| Year |
Citation |
Score |
| 2022 |
Mermans D, Nicolaus F, Fleisch K, von Heijne G. Cotranslational folding and assembly of the dimeric inner membrane protein EmrE. Proceedings of the National Academy of Sciences of the United States of America. 119: e2205810119. PMID 35994672 DOI: 10.1073/pnas.2205810119 |
0.57 |
|
| 2022 |
Nicolaus F, Ibrahimi F, den Besten A, von Heijne G. Upstream charged and hydrophobic residues impact the timing of membrane insertion of transmembrane helices. Febs Letters. PMID 35038773 DOI: 10.1002/1873-3468.14286 |
0.518 |
|
| 2021 |
von Heijne G. Molten globules lure transmembrane helices away from the membrane. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34433673 DOI: 10.1073/pnas.2112899118 |
0.505 |
|
| 2021 |
von Heijne G. Introduction to the Theme on Membrane Channels. Annual Review of Biochemistry. 90: 503-505. PMID 34153216 DOI: 10.1146/annurev-biochem-010421-023239 |
0.422 |
|
| 2021 |
Sandhu H, Hedman R, Cymer F, Kudva R, Ismail N, von Heijne G. Cotranslational translocation and folding of a periplasmic protein domain in Escherichia coli. Journal of Molecular Biology. 167047. PMID 33989648 DOI: 10.1016/j.jmb.2021.167047 |
0.456 |
|
| 2021 |
Nicolaus F, Metola A, Mermans D, Liljenström A, Krč A, Abdullahi SM, Zimmer M, Miller TF, von Heijne G. Residue-by-residue analysis of cotranslational membrane protein integration in vivo. Elife. 10. PMID 33554862 DOI: 10.7554/eLife.64302 |
0.523 |
|
| 2019 |
Andersson A, Kudva R, Magoulopoulou A, Lejarre Q, Lara P, Xu P, Goel S, Pissi J, Ru X, Hessa T, Wahlgren M, von Heijne G, Nilsson I, Tellgren-Roth Å. Membrane integration and topology of RIFIN and STEVOR proteins of the Plasmodium falciparum parasite. The Febs Journal. PMID 31821735 DOI: 10.1111/febs.15171 |
0.488 |
|
| 2019 |
Lee S, Lee H, Yoo S, Leva R, van der Laan M, von Heijne G, Kim H. The Mgr2 subunit of the TIM23 complex regulates membrane insertion of marginal stop-transfer signals in the mitochondrial inner membrane. Febs Letters. PMID 31764998 DOI: 10.1002/1873-3468.13692 |
0.4 |
|
| 2019 |
Almagro Armenteros JJ, Salvatore M, Emanuelsson O, Winther O, von Heijne G, Elofsson A, Nielsen H. Detecting sequence signals in targeting peptides using deep learning. Life Science Alliance. 2. PMID 31570514 DOI: 10.26508/lsa.201900429 |
0.544 |
|
| 2019 |
Seurig M, Ek M, von Heijne G, Fluman N. Dynamic membrane topology in an unassembled membrane protein. Nature Chemical Biology. PMID 31501590 DOI: 10.1038/s41589-019-0356-9 |
0.542 |
|
| 2019 |
Lara P, Tellgren-Roth Å, Behesti H, Horn Z, Schiller N, Enquist K, Cammenberg M, Liljenström A, Hatten ME, von Heijne G, Nilsson I. Murine astrotactins 1 and 2 have similar membrane topology and mature via endoproteolytic cleavage catalyzed by signal peptidase. The Journal of Biological Chemistry. PMID 30696770 DOI: 10.1074/jbc.RA118.007093 |
0.413 |
|
| 2018 |
Notari L, Martínez-Carranza M, Farías-Rico JA, Stenmark P, von Heijne G. Cotranslational Folding of a Pentarepeat β-Helix Protein. Journal of Molecular Biology. 430: 5196-5206. PMID 30539762 DOI: 10.1016/J.Jmb.2018.10.016 |
0.351 |
|
| 2018 |
Bañó-Polo M, Baeza-Delgado C, Tamborero S, Hazel A, Grau B, Nilsson I, Whitley P, Gumbart JC, von Heijne G, Mingarro I. Transmembrane but not soluble helices fold inside the ribosome tunnel. Nature Communications. 9: 5246. PMID 30531789 DOI: 10.1038/S41467-018-07554-7 |
0.711 |
|
| 2018 |
Kudva R, Tian P, Pardo-Avila F, Carroni M, Best R, Bernstein HD, von Heijne G. The shape of the ribosome exit tunnel affects cotranslational protein folding. Elife. 7. PMID 30475203 DOI: 10.7554/eLife.36326 |
0.342 |
|
| 2018 |
Tian P, Steward A, Kudva R, Su T, Shilling PJ, Nickson AA, Hollins JJ, Beckmann R, von Heijne G, Clarke J, Best RB. Folding pathway of an Ig domain is conserved on and off the ribosome. Proceedings of the National Academy of Sciences of the United States of America. PMID 30413621 DOI: 10.1073/Pnas.1810523115 |
0.304 |
|
| 2018 |
Niesen MJM, Müller-Lucks A, Hedman R, von Heijne G, Miller TF. Forces on Nascent Polypeptides during Membrane Insertion and Translocation via the Sec Translocon. Biophysical Journal. PMID 30366631 DOI: 10.1016/J.Bpj.2018.10.002 |
0.433 |
|
| 2018 |
Farías-Rico JA, Ruud Selin F, Myronidi I, Frühauf M, von Heijne G. Effects of protein size, thermodynamic stability, and net charge on cotranslational folding on the ribosome. Proceedings of the National Academy of Sciences of the United States of America. PMID 30224455 DOI: 10.1073/pnas.1812756115 |
0.311 |
|
| 2018 |
Orrell KE, Tellgren-Roth Å, Di Bernardo M, Zhang Z, Cuviello F, Lundqvist J, von Heijne G, Nilsson I, Melnyk RA. Direct detection of membrane-inserting fragments defines the translocation pores of a family of pathogenic toxins. Journal of Molecular Biology. PMID 29990469 DOI: 10.1016/j.jmb.2018.07.001 |
0.494 |
|
| 2018 |
von Heijne G. Membrane protein serendipity. The Journal of Biological Chemistry. 293: 3470-3476. PMID 29523692 DOI: 10.1074/jbc.X118.001958 |
0.473 |
|
| 2017 |
Fluman N, Tobiasson V, von Heijne G. Stable membrane orientations of small dual-topology membrane proteins. Proceedings of the National Academy of Sciences of the United States of America. PMID 28698365 DOI: 10.1073/pnas.1706905114 |
0.808 |
|
| 2017 |
Renault H, De Marothy M, Jonasson G, Lara P, Nelson DR, Nilsson I, André F, von Heijne G, Werck-Reichhart D. Gene duplication leads to altered membrane topology of a cytochrome P450 enzyme in seed plants. Molecular Biology and Evolution. PMID 28505373 DOI: 10.1093/molbev/msx160 |
0.384 |
|
| 2017 |
Ulmschneider MB, Ulmschneider JP, Freites JA, von Heijne G, Tobias DJ, White SH. Transmembrane helices containing a charged arginine are thermodynamically stable. European Biophysics Journal : Ebj. PMID 28409218 DOI: 10.1007/S00249-017-1206-X |
0.443 |
|
| 2016 |
Mishima E, Sato Y, Nanatani K, Hoshi N, Lee JK, Schiller N, von Heijne G, Sakaguchi M, Uozumi N. The topogenic function of S4 promotes membrane insertion of the voltage-sensor domain in the KvAP channel. The Biochemical Journal. PMID 27694387 DOI: 10.1042/BCJ20160746 |
0.358 |
|
| 2016 |
Stone TA, Schiller N, Workewych N, von Heijne G, Deber CM. Hydrophobic clusters raise the threshold hydrophilicity for insertion of transmembrane sequences in vivo. Biochemistry. PMID 27620701 DOI: 10.1021/acs.biochem.6b00650 |
0.453 |
|
| 2016 |
Öjemalm K, Higuchi T, Lara P, Lindahl E, Suga H, von Heijne G. Energetics of side-chain snorkeling in transmembrane helices probed by nonproteinogenic amino acids. Proceedings of the National Academy of Sciences of the United States of America. PMID 27601675 DOI: 10.1073/Pnas.1606776113 |
0.469 |
|
| 2016 |
Schibich D, Gloge F, Pöhner I, Björkholm P, Wade RC, von Heijne G, Bukau B, Kramer G. Global profiling of SRP interaction with nascent polypeptides. Nature. PMID 27487212 DOI: 10.1038/Nature19070 |
0.494 |
|
| 2016 |
