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Kim Nasmyth - Publications

Affiliations: 
Biochemistry University of Oxford, Oxford, United Kingdom 
Website:
http://www.bioch.ox.ac.uk/aspsite/index.asp?pageid=591

233 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Nasmyth KA, Lee BG, Roig MB, Löwe J. What AlphaFold tells us about cohesin's retention on and release from chromosomes. Elife. 12. PMID 37975572 DOI: 10.7554/eLife.88656  0.327
2021 Houlard M, Cutts EE, Shamim MS, Godwin J, Weisz D, Presser Aiden A, Lieberman Aiden E, Schermelleh L, Vannini A, Nasmyth K. MCPH1 inhibits Condensin II during interphase by regulating its SMC2-Kleisin interface. Elife. 10. PMID 34850681 DOI: 10.7554/eLife.73348  0.393
2021 Ogushi S, Rattani A, Godwin J, Metson J, Schermelleh L, Nasmyth K. Loss of sister kinetochore co-orientation and peri-centromeric cohesin protection after meiosis I depends on cleavage of centromeric REC8. Developmental Cell. 56: 3100-3114.e4. PMID 34758289 DOI: 10.1016/j.devcel.2021.10.017  0.309
2020 Srinivasan M, Fumasoni M, Petela NJ, Murray A, Nasmyth KA. Cohesion is established during DNA replication utilising chromosome associated cohesin rings as well as those loaded de novo onto nascent DNAs. Elife. 9. PMID 32515737 DOI: 10.7554/Elife.56611  0.367
2020 Rhodes JDP, Feldmann A, Hernández-Rodríguez B, Díaz N, Brown JM, Fursova NA, Blackledge NP, Prathapan P, Dobrinic P, Huseyin MK, Szczurek A, Kruse K, Nasmyth KA, Buckle VJ, Vaquerizas JM, et al. Cohesin Disrupts Polycomb-Dependent Chromosome Interactions in Embryonic Stem Cells. Cell Reports. 30: 820-835.e10. PMID 31968256 DOI: 10.1016/j.celrep.2019.12.057  0.341
2019 Yatskevich S, Rhodes J, Nasmyth K. Organization of Chromosomal DNA by SMC Complexes. Annual Review of Genetics. PMID 31577909 DOI: 10.1146/Annurev-Genet-112618-043633  0.437
2019 Srinivasan M, Petela NJ, Scheinost JC, Collier J, Voulgaris M, B Roig M, Beckouët F, Hu B, Nasmyth KA. Scc2 counteracts a Wapl-independent mechanism that releases cohesin from chromosomes during G1. Elife. 8. PMID 31225797 DOI: 10.7554/eLife.44736  0.338
2019 Chapard C, Jones R, van Oepen T, Scheinost JC, Nasmyth K. Sister DNA Entrapment between Juxtaposed Smc Heads and Kleisin of the Cohesin Complex. Molecular Cell. PMID 31201089 DOI: 10.1016/J.Molcel.2019.05.023  0.327
2019 Bürmann F, Lee BG, Than T, Sinn L, O'Reilly FJ, Yatskevich S, Rappsilber J, Hu B, Nasmyth K, Löwe J. A folded conformation of MukBEF and cohesin. Nature Structural & Molecular Biology. PMID 30833788 DOI: 10.1038/s41594-019-0196-z  0.341
2019 Bürmann F, Lee B, Than T, Sinn L, O'Reilly FJ, Yatskevich S, Rappsilber J, Hu B, Nasmyth K, Löwe J. A folded conformation of MukBEF and cohesin. Nature Structural & Molecular Biology. 26: 227-236. DOI: 10.2210/Pdb6H2X/Pdb  0.448
2017 Nasmyth K. How are DNAs woven into chromosomes? Science (New York, N.Y.). 358: 589-590. PMID 29097534 DOI: 10.1126/Science.Aap8729  0.443
2017 Rhodes JDP, Haarhuis JHI, Grimm JB, Rowland BD, Lavis LD, Nasmyth KA. Cohesin Can Remain Associated with Chromosomes during DNA Replication. Cell Reports. 20: 2749-2755. PMID 28930671 DOI: 10.1016/J.Celrep.2017.08.092  0.33
2017 Rhodes JD, Mazza D, Nasmyth KA, Uphoff S. Scc2/Nipbl hops between chromosomal cohesin rings after loading. Elife. 6. PMID 28914604 DOI: 10.7554/eLife.30000  0.331
2017 Rattani A, Ballesteros Mejia R, Roberts K, Roig MB, Godwin J, Hopkins M, Eguren M, Sanchez-Pulido L, Okaz E, Ogushi S, Wolna M, Metson J, Pendás AM, Malumbres M, Novák B, ... ... Nasmyth K, et al. APC/C(Cdh1) Enables Removal of Shugoshin-2 from the Arms of Bivalent Chromosomes by Moderating Cyclin-Dependent Kinase Activity. Current Biology : Cb. PMID 28502659 DOI: 10.1016/J.Cub.2017.04.023  0.442
2017 Wells JN, Gligoris TG, Nasmyth KA, Marsh JA. Evolution of condensin and cohesin complexes driven by replacement of Kite by Hawk proteins. Current Biology : Cb. 27: R17-R18. PMID 28073014 DOI: 10.1016/j.cub.2016.11.050  0.351
2017 Rhodes J, Mazza D, Nasmyth K, Uphoff S. Author response: Scc2/Nipbl hops between chromosomal cohesin rings after loading Elife. DOI: 10.7554/Elife.30000.020  0.318
2016 Cosma MP, Tanaka T, Nasmyth K. Ordered Recruitment of Transcription and Chromatin Remodeling Factors to a Cell Cycle- and Developmentally Regulated Promoter. Cell. 166: 781. PMID 27471970 DOI: 10.1016/J.Cell.2016.07.016  0.368
2016 Lee BG, Roig MB, Jansma M, Petela N, Metson J, Nasmyth K, Löwe J. Crystal Structure of the Cohesin Gatekeeper Pds5 and in Complex with Kleisin Scc1. Cell Reports. PMID 26923598 DOI: 10.1016/J.Celrep.2016.02.020  0.345
2016 Elbatsh AM, Haarhuis JH, Petela N, Chapard C, Fish A, Celie PH, Stadnik M, Ristic D, Wyman C, Medema RH, Nasmyth K, Rowland BD. Cohesin Releases DNA through Asymmetric ATPase-Driven Ring Opening. Molecular Cell. 61: 575-88. PMID 26895426 DOI: 10.1016/J.Molcel.2016.01.025  0.421
2016 Beckouët F, Srinivasan M, Roig MB, Chan KL, Scheinost JC, Batty P, Hu B, Petela N, Gligoris T, Smith AC, Strmecki L, Rowland BD, Nasmyth K. Releasing Activity Disengages Cohesin's Smc3/Scc1 Interface in a Process Blocked by Acetylation. Molecular Cell. 61: 563-74. PMID 26895425 DOI: 10.1016/J.Molcel.2016.01.026  0.386
2016 Rattani A, Mejia RB, Roberts K, Roig MB, Godwin J, Eguren M, Ogushi S, Okaz E, Pendas A, Marcos M, Herbert M, Nasmyth K. Abstract PR11: APC/CCdh1 maintains primordial follicles, germinal vesicle arrest and ensures balanced segregation of chromosomes by enabling removal of Shugoshin-2 from chromosomes arms Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Cellcycle16-Pr11  0.479
2015 Hu B, Petela N, Kurze A, Chan KL, Chapard C, Nasmyth K. Biological chromodynamics: a general method for measuring protein occupancy across the genome by calibrating ChIP-seq. Nucleic Acids Research. PMID 26130708 DOI: 10.1093/Nar/Gkv670  0.357
2015 Houlard M, Godwin J, Metson J, Lee J, Hirano T, Nasmyth K. Condensin confers the longitudinal rigidity of chromosomes. Nature Cell Biology. 17: 771-81. PMID 25961503 DOI: 10.1038/Ncb3167  0.446
2014 Gligoris TG, Scheinost JC, Bürmann F, Petela N, Chan KL, Uluocak P, Beckouët F, Gruber S, Nasmyth K, Löwe J. Closing the cohesin ring: structure and function of its Smc3-kleisin interface. Science (New York, N.Y.). 346: 963-7. PMID 25414305 DOI: 10.1126/Science.1256917  0.434
2014 Oliveira RA, Kotadia S, Tavares A, Mirkovic M, Bowlin K, Eichinger CS, Nasmyth K, Sullivan W. Centromere-independent accumulation of cohesin at ectopic heterochromatin sites induces chromosome stretching during anaphase. Plos Biology. 12: e1001962. PMID 25290697 DOI: 10.1371/Journal.Pbio.1001962  0.758
2014 Roig MB, Löwe J, Chan KL, Beckouët F, Metson J, Nasmyth K. Structure and function of cohesin's Scc3/SA regulatory subunit. Febs Letters. 588: 3692-702. PMID 25171859 DOI: 10.2210/Pdb4Uvj/Pdb  0.432
