Year |
Citation |
Score |
2024 |
Azam S, Armijo KS, Weindel CG, Chapman MJ, Devigne A, Nakagawa S, Hirose T, Carpenter S, Watson RO, Patrick KL. The early macrophage response to pathogens requires dynamic regulation of the nuclear paraspeckle. Proceedings of the National Academy of Sciences of the United States of America. 121: e2312587121. PMID 38381785 DOI: 10.1073/pnas.2312587121 |
0.408 |
|
2023 |
Scott HM, Smith MH, Coleman AK, Apostalo SL, Wagner AR, Watson RO, Patrick KL. Serine arginine-rich splicing factor (SRSF7) cooperates with the histone methyltransferase KMT5a to promote the type I interferon response via transcriptional activation of IRF7. Biorxiv : the Preprint Server For Biology. PMID 37503164 DOI: 10.1101/2023.05.09.540055 |
0.784 |
|
2023 |
Ellzey LM, Patrick KL, Watson RO. Mitochondrial reactive oxygen species: double agents in Mycobacterium tuberculosis infection. Current Opinion in Immunology. 84: 102366. PMID 37453340 DOI: 10.1016/j.coi.2023.102366 |
0.67 |
|
2023 |
Weindel CG, Ellzey LM, Martinez EL, Watson RO, Patrick KL. Gasdermins gone wild: new roles for GSDMs in regulating cellular homeostasis. Trends in Cell Biology. PMID 37062616 DOI: 10.1016/j.tcb.2023.02.007 |
0.611 |
|
2022 |
Wagner AR, Weindel CG, West KO, Scott HM, Watson RO, Patrick KL. SRSF6 balances mitochondrial-driven innate immune outcomes through alternative splicing of BAX. Elife. 11. PMID 36409059 DOI: 10.7554/eLife.82244 |
0.788 |
|
2022 |
Weindel CG, Martinez EL, Zhao X, Mabry CJ, Bell SL, Vail KJ, Coleman AK, VanPortfliet JJ, Zhao B, Wagner AR, Azam S, Scott HM, Li P, West AP, Karpac J, ... Patrick KL, et al. Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis. Cell. PMID 35907404 DOI: 10.1016/j.cell.2022.06.038 |
0.727 |
|
2022 |
Wells KM, He K, Pandey A, Cabello A, Zhang D, Yang J, Gomez G, Liu Y, Chang H, Li X, Zhang H, Feng X, da Costa LF, Metz R, Johnson CD, ... ... Patrick KL, et al. activates the host RIDD pathway to subvert BLOS1-directed immune defense. Elife. 11. PMID 35587649 DOI: 10.7554/eLife.73625 |
0.389 |
|
2021 |
Vail KJ, da Silveira BP, Bell SL, Cohen ND, Bordin AI, Patrick KL, Watson RO. The opportunistic intracellular bacterial pathogen Rhodococcusequi elicits type I interferon by engaging cytosolic DNA sensing in macrophages. Plos Pathogens. 17: e1009888. PMID 34473814 DOI: 10.1371/journal.ppat.1009888 |
0.631 |
|
2021 |
Wagner AR, Scott HM, West KO, Vail KJ, Fitzsimons TC, Coleman AK, Carter KE, Watson RO, Patrick KL. Global Transcriptomics Uncovers Distinct Contributions From Splicing Regulatory Proteins to the Macrophage Innate Immune Response. Frontiers in Immunology. 12: 656885. PMID 34305890 DOI: 10.3389/fimmu.2021.656885 |
0.79 |
|
2021 |
Bell SL, Lopez KL, Cox JS, Patrick KL, Watson RO. Galectin-8 Senses Phagosomal Damage and Recruits Selective Autophagy Adapter TAX1BP1 To Control Infection in Macrophages. Mbio. e0187120. PMID 34225486 DOI: 10.1128/mBio.01871-20 |
0.651 |
|
2021 |
Ding S, Yang J, Feng X, Pandey A, Barhoumi R, Zhang D, Bell SL, Liu Y, da Costa LF, Rice-Ficht A, Watson RO, Patrick KL, Qin QM, Ficht TA, de Figueiredo P. Interactions between fungal hyaluronic acid and host CD44 promote internalization by recruiting host autophagy proteins to forming phagosomes. Iscience. 24: 102192. PMID 33718841 DOI: 10.1016/j.isci.2021.102192 |
0.628 |
|
2021 |
Patrick KL, Watson RO. Mitochondria: powering the innate immune response to infection. Infection and Immunity. PMID 33558322 DOI: 10.1128/IAI.00687-20 |
0.698 |
|
2020 |
Hoffpauir CT, Bell SL, West KO, Jing T, Wagner AR, Torres-Odio S, Cox JS, West AP, Li P, Patrick KL, Watson RO. TRIM14 Is a Key Regulator of the Type I IFN Response during Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 32404352 DOI: 10.4049/Jimmunol.1901511 |