Baeza-Delgado C, von Heijne G, Marti-Renom MA, Mingarro I. Biological insertion of computationally designed short transmembrane segments. Scientific Reports. 6: 23397. PMID 26987712 DOI: 10.1038/Srep23397 |
0.751 |
|
| 2016 |
Marino J, von Heijne G, Beckmann R. Small protein domains fold inside the ribosome exit tunnel. Febs Letters. PMID 26879042 DOI: 10.1002/1873-3468.12098 |
0.324 |
|
| 2015 |
Nilsson OB, Hedman R, Marino J, Wickles S, Bischoff L, Johansson M, Müller-Lucks A, Trovato F, Puglisi JD, O'Brien EP, Beckmann R, von Heijne G. Cotranslational Protein Folding inside the Ribosome Exit Tunnel. Cell Reports. 12: 1533-40. PMID 26321634 DOI: 10.1016/J.Celrep.2015.07.065 |
0.3 |
|
| 2015 |
Stone TA, Schiller N, von Heijne G, Deber CM. Hydrophobic blocks facilitate lipid compatibility and translocon recognition of transmembrane protein sequences. Biochemistry. 54: 1465-73. PMID 25635746 DOI: 10.1021/bi5014886 |
0.378 |
|
| 2015 |
Ismail N, Hedman R, Lindén M, von Heijne G. Charge-driven dynamics of nascent-chain movement through the SecYEG translocon. Nature Structural & Molecular Biology. 22: 145-9. PMID 25558985 DOI: 10.1038/nsmb.2940 |
0.304 |
|
| 2015 |
Botelho SC, Enquist K, von Heijne G, Draheim RR. Differential repositioning of the second transmembrane helices from E. coli Tar and EnvZ upon moving the flanking aromatic residues. Biochimica Et Biophysica Acta. 1848: 615-21. PMID 25445668 DOI: 10.1016/J.Bbamem.2014.11.017 |
0.357 |
|
| 2015 |
Vargas-Uribe M, Rodnin MV, Öjemalm K, Holgado A, Kyrychenko A, Nilsson I, Posokhov YO, Makhatadze G, von Heijne G, Ladokhin AS. Thermodynamics of Membrane Insertion and Refolding of the Diphtheria Toxin T-Domain. The Journal of Membrane Biology. 248: 383-94. PMID 25281329 DOI: 10.1007/S00232-014-9734-0 |
0.411 |
|
| 2015 |
Cymer F, von Heijne G, White SH. Mechanisms of integral membrane protein insertion and folding. Journal of Molecular Biology. 427: 999-1022. PMID 25277655 DOI: 10.1016/J.Jmb.2014.09.014 |
0.514 |
|
| 2015 |
Nilsson I, Lara P, Hessa T, Johnson AE, von Heijne G, Karamyshev AL. The code for directing proteins for translocation across ER membrane: SRP cotranslationally recognizes specific features of a signal sequence. Journal of Molecular Biology. 427: 1191-201. PMID 24979680 DOI: 10.1016/J.Jmb.2014.06.014 |
0.326 |
|
| 2014 |
Ulmschneider MB, Ulmschneider JP, Schiller N, Wallace BA, von Heijne G, White SH. Spontaneous transmembrane helix insertion thermodynamically mimics translocon-guided insertion. Nature Communications. 5: 4863. PMID 25204588 DOI: 10.1038/Ncomms5863 |
0.429 |
|
| 2014 |
Björkholm P, Ernst AM, Hacke M, Wieland F, Brügger B, von Heijne G. Identification of novel sphingolipid-binding motifs in mammalian membrane proteins. Biochimica Et Biophysica Acta. 1838: 2066-70. PMID 24796501 DOI: 10.1016/j.bbamem.2014.04.026 |
0.364 |
|
| 2014 |
Virkki M, Boekel C, Illergård K, Peters C, Shu N, Tsirigos KD, Elofsson A, von Heijne G, Nilsson I. Large tilts in transmembrane helices can be induced during tertiary structure formation. Journal of Molecular Biology. 426: 2529-38. PMID 24793448 DOI: 10.1016/J.Jmb.2014.04.020 |
0.743 |
|
| 2014 |
Cymer F, Ismail N, von Heijne G. Weak pulling forces exerted on Nin-orientated transmembrane segments during co-translational insertion into the inner membrane of Escherichia coli. Febs Letters. 588: 1930-4. PMID 24726730 DOI: 10.1016/j.febslet.2014.03.050 |
0.48 |
|
| 2014 |
Lloris-Garcerá P, Seppälä S, Slusky JS, Rapp M, von Heijne G. Why have small multidrug resistance proteins not evolved into fused, internally duplicated structures? Journal of Molecular Biology. 426: 2246-54. PMID 24690367 DOI: 10.1016/j.jmb.2014.03.012 |
0.779 |
|
| 2014 |
Söderström B, Skoog K, Blom H, Weiss DS, von Heijne G, Daley DO. Disassembly of the divisome in Escherichia coli: evidence that FtsZ dissociates before compartmentalization. Molecular Microbiology. 92: 1-9. PMID 24506818 DOI: 10.1111/mmi.12534 |
0.319 |
|
| 2014 |
Ismail N, Hedman R, Schiller N, Cymer F, Nilsson O, Von Heijne G. Arrest peptides as force sensors to study co-translational membrane protein biogenesis Regulatory Nascent Polypeptides. 279-290. DOI: 10.1007/978-4-431-55052-5_16 |
0.326 |
|
| 2013 |
Reithinger JH, Yim C, Park K, Björkholm P, von Heijne G, Kim H. A short C-terminal tail prevents mis-targeting of hydrophobic mitochondrial membrane proteins to the ER. Febs Letters. 587: 3480-6. PMID 24055247 DOI: 10.1016/j.febslet.2013.08.041 |
0.313 |
|
| 2013 |
Cymer F, von Heijne G. Cotranslational folding of membrane proteins probed by arrest-peptide-mediated force measurements. Proceedings of the National Academy of Sciences of the United States of America. 110: 14640-5. PMID 23959879 DOI: 10.1073/pnas.1306787110 |
0.575 |
|
| 2013 |
Lloris-Garcerá P, Slusky JS, Seppälä S, Prieß M, Schäfer LV, von Heijne G. In vivo trp scanning of the small multidrug resistance protein EmrE confirms 3D structure models'. Journal of Molecular Biology. 425: 4642-51. PMID 23920359 DOI: 10.1016/j.jmb.2013.07.039 |
0.688 |
|
| 2013 |
Nørholm MH, Toddo S, Virkki MT, Light S, von Heijne G, Daley DO. Improved production of membrane proteins in Escherichia coli by selective codon substitutions. Febs Letters. 587: 2352-8. PMID 23769986 DOI: 10.1016/J.Febslet.2013.05.063 |
0.33 |
|
| 2013 |
Ojemalm K, Botelho SC, Stüdle C, von Heijne G. Quantitative analysis of SecYEG-mediated insertion of transmembrane α-helices into the bacterial inner membrane. Journal of Molecular Biology. 425: 2813-22. PMID 23659793 DOI: 10.1016/j.jmb.2013.04.025 |
0.513 |
|
| 2013 |
Botelho SC, Tatsuta T, von Heijne G, Kim H. Dislocation by the m-AAA protease increases the threshold hydrophobicity for retention of transmembrane helices in the inner membrane of yeast mitochondria. The Journal of Biological Chemistry. 288: 4792-8. PMID 23283966 DOI: 10.1074/jbc.M112.430892 |
0.5 |
|
| 2012 |
Lee H, Min J, von Heijne G, Kim H. Glycosylatable GFP as a compartment-specific membrane topology reporter. Biochemical and Biophysical Research Communications. 427: 780-4. PMID 23047006 DOI: 10.1016/j.bbrc.2012.09.138 |
0.495 |
|
| 2012 |
Ismail N, Hedman R, Schiller N, von Heijne G. A biphasic pulling force acts on transmembrane helices during translocon-mediated membrane integration. Nature Structural & Molecular Biology. 19: 1018-22. PMID 23001004 DOI: 10.1038/nsmb.2376 |
0.533 |
|
| 2012 |
Toddo S, Söderström B, Palombo I, von Heijne G, Nørholm MH, Daley DO. Application of split-green fluorescent protein for topology mapping membrane proteins in Escherichia coli. Protein Science : a Publication of the Protein Society. 21: 1571-6. PMID 22825803 DOI: 10.1002/pro.2131 |
0.51 |
|
| 2012 |
Lloris-Garcerá P, Bianchi F, Slusky JS, Seppälä S, Daley DO, von Heijne G. Antiparallel dimers of the small multidrug resistance protein EmrE are more stable than parallel dimers. The Journal of Biological Chemistry. 287: 26052-9. PMID 22700980 DOI: 10.1074/jbc.M112.357590 |
0.773 |
|
| 2012 |
