Zhang J, Miras-Portugal MT, Wandosell F, DÃaz-Hernández M, Garrido JJ. Adenylate cyclase 5 coordinates the action of ADP, P2Y1, P2Y13 and ATP-gated P2X7 receptors on axonal elongation. Journal of Cell Science. 125: 176-88. PMID 22250198 DOI: 10.1242/Jcs.091736 |
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| 2012 |
Slimane ZH, Zhang J, Richter W, Fischmeister R, Vandecasteele G. Spatiotemporal Regulation of cAMP-Dependent Protein Kinase (PKA) in Cardiac Myocytes Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.3637 |
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| 2012 |
Ganesan A, Levchenko A, Zhang J. ERK-Mediated Decoding of Calcium Oscillations in Pancreatic Beta Cells Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.2777 |
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| 2011 |
Chan TO, Zhang J, Rodeck U, Pascal JM, Armen RS, Spring M, Dumitru CD, Myers V, Li X, Cheung JY, Feldman AM. Resistance of Akt kinases to dephosphorylation through ATP-dependent conformational plasticity Proceedings of the National Academy of Sciences of the United States of America. 108: E1120-E1127. PMID 22031698 DOI: 10.1073/Pnas.1109879108 |
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| 2011 |
Chakir K, Depry C, Dimaano VL, Zhu WZ, Vanderheyden M, Bartunek J, Abraham TP, Tomaselli GF, Liu SB, Xiang YK, Zhang M, Takimoto E, Dulin N, Xiao RP, Zhang J, et al. Galphas-biased beta2-adrenergic receptor signaling from restoring synchronous contraction in the failing heart. Science Translational Medicine. 3: 100ra88. PMID 21918105 DOI: 10.1126/Scitranslmed.3001909 |
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| 2011 |
Gao X, Lowry PR, Zhou X, Depry C, Wei Z, Wong GW, Zhang J. PI3K/Akt signaling requires spatial compartmentalization in plasma membrane microdomains. Proceedings of the National Academy of Sciences of the United States of America. 108: 14509-14. PMID 21873248 DOI: 10.1073/Pnas.1019386108 |
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| 2011 |
Depry C, Zhang J. Using FRET-based reporters to visualize subcellular dynamics of protein kinase A activity Methods in Molecular Biology. 756: 285-294. PMID 21870233 DOI: 10.1007/978-1-61779-160-4_16 |
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| 2011 |
Herbst KJ, Allen MD, Zhang J. Spatiotemporally regulated protein kinase a activity is a critical regulator of growth factor-stimulated extracellular signal-regulated kinase signaling in PC12 Cells Molecular and Cellular Biology. 31: 4063-4075. PMID 21807900 DOI: 10.1128/Mcb.05459-11 |
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| 2011 |
Mehta S, Zhang J. Reporting from the field: Genetically encoded fluorescent reporters uncover signaling dynamics in living biological systems Annual Review of Biochemistry. 80: 375-401. PMID 21495849 DOI: 10.1146/Annurev-Biochem-060409-093259 |
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| 2011 |
Newman RH, Fosbrink MD, Zhang J. Genetically encodable fluorescent biosensors for tracking signaling dynamics in living cells. Chemical Reviews. 111: 3614-66. PMID 21456512 DOI: 10.1021/Cr100002U |
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| 2011 |
Herbst KJ, Allen MD, Zhang J. Luminescent kinase activity biosensors based on a versatile bimolecular switch Journal of the American Chemical Society. 133: 5676-5679. PMID 21438554 DOI: 10.1021/Ja1117396 |
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| 2011 |
Wan M, Li J, Herbst K, Zhang J, Yu B, Wu X, Qiu T, Lei W, Lindvall C, Williams BO, Ma H, Zhang F, Cao X. LRP6 mediates cAMP generation by G protein-coupled receptors through regulating the membrane targeting of Gα(s). Science Signaling. 4: ra15. PMID 21406690 DOI: 10.1126/Scisignal.2001464 |
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| 2011 |
Herbst KJ, Coltharp C, Amzel LM, Zhang J. Direct activation of Epac by sulfonylurea is isoform selective Chemistry and Biology. 18: 243-251. PMID 21338921 DOI: 10.1016/J.Chembiol.2010.12.007 |
