| Year |
Citation |
Score |
| 2023 |
Denisov IG, Sligar SG. Solvent isotope effects in the catalytic cycle of P450 CYP17A1: Computational modeling of the hydroxylation and lyase reactions. Journal of Inorganic Biochemistry. 243: 112202. PMID 37004494 DOI: 10.1016/j.jinorgbio.2023.112202 |
0.303 |
|
| 2020 |
McLean MA, Denisov IG, Grinkova YV, Sligar SG. Dark, Ultra-Dark and Ultra-Bright Nanodiscs for membrane protein investigations. Analytical Biochemistry. 113860. PMID 32750355 DOI: 10.1016/J.Ab.2020.113860 |
0.344 |
|
| 2020 |
Liu Y, Denisov I, Grinkova Y, Sligar S, Kincaid JR. P450 CYP17A1 variant with a disordered proton shuttle assembly retains peroxo-mediated lyase efficiency. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 32681807 DOI: 10.1002/Chem.202003181 |
0.381 |
|
| 2020 |
Camp T, Sligar SG. Nanodisc self-assembly is thermodynamically reversible and controllable. Soft Matter. 16: 5615-5623. PMID 32524103 DOI: 10.1039/D0Sm00336K |
0.301 |
|
| 2019 |
Camp T, Mehta K, Sligar SG, Zhang K. Molecular orientation determination in Nanodiscs at the single-molecule level. Analytical Chemistry. PMID 31851490 DOI: 10.1021/Acs.Analchem.9B04950 |
0.324 |
|
| 2019 |
Ivanova L, Denisov IG, Grinkova YV, Sligar SG, Fæste CK. Biotransformation of the Mycotoxin Enniatin B1 by CYP P450 3A4 and Potential for Drug-Drug Interactions. Metabolites. 9. PMID 31357617 DOI: 10.3390/Metabo9080158 |
0.341 |
|
| 2019 |
McLean MA, Stephen AG, Sligar SG. PIP2 Influences the Conformational Dynamics of Membrane bound KRAS4b. Biochemistry. PMID 31339036 DOI: 10.1021/Acs.Biochem.9B00395 |
0.37 |
|
| 2019 |
Denisov IG, Grinkova YV, Nandigrami P, Shekhar M, Tajkhorshid E, Sligar SG. Correction to "Allosteric Interactions in Human Cytochrome P450 CYP3A4: The Role of Phenylalanine 213". Biochemistry. PMID 31181900 DOI: 10.1021/Acs.Biochem.9B00438 |
0.347 |
|
| 2019 |
Camp T, McLean M, Kato M, Cheruzel L, Sligar S. The hydrodynamic motion of Nanodiscs. Chemistry and Physics of Lipids. 220: 28-35. PMID 30802435 DOI: 10.1016/J.Chemphyslip.2019.02.008 |
0.332 |
|
| 2019 |
Denisov IG, Grinkova YV, Nandigrami P, Shekhar M, Tajkhorshid E, Sligar SG. Allosteric Interactions in Human Cytochrome P450 CYP3A4: The Role of Phenylalanine 213. Biochemistry. PMID 30785734 DOI: 10.1021/Acs.Biochem.8B01268 |
0.401 |
|
| 2019 |
Mustafa G, Nandekar PP, Camp TJ, Bruce NJ, Gregory MC, Sligar SG, Wade RC. Influence of Transmembrane Helix Mutations on Cytochrome P450-Membrane Interactions and Function. Biophysical Journal. PMID 30658838 DOI: 10.1016/J.Bpj.2018.12.014 |
0.379 |
|
| 2019 |
McLean MA, Gregory MC, Camp T, Sligar SG. Understanding the Role of Anionic Lipids in the Interaction of KRas4b with the Membrane Surface Biophysical Journal. 116: 298a. DOI: 10.1016/J.Bpj.2018.11.1613 |
0.312 |
|
| 2018 |
Duggal R, Denisov IG, Sligar SG. Cytochrome b enhances androgen synthesis by rapidly reducing the CYP17A1 oxy-complex in the lyase step. Febs Letters. PMID 29888793 DOI: 10.1002/1873-3468.13153 |
0.348 |
|
| 2018 |
Mak PJ, Duggal R, Denisov IG, Gregory MC, Sligar SG, Kincaid JR. Human cytochrome CYP17A1. The structural basis for compromised lyase activity with 17-hydroxyprogesterone. Journal of the American Chemical Society. PMID 29758981 DOI: 10.1021/Jacs.8B03901 |
0.349 |
|
| 2018 |
McLean MA, Gregory MC, Sligar SG. Nanodiscs: A Controlled Bilayer Surface for the Study of Membrane Proteins. Annual Review of Biophysics. PMID 29494254 DOI: 10.1146/Annurev-Biophys-070816-033620 |
0.363 |
|
| 2017 |
Gregory MC, Mak PJ, Khatri Y, Kincaid JR, Sligar SG. Human P450 CYP17A1: Control of Substrate Preference by Asparagine 202. Biochemistry. PMID 29283561 DOI: 10.1021/Acs.Biochem.7B01067 |
0.355 |
|
| 2017 |
Denisov IG, Baylon JL, Grinkova YV, Tajkhorshid E, Sligar SG. Drug-Drug Interactions between Atorvastatin and Dronedarone Mediated by Monomeric CYP3A4. Biochemistry. PMID 29200287 DOI: 10.1021/Acs.Biochem.7B01012 |
0.321 |
|
| 2017 |
Guo Z, Sevrioukova IF, Denisov IG, Zhang X, Chiu TL, Thomas DG, Hanse EA, Cuellar RAD, Grinkova YV, Langenfeld VW, Swedien DS, Stamschror JD, Alvarez J, Luna F, Galván A, ... ... Sligar SG, et al. Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria. Cell Chemical Biology. 24: 1314. PMID 29053951 DOI: 10.1016/J.Chembiol.2017.09.012 |
0.329 |
|
| 2017 |
Wade JH, Jones JD, Lenov IL, Riordan CM, Sligar SG, Bailey RC. Microfluidic platform for efficient Nanodisc assembly, membrane protein incorporation, and purification. Lab On a Chip. PMID 28767110 DOI: 10.1039/C7Lc00601B |
0.367 |
|
| 2017 |
Gregory MC, McLean MA, Sligar SG. Interaction of KRas4b with anionic membranes: A special role for PIP2. Biochemical and Biophysical Research Communications. PMID 28412347 DOI: 10.1016/J.Bbrc.2017.04.063 |
0.382 |
|
| 2017 |
Van Eps N, Caro LN, Morizumi T, Kusnetzow AK, Szczepek M, Hofmann KP, Bayburt TH, Sligar SG, Ernst OP, Hubbell WL. Conformational equilibria of light-activated rhodopsin in nanodiscs. Proceedings of the National Academy of Sciences of the United States of America. PMID 28373559 DOI: 10.1073/Pnas.1620405114 |
0.326 |
|
| 2017 |
Denisov IG, Sligar SG. Nanodiscs in Membrane Biochemistry and Biophysics. Chemical Reviews. PMID 28177242 DOI: 10.1021/Acs.Chemrev.6B00690 |
0.335 |
|
| 2016 |
Her C, Filoti DI, McLean MA, Sligar SG, Alexander Ross JB, Steele H, Laue TM. The Charge Properties of Phospholipid Nanodiscs. Biophysical Journal. 111: 989-98. PMID 27602726 DOI: 10.1016/J.Bpj.2016.06.041 |
0.321 |
|
| 2016 |
Ye X, McLean MA, Sligar SG. PIP2 Modulates the Affinity of Talin-1 for Phospholipid Bilayers and Activates its Auto- Inhibited Form. Biochemistry. PMID 27548281 DOI: 10.1021/Acs.Biochem.6B00497 |
0.322 |
|
| 2016 |
Duggal R, Liu Y, Gregory MC, Denisov IG, Kincaid JR, Sligar SG. Evidence that cytochrome b5 acts as a redox donor in CYP17A1 mediated androgen synthesis. Biochemical and Biophysical Research Communications. PMID 27297105 DOI: 10.1016/J.Bbrc.2016.06.043 |
0.351 |
|
| 2016 |
Denisov IG, Sligar SG. Nanodiscs for structural and functional studies of membrane proteins. Nature Structural & Molecular Biology. 23: 481-6. PMID 27273631 DOI: 10.1038/Nsmb.3195 |
0.365 |
|
| 2016 |
Ye X, McLean MA, Sligar SG. Conformational equilibrium of talin is regulated by anionic lipids. Biochimica Et Biophysica Acta. PMID 27163494 DOI: 10.1016/J.Bbamem.2016.05.005 |
0.326 |
|
| 2015 |
Denisov IG, Mak PJ, Grinkova YV, Bastien D, Bérubé G, Sligar SG, Kincaid JR. The use of isomeric testosterone dimers to explore allosteric effects in substrate binding to cytochrome P450 CYP3A4. Journal of Inorganic Biochemistry. PMID 26774838 DOI: 10.1016/J.Jinorgbio.2015.12.019 |
0.395 |
|
| 2015 |
Mak PJ, Gregory MC, Denisov IG, Sligar SG, Kincaid JR. Unveiling the crucial intermediates in androgen production. Proceedings of the National Academy of Sciences of the United States of America. 112: 15856-61. PMID 26668369 DOI: 10.1073/Pnas.1519376113 |
0.314 |
|
| 2015 |
Skar-Gislinge N, Kynde SA, Denisov IG, Ye X, Lenov I, Sligar SG, Arleth L. Small-angle scattering determination of the shape and localization of human cytochrome P450 embedded in a phospholipid nanodisc environment. Acta Crystallographica. Section D, Biological Crystallography. 71: 2412-21. PMID 26627649 DOI: 10.1107/S1399004715018702 |
0.371 |
|
| 2015 |
Denisov IG, Sligar SG. Metalloproteins: The long and the short of it. Nature Chemistry. 7: 687-8. PMID 26291938 DOI: 10.1038/Nchem.2335 |
0.341 |
|
| 2015 |
Wilcox KC, Marunde MR, Das A, Velasco PT, Kuhns BD, Marty MT, Jiang H, Luan CH, Sligar SG, Klein WL. Nanoscale Synaptic Membrane Mimetic Allows Unbiased High Throughput Screen That Targets Binding Sites for Alzheimer's-Associated Aβ Oligomers. Plos One. 10: e0125263. PMID 25928376 DOI: 10.1371/Journal.Pone.0125263 |
0.528 |
|
| 2015 |
Denisov IG, Grinkova YV, Baylon JL, Tajkhorshid E, Sligar SG. Mechanism of drug-drug interactions mediated by human cytochrome P450 CYP3A4 monomer. Biochemistry. 54: 2227-39. PMID 25777547 DOI: 10.1021/Acs.Biochem.5B00079 |
0.366 |
|
| 2014 |
Khatri Y, Luthra A, Duggal R, Sligar SG. Kinetic solvent isotope effect in steady-state turnover by CYP19A1 suggests involvement of Compound 1 for both hydroxylation and aromatization steps. Febs Letters. 588: 3117-22. PMID 24997347 DOI: 10.1016/J.Febslet.2014.06.050 |
0.3 |
|
| 2014 |
Mak PJ, Luthra A, Sligar SG, Kincaid JR. Resonance Raman spectroscopy of the oxygenated intermediates of human CYP19A1 implicates a compound i intermediate in the final lyase step. Journal of the American Chemical Society. 136: 4825-8. PMID 24645879 DOI: 10.1021/Ja500054C |
0.336 |
|
| 2014 |
Marty MT, Zhang H, Cui W, Gross ML, Sligar SG. Interpretation and deconvolution of nanodisc native mass spectra. Journal of the American Society For Mass Spectrometry. 25: 269-77. PMID 24353133 DOI: 10.1007/S13361-013-0782-Y |
