| Year |
Citation |
Score |
| 2023 |
Alemán-Ruiz C, Wang W, Dingledine R, Varvel NH. Pharmacological inhibition of the inflammatory receptor CCR2 relieves the early deleterious consequences of status epilepticus. Scientific Reports. 13: 5651. PMID 37024553 DOI: 10.1038/s41598-023-32752-9 |
0.742 |
|
| 2023 |
Harris LD, Regan MC, Myers SJ, Nocilla KA, Akins NS, Tahirovic YA, Wilson LJ, Dingledine R, Furukawa H, Traynelis SF, Liotta DC. Novel GluN2B-Selective NMDA Receptor Negative Allosteric Modulator Possesses Intrinsic Analgesic Properties and Enhances Analgesia of Morphine in a Rodent Tail Flick Pain Model. Acs Chemical Neuroscience. PMID 36779874 DOI: 10.1021/acschemneuro.2c00779 |
0.729 |
|
| 2023 |
Zaczek R, Traynelis SF, Dingledine R, Koszalka GW, Laskowitz DT. Phase 1 Clinical Results for NP10679, a pH-sensitive GluN2B-selective N-methyl-d-aspartate Receptor Inhibitor. Clinical Pharmacology in Drug Development. PMID 36642931 DOI: 10.1002/cpdd.1217 |
0.514 |
|
| 2020 |
Jiang C, Caskurlu A, Ganesh T, Dingledine R. Inhibition of the prostaglandin EP2 receptor prevents long-term cognitive impairment in a model of systemic inflammation. Brain, Behavior, & Immunity - Health. 8: 100132. PMID 34589882 DOI: 10.1016/j.bbih.2020.100132 |
0.781 |
|
| 2020 |
Jiang C, Amaradhi R, Ganesh T, Dingledine R. An Agonist Dependent Allosteric Antagonist of Prostaglandin EP2 Receptors. Acs Chemical Neuroscience. PMID 32324375 DOI: 10.1021/Acschemneuro.0C00078 |
0.814 |
|
| 2020 |
Rojas A, Wang J, Glover A, Dingledine R. Urethane attenuates early neuropathology of diisopropylfluorophosphate-induced status epilepticus in rats. Neurobiology of Disease. 104863. PMID 32283202 DOI: 10.1016/J.Nbd.2020.104863 |
0.598 |
|
| 2020 |
Amaradhi R, Banik A, Mohammed S, Patro V, Rojas A, Wang W, Motati DR, Dingledine R, Ganesh T. Potent, selective, water soluble, brain-permeable EP2 receptor antagonist for use in central nervous system disease models. Journal of Medicinal Chemistry. PMID 31904232 DOI: 10.1021/Acs.Jmedchem.9B01218 |
0.811 |
|
| 2020 |
Jiang C, Amaradhi R, Ganesh T, Dingledine R. A Noncompetitive and Selective Prostaglandin EP2 Antagonist with Anti‐inflammatory Property The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.00241 |
0.78 |
|
| 2019 |
Khan N, Schoenike B, Basu T, Grabenstatter H, Rodriguez G, Sindic C, Johnson M, Wallace E, Maganti R, Dingledine R, Roopra A. A systems approach identifies Enhancer of Zeste Homolog 2 (EZH2) as a protective factor in epilepsy. Plos One. 14: e0226733. PMID 31891591 DOI: 10.1371/Journal.Pone.0226733 |
0.679 |
|
| 2019 |
Rojas A, Banik A, Chen D, Flood K, Ganesh T, Dingledine R. A novel microglia cell line expressing the human EP2 receptor. Acs Chemical Neuroscience. PMID 31469538 DOI: 10.1021/Acschemneuro.9B00311 |
0.808 |
|
| 2019 |
Manji Z, Rojas A, Wang W, Dingledine R, Varvel NH, Ganesh N. 5xFAD Mice Display Sex-Dependent Inflammatory Gene Induction During the Prodromal Stage of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 31322556 DOI: 10.3233/Jad-180678 |
0.766 |
|
| 2019 |
Rojas A, Ganesh T, Wang W, Wang J, Dingledine R. A rat model of organophosphate-induced status epilepticus and the beneficial effects of EP2 receptor inhibition. Neurobiology of Disease. PMID 30818067 DOI: 10.1016/J.Nbd.2019.02.010 |
0.769 |
|
| 2019 |
Jiang J, Yu Y, Kinjo E, Du Y, Nguyen H, Dingledine R. Suppressing pro-inflammatory prostaglandin signaling attenuates excitotoxicity-associated neuronal inflammation and injury. Neuropharmacology. PMID 30763657 DOI: 10.1016/J.Neuropharm.2019.02.011 |
0.718 |
|
| 2019 |
Taraschenko O, Fox HS, Pittock SJ, Zekeridou A, Gafurova M, Eldridge E, Liu J, Dravid SM, Dingledine R. A mouse model of seizures in anti-N-methyl-d-aspartate receptor encephalitis. Epilepsia. PMID 30740690 DOI: 10.1111/Epi.14662 |
0.791 |
|
| 2018 |
Rojas A, Chen D, Ganesh T, Varvel NH, Dingledine R. The COX-2/prostanoid signaling cascades in seizure disorders. Expert Opinion On Therapeutic Targets. PMID 30484341 DOI: 10.1080/14728222.2019.1554056 |
0.818 |
|
| 2018 |
Ganesh T, Banik A, Dingledine R, Wang W, Amaradhi R. Peripherally restricted, highly potent, selective, aqueous-soluble EP2 antagonist with anti-inflammatory properties. Molecular Pharmaceutics. PMID 30398879 DOI: 10.1021/Acs.Molpharmaceut.8B00764 |
0.801 |
|
| 2018 |
Rojas A, Wang W, Glover A, Manji Z, Fu Y, Dingledine R. Beneficial Outcome of Urethane Treatment Following Status Epilepticus in a Rat Organophosphorus Toxicity Model. Eneuro. 5. PMID 29766039 DOI: 10.1523/ENEURO.0070-18.2018 |
0.792 |
|
| 2018 |
Jiang J, Van TM, Ganesh T, Dingledine R. Discovery of 2-Piperidinyl Phenyl Benzamides and Trisubstituted Pyrimidines as Positive Allosteric Modulators of the Prostaglandin Receptor EP2. Acs Chemical Neuroscience. PMID 29292987 DOI: 10.1021/Acschemneuro.7B00486 |
0.804 |
|
| 2017 |
Klein P, Dingledine R, Aronica E, Bernard C, Blümcke I, Boison D, Brodie MJ, Brooks-Kayal AR, Engel J, Forcelli PA, Hirsch LJ, Kaminski RM, Klitgaard H, Kobow K, Lowenstein DH, et al. Commonalities in epileptogenic processes from different acute brain insults: Do they translate? Epilepsia. PMID 29247482 DOI: 10.1111/Epi.13965 |
0.349 |
|
| 2017 |
Aronica E, Bauer S, Bozzi Y, Caleo M, Dingledine R, Gorter JA, Henshall DC, Kaufer D, Koh S, Löscher W, Louboutin JP, Mishto M, Norwood BA, Palma E, Poulter MO, et al. Neuroinflammatory targets and treatments for epilepsy validated in experimental models. Epilepsia. 58: 27-38. PMID 28675563 DOI: 10.1111/Epi.13783 |
0.32 |
|
| 2017 |
Dingledine R, Coulter DA, Fritsch B, Gorter JA, Lelutiu N, McNamara J, Nadler JV, Pitkänen A, Rogawski MA, Skene P, Sloviter RS, Wang Y, Wadman WJ, Wasterlain C, Roopra A. Transcriptional profile of hippocampal dentate granule cells in four rat epilepsy models. Scientific Data. 4: 170061. PMID 28485718 DOI: 10.1038/Sdata.2017.61 |