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| 2011 |
Liu S, Zhang J, Xiang YK. FRET-based direct detection of dynamic protein kinase A activity on the sarcoplasmic reticulum in cardiomyocytes Biochemical and Biophysical Research Communications. 404: 581-586. PMID 21130738 DOI: 10.1016/J.Bbrc.2010.11.116 |
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| 2011 |
Ni Q, Ganesan A, Aye-Han NN, Gao X, Allen MD, Levchenko A, Zhang J. Signaling diversity of PKA achieved via a Ca2+-cAMP-PKA oscillatory circuit. Nature Chemical Biology. 7: 34-40. PMID 21102470 DOI: 10.1038/Nchembio.478 |
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| 2011 |
Depry C, Allen MD, Zhang J. Visualization of PKA activity in plasma membrane microdomains. Molecular Biosystems. 7: 52-8. PMID 20838685 DOI: 10.1039/C0Mb00079E |
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| 2011 |
Gao X, Zhang J. Akt signaling dynamics in plasma membrane microdomains visualized by FRET-based reporters. Communicative & Integrative Biology. 2: 32-4. PMID 19704863 DOI: 10.4161/cib.2.1.7420 |
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| 2011 |
Ganesan A, Ni Q, Aye-Han N, Gao X, Allen MD, Levchenko A, Zhang J. PKA is a Control Node in a Calcium-Dependent Oscillatory Circuit in Pancreatic Beta Cells Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.3023 |
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| 2010 |
Gildea JJ, Shah I, Weiss R, Casscells ND, McGrath HE, Zhang J, Jones JE, Felder RA. HK-2 human renal proximal tubule cells as a model for G protein-coupled receptor kinase type 4-mediated dopamine 1 receptor uncoupling. Hypertension. 56: 505-11. PMID 20660820 DOI: 10.1161/Hypertensionaha.110.152256 |
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| 2010 |
Depry C, Zhang J. Visualization of kinase activity with FRET-based activity biosensors Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 18.15. PMID 20583095 DOI: 10.1002/0471142727.Mb1815S91 |
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| 2010 |
Fosbrink M, Aye-Han NN, Cheong R, Levchenko A, Zhang J. Visualization of JNK activity dynamics with a genetically encoded fluorescent biosensor. Proceedings of the National Academy of Sciences of the United States of America. 107: 5459-64. PMID 20212108 DOI: 10.1073/Pnas.0909671107 |
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| 2010 |
Gao X, Zhang J. FRET-based activity biosensors to probe compartmentalized signaling Chembiochem. 11: 147-151. PMID 20014085 DOI: 10.1002/Cbic.200900594 |
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| 2010 |
DiPilato LM, Zhang J. Fluorescent protein-based biosensors: resolving spatiotemporal dynamics of signaling. Current Opinion in Chemical Biology. 14: 37-42. PMID 19910237 DOI: 10.1016/J.Cbpa.2009.10.012 |
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| 2010 |
Ni Q, Zhang J. Dynamic Visualization of cellular signaling Advances in Biochemical Engineering/Biotechnology. 119: 79-97. PMID 19499207 DOI: 10.1007/10_2008_48 |
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| 2010 |
Gildea JJ, Shah I, Weiss R, Casscells ND, McGrath HE, Zhang J, Felder RA. Erratum: HK-2 human renal proximal tubule cells as a model for G protein-coupled receptor kinase type 4-mediated dopamine 1 receptor uncoupling (Hypertension (2010) 56 (505-511)) Hypertension. 56. DOI: 10.1161/Hyp.0B013E3181F914Ee |
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| 2009 |
Sample V, Newman RH, Zhang J. The structure and function of fluorescent proteins. Chemical Society Reviews. 38: 2852-64. PMID 19771332 DOI: 10.1039/B913033K |
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| 2009 |
Gildea JJ, Israel JA, Johnson AK, Zhang J, Jose PA, Felder RA. Caveolin-1 and dopamine-mediated internalization of NaKATPase in human renal proximal tubule cells. Hypertension. 54: 1070-6. PMID 19752292 DOI: 10.1161/Hypertensionaha.109.134338 |
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| 2009 |