2014 Rattani A, Vinod PK, Godwin J, Tachibana-Konwalski K, Wolna M, Malumbres M, Novák B, Nasmyth K. Dependency of the spindle assembly checkpoint on Cdk1 renders the anaphase transition irreversible. Current Biology : Cb. 24: 630-7. PMID 24583015 DOI: 10.1016/J.Cub.2014.01.033  0.427
2013 Tachibana-Konwalski K, Godwin J, Borsos M, Rattani A, Adams DJ, Nasmyth K. Spindle assembly checkpoint of oocytes depends on a kinetochore structure determined by cohesin in meiosis I. Current Biology : Cb. 23: 2534-9. PMID 24291092 DOI: 10.1016/J.Cub.2013.10.052  0.474
2013 Rattani A, Wolna M, Ploquin M, Helmhart W, Morrone S, Mayer B, Godwin J, Xu W, Stemmann O, Pendas A, Nasmyth K. Sgol2 provides a regulatory platform that coordinates essential cell cycle processes during meiosis I in oocytes. Elife. 2: e01133. PMID 24192037 DOI: 10.7554/Elife.01133  0.386
2013 Oliveira RA, Nasmyth K. Cohesin cleavage is insufficient for centriole disengagement in Drosophila. Current Biology : Cb. 23: R601-3. PMID 23885871 DOI: 10.1016/J.Cub.2013.04.003  0.76
2013 Chan KL, Gligoris T, Upcher W, Kato Y, Shirahige K, Nasmyth K, Beckouët F. Pds5 promotes and protects cohesin acetylation. Proceedings of the National Academy of Sciences of the United States of America. 110: 13020-5. PMID 23878248 DOI: 10.1073/Pnas.1306900110  0.426
2013 Eichinger CS, Kurze A, Oliveira RA, Nasmyth K. Disengaging the Smc3/kleisin interface releases cohesin from Drosophila chromosomes during interphase and mitosis. The Embo Journal. 32: 656-65. PMID 23340528 DOI: 10.1038/Emboj.2012.346  0.756
2013 Rattani A, Wolna M, Ploquin M, Helmhart W, Morrone S, Mayer B, Godwin J, Xu W, Stemmann O, Pendas A, Nasmyth K. Author response: Sgol2 provides a regulatory platform that coordinates essential cell cycle processes during meiosis I in oocytes Elife. DOI: 10.7554/Elife.01133.028  0.371
2012 Touati SA, Cladière D, Lister LM, Leontiou I, Chambon JP, Rattani A, Böttger F, Stemmann O, Nasmyth K, Herbert M, Wassmann K. Cyclin A2 is required for sister chromatid segregation, but not separase control, in mouse oocyte meiosis. Cell Reports. 2: 1077-87. PMID 23122964 DOI: 10.1016/J.Celrep.2012.10.002  0.385
2012 Chan KL, Roig MB, Hu B, Beckouët F, Metson J, Nasmyth K. Cohesin's DNA exit gate is distinct from its entrance gate and is regulated by acetylation. Cell. 150: 961-74. PMID 22901742 DOI: 10.1016/j.cell.2012.07.028  0.335
2011 Hunt T, Nasmyth K, Novák B. The cell cycle. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 366: 3494-7. PMID 22084376 DOI: 10.1098/Rstb.2011.0274  0.351
2011 Farcas AM, Uluocak P, Helmhart W, Nasmyth K. Cohesin's concatenation of sister DNAs maintains their intertwining. Molecular Cell. 44: 97-107. PMID 21981921 DOI: 10.1016/J.Molcel.2011.07.034  0.423
2011 Nasmyth K. Cohesin: a catenase with separate entry and exit gates? Nature Cell Biology. 13: 1170-7. PMID 21968990 DOI: 10.1038/Ncb2349  0.411
2011 Seitan VC, Hao B, Tachibana-Konwalski K, Lavagnolli T, Mira-Bontenbal H, Brown KE, Teng G, Carroll T, Terry A, Horan K, Marks H, Adams DJ, Schatz DG, Aragon L, Fisher AG, ... ... Nasmyth K, et al. A role for cohesin in T-cell-receptor rearrangement and thymocyte differentiation. Nature. 476: 467-71. PMID 21832993 DOI: 10.1038/Nature10312  0.502
2011 Kuczera T, Stilling RM, Hsia HE, Bahari-Javan S, Irniger S, Nasmyth K, Sananbenesi F, Fischer A. The anaphase promoting complex is required for memory function in mice. Learning & Memory (Cold Spring Harbor, N.Y.). 18: 49-57. PMID 21191042 DOI: 10.1101/Lm.1998411  0.322
2011 Hu B, Itoh T, Mishra A, Katoh Y, Chan KL, Upcher W, Godlee C, Roig MB, Shirahige K, Nasmyth K. ATP hydrolysis is required for relocating cohesin from sites occupied by its Scc2/4 loading complex. Current Biology : Cb. 21: 12-24. PMID 21185190 DOI: 10.1016/J.Cub.2010.12.004  0.401
2011 Kurze A, Michie KA, Dixon SE, Mishra A, Itoh T, Khalid S, Strmecki L, Shirahige K, Haering CH, Löwe J, Nasmyth K. A positively charged channel within the Smc1/Smc3 hinge required for sister chromatid cohesion. The Embo Journal. 30: 364-78. PMID 21139566 DOI: 10.1038/Emboj.2010.315  0.367
2010 Nasmyth K, Oliveira RA. Splitting the nucleus: what's wrong with the tripartite ring model? Cold Spring Harbor Symposia On Quantitative Biology. 75: 375-88. PMID 21209385 DOI: 10.1101/Sqb.2010.75.019  0.768
2010 Oliveira RA, Nasmyth K. Getting through anaphase: splitting the sisters and beyond. Biochemical Society Transactions. 38: 1639-44. PMID 21118140 DOI: 10.1042/Bst0381639  0.753
2010 Nasmyth K. How far will we see in the future? Molecular Biology of the Cell. 21: 3813-4. PMID 21079025 DOI: 10.1091/Mbc.E10-04-0359  0.383
2010 Tachibana-Konwalski K, Godwin J, van der Weyden L, Champion L, Kudo NR, Adams DJ, Nasmyth K. Rec8-containing cohesin maintains bivalents without turnover during the growing phase of mouse oocytes. Genes & Development. 24: 2505-16. PMID 20971813 DOI: 10.1101/Gad.605910  0.453
2010 Pauli A, van Bemmel JG, Oliveira RA, Itoh T, Shirahige K, van Steensel B, Nasmyth K. A direct role for cohesin in gene regulation and ecdysone response in Drosophila salivary glands. Current Biology : Cb. 20: 1787-98. PMID 20933422 DOI: 10.1016/J.Cub.2010.09.006  0.723
2010 Beckouët F, Hu B, Roig MB, Sutani T, Komata M, Uluocak P, Katis VL, Shirahige K, Nasmyth K. An Smc3 acetylation cycle is essential for establishment of sister chromatid cohesion. Molecular Cell. 39: 689-99. PMID 20832721 DOI: 10.1016/J.Molcel.2010.08.008  0.499
2010 Hamilton RS, Parton RM, Oliveira RA, Vendra G, Ball G, Nasmyth K, Davis I. ParticleStats: open source software for the analysis of particle motility and cytoskeletal polarity. Nucleic Acids Research. 38: W641-6. PMID 20542911 DOI: 10.1093/Nar/Gkq542  0.704
2010 Hutchins JR, Toyoda Y, Hegemann B, Poser I, Hériché JK, Sykora MM, Augsburg M, Hudecz O, Buschhorn BA, Bulkescher J, Conrad C, Comartin D, Schleiffer A, Sarov M, Pozniakovsky A, ... ... Nasmyth K, et al. Systematic analysis of human protein complexes identifies chromosome segregation proteins. Science (New York, N.Y.). 328: 593-9. PMID 20360068 DOI: 10.1126/Science.1181348  0.449
2010 Katis VL, Lipp JJ, Imre R, Bogdanova A, Okaz E, Habermann B, Mechtler K, Nasmyth K, Zachariae W. Rec8 phosphorylation by casein kinase 1 and Cdc7-Dbf4 kinase regulates cohesin cleavage by separase during meiosis. Developmental Cell. 18: 397-409. PMID 20230747 DOI: 10.1016/J.Devcel.2010.01.014  0.445
2010 Mishra A, Hu B, Kurze A, Beckouët F, Farcas AM, Dixon SE, Katou Y, Khalid S, Shirahige K, Nasmyth K. Both interaction surfaces within cohesin's hinge domain are essential for its stable chromosomal association. Current Biology : Cb. 20: 279-89. PMID 20153193 DOI: 10.1016/J.Cub.2009.12.059  0.393
2010 Oliveira RA, Hamilton RS, Pauli A, Davis I, Nasmyth K. Cohesin cleavage and Cdk inhibition trigger formation of daughter nuclei. Nature Cell Biology. 12: 185-92. PMID 20081838 DOI: 10.1038/Ncb2018  0.777