0.728 |
|
| 2017 |
Rojas A, Ganesh T, Walker A, Dingledine R. Ethylatropine bromide as a peripherally-restricted muscarinic antagonist. Acs Chemical Neuroscience. PMID 28044440 DOI: 10.1021/Acschemneuro.6B00334 |
0.747 |
|
| 2016 |
Varvel NH, Neher JJ, Bosch A, Wang W, Ransohoff RM, Miller RJ, Dingledine R. Infiltrating monocytes promote brain inflammation and exacerbate neuronal damage after status epilepticus. Proceedings of the National Academy of Sciences of the United States of America. PMID 27601660 DOI: 10.1073/Pnas.1604263113 |
0.744 |
|
| 2016 |
Rojas A, Ganesh T, Manji Z, O'neill T, Dingledine R. Inhibition of the prostaglandin E2 receptor EP2 prevents status epilepticus-induced deficits in the novel object recognition task in rats. Neuropharmacology. PMID 27477533 DOI: 10.1016/J.Neuropharm.2016.07.028 |
0.751 |
|
| 2016 |
Dingledine R, Hassel B. A New Approach for Epilepsy. Cerebrum : the Dana Forum On Brain Science. 2016. PMID 27408679 |
0.627 |
|
| 2016 |
Galanopoulou AS, Wong M, Binder D, Hartman AL, Powell EM, Roopra A, Staba R, Vezzani A, Fureman B, Dingledine R. 2014 Epilepsy Benchmarks Area II: Prevent Epilepsy and Its Progression. Epilepsy Currents / American Epilepsy Society. 16: 187-91. PMID 27330451 DOI: 10.5698/1535-7511-16.3.187 |
0.641 |
|
| 2015 |
Brown JH, Catterall WA, Conn PJ, Cull-Candy SG, Dingledine R, Harden TK, Insel PA, Milligan G, Traynelis SF. The First 50 Years of Molecular Pharmacology. Molecular Pharmacology. 88: 139-40. PMID 25943115 DOI: 10.1124/mol.115.099564 |
0.616 |
|
| 2015 |
Fu Y, Yang MS, Jiang J, Ganesh T, Joe E, Dingledine R. EP2 Receptor Signaling Regulates Microglia Death. Molecular Pharmacology. 88: 161-70. PMID 25715797 DOI: 10.1124/Mol.115.098202 |
0.777 |
|
| 2015 |
Hassel B, Elsais A, Frøland AS, Taubøll E, Gjerstad L, Quan Y, Dingledine R, Rise F. Uptake and metabolism of fructose by rat neocortical cells in vivo and by isolated nerve terminals in vitro. Journal of Neurochemistry. 133: 572-81. PMID 25708447 DOI: 10.1111/Jnc.13079 |
0.779 |
|
| 2015 |
Rojas A, Ganesh T, Lelutiu N, Gueorguieva P, Dingledine R. Inhibition of the prostaglandin EP2 receptor is neuroprotective and accelerates functional recovery in a rat model of organophosphorus induced status epilepticus. Neuropharmacology. 93: 15-27. PMID 25656476 DOI: 10.1016/J.Neuropharm.2015.01.017 |
0.77 |
|
| 2015 |
Jiang J, Yang MS, Quan Y, Gueorguieva P, Ganesh T, Dingledine R. Therapeutic window for cyclooxygenase-2 related anti-inflammatory therapy after status epilepticus. Neurobiology of Disease. 76: 126-36. PMID 25600211 DOI: 10.1016/J.Nbd.2014.12.032 |
0.803 |
|
| 2015 |
Varvel NH, Jiang J, Dingledine R. Candidate drug targets for prevention or modification of epilepsy. Annual Review of Pharmacology and Toxicology. 55: 229-47. PMID 25196047 DOI: 10.1146/Annurev-Pharmtox-010814-124607 |
0.792 |
|
| 2014 |
Dingledine R, Varvel NH, Dudek FE. When and how do seizures kill neurons, and is cell death relevant to epileptogenesis? Advances in Experimental Medicine and Biology. 813: 109-22. PMID 25012371 DOI: 10.1007/978-94-017-8914-1_9 |
0.737 |
|
| 2014 |
Rojas A, Gueorguieva P, Lelutiu N, Quan Y, Shaw R, Dingledine R. The prostaglandin EP1 receptor potentiates kainate receptor activation via a protein kinase C pathway and exacerbates status epilepticus. Neurobiology of Disease. 70: 74-89. PMID 24952362 DOI: 10.1016/J.Nbd.2014.06.004 |
0.766 |
|
| 2014 |
Ganesh T, Jiang J, Dingledine R. Development of second generation EP2 antagonists with high selectivity. European Journal of Medicinal Chemistry. 82: 521-35. PMID 24937185 DOI: 10.1016/J.Ejmech.2014.05.076 |
0.788 |
|
| 2014 |
Ganesh T, Jiang J, Yang MS, Dingledine R. Lead optimization studies of cinnamic amide EP2 antagonists. Journal of Medicinal Chemistry. 57: 4173-84. PMID 24773616 DOI: 10.1021/Jm5000672 |
0.799 |
|
| 2014 |
Rojas A, Jiang J, Ganesh T, Yang MS, Lelutiu N, Gueorguieva P, Dingledine R. Cyclooxygenase-2 in epilepsy. Epilepsia. 55: 17-25. PMID 24446952 DOI: 10.1111/Epi.12461 |
0.79 |
|
| 2013 |
Ganesh T, Jiang J, Shashidharamurthy R, Dingledine R. Discovery and characterization of carbamothioylacrylamides as EP2 selective antagonists. Acs Medicinal Chemistry Letters. 4: 616-621. PMID 23914286 DOI: 10.1021/Ml400112H |
0.761 |
|
| 2013 |
Jiang J, Dingledine R. Prostaglandin receptor EP2 in the crosshairs of anti-inflammation, anti-cancer, and neuroprotection. Trends in Pharmacological Sciences. 34: 413-23. PMID 23796953 DOI: 10.1016/J.Tips.2013.05.003 |
0.661 |
|
| 2013 |
Quan Y, Jiang J, Dingledine R. EP2 receptor signaling pathways regulate classical activation of microglia. The Journal of Biological Chemistry. 288: 9293-302. PMID 23404506 DOI: 10.1074/Jbc.M113.455816 |
0.758 |
|
| 2013 |
Jiang J, Quan Y, Ganesh T, Pouliot WA, Dudek FE, Dingledine R. Inhibition of the prostaglandin receptor EP2 following status epilepticus reduces delayed mortality and brain inflammation. Proceedings of the National Academy of Sciences of the United States of America. 110: 3591-6. PMID 23401547 DOI: 10.1073/Pnas.1218498110 |
0.817 |
|
| 2013 |
Rojas A, Dingledine R. Ionotropic glutamate receptors: regulation by G-protein-coupled receptors. Molecular Pharmacology. 83: 746-52. PMID 23348498 DOI: 10.1124/Mol.112.083352 |
0.608 |
|
| 2013 |
Cox B, Han JS, Dingledine R. Avram Goldstein: the founder of molecular pharmacology. Molecular Pharmacology. 83: 720-2. PMID 23329728 DOI: 10.1124/Mol.112.084640 |
0.442 |
|
| 2013 |
Jiang J, Dingledine R. Role of prostaglandin receptor EP2 in the regulations of cancer cell proliferation, invasion, and inflammation. The Journal of Pharmacology and Experimental Therapeutics. 344: 360-7. PMID 23192657 DOI: 10.1124/Jpet.112.200444 |