0.304 |
|
| 2014 |
Mak PJ, Gregory MC, Sligar SG, Kincaid JR. Resonance Raman spectroscopy reveals that substrate structure selectively impacts the heme-bound diatomic ligands of CYP17. Biochemistry. 53: 90-100. PMID 24328388 DOI: 10.1021/Bi4014424 |
0.392 |
|
| 2014 |
D'Antona AM, Xie G, Sligar SG, Oprian DD. Assembly of an activated rhodopsin-transducin complex in nanoscale lipid bilayers. Biochemistry. 53: 127-34. PMID 24328127 DOI: 10.1021/Bi4012995 |
0.343 |
|
| 2014 |
Khatri Y, Gregory MC, Grinkova YV, Denisov IG, Sligar SG. Active site proton delivery and the lyase activity of human CYP17A1. Biochemical and Biophysical Research Communications. 443: 179-84. PMID 24299954 DOI: 10.1016/J.Bbrc.2013.11.094 |
0.389 |
|
| 2013 |
Gregory MC, Denisov IG, Grinkova YV, Khatri Y, Sligar SG. Kinetic solvent isotope effect in human P450 CYP17A1-mediated androgen formation: evidence for a reactive peroxoanion intermediate. Journal of the American Chemical Society. 135: 16245-7. PMID 24160919 DOI: 10.1021/Ja4086403 |
0.38 |
|
| 2013 |
Sun Y, Zeng W, Benabbas A, Ye X, Denisov I, Sligar SG, Du J, Dawson JH, Champion PM. Investigations of heme ligation and ligand switching in cytochromes p450 and p420. Biochemistry. 52: 5941-51. PMID 23905516 DOI: 10.1021/Bi400541V |
0.398 |
|
| 2013 |
Vishnivetskiy SA, Ostermaier MK, Singhal A, Panneels V, Homan KT, Glukhova A, Sligar SG, Tesmer JJ, Schertler GF, Standfuss J, Gurevich VV. Constitutively active rhodopsin mutants causing night blindness are effectively phosphorylated by GRKs but differ in arrestin-1 binding. Cellular Signalling. 25: 2155-62. PMID 23872075 DOI: 10.1016/J.Cellsig.2013.07.009 |
0.319 |
|
| 2013 |
Baylon JL, Lenov IL, Sligar SG, Tajkhorshid E. Characterizing the membrane-bound state of cytochrome P450 3A4: structure, depth of insertion, and orientation. Journal of the American Chemical Society. 135: 8542-51. PMID 23697766 DOI: 10.1021/Ja4003525 |
0.404 |
|
| 2013 |
Gregory M, Mak PJ, Sligar SG, Kincaid JR. Differential hydrogen bonding in human CYP17 dictates hydroxylation versus lyase chemistry. Angewandte Chemie (International Ed. in English). 52: 5342-5. PMID 23576395 DOI: 10.1002/Anie.201300760 |
0.319 |
|
| 2013 |
Luthra A, Gregory M, Grinkova YV, Denisov IG, Sligar SG. Nanodiscs in the studies of membrane-bound cytochrome P450 enzymes. Methods in Molecular Biology (Clifton, N.J.). 987: 115-27. PMID 23475672 DOI: 10.1007/978-1-62703-321-3_10 |
0.471 |
|
| 2013 |
Sloan CD, Marty MT, Sligar SG, Bailey RC. Interfacing lipid bilayer nanodiscs and silicon photonic sensor arrays for multiplexed protein-lipid and protein-membrane protein interaction screening. Analytical Chemistry. 85: 2970-6. PMID 23425255 DOI: 10.1021/Ac3037359 |
0.36 |
|
| 2013 |
Schuler MA, Denisov IG, Sligar SG. Nanodiscs as a new tool to examine lipid-protein interactions. Methods in Molecular Biology (Clifton, N.J.). 974: 415-33. PMID 23404286 DOI: 10.1007/978-1-62703-275-9_18 |
0.376 |
|
| 2013 |
Marty MT, Wilcox KC, Klein WL, Sligar SG. Nanodisc-solubilized membrane protein library reflects the membrane proteome. Analytical and Bioanalytical Chemistry. 405: 4009-16. PMID 23400332 DOI: 10.1007/S00216-013-6790-8 |
0.347 |
|
| 2013 |
Grinkova YV, Denisov IG, McLean MA, Sligar SG. Oxidase uncoupling in heme monooxygenases: human cytochrome P450 CYP3A4 in Nanodiscs. Biochemical and Biophysical Research Communications. 430: 1223-7. PMID 23266608 DOI: 10.1016/J.Bbrc.2012.12.072 |
0.403 |
|
| 2012 |
Marty MT, Zhang H, Cui W, Blankenship RE, Gross ML, Sligar SG. Native mass spectrometry characterization of intact nanodisc lipoprotein complexes. Analytical Chemistry. 84: 8957-60. PMID 23061736 DOI: 10.1021/Ac302663F |
0.347 |
|
| 2012 |
Denisov IG, Grinkova YV, Sligar SG. Cryoradiolysis and cryospectroscopy for studies of heme-oxygen intermediates in cytochromes p450. Methods in Molecular Biology (Clifton, N.J.). 875: 375-91. PMID 22573452 DOI: 10.1007/978-1-61779-806-1_20 |
0.367 |
|
| 2012 |
Morrissey JH, Tajkhorshid E, Sligar SG, Rienstra CM. Tissue factor/factor VIIa complex: role of the membrane surface. Thrombosis Research. 129: S8-10. PMID 22417943 DOI: 10.1016/J.Thromres.2012.02.019 |
0.363 |
|
| 2012 |
Dalal K, Chan CS, Sligar SG, Duong F. Two copies of the SecY channel and acidic lipids are necessary to activate the SecA translocation ATPase. Proceedings of the National Academy of Sciences of the United States of America. 109: 4104-9. PMID 22378651 DOI: 10.1073/Pnas.1117783109 |
0.335 |
|
| 2012 |
Denisov IG, Sligar SG. A novel type of allosteric regulation: functional cooperativity in monomeric proteins. Archives of Biochemistry and Biophysics. 519: 91-102. PMID 22245335 DOI: 10.1016/J.Abb.2011.12.017 |
0.439 |
|
| 2012 |
Denisov IG, Shih AY, Sligar SG. Structural differences between soluble and membrane bound cytochrome P450s. Journal of Inorganic Biochemistry. 108: 150-8. PMID 22244217 DOI: 10.1016/J.Jinorgbio.2011.11.026 |
0.668 |
|
| 2012 |
Näsvik Öjemyr L, von Ballmoos C, Gennis RB, Sligar SG, Brzezinski P. Reconstitution of respiratory oxidases in membrane nanodiscs for investigation of proton-coupled electron transfer. Febs Letters. 586: 640-5. PMID 22209982 DOI: 10.1016/J.Febslet.2011.12.023 |
0.374 |
|
| 2012 |
Marty MT, Das A, Sligar SG. Ultra-thin layer MALDI mass spectrometry of membrane proteins in nanodiscs. Analytical and Bioanalytical Chemistry. 402: 721-9. PMID 22057720 DOI: 10.1007/S00216-011-5512-3 |
0.518 |
|
| 2012 |
Sligar SG. Self-Assembled Nanometer Scale Lipid Bilayers for Elucidating the Structure and Function of Membrane Proteins Biophysical Journal. 102: 439a. DOI: 10.1016/J.Bpj.2011.11.2404 |
0.36 |
|
| 2011 |
Luthra A, Denisov IG, Sligar SG. Temperature derivative spectroscopy to monitor the autoxidation decay of cytochromes P450. Analytical Chemistry. 83: 5394-9. PMID 21615185 DOI: 10.1021/Ac2009349 |
0.415 |
|
| 2011 |
Karunakaran V, Denisov I, Sligar SG, Champion PM. Investigation of the low frequency dynamics of heme proteins: native and mutant cytochrome P450(cam) and redox partner complexes. The Journal of Physical Chemistry. B. 115: 5665-77. PMID 21391540 DOI: 10.1016/J.Bpj.2009.12.3512 |
0.363 |
|
| 2011 |
Mak PJ, Denisov IG, Grinkova YV, Sligar SG, Kincaid JR. Defining CYP3A4 structural responses to substrate binding. Raman spectroscopic studies of a nanodisc-incorporated mammalian cytochrome P450. Journal of the American Chemical Society. 133: 1357-66. PMID 21207936 DOI: 10.1021/Ja105869P |
0.399 |
|
| 2011 |
Frank DJ, Denisov IG, Sligar SG. Analysis of heterotropic cooperativity in cytochrome P450 3A4 using alpha-naphthoflavone and testosterone. The Journal of Biological Chemistry. 286: 5540-5. PMID 21177853 DOI: 10.1074/Jbc.M110.182055 |
0.639 |
|
| 2011 |
Luthra A, Denisov IG, Sligar SG. Spectroscopic features of cytochrome P450 reaction intermediates. Archives of Biochemistry and Biophysics. 507: 26-35. PMID 21167809 DOI: 10.1016/J.Abb.2010.12.008 |
0.43 |
|
| 2011 |
Bayburt TH, Vishnivetskiy SA, McLean MA, Morizumi T, Huang CC, Tesmer JJ, Ernst OP, Sligar SG, Gurevich VV. Monomeric rhodopsin is sufficient for normal rhodopsin kinase (GRK1) phosphorylation and arrestin-1 binding. The Journal of Biological Chemistry. 286: 1420-8. PMID 20966068 DOI: 10.1074/Jbc.M110.151043 |
0.381 |
|
| 2011 |
Denisov IG, Sligar SG. Cytochromes P450 in nanodiscs. Biochimica Et Biophysica Acta. 1814: 223-9. PMID 20685623 DOI: 10.1016/J.Bbapap.2010.05.017 |
0.46 |
|
| 2010 |
Sligar SG. Chemistry. Glimpsing the critical intermediate in cytochrome P450 oxidations. Science (New York, N.Y.). 330: 924-5. PMID 21071657 DOI: 10.1126/Science.1197881 |
0.366 |
|
| 2010 |
Ham MH, Choi JH, Boghossian AA, Jeng ES, Graff RA, Heller DA, Chang AC, Mattis A, Bayburt TH, Grinkova YV, Zeiger AS, Van Vliet KJ, Hobbie EK, Sligar SG, Wraight CA, et al. Photoelectrochemical complexes for solar energy conversion that chemically and autonomously regenerate. Nature Chemistry. 2: 929-36. PMID 20966948 DOI: 10.1038/Nchem.822 |
0.301 |
|
| 2010 |
Tark SH, Das A, Sligar S, Dravid VP. Nanomechanical detection of cholera toxin using microcantilevers functionalized with ganglioside nanodiscs. Nanotechnology. 21: 435502. PMID 20890017 DOI: 10.1088/0957-4484/21/43/435502 |
0.511 |
|
| 2010 |
Skar-Gislinge N, Simonsen JB, Mortensen K, Feidenhans'l R, Sligar SG, Lindberg Møller B, Bjørnholm T, Arleth L. Elliptical structure of phospholipid bilayer nanodiscs encapsulated by scaffold proteins: casting the roles of the lipids and the protein. Journal of the American Chemical Society. 132: 13713-22. PMID 20828154 DOI: 10.1021/Ja1030613 |
0.365 |
|
| 2010 |
Grinkova YV, Denisov IG, Sligar SG. Engineering extended membrane scaffold proteins for self-assembly of soluble nanoscale lipid bilayers. Protein Engineering, Design & Selection : Peds. 23: 843-8. PMID 20817758 DOI: 10.1093/Protein/Gzq060 |