Galian C, Björkholm P, Bulleid N, von Heijne G. Efficient glycosylphosphatidylinositol (GPI) modification of membrane proteins requires a C-terminal anchoring signal of marginal hydrophobicity. The Journal of Biological Chemistry. 287: 16399-409. PMID 22431723 DOI: 10.1074/jbc.M112.350009 |
0.478 |
|
| 2012 |
Ojemalm K, Halling KK, Nilsson I, von Heijne G. Orientational preferences of neighboring helices can drive ER insertion of a marginally hydrophobic transmembrane helix. Molecular Cell. 45: 529-40. PMID 22281052 DOI: 10.1016/j.molcel.2011.12.024 |
0.585 |
|
| 2012 |
Contreras FX, Ernst AM, Haberkant P, Björkholm P, Lindahl E, Gönen B, Tischer C, Elofsson A, von Heijne G, Thiele C, Pepperkok R, Wieland F, Brügger B. Molecular recognition of a single sphingolipid species by a protein's transmembrane domain. Nature. 481: 525-9. PMID 22230960 DOI: 10.1038/Nature10742 |
0.715 |
|
| 2012 |
Nørholm MH, Light S, Virkki MT, Elofsson A, von Heijne G, Daley DO. Manipulating the genetic code for membrane protein production: what have we learnt so far? Biochimica Et Biophysica Acta. 1818: 1091-6. PMID 21884679 DOI: 10.1016/J.Bbamem.2011.08.018 |
0.665 |
|
| 2011 |
von Heijne G. Introduction to theme "membrane protein folding and insertion". Annual Review of Biochemistry. 80: 157-60. PMID 21675916 DOI: 10.1146/annurev-biochem-111910-091345 |
0.436 |
|
| 2011 |
Nørholm MH, Shulga YV, Aoki S, Epand RM, von Heijne G. Flanking residues help determine whether a hydrophobic segment adopts a monotopic or bitopic topology in the endoplasmic reticulum membrane. The Journal of Biological Chemistry. 286: 25284-90. PMID 21606504 DOI: 10.1074/jbc.M111.244616 |
0.538 |
|
| 2011 |
Öjemalm K, Higuchi T, Jiang Y, Langel Ü, Nilsson I, White SH, Suga H, von Heijne G. Apolar surface area determines the efficiency of translocon-mediated membrane-protein integration into the endoplasmic reticulum. Proceedings of the National Academy of Sciences of the United States of America. 108: E359-64. PMID 21606334 DOI: 10.1073/Pnas.1100120108 |
0.48 |
|
| 2011 |
von Heijne G. Membrane proteins: from bench to bits. Biochemical Society Transactions. 39: 747-50. PMID 21599644 DOI: 10.1042/BST0390747 |
0.605 |
|
| 2011 |
Osterberg M, Calado Botelho S, von Heijne G, Kim H. Charged flanking residues control the efficiency of membrane insertion of the first transmembrane segment in yeast mitochondrial Mgm1p. Febs Letters. 585: 1238-42. PMID 21457713 DOI: 10.1016/j.febslet.2011.03.056 |
0.472 |
|
| 2011 |
Botelho SC, Osterberg M, Reichert AS, Yamano K, Björkholm P, Endo T, von Heijne G, Kim H. TIM23-mediated insertion of transmembrane α-helices into the mitochondrial inner membrane. The Embo Journal. 30: 1003-11. PMID 21326212 DOI: 10.1038/Emboj.2011.29 |
0.501 |
|
| 2011 |
Nørholm MH, Cunningham F, Deber CM, von Heijne G. Converting a marginally hydrophobic soluble protein into a membrane protein. Journal of Molecular Biology. 407: 171-9. PMID 21262233 DOI: 10.1016/J.Jmb.2011.01.035 |
0.531 |
|
| 2010 |
Seppälä S, Slusky JS, Lloris-Garcerá P, Rapp M, von Heijne G. Control of membrane protein topology by a single C-terminal residue. Science (New York, N.Y.). 328: 1698-700. PMID 20508091 DOI: 10.1126/Science.1188950 |
0.803 |
|
| 2010 |
Fagerberg L, Jonasson K, von Heijne G, Uhlén M, Berglund L. Prediction of the human membrane proteome. Proteomics. 10: 1141-9. PMID 20175080 DOI: 10.1002/pmic.200900258 |
0.507 |
|
| 2010 |
Kauko A, Hedin LE, Thebaud E, Cristobal S, Elofsson A, von Heijne G. Repositioning of transmembrane alpha-helices during membrane protein folding. Journal of Molecular Biology. 397: 190-201. PMID 20109468 DOI: 10.1016/J.Jmb.2010.01.042 |
0.74 |
|
| 2010 |
Daniels R, Mellroth P, Bernsel A, Neiers F, Normark S, von Heijne G, Henriques-Normark B. Disulfide bond formation and cysteine exclusion in gram-positive bacteria. The Journal of Biological Chemistry. 285: 3300-9. PMID 19940132 DOI: 10.1074/Jbc.M109.081398 |
0.357 |
|
| 2010 |
Hedin LE, Ojemalm K, Bernsel A, Hennerdal A, Illergård K, Enquist K, Kauko A, Cristobal S, von Heijne G, Lerch-Bader M, Nilsson I, Elofsson A. Membrane insertion of marginally hydrophobic transmembrane helices depends on sequence context. Journal of Molecular Biology. 396: 221-9. PMID 19931281 DOI: 10.1016/J.Jmb.2009.11.036 |
0.754 |
|
| 2009 |
Hessa T, Reithinger JH, von Heijne G, Kim H. Analysis of transmembrane helix integration in the endoplasmic reticulum in S. cerevisiae. Journal of Molecular Biology. 386: 1222-8. PMID 19452628 DOI: 10.1016/j.jmb.2009.01.027 |
0.498 |
|
| 2009 |
Enquist K, Fransson M, Boekel C, Bengtsson I, Geiger K, Lang L, Pettersson A, Johansson S, von Heijne G, Nilsson I. Membrane-integration characteristics of two ABC transporters, CFTR and P-glycoprotein. Journal of Molecular Biology. 387: 1153-64. PMID 19236881 DOI: 10.1016/j.jmb.2009.02.035 |
0.496 |
|
| 2008 |
Lundin C, Kim H, Nilsson I, White SH, von Heijne G. Molecular code for protein insertion in the endoplasmic reticulum membrane is similar for N(in)-C(out) and N(out)-C(in) transmembrane helices. Proceedings of the National Academy of Sciences of the United States of America. 105: 15702-7. PMID 18840693 DOI: 10.1073/Pnas.0804842105 |
0.4 |
|
| 2008 |
von Heijne G, Rees D. Membranes: reading between the lines. Current Opinion in Structural Biology. 18: 403-5. PMID 18634876 DOI: 10.1016/J.Sbi.2008.06.003 |
0.501 |
|
| 2008 |
Cassel M, Seppälä S, von Heijne G. Confronting fusion protein-based membrane protein topology mapping with reality: the Escherichia coli ClcA H+/Cl- exchange transporter. Journal of Molecular Biology. 381: 860-6. PMID 18590742 DOI: 10.1016/j.jmb.2008.06.039 |
0.471 |
|
| 2008 |
White SH, von Heijne G. How translocons select transmembrane helices. Annual Review of Biophysics. 37: 23-42. PMID 18573071 DOI: 10.1146/Annurev.Biophys.37.032807.125904 |
0.579 |
|
| 2008 |
Bernsel A, Viklund H, Falk J, Lindahl E, von Heijne G, Elofsson A. Prediction of membrane-protein topology from first principles. Proceedings of the National Academy of Sciences of the United States of America. 105: 7177-81. PMID 18477697 DOI: 10.1073/Pnas.0711151105 |
0.718 |
|
| 2008 |
Drew D, Newstead S, Sonoda Y, Kim H, von Heijne G, Iwata S. GFP-based optimization scheme for the overexpression and purification of eukaryotic membrane proteins in Saccharomyces cerevisiae. Nature Protocols. 3: 784-98. PMID 18451787 DOI: 10.1038/Nprot.2008.44 |
0.526 |
|
| 2008 |
Lerch-Bader M, Lundin C, Kim H, Nilsson I, von Heijne G. Contribution of positively charged flanking residues to the insertion of transmembrane helices into the endoplasmic reticulum. Proceedings of the National Academy of Sciences of the United States of America. 105: 4127-32. PMID 18326626 DOI: 10.1073/pnas.0711580105 |
0.477 |
|
| 2008 |
Casadio R, Fariselli P, Martelli PL, Pierleoni A, Rossi I, Von Heijne G. The state of the art of membrane protein structure prediction: From sequence to 3D structure Modern Genome Annotation: the Biosapiens Network. 309-326. DOI: 10.1007/978-3-211-75123-7_15 |