0.65 |
|
| 2013 |
Rojas A, Wetherington J, Shaw R, Serrano G, Swanger S, Dingledine R. Activation of group I metabotropic glutamate receptors potentiates heteromeric kainate receptors. Molecular Pharmacology. 83: 106-21. PMID 23066089 DOI: 10.1124/Mol.112.081802 |
0.815 |
|
| 2012 |
Roopra A, Dingledine R, Hsieh J. Epigenetics and epilepsy. Epilepsia. 53: 2-10. PMID 23216574 DOI: 10.1111/Epi.12030 |
0.678 |
|
| 2012 |
Levin JR, Serrano G, Dingledine R. Reduction in delayed mortality and subtle improvement in retrograde memory performance in pilocarpine-treated mice with conditional neuronal deletion of cyclooxygenase-2 gene. Epilepsia. 53: 1411-20. PMID 22780884 DOI: 10.1111/J.1528-1167.2012.03584.X |
0.53 |
|
| 2012 |
Jiang J, Ganesh T, Du Y, Quan Y, Serrano G, Qui M, Speigel I, Rojas A, Lelutiu N, Dingledine R. Small molecule antagonist reveals seizure-induced mediation of neuronal injury by prostaglandin E2 receptor subtype EP2. Proceedings of the National Academy of Sciences of the United States of America. 109: 3149-54. PMID 22323596 DOI: 10.1073/Pnas.1120195109 |
0.826 |
|
| 2012 |
Dingledine RJ, Bennett JA. Structure and Function of Ligand-Gated Channels The Cortical Neuron. DOI: 10.1093/acprof:oso/9780195083309.003.0005 |
0.394 |
|
| 2012 |
Min J, Du Y, Bondesen B, Revennaugh B, Eimon P, Dingledine R. Use of transgenic zebrafish in a phenotypic screen for angiogenesis inhibitors Chemical Genomics. 225-231. DOI: 10.1017/CBO9781139021500.021 |
0.751 |
|
| 2011 |
Serrano GE, Lelutiu N, Rojas A, Cochi S, Shaw R, Makinson CD, Wang D, FitzGerald GA, Dingledine R. Ablation of cyclooxygenase-2 in forebrain neurons is neuroprotective and dampens brain inflammation after status epilepticus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 14850-60. PMID 22016518 DOI: 10.1523/Jneurosci.3922-11.2011 |
0.693 |
|
| 2011 |
Friedman A, Dingledine R. Molecular cascades that mediate the influence of inflammation on epilepsy. Epilepsia. 52: 33-9. PMID 21542844 DOI: 10.1111/J.1528-1167.2011.03034.X |
0.342 |
|
| 2011 |
Mott DD, Dingledine R. Unraveling the role of zinc in memory. Proceedings of the National Academy of Sciences of the United States of America. 108: 3103-4. PMID 21321213 DOI: 10.1073/pnas.1100323108 |
0.527 |
|
| 2011 |
Laezza F, Dingledine R. Induction and expression rules of synaptic plasticity in hippocampal interneurons. Neuropharmacology. 60: 720-9. PMID 21195098 DOI: 10.1016/J.Neuropharm.2010.12.016 |
0.669 |
|
| 2010 |
Lau AG, Irier HA, Gu J, Tian D, Ku L, Liu G, Xia M, Fritsch B, Zheng JQ, Dingledine R, Xu B, Lu B, Feng Y. Distinct 3'UTRs differentially regulate activity-dependent translation of brain-derived neurotrophic factor (BDNF). Proceedings of the National Academy of Sciences of the United States of America. 107: 15945-50. PMID 20733072 DOI: 10.1073/Pnas.1002929107 |
0.796 |
|
| 2010 |
Traynelis SF, Wollmuth LP, McBain CJ, Menniti FS, Vance KM, Ogden KK, Hansen KB, Yuan H, Myers SJ, Dingledine R. Glutamate receptor ion channels: structure, regulation, and function. Pharmacological Reviews. 62: 405-96. PMID 20716669 DOI: 10.1124/Pr.109.002451 |
0.808 |
|
| 2010 |
Benveniste M, Wilhelm J, Dingledine RJ, Mott DD. Subunit-dependent modulation of kainate receptors by muscarinic acetylcholine receptors. Brain Research. 1352: 61-9. PMID 20655886 DOI: 10.1016/J.Brainres.2010.07.029 |
0.752 |
|
| 2010 |
Hassel B, Taubøll E, Shaw R, Gjerstad L, Dingledine R. Region-specific changes in gene expression in rat brain after chronic treatment with levetiracetam or phenytoin. Epilepsia. 51: 1714-20. PMID 20345932 DOI: 10.1111/j.1528-1167.2010.02545.x |
0.76 |
|
| 2010 |
Greene JG, Dingledine R, Greenamyre JT. Neuron-selective changes in RNA transcripts related to energy metabolism in toxic models of parkinsonism in rodents. Neurobiology of Disease. 38: 476-81. PMID 20307667 DOI: 10.1016/j.nbd.2010.03.014 |
0.699 |
|
| 2010 |
Jiang J, Ganesh T, Du Y, Thepchatri P, Rojas A, Lewis I, Kurtkaya S, Li L, Qui M, Serrano G, Shaw R, Sun A, Dingledine R. Neuroprotection by selective allosteric potentiators of the EP2 prostaglandin receptor. Proceedings of the National Academy of Sciences of the United States of America. 107: 2307-12. PMID 20080612 DOI: 10.1073/Pnas.0909310107 |
0.816 |
|
| 2010 |
Mott DD, Rojas A, Fisher JL, Dingledine RJ, Benveniste M. Subunit-specific desensitization of heteromeric kainate receptors. The Journal of Physiology. 588: 683-700. PMID 20026616 DOI: 10.1113/Jphysiol.2009.185207 |
0.762 |
|
| 2010 |
Dingledine R. Glutamatergic mechanisms related to epilepsy: Ionotropic receptors Epilepsia. 51: 15. DOI: 10.1111/j.1528-1167.2010.02801.x |
0.445 |
|
| 2009 |
Thepchatri P, Min J, Ganesh T, Du Y, Lewis I, Kurtkaya S, Prussia A, Li L, Sneed B, Plemper RK, Fu H, Liotta DC, Snyder JP, Dingledine R, Sun A. Cancer and virus leads by HTS, chemical design and SEA data mining. Current Topics in Medicinal Chemistry. 9: 1159-71. PMID 19807668 DOI: 10.2174/156802609789753581 |
0.605 |
|
| 2009 |
Irier HA, Quan Y, Yoo J, Dingledine R. Control of glutamate receptor 2 (GluR2) translational initiation by its alternative 3' untranslated regions. Molecular Pharmacology. 76: 1145-9. PMID 19794129 DOI: 10.1124/Mol.109.060343 |
0.785 |
|
| 2009 |
Mosley CA, Myers SJ, Murray EE, Santangelo R, Tahirovic YA, Kurtkaya N, Mullasseril P, Yuan H, Lyuboslavsky P, Le P, Wilson LJ, Yepes M, Dingledine R, Traynelis SF, Liotta DC. Synthesis, structural activity-relationships, and biological evaluation of novel amide-based allosteric binding site antagonists in NR1A/NR2B N-methyl-D-aspartate receptors. Bioorganic & Medicinal Chemistry. 17: 6463-80. PMID 19648014 DOI: 10.1016/J.Bmc.2009.05.085 |
0.816 |
|
| 2009 |