0.363 |
|
| 2010 |
Kijac A, Shih AY, Nieuwkoop AJ, Schulten K, Sligar SG, Rienstra CM. Lipid-protein correlations in nanoscale phospholipid bilayers determined by solid-state nuclear magnetic resonance. Biochemistry. 49: 9190-8. PMID 20804175 DOI: 10.1021/Bi1013722 |
0.79 |
|
| 2010 |
Früh V, Zhou Y, Chen D, Loch C, Ab E, Grinkova YN, Verheij H, Sligar SG, Bushweller JH, Siegal G. Application of fragment-based drug discovery to membrane proteins: identification of ligands of the integral membrane enzyme DsbB. Chemistry & Biology. 17: 881-91. PMID 20797617 DOI: 10.1016/J.Chembiol.2010.06.011 |
0.355 |
|
| 2010 |
Grinkova YV, Denisov IG, Sligar SG. Functional reconstitution of monomeric CYP3A4 with multiple cytochrome P450 reductase molecules in Nanodiscs. Biochemical and Biophysical Research Communications. 398: 194-8. PMID 20599740 DOI: 10.1016/J.Bbrc.2010.06.058 |
0.447 |
|
| 2010 |
Ye F, Hu G, Taylor D, Ratnikov B, Bobkov AA, McLean MA, Sligar SG, Taylor KA, Ginsberg MH. Recreation of the terminal events in physiological integrin activation. The Journal of Cell Biology. 188: 157-73. PMID 20048261 DOI: 10.1083/Jcb.200908045 |
0.31 |
|
| 2010 |
Davydov DR, Sineva EV, Sistla S, Davydova NY, Frank DJ, Sligar SG, Halpert JR. Electron transfer in the complex of membrane-bound human cytochrome P450 3A4 with the flavin domain of P450BM-3: the effect of oligomerization of the heme protein and intermittent modulation of the spin equilibrium. Biochimica Et Biophysica Acta. 1797: 378-90. PMID 20026040 DOI: 10.1016/J.Bbabio.2009.12.008 |
0.676 |
|
| 2010 |
Bayburt TH, Sligar SG. Membrane protein assembly into Nanodiscs. Febs Letters. 584: 1721-7. PMID 19836392 DOI: 10.1016/J.Febslet.2009.10.024 |
0.36 |
|
| 2010 |
Jollie DR, Sligar SG, Schuler M. Purification and Characterization of Microsomal Cytochrome b(5) and NADH Cytochrome b(5) Reductase from Pisum sativum. Plant Physiology. 85: 457-62. PMID 16665720 DOI: 10.1104/Pp.85.2.457 |
0.311 |
|
| 2009 |
Das A, Sligar SG. Modulation of the cytochrome P450 reductase redox potential by the phospholipid bilayer. Biochemistry. 48: 12104-12. PMID 19908820 DOI: 10.1021/Bi9011435 |
0.577 |
|
| 2009 |
Ritchie TK, Grinkova YV, Bayburt TH, Denisov IG, Zolnerciks JK, Atkins WM, Sligar SG. Chapter 11 - Reconstitution of membrane proteins in phospholipid bilayer nanodiscs. Methods in Enzymology. 464: 211-31. PMID 19903557 DOI: 10.1016/S0076-6879(09)64011-8 |
0.372 |
|
| 2009 |
Morrissey JH, Pureza V, Davis-Harrison RL, Sligar SG, Rienstra CM, Kijac AZ, Ohkubo YZ, Tajkhorshid E. Protein-membrane interactions: blood clotting on nanoscale bilayers. Journal of Thrombosis and Haemostasis : Jth. 7: 169-72. PMID 19630793 DOI: 10.1111/J.1538-7836.2009.03390.X |
0.795 |
|
| 2009 |
Gantt SL, Denisov IG, Grinkova YV, Sligar SG. The critical iron-oxygen intermediate in human aromatase. Biochemical and Biophysical Research Communications. 387: 169-73. PMID 19591804 DOI: 10.1016/J.Bbrc.2009.06.154 |
0.366 |
|
| 2009 |
Shih AY, Sligar SG, Schulten K. Maturation of high-density lipoproteins. Journal of the Royal Society, Interface / the Royal Society. 6: 863-71. PMID 19570799 DOI: 10.1098/Rsif.2009.0173 |
0.56 |
|
| 2009 |
Frank DJ, Denisov IG, Sligar SG. Mixing apples and oranges: Analysis of heterotropic cooperativity in cytochrome P450 3A4. Archives of Biochemistry and Biophysics. 488: 146-52. PMID 19560436 DOI: 10.1016/J.Abb.2009.06.013 |
0.646 |
|
| 2009 |
Denisov IG, Frank DJ, Sligar SG. Cooperative properties of cytochromes P450. Pharmacology & Therapeutics. 124: 151-67. PMID 19555717 DOI: 10.1016/J.Pharmthera.2009.05.011 |
0.648 |
|
| 2009 |
Das A, Zhao J, Schatz GC, Sligar SG, Van Duyne RP. Screening of type I and II drug binding to human cytochrome P450-3A4 in nanodiscs by localized surface plasmon resonance spectroscopy. Analytical Chemistry. 81: 3754-9. PMID 19364136 DOI: 10.1021/Ac802612Z |
0.528 |
|
| 2009 |
McLean MA, Rajfur Z, Chen Z, Humphrey D, Yang B, Sligar SG, Jacobson K. Mechanism of chromophore assisted laser inactivation employing fluorescent proteins. Analytical Chemistry. 81: 1755-61. PMID 19199572 DOI: 10.1021/Ac801663Y |
0.319 |
|
| 2008 |
Li H, Das A, Sibhatu H, Jamal J, Sligar SG, Poulos TL. Exploring the electron transfer properties of neuronal nitric-oxide synthase by reversal of the FMN redox potential. The Journal of Biological Chemistry. 283: 34762-72. PMID 18852262 DOI: 10.1074/Jbc.M806949200 |
0.522 |
|
| 2008 |
Goluch ED, Shaw AW, Sligar SG, Liu C. Microfluidic patterning of nanodisc lipid bilayers and multiplexed analysis of protein interaction. Lab On a Chip. 8: 1723-8. PMID 18813396 DOI: 10.1039/B806733C |
0.558 |
|
| 2008 |
Morrissey JH, Pureza V, Davis-Harrison RL, Sligar SG, Ohkubo YZ, Tajkhorshid E. Blood clotting reactions on nanoscale phospholipid bilayers. Thrombosis Research. 122: S23-6. PMID 18691494 DOI: 10.1016/S0049-3848(08)70014-8 |
0.349 |
|
| 2008 |
Denisov IG, Mak PJ, Makris TM, Sligar SG, Kincaid JR. Resonance Raman characterization of the peroxo and hydroperoxo intermediates in cytochrome P450. The Journal of Physical Chemistry. A. 112: 13172-9. PMID 18630867 DOI: 10.1021/Jp8017875 |
0.612 |
|
| 2008 |
Borch J, Torta F, Sligar SG, Roepstorff P. Nanodiscs for immobilization of lipid bilayers and membrane receptors: kinetic analysis of cholera toxin binding to a glycolipid receptor. Analytical Chemistry. 80: 6245-52. PMID 18616345 DOI: 10.1021/Ac8000644 |
0.338 |
|
| 2008 |
Kühnel K, Ke N, Cryle MJ, Sligar SG, Schuler MA, Schlichting I. Crystal structures of substrate-free and retinoic acid-bound cyanobacterial cytochrome P450 CYP120A1. Biochemistry. 47: 6552-9. PMID 18512957 DOI: 10.1021/Bi800328S |
0.628 |
|
| 2008 |
Grinkova YV, Denisov IG, Waterman MR, Arase M, Kagawa N, Sligar SG. The ferrous-oxy complex of human aromatase. Biochemical and Biophysical Research Communications. 372: 379-82. PMID 18482580 DOI: 10.1016/J.Bbrc.2008.05.011 |
0.369 |
|
| 2008 |
Gruia F, Ionascu D, Kubo M, Ye X, Dawson J, Osborne RL, Sligar SG, Denisov I, Das A, Poulos TL, Terner J, Champion PM. Low-frequency dynamics of Caldariomyces fumago chloroperoxidase probed by femtosecond coherence spectroscopy. Biochemistry. 47: 5156-67. PMID 18407660 DOI: 10.1021/Bi7025485 |
0.484 |
|
| 2008 |
Shih AY, Sligar SG, Schulten K. Molecular models need to be tested: the case of a solar flares discoidal HDL model. Biophysical Journal. 94: L87-9. PMID 18375520 DOI: 10.1529/Biophysj.108.131581 |
0.569 |
|
| 2008 |
Newcomb M, Halgrimson JA, Horner JH, Wasinger EC, Chen LX, Sligar SG. X-ray absorption spectroscopic characterization of a cytochrome P450 compound II derivative. Proceedings of the National Academy of Sciences of the United States of America. 105: 8179-84. PMID 18174331 DOI: 10.1073/Pnas.0708299105 |
0.321 |
|
| 2008 |
Zhao J, Das A, Schatz GC, Sligar SG, Van Duyne RP. Resonance localized surface plasmon spectroscopy: Sensing substrate and inhibitor binding to cytochrome P450 Journal of Physical Chemistry C. 112: 13084-13088. DOI: 10.1021/Jp801719C |
0.543 |
|
| 2008 |
Gruia F, Ionascu D, Kubo M, Ye X, Dawson J, Osborne RL, Sligar SG, Denisov I, Das A, Poulos TL, Terner J, Champion PM. Low-frequency dynamics of Caldariomyces fumago chloroperoxidase probed by femtosecond coherence spectroscopy (Biochemistry (2008) 47, 18, (5156-5167)) Biochemistry. 47: 9344. DOI: 10.1021/Bi801317Z |
0.431 |
|
| 2008 |
Shih AY, Freddolino PL, Arkhipov A, Sligar SG, Schulten K. Chapter 11 Molecular Modeling of the Structural Properties and Formation of High-Density Lipoprotein Particles Current Topics in Membranes. 60: 313-342. DOI: 10.1016/S1063-5823(08)00011-2 |
0.554 |
|
| 2007 |
Makris TM, von Koenig K, Schlichting I, Sligar SG. Alteration of P450 distal pocket solvent leads to impaired proton delivery and changes in heme geometry. Biochemistry. 46: 14129-40. PMID 18001135 DOI: 10.1021/Bi7013695 |
0.668 |
|
| 2007 |
Kijac AZ, Li Y, Sligar SG, Rienstra CM. Magic-angle spinning solid-state NMR spectroscopy of nanodisc-embedded human CYP3A4. Biochemistry. 46: 13696-703. PMID 17985934 DOI: 10.1021/Bi701411G |
0.816 |
|
| 2007 |
Das A, Grinkova YV, Sligar SG. Redox potential control by drug binding to cytochrome P450 3A4. Journal of the American Chemical Society. 129: 13778-9. PMID 17948999 DOI: 10.1021/Ja074864X |
0.612 |
|
| 2007 |
Marin VL, Bayburt TH, Sligar SG, Mrksich M. Functional assays of membrane-bound proteins with SAMDI-TOF mass spectrometry. Angewandte Chemie (International Ed. in English). 46: 8796-8. PMID 17943935 DOI: 10.1002/Anie.200702694 |
0.39 |
|
| 2007 |
Denisov IG, Dawson JH, Hager LP, Sligar SG. The ferric-hydroperoxo complex of chloroperoxidase. Biochemical and Biophysical Research Communications. 363: 954-8. PMID 17920039 DOI: 10.1016/J.Bbrc.2007.09.085 |
0.373 |
|
| 2007 |