2009 Nasmyth K, Haering CH. Cohesin: its roles and mechanisms. Annual Review of Genetics. 43: 525-58. PMID 19886810 DOI: 10.1146/Annurev-Genet-102108-134233  0.494
2009 Xu Z, Cetin B, Anger M, Cho US, Helmhart W, Nasmyth K, Xu W. Structure and function of the PP2A-shugoshin interaction. Molecular Cell. 35: 426-41. PMID 19716788 DOI: 10.1016/J.Molcel.2009.06.031  0.45
2009 Kudo NR, Anger M, Peters AH, Stemmann O, Theussl HC, Helmhart W, Kudo H, Heyting C, Nasmyth K. Role of cleavage by separase of the Rec8 kleisin subunit of cohesin during mammalian meiosis I. Journal of Cell Science. 122: 2686-98. PMID 19625504 DOI: 10.1242/Jcs.035287  0.416
2009 Rowland BD, Roig MB, Nishino T, Kurze A, Uluocak P, Mishra A, Beckouët F, Underwood P, Metson J, Imre R, Mechtler K, Katis VL, Nasmyth K. Building sister chromatid cohesion: smc3 acetylation counteracts an antiestablishment activity. Molecular Cell. 33: 763-74. PMID 19328069 DOI: 10.1016/J.Molcel.2009.02.028  0.392
2009 McGuinness BE, Anger M, Kouznetsova A, Gil-Bernabé AM, Helmhart W, Kudo NR, Wuensche A, Taylor S, Hoog C, Novak B, Nasmyth K. Regulation of APC/C activity in oocytes by a Bub1-dependent spindle assembly checkpoint. Current Biology : Cb. 19: 369-80. PMID 19249208 DOI: 10.1016/J.Cub.2009.01.064  0.413
2009 Nasmyth K. How does cohesin hold sister DNAs together? Comparative Biochemistry and Physiology Part a: Molecular & Integrative Physiology. 153: S41. DOI: 10.1016/J.Cbpa.2009.04.480  0.325
2008 Haering CH, Farcas AM, Arumugam P, Metson J, Nasmyth K. The cohesin ring concatenates sister DNA molecules. Nature. 454: 297-301. PMID 18596691 DOI: 10.1038/Nature07098  0.362
2008 Poser I, Sarov M, Hutchins JR, Hériché JK, Toyoda Y, Pozniakovsky A, Weigl D, Nitzsche A, Hegemann B, Bird AW, Pelletier L, Kittler R, Hua S, Naumann R, Augsburg M, ... ... Nasmyth K, et al. BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals. Nature Methods. 5: 409-15. PMID 18391959 DOI: 10.1038/Nmeth.1199  0.385
2008 Pauli A, Althoff F, Oliveira RA, Heidmann S, Schuldiner O, Lehner CF, Dickson BJ, Nasmyth K. Cell-type-specific TEV protease cleavage reveals cohesin functions in Drosophila neurons. Developmental Cell. 14: 239-51. PMID 18267092 DOI: 10.1016/J.Devcel.2007.12.009  0.747
2007 Gregan J, Zhang C, Rumpf C, Cipak L, Li Z, Uluocak P, Nasmyth K, Shokat KM. Construction of conditional analog-sensitive kinase alleles in the fission yeast Schizosaccharomyces pombe. Nature Protocols. 2: 2996-3000. PMID 18007635 DOI: 10.1038/Nprot.2007.447  0.341
2007 Ivanov D, Nasmyth K. A physical assay for sister chromatid cohesion in vitro. Molecular Cell. 27: 300-10. PMID 17643378 DOI: 10.1016/J.Molcel.2007.07.002  0.389
2007 Gregan J, Riedel CG, Pidoux AL, Katou Y, Rumpf C, Schleiffer A, Kearsey SE, Shirahige K, Allshire RC, Nasmyth K. The kinetochore proteins Pcs1 and Mde4 and heterochromatin are required to prevent merotelic orientation. Current Biology : Cb. 17: 1190-200. PMID 17627824 DOI: 10.1016/J.Cub.2007.06.044  0.501
2007 Gregan J, Riedel CG, Petronczki M, Cipak L, Rumpf C, Poser I, Buchholz F, Mechtler K, Nasmyth K. Tandem affinity purification of functional TAP-tagged proteins from human cells. Nature Protocols. 2: 1145-51. PMID 17546005 DOI: 10.1038/Nprot.2007.172  0.351
2006 Gregan J, Rabitsch PK, Rumpf C, Novatchkova M, Schleiffer A, Nasmyth K. High-throughput knockout screen in fission yeast. Nature Protocols. 1: 2457-64. PMID 17406492 DOI: 10.1038/Nprot.2006.385  0.334
2006 Gruber S, Arumugam P, Katou Y, Kuglitsch D, Helmhart W, Shirahige K, Nasmyth K. Evidence that loading of cohesin onto chromosomes involves opening of its SMC hinge. Cell. 127: 523-37. PMID 17081975 DOI: 10.1016/J.Cell.2006.08.048  0.42
2006 Arumugam P, Nishino T, Haering CH, Gruber S, Nasmyth K. Cohesin's ATPase activity is stimulated by the C-terminal Winged-Helix domain of its kleisin subunit. Current Biology : Cb. 16: 1998-2008. PMID 17055978 DOI: 10.1016/J.Cub.2006.09.002  0.365
2006 Petronczki M, Matos J, Mori S, Gregan J, Bogdanova A, Schwickart M, Mechtler K, Shirahige K, Zachariae W, Nasmyth K. Monopolar attachment of sister kinetochores at meiosis I requires casein kinase 1. Cell. 126: 1049-64. PMID 16990132 DOI: 10.1016/J.Cell.2006.07.029  0.506
2006 Kudo NR, Wassmann K, Anger M, Schuh M, Wirth KG, Xu H, Helmhart W, Kudo H, McKay M, Maro B, Ellenberg J, de Boer P, Nasmyth K. Resolution of chiasmata in oocytes requires separase-mediated proteolysis. Cell. 126: 135-46. PMID 16839882 DOI: 10.1016/J.Cell.2006.05.033  0.46
2006 Watrin E, Schleiffer A, Tanaka K, Eisenhaber F, Nasmyth K, Peters JM. Human Scc4 is required for cohesin binding to chromatin, sister-chromatid cohesion, and mitotic progression. Current Biology : Cb. 16: 863-74. PMID 16682347 DOI: 10.1016/J.Cub.2006.03.049  0.445
2006 Riedel CG, Katis VL, Katou Y, Mori S, Itoh T, Helmhart W, Gálová M, Petronczki M, Gregan J, Cetin B, Mudrak I, Ogris E, Mechtler K, Pelletier L, Buchholz F, ... ... Nasmyth K, et al. Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I. Nature. 441: 53-61. PMID 16541024 DOI: 10.1038/Nature04664  0.465
2006 Wirth KG, Wutz G, Kudo NR, Desdouets C, Zetterberg A, Taghybeeglu S, Seznec J, Ducos GM, Ricci R, Firnberg N, Peters JM, Nasmyth K. Separase: a universal trigger for sister chromatid disjunction but not chromosome cycle progression. The Journal of Cell Biology. 172: 847-60. PMID 16533945 DOI: 10.1083/Jcb.200506119  0.475
2005 Vaur S, Cubizolles F, Plane G, Genier S, Rabitsch PK, Gregan J, Nasmyth K, Vanoosthuyse V, Hardwick KG, Javerzat JP. Control of Shugoshin function during fission-yeast meiosis. Current Biology : Cb. 15: 2263-70. PMID 16360688 DOI: 10.1016/J.Cub.2005.11.034  0.494
2005 Ivanov D, Nasmyth K. A topological interaction between cohesin rings and a circular minichromosome. Cell. 122: 849-60. PMID 16179255 DOI: 10.1016/J.Cell.2005.07.018  0.397
2005 Gregan J, Rabitsch PK, Sakem B, Csutak O, Latypov V, Lehmann E, Kohli J, Nasmyth K. Novel genes required for meiotic chromosome segregation are identified by a high-throughput knockout screen in fission yeast. Current Biology : Cb. 15: 1663-9. PMID 16169489 DOI: 10.1016/J.Cub.2005.07.059  0.448
2005 Nasmyth K, Haering CH. The structure and function of SMC and kleisin complexes. Annual Review of Biochemistry. 74: 595-648. PMID 15952899 DOI: 10.1146/Annurev.Biochem.74.082803.133219  0.47
2005 Hamant O, Golubovskaya I, Meeley R, Fiume E, Timofejeva L, Schleiffer A, Nasmyth K, Cande WZ. A REC8-dependent plant Shugoshin is required for maintenance of centromeric cohesion during meiosis and has no mitotic functions. Current Biology : Cb. 15: 948-54. PMID 15916952 DOI: 10.1016/J.Cub.2005.04.049  0.457
2005 Nasmyth K. How might cohesin hold sister chromatids together? Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 360: 483-96. PMID 15897174 DOI: 10.1098/Rstb.2004.1604  0.431