Aye-Han NN, Ni Q, Zhang J. Fluorescent biosensors for real-time tracking of post-translational modification dynamics Current Opinion in Chemical Biology. 13: 392-397. PMID 19682946 DOI: 10.1016/J.Cbpa.2009.07.009 |
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| 2009 |
Herbst KJ, Ni Q, Zhang J. Dynamic visualization of signal transduction in living cells: From second messengers to kinases Iubmb Life. 61: 902-908. PMID 19603514 DOI: 10.1002/Iub.232 |
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| 2009 |
DiPilato LM, Zhang J. The role of membrane microdomains in shaping beta2-adrenergic receptor-mediated cAMP dynamics. Molecular Biosystems. 5: 832-7. PMID 19603118 DOI: 10.1039/B823243A |
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| 2009 |
Herbst KJ, Allen MD, Zhang J. The cAMP-dependent protein kinase inhibitor H-89 attenuates the bioluminescence signal produced by Renilla Luciferase. Plos One. 4: e5642. PMID 19461967 DOI: 10.1371/Journal.Pone.0005642 |
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| 2009 |
Zhang J. The colorful journey of green fluorescent protein Acs Chemical Biology. 4: 85-88. PMID 19228068 DOI: 10.1021/Cb900027R |
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| 2009 |
Soto D, De Arcangelis V, Zhang J, Xiang Y. Dynamic protein kinase a activities induced by beta-adrenoceptors dictate signaling propagation for substrate phosphorylation and myocyte contraction. Circulation Research. 104: 770-9. PMID 19213958 DOI: 10.1161/Circresaha.108.187880 |
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| 2009 |
Seong J, Lu S, Ouyang M, Huang H, Zhang J, Frame MC, Wang Y. Visualization of Src activity at different compartments of the plasma membrane by FRET imaging. Chemistry & Biology. 16: 48-57. PMID 19171305 DOI: 10.1016/J.Chembiol.2008.11.007 |
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| 2009 |
Rahdar M, Inoue T, Meyer T, Zhang J, Vazquez F, Devreotes PN. A phosphorylation-dependent intramolecular interaction regulates the membrane association and activity of the tumor suppressor PTEN. Proceedings of the National Academy of Sciences of the United States of America. 106: 480-5. PMID 19114656 DOI: 10.1073/Pnas.0811212106 |
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| 2008 |
Ananthanarayanan B, Ni Q, Zhang J. Chapter 2: Molecular sensors based on fluorescence resonance energy transfer to visualize cellular dynamics. Methods in Cell Biology. 89: 37-57. PMID 19118671 DOI: 10.1016/S0091-679X(08)00602-X |
0.41 |
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| 2008 |
Vincent P, Gervasi N, Zhang J. Real-time monitoring of cyclic nucleotide signaling in neurons using genetically encoded FRET probes. Brain Cell Biology. 36: 3-17. PMID 18941898 DOI: 10.1007/S11068-008-9035-6 |
0.607 |
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| 2008 |
Allen MD, DiPilato LM, Ananthanarayanan B, Newman RH, Ni Q, Zhang J. Dynamic visualization of signaling activities in living cells. Science Signaling. 1: pt6. PMID 18799423 DOI: 10.1126/Scisignal.137Pt6 |
0.847 |
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| 2008 |
Lim CJ, Kain KH, Tkachenko E, Goldfinger LE, Gutierrez E, Allen MD, Groisman A, Zhang J, Ginsberg MH. Integrin-mediated protein kinase A activation at the leading edge of migrating cells. Molecular Biology of the Cell. 19: 4930-41. PMID 18784251 DOI: 10.1091/Mbc.E08-06-0564 |
0.488 |
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| 2008 |
Szewczuk LM, Tarrant MK, Sample V, Drury WJ, Zhang J, Cole PA. Analysis of serotonin N-acetyltransferase regulation in vitro and in live cells using protein semisynthesis. Biochemistry. 47: 10407-19. PMID 18771288 DOI: 10.1021/Bi801189D |
0.821 |
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| 2008 |
Lu S, Ouyang M, Seong J, Zhang J, Chien S, Wang Y. The spatiotemporal pattern of Src activation at lipid rafts revealed by diffusion-corrected FRET imaging. Plos Computational Biology. 4: e1000127. PMID 18711637 DOI: 10.1371/Journal.Pcbi.1000127 |