Sligar SG, Denisov IG. Understanding cooperativity in human p450 mediated drug-drug interactions. Drug Metabolism Reviews. 39: 567-79. PMID 17786639 DOI: 10.1080/03602530701498521 |
0.319 |
|
| 2007 |
Shih AY, Arkhipov A, Freddolino PL, Sligar SG, Schulten K. Assembly of lipids and proteins into lipoprotein particles. The Journal of Physical Chemistry. B. 111: 11095-104. PMID 17696388 DOI: 10.1021/Jp072320B |
0.573 |
|
| 2007 |
Denisov IG, Grinkova YV, McLean MA, Sligar SG. The one-electron autoxidation of human cytochrome P450 3A4. The Journal of Biological Chemistry. 282: 26865-73. PMID 17650504 DOI: 10.1074/Jbc.M704747200 |
0.416 |
|
| 2007 |
Kimmich N, Das A, Sevrioukova I, Meharenna Y, Sligar SG, Poulos TL. Electron transfer between cytochrome P450cin and its FMN-containing redox partner, cindoxin. The Journal of Biological Chemistry. 282: 27006-11. PMID 17606612 DOI: 10.1074/Jbc.M703790200 |
0.521 |
|
| 2007 |
Nath A, Grinkova YV, Sligar SG, Atkins WM. Ligand binding to cytochrome P450 3A4 in phospholipid bilayer nanodiscs: the effect of model membranes. The Journal of Biological Chemistry. 282: 28309-20. PMID 17573349 DOI: 10.1074/Jbc.M703568200 |
0.4 |
|
| 2007 |
Davydov DR, Baas BJ, Sligar SG, Halpert JR. Allosteric mechanisms in cytochrome P450 3A4 studied by high-pressure spectroscopy: pivotal role of substrate-induced changes in the accessibility and degree of hydration of the heme pocket. Biochemistry. 46: 7852-64. PMID 17555301 DOI: 10.1021/Bi602400Y |
0.768 |
|
| 2007 |
Shih AY, Freddolino PL, Sligar SG, Schulten K. Disassembly of nanodiscs with cholate. Nano Letters. 7: 1692-6. PMID 17503871 DOI: 10.1021/Nl0706906 |
0.593 |
|
| 2007 |
Mak PJ, Denisov IG, Victoria D, Makris TM, Deng T, Sligar SG, Kincaid JR. Resonance Raman detection of the hydroperoxo intermediate in the cytochrome P450 enzymatic cycle. Journal of the American Chemical Society. 129: 6382-3. PMID 17461587 DOI: 10.1021/Ja071426H |
0.619 |
|
| 2007 |
Alami M, Dalal K, Lelj-Garolla B, Sligar SG, Duong F. Nanodiscs unravel the interaction between the SecYEG channel and its cytosolic partner SecA. The Embo Journal. 26: 1995-2004. PMID 17396152 DOI: 10.1038/Sj.Emboj.7601661 |
0.391 |
|
| 2007 |
Bayburt TH, Leitz AJ, Xie G, Oprian DD, Sligar SG. Transducin activation by nanoscale lipid bilayers containing one and two rhodopsins. The Journal of Biological Chemistry. 282: 14875-81. PMID 17395586 DOI: 10.1074/Jbc.M701433200 |
0.338 |
|
| 2007 |
Nath A, Atkins WM, Sligar SG. Applications of phospholipid bilayer nanodiscs in the study of membranes and membrane proteins. Biochemistry. 46: 2059-69. PMID 17263563 DOI: 10.1021/Bi602371N |
0.358 |
|
| 2007 |
Denisov IG, Baas BJ, Grinkova YV, Sligar SG. Cooperativity in cytochrome P450 3A4: linkages in substrate binding, spin state, uncoupling, and product formation. The Journal of Biological Chemistry. 282: 7066-76. PMID 17213193 DOI: 10.1074/Jbc.M609589200 |
0.794 |
|
| 2007 |
Shaw AW, Pureza VS, Sligar SG, Morrissey JH. The local phospholipid environment modulates the activation of blood clotting. The Journal of Biological Chemistry. 282: 6556-63. PMID 17200119 DOI: 10.1074/Jbc.M607973200 |
0.574 |
|
| 2007 |
Schuler MA, Sligar SG. Diversities and similarities in P450 systems: An introduction Metal Ions in Life Sciences. 3: 1-26. DOI: 10.1002/9780470028155.Ch1 |
0.32 |
|
| 2006 |
Zhao J, Das A, Zhang X, Schatz GC, Sligar SG, Van Duyne RP. Resonance surface plasmon spectroscopy: low molecular weight substrate binding to cytochrome p450. Journal of the American Chemical Society. 128: 11004-5. PMID 16925400 DOI: 10.1021/Ja0636082 |
0.55 |
|
| 2006 |
Li Y, Kijac AZ, Sligar SG, Rienstra CM. Structural analysis of nanoscale self-assembled discoidal lipid bilayers by solid-state NMR spectroscopy. Biophysical Journal. 91: 3819-28. PMID 16905610 DOI: 10.1529/Biophysj.106.087072 |
0.796 |
|
| 2006 |
Boldog T, Grimme S, Li M, Sligar SG, Hazelbauer GL. Nanodiscs separate chemoreceptor oligomeric states and reveal their signaling properties. Proceedings of the National Academy of Sciences of the United States of America. 103: 11509-14. PMID 16864771 DOI: 10.1073/Pnas.0604988103 |
0.309 |
|
| 2006 |
Denisov IG, Grinkova YV, Baas BJ, Sligar SG. The ferrous-dioxygen intermediate in human cytochrome P450 3A4. Substrate dependence of formation and decay kinetics. The Journal of Biological Chemistry. 281: 23313-8. PMID 16762915 DOI: 10.1074/Jbc.M605511200 |
0.787 |
|
| 2006 |
Leitz AJ, Bayburt TH, Barnakov AN, Springer BA, Sligar SG. Functional reconstitution of Beta2-adrenergic receptors utilizing self-assembling Nanodisc technology. Biotechniques. 40: 601-2, 604, 606, pas. PMID 16708760 DOI: 10.2144/000112169 |
0.319 |
|
| 2006 |
Bayburt TH, Grinkova YV, Sligar SG. Assembly of single bacteriorhodopsin trimers in bilayer nanodiscs. Archives of Biochemistry and Biophysics. 450: 215-22. PMID 16620766 DOI: 10.1016/J.Abb.2006.03.013 |
0.333 |
|
| 2006 |
Newcomb M, Zhang R, Chandrasena RE, Halgrimson JA, Horner JH, Makris TM, Sligar SG. Cytochrome p450 compound I. Journal of the American Chemical Society. 128: 4580-1. PMID 16594688 DOI: 10.1021/Ja060048Y |
0.647 |
|
| 2006 |
Makris TM, von Koenig K, Schlichting I, Sligar SG. The status of high-valent metal oxo complexes in the P450 cytochromes. Journal of Inorganic Biochemistry. 100: 507-18. PMID 16510191 DOI: 10.1016/J.Jinorgbio.2006.01.025 |
0.673 |
|
| 2005 |
Denisov IG, McLean MA, Shaw AW, Grinkova YV, Sligar SG. Thermotropic phase transition in soluble nanoscale lipid bilayers. The Journal of Physical Chemistry. B. 109: 15580-8. PMID 16852976 DOI: 10.1021/Jp051385G |
0.576 |
|
| 2005 |
Davydov DR, Fernando H, Baas BJ, Sligar SG, Halpert JR. Kinetics of dithionite-dependent reduction of cytochrome P450 3A4: heterogeneity of the enzyme caused by its oligomerization. Biochemistry. 44: 13902-13. PMID 16229479 DOI: 10.1021/Bi0509346 |
0.787 |
|
| 2005 |
Sligar SG, Makris TM, Denisov IG. Thirty years of microbial P450 monooxygenase research: peroxo-heme intermediates--the central bus station in heme oxygenase catalysis. Biochemical and Biophysical Research Communications. 338: 346-54. PMID 16139790 DOI: 10.1016/J.Bbrc.2005.08.094 |
0.632 |
|
| 2005 |
Denisov IG, Makris TM, Sligar SG, Schlichting I. Structure and chemistry of cytochrome P450. Chemical Reviews. 105: 2253-77. PMID 15941214 DOI: 10.1021/Cr0307143 |
0.669 |
|
| 2005 |
Ke N, Baudry J, Makris TM, Schuler MA, Sligar SG. A retinoic acid binding cytochrome P450: CYP120A1 from Synechocystis sp. PCC 6803. Archives of Biochemistry and Biophysics. 436: 110-20. PMID 15752715 DOI: 10.1016/J.Abb.2005.01.011 |
0.764 |
|
| 2005 |
Sono M, Perera R, Jin S, Makris TM, Sligar SG, Bryson TA, Dawson JH. The influence of substrate on the spectral properties of oxyferrous wild-type and T252A cytochrome P450-CAM. Archives of Biochemistry and Biophysics. 436: 40-9. PMID 15752707 DOI: 10.1016/J.Abb.2004.12.026 |
0.676 |
|
| 2005 |
Shih AY, Denisov IG, Phillips JC, Sligar SG, Schulten K. Molecular dynamics simulations of discoidal bilayers assembled from truncated human lipoproteins. Biophysical Journal. 88: 548-56. PMID 15533924 DOI: 10.1529/Biophysj.104.046896 |
0.62 |
|
| 2005 |
Makris TM, Denisov I, Schlichting I, Sligar SG. Activation of molecular oxygen by cytochrome P450 Cytochrome P450: Structure, Mechanism, and Biochemistry: Third Edition. 149-182. DOI: 10.1007/0-387-27447-2_5 |
0.608 |
|
| 2004 |
Baas BJ, Denisov IG, Sligar SG. Homotropic cooperativity of monomeric cytochrome P450 3A4 in a nanoscale native bilayer environment. Archives of Biochemistry and Biophysics. 430: 218-28. PMID 15369821 DOI: 10.1016/J.Abb.2004.07.003 |
0.782 |
|
| 2004 |
Duan H, Civjan NR, Sligar SG, Schuler MA. Co-incorporation of heterologously expressed Arabidopsis cytochrome P450 and P450 reductase into soluble nanoscale lipid bilayers. Archives of Biochemistry and Biophysics. 424: 141-53. PMID 15047186 DOI: 10.1016/J.Abb.2004.02.010 |
0.806 |
|
| 2004 |
Denisov IG, Grinkova YV, Lazarides AA, Sligar SG. Directed self-assembly of monodisperse phospholipid bilayer Nanodiscs with controlled size. Journal of the American Chemical Society. 126: 3477-87. PMID 15025475 DOI: 10.1021/Ja0393574 |
0.327 |
|
| 2004 |
Shaw AW, McLean MA, Sligar SG. Phospholipid phase transitions in homogeneous nanometer scale bilayer discs. Febs Letters. 556: 260-4. PMID 14706860 DOI: 10.1016/S0014-5793(03)01400-5 |
0.562 |
|
| 2004 |
Schünemann V, Lendzian F, Jung C, Contzen J, Barra AL, Sligar SG, Trautwein AX. Tyrosine radical formation in the reaction of wild type and mutant cytochrome P450cam with peroxy acids: a multifrequency EPR study of intermediates on the millisecond time scale. The Journal of Biological Chemistry. 279: 10919-30. PMID 14688245 DOI: 10.1074/Jbc.M307884200 |
0.314 |
|
| 2003 |