0.443 |
|
| 2007 |
Hessa T, Meindl-Beinker NM, Bernsel A, Kim H, Sato Y, Lerch-Bader M, Nilsson I, White SH, von Heijne G. Molecular code for transmembrane-helix recognition by the Sec61 translocon. Nature. 450: 1026-30. PMID 18075582 DOI: 10.1038/Nature06387 |
0.512 |
|
| 2007 |
Xie K, Hessa T, Seppälä S, Rapp M, von Heijne G, Dalbey RE. Features of transmembrane segments that promote the lateral release from the translocase into the lipid phase. Biochemistry. 46: 15153-61. PMID 18052199 DOI: 10.1021/Bi701398Y |
0.559 |
|
| 2007 |
Granseth E, Seppälä S, Rapp M, Daley DO, Von Heijne G. Membrane protein structural biology--how far can the bugs take us? Molecular Membrane Biology. 24: 329-32. PMID 17710636 DOI: 10.1080/09687680701413882 |
0.552 |
|
| 2007 |
Newstead S, Kim H, von Heijne G, Iwata S, Drew D. High-throughput fluorescent-based optimization of eukaryotic membrane protein overexpression and purification in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 104: 13936-41. PMID 17709746 DOI: 10.1073/Pnas.0704546104 |
0.532 |
|
| 2007 |
Lundin C, Johansson S, Johnson AE, Näslund J, von Heijne G, Nilsson I. Stable insertion of Alzheimer Abeta peptide into the ER membrane strongly correlates with its length. Febs Letters. 581: 3809-13. PMID 17659280 DOI: 10.1016/J.Febslet.2007.07.003 |
0.316 |
|
| 2007 |
Stenberg F, von Heijne G, Daley DO. Assembly of the cytochrome bo3 complex. Journal of Molecular Biology. 371: 765-73. PMID 17583738 DOI: 10.1016/j.jmb.2007.05.045 |
0.341 |
|
| 2007 |
Elofsson A, von Heijne G. Membrane protein structure: prediction versus reality. Annual Review of Biochemistry. 76: 125-40. PMID 17579561 DOI: 10.1146/Annurev.Biochem.76.052705.163539 |
0.649 |
|
| 2007 |
von Heijne G. Membrane proteins up for grabs. Nature Biotechnology. 25: 646-7. PMID 17557100 DOI: 10.1038/nbt0607-646 |
0.559 |
|
| 2007 |
von Heijne G. The membrane protein universe: what's out there and why bother? Journal of Internal Medicine. 261: 543-57. PMID 17547710 DOI: 10.1111/j.1365-2796.2007.01792.x |
0.541 |
|
| 2007 |
Emanuelsson O, Brunak S, von Heijne G, Nielsen H. Locating proteins in the cell using TargetP, SignalP and related tools. Nature Protocols. 2: 953-71. PMID 17446895 DOI: 10.1038/Nprot.2007.131 |
0.326 |
|
| 2007 |
Rapp M, Seppälä S, Granseth E, von Heijne G. Emulating membrane protein evolution by rational design. Science (New York, N.Y.). 315: 1282-4. PMID 17255477 DOI: 10.1126/Science.1135406 |
0.58 |
|
| 2006 |
von Heijne G. Membrane-protein topology. Nature Reviews. Molecular Cell Biology. 7: 909-18. PMID 17139331 DOI: 10.1038/nrm2063 |
0.584 |
|
| 2006 |
Meindl-Beinker NM, Lundin C, Nilsson I, White SH, von Heijne G. Asn- and Asp-mediated interactions between transmembrane helices during translocon-mediated membrane protein assembly. Embo Reports. 7: 1111-6. PMID 17008929 DOI: 10.1038/Sj.Embor.7400818 |
0.532 |
|
| 2006 |
Kim H, Melén K, Osterberg M, von Heijne G. A global topology map of the Saccharomyces cerevisiae membrane proteome. Proceedings of the National Academy of Sciences of the United States of America. 103: 11142-7. PMID 16847258 DOI: 10.1073/pnas.0604075103 |
0.53 |
|
| 2006 |
Osterberg M, Kim H, Warringer J, Melén K, Blomberg A, von Heijne G. Phenotypic effects of membrane protein overexpression in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 103: 11148-53. PMID 16847257 DOI: 10.1073/Pnas.0604078103 |
0.464 |
|
| 2006 |
Amico M, Finelli M, Rossi I, Zauli A, Elofsson A, Viklund H, von Heijne G, Jones D, Krogh A, Fariselli P, Luigi Martelli P, Casadio R. PONGO: a web server for multiple predictions of all-alpha transmembrane proteins. Nucleic Acids Research. 34: W169-72. PMID 16844984 DOI: 10.1093/Nar/Gkl208 |
0.591 |
|
| 2006 |
Lundin C, Nordström R, Wagner K, Windpassinger C, Andersson H, von Heijne G, Nilsson I. Membrane topology of the human seipin protein. Febs Letters. 580: 2281-4. PMID 16574104 DOI: 10.1016/j.febslet.2006.03.040 |
0.421 |
|
| 2006 |
Marani P, Wagner S, Baars L, Genevaux P, de Gier JW, Nilsson I, Casadio R, von Heijne G. New Escherichia coli outer membrane proteins identified through prediction and experimental verification. Protein Science : a Publication of the Protein Society. 15: 884-9. PMID 16522795 DOI: 10.1110/ps.051889506 |
0.545 |
|
| 2006 |
Rapp M, Granseth E, Seppälä S, von Heijne G. Identification and evolution of dual-topology membrane proteins. Nature Structural & Molecular Biology. 13: 112-6. PMID 16429150 DOI: 10.1038/Nsmb1057 |
0.571 |
|
| 2006 |
Björklund A, Thorén A, von Heijne G, Elofsson A. The use of phylogenetic profiles for gene predictions revisited Current Genomics. 7: 79-86. DOI: 10.2174/138920206777304650 |
0.456 |
|
| 2005 |
White SH, von Heijne G. Do protein-lipid interactions determine the recognition of transmembrane helices at the ER translocon? Biochemical Society Transactions. 33: 1012-5. PMID 16246034 DOI: 10.1042/Bst20051012 |
0.573 |
|
| 2005 |
Freites JA, Tobias DJ, von Heijne G, White SH. Interface connections of a transmembrane voltage sensor. Proceedings of the National Academy of Sciences of the United States of America. 102: 15059-64. PMID 16217012 DOI: 10.1073/Pnas.0507618102 |
0.338 |
|
| 2005 |
Karamyshev AL, Kelleher DJ, Gilmore R, Johnson AE, von Heijne G, Nilsson I. Mapping the interaction of the STT3 subunit of the oligosaccharyl transferase complex with nascent polypeptide chains. The Journal of Biological Chemistry. 280: 40489-93. PMID 16216884 DOI: 10.1074/Jbc.M509168200 |
0.387 |
|
| 2005 |
Luirink J, von Heijne G, Houben E, de Gier JW. Biogenesis of inner membrane proteins in Escherichia coli. Annual Review of Microbiology. 59: 329-55. PMID 16153172 DOI: 10.1146/annurev.micro.59.030804.121246 |
0.546 |
|
| 2005 |
Granseth E, Daley DO, Rapp M, Melén K, von Heijne G. Experimentally constrained topology models for 51,208 bacterial inner membrane proteins. Journal of Molecular Biology. 352: 489-94. PMID 16120447 DOI: 10.1016/J.Jmb.2005.07.053 |
0.534 |
|
| 2005 |
Stenberg F, Chovanec P, Maslen SL, Robinson CV, Ilag LL, von Heijne G, Daley DO. Protein complexes of the Escherichia coli cell envelope. The Journal of Biological Chemistry. 280: 34409-19. PMID 16079137 DOI: 10.1074/jbc.M506479200 |
0.478 |
|
| 2005 |
Laudon H, Hansson EM, Melén K, Bergman A, Farmery MR, Winblad B, Lendahl U, von Heijne G, Näslund J. A nine-transmembrane domain topology for presenilin 1. The Journal of Biological Chemistry. 280: 35352-60. PMID 16046406 DOI: 10.1074/Jbc.M507217200 |
0.32 |
|
| 2005 |
White SH, von Heijne G. Transmembrane helices before, during, and after insertion. Current Opinion in Structural Biology. 15: 378-86. PMID 16043344 DOI: 10.1016/J.Sbi.2005.07.004 |
0.486 |
|
| 2005 |
Nilsson J, Persson B, von Heijne G. Comparative analysis of amino acid distributions in integral membrane proteins from 107 genomes. Proteins. 60: 606-16. PMID 16028222 DOI: 10.1002/prot.20583 |
0.507 |
|
| 2005 |