2005 Yanagida M, Nasmyth K. Introduction: dissection and simplification of chromosome segregation. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 360: 481. PMID 15897173 DOI: 10.1098/Rstb.2005.1620  0.404
2005 Nasmyth K. How do so few control so many? Cell. 120: 739-46. PMID 15797376 DOI: 10.1016/J.Cell.2005.03.006  0.454
2005 McGuinness BE, Hirota T, Kudo NR, Peters JM, Nasmyth K. Shugoshin prevents dissociation of cohesin from centromeres during mitosis in vertebrate cells. Plos Biology. 3: e86. PMID 15737064 DOI: 10.1371/Journal.Pbio.0030086  0.513
2004 Katis VL, Matos J, Mori S, Shirahige K, Zachariae W, Nasmyth K. Spo13 facilitates monopolin recruitment to kinetochores and regulates maintenance of centromeric cohesion during yeast meiosis. Current Biology : Cb. 14: 2183-96. PMID 15620645 DOI: 10.1016/J.Cub.2004.12.020  0.516
2004 Haering CH, Schoffnegger D, Nishino T, Helmhart W, Nasmyth K, Löwe J. Structure and stability of cohesin's Smc1-kleisin interaction. Molecular Cell. 15: 951-64. PMID 15383284 DOI: 10.1016/J.Molcel.2004.08.030  0.388
2004 Heidmann D, Horn S, Heidmann S, Schleiffer A, Nasmyth K, Lehner CF. The Drosophila meiotic kleisin C(2)M functions before the meiotic divisions. Chromosoma. 113: 177-87. PMID 15375666 DOI: 10.1007/S00412-004-0305-5  0.39
2004 Riedel CG, Gregan J, Gruber S, Nasmyth K. Is chromatin remodeling required to build sister-chromatid cohesion? Trends in Biochemical Sciences. 29: 389-92. PMID 15288867 DOI: 10.1016/J.Tibs.2004.06.007  0.484
2004 Azzam R, Chen SL, Shou W, Mah AS, Alexandru G, Nasmyth K, Annan RS, Carr SA, Deshaies RJ. Phosphorylation by cyclin B-Cdk underlies release of mitotic exit activator Cdc14 from the nucleolus. Science (New York, N.Y.). 305: 516-9. PMID 15273393 DOI: 10.1126/Science.1099402  0.401
2004 Petronczki M, Chwalla B, Siomos MF, Yokobayashi S, Helmhart W, Deutschbauer AM, Davis RW, Watanabe Y, Nasmyth K. Sister-chromatid cohesion mediated by the alternative RF-CCtf18/Dcc1/Ctf8, the helicase Chl1 and the polymerase-alpha-associated protein Ctf4 is essential for chromatid disjunction during meiosis II. Journal of Cell Science. 117: 3547-59. PMID 15226378 DOI: 10.1242/Jcs.01231  0.503
2004 Bourbon HM, Aguilera A, Ansari AZ, Asturias FJ, Berk AJ, Bjorklund S, Blackwell TK, Borggrefe T, Carey M, Carlson M, Conaway JW, Conaway RC, Emmons SW, Fondell JD, Freedman LP, ... ... Nasmyth K, et al. A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II. Molecular Cell. 14: 553-7. PMID 15175151 DOI: 10.1016/J.Molcel.2004.05.011  0.567
2004 Nasmyth K, Schleiffer A. From a single double helix to paired double helices and back. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 359: 99-108. PMID 15065662 DOI: 10.1098/Rstb.2003.1417  0.457
2004 Katis VL, Galova M, Rabitsch KP, Gregan J, Nasmyth K. Maintenance of cohesin at centromeres after meiosis I in budding yeast requires a kinetochore-associated protein related to MEI-S332. Current Biology : Cb. 14: 560-72. PMID 15062096 DOI: 10.1016/J.Cub.2004.03.001  0.493
2004 Rabitsch KP, Gregan J, Schleiffer A, Javerzat JP, Eisenhaber F, Nasmyth K. Two fission yeast homologs of Drosophila Mei-S332 are required for chromosome segregation during meiosis I and II. Current Biology : Cb. 14: 287-301. PMID 14972679 DOI: 10.1016/J.Cub.2004.01.051  0.508
2004 Dewar H, Tanaka K, Nasmyth K, Tanaka TU. Tension between two kinetochores suffices for their bi-orientation on the mitotic spindle. Nature. 428: 93-7. PMID 14961024 DOI: 10.1038/Nature02328  0.404
2004 Wirth KG, Ricci R, Giménez-Abián JF, Taghybeeglu S, Kudo NR, Jochum W, Vasseur-Cognet M, Nasmyth K. Loss of the anaphase-promoting complex in quiescent cells causes unscheduled hepatocyte proliferation. Genes & Development. 18: 88-98. PMID 14724179 DOI: 10.1101/Gad.285404  0.442
2004 Wiederkehr C, Basavaraj R, Sarrauste de Menthière C, Hermida L, Koch R, Schlecht U, Amon A, Brachat S, Breitenbach M, Briza P, Caburet S, Cherry M, Davis R, Deutschbauer A, Dickinson HG, ... ... Nasmyth K, et al. GermOnline, a cross-species community knowledgebase on germ cell differentiation. Nucleic Acids Research. 32: D560-7. PMID 14681481 DOI: 10.1093/Nar/Gkh055  0.531
2003 Haering CH, Nasmyth K. Building and breaking bridges between sister chromatids. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 25: 1178-91. PMID 14635253 DOI: 10.1002/Bies.10361  0.476
2003 Arumugam P, Gruber S, Tanaka K, Haering CH, Mechtler K, Nasmyth K. ATP hydrolysis is required for cohesin's association with chromosomes. Current Biology : Cb. 13: 1941-53. PMID 14614819 DOI: 10.1016/J.Cub.2003.10.036  0.439
2003 Buonomo SB, Rabitsch KP, Fuchs J, Gruber S, Sullivan M, Uhlmann F, Petronczki M, Tóth A, Nasmyth K. Division of the nucleolus and its release of CDC14 during anaphase of meiosis I depends on separase, SPO12, and SLK19. Developmental Cell. 4: 727-39. PMID 12737807 DOI: 10.1016/S1534-5807(03)00129-1  0.487
2003 Clyne RK, Katis VL, Jessop L, Benjamin KR, Herskowitz I, Lichten M, Nasmyth K. Polo-like kinase Cdc5 promotes chiasmata formation and cosegregation of sister centromeres at meiosis I. Nature Cell Biology. 5: 480-5. PMID 12717442 DOI: 10.1038/Ncb977  0.498
2003 Rabitsch KP, Petronczki M, Javerzat JP, Genier S, Chwalla B, Schleiffer A, Tanaka TU, Nasmyth K. Kinetochore recruitment of two nucleolar proteins is required for homolog segregation in meiosis I. Developmental Cell. 4: 535-48. PMID 12689592 DOI: 10.1016/S1534-5807(03)00086-8  0.48
2003 Schleiffer A, Kaitna S, Maurer-Stroh S, Glotzer M, Nasmyth K, Eisenhaber F. Kleisins: a superfamily of bacterial and eukaryotic SMC protein partners. Molecular Cell. 11: 571-5. PMID 12667442 DOI: 10.1016/S1097-2765(03)00108-4  0.33
2003 Gruber S, Haering CH, Nasmyth K. Chromosomal cohesin forms a ring. Cell. 112: 765-77. PMID 12654244 DOI: 10.1016/S0092-8674(03)00162-4  0.434
2003 Petronczki M, Siomos MF, Nasmyth K. Un ménage à quatre: the molecular biology of chromosome segregation in meiosis. Cell. 112: 423-40. PMID 12600308 DOI: 10.1016/S0092-8674(03)00083-7  0.453
2003 Krylov DM, Nasmyth K, Koonin EV. Evolution of eukaryotic cell cycle regulation: stepwise addition of regulatory kinases and late advent of the CDKs. Current Biology : Cb. 13: 173-7. PMID 12546794 DOI: 10.1016/S0960-9822(03)00008-3  0.402
2002 Nasmyth K. Segregating sister genomes: the molecular biology of chromosome separation. Science (New York, N.Y.). 297: 559-65. PMID 12142526 DOI: 10.1126/Science.1074757  0.489
2002 Haering CH, Löwe J, Hochwagen A, Nasmyth K. Molecular architecture of SMC proteins and the yeast cohesin complex. Molecular Cell. 9: 773-88. PMID 11983169 DOI: 10.1016/S1097-2765(02)00515-4  0.392
2002 Ivanov D, Schleiffer A, Eisenhaber F, Mechtler K, Haering CH, Nasmyth K. Eco1 is a novel acetyltransferase that can acetylate proteins involved in cohesion. Current Biology : Cb. 12: 323-8. PMID 11864574 DOI: 10.1016/S0960-9822(02)00681-4  0.406