Sligar SG. Finding a single-molecule solution for membrane proteins. Biochemical and Biophysical Research Communications. 312: 115-9. PMID 14630028 DOI: 10.1016/J.Bbrc.2003.09.188 |
0.31 |
|
| 2003 |
Ibrahim M, Denisov IG, Makris TM, Kincaid JR, Sligar SG. Resonance Raman spectroscopic studies of hydroperoxo-myoglobin at cryogenic temperatures. Journal of the American Chemical Society. 125: 13714-8. PMID 14599210 DOI: 10.1021/Ja036949D |
0.601 |
|
| 2003 |
Bayburt TH, Sligar SG. Self-assembly of single integral membrane proteins into soluble nanoscale phospholipid bilayers. Protein Science : a Publication of the Protein Society. 12: 2476-81. PMID 14573860 DOI: 10.1110/Ps.03267503 |
0.374 |
|
| 2003 |
Civjan NR, Bayburt TH, Schuler MA, Sligar SG. Direct solubilization of heterologously expressed membrane proteins by incorporation into nanoscale lipid bilayers. Biotechniques. 35: 556-60, 562-3. PMID 14513561 DOI: 10.2144/03353Rr02 |
0.786 |
|
| 2003 |
Makris TM, Denisov IG, Sligar SG. Haem-oxygen reactive intermediates: catalysis by the two-step. Biochemical Society Transactions. 31: 516-9. PMID 12773147 DOI: 10.1042/Bst0310516 |
0.653 |
|
| 2003 |
Jin S, Makris TM, Bryson TA, Sligar SG, Dawson JH. Epoxidation of olefins by hydroperoxo-ferric cytochrome P450. Journal of the American Chemical Society. 125: 3406-7. PMID 12643683 DOI: 10.1021/Ja029272N |
0.661 |
|
| 2002 |
Makris TM, Davydov R, Denisov IG, Hoffman BM, Sligar SG. Mechanistic enzymology of oxygen activation by the cytochromes P450. Drug Metabolism Reviews. 34: 691-708. PMID 12487147 DOI: 10.1081/Dmr-120015691 |
0.687 |
|
| 2002 |
Denisov IG, Ikeda-Saito M, Yoshida T, Sligar SG. Cryogenic absorption spectra of hydroperoxo-ferric heme oxygenase, the active intermediate of enzymatic heme oxygenation. Febs Letters. 532: 203-6. PMID 12459490 DOI: 10.1016/S0014-5793(02)03674-8 |
0.342 |
|
| 2002 |
Dmochowski IJ, Dunn AR, Wilker JJ, Crane BR, Green MT, Dawson JH, Sligar SG, Winkler JR, Gray HB. Sensitizer-linked substrates and ligands: ruthenium probes of cytochrome P450 structure and mechanism. Methods in Enzymology. 357: 120-33. PMID 12424904 DOI: 10.1016/S0076-6879(02)57672-2 |
0.308 |
|
| 2002 |
Denisov IG, Makris TM, Sligar SG. Cryoradiolysis for the study of P450 reaction intermediates. Methods in Enzymology. 357: 103-15. PMID 12424902 DOI: 10.1016/S0076-6879(02)57670-9 |
0.637 |
|
| 2002 |
Park SY, Yamane K, Adachi S, Shiro Y, Weiss KE, Maves SA, Sligar SG. Thermophilic cytochrome P450 (CYP119) from Sulfolobus solfataricus: high resolution structure and functional properties. Journal of Inorganic Biochemistry. 91: 491-501. PMID 12237217 DOI: 10.1016/S0162-0134(02)00446-4 |
0.796 |
|
| 2002 |
Denisov IG, Makris TM, Sligar SG. Formation and decay of hydroperoxo-ferric heme complex in horseradish peroxidase studied by cryoradiolysis. The Journal of Biological Chemistry. 277: 42706-10. PMID 12215454 DOI: 10.1074/Jbc.M207949200 |
0.632 |
|
| 2002 |
Bayburt TH, Sligar SG. Single-molecule height measurements on microsomal cytochrome P450 in nanometer-scale phospholipid bilayer disks. Proceedings of the National Academy of Sciences of the United States of America. 99: 6725-30. PMID 11997441 DOI: 10.1073/Pnas.062565599 |
0.407 |
|
| 2002 |
Hui Bon Hoa G, McLean MA, Sligar SG. High pressure, a tool for exploring heme protein active sites. Biochimica Et Biophysica Acta. 1595: 297-308. PMID 11983404 DOI: 10.1016/S0167-4838(01)00352-1 |
0.436 |
|
| 2002 |
Lynch TW, Sligar SG. Experimental and theoretical high pressure strategies for investigating protein-nucleic acid assemblies. Biochimica Et Biophysica Acta. 1595: 277-82. PMID 11983402 DOI: 10.1016/S0167-4838(01)00350-8 |
0.612 |
|
| 2002 |
Kellner DG, Hung SC, Weiss KE, Sligar SG. Kinetic characterization of compound I formation in the thermostable cytochrome P450 CYP119. The Journal of Biological Chemistry. 277: 9641-4. PMID 11799104 DOI: 10.1074/Jbc.C100745200 |
0.707 |
|
| 2002 |
Lynch TW, Kosztin D, McLean MA, Schulten K, Sligar SG. Dissecting the molecular origins of specific protein-nucleic acid recognition: hydrostatic pressure and molecular dynamics. Biophysical Journal. 82: 93-8. PMID 11751298 DOI: 10.1016/S0006-3495(02)75376-9 |
0.632 |
|
| 2002 |
Unno M, Christian JF, Sjodin T, Benson DE, Macdonald ID, Sligar SG, Champion PM. Complex formation of cytochrome P450cam with Putidaredoxin. Evidence for protein-specific interactions involving the proximal thiolate ligand. The Journal of Biological Chemistry. 277: 2547-53. PMID 11706033 DOI: 10.1074/Jbc.M108917200 |
0.731 |
|
| 2002 |
Bayburt TH, Grinkova YV, Sligar SG. Self-Assembly of Discoidal Phospholipid Bilayer Nanoparticles with Membrane Scaffold Proteins Nano Letters. 2: 853-856. DOI: 10.1021/Nl025623K |
0.322 |
|
| 2002 |
Lynch TW, McLean MA, Kosztin D, Schulten K, Sligar SG. High pressure gel mobility shift analysis and molecular dynamics: Investigating specific protein-nucleic acid recognition Progress in Biotechnology. 19: 87-94. DOI: 10.1016/S0921-0423(02)80083-1 |
0.617 |
|
| 2001 |
Denisov IG, Hung SC, Weiss KE, McLean MA, Shiro Y, Park SY, Champion PM, Sligar SG. Characterization of the oxygenated intermediate of the thermophilic cytochrome P450 CYP119. Journal of Inorganic Biochemistry. 87: 215-26. PMID 11744059 DOI: 10.1016/S0162-0134(01)00328-2 |
0.732 |
|
| 2001 |
Davydov R, Makris TM, Kofman V, Werst DE, Sligar SG, Hoffman BM. Hydroxylation of camphor by reduced oxy-cytochrome P450cam: mechanistic implications of EPR and ENDOR studies of catalytic intermediates in native and mutant enzymes. Journal of the American Chemical Society. 123: 1403-15. PMID 11456714 DOI: 10.1021/Ja003583L |
0.636 |
|
| 2001 |
Deng T, Macdonald ID, Simianu MC, Sykora M, Kincaid JR, Sligar SG. Hydrogen-bonding interactions in the active sites of cytochrome P450cam and its site-directed mutants. Journal of the American Chemical Society. 123: 269-78. PMID 11456513 DOI: 10.1021/Ja001517D |
0.371 |
|
| 2001 |
Maves SA, Sligar SG. Understanding thermostability in cytochrome P450 by combinatorial mutagenesis. Protein Science : a Publication of the Protein Society. 10: 161-8. PMID 11266604 DOI: 10.1110/Ps.17601 |
0.796 |
|
| 2001 |
Denisov IG, Makris TM, Sligar SG. Cryotrapped reaction intermediates of cytochrome p450 studied by radiolytic reduction with phosphorus-32. The Journal of Biological Chemistry. 276: 11648-52. PMID 11152470 DOI: 10.1074/Jbc.M010219200 |
0.674 |
|
| 2000 |
Shank-Retzlaff ML, Sligar SG. Analyte gradient-surface plasmon resonance: a one-step method for determining kinetic rates and macromolecular binding affinities. Analytical Chemistry. 72: 4212-20. PMID 10994986 DOI: 10.1021/Ac0001030 |
0.32 |
|
| 2000 |
Park SY, Yamane K, Adachi S, Shiro Y, Weiss KE, Sligar SG. Crystallization and preliminary X-ray diffraction analysis of a cytochrome P450 (CYP119) from Sulfolobus solfataricus. Acta Crystallographica. Section D, Biological Crystallography. 56: 1173-5. PMID 10957637 DOI: 10.1107/S0907444900008234 |
0.7 |
|
| 2000 |
Lynch TW, Sligar SG. Macromolecular hydration changes associated with BamHI binding and catalysis. The Journal of Biological Chemistry. 275: 30561-5. PMID 10878000 DOI: 10.1074/Jbc.M000266200 |
0.638 |
|
| 2000 |
Schlichting I, Berendzen J, Chu K, Stock AM, Maves SA, Benson DE, Sweet RM, Ringe D, Petsko GA, Sligar SG. The catalytic pathway of cytochrome p450cam at atomic resolution. Science (New York, N.Y.). 287: 1615-22. PMID 10698731 DOI: 10.1126/Science.287.5458.1615 |
0.779 |
|
| 2000 |
Bayburt TH, Carlson JW, Sligar SG. Single molecule height measurements on a membrane protein in nanometer-scale phospholipid bilayer disks Langmuir. 16: 5993-5997. DOI: 10.1021/La991449C |
0.603 |
|
| 2000 |
Carlson JW, Bayburt T, Sligar SG. Nanopatterning phospholipid bilayers Langmuir. 16: 3927-3931. DOI: 10.1021/La990860X |
0.589 |
|
| 1999 |
Sligar SG. Nature's universal oxygenases: the cytochromes P450. Essays in Biochemistry. 34: 71-83. PMID 10730189 DOI: 10.1042/Bse0340071 |
0.409 |
|
| 1999 |
Deng TJ, Proniewicz LM, Kincaid JR, Yeom H, Macdonald ID, Sligar SG. Resonance Raman studies of cytochrome P450BM3 and its complexes with exogenous ligands. Biochemistry. 38: 13699-706. PMID 10521277 DOI: 10.1021/Bi991287J |
0.384 |
|
| 1999 |
Müller JD, McMahon BH, Chien EY, Sligar SG, Nienhaus GU. Connection between the taxonomic substates and protonation of histidines 64 and 97 in carbonmonoxy myoglobin. Biophysical Journal. 77: 1036-51. PMID 10423448 DOI: 10.1016/S0006-3495(99)76954-7 |
0.314 |
|
| 1999 |
Yeung C, Purves T, Kloss AA, Kuhl TL, Sligar S, Leckband D. CytochromecRecognition of Immobilized, Orientational Variants of Cytochromeb5: Direct Force and Equilibrium Binding Measurements Langmuir. 15: 6829-6836. DOI: 10.1021/La990019J |
0.305 |
|
| 1999 |
Carlson JW, Godfrey BJ, Sligar SG. Metal binding colloidal gold particles: A versatile scanning force microscope tip calibrator for fluid imaging Langmuir. 15: 3086-3090. DOI: 10.1021/La980749B |