Irier HA, Shaw R, Lau A, Feng Y, Dingledine R. Translational regulation of GluR2 mRNAs in rat hippocampus by alternative 3' untranslated regions. Journal of Neurochemistry. 109: 584-94. PMID 19222700 DOI: 10.1111/J.1471-4159.2009.05992.X |
0.797 |
|
| 2009 |
Greene JG, Borges K, Dingledine R. Quantitative transcriptional neuroanatomy of the rat hippocampus: evidence for wide-ranging, pathway-specific heterogeneity among three principal cell layers. Hippocampus. 19: 253-64. PMID 18830999 DOI: 10.1002/Hipo.20502 |
0.698 |
|
| 2008 |
Tahirovic YA, Geballe M, Gruszecka-Kowalik E, Myers SJ, Lyuboslavsky P, Le P, French A, Irier H, Choi WB, Easterling K, Yuan H, Wilson LJ, Kotloski R, McNamara JO, Dingledine R, et al. Enantiomeric propanolamines as selective N-methyl-D-aspartate 2B receptor antagonists. Journal of Medicinal Chemistry. 51: 5506-21. PMID 18800760 DOI: 10.1021/Jm8002153 |
0.804 |
|
| 2008 |
Ganesh T, Min J, Thepchatri P, Du Y, Li L, Lewis I, Wilson L, Fu H, Chiosis G, Dingledine R, Liotta D, Snyder JP, Sun A. Discovery of aminoquinolines as a new class of potent inhibitors of heat shock protein 90 (Hsp90): Synthesis, biology, and molecular modeling. Bioorganic & Medicinal Chemistry. 16: 6903-10. PMID 18571929 DOI: 10.1016/J.Bmc.2008.05.047 |
0.59 |
|
| 2008 |
Borges K, Gearing M, Rittling S, Sorensen ES, Kotloski R, Denhardt DT, Dingledine R. Characterization of osteopontin expression and function after status epilepticus. Epilepsia. 49: 1675-85. PMID 18522644 DOI: 10.1111/J.1528-1167.2008.01613.X |
0.558 |
|
| 2008 |
Wetherington J, Serrano G, Dingledine R. Astrocytes in the epileptic brain. Neuron. 58: 168-78. PMID 18439402 DOI: 10.1016/J.Neuron.2008.04.002 |
0.759 |
|
| 2008 |
Mott DD, Benveniste M, Dingledine RJ. pH-dependent inhibition of kainate receptors by zinc. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1659-71. PMID 18272686 DOI: 10.1523/Jneurosci.3567-07.2008 |
0.737 |
|
| 2008 |
Greene JG, Greenamyre JT, Dingledine R. Sequential and concerted gene expression changes in a chronic in vitro model of parkinsonism. Neuroscience. 152: 198-207. PMID 18191903 DOI: 10.1016/j.neuroscience.2007.11.029 |
0.702 |
|
| 2007 |
Bough KJ, Paquet M, Paré JF, Hassel B, Smith Y, Hall RA, Dingledine R. Evidence against enhanced glutamate transport in the anticonvulsant mechanism of the ketogenic diet. Epilepsy Research. 74: 232-6. PMID 17416486 DOI: 10.1016/j.eplepsyres.2007.03.002 |
0.801 |
|
| 2007 |
Borges K, Shaw R, Dingledine R. Gene expression changes after seizure preconditioning in the three major hippocampal cell layers. Neurobiology of Disease. 26: 66-77. PMID 17239605 DOI: 10.1016/J.Nbd.2006.12.001 |
0.578 |
|
| 2006 |
Bough KJ, Wetherington J, Hassel B, Pare JF, Gawryluk JW, Greene JG, Shaw R, Smith Y, Geiger JD, Dingledine RJ. Mitochondrial biogenesis in the anticonvulsant mechanism of the ketogenic diet. Annals of Neurology. 60: 223-35. PMID 16807920 DOI: 10.1002/Ana.20899 |
0.777 |
|
| 2006 |
Borges K, McDermott D, Irier H, Smith Y, Dingledine R. Degeneration and proliferation of astrocytes in the mouse dentate gyrus after pilocarpine-induced status epilepticus. Experimental Neurology. 201: 416-27. PMID 16793040 DOI: 10.1016/J.Expneurol.2006.04.031 |
0.789 |
|
| 2005 |
Greene JG, Dingledine R, Greenamyre JT. Gene expression profiling of rat midbrain dopamine neurons: implications for selective vulnerability in parkinsonism. Neurobiology of Disease. 18: 19-31. PMID 15649693 DOI: 10.1016/j.nbd.2004.10.003 |
0.694 |
|
| 2005 |
Benveniste M, Dingledine R. Limiting stroke-induced damage by targeting an acid channel. The New England Journal of Medicine. 352: 85-6. PMID 15635119 DOI: 10.1056/Nejmcibr045010 |
0.599 |
|
| 2004 |
Liu Y, Ciliax BJ, Borges K, Dasigi V, Ram A, Navathe SB, Dingledine R. Comparison of two schemes for automatic keyword extraction from MEDLINE for functional gene clustering. Proceedings / Ieee Computational Systems Bioinformatics Conference, Csb. Ieee Computational Systems Bioinformatics Conference. 394-404. PMID 16448032 DOI: 10.1109/CSB.2004.1332452 |
0.437 |
|
| 2004 |
Doherty JJ, Alagarsamy S, Bough KJ, Conn PJ, Dingledine R, Mott DD. Metabotropic glutamate receptors modulate feedback inhibition in a developmentally regulated manner in rat dentate gyrus. The Journal of Physiology. 561: 395-401. PMID 15513941 DOI: 10.1113/jphysiol.2004.074930 |
0.795 |
|
| 2004 |
Laezza F, Dingledine R. Voltage-controlled plasticity at GluR2-deficient synapses onto hippocampal interneurons. Journal of Neurophysiology. 92: 3575-81. PMID 15331617 DOI: 10.1152/Jn.00425.2004 |
0.689 |
|
| 2004 |
Borges K, McDermott DL, Dingledine R. Reciprocal changes of CD44 and GAP-43 expression in the dentate gyrus inner molecular layer after status epilepticus in mice. Experimental Neurology. 188: 1-10. PMID 15191797 DOI: 10.1016/J.Expneurol.2004.03.019 |
0.558 |
|
| 2004 |
Bough KJ, Mott DD, Dingledine RJ. Medial perforant path inhibition mediated by mGluR7 is reduced after status epilepticus. Journal of Neurophysiology. 92: 1549-57. PMID 15152022 DOI: 10.1152/jn.00315.2004 |
0.806 |
|
| 2004 |
Myers SJ, Huang Y, Genetta T, Dingledine R. Inhibition of glutamate receptor 2 translation by a polymorphic repeat sequence in the 5'-untranslated leaders. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3489-99. PMID 15071096 DOI: 10.1523/Jneurosci.4127-03.2004 |
0.782 |
|
| 2003 |
Mott DD, Dingledine R. Interneuron Diversity series: Interneuron research--challenges and strategies. Trends in Neurosciences. 26: 484-8. PMID 12948659 DOI: 10.1016/S0166-2236(03)00200-5 |
0.493 |
|
| 2003 |
Borges K, Myers SJ, Zhang S, Dingledine R. Activity of the rat GluR4 promoter in transfected cortical neurons and glia. Journal of Neurochemistry. 86: 1162-73. PMID 12911624 DOI: 10.1046/J.1471-4159.2003.01926.X |
0.767 |
|
| 2003 |