Bernsel A, Von Heijne G. Improved membrane protein topology prediction by domain assignments. Protein Science : a Publication of the Protein Society. 14: 1723-8. PMID 15987901 DOI: 10.1110/Ps.051395305 |
0.538 |
|
| 2005 |
Daley DO, Rapp M, Granseth E, Melén K, Drew D, von Heijne G. Global topology analysis of the Escherichia coli inner membrane proteome. Science (New York, N.Y.). 308: 1321-3. PMID 15919996 DOI: 10.1126/Science.1109730 |
0.558 |
|
| 2005 |
Kim H, von Heijne G, Nilsson I. Membrane topology of the STT3 subunit of the oligosaccharyl transferase complex. The Journal of Biological Chemistry. 280: 20261-7. PMID 15781470 DOI: 10.1074/jbc.M412213200 |
0.407 |
|
| 2005 |
Tie JK, Nicchitta C, von Heijne G, Stafford DW. Membrane topology mapping of vitamin K epoxide reductase by in vitro translation/cotranslocation. The Journal of Biological Chemistry. 280: 16410-6. PMID 15716279 DOI: 10.1074/Jbc.M500765200 |
0.417 |
|
| 2005 |
Hessa T, White SH, von Heijne G. Membrane insertion of a potassium-channel voltage sensor. Science (New York, N.Y.). 307: 1427. PMID 15681341 DOI: 10.1126/Science.1109176 |
0.335 |
|
| 2005 |
Hessa T, Kim H, Bihlmaier K, Lundin C, Boekel J, Andersson H, Nilsson I, White SH, von Heijne G. Recognition of transmembrane helices by the endoplasmic reticulum translocon. Nature. 433: 377-81. PMID 15674282 DOI: 10.1038/Nature03216 |
0.563 |
|
| 2005 |
Granseth E, von Heijne G, Elofsson A. A study of the membrane-water interface region of membrane proteins. Journal of Molecular Biology. 346: 377-85. PMID 15663952 DOI: 10.1016/J.Jmb.2004.11.036 |
0.719 |
|
| 2005 |
Monné M, Hessa T, Thissen L, von Heijne G. Competition between neighboring topogenic signals during membrane protein insertion into the ER. The Febs Journal. 272: 28-36. PMID 15634329 DOI: 10.1111/j.1742-4658.2004.04394.x |
0.496 |
|
| 2004 |
White SH, von Heijne G. The machinery of membrane protein assembly. Current Opinion in Structural Biology. 14: 397-404. PMID 15313232 DOI: 10.1016/J.Sbi.2004.07.003 |
0.573 |
|
| 2004 |
Bendtsen JD, Jensen LJ, Blom N, Von Heijne G, Brunak S. Feature-based prediction of non-classical and leaderless protein secretion. Protein Engineering, Design & Selection : Peds. 17: 349-56. PMID 15115854 DOI: 10.1093/Protein/Gzh037 |
0.314 |
|
| 2004 |
Rapp M, Drew D, Daley DO, Nilsson J, Carvalho T, Melén K, De Gier JW, Von Heijne G. Experimentally based topology models for E. coli inner membrane proteins. Protein Science : a Publication of the Protein Society. 13: 937-45. PMID 15044727 DOI: 10.1110/ps.03553804 |
0.473 |
|
| 2004 |
Stefansson A, Armulik A, Nilsson I, Von Heijne G, Johansson S. Determination of N- and C-terminal borders of the transmembrane domain of integrin subunits Journal of Biological Chemistry. 279: 21200-21205. PMID 15016834 DOI: 10.1074/jbc.M400771200 |
0.306 |
|
| 2003 |
Hermansson M, von Heijne G. Inter-helical hydrogen bond formation during membrane protein integration into the ER membrane. Journal of Molecular Biology. 334: 803-9. PMID 14636604 DOI: 10.1016/j.jmb.2003.10.019 |
0.43 |
|
| 2003 |
Andersson H, D'Antona AM, Kendall DA, Von Heijne G, Chin CN. Membrane assembly of the cannabinoid receptor 1: impact of a long N-terminal tail. Molecular Pharmacology. 64: 570-7. PMID 12920192 DOI: 10.1124/Mol.64.3.570 |
0.333 |
|
| 2003 |
Emanuelsson O, Elofsson A, von Heijne G, Cristóbal S. In silico prediction of the peroxisomal proteome in fungi, plants and animals. Journal of Molecular Biology. 330: 443-56. PMID 12823981 DOI: 10.1016/S0022-2836(03)00553-9 |
0.562 |
|
| 2003 |
Kim H, Yan Q, Von Heijne G, Caputo GA, Lennarz WJ. Determination of the membrane topology of Ost4p and its subunit interactions in the oligosaccharyltransferase complex in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 100: 7460-4. PMID 12810948 DOI: 10.1073/Pnas.1332735100 |
0.449 |
|
| 2003 |
Nilsson I, Johnson AE, Von Heijne G. How hydrophobic is alanine? Journal of Biological Chemistry. 278: 29389-29393. PMID 12761228 DOI: 10.1074/Jbc.M212310200 |
0.484 |
|
| 2003 |
Lundin M, Monné M, Widell A, Von Heijne G, Persson MAA. Topology of the membrane-associated hepatitis C virus protein NS4B Journal of Virology. 77: 5428-5438. PMID 12692244 DOI: 10.1128/JVI.77.9.5428-5438.2003 |
0.313 |
|
| 2003 |
Melén K, Krogh A, von Heijne G. Reliability measures for membrane protein topology prediction algorithms. Journal of Molecular Biology. 327: 735-44. PMID 12634065 DOI: 10.1016/S0022-2836(03)00182-7 |
0.427 |
|
| 2003 |
Von Heijne G. Membrane protein assembly in vivo Advances in Protein Chemistry. 63: 1-18. PMID 12629964 DOI: 10.1016/S0065-3233(03)63001-9 |
0.531 |
|
| 2003 |
Hessa T, Monné M, von Heijne G. Stop-transfer efficiency of marginally hydrophobic segments depends on the length of the carboxy-terminal tail Embo Reports. 4: 178-183. PMID 12612608 DOI: 10.1038/sj.embor.embor728 |
0.425 |
|
| 2003 |
Hucke O, Schiltz E, Drews G, Labahn A, Von Heijne G. Sequence analysis reveals new membrane anchor of reaction centre-bound cytochromes possibly related to PufX Febs Letters. 535: 166-170. PMID 12560097 DOI: 10.1016/S0014-5793(02)03899-1 |
0.426 |
|
| 2003 |
Kim H, Melén K, Von Heijne G. Topology models for 37 Saccharomyces cerevisiae membrane proteins based on C-terminal reporter fusions and predictions Journal of Biological Chemistry. 278: 10208-10213. PMID 12524434 DOI: 10.1074/jbc.M300163200 |
0.47 |
|
| 2003 |
Brzezinski P, Von Heijne G, Rydström J. Membrane proteins: Structure, function and assembly Febs Letters. 555: 1. DOI: 10.1016/S0014-5793(03)01147-5 |
0.516 |
|
| 2002 |
Nilsson J, Persson B, Von Heijne G. Prediction of partial membrane protein topologies using a consensus approach Protein Science. 11: 2974-2980. PMID 12441395 DOI: 10.1110/ps.0226702 |
0.519 |
|
| 2002 |
Chin CN, von Heijne G, de Gier JW. Membrane proteins: shaping up. Trends in Biochemical Sciences. 27: 231-4. PMID 12076534 DOI: 10.1016/S0968-0004(02)02082-0 |
0.571 |
|
| 2002 |
von Heijne G. Bioinformatics of membrane proteins Ernst Schering Research Foundation Workshop. 17-27. PMID 12061002 |
0.563 |
|
| 2002 |
Vilar M, Saurí A, Monné M, Marcos JF, Von Heijne G, Pérez-Payá E, Mingarro I. Insertion and topology of a plant viral movement protein in the endoplasmic reticulum membrane Journal of Biological Chemistry. 277: 23447-23452. PMID 11976343 DOI: 10.1074/Jbc.M202935200 |
0.708 |
|
| 2002 |
Nilsson I, Johnson AE, Von Heijne G. Cleavage of a tail-anchored protein by signal peptidase Febs Letters. 516: 106-108. PMID 11959113 DOI: 10.1016/S0014-5793(02)02511-5 |
0.381 |
|
| 2002 |
Drew D, Sjöstrand D, Nilsson J, Urbig T, Chin CN, de Gier JW, von Heijne G. Rapid topology mapping of Escherichia coli inner-membrane proteins by prediction and PhoA/GFP fusion analysis. Proceedings of the National Academy of Sciences of the United States of America. 99: 2690-5. PMID 11867724 DOI: 10.1073/pnas.052018199 |
0.532 |
|
| 2002 |