0.544 |
|
| 1998 |
McLean MA, Maves SA, Weiss KE, Krepich S, Sligar SG. Characterization of a cytochrome P450 from the acidothermophilic archaea Sulfolobus solfataricus. Biochemical and Biophysical Research Communications. 252: 166-72. PMID 9813164 DOI: 10.1006/Bbrc.1998.9584 |
0.805 |
|
| 1998 |
Shank-Retzlaff ML, Raner GM, Coon MJ, Sligar SG. Membrane topology of cytochrome P450 2B4 in Langmuir-Blodgett monolayers. Archives of Biochemistry and Biophysics. 359: 82-8. PMID 9799564 DOI: 10.1006/Abbi.1998.0889 |
0.405 |
|
| 1998 |
Bayburt TH, Carlson JW, Sligar SG. Reconstitution and imaging of a membrane protein in a nanometer-size phospholipid bilayer. Journal of Structural Biology. 123: 37-44. PMID 9774543 DOI: 10.1006/Jsbi.1998.4007 |
0.654 |
|
| 1998 |
McLean MA, Di Primo C, Deprez E, Hoa GH, Sligar SG. Photoacoustic calorimetry of proteins. Methods in Enzymology. 295: 316-30. PMID 9750225 DOI: 10.1016/S0076-6879(98)95046-7 |
0.35 |
|
| 1998 |
Vidakovic M, Sligar SG, Li H, Poulos TL. Understanding the role of the essential Asp251 in cytochrome p450cam using site-directed mutagenesis, crystallography, and kinetic solvent isotope effect. Biochemistry. 37: 9211-9. PMID 9649301 DOI: 10.1021/Bi980189F |
0.362 |
|
| 1998 |
Robinson CR, Sligar SG. Changes in solvation during DNA binding and cleavage are critical to altered specificity of the EcoRI endonuclease Proceedings of the National Academy of Sciences of the United States of America. 95: 2186-2191. PMID 9482860 DOI: 10.1073/Pnas.95.5.2186 |
0.316 |
|
| 1997 |
Robinson CR, Liu Y, Thomson JA, Sturtevant JM, Sligar SG. Energetics of heme binding to native and denatured states of cytochrome b562. Biochemistry. 36: 16141-6. PMID 9405047 DOI: 10.1021/Bi971470H |
0.333 |
|
| 1997 |
Maves SA, Yeom H, McLean MA, Sligar SG. Decreased substrate affinity upon alteration of the substrate-docking region in cytochrome P450(BM-3). Febs Letters. 414: 213-8. PMID 9315688 DOI: 10.1016/S0014-5793(97)00999-X |
0.793 |
|
| 1997 |
Carlson JW, Jonas A, Sligar SG. Imaging and manipulation of high-density lipoproteins Biophysical Journal. 73: 1184-1189. PMID 9284285 DOI: 10.1016/S0006-3495(97)78150-5 |
0.581 |
|
| 1997 |
Kellner DG, Maves SA, Sligar SG. Engineering cytochrome P450s for bioremediation. Current Opinion in Biotechnology. 8: 274-8. PMID 9206006 DOI: 10.1016/S0958-1669(97)80003-1 |
0.799 |
|
| 1997 |
Benson DE, Suslick KS, Sligar SG. Reduced oxy intermediate observed in D251N cytochrome P450cam. Biochemistry. 36: 5104-7. PMID 9136869 DOI: 10.1021/Bi963170Q |
0.747 |
|
| 1997 |
Yeom H, Sligar SG. Oxygen activation by cytochrome P450(BM-3): Effects of mutating an active site acidic residue Archives of Biochemistry and Biophysics. 337: 209-216. PMID 9016815 DOI: 10.1006/Abbi.1996.9763 |
0.375 |
|
| 1997 |
Di Primo C, Deprez E, Sligar SG, Hui Bon Hoa G. Origin of the photoacoustic signal in cytochrome P-450(cam): Role of the Arg186-Asp251-Lys178 bifurcated salt bridge Biochemistry. 36: 112-118. PMID 8993324 DOI: 10.1021/Bi961508A |
0.357 |
|
| 1997 |
Rector KD, Rella CW, Hill JR, Kwok AS, Sligar SG, Chien EYT, Dlott DD, Fayer MD. Mutant and wild-type myoglobin-CO protein dynamics: Vibrational echo experiments Journal of Physical Chemistry B. 101: 1468-1475. DOI: 10.1021/Jp963226Q |
0.323 |
|
| 1997 |
Unno M, Christian JF, Benson DE, Gerber NC, Sligar SG, Champion PM. Resonance Raman investigations of cytochrome P450(cam) complexed with putidaredoxin Journal of the American Chemical Society. 119: 6614-6620. DOI: 10.1021/Ja963785A |
0.703 |
|
| 1996 |
McLean MA, Yeom H, Sligar SG. Carbon monoxide binding to cytochrome P450(BM-3): Evidence for a substrate-dependent conformational change Biochimie. 78: 700-705. PMID 9010598 DOI: 10.1016/S0300-9084(97)82527-8 |
0.374 |
|
| 1996 |
Blanke SR, Martinis SA, Sligar SG, Hager LP, Rux JJ, Dawson JH. Probing the heme iron coordination structure of alkaline chloroperoxidase. Biochemistry. 35: 14537-43. PMID 8931550 DOI: 10.1021/Bi961512M |
0.378 |
|
| 1996 |
Martinis SA, Blanke SR, Hager LP, Sligar SG, Hoa GH, Rux JJ, Dawson JH. Probing the heme iron coordination structure of pressure-induced cytochrome P420cam. Biochemistry. 35: 14530-6. PMID 8931549 DOI: 10.1021/Bi961511U |
0.374 |
|
| 1996 |
Jiang M, Nölting B, Stayton PS, Sligar SG. Surface-Linked Molecular Monolayers of an Engineered Myoglobin: Structure, Stability, and Function Langmuir. 12: 1278-1283. DOI: 10.1021/La950258G |
0.36 |
|
| 1996 |
Firestone MA, Shank ML, Sligar SG, Bohn PW. Film architecture in biomolecular assemblies. Effect of linker on the orientation of genetically engineered surface-bound proteins Journal of the American Chemical Society. 118: 9033-9041. DOI: 10.1021/Ja961046O |
0.307 |
|
| 1996 |
Scott JR, Fairris JL, McLean M, Wang K, Sligar SG, Durham B, Millett F. Intramolecular electron-transfer reactions of cytochrome b5 covalently bonded to ruthenium(II) polypyridine complexes: Reorganizational energy and pressure effects Inorganica Chimica Acta. 243: 193-200. DOI: 10.1016/0020-1693(95)04907-X |
0.303 |
|
| 1996 |
Zhu L, Zhong G, Unno M, Sligar SG, Champion PM. Femtosecond coherence spectroscopy of heme proteins Biospectroscopy. 2: 301-309. DOI: 10.1002/(Sici)1520-6343(1996)2:5<301::Aid-Bspy3>3.0.Co;2-7 |
0.312 |
|
| 1995 |
Durham B, Fairris JL, McLean M, Millett F, Scott JR, Sligar SG, Willie A. Electron transfer from cytochrome b5 to cytochrome c Journal of Bioenergetics and Biomembranes. 27: 331-340. PMID 8847346 DOI: 10.1007/Bf02110102 |
0.315 |
|
| 1995 |
Deprez E, Gerber NC, Di Primo C, Douzou P, Sligar SG, Hui Bon Hoa G. Electrostatic control of the substrate access channel in cytochrome P-450cam. Biochemistry. 33: 14464-8. PMID 7981206 DOI: 10.1021/Bi00252A012 |
0.42 |
|
| 1995 |
Loida PJ, Sligar SG, Paulsen MD, Arnold GE, Ornstein RL. Stereoselective hydroxylation of norcamphor by cytochrome P450cam. Experimental verification of molecular dynamics simulations. The Journal of Biological Chemistry. 270: 5326-30. PMID 7890644 DOI: 10.1074/Jbc.270.10.5326 |
0.314 |
|
| 1995 |
Tian WD, Wells AV, Champion PM, Di Primo C, Gerber N, Sligar SG. Measurements of CO geminate recombination in cytochromes P450 and P420. The Journal of Biological Chemistry. 270: 8673-9. PMID 7721770 DOI: 10.1074/Jbc.270.15.8673 |
0.427 |
|
| 1995 |
Abadan Y, Chien EY, Chu K, Eng CD, Nienhaus GU, Sligar SG. Ligand binding to heme proteins. V. Light-induced relaxation in proximal mutants L89I and H97F of carbonmonoxymyoglobin. Biophysical Journal. 68: 2497-504. PMID 7647252 DOI: 10.1016/S0006-3495(95)80432-7 |
0.334 |
|
| 1995 |
Hernan RA, Sligar SG. Tetrameric hemoglobin expressed in Escherichia coli: Evidence of heterogeneous subunit assembly Journal of Biological Chemistry. 270: 26257-26264. PMID 7592833 DOI: 10.1074/Jbc.270.44.26257 |
0.337 |
|
| 1995 |
Yeom H, Sligar SG, Li H, Poulos TL, Fulco AJ. The role of Thr268 in oxygen activation of cytochrome P450BM-3 Biochemistry. 34: 14733-14740. PMID 7578081 DOI: 10.1021/Bi00045A014 |
0.377 |
|
| 1995 |
Mclean MA, Sligar SG. Thermodynamic Characterization of the Interactions between Cytochrome b5 and Cytochrome c Biochemical and Biophysical Research Communications. 215: 316-320. PMID 7575608 DOI: 10.1006/Bbrc.1995.2468 |
0.35 |
|
| 1994 |
Robinson CR, Sligar SG. Hydrostatic pressure reverses osmotic pressure effects on the specificity of EcoRI-DNA interactions. Biochemistry. 33: 3787-93. PMID 8142380 DOI: 10.1021/Bi00179A001 |
0.301 |
|
| 1994 |
Thériault Y, Pochapsky TC, Dalvit C, Chiu ML, Sligar SG, Wright PE. 1H and 15N resonance assignments and secondary structure of the carbon monoxide complex of sperm whale myoglobin. Journal of Biomolecular Nmr. 4: 491-504. PMID 8075538 DOI: 10.1007/Bf00156616 |
0.308 |
|
| 1994 |
Feng Y, Sligar SG, Wand AJ. Solution structure of apocytochrome b562 Nature Structural Biology. 1: 30-35. PMID 7656004 DOI: 10.1038/Nsb0194-30 |
0.337 |
|
| 1994 |
Hong HG, Jiang M, Sligar SG, Bohn PW. Cysteine-specific surface tethering of genetically engineered cytochromes for fabrication of metalloprotein nanostructures Langmuir. 10: 153-158. DOI: 10.1021/La00013A023 |
0.315 |
|
| 1994 |
Fann Y, Gerber NC, Osmulski PA, Hager LP, Sligar SG, Hoffman BM. ENDOR Determination of Heme Ligation in Chloroperoxidase and Comparison with Cytochrome P-450Cam Journal of the American Chemical Society. 116: 5989-5990. DOI: 10.1021/Ja00092A068 |
0.404 |
|
| 1994 |
Banci L, Bertini I, Marconi S, Pierattelli R, Sligar SG. Cytochrome P450 and Aromatic Bases: A 1H NMR Study Journal of the American Chemical Society. 116: 4866-4873. DOI: 10.1021/Ja00090A035 |
0.339 |
|
| 1994 |
Aikens J, Sligar SG. Kinetic Solvent Isotope Effects during Oxygen Activation by Cytochrome P-450cam Journal of the American Chemical Society. 116: 1143-1144. DOI: 10.1021/Ja00082A051 |