Borges K, Gearing M, McDermott DL, Smith AB, Almonte AG, Wainer BH, Dingledine R. Neuronal and glial pathological changes during epileptogenesis in the mouse pilocarpine model. Experimental Neurology. 182: 21-34. PMID 12821374 DOI: 10.1016/S0014-4886(03)00086-4 |
0.791 |
|
| 2003 |
Mott DD, Washburn MS, Zhang S, Dingledine RJ. Subunit-dependent modulation of kainate receptors by extracellular protons and polyamines. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 1179-88. PMID 12598606 |
0.561 |
|
| 2003 |
Doherty J, Dingledine R. Functional interactions between cannabinoid and metabotropic glutamate receptors in the central nervous system. Current Opinion in Pharmacology. 3: 46-53. PMID 12550741 DOI: 10.1016/S1471-4892(02)00014-0 |
0.642 |
|
| 2002 |
Doherty J, Dingledine R. The roles of metabotropic glutamate receptors in seizures and epilepsy. Current Drug Targets. Cns and Neurological Disorders. 1: 251-60. PMID 12769618 DOI: 10.2174/1568007023339355 |
0.634 |
|
| 2002 |
Maccaferri G, Dingledine R. Complex effects of CNQX on CA1 interneurons of the developing rat hippocampus. Neuropharmacology. 43: 523-9. PMID 12367599 DOI: 10.1016/S0028-3908(02)00161-2 |
0.768 |
|
| 2002 |
Huang Y, Doherty JJ, Dingledine R. Altered histone acetylation at glutamate receptor 2 and brain-derived neurotrophic factor genes is an early event triggered by status epilepticus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 8422-8. PMID 12351716 DOI: 10.1523/Jneurosci.22-19-08422.2002 |
0.762 |
|
| 2002 |
Maccaferri G, Dingledine R. Control of feedforward dendritic inhibition by NMDA receptor-dependent spike timing in hippocampal interneurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 5462-72. PMID 12097498 DOI: 10.1523/Jneurosci.22-13-05462.2002 |
0.772 |
|
| 2001 |
Roopra A, Huang Y, Dingledine R. Neurological disease: listening to gene silencers. Molecular Interventions. 1: 219-28. PMID 14993344 |
0.625 |
|
| 2001 |
Jacobs MP, Fischbach GD, Davis MR, Dichter MA, Dingledine R, Lowenstein DH, Morrell MJ, Noebels JL, Rogawski MA, Spencer SS, Theodore WH. Future directions for epilepsy research. Neurology. 57: 1536-42. PMID 11706087 DOI: 10.1212/Wnl.57.9.1536 |
0.302 |
|
| 2001 |
Borges K, Dingledine R. Functional organization of the GluR1 glutamate receptor promoter. The Journal of Biological Chemistry. 276: 25929-38. PMID 11340067 DOI: 10.1074/Jbc.M009105200 |
0.612 |
|
| 2001 |
Doherty J, Dingledine R. Reduced excitatory drive onto interneurons in the dentate gyrus after status epilepticus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 2048-57. PMID 11245688 DOI: 10.1523/Jneurosci.21-06-02048.2001 |
0.639 |
|
| 2000 |
Dingledine R, Conn PJ. Peripheral glutamate receptors: molecular biology and role in taste sensation. The Journal of Nutrition. 130: 1039S-42S. PMID 10736377 DOI: 10.1093/Jn/130.4.1039S |
0.426 |
|
| 2000 |
Dingledine R, Doherty J. Genomics and epilepsy research in the new millenium Acta Neurologica Scandinavica, Supplement. 102: 9-10. DOI: 10.1034/J.1600-0404.2000.00202-4.X |
0.545 |
|
| 1999 |
Huang Y, Myers SJ, Dingledine R. Transcriptional repression by REST: recruitment of Sin3A and histone deacetylase to neuronal genes. Nature Neuroscience. 2: 867-72. PMID 10491605 DOI: 10.1038/13165 |
0.61 |
|
| 1999 |
Laezza F, Doherty JJ, Dingledine R. Long-term depression in hippocampal interneurons: joint requirement for pre- and postsynaptic events. Science (New York, N.Y.). 285: 1411-4. PMID 10464102 DOI: 10.1126/Science.285.5432.1411 |
0.767 |
|
| 1999 |
Myers SJ, Dingledine R, Borges K. Genetic regulation of glutamate receptor ion channels. Annual Review of Pharmacology and Toxicology. 39: 221-41. PMID 10331083 DOI: 10.1146/Annurev.Pharmtox.39.1.221 |
0.662 |
|
| 1999 |
Dingledine R, Borges K, Bowie D, Traynelis SF. The glutamate receptor ion channels. Pharmacological Reviews. 51: 7-61. PMID 10049997 |
0.652 |
|
| 1998 |
Mott DD, Doherty JJ, Zhang S, Washburn MS, Fendley MJ, Lyuboslavsky P, Traynelis SF, Dingledine R. Phenylethanolamines inhibit NMDA receptors by enhancing proton inhibition. Nature Neuroscience. 1: 659-67. PMID 10196581 DOI: 10.1038/3661 |
0.784 |
|
| 1998 |
Borges K, Dingledine R. AMPA receptors: molecular and functional diversity. Progress in Brain Research. 116: 153-70. PMID 9932376 DOI: 10.1016/S0079-6123(08)60436-7 |
0.652 |
|
| 1998 |
Myers SJ, Peters J, Huang Y, Comer MB, Barthel F, Dingledine R. Transcriptional regulation of the GluR2 gene: neural-specific expression, multiple promoters, and regulatory elements. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 6723-39. PMID 9712644 DOI: 10.1523/Jneurosci.18-17-06723.1998 |
0.647 |
|
| 1998 |
Doherty J, Dingledine R. Differential regulation of synaptic inputs to dentate hilar border interneurons by metabotropic glutamate receptors. Journal of Neurophysiology. 79: 2903-10. PMID 9636096 DOI: 10.1152/Jn.1998.79.6.2903 |
0.629 |
|
| 1998 |
Myers SJ, Peters J, Huang Y, Comer MB, Barthel F, Dingledine R. Transcriptional Regulation of the GluR2 Gene: Neural-Specific Expression, Multiple Promoters, and Regulatory Elements The Journal of Neuroscience. 18: 6723-6739. DOI: 10.1523/JNEUROSCI.18-17-06723.1998 |
0.547 |
|
| 1997 |
Washburn MS, Numberger M, Zhang S, Dingledine R. Differential dependence on GluR2 expression of three characteristic features of AMPA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 9393-406. PMID 9390995 DOI: 10.1523/Jneurosci.17-24-09393.1997 |
0.438 |
|
| 1997 |
Doherty J, Dingledine R. Regulation of excitatory input to inhibitory interneurons of the dentate gyrus during hypoxia. Journal of Neurophysiology. 77: 393-404. PMID 9120580 DOI: 10.1152/Jn.1997.77.1.393 |
0.652 |
|
| 1996 |