0.396 |
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| 2008 |
Gao X, Zhang J. Spatiotemporal analysis of differential Akt regulation in plasma membrane microdomains Molecular Biology of the Cell. 19: 4366-4373. PMID 18701703 DOI: 10.1091/Mbc.E08-05-0449 |
0.459 |
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| 2008 |
Newman RH, Zhang J. Visualization of phosphatase activity in living cells with a FRET-based calcineurin activity sensor Molecular Biosystems. 4: 496-501. PMID 18493642 DOI: 10.1039/B720034J |
0.527 |
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| 2008 |
Violin JD, DiPilato LM, Yildirim N, Elston TC, Zhang J, Lefkowitz RJ. beta2-adrenergic receptor signaling and desensitization elucidated by quantitative modeling of real time cAMP dynamics. The Journal of Biological Chemistry. 283: 2949-61. PMID 18045878 DOI: 10.1074/Jbc.M707009200 |
0.809 |
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| 2008 |
Ni Q, Fosbrink M, Zhang J. Illuminating the phosphatidylinositol 3-kinase/Akt pathway Progress in Biomedical Optics and Imaging - Proceedings of Spie. 6868. DOI: 10.1117/12.765524 |
0.516 |
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| 2007 |
Zhang J, Allen MD. FRET-based biosensors for protein kinases: illuminating the kinome. Molecular Biosystems. 3: 759-65. PMID 17940658 DOI: 10.1039/B706628G |
0.516 |
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| 2007 |
Ananthanarayanan B, Fosbrink M, Rahdar M, Zhang J. Live-cell molecular analysis of Akt activation reveals roles for activation loop phosphorylation. The Journal of Biological Chemistry. 282: 36634-41. PMID 17928291 DOI: 10.1074/Jbc.M706227200 |
0.757 |
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| 2007 |
Sachs BD, Baillie GS, McCall JR, Passino MA, Schachtrup C, Wallace DA, Dunlop AJ, MacKenzie KF, Klussmann E, Lynch MJ, Sikorski SL, Nuriel T, Tsigelny I, Zhang J, Houslay MD, et al. p75 neurotrophin receptor regulates tissue fibrosis through inhibition of plasminogen activation via a PDE4/cAMP/PKA pathway. The Journal of Cell Biology. 177: 1119-32. PMID 17576803 DOI: 10.1083/Jcb.200701040 |
0.33 |
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| 2007 |
Maresh J, Zhang J, Tzeng YL, Goodman NA, Lynn DG. Rational design of inhibitors of VirA-VirG two-component signal transduction. Bioorganic & Medicinal Chemistry Letters. 17: 3281-6. PMID 17470391 DOI: 10.1016/J.Bmcl.2007.04.018 |
0.348 |
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| 2007 |
Gervasi N, Hepp R, Tricoire L, Zhang J, Lambolez B, Paupardin-Tritsch D, Vincent P. Dynamics of protein kinase A signaling at the membrane, in the cytosol, and in the nucleus of neurons in mouse brain slices. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 2744-50. PMID 17360896 DOI: 10.1523/Jneurosci.5352-06.2007 |
0.622 |
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| 2006 |
Allen MD, DiPilato LM, Rahdar M, Ren YR, Chong C, Liu JO, Zhang J. Reading dynamic kinase activity in living cells for high-throughput screening. Acs Chemical Biology. 1: 371-6. PMID 17163774 DOI: 10.1021/Cb600202F |
0.821 |
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| 2006 |
Maresh J, Zhang J, Lynn DG. The innate immunity of maize and the dynamic chemical strategies regulating two-component signal transduction in Agrobacterium tumefaciens. Acs Chemical Biology. 1: 165-75. PMID 17163664 DOI: 10.1021/Cb600051W |
0.3 |
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| 2006 |
Dunn TA, Wang CT, Colicos MA, Zaccolo M, DiPilato LM, Zhang J, Tsien RY, Feller MB. Imaging of cAMP levels and protein kinase A activity reveals that retinal waves drive oscillations in second-messenger cascades. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 12807-15. PMID 17151284 DOI: 10.1523/Jneurosci.3238-06.2006 |
0.814 |
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| 2006 |
DiPilato LM, Zhang J. FRETting mice shed light on cardiac adrenergic signaling. Circulation Research. 99: 1021-3. PMID 17095728 DOI: 10.1161/01.Res.0000250962.61995.Cf |