0.804 |
|
2020 |
Weindel CG, Bell SL, Vail KJ, West KO, Patrick KL, Watson RO. LRRK2 maintains mitochondrial homeostasis and regulates innate immune responses to . Elife. 9. PMID 32057291 DOI: 10.7554/Elife.51071 |
0.726 |
|
2020 |
Antoine M, Patrick KL, Soret J, Duc P, Rage F, Cacciottolo R, Nissen KE, Cauchi RJ, Krogan NJ, Guthrie C, Gachet Y, Bordonné R. Splicing Defects of the Profilin Gene Alter Actin Dynamics in an S. pombe SMN Mutant. Iscience. 23: 100809. PMID 31927482 DOI: 10.1016/J.Isci.2019.100809 |
0.723 |
|
2020 |
Weindel CG, Bell SL, Vail KJ, West KO, Patrick KL, Watson RO. Author response: LRRK2 maintains mitochondrial homeostasis and regulates innate immune responses to Mycobacterium tuberculosis Elife. DOI: 10.7554/Elife.51071.Sa2 |
0.677 |
|
2019 |
West KO, Scott HM, Torres-Odio S, West AP, Patrick KL, Watson RO. The Splicing Factor hnRNP M Is a Critical Regulator of Innate Immune Gene Expression in Macrophages. Cell Reports. 29: 1594-1609.e5. PMID 31693898 DOI: 10.1016/J.Celrep.2019.09.078 |
0.808 |
|
2019 |
Patrick KL, Bell SL, Weindel CG, Watson RO. Exploring the "Multiple-Hit Hypothesis" of Neurodegenerative Disease: Bacterial Infection Comes Up to Bat. Frontiers in Cellular and Infection Microbiology. 9: 138. PMID 31192157 DOI: 10.3389/Fcimb.2019.00138 |
0.672 |
|
2018 |
Patrick KL, Wojcechowskyj JA, Bell SL, Riba MN, Jing T, Talmage S, Xu P, Cabello AL, Xu J, Shales M, Jimenez-Morales D, Ficht TA, de Figueiredo P, Samuel JE, Li P, et al. Quantitative Yeast Genetic Interaction Profiling of Bacterial Effector Proteins Uncovers a Role for the Human Retromer in Salmonella Infection. Cell Systems. PMID 30077634 DOI: 10.1016/J.Cels.2018.06.010 |
0.669 |
|
2017 |
Nissen KE, Homer CM, Ryan CJ, Shales M, Krogan NJ, Patrick KL, Guthrie C. The histone variant H2A.Z promotes splicing of weak introns. Genes & Development. 31: 688-701. PMID 28446597 DOI: 10.1101/Gad.295287.116 |
0.738 |
|
2016 |
Patrick KL, Bell SL, Watson RO. For better or worse: Cytosolic DNA sensing during intracellular bacterial infection induces potent innate immune responses. Journal of Molecular Biology. PMID 27139640 DOI: 10.1016/J.Jmb.2016.04.030 |
0.675 |
|
2015 |
Patrick KL, Ryan CJ, Xu J, Lipp JJ, Nissen KE, Roguev A, Shales M, Krogan NJ, Guthrie C. Genetic interaction mapping reveals a role for the SWI/SNF nucleosome remodeler in spliceosome activation in fission yeast. Plos Genetics. 11: e1005074. PMID 25825871 DOI: 10.1371/Journal.Pgen.1005074 |
0.758 |
|
2012 |
Ryan CJ, Roguev A, Patrick K, Xu J, Jahari H, Tong Z, Beltrao P, Shales M, Qu H, Collins SR, Kliegman JI, Jiang L, Kuo D, Tosti E, Kim HS, et al. Hierarchical modularity and the evolution of genetic interactomes across species. Molecular Cell. 46: 691-704. PMID 22681890 DOI: 10.1016/J.Molcel.2012.05.028 |
0.544 |
|
2009 |
Patrick KL, Shi H, Kolev NG, Ersfeld K, Tschudi C, Ullu E. Distinct and overlapping roles for two Dicer-like proteins in the RNA interference pathways of the ancient eukaryote Trypanosoma brucei. Proceedings of the National Academy of Sciences of the United States of America. 106: 17933-8. PMID 19815526 DOI: 10.1073/Pnas.0907766106 |
0.677 |
|
2008 |
Patrick KL, Luz PM, Ruan JP, Shi H, Ullu E, Tschudi C. Genomic rearrangements and transcriptional analysis of the spliced leader-associated retrotransposon in RNA interference-deficient Trypanosoma brucei. Molecular Microbiology. 67: 435-47. PMID 18067542 DOI: 10.1111/J.1365-2958.2007.06057.X |
0.674 |
|
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