Washburn MS, Dingledine R. Block of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors by polyamines and polyamine toxins. The Journal of Pharmacology and Experimental Therapeutics. 278: 669-78. PMID 8768718 |
0.336 |
|
| 1995 |
Bennett JA, Dingledine R. Topology profile for a glutamate receptor: three transmembrane domains and a channel-lining reentrant membrane loop. Neuron. 14: 373-84. PMID 7857646 DOI: 10.1016/0896-6273(95)90293-7 |
0.499 |
|
| 1995 |
Kneisler TB, Dingledine R. Spontaneous and synaptic input from granule cells and the perforant path to dentate basket cells in the rat hippocampus. Hippocampus. 5: 151-64. PMID 7550611 DOI: 10.1002/hipo.450050302 |
0.799 |
|
| 1995 |
Kneisler TB, Dingledine R. Synaptic input from CA3 pyramidal cells to dentate basket cells in rat hippocampus. The Journal of Physiology. 487: 125-46. PMID 7473243 DOI: 10.1113/jphysiol.1995.sp020866 |
0.781 |
|
| 1993 |
Kawajiri S, Dingledine R. Multiple structural determinants of voltage-dependent magnesium block in recombinant NMDA receptors. Neuropharmacology. 32: 1203-11. PMID 8107974 DOI: 10.1016/0028-3908(93)90014-T |
0.363 |
|
| 1993 |
McBain CJ, Dingledine R. Heterogeneity of synaptic glutamate receptors on CA3 stratum radiatum interneurones of rat hippocampus. The Journal of Physiology. 462: 373-92. PMID 8101227 DOI: 10.1113/jphysiol.1993.sp019560 |
0.715 |
|
| 1992 |
Curras MC, Dingledine R. Selectivity of amino acid transmitters acting at N-methyl-D-aspartate and amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors. Molecular Pharmacology. 41: 520-6. PMID 1372086 |
0.795 |
|
| 1992 |
McBain CJ, Eaton JV, Brown T, Dingledine R. CNQX increases spontaneous inhibitory input to CA3 pyramidal neurones in neonatal rat hippocampal slices. Brain Research. 592: 255-60. PMID 1360312 DOI: 10.1016/0006-8993(92)91683-6 |
0.736 |
|
| 1992 |
Dingledine R, Hume RI, Heinemann SF. Structural determinants of barium permeation and rectification in non-NMDA glutamate receptor channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 4080-7. PMID 1357118 DOI: 10.1523/Jneurosci.12-10-04080.1992 |
0.776 |
|
| 1992 |
McBain C, Dingledine R. Dual-component miniature excitatory synaptic currents in rat hippocampal CA3 pyramidal neurons. Journal of Neurophysiology. 68: 16-27. PMID 1355525 |
0.705 |
|
| 1992 |
Boulter J, Bettler B, Dingledine R, Edgebjerg J, Hartley M, Hermans-Borgmeyer I, Hollmann M, Hume RI, Rogers S, Heinemann S. Molecular biology of the glutamate receptors. Clinical Neuropharmacology. 15: 60A-61A. PMID 1323407 DOI: 10.1097/00002826-199201001-00033 |
0.385 |
|
| 1991 |
Boland LM, Allen AC, Dingledine R. Inhibition by bradykinin of voltage-activated barium current in a rat dorsal root ganglion cell line: role of protein kinase C. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 1140-9. PMID 2010809 DOI: 10.1523/Jneurosci.11-04-01140.1991 |
0.59 |
|
| 1991 |
Boland LM, Brown TA, Dingledine R. Gadolinium block of calcium channels: influence of bicarbonate. Brain Research. 563: 142-50. PMID 1786527 DOI: 10.1016/0006-8993(91)91527-8 |
0.597 |
|
| 1991 |
Dingledine R. New wave of non-NMDA excitatory amino acid receptors. Trends in Pharmacological Sciences. 12: 360-2. PMID 1662419 DOI: 10.1016/0165-6147(91)90602-O |
0.342 |
|
| 1991 |
Dingledine R, Kleckner NW, McBain CJ. Excitatory amino acid receptors in the Xenopus oocyte expression system. Advances in Experimental Medicine and Biology. 287: 441-53. PMID 1662015 DOI: 10.1007/978-1-4684-5907-4_39 |
0.806 |
|
| 1991 |
Hume RI, Dingledine R, Heinemann SF. Identification of a site in glutamate receptor subunits that controls calcium permeability. Science (New York, N.Y.). 253: 1028-31. PMID 1653450 DOI: 10.1126/Science.1653450 |
0.786 |
|
| 1990 |
McBain CJ, Traynelis SF, Dingledine R. Regional variation of extracellular space in the hippocampus. Science (New York, N.Y.). 249: 674-7. PMID 2382142 DOI: 10.1126/Science.2382142 |
0.75 |
|
| 1990 |
Dingledine R, McBain CJ, McNamara JO. Excitatory amino acid receptors in epilepsy. Trends in Pharmacological Sciences. 11: 334-8. PMID 2168104 DOI: 10.1016/0165-6147(90)90238-4 |
0.777 |
|
| 1990 |
Dingledine R, Myers SJ, Nicholas RA. Molecular biology of mammalian amino acid receptors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 4: 2636-45. PMID 2161372 DOI: 10.1096/Fasebj.4.9.2161372 |
0.403 |
|
| 1990 |
Kawasaki K, Traynelis SF, Dingledine R. Different responses of CA1 and CA3 regions to hypoxia in rat hippocampal slice. Journal of Neurophysiology. 63: 385-94. PMID 2158521 DOI: 10.1152/Jn.1990.63.3.385 |
0.565 |
|
| 1990 |
Boland LM, Dingledine R. Multiple components of both transient and sustained barium currents in a rat dorsal root ganglion cell line. The Journal of Physiology. 420: 223-45. PMID 2157839 DOI: 10.1113/jphysiol.1990.sp017909 |
0.578 |
|
| 1990 |
Dingledine R, Kleckner NW, McBain CJ. The glycine coagonist site of the NMDA receptor. Advances in Experimental Medicine and Biology. 268: 17-26. PMID 2150150 DOI: 10.1007/978-1-4684-5769-8_3 |
0.799 |
|
| 1990 |
McNamara D, Smith EC, Calligaro DO, O'Malley PJ, McQuaid LA, Dingledine R. 5,7-Dichlorokynurenic acid, a potent and selective competitive antagonist of the glycine site on NMDA receptors. Neuroscience Letters. 120: 17-20. PMID 2149877 DOI: 10.1016/0304-3940(90)90157-5 |
0.418 |
|
| 1990 |
McNamara D, Dingledine R. Dual effect of glycine on NMDA-induced neurotoxicity in rat cortical cultures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 3970-6. PMID 1980134 DOI: 10.1523/Jneurosci.10-12-03970.1990 |
0.36 |
|
| 1990 |
Dawson TL, Nicholas RA, Dingledine R. Homomeric GluR1 excitatory amino acid receptors expressed in Xenopus oocytes. Molecular Pharmacology. 38: 779-84. PMID 1979144 |
0.315 |
|
| 1990 |