Hedman M, Deloof H, Von Heijne G, Elofsson A. Improved detection of homologous membrane proteins by inclusion of information from topology predictions. Protein Science : a Publication of the Protein Society. 11: 652-8. PMID 11847287 DOI: 10.1110/Ps.39402 |
0.688 |
|
| 2002 |
Peltier JB, Emanuelsson O, Kalume DE, Ytterberg J, Friso G, Rudella A, Liberles DA, Söderberg L, Roepstorff P, von Heijne G, van Wijk KJ. Central functions of the lumenal and peripheral thylakoid proteome of Arabidopsis determined by experimentation and genome-wide prediction. The Plant Cell. 14: 211-36. PMID 11826309 DOI: 10.1105/Tpc.010304 |
0.344 |
|
| 2002 |
Liberles DA, Thorén A, von Heijne G, Elofsson A. The use of phylogenetic profiles for gene predictions Current Genomics. 3: 131-137. DOI: 10.2174/1389202023350499 |
0.472 |
|
| 2001 |
Hermansson M, Monné M, von Heijne G. Formation of helical hairpins during membrane protein integration into the endoplasmic reticulum membrane. Role of the N and C-terminal flanking regions. Journal of Molecular Biology. 313: 1171-9. PMID 11700072 DOI: 10.1006/jmbi.2001.5108 |
0.497 |
|
| 2001 |
Drew DE, von Heijne G, Nordlund P, de Gier JW. Green fluorescent protein as an indicator to monitor membrane protein overexpression in Escherichia coli. Febs Letters. 507: 220-4. PMID 11684102 DOI: 10.1016/S0014-5793(01)02980-5 |
0.49 |
|
| 2001 |
Nilsson I, Ohvo-Rekilä H, Slotte JP, Johnson AE, Von Heijne G. Inhibition of Protein Translocation across the Endoplasmic Reticulum Membrane by Sterols Journal of Biological Chemistry. 276: 41748-41754. PMID 11535595 DOI: 10.1074/Jbc.M105823200 |
0.467 |
|
| 2001 |
Emanuelsson O, Von Heijne G, Schneider G. Analysis and prediction of mitochondrial targeting pep tides Methods in Cell Biology. 175-187. PMID 11381593 DOI: 10.1016/S0091-679X(01)65011-8 |
0.344 |
|
| 2001 |
Monné M, Von Heijne G. Effects of 'hydrophobic mismatch' on the location of transmembrane helices in the ER membrane Febs Letters. 496: 96-100. PMID 11356190 DOI: 10.1016/S0014-5793(01)02415-2 |
0.471 |
|
| 2001 |
Sääf A, Baars L, Von Heijne G. The Internal Repeats in the Na+/Ca2+ Exchanger-related Escherichia coli Protein YrbG Have Opposite Membrane Topologies Journal of Biological Chemistry. 276: 18905-18907. PMID 11259419 DOI: 10.1074/jbc.M101716200 |
0.43 |
|
| 2001 |
Krogh A, Larsson B, von Heijne G, Sonnhammer EL. Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. Journal of Molecular Biology. 305: 567-80. PMID 11152613 DOI: 10.1006/Jmbi.2000.4315 |
0.496 |
|
| 2000 |
Mingarro I, Nilsson I, Whitley P, von Heijne G. Different conformations of nascent polypeptides during translocation across the ER membrane Bmc Cell Biology [Electronic Resource]. 1: 3. PMID 11178101 DOI: 10.1186/1471-2121-1-3 |
0.684 |
|
| 2000 |
Nilsson J, Persson B, Von Heijne G. Consensus predictions of membrane protein topology Febs Letters. 486: 267-269. PMID 11119716 DOI: 10.1016/S0014-5793(00)02321-8 |
0.46 |
|
| 2000 |
Chin CN, Von Heijne G. Charge pair interactions, in a model transmembrane helix in the ER membrane Journal of Molecular Biology. 303: 1-5. PMID 11021965 DOI: 10.1006/jmbi.2000.4122 |
0.4 |
|
| 2000 |
Killian JA, von Heijne G. How proteins adapt to a membrane-water interface. Trends in Biochemical Sciences. 25: 429-34. PMID 10973056 DOI: 10.1016/S0968-0004(00)01626-1 |
0.517 |
|
| 2000 |
Sääf A, Hermansson M, von Heijne G. Formation of cytoplasmic turns between two closely spaced transmembrane helices during membrane protein integration into the ER membrane. Journal of Molecular Biology. 301: 191-7. PMID 10926501 DOI: 10.1006/jmbi.2000.3933 |
0.579 |
|
| 2000 |
Emanuelsson O, Nielsen H, Brunak S, Von Heijne G. Predicting subcellular localization of proteins based on their N-terminal amino acid sequence Journal of Molecular Biology. 300: 1005-1016. PMID 10891285 DOI: 10.1006/Jmbi.2000.3903 |
0.311 |
|
| 2000 |
Hasler U, Greasley PJ, Von Heijne G, Geering K. Determinants of topogenesis and glycosylation of type II membrane proteins. Analysis of Na,K-ATPase β1 and β3 subunits by glycosylation mapping Journal of Biological Chemistry. 275: 29011-29022. PMID 10887183 |
0.514 |
|
| 2000 |
Nilsson I, Witt S, Kiefer H, Mingarro I, Von Heijne G. Distant downstream sequence determinants can control N-tail translocation during protein insertion into the endoplasmic reticulum membrane Journal of Biological Chemistry. 275: 6207-6213. PMID 10692414 DOI: 10.1074/Jbc.275.9.6207 |
0.692 |
|
| 2000 |
Scotti PA, Urbanus ML, Brunner J, De Gier JWL, Von Heijne G, Van Der Does C, Driessen AJM, Oudega B, Luirink J. YidC, the Escherichia coli homologue of mitochondrial Oxa1p, is a component of the Sec translocase Embo Journal. 19: 542-549. PMID 10675323 DOI: 10.1093/Emboj/19.4.542 |
0.539 |
|
| 2000 |
Von Heijne G. Transport of peptides and proteins through membranes. Editorial overview Current Opinion in Cell Biology. 12: 399. DOI: 10.1016/S0955-0674(00)00107-1 |
0.409 |
|
| 1999 |
Von Heijne G. Recent advances in the understanding of membrane protein assembly and structure Quarterly Reviews of Biophysics. 32: 285-307. PMID 11194567 DOI: 10.1017/S0033583500003541 |
0.516 |
|
| 1999 |
Devoto A, Piffanelli P, Nilsson I, Wallin E, Panstruga R, Von Heijne G, Schulze-Lefert P. Topology, subcellular localization, and sequence diversity of the Mlo family in plants Journal of Biological Chemistry. 274: 34993-35004. PMID 10574976 DOI: 10.1074/jbc.274.49.34993 |
0.394 |
|
| 1999 |
Monné M, Nilsson I, Elofsson A, von Heijne G. Turns in transmembrane helices: determination of the minimal length of a "helical hairpin" and derivation of a fine-grained turn propensity scale. Journal of Molecular Biology. 293: 807-14. PMID 10543969 DOI: 10.1006/Jmbi.1999.3183 |
0.588 |
|
| 1999 |
Monné M, Gafvelin G, Nilsson R, von Heijne G. N-tail translocation in a eukaryotic polytopic membrane protein. Synergy between neighboring transmembrane segments European Journal of Biochemistry. 263: 264-269. PMID 10429212 DOI: 10.1046/j.1432-1327.1999.00498.x |
0.391 |
|
| 1999 |
Braun P, Von Heijne G. The aromatic residues Trp and phe have different effects on the positioning of a transmembrane helix in the microsomal membrane Biochemistry. 38: 9778-9782. PMID 10423258 DOI: 10.1021/bi990923a |
0.481 |
|
| 1999 |
Sääf A, Johansson M, Wallin E, Von Heijne G. Divergent evolution of membrane protein topology: The Escherichia coli RnfA and RnfE homologues Proceedings of the National Academy of Sciences of the United States of America. 96: 8540-8544. PMID 10411911 DOI: 10.1073/pnas.96.15.8540 |
0.584 |
|
| 1999 |
Cristóbal S, Scotti P, Luirink J, Von Heijne G, De Gier JWL. The signal recognition particle-targeting pathway does not necessarily deliver proteins to the Sec-translocase in Escherichia coli Journal of Biological Chemistry. 274: 20068-20070. PMID 10400614 DOI: 10.1074/jbc.274.29.20068 |
0.387 |
|
| 1999 |
Monné M, Hermansson M, von Heijne G. A turn propensity scale for transmembrane helices. Journal of Molecular Biology. 288: 141-5. PMID 10329132 DOI: 10.1006/jmbi.1999.2657 |