2002 Tanaka TU, Rachidi N, Janke C, Pereira G, Galova M, Schiebel E, Stark MJ, Nasmyth K. Evidence that the Ipl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections. Cell. 108: 317-29. PMID 11853667 DOI: 10.1016/S0092-8674(02)00633-5  0.488
2001 Nasmyth K. A prize for proliferation. Cell. 107: 689-701. PMID 11747804 DOI: 10.1016/S0092-8674(01)00604-3  0.459
2001 Siomos MF, Badrinath A, Pasierbek P, Livingstone D, White J, Glotzer M, Nasmyth K. Separase is required for chromosome segregation during meiosis I in Caenorhabditis elegans. Current Biology : Cb. 11: 1825-35. PMID 11728305 DOI: 10.1016/S0960-9822(01)00588-7  0.486
2001 Pereira G, Tanaka TU, Nasmyth K, Schiebel E. Modes of spindle pole body inheritance and segregation of the Bfa1p-Bub2p checkpoint protein complex. The Embo Journal. 20: 6359-70. PMID 11707407 DOI: 10.1093/Emboj/20.22.6359  0.451
2001 Nasmyth K. Disseminating the genome: joining, resolving, and separating sister chromatids during mitosis and meiosis. Annual Review of Genetics. 35: 673-745. PMID 11700297 DOI: 10.1146/Annurev.Genet.35.102401.091334  0.416
2001 Rabitsch KP, Tóth A, Gálová M, Schleiffer A, Schaffner G, Aigner E, Rupp C, Penkner AM, Moreno-Borchart AC, Primig M, Esposito RE, Klein F, Knop M, Nasmyth K. A screen for genes required for meiosis and spore formation based on whole-genome expression. Current Biology : Cb. 11: 1001-9. PMID 11470404 DOI: 10.1016/S0960-9822(01)00274-3  0.438
2001 Sjögren C, Nasmyth K. Sister chromatid cohesion is required for postreplicative double-strand break repair in Saccharomyces cerevisiae. Current Biology : Cb. 11: 991-5. PMID 11448778 DOI: 10.1016/S0960-9822(01)00271-8  0.444
2001 Nasmyth K, Peters JM, Uhlmann F. Splitting the chromosome: cutting the ties that bind sister chromatids. Novartis Foundation Symposium. 237: 113-33; discussion 1. PMID 11444040  0.373
2001 Cosma MP, Panizza S, Nasmyth K. Cdk1 triggers association of RNA polymerase to cell cycle promoters only after recruitment of the mediator by SBF. Molecular Cell. 7: 1213-20. PMID 11430824 DOI: 10.1016/S1097-2765(01)00266-0  0.378
2001 Alexandru G, Uhlmann F, Mechtler K, Poupart MA, Nasmyth K. Phosphorylation of the cohesin subunit Scc1 by Polo/Cdc5 kinase regulates sister chromatid separation in yeast. Cell. 105: 459-72. PMID 11371343 DOI: 10.1016/S0092-8674(01)00362-2  0.497
2001 Rao H, Uhlmann F, Nasmyth K, Varshavsky A. Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability. Nature. 410: 955-9. PMID 11309624 DOI: 10.1038/35073627  0.4
2001 Nasmyth K. Chromosome segregation one hundred years after Mendel's rediscovery Arthritis Research & Therapy. 3. DOI: 10.1186/Ar155  0.515
2000 Tóth A, Rabitsch KP, Gálová M, Schleiffer A, Buonomo SB, Nasmyth K. Functional genomics identifies monopolin: a kinetochore protein required for segregation of homologs during meiosis i. Cell. 103: 1155-68. PMID 11163190 DOI: 10.1016/S0092-8674(00)00217-8  0.478
2000 Panizza S, Tanaka T, Hochwagen A, Eisenhaber F, Nasmyth K. Pds5 cooperates with cohesin in maintaining sister chromatid cohesion. Current Biology : Cb. 10: 1557-64. PMID 11137006 DOI: 10.1016/S0960-9822(00)00854-X  0.507
2000 Buonomo SB, Clyne RK, Fuchs J, Loidl J, Uhlmann F, Nasmyth K. Disjunction of homologous chromosomes in meiosis I depends on proteolytic cleavage of the meiotic cohesin Rec8 by separin. Cell. 103: 387-98. PMID 11081626 DOI: 10.1016/S0092-8674(00)00131-8  0.456
2000 Uhlmann F, Wernic D, Poupart MA, Koonin EV, Nasmyth K. Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast. Cell. 103: 375-86. PMID 11081625 DOI: 10.1016/S0092-8674(00)00130-6  0.507
2000 Tomonaga T, Nagao K, Kawasaki Y, Furuya K, Murakami A, Morishita J, Yuasa T, Sutani T, Kearsey SE, Uhlmann F, Nasmyth K, Yanagida M. Characterization of fission yeast cohesin: essential anaphase proteolysis of Rad21 phosphorylated in the S phase. Genes & Development. 14: 2757-70. PMID 11069892 DOI: 10.1101/Gad.832000  0.509
2000 Tanaka T, Fuchs J, Loidl J, Nasmyth K. Cohesin ensures bipolar attachment of microtubules to sister centromeres and resists their precocious separation. Nature Cell Biology. 2: 492-9. PMID 10934469 DOI: 10.1038/35019529  0.472
2000 Ciosk R, Shirayama M, Shevchenko A, Tanaka T, Toth A, Shevchenko A, Nasmyth K. Cohesin's binding to chromosomes depends on a separate complex consisting of Scc2 and Scc4 proteins. Molecular Cell. 5: 243-54. PMID 10882066 DOI: 10.1016/S1097-2765(00)80420-7  0.458
2000 Salah SM, Nasmyth K. Destruction of the securin Pds1p occurs at the onset of anaphase during both meiotic divisions in yeast. Chromosoma. 109: 27-34. PMID 10855492 DOI: 10.1007/S004120050409  0.504
2000 Nasmyth K, Peters JM, Uhlmann F. Splitting the chromosome: cutting the ties that bind sister chromatids. Science (New York, N.Y.). 288: 1379-85. PMID 10827941 DOI: 10.1126/Science.288.5470.1379  0.49
1999 Shirayama M, Tóth A, Gálová M, Nasmyth K. APC(Cdc20) promotes exit from mitosis by destroying the anaphase inhibitor Pds1 and cyclin Clb5. Nature. 402: 203-7. PMID 10647015 DOI: 10.1038/46080  0.443
1999 Tanaka T, Cosma MP, Wirth K, Nasmyth K. Identification of cohesin association sites at centromeres and along chromosome arms. Cell. 98: 847-58. PMID 10499801 DOI: 10.1016/S0092-8674(00)81518-4  0.444
1999 Zachariae W, Nasmyth K. Whose end is destruction: cell division and the anaphase-promoting complex. Genes & Development. 13: 2039-58. PMID 10465783 DOI: 10.1101/Gad.13.16.2039  0.461
1999 Klein F, Mahr P, Galova M, Buonomo SB, Michaelis C, Nairz K, Nasmyth K. A central role for cohesins in sister chromatid cohesion, formation of axial elements, and recombination during yeast meiosis. Cell. 98: 91-103. PMID 10412984 DOI: 10.1016/S0092-8674(00)80609-1  0.478
1999 Knop M, Siegers K, Pereira G, Zachariae W, Winsor B, Nasmyth K, Schiebel E. Epitope tagging of yeast genes using a PCR-based strategy: more tags and improved practical routines. Yeast (Chichester, England). 15: 963-72. PMID 10407276 DOI: 10.1002/(Sici)1097-0061(199907)15:10B<963::Aid-Yea399>3.0.Co;2-W  0.336
1999 Uhlmann F, Lottspeich F, Nasmyth K. Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1. Nature. 400: 37-42. PMID 10403247 DOI: 10.1038/21831  0.503
1999 Novák B, Tóth A, Csikász-Nagy A, Györffy B, Tyson JJ, Nasmyth K. Finishing the cell cycle. Journal of Theoretical Biology. 199: 223-33. PMID 10395816 DOI: 10.1006/Jtbi.1999.0956  0.447
1999 Seol JH, Feldman RM, Zachariae W, Shevchenko A, Correll CC, Lyapina S, Chi Y, Galova M, Claypool J, Sandmeyer S, Nasmyth K, Deshaies RJ, Shevchenko A, Deshaies RJ. Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34. Genes & Development. 13: 1614-26. PMID 10385629 DOI: 10.1101/Gad.13.12.1614  0.422
1999 Alexandru G, Zachariae W, Schleiffer A, Nasmyth K. Sister chromatid separation and chromosome re-duplication are regulated by different mechanisms in response to spindle damage. The Embo Journal. 18: 2707-21. PMID 10329618 DOI: 10.1093/Emboj/18.10.2707  0.515