0.359 |
|
| 1993 |
Loida PJ, Sligar SG. Engineering cytochrome P-450cam to increase the stereospecificity and coupling of aliphatic hydroxylation. Protein Engineering. 6: 207-12. PMID 8475046 DOI: 10.1093/Protein/6.2.207 |
0.358 |
|
| 1993 |
Di Primo C, Hui Bon Hoa G, Deprez E, Douzou P, Sligar SG. Conformational dynamics of cytochrome P-450cam as monitored by photoacoustic calorimetry. Biochemistry. 32: 3671-6. PMID 8466907 DOI: 10.1021/Bi00065A021 |
0.408 |
|
| 1993 |
Lee KB, La Mar GN, Mansfield KE, Smith KM, Pochapsky TC, Sligar SG. Interpretation of hyperfine shift patterns in ferricytochromes b5 in terms of angular position of the heme: a sensitive probe for peripheral heme protein interactions. Biochimica Et Biophysica Acta. 1202: 189-99. PMID 8399380 DOI: 10.1016/0167-4838(93)90004-B |
0.325 |
|
| 1993 |
Willie A, McLean M, Liu RQ, Hilgen-Willis S, Saunders AJ, Pielak GJ, Sligar SG, Durham B, Millett F. Intracomplex electron transfer between ruthenium-65-cytochrome b5 and position-82 variants of yeast iso-1-cytochrome c. Biochemistry. 32: 7519-25. PMID 8393343 DOI: 10.1021/Bi00080A025 |
0.306 |
|
| 1993 |
Ropp JD, Gunsalus IC, Sligar SG. Cloning and expression of a member of a new cytochrome P-450 family: cytochrome P-450lin (CYP111) from Pseudomonas incognita. Journal of Bacteriology. 175: 6028-37. PMID 8376348 DOI: 10.1128/Jb.175.18.6028-6037.1993 |
0.39 |
|
| 1993 |
Braunstein DP, Chu K, Egeberg KD, Frauenfelder H, Mourant JR, Nienhaus GU, Ormos P, Sligar SG, Springer BA, Young RD. Ligand binding to heme proteins: III. FTIR studies of His-E7 and Val-E11 mutants of carbonmonoxymyoglobin. Biophysical Journal. 65: 2447-54. PMID 8312483 DOI: 10.1016/S0006-3495(93)81310-9 |
0.329 |
|
| 1993 |
Loida PJ, Sligar SG. Molecular recognition in cytochrome P-450: mechanism for the control of uncoupling reactions. Biochemistry. 32: 11530-8. PMID 8218220 DOI: 10.1021/Bi00094A009 |
0.381 |
|
| 1992 |
Wells AV, Li P, Champion PM, Martinis SA, Sligar SG. Resonance Raman investigations of Escherichia coli-expressed Pseudomonas putida cytochrome P450 and P420 Biochemistry. 31: 4384-4393. PMID 1581294 DOI: 10.1021/Bi00133A002 |
0.453 |
|
| 1992 |
Davies MD, Sligar SG. Genetic variants in the putidaredoxin-cytochrome P-450cam electron-transfer complex: identification of the residue responsible for redox-state-dependent conformers. Biochemistry. 31: 11383-9. PMID 1445875 DOI: 10.1021/Bi00161A016 |
0.343 |
|
| 1992 |
Di Primo C, Sligar SG, Hoa GH, Douzou P. A critical role of protein-bound water in the catalytic cycle of cytochrome P-450 camphor. Febs Letters. 312: 252-4. PMID 1426259 DOI: 10.1016/0014-5793(92)80946-E |
0.39 |
|
| 1992 |
Di Primo C, Hui Bon Hoa G, Douzou P, Sligar SG. Heme-pocket-hydration change during the inactivation of cytochrome P-450camphor by hydrostatic pressure. European Journal of Biochemistry. 209: 583-8. PMID 1425665 DOI: 10.1111/J.1432-1033.1992.Tb17323.X |
0.414 |
|
| 1992 |
Sligar S, Gerber N, Loida P. An integrated picture of cytochrome P450 catalysis Journal of Basic and Clinical Physiology and Pharmacology. 3. DOI: 10.1515/Jbcpp.1992.3.S1.34 |
0.364 |
|
| 1992 |
Gerber NC, Sligar SG. Catalytic mechanism of cytochrome P-450: evidence for a distal charge relay Journal of the American Chemical Society. 114: 8742-8743. DOI: 10.1021/Ja00048A081 |
0.336 |
|
| 1992 |
Bormett RW, Asher SA, Larking PJ, Gustafson WG, Ragunathan N, Freedman TB, Nafie LA, Balasubramanian S, Boxer SG, Yu NT, Genonde K, Noble RW, Springer BA, Sligar SG. Selective examination of heme protein azide ligand-distal globin interactions by vibrational circular dichroism Journal of the American Chemical Society. 114: 6864-6867. DOI: 10.1021/Ja00043A035 |
0.326 |
|
| 1991 |
Wu JZ, La Mar GN, Yu LP, Lee KB, Walker FA, Chiu ML, Sligar SG. 1H NMR study of the solution molecular and electronic structure of Escherichia coli ferricytochrome b562: evidence for S = 1/2 in equilibrium S = 5/2 spin equilibrium for intact His/Met ligation. Biochemistry. 30: 2156-65. PMID 1998676 DOI: 10.1021/Bi00222A020 |
0.318 |
|
| 1991 |
Stayton PS, Sligar SG. Structural microheterogeneity of a tryptophan residue required for efficient biological electron transfer between putidaredoxin and cytochrome P-450(cam) Biochemistry. 30: 1845-1851. PMID 1993199 DOI: 10.1021/Bi00221A017 |
0.412 |
|
| 1991 |
Feng YQ, Wand AJ, Sligar SG. 1H and 15N NMR resonance assignments and preliminary structural characterization of Escherichia coli apocytochrome b562. Biochemistry. 30: 7711-7. PMID 1868051 DOI: 10.1021/Bi00245A007 |
0.303 |
|
| 1991 |
Sligar SG, Filipovic D, Stayton PS. Mutagenesis of cytochromes P450cam and b5 Methods in Enzymology. 206: 31-49. PMID 1784217 DOI: 10.1016/0076-6879(91)06074-D |
0.386 |
|
| 1991 |
Frauenfelder H, Sligar SG, Wolynes PG. The energy landscapes and motions of proteins. Science (New York, N.Y.). 254: 1598-603. PMID 1749933 DOI: 10.1126/Science.1749933 |
0.312 |
|
| 1991 |
Raag R, Martinis SA, Sligar SG, Poulos TL. Crystal structure of the cytochrome P-450(CAM) active site mutant Thr252Ala Biochemistry. 30: 11420-11429. PMID 1742281 DOI: 10.2210/Pdb2Cp4/Pdb |
0.404 |
|
| 1991 |
Rodgers KK, Sligar SG. Mapping electrostatic interactions in macromolecular associations. Journal of Molecular Biology. 221: 1453-60. PMID 1658337 DOI: 10.1016/0022-2836(91)90945-3 |
0.367 |
|
| 1991 |
Qin L, Rodgers KK, Sligar SG. Electron Transfer between Cytochrome B5 Surface Mutants and Cytochrome C Molecular Crystals and Liquid Crystals. 194: 311-316. DOI: 10.1080/00268949108041181 |
0.31 |
|
| 1991 |
Atkins WM, Sligar SG. Protein engineering for studying enzyme catalytic mechanism Current Opinion in Structural Biology. 1: 611-616. DOI: 10.1016/S0959-440X(05)80085-5 |
0.364 |
|
| 1990 |
Hui Bon Hoa G, Di Primo C, Geze M, Douzou P, Kornblatt JA, Sligar SG. The formation of cytochrome P-450 from cytochrome P-420 is promoted by spermine. Biochemistry. 29: 6810-5. PMID 2397214 DOI: 10.1021/Bi00481A008 |
0.4 |
|
| 1990 |
Lee KB, La Mar GN, Kehres LA, Fujinari EM, Smith KM, Pochapsky TC, Sligar SG. 1H NMR study of the influence of hydrophobic contacts on protein-prosthetic group recognition in bovine and rat ferricytochrome b5. Biochemistry. 29: 9623-31. PMID 2271605 DOI: 10.1021/Bi00493A017 |
0.341 |
|
| 1990 |
Di Primo C, Hui Bon Hoa G, Douzou P, Sligar S. Effect of the tyrosine 96 hydrogen bond on the inactivation of cytochrome P-450cam induced by hydrostatic pressure. European Journal of Biochemistry. 193: 383-6. PMID 2226459 DOI: 10.1111/J.1432-1033.1990.Tb19350.X |
0.405 |
|
| 1990 |
Stayton PS, Sligar SG. The cytochrome p-450cam binding surface as defined by site-directed mutagenesis and electrostatic modeling Biochemistry®. 29: 7381-7386. PMID 2223769 DOI: 10.1021/Bi00484A005 |
0.42 |
|
| 1990 |
Atkins WM, Sligar SG. Tyrosine-96 as a natural spectroscopic probe of the cytochrome P-450cam active site. Biochemistry. 29: 1271-5. PMID 2182119 DOI: 10.1021/Bi00457A024 |
0.37 |
|
| 1990 |
Gerber NC, Horiuchi T, Koga H, Sligar SG. Identification of 2Fe-2S cysteine ligands in putidaredoxin. Biochemical and Biophysical Research Communications. 169: 1016-20. PMID 2163624 DOI: 10.1016/0006-291X(90)91995-5 |
0.305 |
|
| 1990 |
Davies MD, Qin L, Beck JL, Suslick KS, Koga H, Horiuchi T, Sligar SG. Putidaredoxin reduction of cytochrome P-450cam: dependence of electron transfer on the identity of putidaredoxin's C-terminal amino acid Journal of the American Chemical Society. 112: 7396-7398. DOI: 10.1021/Ja00176A050 |
0.338 |
|
| 1989 |
Stayton PS, Poulos TL, Sligar SG. Putidaredoxin competitively inhibits cytochrome b5-cytochrome P-450cam association: A proposed molecular model for a cytochrome P-450cam electron-transfer complex Biochemistry. 28: 8201-8205. PMID 2690937 DOI: 10.1021/Bi00446A035 |
0.422 |
|
| 1989 |
Hui Bon Hoa G, Di Primo C, Dondaine I, Sligar SG, Gunsalus IC, Douzou P. Conformational changes of cytochromes P-450cam and P-450lin induced by high pressure. Biochemistry. 28: 651-6. PMID 2578028 DOI: 10.1021/Bi00428A035 |
0.408 |
|
| 1989 |
Martinis SA, Sotiriou C, Chang CK, Sligar SG. Characterization of cytochrome b5 reconstituted with a ferric chlorin and a ferric oxochlorin Biochemistry. 28: 879-884. PMID 2540809 DOI: 10.1021/Bi00428A071 |
0.324 |
|
| 1989 |
Martinis SA, Atkins WM, Stayton PS, Sligar SG. A conserved residue of cytochrome P-450 is involved in heme-oxygen stability and activation Journal of the American Chemical Society. 111: 9252-9253. DOI: 10.1021/Ja00208A031 |
0.376 |
|
| 1989 |
Atkins WM, Sligar SG. Molecular recognition in cytochrome P-450: alteration of regioselective alkane hydroxylation via protein engineering Journal of the American Chemical Society. 111: 2715-2717. DOI: 10.1021/Ja00189A057 |
0.376 |
|
| 1988 |