0.459 |
|
| 1999 |
Van Geest M, Nilsson I, Von Heijne G, Lolkema JS. Insertion of a bacterial secondary transport protein in the endoplasmic reticulum membrane Journal of Biological Chemistry. 274: 2816-2823. PMID 9915815 DOI: 10.1074/jbc.274.5.2816 |
0.504 |
|
| 1998 |
De Gier JWL, Scotti PA, Sääf A, Valent QA, Kuhn A, Luirink J, Von Heijne G. Differential use of the signal recognition particle translocase targeting pathway for inner membrane protein assembly in Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 95: 14646-14651. PMID 9843943 DOI: 10.1073/pnas.95.25.14646 |
0.48 |
|
| 1998 |
Nilsson I, Von Heijne G. Breaking the camel's back: Proline-induced turns in a model transmembrane helix Journal of Molecular Biology. 284: 1185-1189. PMID 9837736 DOI: 10.1006/jmbi.1998.2219 |
0.58 |
|
| 1998 |
Monné M, Nilsson I, Johansson M, Elmhed N, Von Heijne G. Positively and negatively charged residues have different effects on the position in the membrane of a model transmembrane helix Journal of Molecular Biology. 284: 1177-1183. PMID 9837735 DOI: 10.1006/jmbi.1998.2218 |
0.339 |
|
| 1998 |
Nilsson I, Sääf A, Whitley P, Gafvelin G, Waller C, Von Heijne G. Proline-induced disruption of a transmembrane α-helix in its natural environment Journal of Molecular Biology. 284: 1165-1175. PMID 9837734 DOI: 10.1006/jmbi.1998.2217 |
0.502 |
|
| 1998 |
Ota K, Sakaguchi M, Von Heijne G, Hamasaki N, Mihara K. Forced transmembrane orientation of hydrophilic polypeptide segments in multispanning membrane proteins Molecular Cell. 2: 495-503. PMID 9809071 |
0.522 |
|
| 1998 |
Sääf A, Monné M, De Gier JW, Von Heijne G. Membrane topology of the 60-kDa Oxa1p homologue from Escherichia coli Journal of Biological Chemistry. 273: 30415-30418. PMID 9804807 DOI: 10.1074/jbc.273.46.30415 |
0.568 |
|
| 1998 |
Von Heijne G. Structural aspects of transmembrane α-helices Acta Physiologica Scandinavica, Supplement. 163: 17-19. PMID 9789543 |
0.552 |
|
| 1998 |
Sonnhammer EL, von Heijne G, Krogh A. A hidden Markov model for predicting transmembrane helices in protein sequences. Proceedings / ... International Conference On Intelligent Systems For Molecular Biology ; Ismb. International Conference On Intelligent Systems For Molecular Biology. 6: 175-82. PMID 9783223 |
0.485 |
|
| 1998 |
Seshadri K, Garemyr R, Wallin E, von Heijne G, Elofsson A. Architecture of beta-barrel membrane proteins: analysis of trimeric porins. Protein Science : a Publication of the Protein Society. 7: 2026-32. PMID 9761484 DOI: 10.1002/Pro.5560070919 |
0.686 |
|
| 1998 |
van Klompenburg W, Paetzel M, de Jong JM, Dalbey RE, Demel RA, von Heijne G, de Kruijff B. Phosphatidylethanolamine mediates insertion of the catalytic domain of leader peptidase in membranes. Febs Letters. 431: 75-9. PMID 9684869 DOI: 10.1016/S0014-5793(98)00733-9 |
0.482 |
|
| 1998 |
Wallin E, Von Heijne G. Genome-wide analysis of integral membrane proteins from eubacterial, archaean, and eukaryotic organisms Protein Science. 7: 1029-1038. PMID 9568909 |
0.53 |
|
| 1998 |
Valent QA, Scotti PA, High S, De Gier JWL, Von Heijne G, Lentzen G, Wintermeyer W, Oudega B, Luirink J. The Escherichia coli SRP and SecB targeting pathways converge at the translocon Embo Journal. 17: 2504-2512. PMID 9564033 DOI: 10.1093/emboj/17.9.2504 |
0.51 |
|
| 1998 |
Sääf A, Wallin E, Von Heijne G. Stop-transfer function of pseudo-random amino acid segments during translocation across prokaryotic and eukaryotic membranes European Journal of Biochemistry. 251: 821-829. PMID 9490057 |
0.335 |
|
| 1998 |
Mingarro I, von Heijne G, Whitley P. Membrane-protein engineering. Trends in Biotechnology. 15: 432-7. PMID 9351288 DOI: 10.1016/S0167-7799(97)01101-3 |
0.712 |
|
| 1997 |
Valent QA, de Gier JW, von Heijne G, Kendall DA, ten Hagen-Jongman CM, Oudega B, Luirink J. Nascent membrane and presecretory proteins synthesized in Escherichia coli associate with signal recognition particle and trigger factor. Molecular Microbiology. 25: 53-64. PMID 11902726 DOI: 10.1046/J.1365-2958.1997.4431808.X |
0.412 |
|
| 1997 |
Braun P, Persson B, Kaback HR, Von Heijne G. Alanine insertion scanning mutagenesis of lactose permease transmembrane helices Journal of Biological Chemistry. 272: 29566-29571. PMID 9368019 DOI: 10.1074/jbc.272.47.29566 |
0.483 |
|
| 1997 |
Mingarro I, Elofsson A, von Heijne G. Helix-helix packing in a membrane-like environment. Journal of Molecular Biology. 272: 633-41. PMID 9325117 DOI: 10.1006/Jmbi.1997.1276 |
0.74 |
|
| 1997 |
Van Klompenburg W, Ridder ANJA, Van Raalte ALJ, Killian AJ, Von Heijne G, De Kruijff B. In vitro membrane integration of leader peptidase depends on the Sec machinery and anionic phospholipids and can occur post-translationally Febs Letters. 413: 109-114. PMID 9287126 DOI: 10.1016/S0014-5793(97)00888-0 |
0.504 |
|
| 1997 |
Cserzö M, Wallin E, Simon I, von Heijne G, Elofsson A. Prediction of transmembrane alpha-helices in prokaryotic membrane proteins: the dense alignment surface method. Protein Engineering. 10: 673-6. PMID 9278280 DOI: 10.1093/Protein/10.6.673 |
0.694 |
|
| 1997 |
Van Klompenburg W, Nilsson I, Von Heijne G, De Kruijff B. Anionic phospholipids are determinants of membrane protein topology Embo Journal. 16: 4261-4266. PMID 9250669 DOI: 10.1093/emboj/16.14.4261 |
0.521 |
|
| 1997 |
De Gier JWL, Valent QA, Von Heijne G, Luirink J. The E. coli SRP: Preferences of a targeting factor Febs Letters. 408: 1-4. PMID 9180256 DOI: 10.1016/S0014-5793(97)00402-X |
0.342 |
|
| 1997 |
von Heijne G. Principles of membrane protein assembly and structure. Progress in Biophysics and Molecular Biology. 66: 113-39. PMID 9175426 DOI: 10.1016/s0079-6107(97)85627-1 |
0.539 |
|
| 1997 |
Wallin E, Tsukihara T, Yoshikawa S, von Heijne G, Elofsson A. Architecture of helix bundle membrane proteins: an analysis of cytochrome c oxidase from bovine mitochondria. Protein Science : a Publication of the Protein Society. 6: 808-15. PMID 9098890 DOI: 10.1002/Pro.5560060407 |
0.69 |
|
| 1997 |
Gafvelin G, Sakaguchi M, Andersson H, von Heijne G. Topological rules for membrane protein assembly in eukaryotic cells. The Journal of Biological Chemistry. 272: 6119-27. PMID 9045622 DOI: 10.1074/jbc.272.10.6119 |
0.548 |
|
| 1997 |
Andersson H, Nilsson I, von Heijne G. Calnexin can interact with N-linked glycans located close to the endoplasmic reticulum membrane. Febs Letters. 397: 321-4. PMID 8955372 DOI: 10.1016/S0014-5793(96)01207-0 |
0.508 |
|
| 1997 |
Mingarro I, Whitley P, Lemmon MA, von Heijne G. Ala-insertion scanning mutagenesis of the glycophorin A transmembrane helix: a rapid way to map helix-helix interactions in integral membrane proteins. Protein Science : a Publication of the Protein Society. 5: 1339-41. PMID 8819166 DOI: 10.1002/Pro.5560050712 |
0.695 |
|
| 1996 |
De Gier JWL, Mansournia P, Valent QA, Phillips GJ, Luirink J, Von Heijne G. Assembly of a cytoplasmic membrane protein in Escherichia coli is dependent on the signal recognition particle Febs Letters. 399: 307-309. PMID 8985168 DOI: 10.1016/S0014-5793(96)01354-3 |