1999 Cosma MP, Tanaka T, Nasmyth K. Ordered recruitment of transcription and chromatin remodeling factors to a cell cycle- and developmentally regulated promoter. Cell. 97: 299-311. PMID 10319811 DOI: 10.1016/S0092-8674(00)80740-0  0.4
1999 Grossberger R, Gieffers C, Zachariae W, Podtelejnikov AV, Schleiffer A, Nasmyth K, Mann M, Peters JM. Characterization of the DOC1/APC10 subunit of the yeast and the human anaphase-promoting complex. The Journal of Biological Chemistry. 274: 14500-7. PMID 10318877 DOI: 10.1074/Jbc.274.20.14500  0.41
1999 Gonzalez I, Buonomo SB, Nasmyth K, von Ahsen U. ASH1 mRNA localization in yeast involves multiple secondary structural elements and Ash1 protein translation. Current Biology : Cb. 9: 337-40. PMID 10209099 DOI: 10.1016/S0960-9822(99)80145-6  0.306
1999 Nasmyth K. Separating sister chromatids. Trends in Biochemical Sciences. 24: 98-104. PMID 10203756 DOI: 10.1016/S0968-0004(99)01358-4  0.465
1999 Tóth A, Ciosk R, Uhlmann F, Galova M, Schleiffer A, Nasmyth K. Yeast cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication. Genes & Development. 13: 320-33. PMID 9990856 DOI: 10.1101/Gad.13.3.320  0.496
1998 Novak B, Csikasz-Nagy A, Gyorffy B, Nasmyth K, Tyson JJ. Model scenarios for evolution of the eukaryotic cell cycle. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 353: 2063-76. PMID 10098216 DOI: 10.1098/Rstb.1998.0352  0.509
1998 Zachariae W, Schwab M, Nasmyth K, Seufert W. Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex. Science (New York, N.Y.). 282: 1721-4. PMID 9831566 DOI: 10.1126/Science.282.5394.1721  0.455
1998 Uhlmann F, Nasmyth K. Cohesion between sister chromatids must be established during DNA replication. Current Biology : Cb. 8: 1095-101. PMID 9778527 DOI: 10.1016/S0960-9822(98)70463-4  0.506
1998 Tanaka T, Nasmyth K. Association of RPA with chromosomal replication origins requires an Mcm protein, and is regulated by Rad53, and cyclin- and Dbf4-dependent kinases. The Embo Journal. 17: 5182-91. PMID 9724654 DOI: 10.1093/Emboj/17.17.5182  0.478
1998 Ciosk R, Zachariae W, Michaelis C, Shevchenko A, Mann M, Nasmyth K. An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast. Cell. 93: 1067-76. PMID 9635435 DOI: 10.1016/S0092-8674(00)81211-8  0.416
1998 Shirayama M, Zachariae W, Ciosk R, Nasmyth K. The Polo-like kinase Cdc5p and the WD-repeat protein Cdc20p/fizzy are regulators and substrates of the anaphase promoting complex in Saccharomyces cerevisiae. The Embo Journal. 17: 1336-49. PMID 9482731 DOI: 10.1093/Emboj/17.5.1336  0.492
1998 Zachariae W, Shevchenko A, Andrews PD, Ciosk R, Galova M, Stark MJ, Mann M, Nasmyth K. Mass spectrometric analysis of the anaphase-promoting complex from yeast: identification of a subunit related to cullins. Science (New York, N.Y.). 279: 1216-9. PMID 9469814 DOI: 10.1126/Science.279.5354.1216  0.411
1998 Irniger S, Piatti S, Michaelis C, Nasmyth K. No Evidence that Cse1p Is Required for Cyclin Proteolysis Cell. 93: 486. DOI: 10.1016/S0092-8674(00)81176-9  0.376
1997 Michaelis C, Ciosk R, Nasmyth K. Cohesins: chromosomal proteins that prevent premature separation of sister chromatids. Cell. 91: 35-45. PMID 9335333 DOI: 10.1016/S0092-8674(01)80007-6  0.471
1997 Pichler S, Piatti S, Nasmyth K. Is the yeast anaphase promoting complex needed to prevent re-replication during G2 and M phases? The Embo Journal. 16: 5988-97. PMID 9312056 DOI: 10.1093/Emboj/16.19.5988  0.494
1997 Tanaka T, Knapp D, Nasmyth K. Loading of an Mcm protein onto DNA replication origins is regulated by Cdc6p and CDKs. Cell. 90: 649-60. PMID 9288745 DOI: 10.1016/S0092-8674(00)80526-7  0.408
1997 Irniger S, Nasmyth K. The anaphase-promoting complex is required in G1 arrested yeast cells to inhibit B-type cyclin accumulation and to prevent uncontrolled entry into S-phase. Journal of Cell Science. 110: 1523-31. PMID 9224769  0.377
1997 Long RM, Singer RH, Meng X, Gonzalez I, Nasmyth K, Jansen RP. Mating type switching in yeast controlled by asymmetric localization of ASH1 mRNA. Science (New York, N.Y.). 277: 383-7. PMID 9219698 DOI: 10.1126/Science.277.5324.383  0.56
1997 Nasmyth K, Jansen RP. The cytoskeleton in mRNA localization and cell differentiation. Current Opinion in Cell Biology. 9: 396-400. PMID 9159073 DOI: 10.1016/S0955-0674(97)80013-0  0.534
1997 Xu RM, Koch C, Liu Y, Horton JR, Knapp D, Nasmyth K, Cheng X. Crystal structure of the DNA-binding domain of Mbp1, a transcription factor important in cell-cycle control of DNA synthesis. Structure (London, England : 1993). 5: 349-58. PMID 9083114 DOI: 10.1016/S0969-2126(97)00192-5  0.409
1996 Nasmyth K. Viewpoint: putting the cell cycle in order. Science (New York, N.Y.). 274: 1643-5. PMID 8984634 DOI: 10.1126/Science.274.5293.1643  0.333
1996 Nasmyth K. At the heart of the budding yeast cell cycle. Trends in Genetics : Tig. 12: 405-12. PMID 8909137 DOI: 10.1016/0168-9525(96)10041-X  0.441
1996 Zachariae W, Shin TH, Galova M, Obermaier B, Nasmyth K. Identification of subunits of the anaphase-promoting complex of Saccharomyces cerevisiae. Science (New York, N.Y.). 274: 1201-4. PMID 8895471 DOI: 10.1126/Science.274.5290.1201  0.434
1996 Knapp D, Bhoite L, Stillman DJ, Nasmyth K. The transcription factor Swi5 regulates expression of the cyclin kinase inhibitor p40SIC1. Molecular and Cellular Biology. 16: 5701-7. PMID 8816483 DOI: 10.1128/Mcb.16.10.5701  0.47
1996 Nasmyth K. A homage to Giardia. Current Biology : Cb. 6: 1042. PMID 8805380 DOI: 10.1016/S0960-9822(02)70653-2  0.336
1996 Zachariae W, Nasmyth K. TPR proteins required for anaphase progression mediate ubiquitination of mitotic B-type cyclins in yeast. Molecular Biology of the Cell. 7: 791-801. PMID 8744951 DOI: 10.1091/Mbc.7.5.791  0.484
1996 Kovacech B, Nasmyth K, Schuster T. EGT2 gene transcription is induced predominantly by Swi5 in early G1. Molecular and Cellular Biology. 16: 3264-74. PMID 8668141 DOI: 10.1128/Mcb.16.7.3264  0.413
1996 Piatti S, Böhm T, Cocker JH, Diffley JF, Nasmyth K. Activation of S-phase-promoting CDKs in late G1 defines a "point of no return" after which Cdc6 synthesis cannot promote DNA replication in yeast. Genes & Development. 10: 1516-31. PMID 8666235 DOI: 10.1101/Gad.10.12.1516  0.472
1996 Siegmund RF, Nasmyth KA. The Saccharomyces cerevisiae Start-specific transcription factor Swi4 interacts through the ankyrin repeats with the mitotic Clb2/Cdc28 kinase and through its conserved carboxy terminus with Swi6. Molecular and Cellular Biology. 16: 2647-55. PMID 8649372  0.333
1996 Bobola N, Jansen RP, Shin TH, Nasmyth K. Asymmetric accumulation of Ash1p in postanaphase nuclei depends on a myosin and restricts yeast mating-type switching to mother cells. Cell. 84: 699-709. PMID 8625408 DOI: 10.1042/Bst024507Sa  0.568