Atkins WM, Sligar SG. Deuterium isotope effects in norcamphor metabolism by cytochrome P-450cam: kinetic evidence for the two-electron reduction of a high-valent iron-oxo intermediate. Biochemistry. 27: 1610-6. PMID 3284586 DOI: 10.1021/Bi00405A033 |
0.38 |
|
| 1988 |
Olson JS, Mathews AJ, Rohlfs RJ, Springer BA, Egeberg KD, Sligar SG, Tame J, Renaud JP, Nagai K. The role of the distal histidine in myoglobin and haemoglobin. Nature. 336: 265-6. PMID 3057383 DOI: 10.1038/336265A0 |
0.321 |
|
| 1988 |
Rodgers KK, Pochapsky TC, Sligar SG. Probing the mechanisms of macromolecular recognition: The cytochrome b 5-cytochrome c complex Science. 240: 1657-1659. PMID 2837825 DOI: 10.1126/Science.2837825 |
0.331 |
|
| 1987 |
Sligar SG, Egeberg KD, Sage JT, Morikis D, Champion PM. Alteration of heme axial ligands by site-directed mutagenesis: a cytochrome becomes a catalytic demethylase Journal of the American Chemical Society. 109: 7896-7897. DOI: 10.1021/Ja00259A056 |
0.301 |
|
| 1987 |
Atkins WM, Sligar SG. Metabolic switching in cyctochrome P-450cam: deuterium isotope effects on regiospecificity and the monooxygenase/oxidase ratio Journal of the American Chemical Society. 109: 3754-3760. DOI: 10.1021/Ja00246A038 |
0.319 |
|
| 1986 |
Beck von Bodman S, Schuler MA, Jollie DR, Sligar SG. Synthesis, bacterial expression, and mutagenesis of the gene coding for mammalian cytochrome b5 Proceedings of the National Academy of Sciences of the United States of America. 83: 9443-9447. PMID 3540940 DOI: 10.1073/Pnas.83.24.9443 |
0.371 |
|
| 1986 |
Fisher MT, White RE, Sligar SG. Pressure dissociation of a protein-protein electron-transfer complex Journal of the American Chemical Society. 108: 6835-6837. DOI: 10.1021/Ja00281A079 |
0.301 |
|
| 1985 |
Fisher MT, Sligar SG. Tyrosine motions in relation to the ferric spin equilibrium of cytochrome P-450cam Biochemistry. 24: 6696-6701. PMID 4084552 DOI: 10.1021/Bi00344A059 |
0.359 |
|
| 1985 |
Fisher MT, Scarlata SF, Sligar SG. High-pressure investigations of cytochrome P-450 spin and substrate binding equilibria Archives of Biochemistry and Biophysics. 240: 456-463. PMID 2990349 DOI: 10.1016/0003-9861(85)90050-5 |
0.356 |
|
| 1984 |
White RE, McCarthy MB, Egeberg KD, Sligar SG. Regioselectivity in the cytochromes P-450: control by protein constraints and by chemical reactivities. Archives of Biochemistry and Biophysics. 228: 493-502. PMID 6696444 DOI: 10.1016/0003-9861(84)90015-8 |
0.426 |
|
| 1984 |
Sligar SG, Gelb MH, Heimbrook DC. Bio-organic chemistry and cytochrome P-450-dependent catalysis. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 14: 63-86. PMID 6372267 DOI: 10.3109/00498258409151399 |
0.498 |
|
| 1982 |
Backes WL, Sligar SG, Schenkman JB. Kinetics of hepatic cytochrome P-450 reduction: correlation with spin state of the ferric heme. Biochemistry. 21: 1324-30. PMID 7074090 DOI: 10.1021/Bi00535A034 |
0.329 |
|
| 1982 |
Gelb MH, Heimbrook DC, Mälkönen P, Sligar SG. Stereochemistry and deuterium isotope effects in camphor hydroxylation by the cytochrome P450cam monoxygenase system. Biochemistry. 21: 370-7. PMID 7074020 DOI: 10.1021/Bi00531A026 |
0.489 |
|
| 1982 |
Gelb MH, Malkonen P, Sligar SG. Cytochrome P450cam catalyzed epoxidation of dehydrocamphor. Biochemical and Biophysical Research Communications. 104: 853-8. PMID 7073732 DOI: 10.1016/0006-291X(82)91327-4 |
0.557 |
|
| 1982 |
Gelb MH, Toscano WA, Sligar SG. Chemical mechanisms for cytochrome P-450 oxidation: spectral and catalytic properties of a manganese-substituted protein. Proceedings of the National Academy of Sciences of the United States of America. 79: 5758-62. PMID 6964386 DOI: 10.1073/Pnas.79.19.5758 |
0.584 |
|
| 1982 |
Kennedy KA, Sligar SG, Polomski L, Sartorelli AC. Metabolic activation of mitomycin C by liver microsomes and nuclei Biochemical Pharmacology. 31: 2011-2016. PMID 6810899 DOI: 10.1016/0006-2952(82)90414-2 |
0.364 |
|
| 1982 |
Gelb M, Heimbrook D, Malkonen P, Sligar S. Corrections - Stereochemistry and Deuterium Effects in Camphor Hydroxylation by the Cytochrome P450cam Monoxygenase System Biochemistry. 21: 3036-3036. DOI: 10.1021/Bi00541A607 |
0.477 |
|
| 1981 |
Backes WL, Sligar SG, Schenkman JB. Cytochrome P-450 reduction exhibits burst kinetics. Biochemical and Biophysical Research Communications. 97: 860-7. PMID 7470153 DOI: 10.1016/0006-291X(80)91456-4 |
0.336 |
|
| 1981 |
Gould PV, Gelb MH, Sligar SG. Interaction of 5-bromocamphor with cytochrome P-450 cam. Production of 5-ketocamphor from a mixed spin state hemoprotein. The Journal of Biological Chemistry. 256: 6686-91. PMID 7240237 |
0.537 |
|
| 1981 |
Heimbrook DC, Sligar SG. Multiple mechanisms of cytochrome P450-catalyzed substrate hydroxylations. Biochemical and Biophysical Research Communications. 99: 530-5. PMID 7236281 DOI: 10.1016/0006-291X(81)91777-0 |
0.375 |
|
| 1981 |
Schenkman JB, Sligar SG, Cinti DL. Substrate interaction with cytochrome P-450. Pharmacology & Therapeutics. 12: 43-71. PMID 7019934 DOI: 10.1016/0163-7258(81)90075-9 |
0.384 |
|
| 1980 |
Sligar SG, Kennedy KA, Pearson DC. Chemical mechanisms for cytochrome P-450 hydroxylation: Evidence for acylation of heme-bound dioxygen Proceedings of the National Academy of Sciences of the United States of America. 77: 1240-1244. PMID 6929480 DOI: 10.1073/Pnas.77.3.1240 |
0.336 |
|
| 1980 |
Gibson GG, Sligar SG, Cinti DL, Schenkman JB. Purified cytochrome P-450: spin-state control of the haemoprotein redox potential [proceedings]. Biochemical Society Transactions. 8: 101-2. PMID 6245949 DOI: 10.1042/Bst0080101 |
0.327 |
|
| 1980 |
Gibson GG, Cinti DL, Sligar SG, Schenkman JB. The effect of microsomal lipids on the spin state of purified de-lipidated cytochrome P-450 [proceedings]. Biochemical Society Transactions. 7: 1289-90. PMID 231531 DOI: 10.1042/Bst0071289 |
0.359 |
|
| 1980 |
Sligar SG, Cinti DL, Gibson GG, Schenkman JB. Spin state control of the hepatic cytochrome P450 redox potential. Biochemical and Biophysical Research Communications. 90: 925-32. PMID 228675 DOI: 10.1016/0006-291X(79)91916-8 |
0.383 |
|
| 1980 |
Sligar SG, Kennedy KA, Pearson DC. Tetrahedral Intermediates In Cytochrome P450 Hydroxylations Microsomes, Drug Oxidations and Chemical Carcinogenesis. 391-393. DOI: 10.1016/B978-0-12-187701-9.50078-4 |
0.405 |
|
| 1980 |
Sligar S, Cinti DC, Gibson GG, Schenkman JB. Spin States And Redox Potentials Of Hepatic Cytochrome P450 Microsomes, Drug Oxidations and Chemical Carcinogenesis. 175-178. DOI: 10.1016/B978-0-12-187701-9.50034-6 |
0.356 |
|
| 1980 |
Jansson I, Gibson GG, Sligar SG, Cinti DL, Schenkman JB. Influence Of Substrates Of Hepatic Mixed Function Oxidases On Spin Equilibrium Of Cytochrome P-450 Microsomes, Drug Oxidations and Chemical Carcinogenesis. 139-142. DOI: 10.1016/B978-0-12-187701-9.50025-5 |
0.379 |
|
| 1979 |
Sligar SG, Gunsalus IC. Proton coupling in the cytochrome P-450 spin and redox equilibria. Biochemistry. 18: 2290-5. PMID 444456 DOI: 10.1021/Bi00578A024 |
0.319 |
|
| 1978 |
Gunsalus IC, Sligar SG. Oxygen reduction by the P450 monoxygenase systems. Advances in Enzymology and Related Areas of Molecular Biology. 47: 1-44. PMID 364937 DOI: 10.1002/9780470122921.Ch1 |
0.317 |
|
| 1977 |
Gunsalus IC, Sligar SG, Nordlund T, Frauenfelder H. Oxygen sensing heme proteins: monoxygenases, myoglobin and hemoglobin. Advances in Experimental Medicine and Biology. 78: 37-50. PMID 331893 DOI: 10.1007/978-1-4615-9035-4_3 |
0.369 |
|
| 1977 |
Sligar SG. Coupling of spin, substrate, and redox equilibria in cytochrome P450. Biochemistry. 15: 5399-406. PMID 187215 DOI: 10.1021/Bi00669A029 |
0.332 |
|
| 1976 |
Hanson LK, Eaton WA, Sligar SG, Gunsalus IC, Gouterman M, Connell CR. Letter: Origin of the anomalous Soret spectra of carboxycytochrome P-450. Journal of the American Chemical Society. 98: 2672-4. PMID 1262660 DOI: 10.1021/Ja00425A050 |
0.358 |
|
| 1976 |
Gunsalus IC, Sligar SG. Redox regulation of cytochrome P450cam mixed function oxidation by putidaredoxin and camphor ligation. Biochimie. 58: 143-7. PMID 953050 DOI: 10.1016/S0300-9084(76)80364-1 |
0.368 |
|
| 1975 |
GUNSALUS IC, SLIGAR SG, DEBRUNNER PG. Product Formation from Ferrous Oxy-Cytochrome P-450 Biochemical Society Transactions. 3: 821-825. DOI: 10.1042/Bst0030821 |
0.628 |
|
| 1974 |
Sligar SG, Debrunner PG, Lipscomb JD, Namtvedt MJ, Gunsalus IC. A role of the putidaredoxin COOH-terminus in P-450cam (cytochrome m) hydroxylations. Proceedings of the National Academy of Sciences of the United States of America. 71: 3906-10. PMID 4530269 DOI: 10.1073/Pnas.71.10.3906 |
0.592 |
|
| 1974 |
Sligar SG, Lipscomb JD, Debrunner PG, Gunsalus IC. Superoxide anion production by the autoxidation of cytochrome P450cam. Biochemical and Biophysical Research Communications. 61: 290-6. PMID 4441397 DOI: 10.1016/0006-291X(74)90565-8 |
0.579 |
|
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