0.826 |
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| 2006 |
Ni Q, Titov DV, Zhang J. Analyzing protein kinase dynamics in living cells with FRET reporters. Methods (San Diego, Calif.). 40: 279-86. PMID 16908183 DOI: 10.1016/J.Ymeth.2006.06.013 |
0.515 |
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| 2006 |
Saucerman JJ, Zhang J, Martin JC, Peng LX, Stenbit AE, Tsien RY, McCulloch AD. Systems analysis of PKA-mediated phosphorylation gradients in live cardiac myocytes. Proceedings of the National Academy of Sciences of the United States of America. 103: 12923-8. PMID 16905651 DOI: 10.1073/Pnas.0600137103 |
0.777 |
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| 2006 |
Allen MD, Zhang J. Subcellular dynamics of protein kinase A activity visualized by FRET-based reporters. Biochemical and Biophysical Research Communications. 348: 716-21. PMID 16895723 DOI: 10.1016/J.Bbrc.2006.07.136 |
0.52 |
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| 2006 |
Qiao Y, Molina H, Pandey A, Zhang J, Cole PA. Chemical rescue of a mutant enzyme in living cells. Science (New York, N.Y.). 311: 1293-7. PMID 16513984 DOI: 10.1126/Science.1122224 |
0.469 |
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| 2005 |
Ananthanarayanan B, Ni Q, Zhang J. Signal propagation from membrane messengers to nuclear effectors revealed by reporters of phosphoinositide dynamics and Akt activity. Proceedings of the National Academy of Sciences of the United States of America. 102: 15081-6. PMID 16214892 DOI: 10.1073/Pnas.0502889102 |
0.471 |
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| 2005 |
Zhang J, Hupfeld CJ, Taylor SS, Olefsky JM, Tsien RY. Insulin disrupts beta-adrenergic signalling to protein kinase A in adipocytes. Nature. 437: 569-73. PMID 16177793 DOI: 10.1038/Nature04140 |
0.604 |
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| 2005 |
Kunkel MT, Ni Q, Tsien RY, Zhang J, Newton AC. Spatio-temporal dynamics of protein kinase B/Akt signaling revealed by a genetically encoded fluorescent reporter. The Journal of Biological Chemistry. 280: 5581-7. PMID 15583002 DOI: 10.1074/Jbc.M411534200 |
0.693 |
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| 2004 |
DiPilato LM, Cheng X, Zhang J. Fluorescent indicators of cAMP and Epac activation reveal differential dynamics of cAMP signaling within discrete subcellular compartments. Proceedings of the National Academy of Sciences of the United States of America. 101: 16513-8. PMID 15545605 DOI: 10.1073/Pnas.0405973101 |
0.842 |
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| 2003 |
Violin JD, Zhang J, Tsien RY, Newton AC. A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C. The Journal of Cell Biology. 161: 899-909. PMID 12782683 DOI: 10.1083/Jcb.200302125 |
0.629 |
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| 2003 |
Zhang J, Campbell RE, Ting AY, Tsien RY. Erratum: Creating New Fluorescent Probes For Cell Biology Nature Reviews Molecular Cell Biology. 4: 80-80. DOI: 10.1038/Nrm1031 |
0.724 |
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| 2002 |
Zhang J, Campbell RE, Ting AY, Tsien RY. Creating new fluorescent probes for cell biology. Nature Reviews. Molecular Cell Biology. 3: 906-18. PMID 12461557 DOI: 10.1038/Nrm976 |
0.767 |
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| 2001 |
Zhang J, Ma Y, Taylor SS, Tsien RY. Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering. Proceedings of the National Academy of Sciences of the United States of America. 98: 14997-5002. PMID 11752448 DOI: 10.1073/Pnas.211566798 |
0.666 |
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| 2000 |
Campbell AM, Tok JB, Zhang J, Wang Y, Stein M, Lynn DG, Binns AN. Xenognosin sensing in virulence: is there a phenol receptor in Agrobacterium tumefaciens? Chemistry & Biology. 7: 65-76. PMID 10662683 DOI: 10.1016/S1074-5521(00)00065-X |
0.364 |
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