1996 Jansen RP, Dowzer C, Michaelis C, Galova M, Nasmyth K. Mother cell-specific HO expression in budding yeast depends on the unconventional myosin myo4p and other cytoplasmic proteins. Cell. 84: 687-97. PMID 8625407 DOI: 10.1016/S0092-8674(00)81047-8  0.563
1996 Koch C, Schleiffer A, Ammerer G, Nasmyth K. Switching transcription on and off during the yeast cell cycle: Cln/Cdc28 kinases activate bound transcription factor SBF (Swi4/Swi6) at start, whereas Clb/Cdc28 kinases displace it from the promoter in G2. Genes & Development. 10: 129-41. PMID 8566747 DOI: 10.1101/Gad.10.2.129  0.456
1996 Cocker JH, Piatti S, Santocanale C, Nasmyth K, Diffley JF. An essential role for the Cdc6 protein in forming the pre-replicative complexes of budding yeast. Nature. 379: 180-2. PMID 8538771 DOI: 10.1038/379180A0  0.444
1995 Nasmyth K. Evolution of the cell cycle. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 349: 271-81. PMID 8577838 DOI: 10.1098/Rstb.1995.0113  0.443
1995 Dahmann C, Diffley JF, Nasmyth KA. S-phase-promoting cyclin-dependent kinases prevent re-replication by inhibiting the transition of replication origins to a pre-replicative state. Current Biology : Cb. 5: 1257-69. PMID 8574583 DOI: 10.1016/S0960-9822(95)00252-1  0.321
1995 Maher M, Cong F, Kindelberger D, Nasmyth K, Dalton S. Cell cycle-regulated transcription of the CLB2 gene is dependent on Mcm1 and a ternary complex factor. Molecular and Cellular Biology. 15: 3129-37. PMID 7760809 DOI: 10.1128/Mcb.15.6.3129  0.47
1995 Irniger S, Piatti S, Michaelis C, Nasmyth K. Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast. Cell. 81: 269-78. PMID 7736579 DOI: 10.1016/0092-8674(95)90337-2  0.439
1995 Cvrcková F, De Virgilio C, Manser E, Pringle JR, Nasmyth K. Ste20-like protein kinases are required for normal localization of cell growth and for cytokinesis in budding yeast. Genes & Development. 9: 1817-30. PMID 7649470 DOI: 10.1101/Gad.9.15.1817  0.696
1995 Piatti S, Lengauer C, Nasmyth K. Cdc6 is an unstable protein whose de novo synthesis in G1 is important for the onset of S phase and for preventing a 'reductional' anaphase in the budding yeast Saccharomyces cerevisiae. The Embo Journal. 14: 3788-99. PMID 7641697 DOI: 10.1002/J.1460-2075.1995.Tb00048.X  0.493
1995 Jans DA, Moll T, Nasmyth K, Jans P. Cyclin-dependent kinase site-regulated signal-dependent nuclear localization of the SW15 yeast transcription factor in mammalian cells. The Journal of Biological Chemistry. 270: 17064-7. PMID 7615496 DOI: 10.1074/Jbc.270.29.17064  0.426
1995 Dirick L, Böhm T, Nasmyth K. Roles and regulation of Cln-Cdc28 kinases at the start of the cell cycle of Saccharomyces cerevisiae. The Embo Journal. 14: 4803-13. PMID 7588610 DOI: 10.1002/J.1460-2075.1995.Tb00162.X  0.451
1994 Amon A, Irniger S, Nasmyth K. Closing the cell cycle circle in yeast: G2 cyclin proteolysis initiated at mitosis persists until the activation of G1 cyclins in the next cycle. Cell. 77: 1037-50. PMID 8020094 DOI: 10.1016/0092-8674(94)90443-X  0.598
1994 Schwob E, Böhm T, Mendenhall MD, Nasmyth K. The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae. Cell. 79: 233-44. PMID 7954792 DOI: 10.1016/0092-8674(94)90193-7  0.454
1994 Zhu Y, Takeda T, Nasmyth K, Jones N. pct1+, which encodes a new DNA-binding partner of p85cdc10, is required for meiosis in the fission yeast Schizosaccharomyces pombe. Genes & Development. 8: 885-98. PMID 7926774 DOI: 10.1101/Gad.8.8.885  0.449
1994 Koch C, Nasmyth K. Cell cycle regulated transcription in yeast. Current Opinion in Cell Biology. 6: 451-9. PMID 7917338 DOI: 10.1016/0955-0674(94)90039-6  0.452
1993 Nasmyth K. Control of the yeast cell cycle by the Cdc28 protein kinase. Current Opinion in Cell Biology. 5: 166-79. PMID 8507488 DOI: 10.1016/0955-0674(93)90099-C  0.457
1993 Nasmyth K. Regulating the HO endonuclease in yeast. Current Opinion in Genetics & Development. 3: 286-94. PMID 8504254 DOI: 10.1016/0959-437X(93)90036-O  0.434
1993 Surana U, Amon A, Dowzer C, McGrew J, Byers B, Nasmyth K. Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase to anaphase transition in budding yeast. The Embo Journal. 12: 1969-78. PMID 8491189 DOI: 10.1002/J.1460-2075.1993.Tb05846.X  0.577
1993 Tebb G, Moll T, Dowzer C, Nasmyth K. SWI5 instability may be necessary but is not sufficient for asymmetric HO expression in yeast. Genes & Development. 7: 517-28. PMID 8449406 DOI: 10.1101/Gad.7.3.517  0.427
1993 Amon A, Tyers M, Futcher B, Nasmyth K. Mechanisms that help the yeast cell cycle clock tick: G2 cyclins transcriptionally activate G2 cyclins and repress G1 cyclins. Cell. 74: 993-1007. PMID 8402888 DOI: 10.1016/0092-8674(93)90722-3  0.597
1993 Errede B, Gartner A, Zhou Z, Nasmyth K, Ammerer G. MAP kinase-related FUS3 from S. cerevisiae is activated by STE7 in vitro. Nature. 362: 261-4. PMID 8384702 DOI: 10.1038/362261A0  0.312
1993 Koch C, Moll T, Neuberg M, Ahorn H, Nasmyth K. A role for the transcription factors Mbp1 and Swi4 in progression from G1 to S phase. Science (New York, N.Y.). 261: 1551-7. PMID 8372350 DOI: 10.1126/Science.8372350  0.446
1993 Schwob E, Nasmyth K. CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiae. Genes & Development. 7: 1160-75. PMID 8319908 DOI: 10.1101/Gad.7.7A.1160  0.502
1993 Cvrcková F, Nasmyth K. Yeast G1 cyclins CLN1 and CLN2 and a GAP-like protein have a role in bud formation. The Embo Journal. 12: 5277-86. PMID 8262070 DOI: 10.1002/J.1460-2075.1993.Tb06223.X  0.732
1993 Nasmyth K, Hunt T. Cell cycle. Dams and sluices. Nature. 366: 634-5. PMID 8259207 DOI: 10.1038/366634A0  0.36
1993 Micklem G, Rowley A, Harwood J, Nasmyth K, Diffley JF. Yeast origin recognition complex is involved in DNA replication and transcriptional silencing. Nature. 366: 87-9. PMID 8232543 DOI: 10.1038/366087A0  0.703
1993 Moll T, Schwob E, Koch C, Moore A, Auer H, Nasmyth K. Transcription factors important for starting the cell cycle in yeast. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 340: 351-60. PMID 8103939 DOI: 10.1098/Rstb.1993.0078  0.498
1992 Amon A, Surana U, Muroff I, Nasmyth K. Regulation of p34CDC28 tyrosine phosphorylation is not required for entry into mitosis in S. cerevisiae. Nature. 355: 368-71. PMID 1731251 DOI: 10.1038/355368A0  0.627
1992 Gartner A, Nasmyth K, Ammerer G. Signal transduction in Saccharomyces cerevisiae requires tyrosine and threonine phosphorylation of FUS3 and KSS1. Genes & Development. 6: 1280-92. PMID 1628831 DOI: 10.1101/Gad.6.7.1280  0.313
1992 Dirick L, Moll T, Auer H, Nasmyth K. A central role for SWI6 in modulating cell cycle Start-specific transcription in yeast. Nature. 357: 508-13. PMID 1608451 DOI: 10.1038/357508A0  0.489
1992 Patel G, Nasmyth K, Jones N. A new method for the isolation of recombinant baculovirus. Nucleic Acids Research. 20: 97-104. PMID 1531384 DOI: 10.1093/Nar/20.1.97  0.353
1992 Fitch I, Dahmann C, Surana U, Amon A, Nasmyth K, Goetsch L, Byers B, Futcher B. Characterization of four B-type cyclin genes of the budding yeast Saccharomyces cerevisiae. Molecular Biology of the Cell. 3: 805-18. PMID 1387566 DOI: 10.1091/Mbc.3.7.805  0.626