0.484 |
|
| 1996 |
Glick BS, Von Heijne G. Saccharomyces cerevisiae mitochondria lack a bacterial-type Sec machinery Protein Science. 5: 2651-2652. PMID 8976575 |
0.33 |
|
| 1996 |
Johansson M, von Heijne G. Membrane topology of Kch, a putative K+ channel from Escherichia coli. The Journal of Biological Chemistry. 271: 25912-5. PMID 8824224 DOI: 10.1074/jbc.271.42.25912 |
0.394 |
|
| 1996 |
Whitley P, Sääf A, Gafvelin G, Johansson M, Wallin E, von Heijne G. Membrane protein anchors and polytopic determinants. Biochemical Society Transactions. 23: 965-7. PMID 8654875 DOI: 10.1042/bst0230965 |
0.56 |
|
| 1996 |
Whitley P, Grahn E, Kutay U, Rapoport TA, von Heijne G. A 12-residue-long polyleucine tail is sufficient to anchor synaptobrevin to the endoplasmic reticulum membrane. The Journal of Biological Chemistry. 271: 7583-6. PMID 8631791 DOI: 10.1074/Jbc.271.13.7583 |
0.451 |
|
| 1996 |
Wallin E, von Heijne G. Properties of N-terminal tails in G-protein coupled receptors: a statistical study. Protein Engineering. 8: 693-8. PMID 8577697 DOI: 10.1093/protein/8.7.693 |
0.359 |
|
| 1996 |
Whitley P, Gafvelin G, von Heijne G. SecA-independent translocation of the periplasmic N-terminal tail of an Escherichia coli inner membrane protein. Position-specific effects on translocation of positively charged residues and construction of a protein with a C-terminal translocation signal. The Journal of Biological Chemistry. 270: 29831-5. PMID 8530378 DOI: 10.1074/jbc.270.50.29831 |
0.393 |
|
| 1995 |
Dalbey RE, Kuhn A, von Heijne G. Directionality in protein translocation across membranes: the N-tail phenomenon. Trends in Cell Biology. 5: 380-3. PMID 14732054 DOI: 10.1016/S0962-8924(00)89079-0 |
0.372 |
|
| 1995 |
Hirsch S, Muckel E, Heemeyer F, von Heijne G, Soll J. A receptor component of the chloroplast protein translocation machinery. Science (New York, N.Y.). 266: 1989-92. PMID 7801125 DOI: 10.1126/Science.7801125 |
0.491 |
|
| 1995 |
Sääf A, Andersson H, Gafvelin G, von Heijne G. SecA-dependence of the translocation of a large periplasmic loop in the Escherichia coli MalF inner membrane protein is a function of sequence context. Molecular Membrane Biology. 12: 209-15. PMID 7795711 DOI: 10.3109/09687689509027509 |
0.497 |
|
| 1994 |
Andersson H, von Heijne G. Positively charged residues influence the degree of SecA dependence in protein translocation across the E. coli inner membrane. Febs Letters. 347: 169-72. PMID 8033997 DOI: 10.1016/0014-5793(94)00530-3 |
0.505 |
|
| 1994 |
Whitley P, Zander T, Ehrmann M, Haardt M, Bremer E, von Heijne G. Sec-independent translocation of a 100-residue periplasmic N-terminal tail in the E. coli inner membrane protein proW. The Embo Journal. 13: 4653-4661. DOI: 10.1002/j.1460-2075.1994.tb06788.x |
0.462 |
|
| 1994 |
Andersson H, von Heijne G. Membrane protein topology: effects of delta mu H+ on the translocation of charged residues explain the ‘positive inside’ rule. The Embo Journal. 13: 2267-2272. DOI: 10.1002/j.1460-2075.1994.tb06508.x |
0.42 |
|
| 1993 |
Nilsson IM, Gafvelin G, von Heijne G. Different sec-requirements for signal peptide cleavage and protein translocation in a model E. coli protein. Febs Letters. 318: 7-10. PMID 8436228 DOI: 10.1016/0014-5793(93)81316-R |
0.328 |
|
| 1993 |
Whitley P, von Heijne G. The DsbA-DsbB system affects the formation of disulfide bonds in periplasmic but not in intramembraneous protein domains. Febs Letters. 332: 49-51. PMID 8405447 DOI: 10.1016/0014-5793(93)80481-9 |
0.411 |
|
| 1993 |
Whitley P, Nilsson L, von Heijne G. Three-dimensional model for the membrane domain of Escherichia coli leader peptidase based on disulfide mapping. Biochemistry. 32: 8534-9. PMID 8357800 DOI: 10.1021/Bi00084A020 |
0.438 |
|
| 1993 |
Sipos L, von Heijne G. Predicting the topology of eukaryotic membrane proteins. European Journal of Biochemistry. 213: 1333-40. PMID 8099327 DOI: 10.1111/j.1432-1033.1993.tb17885.x |
0.461 |
|
| 1993 |
Andersson H, von Heijne G. Sec dependent and sec independent assembly of E. coli inner membrane proteins: the topological rules depend on chain length. The Embo Journal. 12: 683-691. DOI: 10.1002/j.1460-2075.1993.tb05702.x |
0.428 |
|
| 1992 |
Gavel Y, von Heijne G. The distribution of charged amino acids in mitochondrial inner-membrane proteins suggests different modes of membrane integration for nuclearly and mitochondrially encoded proteins. European Journal of Biochemistry. 205: 1207-15. PMID 1577002 DOI: 10.1111/j.1432-1033.1992.tb16892.x |
0.467 |
|
| 1992 |
Nilsson I, von Heijne G. A signal peptide with a proline next to the cleavage site inhibits leader peptidase when present in a sec-independent protein. Febs Letters. 299: 243-6. PMID 1544500 DOI: 10.1016/0014-5793(92)80124-Y |
0.344 |
|
| 1992 |
Cramer WA, Engelman DM, Von Heijne G, Rees DC. Forces involved in the assembly and stabilization of membrane proteins Faseb Journal. 6: 3397-3402. PMID 1464373 DOI: 10.1096/Fasebj.6.15.1464373 |
0.589 |
|
| 1991 |
von Heijne G, Manoil C. Membrane proteins: from sequence to structure. Protein Engineering. 4: 109-12. PMID 2075184 DOI: 10.1093/Protein/4.2.109 |
0.57 |
|
| 1991 |
Gavel Y, Steppuhn J, Herrmann R, von Heijne G. The 'positive-inside rule' applies to thylakoid membrane proteins. Febs Letters. 282: 41-6. PMID 2026263 DOI: 10.1016/0014-5793(91)80440-E |
0.555 |
|
| 1991 |
Andersson H, von Heijne G. A 30-residue-long "export initiation domain" adjacent to the signal sequence is critical for protein translocation across the inner membrane of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 88: 9751-4. PMID 1946398 DOI: 10.1073/pnas.88.21.9751 |
0.373 |
|
| 1988 |
von Heijne G, Wickner W, Dalbey RE. The cytoplasmic domain of Escherichia coli leader peptidase is a "translocation poison" sequence. Proceedings of the National Academy of Sciences of the United States of America. 85: 3363-6. PMID 3285342 DOI: 10.1073/Pnas.85.10.3363 |
0.626 |
|
| 1988 |
von Heijne G, Gavel Y. Topogenic signals in integral membrane proteins. European Journal of Biochemistry. 174: 671-8. PMID 3134198 DOI: 10.1111/j.1432-1033.1988.tb14150.x |
0.572 |
|
| 1987 |
von Heijne G, Segrest JP. The leader peptides from bacteriorhodopsin and halorhodopsin are potential membrane-spanning amphipathic helices. Febs Letters. 213: 238-40. PMID 3556582 DOI: 10.1016/0014-5793(87)81497-7 |
0.46 |
|
| 1986 |
Flinta C, Persson B, Jörnvall H, von Heijne G. Sequence determinants of cytosolic N-terminal protein processing. European Journal of Biochemistry. 154: 193-6. PMID 3080313 DOI: 10.1111/j.1432-1033.1986.tb09378.x |
0.3 |
|
| 1983 |
Flinta C, von Heijne G, Johansson J. Helical sidedness and the distribution of polar residues in trans-membrane helices. Journal of Molecular Biology. 168: 193-6. PMID 6876176 DOI: 10.1016/S0022-2836(83)80330-1 |
0.309 |
|
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