Chamberlin NL, Traub RD, Dingledine R. Role of EPSPs in initiation of spontaneous synchronized burst firing in rat hippocampal neurons bathed in high potassium. Journal of Neurophysiology. 64: 1000-8. PMID 1977893 DOI: 10.1152/Jn.1990.64.3.1000 |
0.348 |
|
| 1990 |
Boland LM, Dingledine R. Expression of sensory neuron antigens by a dorsal root ganglion cell line, F-11. Brain Research. Developmental Brain Research. 51: 259-66. PMID 1969775 DOI: 10.1016/0165-3806(90)90284-6 |
0.571 |
|
| 1990 |
Kawasaki K, Traynelis SF, Dingledine R. Epilepsy, human and experimentalHypoxia-induced different responses in CA1 and CA3 regions of the rat hippocampal slice Neuroscience Research Supplements. 11. DOI: 10.1016/0921-8696(90)90589-U |
0.538 |
|
| 1990 |
Kawasaki K, Traynelis SF, Dingledine R. Hypoxia-induced different responses in CA1 and CA3 regions of the rat hippocampal slice Neuroscience Research Supplements. 15: S45. DOI: 10.1016/0921-8696(90)90166-Z |
0.525 |
|
| 1990 |
McBain CJ, Traynelis SF, Dingledine R. The volume fraction of rat hippocampal extracellular space in vitro displays marked subfield variation Journal of Physiology. 426: 49P. |
0.709 |
|
| 1989 |
Traynelis SF, Dingledine R. Role of extracellular space in hyperosmotic suppression of potassium-induced electrographic seizures. Journal of Neurophysiology. 61: 927-38. PMID 2723735 DOI: 10.1152/Jn.1989.61.5.927 |
0.565 |
|
| 1989 |
Traynelis SF, Dingledine R, McNamara JO, Butler L, Rigsbee L. Effect of kindling on potassium-induced electrographic seizures in vitro. Neuroscience Letters. 105: 326-32. PMID 2594218 DOI: 10.1016/0304-3940(89)90642-3 |
0.658 |
|
| 1989 |
Traynelis SF, Dingledine R. Modification of potassium-induced interictal bursts and electrographic seizures by divalent cations. Neuroscience Letters. 98: 194-9. PMID 2565567 DOI: 10.1016/0304-3940(89)90509-0 |
0.579 |
|
| 1989 |
Verdoorn TA, Kleckner NW, Dingledine R. N-methyl-D-aspartate/glycine and quisqualate/kainate receptors expressed in Xenopus oocytes: antagonist pharmacology. Molecular Pharmacology. 35: 360-8. PMID 2564633 |
0.716 |
|
| 1989 |
McBain CJ, Kleckner NW, Wyrick S, Dingledine R. Structural requirements for activation of the glycine coagonist site of N-methyl-D-aspartate receptors expressed in Xenopus oocytes. Molecular Pharmacology. 36: 556-65. PMID 2554111 |
0.67 |
|
| 1989 |
Kleckner NW, Dingledine R. Selectivity of quinoxalines and kynurenines as antagonists of the glycine site on N-methyl-D-aspartate receptors. Molecular Pharmacology. 36: 430-6. PMID 2550776 |
0.335 |
|
| 1988 |
Chamberlin NL, Dingledine R. GABAergic inhibition and the induction of spontaneous epileptiform activity by low chloride and high potassium in the hippocampal slice. Brain Research. 445: 12-8. PMID 3365550 DOI: 10.1016/0006-8993(88)91068-2 |
0.304 |
|
| 1988 |
Traynelis SF, Dingledine R. Potassium-induced spontaneous electrographic seizures in the rat hippocampal slice. Journal of Neurophysiology. 59: 259-76. PMID 3343603 DOI: 10.1152/Jn.1988.59.1.259 |
0.565 |
|
| 1988 |
Verdoorn TA, Dingledine R. Excitatory amino acid receptors expressed in Xenopus oocytes: agonist pharmacology. Molecular Pharmacology. 34: 298-307. PMID 2901662 |
0.718 |
|
| 1988 |
Kleckner NW, Dingledine R. Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes. Science (New York, N.Y.). 241: 835-7. PMID 2841759 DOI: 10.1126/Science.2841759 |
0.685 |
|
| 1988 |
Dingledine R, Boland LM, Chamberlin NL, Kawasaki K, Kleckner NW, Traynelis SF, Verdoorn TA. Amino acid receptors and uptake systems in the mammalian central nervous system. Critical Reviews in Neurobiology. 4: 1-96. PMID 2461808 |
0.818 |
|
| 1988 |
Berry BW, Boland LM, Hoch DB, Dingledine R. L-glutamate binding site on N18-RE-105 neuroblastoma hybrid cells is not coupled to an ion channel. Journal of Neurochemistry. 51: 1176-83. PMID 2458433 DOI: 10.1111/j.1471-4159.1988.tb03084.x |
0.629 |
|
| 1987 |
Korn SJ, Giacchino JL, Chamberlin NL, Dingledine R. Epileptiform burst activity induced by potassium in the hippocampus and its regulation by GABA-mediated inhibition. Journal of Neurophysiology. 57: 325-40. PMID 3559679 DOI: 10.1152/Jn.1987.57.1.325 |
0.803 |
|
| 1987 |
Dingledine R, Roth AA, King GL. Synaptic control of pyramidal cell activation in the hippocampal slice preparation in the rat. Neuroscience. 22: 553-61. PMID 3313098 DOI: 10.1016/0306-4522(87)90352-6 |
0.33 |
|
| 1987 |
Verdoorn TA, Kleckner NW, Dingledine R. Rat brain N-methyl-D-aspartate receptors expressed in Xenopus oocytes. Science (New York, N.Y.). 238: 1114-6. PMID 2825347 DOI: 10.1126/Science.2825347 |
0.815 |
|
| 1986 |
Korn SJ, Dingledine R. Prolongation of gamma-aminobutyric acid-mediated inhibitory postsynaptic potentials by 4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridin-3-ol (THPO). Neuroscience Letters. 64: 47-52. PMID 3960387 DOI: 10.1016/0304-3940(86)90661-0 |
0.652 |
|
| 1986 |
Korn SJ, Dingledine R. Inhibition of GABA uptake in the rat hippocampal slice. Brain Research. 368: 247-55. PMID 3697725 DOI: 10.1016/0006-8993(86)90569-X |
0.669 |
|
| 1986 |
Hoch DB, Dingledine R. GABAergic neurons in rat hippocampal culture. Brain Research. 390: 53-64. PMID 3512041 DOI: 10.1016/0165-3806(86)90151-3 |
0.329 |
|
| 1986 |
Dingledine R, Hynes MA, King GL. Involvement of N-methyl-D-aspartate receptors in epileptiform bursting in the rat hippocampal slice. The Journal of Physiology. 380: 175-89. PMID 2886653 DOI: 10.1113/jphysiol.1986.sp016279 |
0.408 |
|
| 1986 |
King GL, Dingledine R. Evidence for the activation of the N-methyl-D-aspartate receptor during epileptiform discharge. Advances in Experimental Medicine and Biology. 203: 465-74. PMID 2878569 DOI: 10.1007/978-1-4684-7971-3_35 |
0.368 |
|
| 1986 |
Dingledine R. NMDA Receptors: what do they do? Trends in Neurosciences. 9: 47-49. DOI: 10.1016/0166-2236(86)90017-2 |
0.446 |
|
| 1985 |