1992 Primig M, Sockanathan S, Auer H, Nasmyth K. Anatomy of a transcription factor important for the start of the cell cycle in Saccharomyces cerevisiae. Nature. 358: 593-7. PMID 1386897 DOI: 10.1038/358593A0  0.434
1992 Moll T, Dirick L, Auer H, Bonkovsky J, Nasmyth K. SWI6 is a regulatory subunit of two different cell cycle START-dependent transcription factors in Saccharomyces cerevisiae. Journal of Cell Science. Supplement. 16: 87-96. PMID 1297653 DOI: 10.1242/Jcs.1992.Supplement_16.11  0.48
1991 Price C, Nasmyth K, Schuster T. A general approach to the isolation of cell cycle-regulated genes in the budding yeast, Saccharomyces cerevisiae. Journal of Molecular Biology. 218: 543-56. PMID 2016745 DOI: 10.1016/0022-2836(91)90700-G  0.454
1991 Taba MR, Muroff I, Lydall D, Tebb G, Nasmyth K. Changes in a SWI4,6-DNA-binding complex occur at the time of HO gene activation in yeast. Genes & Development. 5: 2000-13. PMID 1936990 DOI: 10.1101/Gad.5.11.2000  0.456
1991 Surana U, Robitsch H, Price C, Schuster T, Fitch I, Futcher AB, Nasmyth K. The role of CDC28 and cyclins during mitosis in the budding yeast S. cerevisiae. Cell. 65: 145-61. PMID 1849457 DOI: 10.1016/0092-8674(91)90416-V  0.433
1991 Nasmyth K, Dirick L, Surana U, Amon A, Cvrckova F. Some facts and thoughts on cell cycle control in yeast. Cold Spring Harbor Symposia On Quantitative Biology. 56: 9-20. PMID 1840270 DOI: 10.1101/Sqb.1991.056.01.004  0.729
1991 Nasmyth K, Dirick L. The role of SWI4 and SWI6 in the activity of G1 cyclins in yeast. Cell. 66: 995-1013. PMID 1832338 DOI: 10.1016/0092-8674(91)90444-4  0.46
1991 Dirick L, Nasmyth K. Positive feedback in the activation of G1 cyclins in yeast. Nature. 351: 754-7. PMID 1829507 DOI: 10.1038/351754A0  0.434
1991 Lydall D, Ammerer G, Nasmyth K. A new role for MCM1 in yeast: cell cycle regulation of SW15 transcription. Genes & Development. 5: 2405-19. PMID 1752436 DOI: 10.1101/Gad.5.12B.2405  0.467
1991 Moll T, Tebb G, Surana U, Robitsch H, Nasmyth K. The role of phosphorylation and the CDC28 protein kinase in cell cycle-regulated nuclear import of the S. cerevisiae transcription factor SWI5. Cell. 66: 743-58. PMID 1652372 DOI: 10.1016/0092-8674(91)90118-I  0.451
1990 Nasmyth K, Adolf G, Lydall D, Seddon A. The identification of a second cell cycle control on the HO promoter in yeast: cell cycle regulation of SW15 nuclear entry. Cell. 62: 631-47. PMID 2167175 DOI: 10.1016/0092-8674(90)90110-Z  0.432
1988 Stillman DJ, Bankier AT, Seddon A, Groenhout EG, Nasmyth KA. Characterization of a transcription factor involved in mother cell specific transcription of the yeast HO gene. The Embo Journal. 7: 485-94. PMID 3284746  0.313
1988 Nagai K, Nakaseko Y, Nasmyth K, Rhodes D. Zinc-finger motifs expressed in E. coli and folded in vitro direct specific binding to DNA. Nature. 332: 284-6. PMID 2831463 DOI: 10.1038/332284A0  0.361
1987 Shore D, Stillman DJ, Brand AH, Nasmyth KA. Identification of silencer binding proteins from yeast: possible roles in SIR control and DNA replication. The Embo Journal. 6: 461-7. PMID 15981337 DOI: 10.1002/J.1460-2075.1987.Tb04776.X  0.539
1987 Nasmyth K. The determination of mother cell-specific mating type switching in yeast by a specific regulator of HO transcription. The Embo Journal. 6: 243-8. PMID 15981333 DOI: 10.1002/J.1460-2075.1987.Tb04745.X  0.389
1987 Nasmyth K, Seddon A, Ammerer G. Cell cycle regulation of SW15 is required for mother-cell-specific HO transcription in yeast. Cell. 49: 549-58. PMID 3552251 DOI: 10.1016/0092-8674(87)90457-0  0.405
1987 Breeden L, Nasmyth K. Cell cycle control of the yeast HO gene: cis- and trans-acting regulators. Cell. 48: 389-97. PMID 3542227 DOI: 10.1016/0092-8674(87)90190-5  0.389
1987 Shore D, Nasmyth K. Purification and cloning of a DNA binding protein from yeast that binds to both silencer and activator elements. Cell. 51: 721-32. PMID 3315231 DOI: 10.1016/0092-8674(87)90095-X  0.388
1987 Brand AH, Micklem G, Nasmyth K. A yeast silencer contains sequences that can promote autonomous plasmid replication and transcriptional activation. Cell. 51: 709-19. PMID 3315230 DOI: 10.1016/0092-8674(87)90094-8  0.729
1987 Nasmyth K, Shore D. Transcriptional regulation in the yeast life cycle. Science (New York, N.Y.). 237: 1162-70. PMID 3306917 DOI: 10.1126/Science.3306917  0.407
1987 Nasmyth K, Stillman D, Kipling D. Both positive and negative regulators of HO transcription are required for mother-cell-specific mating-type switching in yeast. Cell. 48: 579-87. PMID 3028642 DOI: 10.1016/0092-8674(87)90236-4  0.413
1987 Breeden L, Nasmyth K. Similarity between cell-cycle genes of budding yeast and fission yeast and the Notch gene of Drosophila. Nature. 329: 651-4. PMID 2821408 DOI: 10.1038/329651A0  0.478
1986 Nasmyth K. A U-turn in the regulation of transcription? Trends in Genetics. 2: 115-116. DOI: 10.1016/0168-9525(86)90197-6  0.308
1985 Breeden L, Nasmyth K. Regulation of the yeast HO gene. Cold Spring Harbor Symposia On Quantitative Biology. 50: 643-50. PMID 3938367 DOI: 10.1101/Sqb.1985.050.01.078  0.329
1985 Nasmyth K. A repetitive DNA sequence that confers cell-cycle START (CDC28)-dependent transcription of the HO gene in yeast. Cell. 42: 225-35. PMID 3893742 DOI: 10.1016/S0092-8674(85)80118-5  0.436
1985 Nasmyth K. At least 1400 base pairs of 5'-flanking DNA is required for the correct expression of the HO gene in yeast. Cell. 42: 213-23. PMID 3893741 DOI: 10.1016/S0092-8674(85)80117-3  0.436
1985 Brand AH, Breeden L, Abraham J, Sternglanz R, Nasmyth K. Characterization of a "silencer" in yeast: a DNA sequence with properties opposite to those of a transcriptional enhancer. Cell. 41: 41-8. PMID 3888409 DOI: 10.1016/0092-8674(85)90059-5  0.57
1983 Nasmyth K. Molecular analysis of a cell lineage. Nature. 302: 670-6. PMID 6339953 DOI: 10.1038/302670A0  0.408
1981 Nasmyth K, Nurse P. Cell division cycle mutants altered in DNA replication and mitosis in the fission yeast Schizosaccharomyces pombe. Molecular & General Genetics : Mgg. 182: 119-24. PMID 6943408 DOI: 10.1007/Bf00422777  0.607
1980 Williamson VM, Bennetzen J, Young ET, Nasmyth K, Hall BD. Isolation of the structural gene for alcohol dehydrogenase by genetic complementation in yeast. Nature. 283: 214-6. PMID 6985717 DOI: 10.1038/283214A0  0.34
1978 Johnston LH, Nasmyth KA. Saccharomyces cerevisiae cell cycle mutant cdc9 is defective in DNA ligase. Nature. 274: 891-3. PMID 355897  0.314
1978 Nasmyth K. Eukaryotic gene cloning and expression in yeast. Nature. 274: 741-3. PMID 355889 DOI: 10.1038/274741A0  0.305
1976 Nurse P, Thuriaux P, Nasmyth K. Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombe. Molecular & General Genetics : Mgg. 146: 167-78. PMID 958201 DOI: 10.1007/Bf00268085  0.612
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