King GL, Dingledine R, Giacchino JL, McNamara JO. Abnormal neuronal excitability in hippocampal slices from kindled rats. Journal of Neurophysiology. 54: 1295-304. PMID 3001236 DOI: 10.1152/Jn.1985.54.5.1295 |
0.762 |
|
| 1985 |
King GL, Knox JJ, Dingledine R. Reduction of inhibition by a benzodiazepine antagonist, Ro15-1788, in the rat hippocampal slice. Neuroscience. 15: 371-8. PMID 2991811 DOI: 10.1016/0306-4522(85)90219-2 |
0.399 |
|
| 1985 |
Dingledine R, Korn SJ. Gamma-aminobutyric acid uptake and the termination of inhibitory synaptic potentials in the rat hippocampal slice. The Journal of Physiology. 366: 387-409. PMID 2414435 DOI: 10.1113/jphysiol.1985.sp015804 |
0.646 |
|
| 1983 |
Dingledine R, Valentino RJ, Bostock E, King ME, Chang KJ. Down-regulation of delta but not mu opioid receptors in the hippocampal slice associated with loss of physiological response. Life Sciences. 33: 333-6. PMID 6319888 DOI: 10.1016/0024-3205(83)90510-6 |
0.612 |
|
| 1983 |
Dingledine R. N-methyl aspartate activates voltage-dependent calcium conductance in rat hippocampal pyramidal cells. The Journal of Physiology. 343: 385-405. PMID 6139475 DOI: 10.1113/jphysiol.1983.sp014899 |
0.343 |
|
| 1982 |
Valentino RJ, Dingledine R. Pharmacological characterization of opioid effects in the rat hippocampal slice. The Journal of Pharmacology and Experimental Therapeutics. 223: 502-9. PMID 6752374 |
0.503 |
|
| 1982 |
Valentino RJ, Bostock E, Dingledine R. Opioid pharmacology in the rat hippocampal slice. Life Sciences. 31: 2339-42. PMID 6131361 DOI: 10.1016/0024-3205(82)90151-5 |
0.58 |
|
| 1981 |
Dingledine R. Possible mechanisms of enkephalin action on hippocampal CA1 pyramidal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 1: 1022-35. PMID 7026738 DOI: 10.1523/Jneurosci.01-09-01022.1981 |
0.342 |
|
| 1981 |
Valentino RJ, Dingledine R. Presynaptic inhibitory effect of acetylcholine in the hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 1: 784-92. PMID 6286902 DOI: 10.1523/Jneurosci.01-07-00784.1981 |
0.576 |
|
| 1981 |
Dodd J, Dingledine R, Kelly JS. The excitatory action of acetylcholine on hippocampal neurones of the guinea pig and rat maintained in vitro. Brain Research. 207: 109-27. PMID 6258725 DOI: 10.1016/0006-8993(81)90682-X |
0.507 |
|
| 1980 |
Andersen P, Dingledine R, Gjerstad L, Langmoen IA, Laursen AM. Two different responses of hippocampal pyramidal cells to application of gamma-amino butyric acid. The Journal of Physiology. 305: 279-96. PMID 7441554 DOI: 10.1113/jphysiol.1980.sp013363 |
0.503 |
|
| 1980 |
Dingledine R, Langmoen IA. Conductance changes and inhibitory actions of hippocampal recurrent IPSPs. Brain Research. 185: 277-87. PMID 7357430 DOI: 10.1016/0006-8993(80)91068-9 |
0.331 |
|
| 1980 |
Dingledine R, Dodd J, Kelly JS. The in vitro brain slice as a useful neurophysiological preparation for intracellular recording. Journal of Neuroscience Methods. 2: 323-62. PMID 6106092 DOI: 10.1016/0165-0270(80)90002-3 |
0.477 |
|
| 1979 |
Dingledine R, Gjerstad L. Penicillin blocks hippocampal IPSPs, unmasking prolonged EPSPs. Brain Research. 168: 205-9. PMID 455081 DOI: 10.1016/0006-8993(79)90141-0 |
0.335 |
|
| 1979 |
Kelly JS, Dodd J, Dingledine R. Acetylcholine as an excitatory and inhibitory transmitter in the mammalian central nervous system. Progress in Brain Research. 49: 253-66. PMID 229514 DOI: 10.1016/S0079-6123(08)64638-5 |
0.526 |
|
| 1978 |
Dingledine R, Iversen LL, Breuker E. Naloxone as a GABA antagonist: evidence from iontophoretic, receptor binding and convulsant studies. European Journal of Pharmacology. 47: 19-27. PMID 618728 DOI: 10.1016/0014-2999(78)90369-2 |
0.371 |
|
| 1977 |
Dingledine R, Kelly JS. Brain stem stimulation and the acetylcholine-evoked inhibition of neurones in the feline nucleus reticularis thalami. The Journal of Physiology. 271: 135-54. PMID 915830 DOI: 10.1113/jphysiol.1977.sp011994 |
0.5 |
|
| 1977 |
Dingledine R, Dodd J, Kelly JS. Intracellular recording from pyramidal neurones in the in vitro transverse hippocampal slice [proceedings]. The Journal of Physiology. 269: 13P-15P. PMID 894533 |
0.433 |
|
| 1977 |
Ross M, Dingledine R, Cox BM, Goldstein A. Distribution of endorphins (peptides with morphine-like pharmacological activity) in pituitary. Brain Research. 124: 523-32. PMID 851863 DOI: 10.1016/0006-8993(77)90951-9 |
0.65 |
|
| 1977 |
Dingledine R, Kelly JS. Midbrain reticular evoked inhibition of thalamic neurones [proceedings]. The Journal of Physiology. 265: 46P-47P. PMID 850185 |
0.4 |
|
| 1977 |
Dingledine R, Dodd J, Kelly JS. Ach-evoked excitation of cortical neurones [proceedings]. The Journal of Physiology. 273: 79P-80P. PMID 599477 |
0.386 |
|
| 1976 |
Ben-Ari Y, Dingledine R, Kanazawa I, Kelly JS. Inhibitory effects of acetylcholine on neurones in the feline nucleus reticularis thalami. The Journal of Physiology. 261: 647-71. PMID 978591 DOI: 10.1113/jphysiol.1976.sp011579 |
0.429 |
|
| 1976 |
Iversen L, Dingledine R. Enkephalin: the latest instalment Nature. 262: 738-739. DOI: 10.1038/262738a0 |
0.621 |
|
| 1975 |
Dingledine R, Goldstein A. Single neuron studies of opiate action in the guinea pig myenteric plexus. Life Sciences. 17: 57-62. PMID 1143011 DOI: 10.1016/0024-3205(75)90235-0 |
0.575 |
|
| 1974 |
Dingledine R, Goldstein A, Kendig J. Effects of narcotic opiates and serotonin on the electrical behavior of neurons in the guinea pig myenteric plexus. Life Sciences. 14: 2299-309. PMID 4847817 DOI: 10.1016/0024-3205(74)90111-8 |
0.561 |
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| 1973 |
Dingledine R, Goldstein A. Lethality of the morphinan isomers levorphanol and dextrorphan. British Journal of Pharmacology. 48: 718-20. PMID 4788214 DOI: 10.1111/j.1476-5381.1973.tb08261.x |
0.514 |
|
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